BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: e7a9f15578ab809b1411e8ac6bee00bb.SwissProt.fasta
22 sequences; 8,598 total letters
Query= ACIAD1569
Length=388
Score E
Sequences producing significant alignments: (Bits) Value
I6XHJ3 Steroid 3-ketoacyl-CoA thiolase FadA6 [Mycobacterium tuber... 394 4e-139
B6EGU1 3-ketoacyl-CoA thiolase [Aliivibrio salmonicida (strain LF... 265 7e-89
A3Q8U3 3-ketoacyl-CoA thiolase [Shewanella loihica (strain ATCC B... 263 3e-88
I6XHI4 Steroid 3-ketoacyl-CoA thiolase [Mycobacterium tuberculosi... 263 4e-88
Q6DAP6 3-ketoacyl-CoA thiolase [Pectobacterium atrosepticum (stra... 261 2e-87
Q7MZ91 3-ketoacyl-CoA thiolase [Photorhabdus laumondii subsp. lau... 261 2e-87
A1S1I7 3-ketoacyl-CoA thiolase [Shewanella amazonensis (strain AT... 261 2e-87
Q5QXH8 3-ketoacyl-CoA thiolase [Idiomarina loihiensis (strain ATC... 259 9e-87
A4TR28 3-ketoacyl-CoA thiolase [Yersinia pestis (strain Pestoides... 258 2e-86
Q1CNA0 3-ketoacyl-CoA thiolase [Yersinia pestis bv. Antiqua (stra... 258 2e-86
Q8ZAM9 3-ketoacyl-CoA thiolase [Yersinia pestis] 258 2e-86
Q1C2C3 3-ketoacyl-CoA thiolase [Yersinia pestis bv. Antiqua (stra... 258 2e-86
A7FDF1 3-ketoacyl-CoA thiolase [Yersinia pseudotuberculosis serot... 258 2e-86
A1TZR8 3-ketoacyl-CoA thiolase [Marinobacter nauticus (strain ATC... 258 3e-86
O32177 3-ketoacyl-CoA thiolase [Bacillus subtilis (strain 168)] 255 4e-85
Q9F0Y6 3-ketoacyl-CoA thiolase [Enterobacter cloacae] 248 2e-82
P0C7L2 3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA thiolase [Esc... 247 8e-82
Q43935 Beta-ketoadipyl-CoA thiolase [Acinetobacter baylyi (strain... 246 2e-81
P0C7L3 Beta-ketoadipyl-CoA thiolase [Escherichia coli] 244 9e-81
P28790 3-ketoacyl-CoA thiolase [Pseudomonas fragi] 243 2e-80
P21151 3-ketoacyl-CoA thiolase FadA [Escherichia coli (strain K12)] 241 2e-79
Q9ZHI1 Acetyl-CoA acetyltransferase [Chromobacterium violaceum (s... 239 6e-79
>I6XHJ3 Steroid 3-ketoacyl-CoA thiolase FadA6 [Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv)]
Length=407
Score = 394 bits (1012), Expect = 4e-139
Identities = 207/385 (54%), Positives = 271/385 (70%), Gaps = 2/385 (1%)
Query 1 MNVAYIVDAVRTAGGRRNGKLASWHPVDLGAEVINALLDRTGIDPNVIDDAVFGCVTQAG 60
M AY++DAVRTA G+R G LA HPVDLGA LLDRT IDP +DD + GCV G
Sbjct 22 MTEAYVIDAVRTAVGKRGGALAGIHPVDLGALAWRGLLDRTDIDPAAVDDVIAGCVDAIG 81
Query 61 EQTFAFARNIVLASKLPIHVPGVTIDRQCGSSQQAVQFAAQAILSGMQDVVIAGGVESMS 120
Q AR LA+ P VPGVT+DRQCGSSQQA+ F AQAI+SG DV++AGGV++MS
Sbjct 82 GQAGNIARLSWLAAGYPEEVPGVTVDRQCGSSQQAISFGAQAIMSGTADVIVAGGVQNMS 141
Query 121 RAPMLSNASLHAKAGLPADPL-SPRIKARFDVDQFSQFTGAEMMAKKYGFDREQLDQYAL 179
+ P+ S ++ + G + S + R+ + SQF G+E++A+K+ RE++++Y+L
Sbjct 142 QIPISSAMTVGEQFGFTSPTNESKQWLHRYGDQEISQFRGSELIAEKWNLSREEMERYSL 201
Query 180 LSHQRAIQATETGNFENEIVVLDVDGEAHRIDEGIRFDANLESVSGLKPLVENGVVTAAN 239
SH+RA A G+FENEI+ ++ + R+DEG R +++LE ++GL+PLVE G +TAA
Sbjct 202 TSHERAFAAIRAGHFENEIITVETESGPFRVDEGPR-ESSLEKMAGLQPLVEGGRLTAAM 260
Query 240 ASQICDGASAVLIVSERALKAYDLTPKARLIHMSVSAGDPVMMLEEPIFATQKALKKAGL 299
ASQI DGASAVL+ SERA+K + L P+AR+ H+S A DPV ML PI AT+ AL K GL
Sbjct 261 ASQISDGASAVLLASERAVKDHGLRPRARIHHISARAADPVFMLTGPIPATRYALDKTGL 320
Query 300 KITDIDLYEVNEAFAPVPLAWLQALDANPEALNIHGGAIALGHPLGASGTKLMTTLIHAL 359
I DID E+NEAFAPV +AWL+ + A+P +N +GGAIALGHPLGA+G KL TT++ L
Sbjct 321 AIDDIDTVEINEAFAPVVMAWLKEIKADPAKVNPNGGAIALGHPLGATGAKLFTTMLGEL 380
Query 360 HTQGKRYGLQTMCEGGGMANVTILE 384
G RYGLQTMCEGGG ANVTI+E
Sbjct 381 ERIGGRYGLQTMCEGGGTANVTIIE 405
>B6EGU1 3-ketoacyl-CoA thiolase [Aliivibrio salmonicida (strain
LFI1238)]
Length=387
Score = 265 bits (677), Expect = 7e-89
Identities = 166/398 (42%), Positives = 231/398 (58%), Gaps = 27/398 (7%)
Query 1 MNVAYIVDAVRTAGGR-RNGKLASWHPVDLGAEVINALLDRT-GIDPNVIDDAVFGCVTQ 58
M IVD +RT GR +NG DL A ++ LL+R +DPN I+D +GCV Q
Sbjct 1 MKNVVIVDCIRTPMGRSKNGVFRHTRAEDLSAHLMKGLLERNPNVDPNQIEDIYWGCVQQ 60
Query 59 AGEQTFAFARNIVLASKLPIHVPGVTIDRQCGSSQQAVQFAAQAILSGMQDVVIAGGVES 118
EQ F ARN L + LP + T++R CGSS QA+ A++AI+ G D+ I GGVE
Sbjct 61 TLEQGFNIARNASLLAGLPKSIAATTVNRLCGSSMQALHDASRAIMVGDADICIIGGVEH 120
Query 119 MSRAPMLSNASLHAKAGLPADPLSPRIKARFDVDQFSQFTG--AEMMAKKYGFDREQLDQ 176
M PM H+ GL + V + S G AEM+ K +G REQ D
Sbjct 121 MGHVPMNHGVDFHS--GLSKN-----------VAKASGMMGLTAEMLGKMHGISREQQDA 167
Query 177 YALLSHQRAIQATETGNFENEIVVLDVDGEAHRI-----DEGIRFDANLESVSGLKPLVE 231
+A SHQ+A +AT G+F++EI+ ++ E + DE IR + LE ++ L+P +
Sbjct 168 FAFASHQKAHRATIEGHFDSEILPMEGHDENGALTLVKHDEVIRPETTLEGLAALRPAFD 227
Query 232 --NGVVTAANASQICDGASAVLIVSERALKAYDLTPKARLIHMSVSAGDPVMMLEEPIFA 289
NG VTA ++S + DGASA+LI+SE LT +A++ M+VS DP +M P+ A
Sbjct 228 PANGTVTAGSSSALSDGASAMLIMSEEKANELGLTIRAKIRSMAVSGCDPAIMGYGPVPA 287
Query 290 TQKALKKAGLKITDIDLYEVNEAFAPVPLAWLQAL---DANPEALNIHGGAIALGHPLGA 346
T+KALK+AGL I DIDL+E+NEAFA L ++ L D E +N++GGAIALGHPLG
Sbjct 288 TKKALKRAGLSIDDIDLFELNEAFAAQSLPCIKDLGLFDVMEEKINLNGGAIALGHPLGC 347
Query 347 SGTKLMTTLIHALHTQGKRYGLQTMCEGGGMANVTILE 384
SG+++ TTLI+ + G + G+ TMC G G T+ E
Sbjct 348 SGSRIATTLINNMERTGAKLGVATMCIGLGQGIATVFE 385
>A3Q8U3 3-ketoacyl-CoA thiolase [Shewanella loihica (strain ATCC
BAA-1088 / PV-4)]
Length=387
Score = 263 bits (673), Expect = 3e-88
Identities = 168/398 (42%), Positives = 232/398 (58%), Gaps = 27/398 (7%)
Query 1 MNVAYIVDAVRTAGGR-RNGKLASWHPVDLGAEVINALLDRTG-IDPNVIDDAVFGCVTQ 58
M A IVD +RT GR + G + L AE++ ALL R +DPN I+D ++GCV Q
Sbjct 1 MKQAVIVDCIRTPMGRSKAGVFRNMRAESLSAELMKALLVRNPQLDPNTIEDVIWGCVQQ 60
Query 59 AGEQTFAFARNIVLASKLPIHVPGVTIDRQCGSSQQAVQFAAQAILSGMQDVVIAGGVES 118
EQ F ARN L + +P VT++R CGSS +A+ AA+AI++GM D I GGVE
Sbjct 61 TLEQGFNIARNAALLAGIPKQAGAVTVNRLCGSSMEAIHQAARAIMTGMGDTFIVGGVEH 120
Query 119 MSRAPMLSNASLHAKAGLPADPLSPRIKARFDVDQFSQFTG--AEMMAKKYGFDREQLDQ 176
M PM H GL +V + S G AEM+ K +G R+Q D+
Sbjct 121 MGHVPMNHGVDFH--PGLAT-----------NVAKASGMMGLTAEMLGKMHGITRQQQDE 167
Query 177 YALLSHQRAIQATETGNFENEIVVL---DVDGEAHRI--DEGIRFDANLESVSGLKPLVE 231
+A+ SHQRA AT G F NEI + D +G ++ DE IR + +LES++ L+P+ +
Sbjct 168 FAVRSHQRAHAATVEGRFANEIHAIEGHDANGALIKVMHDEVIRPETSLESLATLRPVFD 227
Query 232 --NGVVTAANASQICDGASAVLIVSERALKAYDLTPKARLIHMSVSAGDPVMMLEEPIFA 289
NG VTA +S + DGASA+L++ E KA L +AR+ M+V+ D +M P+ A
Sbjct 228 PANGTVTAGTSSALSDGASAMLVMEEEKAKALGLPIRARIRSMAVAGCDAAIMGYGPVPA 287
Query 290 TQKALKKAGLKITDIDLYEVNEAFAPVPLAWLQAL---DANPEALNIHGGAIALGHPLGA 346
TQKAL++AGL + DIDL E+NEAFA L ++ L D E +N++GGAIALGHPLG
Sbjct 288 TQKALQRAGLTMNDIDLIELNEAFAAQSLPCVKDLGLMDLVDEKVNLNGGAIALGHPLGC 347
Query 347 SGTKLMTTLIHALHTQGKRYGLQTMCEGGGMANVTILE 384
SG ++ TTLI+ + ++ GL TMC G G T+ E
Sbjct 348 SGARISTTLINLMESKDATLGLATMCIGLGQGIATVFE 385
>I6XHI4 Steroid 3-ketoacyl-CoA thiolase [Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv)]
Length=391
Score = 263 bits (672), Expect = 4e-88
Identities = 158/400 (40%), Positives = 236/400 (59%), Gaps = 27/400 (7%)
Query 1 MNVAYIVDAVRTAGGRRNGKLASWHPVDLGAEVINALLDRTGIDPNV----IDDAVFGCV 56
M IV+A R+ G+RNG L+ H +L V A++D+ GI + ++ + GCV
Sbjct 1 MGYPVIVEATRSPIGKRNGWLSGLHATELLGAVQKAVVDKAGIQSGLHAGDVEQVIGGCV 60
Query 57 TQAGEQTFAFARNIVLASKLPIHVPGVTIDRQCGSSQQAVQFAAQAILSGMQDVVIAGGV 116
TQ GEQ+ +R L + LP HV T+D QCGS QQA A I +G DV IA G+
Sbjct 61 TQFGEQSNNISRVAWLTAGLPEHVGATTVDCQCGSGQQANHLIAGLIAAGAIDVGIACGI 120
Query 117 ESMSRAPMLSNASLHAKAGLPADPLSPRIKAR-FDVDQFSQFTGAEMMAKKYGFDREQLD 175
E+MSR + +NA P I+A+ +D+D +QF AE +AK+ G RE +D
Sbjct 121 EAMSRVGLGANAG----------PDRSLIRAQSWDIDLPNQFEAAERIAKRRGITREDVD 170
Query 176 QYALLSHQRAIQATETGNFENEIV-----VLDVD----GEAHRI--DEGIRFDANLESVS 224
+ L S +RA +A G F+ EI VLD GE + D+G+R + + +
Sbjct 171 VFGLESQRRAQRAWAEGRFDREISPIQAPVLDEQNQPTGERRLVFRDQGLR-ETTMAGLG 229
Query 225 GLKPLVENGVVTAANASQICDGASAVLIVSERALKAYDLTPKARLIHMSVSAGDPVMMLE 284
LKP++E G+ TA +SQI DGA+AVL + E +A+ LTP+AR++ ++ +P L+
Sbjct 230 ELKPVLEGGIHTAGTSSQISDGAAAVLWMDEAVARAHGLTPRARIVAQALVGAEPYYHLD 289
Query 285 EPIFATQKALKKAGLKITDIDLYEVNEAFAPVPLAWLQALDANPEALNIHGGAIALGHPL 344
P+ +T K L+KAG+KI DID+ E+NEAFA V L+W + + + + +N++GGAIALGHP+
Sbjct 290 GPVQSTAKVLEKAGMKIGDIDIVEINEAFASVVLSWARVHEPDMDRVNVNGGAIALGHPV 349
Query 345 GASGTKLMTTLIHALHTQGKRYGLQTMCEGGGMANVTILE 384
G +G++L+TT +H L + L TMC GG ++ TI+E
Sbjct 350 GCTGSRLITTALHELERTDQSLALITMCAGGALSTGTIIE 389
>Q6DAP6 3-ketoacyl-CoA thiolase [Pectobacterium atrosepticum (strain
SCRI 1043 / ATCC BAA-672)]
Length=387
Score = 261 bits (668), Expect = 2e-87
Identities = 163/396 (41%), Positives = 226/396 (57%), Gaps = 23/396 (6%)
Query 1 MNVAYIVDAVRTAGGR-RNGKLASWHPVDLGAEVINALLDR-TGIDPNVIDDAVFGCVTQ 58
M IVDAVRT GR + G DL A ++ +LL R T +D IDD +GCV Q
Sbjct 1 MEKVVIVDAVRTPMGRSKGGAFRQVRAEDLSAHLMRSLLSRNTALDAREIDDIYWGCVQQ 60
Query 59 AGEQTFAFARNIVLASKLPIHVPGVTIDRQCGSSQQAVQFAAQAILSGMQDVVIAGGVES 118
A EQ F ARN L +++P+ VP T++R CGSS QA+ AA+AI+ G +V + GGVE
Sbjct 61 ALEQGFNVARNAALLAEIPVSVPATTVNRLCGSSMQALHDAARAIMVGDANVCLIGGVEH 120
Query 119 MSRAPMLSNASLHAKAGLPADPLSPRIKARFDVDQFSQFTGAEMMAKKYGFDREQLDQYA 178
M PM H P + AEM+A+ + RE DQ+A
Sbjct 121 MGHVPMNHGVDFH-----------PGLSRTIAKAAGMMGLTAEMLARMHNISREMQDQFA 169
Query 179 LLSHQRAIQATETGNFENEIVVL---DVDGEAHRI--DEGIRFDANLESVSGLKPLVE-- 231
SHQRA AT++G F +EIV D DG R DE IR D ++S++ LKP +
Sbjct 170 ARSHQRAYHATQSGAFRHEIVPTAGHDADGALQRFDYDEVIRPDTTIDSLAALKPAFDPV 229
Query 232 NGVVTAANASQICDGASAVLIVSERALKAYDLTPKARLIHMSVSAGDPVMMLEEPIFATQ 291
NG VTA ++S + DGASA+LI+SE + L +AR+ M+V DP +M P+ AT+
Sbjct 230 NGTVTAGSSSALSDGASAMLIMSESRAASLGLPVRARIRAMAVVGCDPSIMGYGPVPATK 289
Query 292 KALKKAGLKITDIDLYEVNEAFAPVPLAWLQ---ALDANPEALNIHGGAIALGHPLGASG 348
ALK+AGL + DI ++E+NEAFA L ++ L+ E +N++GGAIALGHPLG SG
Sbjct 290 LALKRAGLSLADIGIFELNEAFAAQTLPCIKDLGLLEQLDEKVNLNGGAIALGHPLGCSG 349
Query 349 TKLMTTLIHALHTQGKRYGLQTMCEGGGMANVTILE 384
++ TTLI+ + ++ ++G+ TMC G G T+ E
Sbjct 350 ARISTTLINLMESRDAQFGVATMCIGLGQGIATVFE 385
>Q7MZ91 3-ketoacyl-CoA thiolase [Photorhabdus laumondii subsp.
laumondii (strain DSM 15139 / CIP 105565 / TT01)]
Length=388
Score = 261 bits (668), Expect = 2e-87
Identities = 167/398 (42%), Positives = 226/398 (57%), Gaps = 27/398 (7%)
Query 1 MNVAYIVDAVRTAGGR-RNGKLASWHPVDLGAEVINALLDRT-GIDPNVIDDAVFGCVTQ 58
M I+D +RT GR + G DL A ++ L R I + IDD +GCV Q
Sbjct 1 MENVVIIDGIRTPMGRSKGGAFRQVRAEDLSAHLMKKLFKRNPAIQQHEIDDIYWGCVQQ 60
Query 59 AGEQTFAFARNIVLASKLPIHVPGVTIDRQCGSSQQAVQFAAQAILSGMQDVVIAGGVES 118
EQ F ARN L + +P VP VT++R CGSS QA+ A+ I++G +V + GGVE
Sbjct 61 TLEQGFNIARNAALLADIPHSVPAVTVNRLCGSSMQALHDGARMIMTGEANVTLIGGVEH 120
Query 119 MSRAPMLSNASLHAKAGLPADPLSPRIKARFDVDQFSQFTG--AEMMAKKYGFDREQLDQ 176
M PM H K L V + + G AEM+AK + RE D+
Sbjct 121 MGHVPMTHGVDFHPKMSL-------------SVAKAAGVMGLTAEMLAKIHHISREMQDE 167
Query 177 YALLSHQRAIQATETGNFENEIVVL---DVDGEAHRI--DEGIRFDANLESVSGLKPLVE 231
+AL SHQRA QAT++G F NEI + D DG R DE IR DANL+ ++ L+P+ +
Sbjct 168 FALRSHQRATQATQSGAFANEISPIYGHDADGILKRFDYDEVIRSDANLKDLAALRPVFD 227
Query 232 --NGVVTAANASQICDGASAVLIVSERALKAYDLTPKARLIHMSVSAGDPVMMLEEPIFA 289
G VTA ++S + DGASA+LI SE K L P+AR+ M+ DP +M P+ A
Sbjct 228 PVTGSVTAGSSSALSDGASAMLITSESYAKNLGLKPRARIRSMAAVGCDPSIMGYGPVPA 287
Query 290 TQKALKKAGLKITDIDLYEVNEAFAPVPLAWLQA---LDANPEALNIHGGAIALGHPLGA 346
TQ ALKKAGL + DI + E+NEAFA LA L+ LD+ + +N++GGAIALGHPLG
Sbjct 288 TQMALKKAGLVLGDIGVIELNEAFAAQSLACLKGLNLLDSMDDKVNLNGGAIALGHPLGC 347
Query 347 SGTKLMTTLIHALHTQGKRYGLQTMCEGGGMANVTILE 384
SG ++ TTL++ + + ++GL TMC G G TI+E
Sbjct 348 SGARITTTLLNLMERRDVQFGLATMCIGLGQGIATIIE 385
>A1S1I7 3-ketoacyl-CoA thiolase [Shewanella amazonensis (strain
ATCC BAA-1098 / SB2B)]
Length=387
Score = 261 bits (667), Expect = 2e-87
Identities = 167/398 (42%), Positives = 232/398 (58%), Gaps = 27/398 (7%)
Query 1 MNVAYIVDAVRTAGGR-RNGKLASWHPVDLGAEVINALLDRT-GIDPNVIDDAVFGCVTQ 58
M A IVD +RT GR + G + L AE++ ALL R G+DPN I+D ++GCV Q
Sbjct 1 MKQAVIVDCIRTPMGRSKGGVFRNVRAETLSAELMKALLLRNPGVDPNTIEDVIWGCVQQ 60
Query 59 AGEQTFAFARNIVLASKLPIHVPGVTIDRQCGSSQQAVQFAAQAILSGMQDVVIAGGVES 118
EQ F ARN L + +P VT++R CGSS +A+ A++AI++GM D I GGVE
Sbjct 61 TLEQGFNIARNASLLAGVPKTAGAVTVNRLCGSSMEALHQASRAIMTGMGDTFIIGGVEH 120
Query 119 MSRAPMLSNASLHAKAGLPADPLSPRIKARFDVDQFSQFTG--AEMMAKKYGFDREQLDQ 176
M PM H GL A +V + S G AEM+ K +G RE DQ
Sbjct 121 MGHVPMNHGVDFH--PGLAA-----------NVAKASGMMGLTAEMLGKLHGISREMQDQ 167
Query 177 YALLSHQRAIQATETGNFENEIVVL---DVDGEAHRI--DEGIRFDANLESVSGLKPLVE 231
+A+ SHQRA A+ G F NEI + D +G ++ DE IR + LES++GL+P+ +
Sbjct 168 FAVRSHQRAHAASIEGRFANEIYAIEGHDANGALIKVDYDEVIRPETTLESLAGLRPVFD 227
Query 232 --NGVVTAANASQICDGASAVLIVSERALKAYDLTPKARLIHMSVSAGDPVMMLEEPIFA 289
NG VTA +S + DGA+A+L++ E +A LT +AR+ M+V+ D +M P+ A
Sbjct 228 PANGTVTAGTSSALSDGAAAMLVMEEEKARALGLTIRARVRSMAVAGCDAAIMGYGPVPA 287
Query 290 TQKALKKAGLKITDIDLYEVNEAFAPVPLAWLQAL---DANPEALNIHGGAIALGHPLGA 346
TQKAL +AGL I D+D+ E+NEAFA L ++ L D + +N++GGAIALGHPLG
Sbjct 288 TQKALARAGLSIQDMDVIELNEAFAAQSLPCVKDLGLMDVVEDKVNLNGGAIALGHPLGC 347
Query 347 SGTKLMTTLIHALHTQGKRYGLQTMCEGGGMANVTILE 384
SG ++ TTLI+ + + GL TMC G G T+ E
Sbjct 348 SGARISTTLINLMEHKDATLGLATMCIGLGQGIATVFE 385
>Q5QXH8 3-ketoacyl-CoA thiolase [Idiomarina loihiensis (strain
ATCC BAA-735 / DSM 15497 / L2-TR)]
Length=387
Score = 259 bits (663), Expect = 9e-87
Identities = 158/391 (40%), Positives = 225/391 (58%), Gaps = 23/391 (6%)
Query 6 IVDAVRTAGGR-RNGKLASWHPVDLGAEVINALLDRTG-IDPNVIDDAVFGCVTQAGEQT 63
IVD +RT GR +NG DL A ++ LL+R +DP ++D +GCV Q EQ
Sbjct 6 IVDCIRTPMGRSKNGVFRHTRAEDLSAALMKGLLERNPEVDPEELEDIYWGCVQQTLEQG 65
Query 64 FAFARNIVLASKLPIHVPGVTIDRQCGSSQQAVQFAAQAILSGMQDVVIAGGVESMSRAP 123
F ARN L + +P V GVT++R CGSS QA+ A +AI++G D+ +AGGVE M P
Sbjct 66 FNIARNSALIAGIPHKVAGVTVNRLCGSSMQALHDATRAIMNGDGDIFMAGGVEHMGHVP 125
Query 124 MLSNASLHAKAGLPADPLSPRIKARFDVDQFSQFTGAEMMAKKYGFDREQLDQYALLSHQ 183
M H P + S AE++++K+G REQ D++ SH+
Sbjct 126 MTHGIDFH-----------PGMNKSVAKASGSMGMTAELLSRKFGITREQQDEFGARSHR 174
Query 184 RAIQATETGNFENEIVVL---DVDGEAHRI--DEGIRFDANLESVSGLKPLVE--NGVVT 236
+A +AT G F EI + + DGE R+ DE IR + E +S L+P+ + NG VT
Sbjct 175 KAHEATVEGRFAKEIYAMNGHNADGELVRVTEDEVIRPETTAEGLSQLRPVFDPANGTVT 234
Query 237 AANASQICDGASAVLIVSERALKAYDLTPKARLIHMSVSAGDPVMMLEEPIFATQKALKK 296
A +S + DGA+A+L++S K LTP+ ++ M+V+ DP +M P+ AT+KALK+
Sbjct 235 AGTSSALSDGAAAMLVMSADKAKELGLTPRVKIRSMAVAGCDPSIMGYGPVPATEKALKR 294
Query 297 AGLKITDIDLYEVNEAFAPVPLAWLQAL---DANPEALNIHGGAIALGHPLGASGTKLMT 353
AG+ I DID+ E+NEAFA L L+ L D E +N++GGAIALGHPLG SG ++ T
Sbjct 295 AGVSIDDIDVVELNEAFAAQSLPVLKGLKLFDKMEEKVNLNGGAIALGHPLGCSGARIST 354
Query 354 TLIHALHTQGKRYGLQTMCEGGGMANVTILE 384
TLI+ + + + GL TMC G G T+ E
Sbjct 355 TLINLMEEKDAKLGLATMCIGLGQGIATVFE 385
>A4TR28 3-ketoacyl-CoA thiolase [Yersinia pestis (strain Pestoides
F)]
Length=387
Score = 258 bits (660), Expect = 2e-86
Identities = 160/396 (40%), Positives = 226/396 (57%), Gaps = 23/396 (6%)
Query 1 MNVAYIVDAVRTAGGR-RNGKLASWHPVDLGAEVINALLDRT-GIDPNVIDDAVFGCVTQ 58
M I+DAVRT GR + G DL A ++ A++ R G++ IDD +GCV Q
Sbjct 1 MENVVIIDAVRTPMGRSKGGAFRHVRAEDLSAHLMRAVISRNPGLNAAEIDDIYWGCVQQ 60
Query 59 AGEQTFAFARNIVLASKLPIHVPGVTIDRQCGSSQQAVQFAAQAILSGMQDVVIAGGVES 118
EQ F ARN L +++P VP VT++R CGSS QA+ A+AI+ G + + GGVE
Sbjct 61 TLEQGFNIARNASLLAEIPHSVPAVTVNRLCGSSMQALHDGARAIMVGDAKISLIGGVEH 120
Query 119 MSRAPMLSNASLHAKAGLPADPLSPRIKARFDVDQFSQFTGAEMMAKKYGFDREQLDQYA 178
M PM H G + + AEM+AK + R+ D++A
Sbjct 121 MGHVPMNHGVDFHPGMGRTVAKAAGMMGLT-----------AEMLAKIHNISRQSQDEFA 169
Query 179 LLSHQRAIQATETGNFENEIVVL---DVDGEAHRID--EGIRFDANLESVSGLKPLVE-- 231
SHQRA AT+ G+F EIV D +G R D E IR + NL ++ L+P +
Sbjct 170 FRSHQRAYAATQAGHFAKEIVATNGHDAEGVLKRFDFDEVIRPETNLSGLAALRPAFDPV 229
Query 232 NGVVTAANASQICDGASAVLIVSERALKAYDLTPKARLIHMSVSAGDPVMMLEEPIFATQ 291
NG VTA +S + DGASA+LI+SE K+ LTP+AR+ M+V DP +M P+ A+Q
Sbjct 230 NGTVTAGTSSALSDGASAMLIMSESRAKSLGLTPRARIRSMAVVGCDPSIMGYGPVPASQ 289
Query 292 KALKKAGLKITDIDLYEVNEAFAPVPLAWLQA---LDANPEALNIHGGAIALGHPLGASG 348
ALK+AGL++ DI L+E+NEAFA LA L+ L++ + +N++GGAIALGHPLG SG
Sbjct 290 LALKRAGLELADIGLFELNEAFAAQSLACLKGLGLLESMDDKVNLNGGAIALGHPLGCSG 349
Query 349 TKLMTTLIHALHTQGKRYGLQTMCEGGGMANVTILE 384
++ TTL++ + + ++GL TMC G G T+ E
Sbjct 350 ARISTTLLNLMERRDVQFGLATMCIGLGQGIATVFE 385
>Q1CNA0 3-ketoacyl-CoA thiolase [Yersinia pestis bv. Antiqua (strain
Nepal516)]
Length=387
Score = 258 bits (660), Expect = 2e-86
Identities = 160/396 (40%), Positives = 226/396 (57%), Gaps = 23/396 (6%)
Query 1 MNVAYIVDAVRTAGGR-RNGKLASWHPVDLGAEVINALLDRT-GIDPNVIDDAVFGCVTQ 58
M I+DAVRT GR + G DL A ++ A++ R G++ IDD +GCV Q
Sbjct 1 MENVVIIDAVRTPMGRSKGGAFRHVRAEDLSAHLMRAVISRNPGLNAAEIDDIYWGCVQQ 60
Query 59 AGEQTFAFARNIVLASKLPIHVPGVTIDRQCGSSQQAVQFAAQAILSGMQDVVIAGGVES 118
EQ F ARN L +++P VP VT++R CGSS QA+ A+AI+ G + + GGVE
Sbjct 61 TLEQGFNIARNASLLAEIPHSVPAVTVNRLCGSSMQALHDGARAIMVGDAKISLIGGVEH 120
Query 119 MSRAPMLSNASLHAKAGLPADPLSPRIKARFDVDQFSQFTGAEMMAKKYGFDREQLDQYA 178
M PM H G + + AEM+AK + R+ D++A
Sbjct 121 MGHVPMNHGVDFHPGMGRTVAKAAGMMGLT-----------AEMLAKIHNISRQSQDEFA 169
Query 179 LLSHQRAIQATETGNFENEIVVL---DVDGEAHRID--EGIRFDANLESVSGLKPLVE-- 231
SHQRA AT+ G+F EIV D +G R D E IR + NL ++ L+P +
Sbjct 170 FRSHQRAYAATQAGHFAKEIVATNGHDAEGVLKRFDFDEVIRPETNLSGLAALRPAFDPV 229
Query 232 NGVVTAANASQICDGASAVLIVSERALKAYDLTPKARLIHMSVSAGDPVMMLEEPIFATQ 291
NG VTA +S + DGASA+LI+SE K+ LTP+AR+ M+V DP +M P+ A+Q
Sbjct 230 NGTVTAGTSSALSDGASAMLIMSESRAKSLGLTPRARIRSMAVVGCDPSIMGYGPVPASQ 289
Query 292 KALKKAGLKITDIDLYEVNEAFAPVPLAWLQA---LDANPEALNIHGGAIALGHPLGASG 348
ALK+AGL++ DI L+E+NEAFA LA L+ L++ + +N++GGAIALGHPLG SG
Sbjct 290 LALKRAGLELADIGLFELNEAFAAQSLACLKGLGLLESMDDKVNLNGGAIALGHPLGCSG 349
Query 349 TKLMTTLIHALHTQGKRYGLQTMCEGGGMANVTILE 384
++ TTL++ + + ++GL TMC G G T+ E
Sbjct 350 ARISTTLLNLMERRDVQFGLATMCIGLGQGIATVFE 385
>Q8ZAM9 3-ketoacyl-CoA thiolase [Yersinia pestis]
Length=387
Score = 258 bits (660), Expect = 2e-86
Identities = 160/396 (40%), Positives = 226/396 (57%), Gaps = 23/396 (6%)
Query 1 MNVAYIVDAVRTAGGR-RNGKLASWHPVDLGAEVINALLDRT-GIDPNVIDDAVFGCVTQ 58
M I+DAVRT GR + G DL A ++ A++ R G++ IDD +GCV Q
Sbjct 1 MENVVIIDAVRTPMGRSKGGAFRHVRAEDLSAHLMRAVISRNPGLNAAEIDDIYWGCVQQ 60
Query 59 AGEQTFAFARNIVLASKLPIHVPGVTIDRQCGSSQQAVQFAAQAILSGMQDVVIAGGVES 118
EQ F ARN L +++P VP VT++R CGSS QA+ A+AI+ G + + GGVE
Sbjct 61 TLEQGFNIARNASLLAEIPHSVPAVTVNRLCGSSMQALHDGARAIMVGDAKISLIGGVEH 120
Query 119 MSRAPMLSNASLHAKAGLPADPLSPRIKARFDVDQFSQFTGAEMMAKKYGFDREQLDQYA 178
M PM H G + + AEM+AK + R+ D++A
Sbjct 121 MGHVPMNHGVDFHPGMGRTVAKAAGMMGLT-----------AEMLAKIHNISRQSQDEFA 169
Query 179 LLSHQRAIQATETGNFENEIVVL---DVDGEAHRID--EGIRFDANLESVSGLKPLVE-- 231
SHQRA AT+ G+F EIV D +G R D E IR + NL ++ L+P +
Sbjct 170 FRSHQRAYAATQAGHFAKEIVATNGHDAEGVLKRFDFDEVIRPETNLSGLAALRPAFDPV 229
Query 232 NGVVTAANASQICDGASAVLIVSERALKAYDLTPKARLIHMSVSAGDPVMMLEEPIFATQ 291
NG VTA +S + DGASA+LI+SE K+ LTP+AR+ M+V DP +M P+ A+Q
Sbjct 230 NGTVTAGTSSALSDGASAMLIMSESRAKSLGLTPRARIRSMAVVGCDPSIMGYGPVPASQ 289
Query 292 KALKKAGLKITDIDLYEVNEAFAPVPLAWLQA---LDANPEALNIHGGAIALGHPLGASG 348
ALK+AGL++ DI L+E+NEAFA LA L+ L++ + +N++GGAIALGHPLG SG
Sbjct 290 LALKRAGLELADIGLFELNEAFAAQSLACLKGLGLLESMDDKVNLNGGAIALGHPLGCSG 349
Query 349 TKLMTTLIHALHTQGKRYGLQTMCEGGGMANVTILE 384
++ TTL++ + + ++GL TMC G G T+ E
Sbjct 350 ARISTTLLNLMERRDVQFGLATMCIGLGQGIATVFE 385
>Q1C2C3 3-ketoacyl-CoA thiolase [Yersinia pestis bv. Antiqua (strain
Antiqua)]
Length=387
Score = 258 bits (660), Expect = 2e-86
Identities = 160/396 (40%), Positives = 226/396 (57%), Gaps = 23/396 (6%)
Query 1 MNVAYIVDAVRTAGGR-RNGKLASWHPVDLGAEVINALLDRT-GIDPNVIDDAVFGCVTQ 58
M I+DAVRT GR + G DL A ++ A++ R G++ IDD +GCV Q
Sbjct 1 MENVVIIDAVRTPMGRSKGGAFRHVRAEDLSAHLMRAVISRNPGLNAAEIDDIYWGCVQQ 60
Query 59 AGEQTFAFARNIVLASKLPIHVPGVTIDRQCGSSQQAVQFAAQAILSGMQDVVIAGGVES 118
EQ F ARN L +++P VP VT++R CGSS QA+ A+AI+ G + + GGVE
Sbjct 61 TLEQGFNIARNASLLAEIPHSVPAVTVNRLCGSSMQALHDGARAIMVGDAKISLIGGVEH 120
Query 119 MSRAPMLSNASLHAKAGLPADPLSPRIKARFDVDQFSQFTGAEMMAKKYGFDREQLDQYA 178
M PM H G + + AEM+AK + R+ D++A
Sbjct 121 MGHVPMNHGVDFHPGMGRTVAKAAGMMGLT-----------AEMLAKIHNISRQSQDEFA 169
Query 179 LLSHQRAIQATETGNFENEIVVL---DVDGEAHRID--EGIRFDANLESVSGLKPLVE-- 231
SHQRA AT+ G+F EIV D +G R D E IR + NL ++ L+P +
Sbjct 170 FRSHQRAYAATQAGHFAKEIVATNGHDAEGVLKRFDFDEVIRPETNLSGLAALRPAFDPV 229
Query 232 NGVVTAANASQICDGASAVLIVSERALKAYDLTPKARLIHMSVSAGDPVMMLEEPIFATQ 291
NG VTA +S + DGASA+LI+SE K+ LTP+AR+ M+V DP +M P+ A+Q
Sbjct 230 NGTVTAGTSSALSDGASAMLIMSESRAKSLGLTPRARIRSMAVVGCDPSIMGYGPVPASQ 289
Query 292 KALKKAGLKITDIDLYEVNEAFAPVPLAWLQA---LDANPEALNIHGGAIALGHPLGASG 348
ALK+AGL++ DI L+E+NEAFA LA L+ L++ + +N++GGAIALGHPLG SG
Sbjct 290 LALKRAGLELADIGLFELNEAFAAQSLACLKGLGLLESMDDKVNLNGGAIALGHPLGCSG 349
Query 349 TKLMTTLIHALHTQGKRYGLQTMCEGGGMANVTILE 384
++ TTL++ + + ++GL TMC G G T+ E
Sbjct 350 ARISTTLLNLMERRDVQFGLATMCIGLGQGIATVFE 385
>A7FDF1 3-ketoacyl-CoA thiolase [Yersinia pseudotuberculosis serotype
O:1b (strain IP 31758)]
Length=387
Score = 258 bits (660), Expect = 2e-86
Identities = 160/396 (40%), Positives = 226/396 (57%), Gaps = 23/396 (6%)
Query 1 MNVAYIVDAVRTAGGR-RNGKLASWHPVDLGAEVINALLDRT-GIDPNVIDDAVFGCVTQ 58
M I+DAVRT GR + G DL A ++ A++ R G++ IDD +GCV Q
Sbjct 1 MENVVIIDAVRTPMGRSKGGAFRHVRAEDLSAHLMRAVISRNPGLNAAEIDDIYWGCVQQ 60
Query 59 AGEQTFAFARNIVLASKLPIHVPGVTIDRQCGSSQQAVQFAAQAILSGMQDVVIAGGVES 118
EQ F ARN L +++P VP VT++R CGSS QA+ A+AI+ G + + GGVE
Sbjct 61 TLEQGFNIARNASLLAEIPHSVPAVTVNRLCGSSMQALHDGARAIMVGDAKISLIGGVEH 120
Query 119 MSRAPMLSNASLHAKAGLPADPLSPRIKARFDVDQFSQFTGAEMMAKKYGFDREQLDQYA 178
M PM H G + + AEM+AK + R+ D++A
Sbjct 121 MGHVPMNHGVDFHPGMGRTVAKAAGMMGLT-----------AEMLAKIHNISRQSQDEFA 169
Query 179 LLSHQRAIQATETGNFENEIVVL---DVDGEAHRID--EGIRFDANLESVSGLKPLVE-- 231
SHQRA AT+ G+F EIV D +G R D E IR + NL ++ L+P +
Sbjct 170 FRSHQRAYAATQAGHFAKEIVATNGHDAEGVLKRFDFDEVIRPETNLSGLAALRPAFDPV 229
Query 232 NGVVTAANASQICDGASAVLIVSERALKAYDLTPKARLIHMSVSAGDPVMMLEEPIFATQ 291
NG VTA +S + DGASA+LI+SE K+ LTP+AR+ M+V DP +M P+ A+Q
Sbjct 230 NGTVTAGTSSALSDGASAMLIMSESRAKSLGLTPRARIRSMAVVGCDPSIMGYGPVPASQ 289
Query 292 KALKKAGLKITDIDLYEVNEAFAPVPLAWLQA---LDANPEALNIHGGAIALGHPLGASG 348
ALK+AGL++ DI L+E+NEAFA LA L+ L++ + +N++GGAIALGHPLG SG
Sbjct 290 LALKRAGLELADIGLFELNEAFAAQSLACLKGLGLLESMDDKVNLNGGAIALGHPLGCSG 349
Query 349 TKLMTTLIHALHTQGKRYGLQTMCEGGGMANVTILE 384
++ TTL++ + + ++GL TMC G G T+ E
Sbjct 350 ARISTTLLNLMERRDVQFGLATMCIGLGQGIATVFE 385
>A1TZR8 3-ketoacyl-CoA thiolase [Marinobacter nauticus (strain
ATCC 700491 / DSM 11845 / VT8)]
Length=391
Score = 258 bits (660), Expect = 3e-86
Identities = 161/394 (41%), Positives = 230/394 (58%), Gaps = 29/394 (7%)
Query 6 IVDAVRTAGGR-RNGKLASWHPVDLGAEVINALLDRTG-IDPNVIDDAVFGCVTQAGEQT 63
+VD VRT GR +NG + L A +I AL +R +DP ++D ++GCV Q EQ
Sbjct 10 VVDCVRTPMGRAKNGCFRNVRAETLSAALIEALFERNPKLDPKEVEDVIWGCVNQTKEQG 69
Query 64 FAFARNIVLASKLPIHVPGVTIDRQCGSSQQAVQFAAQAILSGMQDVVIAGGVESMSRAP 123
F AR I L +++P T++R CGS+ A+ AAQAI +G DV + GGVE M P
Sbjct 70 FNVARQISLLTRIPHESAAQTVNRLCGSAMSAIHTAAQAIQTGNGDVFLVGGVEHMGHVP 129
Query 124 MLSNASLHAKAGLPADPLSPRIKARFDVDQFSQFTG--AEMMAKKYGFDREQLDQYALLS 181
M G +P + + A+ S G AEM+AK +G REQ D++ S
Sbjct 130 MTE--------GFDHNPAASKYSAKA-----SNMMGLTAEMLAKMHGITREQQDEFGARS 176
Query 182 HQRAIQATETGNFENEIVVLDVDGEAHRI-----DEGIRFDANLESVSGLKPLVE--NGV 234
H+ A +AT+ G F+NEIV ++ E + DE IR + ES+ L+P + NG
Sbjct 177 HRLAHEATQEGRFKNEIVPIEGHDENGFVKLIEEDETIRPETTAESLGQLRPAFDPKNGT 236
Query 235 VTAANASQICDGASAVLIVSERALKAYDLTPKARLIHMSVSAGDPVMMLEEPIFATQKAL 294
VTA +SQ+ DGASA++++S +A LTP A++ M+V+ DP +M P+ AT+KAL
Sbjct 237 VTAGTSSQLTDGASAMVLMSAERAEALGLTPIAKIRSMAVAGCDPAIMGYGPVPATKKAL 296
Query 295 KKAGLKITDIDLYEVNEAFA----PVPLAWLQALDANPEALNIHGGAIALGHPLGASGTK 350
K+AGLK+ DID +E+NEAFA PV L L+ L E +N++GGAIALGHPLG SG +
Sbjct 297 KRAGLKVEDIDFWELNEAFAGQSLPV-LKDLKLLGVMEEKVNLNGGAIALGHPLGCSGAR 355
Query 351 LMTTLIHALHTQGKRYGLQTMCEGGGMANVTILE 384
+ TTL++ + +G + G+ TMC G G T+ E
Sbjct 356 ISTTLLNIMQAKGGKLGVSTMCIGLGQGIATVWE 389
>O32177 3-ketoacyl-CoA thiolase [Bacillus subtilis (strain 168)]
Length=391
Score = 255 bits (652), Expect = 4e-85
Identities = 154/403 (38%), Positives = 219/403 (54%), Gaps = 29/403 (7%)
Query 1 MNVAYIVDAVRTAGGR-RNGKLASWHPVDLGAEVINALLDRTGIDPNVIDDAVFGCVTQA 59
M A IV RT G+ + G LA+ P DLGA + L R G IDD + GC T
Sbjct 1 MKEAVIVSGARTPVGKAKKGSLATVRPDDLGAICVKETLKRAGGYEGNIDDLIIGCATPE 60
Query 60 GEQTFAFARNIVLASKLPIHVPGVTIDRQCGSSQQAVQFAAQAILSGMQDVVIAGGVESM 119
EQ ARNI + LP VP +T++R C S Q++ +AA+ I+ G D IAGG ESM
Sbjct 61 AEQGLNMARNIGALAGLPYTVPAITVNRYCSSGLQSIAYAAEKIMLGAYDTAIAGGAESM 120
Query 120 SRAPMLSNASLHAKAGLPADPLSPRIKARFDVDQFSQFTG--AEMMAKKYGFDREQLDQY 177
S+ PM+ + + P + ++ G AE +AKKYG RE D +
Sbjct 121 SQVPMMGHVT------------RPNLALAEKAPEYYMSMGHTAEQVAKKYGVSREDQDAF 168
Query 178 ALLSHQRAIQATETGNFENEIVVLDVD----GEAHRI---------DEGIRFDANLESVS 224
A+ SHQ A +A G F++EIV ++V GE H+ DEG+R + +S
Sbjct 169 AVRSHQNAAKALAEGKFKDEIVPVEVTVTEIGEDHKPMEKQFVFSQDEGVRPQTTADILS 228
Query 225 GLKPLVE-NGVVTAANASQICDGASAVLIVSERALKAYDLTPKARLIHMSVSAGDPVMML 283
L+P +G VTA N+SQ DGA+AV+++ A L P + +V P +M
Sbjct 229 TLRPAFSVDGTVTAGNSSQTSDGAAAVMLMDREKADALGLAPLVKFRSFAVGGVPPEVMG 288
Query 284 EEPIFATQKALKKAGLKITDIDLYEVNEAFAPVPLAWLQALDANPEALNIHGGAIALGHP 343
P+ A +ALK AGL++ DI L+E+NEAFA + ++ L + E +N++GGAIALGHP
Sbjct 289 IGPVEAIPRALKLAGLQLQDIGLFELNEAFASQAIQVIRELGIDEEKVNVNGGAIALGHP 348
Query 344 LGASGTKLMTTLIHALHTQGKRYGLQTMCEGGGMANVTILEAC 386
LG +GTKL +LIH + + +++G+ TMC GGGM + E C
Sbjct 349 LGCTGTKLTLSLIHEMKRRNEQFGVVTMCIGGGMGAAGVFELC 391
>Q9F0Y6 3-ketoacyl-CoA thiolase [Enterobacter cloacae]
Length=387
Score = 248 bits (634), Expect = 2e-82
Identities = 156/396 (39%), Positives = 223/396 (56%), Gaps = 23/396 (6%)
Query 1 MNVAYIVDAVRTAGGR-RNGKLASWHPVDLGAEVINALLDRT-GIDPNVIDDAVFGCVTQ 58
M IVDA+RT GR + G + DL A ++ +LL R +DP +DD +GC+ Q
Sbjct 1 MEKVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPALDPAALDDIYWGCLHQ 60
Query 59 AGEQTFAFARNIVLASKLPIHVPGVTIDRQCGSSQQAVQFAAQAILSGMQDVVIAGGVES 118
EQ F ARN L +++P VP VT++R CGSS QA+ AA+ I++G + GGVE
Sbjct 61 TLEQGFNLARNASLLAEIPHSVPAVTVNRLCGSSMQALHDAARMIMTGDAQACLVGGVEH 120
Query 119 MSRAPMLSNASLHAKAGLPADPLSPRIKARFDVDQFSQFTGAEMMAKKYGFDREQLDQYA 178
M PM H P + AEM+++ +G RE D +A
Sbjct 121 MGHVPMSHGVHFH-----------PGMSRNVAKAAGMMGLTAEMLSRLHGISREMQDAFA 169
Query 179 LLSHQRAIQATETGNFENEIVVL---DVDGEAHRI--DEGIRFDANLESVSGLKPLVE-- 231
SH RA AT++G F+NEI+ D DG + DE IR + +E++S L+P +
Sbjct 170 ARSHARAWAATQSGAFKNEIIPTGGHDADGVLKQFSYDEVIRPETTVEALSTLRPAFDPV 229
Query 232 NGVVTAANASQICDGASAVLIVSERALKAYDLTPKARLIHMSVSAGDPVMMLEEPIFATQ 291
G VTA +S + DGA+A+L++SE + LTP+AR+ M+V DP +M P+ A++
Sbjct 230 TGTVTAGTSSALSDGAAAMLVMSESRARELGLTPRARVRSMAVVGCDPSIMGYGPVPASK 289
Query 292 KALKKAGLKITDIDLYEVNEAFAPVPLAWLQALDAN---PEALNIHGGAIALGHPLGASG 348
ALKKAGL +DIDL+E+NEAFA L ++ L E +N++GGAIALGHPLG SG
Sbjct 290 LALKKAGLTASDIDLFEMNEAFAAQILPCIKDLGLMGQIDEKINLNGGAIALGHPLGCSG 349
Query 349 TKLMTTLIHALHTQGKRYGLQTMCEGGGMANVTILE 384
++ TTLI+ + + ++GL TMC G G T+ E
Sbjct 350 ARISTTLINLMEGKDAQFGLATMCIGLGQGIATVFE 385
>P0C7L2 3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA thiolase
[Escherichia coli (strain K12)]
Length=401
Score = 247 bits (631), Expect = 8e-82
Identities = 164/401 (41%), Positives = 224/401 (56%), Gaps = 19/401 (5%)
Query 1 MNVAYIVDAVRTAGGRRNGKLASWHPVDLGAEVINALLDRTG-IDPNVIDDAVFGCVTQA 59
M A+I D +RT GR G L+S DL A + LL R +D IDD + GC QA
Sbjct 1 MREAFICDGIRTPIGRYGGALSSVRADDLAAIPLRELLVRNPRLDAECIDDVILGCANQA 60
Query 60 GEQTFAFARNIVLASKLPIHVPGVTIDRQCGSSQQAVQFAAQAILSGMQDVVIAGGVESM 119
GE AR L + LP V G TI+R CGS A+ FAA+AI +G D++IAGGVESM
Sbjct 61 GEDNRNVARMATLLAGLPQSVSGTTINRLCGSGLDALGFAARAIKAGDGDLLIAGGVESM 120
Query 120 SRAPMLSN--ASLHAKAGLPADP------LSPRIKARFDVDQFSQFTGAEMMAKKYGFDR 171
SRAP + AS ++ D ++P + +F D + AE +A+ R
Sbjct 121 SRAPFVMGKAASAFSRQAEMFDTTIGWRFVNPLMAQQFGTDSMPET--AENVAELLKISR 178
Query 172 EQLDQYALLSHQRAIQATETGNFENEIVVLDVDGEAHRI-----DEGIRFDANLESVSGL 226
E D +AL S QR +A +G EIV + + + + DE +R + LE + GL
Sbjct 179 EDQDSFALRSQQRTAKAQSSGILAEEIVPVVLKNKKGVVTEIQHDEHLRPETTLEQLRGL 238
Query 227 K-PLVENGVVTAANASQICDGASAVLIVSERALKAYDLTPKARLIHMSVSAGDPVMMLEE 285
K P NGV+TA NAS + DGA+A++I SE+ A LTP+AR++ M+ + +P +M
Sbjct 239 KAPFRANGVITAGNASGVNDGAAALIIASEQMAAAQGLTPRARIVAMATAGVEPRLMGLG 298
Query 286 PIFATQKALKKAGLKITDIDLYEVNEAFAPVPLAWLQALDANPEA--LNIHGGAIALGHP 343
P+ AT++ L++AGL I D+D+ E+NEAFA L L+ L +A +N +GGAIALGHP
Sbjct 299 PVPATRRVLERAGLSIHDMDVIELNEAFAAQALGVLRELGLPDDAPHVNPNGGAIALGHP 358
Query 344 LGASGTKLMTTLIHALHTQGKRYGLQTMCEGGGMANVTILE 384
LG SG +L H LH + RY L TMC G G ILE
Sbjct 359 LGMSGARLALAASHELHRRNGRYALCTMCIGVGQGIAMILE 399
>Q43935 Beta-ketoadipyl-CoA thiolase [Acinetobacter baylyi (strain
ATCC 33305 / BD413 / ADP1)]
Length=401
Score = 246 bits (629), Expect = 2e-81
Identities = 167/401 (42%), Positives = 230/401 (57%), Gaps = 19/401 (5%)
Query 1 MNVAYIVDAVRTAGGRRNGKLASWHPVDLGAEVINALLDRT-GIDPNVIDDAVFGCVTQA 59
M AYIVDA+RT GR G LA+ DLGA I AL++R ++ +DD ++GC QA
Sbjct 1 MKHAYIVDAIRTPFGRYAGGLAAVRADDLGAIPIAALIERNPSVNWAQVDDVIYGCANQA 60
Query 60 GEQTFAFARNIVLASKLPIHVPGVTIDRQCGSSQQAVQFAAQAILSGMQDVVIAGGVESM 119
GE R L + LP+ VP T++R CGSS A+ AA+AI +G ++IAGGVESM
Sbjct 61 GEDNRNVGRMSALLAGLPVEVPATTVNRLCGSSLDAIAMAARAIKAGEAHLIIAGGVESM 120
Query 120 SRAPMLSNASLHA--------KAGLPADPLSPRIKARFDVDQFSQFTGAEMMAKKYGFDR 171
SRAP + S A + ++P++KA + VD Q AE +A+++G R
Sbjct 121 SRAPYVMGKSEGAFGRTQKIEDTTMGWRFINPKLKAMYGVDTMPQ--TAENVAEQFGIQR 178
Query 172 EQLDQYALLSHQRAIQATETGNFENEIVVLDV---DGEAHRI--DEGIRFDANLESVSGL 226
E DQ+A S QR A G F EIV + + GE I DE R LE ++ L
Sbjct 179 EDQDQFAYTSQQRTAAAQAKGYFAKEIVPVTIPQRKGEPVVIATDEHPRASTTLEGLAKL 238
Query 227 KPLVE-NGVVTAANASQICDGASAVLIVSERALKAYDLTPKARLIHMSVSAGDPVMMLEE 285
K +V+ G VTA NAS I DGA+AVLI S+ A+ Y L +A++I + +P +M
Sbjct 239 KGVVKPEGSVTAGNASGINDGAAAVLIASDEAVAQYQLKARAKIIASTTVGIEPRIMGFA 298
Query 286 PIFATQKALKKAGLKITDIDLYEVNEAFAPVPLAWLQALD-ANPEA-LNIHGGAIALGHP 343
P A +K LK+A L + +D+ E+NEAFA LA + L A+ +A +N +GGAIALGHP
Sbjct 299 PAPAIKKLLKQANLTLDQMDVIELNEAFAAQALACTRDLGLADDDARVNPNGGAIALGHP 358
Query 344 LGASGTKLMTTLIHALHTQGKRYGLQTMCEGGGMANVTILE 384
LGASG +L+TT ++ L G +Y L +MC G G I+E
Sbjct 359 LGASGARLVTTALNQLEQSGGKYALCSMCIGVGQGIALIIE 399
>P0C7L3 Beta-ketoadipyl-CoA thiolase [Escherichia coli]
Length=401
Score = 244 bits (624), Expect = 9e-81
Identities = 164/400 (41%), Positives = 221/400 (55%), Gaps = 17/400 (4%)
Query 1 MNVAYIVDAVRTAGGRRNGKLASWHPVDLGAEVINALLDRTG-IDPNVIDDAVFGCVTQA 59
M A+I D +RT GR G L+ DL A + LL R +D IDD + GC QA
Sbjct 1 MREAFICDGIRTPIGRYGGALSGVRADDLAAIPLRELLVRNPRLDAECIDDVILGCANQA 60
Query 60 GEQTFAFARNIVLASKLPIHVPGVTIDRQCGSSQQAVQFAAQAILSGMQDVVIAGGVESM 119
GE AR L + LP V G TI+R CGS A+ FAA+AI +G D++IAGGVESM
Sbjct 61 GEDNRNVARMATLLAGLPQSVSGTTINRLCGSGLDALGFAARAIKAGDGDLLIAGGVESM 120
Query 120 SRAPMLSNASLHAKAGLPADPLSPRIKARFDVDQFSQFTG-------AEMMAKKYGFDRE 172
SRAP + + A + A+ I RF +Q G AE +A+ RE
Sbjct 121 SRAPFVMGKATSAFSR-QAEMFDTTIGWRFVNPLMAQQFGTDSMPETAENVAELLKISRE 179
Query 173 QLDQYALLSHQRAIQATETGNFENEIVVLDVDGEAHRI-----DEGIRFDANLESVSGLK 227
D +AL S QR +A +G EIV + + + + DE +R + LE + GLK
Sbjct 180 DQDSFALRSQQRTAKAQSSGILAEEIVPVVLKNKKGVVTEIQHDEHLRPETTLEQLRGLK 239
Query 228 -PLVENGVVTAANASQICDGASAVLIVSERALKAYDLTPKARLIHMSVSAGDPVMMLEEP 286
P NGV+TA NAS + DGA+A++I SE+ A LTP+AR++ M+ + +P +M P
Sbjct 240 APFRANGVITAGNASGVNDGAAALIIASEQMAAAQGLTPRARIVAMATAGVEPRLMGLGP 299
Query 287 IFATQKALKKAGLKITDIDLYEVNEAFAPVPLAWLQALDANPEA--LNIHGGAIALGHPL 344
+ AT++ L++AGL I D+D+ E+NEAFA L L+ L +A +N +GGAIALGHPL
Sbjct 300 VPATRRVLERAGLSIHDMDVIELNEAFAAQALGVLRELGLPDDAPHVNPNGGAIALGHPL 359
Query 345 GASGTKLMTTLIHALHTQGKRYGLQTMCEGGGMANVTILE 384
G SG +L H LH + RY L TMC G G ILE
Sbjct 360 GMSGARLALAASHELHRRNGRYALCTMCIGVGQGIAMILE 399
>P28790 3-ketoacyl-CoA thiolase [Pseudomonas fragi]
Length=391
Score = 243 bits (621), Expect = 2e-80
Identities = 157/392 (40%), Positives = 219/392 (56%), Gaps = 25/392 (6%)
Query 6 IVDAVRTAGGRRNGKL-ASWHPVDLGAEVINALLDRTG-IDPNVIDDAVFGCVTQAGEQT 63
IVD RT GR G + + D+ A +I+ +L+R +DP ++D ++GCV Q EQ
Sbjct 10 IVDFGRTPMGRSKGGMHRNTRAEDMSAHLISKVLERNSKVDPGEVEDVIWGCVNQTLEQG 69
Query 64 FAFARNIVLASKLPIHVPGVTIDRQCGSSQQAVQFAAQAILSGMQDVVIAGGVESMSRAP 123
+ AR L +++P T+ R CGSS A+ AAQAI++G DV + GGVE M
Sbjct 70 WNIARMASLMTQIPHTSAAQTVSRLCGSSMSALHTAAQAIMTGNGDVFVVGGVEHMGHVS 129
Query 124 MLSNASLHAKAGLPADPLSPRIKARFDVDQFSQFTGAEMMAKKYGFDREQLDQYALLSHQ 183
M+ + L A S + AEM+ K +G REQ D +A+ SHQ
Sbjct 130 MMHGVDPNPHMSLYAAKASGMMGLT-----------AEMLGKMHGISREQQDAFAVRSHQ 178
Query 184 RAIQATETGNFENEIVVL---DVDG--EAHRIDEGIRFDANLESVSGLKPLV--ENGVVT 236
A +AT G F++EI+ + D +G + DE IR D LES++ LKP + G VT
Sbjct 179 LAHKATVEGKFKDEIIPMQGYDENGFLKIFDYDETIRPDTTLESLAALKPAFNPKGGTVT 238
Query 237 AANASQICDGASAVLIVSERALKAYDLTPKARLIHMSVSAGDPVMMLEEPIFATQKALKK 296
A +SQI DGAS ++++S + K L P A + M+V+ DP +M P+ ATQKALK+
Sbjct 239 AGTSSQITDGASCMIVMSAQRAKDLGLEPLAVIRSMAVAGVDPAIMGYGPVPATQKALKR 298
Query 297 AGLKITDIDLYEVNEAFA----PVPLAWLQALDANPEALNIHGGAIALGHPLGASGTKLM 352
AGL + DID E+NEAFA PV L L+ LD E +N+HGGAIALGHP G SG ++
Sbjct 299 AGLNMADIDFIELNEAFAAQALPV-LKDLKVLDKMNEKVNLHGGAIALGHPFGCSGARIS 357
Query 353 TTLIHALHTQGKRYGLQTMCEGGGMANVTILE 384
TL++ + G +GL TMC G G T+ E
Sbjct 358 GTLLNVMKQNGGTFGLSTMCIGLGQGIATVFE 389
>P21151 3-ketoacyl-CoA thiolase FadA [Escherichia coli (strain
K12)]
Length=387
Score = 241 bits (614), Expect = 2e-79
Identities = 151/396 (38%), Positives = 221/396 (56%), Gaps = 23/396 (6%)
Query 1 MNVAYIVDAVRTAGGR-RNGKLASWHPVDLGAEVINALLDRT-GIDPNVIDDAVFGCVTQ 58
M IVDA+RT GR + G + DL A ++ +LL R ++ +DD +GCV Q
Sbjct 1 MEQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPALEAAALDDIYWGCVQQ 60
Query 59 AGEQTFAFARNIVLASKLPIHVPGVTIDRQCGSSQQAVQFAAQAILSGMQDVVIAGGVES 118
EQ F ARN L +++P VP VT++R CGSS QA+ AA+ I++G + GGVE
Sbjct 61 TLEQGFNIARNAALLAEVPHSVPAVTVNRLCGSSMQALHDAARMIMTGDAQACLVGGVEH 120
Query 119 MSRAPMLSNASLHAKAGLPADPLSPRIKARFDVDQFSQFTGAEMMAKKYGFDREQLDQYA 178
M PM H P + AEM+A+ +G RE D +A
Sbjct 121 MGHVPMSHGVDFH-----------PGLSRNVAKAAGMMGLTAEMLARMHGISREMQDAFA 169
Query 179 LLSHQRAIQATETGNFENEIVVL---DVDG--EAHRIDEGIRFDANLESVSGLKPLVE-- 231
SH RA AT++ F+NEI+ D DG + DE IR + +E+++ L+P +
Sbjct 170 ARSHARAWAATQSAAFKNEIIPTGGHDADGVLKQFNYDEVIRPETTVEALATLRPAFDPV 229
Query 232 NGVVTAANASQICDGASAVLIVSERALKAYDLTPKARLIHMSVSAGDPVMMLEEPIFATQ 291
NG+VTA +S + DGA+A+L++SE L P+AR+ M+V DP +M P+ A++
Sbjct 230 NGMVTAGTSSALSDGAAAMLVMSESRAHELGLKPRARVRSMAVVGCDPSIMGYGPVPASK 289
Query 292 KALKKAGLKITDIDLYEVNEAFAPVPLAWLQAL---DANPEALNIHGGAIALGHPLGASG 348
ALKKAGL +DI ++E+NEAFA L ++ L + E +N++GGAIALGHPLG SG
Sbjct 290 LALKKAGLSASDIGVFEMNEAFAAQILPCIKDLGLIEQIDEKINLNGGAIALGHPLGCSG 349
Query 349 TKLMTTLIHALHTQGKRYGLQTMCEGGGMANVTILE 384
++ TTL++ + + ++GL TMC G G T+ E
Sbjct 350 ARISTTLLNLMERKDVQFGLATMCIGLGQGIATVFE 385
>Q9ZHI1 Acetyl-CoA acetyltransferase [Chromobacterium violaceum
(strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB
9131 / NCTC 9757)]
Length=392
Score = 239 bits (611), Expect = 6e-79
Identities = 157/393 (40%), Positives = 224/393 (57%), Gaps = 12/393 (3%)
Query 1 MNVAYIVDAVRTAGGRRNGKLASWHPVDLGAEVINALLDRTGIDPNVIDDAVFGCVTQAG 60
M VA IV A RTA G G LA +LGA VI ALL++TG+ P + + + G V AG
Sbjct 1 MEVA-IVAAQRTAIGSFGGGLAKIPAPELGATVIKALLEKTGVKPEDVSEVILGQVLTAG 59
Query 61 EQTFAFARNIVLASKLPIHVPGVTIDRQCGSSQQAVQFAAQAILSGMQDVVIAGGVESMS 120
AR ++ + LP+ P T++ CGS +AV AAQAIL+G D+VIAGG ESMS
Sbjct 60 SGQNP-ARQALIKAGLPVTTPATTLNVVCGSGLRAVHLAAQAILAGDADIVIAGGQESMS 118
Query 121 RAPMLSNASLHAKAGLPADPLSPRIKARFDVDQFSQF---TGAEMMAKKYGFDREQLDQY 177
+P + S A + + D ++ + AE +A KYG RE+ D +
Sbjct 119 LSPHILPGSRDGFRMGNAQLVDTMVNDGL-TDAYNAYHMGITAENVAAKYGIGREEQDAF 177
Query 178 ALLSHQRAIQATETGNFENEIVVLDV-----DGEAHRIDEGIRFDANLESVSGLKPLVE- 231
+L S QRA A + G F +EIV + V D A DE I+ DA+ + ++ L+P +
Sbjct 178 SLQSQQRAAAAQKAGKFRDEIVPVLVPQRKGDPLAFDADEFIKHDASADGLAKLRPAFKK 237
Query 232 NGVVTAANASQICDGASAVLIVSERALKAYDLTPKARLIHMSVSAGDPVMMLEEPIFATQ 291
+G VTA NAS I DGA+AVL++S + L P A + +++ +P +M P+ AT+
Sbjct 238 DGTVTAGNASGINDGAAAVLLMSTQKADQLGLKPLAIIKGYALTGCEPEIMGIGPVSATR 297
Query 292 KALKKAGLKITDIDLYEVNEAFAPVPLAWLQALDANPEALNIHGGAIALGHPLGASGTKL 351
KAL KAG + D+DL E NEAFA L + L + +N++GGAIALGHP+GASG ++
Sbjct 298 KALSKAGWTVEDLDLVEANEAFAAQALGVAKELGWGSDKVNVNGGAIALGHPIGASGCRV 357
Query 352 MTTLIHALHTQGKRYGLQTMCEGGGMANVTILE 384
+ TL+H + +G + GL T+C GGGM +E
Sbjct 358 LVTLLHEMQRRGAKKGLATLCIGGGMGVALAVE 390
Lambda K H a alpha
0.320 0.134 0.387 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 2504544
Database: e7a9f15578ab809b1411e8ac6bee00bb.SwissProt.fasta
Posted date: May 9, 2024 3:12 PM
Number of letters in database: 8,598
Number of sequences in database: 22
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
