BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 4c842222e76cd8bb60edfad3f5f9291c.SwissProt.fasta
10 sequences; 3,684 total letters
Query= ACIAD1578
Length=372
Score E
Sequences producing significant alignments: (Bits) Value
P39849 Aryl-alcohol dehydrogenase [Pseudomonas putida] 342 5e-120
H1ZV38 Geraniol dehydrogenase [Castellaniella defragrans (strain ... 313 1e-108
P33010 Probable alcohol dehydrogenase [Pseudomonas sp] 275 2e-94
P41680 Alcohol dehydrogenase 1 [Peromyscus maniculatus] 197 3e-63
P06757 Alcohol dehydrogenase 1 [Rattus norvegicus] 194 5e-62
O97959 Alcohol dehydrogenase 1C [Papio hamadryas] 192 1e-61
Q03505 Alcohol dehydrogenase 1 [Oryctolagus cuniculus] 191 5e-61
P00329 Alcohol dehydrogenase 1 [Mus musculus] 190 1e-60
P00325 All-trans-retinol dehydrogenase [NAD(+)] ADH1B [Homo sapiens] 190 1e-60
P07327 Alcohol dehydrogenase 1A [Homo sapiens] 189 3e-60
>P39849 Aryl-alcohol dehydrogenase [Pseudomonas putida]
Length=366
Score = 342 bits (878), Expect = 5e-120
Identities = 179/365 (49%), Positives = 240/365 (66%), Gaps = 3/365 (1%)
Query 1 MKITAAVARQAHQDFSIEQVELDEPKDHEVLVRIEGVGLCHTDLVARDRLIPIPLPAVLG 60
M+I AA+ RQ + F +E V L+EP + +VLVR+ GLCHTDLV RD+ P+PLP V G
Sbjct 1 MEIKAAIVRQKNGPFLLEHVALNEPAEDQVLVRLVATGLCHTDLVCRDQHYPVPLPMVFG 60
Query 61 HEGAGVVEKIGKAVTKVAVGDHVLMSFNSCGECPRCKEHLPPYCTQFPQLNYVGARPDGS 120
HEGAGVVE++G AV KV GDHV+++F +CG C C P C N++G G
Sbjct 61 HEGAGVVERVGSAVKKVQPGDHVVLTFYTCGSCDACLSGDPTSCANSFGPNFMGRSVTGE 120
Query 121 STLKQNDQA-VSGYFFGQSSFASHALANERNIVKVAQDLPIEILGPLGCGLQTGAGGVMR 179
T+ + A V FFGQSSFA++AL+ ERN VKV +D+P+E+LGPLGCG+QTGAG V+
Sbjct 121 CTIHDHQGAEVGASFFGQSSFATYALSYERNTVKVTKDVPLELLGPLGCGIQTGAGSVLN 180
Query 180 SLACPQGSTIAIFGGGPVGLAAVMGAVIQQCATIILVEPMASRRELALELGAHHVIDPAQ 239
+L P GS IAIFG G VGL+AVM AV+ C TII V+ +R ELA ELGA H+I+PA
Sbjct 181 ALNPPAGSAIAIFGAGAVGLSAVMAAVVAGCTTIIAVDVKENRLELASELGATHIINPAA 240
Query 240 GNITEHIRNILPQGVDFAFESSGRGEVVEAALASLGSHGLLGLVGVPPSVETTLNVNLVS 299
+ E I+ I GV + E+SG V+ A+ S G +G+VG PP + T+ V+ ++
Sbjct 241 NDPIEAIKEIFADGVPYVLETSGLPAVLTQAILSSAIGGEIGIVGAPP-MGATVPVD-IN 298
Query 300 LITFGHRIHGIIEGDSDLDTFLPELIQHYQAGKFPFDKLIKKYALSEINQAIQDQAQGRC 359
+ F ++ GI+EG S D F+P L++ Y+ GKFPFDKLIK Y EIN+A +D +G
Sbjct 299 FLLFNRKLRGIVEGQSISDIFIPRLVELYRQGKFPFDKLIKFYPFDEINRAAEDSEKGVT 358
Query 360 IKAVL 364
+K VL
Sbjct 359 LKPVL 363
>H1ZV38 Geraniol dehydrogenase [Castellaniella defragrans (strain
DSM 12143 / CCUG 39792 / 65Phen)]
Length=373
Score = 313 bits (803), Expect = 1e-108
Identities = 164/363 (45%), Positives = 229/363 (63%), Gaps = 4/363 (1%)
Query 5 AAVARQAHQDFSIEQVELDEPKDHEVLVRIEGVGLCHTDLVARDRLIPIPLPAVLGHEGA 64
AAV RQ ++E V + PK EVL+RI GVG+CHTDLV RD P+PLP VLGHEG+
Sbjct 12 AAVLRQVGGPLAVEPVRISMPKGDEVLIRIAGVGVCHTDLVCRDGF-PVPLPIVLGHEGS 70
Query 65 GVVEKIGKAVTKVAVGDHVLMSFNSCGECPRCKEHLPPYCTQFPQLNYVGA-RPDGSSTL 123
G VE +G+ V + GD V++SFNSCG C C + P C Q LN+ GA R DG L
Sbjct 71 GTVEAVGEQVRTLKPGDRVVLSFNSCGHCGNCHDGHPSNCLQMLPLNFGGAQRVDGGQVL 130
Query 124 KQNDQAVSGYFFGQSSFASHALANERNIVKVAQDLPIEILGPLGCGLQTGAGGVMRSLAC 183
V FFGQSSF +HA+A E N VKV DLP+E+LGPLGCG+QTGAG + SL
Sbjct 131 DGAGHPVQSMFFGQSSFGTHAVAREINAVKVGDDLPLELLGPLGCGIQTGAGAAINSLGI 190
Query 184 PQGSTIAIFGGGPVGLAAVMGAVIQQCATIILVEPMASRRELALELGAHHVIDP-AQGNI 242
G ++AIFGGG VGL+A++GA ++++EP A+RR LALELGA H +DP A+G++
Sbjct 191 GPGQSLAIFGGGGVGLSALLGARAVGADRVVVIEPNAARRALALELGASHALDPHAEGDL 250
Query 243 TEHIRNILPQGVDFAFESSGRGEVVEAALASLGSHGLLGLVGVPPSVETTLNVNLVSLIT 302
I+ G + +++G V+ +A+A G +G+VG+ P+ + + L+ L++
Sbjct 251 VAAIKAATGGGATHSLDTTGLPPVIGSAIACTLPGGTVGMVGL-PAPDAPVPATLLDLLS 309
Query 303 FGHRIHGIIEGDSDLDTFLPELIQHYQAGKFPFDKLIKKYALSEINQAIQDQAQGRCIKA 362
+ I EGD+D F+P ++ ++AGKFPFD+LI +Y +IN+A+ +G IK
Sbjct 310 KSVTLRPITEGDADPQRFIPRMLDFHRAGKFPFDRLITRYRFDQINEALHATEKGEAIKP 369
Query 363 VLI 365
VL+
Sbjct 370 VLV 372
>P33010 Probable alcohol dehydrogenase [Pseudomonas sp]
Length=319
Score = 275 bits (704), Expect = 2e-94
Identities = 139/281 (49%), Positives = 185/281 (66%), Gaps = 4/281 (1%)
Query 39 LCHTDLVARDRLIPIPLPAVLGHEGAGVVEKIGKAVTKVAVGDHVLMSFNSCGECPRCKE 98
+CHTDL +D ++P PLPAVLGHEG+G+VE +G V + GD V+M+F SCG C C+
Sbjct 17 VCHTDLAIKDGVLPFPLPAVLGHEGSGIVEAVGPGVKHLKPGDAVVMTFASCGHCASCEH 76
Query 99 HLPPYCTQFPQLNYVGARPDGSSTLKQNDQAVSGYFFGQSSFASHALANERNIVKV---A 155
P YC F NY R DG L Q D+ +SG+FFGQSSF+S A+A E N+VK+
Sbjct 77 ERPSYCLDFGAQNYSAQRADGPVLLSQGDEVISGFFFGQSSFSSMAMAREHNLVKIDALV 136
Query 156 QDLPIEILGPLGCGLQTGAGGVMRSLACPQGSTIAIFGGGPVGLAAVMGAVIQQCATIIL 215
D PIE+LGPLGCG+QTGAG VM SL G + + GGG VGL+AVM A ++ C+ II+
Sbjct 137 DDAPIELLGPLGCGVQTGAGAVMISLDVRAGRSFLVLGGGAVGLSAVMAAKLRGCSRIIV 196
Query 216 VEPMASRRELALELGAHHVIDPAQGNITEHIRNILP-QGVDFAFESSGRGEVVEAALASL 274
EP A++RE AL LGA VIDP N+ E ++ I QG D+A E +G V+E A+ S+
Sbjct 197 SEPSAAKREQALALGATEVIDPLNENLVERVQQITEGQGCDYALECTGLVSVMEQAIDSM 256
Query 275 GSHGLLGLVGVPPSVETTLNVNLVSLITFGHRIHGIIEGDS 315
G L +VGVPP ++ T V+ ++LI G ++ G+IEGDS
Sbjct 257 AMRGQLAVVGVPPKLDATAAVSPLALIQKGLKLMGVIEGDS 297
>P41680 Alcohol dehydrogenase 1 [Peromyscus maniculatus]
Length=375
Score = 197 bits (500), Expect = 3e-63
Identities = 130/369 (35%), Positives = 196/369 (53%), Gaps = 8/369 (2%)
Query 1 MKITAAVARQAHQDFSIEQVELDEPKDHEVLVRIEGVGLCHTDLVARDRLIPIPLPAVLG 60
+K AAV + H+ FSIE +E+ PK HEV +++ G+C +D R + PLPAVLG
Sbjct 8 IKCKAAVLWEPHKPFSIEDIEVAPPKAHEVRIKMVATGVCRSDDHVVSRSLASPLPAVLG 67
Query 61 HEGAGVVEKIGKAVTKVAVGDHVLMSFN-SCGECPRCKEHLPPYCTQFPQLNYVGARPDG 119
HEGAG+VE +G+ VT V GD V+ F CG+C CK C + + G DG
Sbjct 68 HEGAGIVESVGEGVTSVKPGDKVIPLFTPQCGKCRICKHPEYNLCMKNDLMQPRGTLLDG 127
Query 120 SSTLKQNDQAVSGYFFGQSSFASHALANERNIVKVAQDLPIEILGPLGCGLQTGAGGVMR 179
+S +A+ F S+F+ + + +E + K+ P+E + +GCG TG G ++
Sbjct 128 TSRFTCRGKAIHN-FISTSTFSQYTVVDEMAVAKIDGASPLEKVCLIGCGFSTGYGSAVK 186
Query 180 SLACPQGSTIAIFGGGPVGLAAVMGAVIQQCATIILVEPMASRRELALELGAHHVIDPAQ 239
GST A+FG G VGL+ ++G A II V+ + A ELGA I+P
Sbjct 187 VAKVTPGSTCAVFGLGGVGLSVIIGCKAAGAARIIAVDINKDKFAKAKELGATECINPLD 246
Query 240 GN--ITEHIRNILPQGVDFAFESSGRGEVVEAALASL-GSHGLLGLVGVPPSVETTLNVN 296
+ I E ++ + GVDF+FE GR + + ++L S S G+ +VGVPP+ + +L+VN
Sbjct 247 YSKPIQEVLQEMTDGGVDFSFEVIGRLDTMTSSLLSCHASCGVSVIVGVPPNAQ-SLSVN 305
Query 297 LVSLITFGHRIHGIIEGDSDLDTFLPELIQHYQAGKFPFDKLIKK-YALSEINQAIQDQA 355
+SL+ G G I G +P+L+ + A KFP + LI +IN+A
Sbjct 306 PMSLL-MGRSWKGAIFGGFKSKDSVPKLVTDFMAKKFPLEPLITHVLPFEKINEAFDLLR 364
Query 356 QGRCIKAVL 364
G+ I+ VL
Sbjct 365 AGKSIRTVL 373
>P06757 Alcohol dehydrogenase 1 [Rattus norvegicus]
Length=376
Score = 194 bits (492), Expect = 5e-62
Identities = 133/370 (36%), Positives = 197/370 (53%), Gaps = 9/370 (2%)
Query 1 MKITAAVARQAHQDFSIEQVELDEPKDHEVLVRIEGVGLCHTDLVARDRLIPIPLPAVLG 60
+K AAV + H+ F+IE +E+ PK HEV +++ G+C +D A + PLPAVLG
Sbjct 8 IKCKAAVLWEPHKPFTIEDIEVAPPKAHEVRIKMVATGVCRSDDHAVSGSLFTPLPAVLG 67
Query 61 HEGAGVVEKIGKAVTKVAVGDHVLMSFN-SCGECPRCKEHLPPYCTQFPQLNY-VGARPD 118
HEGAG+VE IG+ VT V GD V+ F+ CG+C CK C Q L GA D
Sbjct 68 HEGAGIVESIGEGVTCVKPGDKVIPLFSPQCGKCRICKHPESNLCCQTKNLTQPKGALLD 127
Query 119 GSSTLKQNDQAVSGYFFGQSSFASHALANERNIVKVAQDLPIEILGPLGCGLQTGAGGVM 178
G+S + + +F S+F+ + + ++ + K+ P++ + +GCG TG G +
Sbjct 128 GTSRFSCRGKPIH-HFISTSTFSQYTVVDDIAVAKIDAAAPLDKVCLIGCGFSTGYGSAV 186
Query 179 RSLACPQGSTIAIFGGGPVGLAAVMGAVIQQCATIILVEPMASRRELALELGAHHVIDPA 238
+ GST A+FG G VGL+ V+G A II V+ + A ELGA I+P
Sbjct 187 QVAKVTPGSTCAVFGLGGVGLSVVIGCKTAGAAKIIAVDINKDKFAKAKELGATDCINPQ 246
Query 239 QGN--ITEHIRNILPQGVDFAFESSGRGEVVEAALASLGSH-GLLGLVGVPPSVETTLNV 295
I E ++ + GVDF+FE GR + + +AL S S G+ +VGVPPS + +L+V
Sbjct 247 DYTKPIQEVLQEMTDGGVDFSFEVIGRLDTMTSALLSCHSACGVSVIVGVPPSAQ-SLSV 305
Query 296 NLVSLITFGHRIHGIIEGDSDLDTFLPELIQHYQAGKFPFDKLIKK-YALSEINQAIQDQ 354
N +SL+ G G I G +P+L+ + A KFP + LI +IN+A
Sbjct 306 NPMSLL-LGRTWKGAIFGGFKSKDAVPKLVADFMAKKFPLEPLITHVLPFEKINEAFDLL 364
Query 355 AQGRCIKAVL 364
G+ I+ VL
Sbjct 365 RAGKSIRTVL 374
>O97959 Alcohol dehydrogenase 1C [Papio hamadryas]
Length=375
Score = 192 bits (489), Expect = 1e-61
Identities = 131/372 (35%), Positives = 193/372 (52%), Gaps = 12/372 (3%)
Query 1 MKITAAVARQAHQDFSIEQVELDEPKDHEVLVRIEGVGLCHTDLVARDRLIPIPLPAVLG 60
+K AAV + + FSIE+VE+ PK HEV +++ VG+C +D + PLPA+LG
Sbjct 8 IKCKAAVLWEVKKPFSIEEVEVAPPKAHEVRIKMVAVGICRSDDHVVSGTLVTPLPAILG 67
Query 61 HEGAGVVEKIGKAVTKVAVGDHVLMSFN-SCGECPRCKEHLPPYCTQFPQLNYVGARPDG 119
HE AG+VE +G+ VT V GD V+ F CG+C CK YC + N G DG
Sbjct 68 HEAAGIVEGVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCFKNDLSNPRGTMQDG 127
Query 120 SSTLKQNDQAVSGYFFGQSSFASHALANERNIVKVAQDLPIEILGPLGCGLQTGAGGVMR 179
+ + + +F G S+F+ + + +E + K+ P+E + +GCG TG G ++
Sbjct 128 TRRFTCGGKPIH-HFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGPAVK 186
Query 180 SLACPQGSTIAIFGGGPVGLAAVMGAVIQQCATIILVEPMASRRELALELGAHHVIDPA- 238
GST A+FG G VGL+AVMG A II V+ + A ELGA I+P
Sbjct 187 VAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246
Query 239 -QGNITEHIRNILPQGVDFAFESSGRGEVVEAALASLGSHGLLG---LVGVPPSVETTLN 294
+ I E ++ + GVDF+FE GR + + A+L L H G +VGVPP + L+
Sbjct 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTIMASL--LCCHEACGTSVIVGVPPDSQ-NLS 303
Query 295 VNLVSLITFGHRIHGIIEGDSDLDTFLPELIQHYQAGKFPFDKLIKK-YALSEINQAIQD 353
+N V L+T G G I G +P+L+ + A KF D LI +IN+
Sbjct 304 INPVLLLT-GRTWKGAIFGGFKSKESVPKLVSDFMAKKFSLDALITNVLPFEKINEGFDL 362
Query 354 QAQGRCIKAVLI 365
G+ I+ +L+
Sbjct 363 LRSGKSIRTILM 374
>Q03505 Alcohol dehydrogenase 1 [Oryctolagus cuniculus]
Length=375
Score = 191 bits (485), Expect = 5e-61
Identities = 131/369 (36%), Positives = 192/369 (52%), Gaps = 8/369 (2%)
Query 1 MKITAAVARQAHQDFSIEQVELDEPKDHEVLVRIEGVGLCHTDLVARDRLIPIPLPAVLG 60
+K AAV Q ++ FSIE+VE+ PK HEV +++ G+C +D A I +PLP +LG
Sbjct 8 IKCKAAVLWQLNKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHAVTGSIAVPLPVILG 67
Query 61 HEGAGVVEKIGKAVTKVAVGDHVLMSFN-SCGECPRCKEHLPPYCTQFPQLNYVGARPDG 119
HE AG+VE IG+ VT V GD V+ F CG+C CK +C G DG
Sbjct 68 HEAAGIVESIGEGVTTVKPGDKVIPLFTPQCGKCRICKHPESNFCLINDLGKPKGMLLDG 127
Query 120 SSTLKQNDQAVSGYFFGQSSFASHALANERNIVKVAQDLPIEILGPLGCGLQTGAGGVMR 179
+S + + +F G S+F+ + + +E + K+ P+E + +GCG TG G ++
Sbjct 128 TSRFTCKGKPIH-HFIGTSTFSQYTVVDEIAVAKIDAAAPLEKVCLIGCGFSTGYGSAVK 186
Query 180 SLACPQGSTIAIFGGGPVGLAAVMGAVIQQCATIILVEPMASRRELALELGAHHVIDPA- 238
GST A+FG G VGL+ +MG + II V+ + A E+GA I+P
Sbjct 187 VAKVTPGSTCAVFGLGGVGLSVIMGCKAAGASRIIAVDINKDKFPKAKEVGATECINPQD 246
Query 239 -QGNITEHIRNILPQGVDFAFESSGRGEVVEAALASL-GSHGLLGLVGVPPSVETTLNVN 296
+ I E I+ I GVDF+FE GR + V AAL S G+ G +VGVPP + +L VN
Sbjct 247 YKKPIQEVIQEISDGGVDFSFEVIGRLDTVVAALLSCHGACGTSVIVGVPPDSQ-SLTVN 305
Query 297 LVSLITFGHRIHGIIEGDSDLDTFLPELIQHYQAGKFPFDKLIKK-YALSEINQAIQDQA 355
+ L++ G G I G +P+L+ + A KF D LI +IN+
Sbjct 306 PMLLLS-GRTWKGAIFGGFKSKDSVPKLVADFMAKKFSLDPLITNVLPFEKINEGFDLLR 364
Query 356 QGRCIKAVL 364
G+ I+ +L
Sbjct 365 SGKSIRTIL 373
>P00329 Alcohol dehydrogenase 1 [Mus musculus]
Length=375
Score = 190 bits (482), Expect = 1e-60
Identities = 125/369 (34%), Positives = 195/369 (53%), Gaps = 8/369 (2%)
Query 1 MKITAAVARQAHQDFSIEQVELDEPKDHEVLVRIEGVGLCHTDLVARDRLIPIPLPAVLG 60
+K AAV + H+ F+IE +E+ PK HEV +++ G+C +D + PLPAVLG
Sbjct 8 IKCKAAVLWELHKPFTIEDIEVAPPKAHEVRIKMVATGVCRSDDHVVSGTLVTPLPAVLG 67
Query 61 HEGAGVVEKIGKAVTKVAVGDHVLMSFN-SCGECPRCKEHLPPYCTQFPQLNYVGARPDG 119
HEGAG+VE +G+ VT V GD V+ F+ CGEC CK +C++ L G +G
Sbjct 68 HEGAGIVESVGEGVTCVKPGDKVIPLFSPQCGECRICKHPESNFCSRSDLLMPRGTLREG 127
Query 120 SSTLKQNDQAVSGYFFGQSSFASHALANERNIVKVAQDLPIEILGPLGCGLQTGAGGVMR 179
+S + + F S+F+ + + ++ + K+ P++ + +GCG TG G ++
Sbjct 128 TSRFSCKGKQIHN-FISTSTFSQYTVVDDIAVAKIDGASPLDKVCLIGCGFSTGYGSAVK 186
Query 180 SLACPQGSTIAIFGGGPVGLAAVMGAVIQQCATIILVEPMASRRELALELGAHHVIDPAQ 239
GST A+FG G VGL+ ++G A II V+ + A ELGA I+P
Sbjct 187 VAKVTPGSTCAVFGLGGVGLSVIIGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246
Query 240 GN--ITEHIRNILPQGVDFAFESSGRGEVVEAALASL-GSHGLLGLVGVPPSVETTLNVN 296
+ I E ++ + GVDF+FE GR + + +AL S + G+ +VGVPP+ + L++N
Sbjct 247 YSKPIQEVLQEMTDGGVDFSFEVIGRLDTMTSALLSCHAACGVSVVVGVPPNAQ-NLSMN 305
Query 297 LVSLITFGHRIHGIIEGDSDLDTFLPELIQHYQAGKFPFDKLIKK-YALSEINQAIQDQA 355
+ L+ G G I G +P+L+ + A KFP D LI +IN+A
Sbjct 306 PM-LLLLGRTWKGAIFGGFKSKDSVPKLVADFMAKKFPLDPLITHVLPFEKINEAFDLLR 364
Query 356 QGRCIKAVL 364
G+ I+ VL
Sbjct 365 SGKSIRTVL 373
>P00325 All-trans-retinol dehydrogenase [NAD(+)] ADH1B [Homo sapiens]
Length=375
Score = 190 bits (482), Expect = 1e-60
Identities = 130/371 (35%), Positives = 191/371 (51%), Gaps = 12/371 (3%)
Query 1 MKITAAVARQAHQDFSIEQVELDEPKDHEVLVRIEGVGLCHTDLVARDRLIPIPLPAVLG 60
+K AAV + + FSIE VE+ PK +EV +++ VG+CHTD + PLP +LG
Sbjct 8 IKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICHTDDHVVSGNLVTPLPVILG 67
Query 61 HEGAGVVEKIGKAVTKVAVGDHVLMSFN-SCGECPRCKEHLPPYCTQFPQLNYVGARPDG 119
HE AG+VE +G+ VT V GD V+ F CG+C CK YC + N G DG
Sbjct 68 HEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDG 127
Query 120 SSTLKQNDQAVSGYFFGQSSFASHALANERNIVKVAQDLPIEILGPLGCGLQTGAGGVMR 179
+ + + +F G S+F+ + + +E + K+ P+E + +GCG TG G +
Sbjct 128 TRRFTCRGKPIH-HFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVN 186
Query 180 SLACPQGSTIAIFGGGPVGLAAVMGAVIQQCATIILVEPMASRRELALELGAHHVIDPA- 238
GST A+FG G VGL+AVMG A II V+ + A ELGA I+P
Sbjct 187 VAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246
Query 239 -QGNITEHIRNILPQGVDFAFESSGRGEVVEAALASLGSHGLLG---LVGVPPSVETTLN 294
+ I E ++ + GVDF+FE GR + + A+L L H G +VGVPP+ + L+
Sbjct 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASL--LCCHEACGTSVIVGVPPASQ-NLS 303
Query 295 VNLVSLITFGHRIHGIIEGDSDLDTFLPELIQHYQAGKFPFDKLIKK-YALSEINQAIQD 353
+N + L+T G G + G +P+L+ + A KF D LI +IN+
Sbjct 304 INPMLLLT-GRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDL 362
Query 354 QAQGRCIKAVL 364
G+ I+ VL
Sbjct 363 LHSGKSIRTVL 373
>P07327 Alcohol dehydrogenase 1A [Homo sapiens]
Length=375
Score = 189 bits (480), Expect = 3e-60
Identities = 129/372 (35%), Positives = 193/372 (52%), Gaps = 12/372 (3%)
Query 1 MKITAAVARQAHQDFSIEQVELDEPKDHEVLVRIEGVGLCHTDLVARDRLIPIPLPAVLG 60
+K AAV + + FSIE+VE+ PK HEV +++ VG+C TD + PLP +LG
Sbjct 8 IKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILG 67
Query 61 HEGAGVVEKIGKAVTKVAVGDHVL-MSFNSCGECPRCKEHLPPYCTQFPQLNYVGARPDG 119
HE AG+VE +G+ VT V GD V+ ++ CG+C CK YC + N G DG
Sbjct 68 HEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDG 127
Query 120 SSTLKQNDQAVSGYFFGQSSFASHALANERNIVKVAQDLPIEILGPLGCGLQTGAGGVMR 179
+S + + +F G S+F+ + + +E + K+ P+E + +GCG TG G +
Sbjct 128 TSRFTCRRKPIH-HFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVN 186
Query 180 SLACPQGSTIAIFGGGPVGLAAVMGAVIQQCATIILVEPMASRRELALELGAHHVIDPA- 238
GST A+FG G VGL+A+MG A II V+ + A ELGA I+P
Sbjct 187 VAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQD 246
Query 239 -QGNITEHIRNILPQGVDFAFESSGRGEVVEAALASLGSHGLLG---LVGVPPSVETTLN 294
+ I E ++ + GVDF+FE GR + + A+L L H G +VGVPP + L+
Sbjct 247 YKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASL--LCCHEACGTSVIVGVPPDSQ-NLS 303
Query 295 VNLVSLITFGHRIHGIIEGDSDLDTFLPELIQHYQAGKFPFDKLIKK-YALSEINQAIQD 353
+N + L+T G G I G +P+L+ + A KF D LI +IN+
Sbjct 304 MNPMLLLT-GRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDL 362
Query 354 QAQGRCIKAVLI 365
G+ I+ +L+
Sbjct 363 LHSGKSIRTILM 374
Lambda K H a alpha
0.322 0.139 0.415 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1057518
Database: 4c842222e76cd8bb60edfad3f5f9291c.SwissProt.fasta
Posted date: May 14, 2024 12:52 PM
Number of letters in database: 3,684
Number of sequences in database: 10
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
