Comparative Genomics

ACIAD1622 / SwissProt Alignments

BLASTP 2.12.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: b1886f8ecd90c75bca17c8e876e2393a.SwissProt.fasta
           16 sequences; 5,156 total letters



Query= ACIAD1622

Length=320
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q47129 Transcriptional activator FeaR [Escherichia coli (strain K...  65.1    2e-15
Q9Z3Q6 Transcriptional activator RhrA [Rhizobium meliloti (strain...  55.5    4e-12
G3XCU2 HTH-type transcriptional regulator ArgR [Pseudomonas aerug...  53.9    1e-11
P55449 Uncharacterized HTH-type transcriptional regulator y4fK [S...  53.9    2e-11
Q05092 XylDLEGF operon transcriptional activator 2 [Pseudomonas p...  48.9    2e-10
Q04710 XylDLEGF operon transcriptional activator 1 [Pseudomonas p...  50.1    3e-10
P07859 XylDLEGF operon transcriptional activator [Pseudomonas put...  50.1    3e-10
Q04713 XylDLEGF operon transcriptional activator 1 [Pseudomonas p...  45.8    6e-09
Q05335 XylDLEGF operon transcriptional activator 3 [Pseudomonas p...  45.1    1e-08
B7LVD8 HTH-type transcriptional activator RhaS [Escherichia fergu...  44.7    1e-08
P68912 Uncharacterized HTH-type transcriptional regulator Mb1430 ...  40.0    5e-07
P9WMJ1 Uncharacterized HTH-type transcriptional regulator Rv1395 ...  40.0    5e-07
P9WMJ0 Uncharacterized HTH-type transcriptional regulator MT1440 ...  40.0    5e-07
Q9HTI4 HTH-type transcriptional regulator GbdR [Pseudomonas aerug...  38.1    2e-06
A0A0H2ZIC3 HTH-type transcriptional regulator GbdR [Pseudomonas a...  38.1    2e-06
P17410 HTH-type transcriptional regulator ChbR [Escherichia coli ...  36.6    6e-06


>Q47129 Transcriptional activator FeaR [Escherichia coli (strain 
K12)]
Length=301

 Score = 65.1 bits (157),  Expect = 2e-15
 Identities = 72/286 (25%), Positives = 131/286 (46%), Gaps = 24/286 (8%)

Query  46   NFNGEL-NVRHVGLID--------ICTVSSTMHFWERTEKHLRTGPNDDLWLG--FMEDG  94
            NF G L   R+ G++D        + TV+++     RT + ++   +DD W    F   G
Sbjct  22   NFTGRLLTERYTGVLDTHFAKGLKLSTVTTSGVNLSRTWQEVKG--SDDAWFYTVFQLSG  79

Query  95   NGELVQGGRGTKYQNNSLMLYDAAQTFK-FNLSGQKNHLIRIPRHLLANRVPNIEQLTAQ  153
               + Q  R  +     + L DA++    +     K   + +PR LL    P+ + + A+
Sbjct  80   QAIMEQDERQVQIGAGDITLLDASRPCSLYWQESSKQISLLLPRTLLEQYFPHQKPICAE  139

Query  154  VLDESRPGIIPLREMLRQSVDATYDFSNIDFAERFTKSALELLVLSLE--VQDLSKVAIE  211
             LD   P +     +L++S++      N   +E  +++AL+ +V  L   +     V   
Sbjct  140  RLDADLPMVQLSHRLLQESMN------NPALSETESEAALQAMVCLLRPVLHQRESVQPR  193

Query  212  RDL-YSKAMNFILRHLCDPELNLEKVAQAHCVSVRTLSRAFARHQKTVMSVIWSERLNAS  270
            R+  + K +  I  ++ +  L  E +A    +SVR+L R FA     V   I + RL+  
Sbjct  194  RERQFQKVVTLIDDNIREEILRPEWIAGETGMSVRSLYRMFADKGLVVAQYIRNRRLDFC  253

Query  271  REALK-SGRVTSVSEAALDYGFTDFSHFSHAFKKAFGISPREDFKK  315
             +A++ +     ++     +GF+D SHFS  FK+ FG++P E  +K
Sbjct  254  ADAIRHAADDEKLAGIGFHWGFSDQSHFSTVFKQRFGMTPGEYRRK  299


>Q9Z3Q6 Transcriptional activator RhrA [Rhizobium meliloti (strain 
1021)]
Length=314

 Score = 55.5 bits (132),  Expect = 4e-12
 Identities = 31/127 (24%), Positives = 67/127 (53%), Gaps = 5/127 (4%)

Query  197  VLSLEVQDLSKVAIERDLYSKAMNFILR---HLCDPELNLEKVAQAHCVSVRTLSRAFAR  253
            +L +  QD+  V+     +++  +  +R   +L +   ++  VA+A  ++ R + + F+R
Sbjct  188  LLPVLAQDIGNVSPRETPHNRMASIKMRVEQNLANGSFSITDVAEAERITPRAIQKFFSR  247

Query  254  HQKTVMSVIWSERLNASREA-LKSGRVTSVSEAALDYGFTDFSHFSHAFKKAFGISPRED  312
               T    +   RL+ ++   L  G  TS+S+ A + GF D S+F+  F+  +G+ P  D
Sbjct  248  EGTTFSRYVLGRRLSLAKSLILAEGEATSISQIAYNVGFNDLSYFNRTFRSRYGVRP-SD  306

Query  313  FKKLSSS  319
             ++L+++
Sbjct  307  LRRLAAA  313


>G3XCU2 HTH-type transcriptional regulator ArgR [Pseudomonas aeruginosa 
(strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 
14847 / LMG 12228 / 1C / PRS 101 / PAO1)]
Length=329

 Score = 53.9 bits (128),  Expect = 1e-11
 Identities = 32/83 (39%), Positives = 47/83 (57%), Gaps = 2/83 (2%)

Query  231  LNLEKVAQAHCVSVRTLSRAFARHQKTVMSVIWSE-RLNASREALKSGRVTSVSEAALDY  289
            L  +++AQ  CVS R L R F ++   V S  + E RLN +R+ L      S+ +  L  
Sbjct  228  LTTDEIAQHVCVSRRQLERIFKQYLNRVPSQYYLELRLNRARQMLMQTS-KSIIQIGLSC  286

Query  290  GFTDFSHFSHAFKKAFGISPRED  312
            GF+   HFS A++  FG++PRED
Sbjct  287  GFSSGPHFSSAYRNFFGVTPRED  309


>P55449 Uncharacterized HTH-type transcriptional regulator y4fK 
[Sinorhizobium fredii (strain NBRC 101917 / NGR234)]
Length=427

 Score = 53.9 bits (128),  Expect = 2e-11
 Identities = 34/94 (36%), Positives = 57/94 (61%), Gaps = 2/94 (2%)

Query  217  KAMNFILRHLCDPELNLEKVAQAHCVSVRTLSRAFARHQK-TVMSVIWSERLNASREALK  275
            KA  F+  +L +P + +E +A A   + R L R F  ++  + MSV+ + RL A+  A+K
Sbjct  319  KAEAFMRENLTNP-VTIEDLAAAARCTPRALQRMFRTYRGGSPMSVLCNYRLAAAHGAIK  377

Query  276  SGRVTSVSEAALDYGFTDFSHFSHAFKKAFGISP  309
            +GR  S++E AL+  F++   FS  +K A+G+SP
Sbjct  378  AGRAGSITELALNLQFSNPGRFSVLYKSAYGLSP  411


>Q05092 XylDLEGF operon transcriptional activator 2 [Pseudomonas 
putida]
Length=157

 Score = 48.9 bits (115),  Expect = 2e-10
 Identities = 36/131 (27%), Positives = 65/131 (50%), Gaps = 5/131 (4%)

Query  185  AERFTKSALELLVLSLEVQDLSKVAIERD-LYSKAMNFILRHLCDPELNLEKVAQAHCVS  243
            AE +TK     L+ +L      K  +E +  + + + FI  ++    ++LE++A+   +S
Sbjct  7    AEHYTKIIATKLLETLSSNVSRKGFVEGNPCFERVVQFIEENV-KRSISLEQLAELALMS  65

Query  244  VRTLSRAFARHQKTV-MSVIWSERLNASREALKSG--RVTSVSEAALDYGFTDFSHFSHA  300
             R+L   F +H  T  M+ I + +L   R  L +    + S++E ALDYGF     F+  
Sbjct  66   PRSLYTMFEKHTGTTPMNYIRNRKLECVRACLSNPTTNIRSITEVALDYGFLHLGRFAEK  125

Query  301  FKKAFGISPRE  311
            ++  FG  P +
Sbjct  126  YRSTFGELPSD  136


>Q04710 XylDLEGF operon transcriptional activator 1 [Pseudomonas 
putida]
Length=321

 Score = 50.1 bits (118),  Expect = 3e-10
 Identities = 34/116 (29%), Positives = 60/116 (52%), Gaps = 11/116 (9%)

Query  210  IERDLYSKA-------MNFILRHLCDPELNLEKVAQAHCVSVRTLSRAFARHQKTV-MSV  261
            + R+++SK        + FI  +L    ++LE++A+   +S R+L   F +H  T   + 
Sbjct  201  VSREIFSKGNPSFERVVQFIEENL-KRNISLERLAELAMMSPRSLYNLFEKHAGTTPKNY  259

Query  262  IWSERLNASREALK--SGRVTSVSEAALDYGFTDFSHFSHAFKKAFGISPREDFKK  315
            I + +L + R  L   S  V S++E ALDYGF     F+  ++ AFG  P +  ++
Sbjct  260  IRNRKLESIRACLNDPSANVRSITEIALDYGFLHLGRFAENYRSAFGELPSDTLRQ  315


>P07859 XylDLEGF operon transcriptional activator [Pseudomonas 
putida]
Length=321

 Score = 50.1 bits (118),  Expect = 3e-10
 Identities = 34/116 (29%), Positives = 60/116 (52%), Gaps = 11/116 (9%)

Query  210  IERDLYSKA-------MNFILRHLCDPELNLEKVAQAHCVSVRTLSRAFARHQKTV-MSV  261
            + R+++SK        + FI  +L    ++LE++A+   +S R+L   F +H  T   + 
Sbjct  201  VSREIFSKGNPSFERVVQFIEENL-KRNISLERLAELAMMSPRSLYNLFEKHAGTTPKNY  259

Query  262  IWSERLNASREALK--SGRVTSVSEAALDYGFTDFSHFSHAFKKAFGISPREDFKK  315
            I + +L + R  L   S  V S++E ALDYGF     F+  ++ AFG  P +  ++
Sbjct  260  IRNRKLESIRACLNDPSANVRSITEIALDYGFLHLGRFAENYRSAFGELPSDTLRQ  315


>Q04713 XylDLEGF operon transcriptional activator 1 [Pseudomonas 
putida]
Length=331

 Score = 45.8 bits (107),  Expect = 6e-09
 Identities = 33/116 (28%), Positives = 58/116 (50%), Gaps = 11/116 (9%)

Query  210  IERDLYSKA-------MNFILRHLCDPELNLEKVAQAHCVSVRTLSRAFARHQKTV-MSV  261
            + R+++SK        + FI  +L    ++LE++A+   +S R+L   F +H  T   + 
Sbjct  201  VSREIFSKGNPSFERVVQFIEENL-KRNISLERLAELALMSPRSLYTLFEKHAGTTPKNY  259

Query  262  IWSERLNASREALK--SGRVTSVSEAALDYGFTDFSHFSHAFKKAFGISPREDFKK  315
            I + +L   R  L   +  V SV+E ALDYGF     F+  ++  FG  P +  ++
Sbjct  260  IRNRKLECIRARLSDPNANVRSVTEMALDYGFFHTGRFAENYRSTFGELPSDTLRR  315


>Q05335 XylDLEGF operon transcriptional activator 3 [Pseudomonas 
putida]
Length=331

 Score = 45.1 bits (105),  Expect = 1e-08
 Identities = 30/104 (29%), Positives = 53/104 (51%), Gaps = 4/104 (4%)

Query  215  YSKAMNFILRHLCDPELNLEKVAQAHCVSVRTLSRAFARHQKTV-MSVIWSERLNASREA  273
            + + + FI  +L    ++LE++A+   +S R+L   F +H  T   + I + +L   R  
Sbjct  213  FERVVQFIEDNL-KQSISLERLAELALMSPRSLYTLFEKHAGTTPKNYIRNRKLECIRAR  271

Query  274  LK--SGRVTSVSEAALDYGFTDFSHFSHAFKKAFGISPREDFKK  315
            L   +  V SV+E ALDYGF     F+  ++  FG  P +  ++
Sbjct  272  LSDPNANVRSVTEMALDYGFFHTGRFAENYRSTFGELPSDTLRR  315


>B7LVD8 HTH-type transcriptional activator RhaS [Escherichia fergusonii 
(strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 
14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 
0568-73)]
Length=278

 Score = 44.7 bits (104),  Expect = 1e-08
 Identities = 39/123 (32%), Positives = 59/123 (48%), Gaps = 6/123 (5%)

Query  194  ELLVLSLEVQDLSKVAIERDLYSKA-MNFILRHLCD---PELNLEKVAQAHCVSVRTLSR  249
            E+L + L V       +E D  + A +N ++  L D     ++ E +A    +S+RTL R
Sbjct  147  EILFMQLLVALRKNSLLEGDENTDARLNHLIAWLEDHFAEAVSWEAIADRFALSLRTLHR  206

Query  250  AFARHQK-TVMSVIWSERLNASREALKSGRVTSVSEAALDYGFTDFSHFSHAFKKAFGIS  308
               +H   T    +   RL  +R  L+     SV+  A   GF D +HFS  F++ FG S
Sbjct  207  QLKQHTGLTPQRYLNRLRLVKARHLLRHSD-DSVTHIAFSCGFADSNHFSTLFRREFGWS  265

Query  309  PRE  311
            PRE
Sbjct  266  PRE  268


>P68912 Uncharacterized HTH-type transcriptional regulator Mb1430 
[Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)]
Length=344

 Score = 40.0 bits (92),  Expect = 5e-07
 Identities = 21/67 (31%), Positives = 38/67 (57%), Gaps = 1/67 (1%)

Query  245  RTLSRAFARHQKTVMSVIWSERLNASREALKSGRVTSVSEAALDYGFTDFSHFSHAFKKA  304
            RTL R  A    +  +++   R   + + L++  +T V + +   G+T+ S FSHAFK+ 
Sbjct  274  RTLRRRLAEEGTSFRALLGEARSTVAVDLLRNVGLT-VQQVSTRLGYTEVSTFSHAFKRW  332

Query  305  FGISPRE  311
            +G++P E
Sbjct  333  YGVAPSE  339


>P9WMJ1 Uncharacterized HTH-type transcriptional regulator Rv1395 
[Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)]
Length=344

 Score = 40.0 bits (92),  Expect = 5e-07
 Identities = 21/67 (31%), Positives = 38/67 (57%), Gaps = 1/67 (1%)

Query  245  RTLSRAFARHQKTVMSVIWSERLNASREALKSGRVTSVSEAALDYGFTDFSHFSHAFKKA  304
            RTL R  A    +  +++   R   + + L++  +T V + +   G+T+ S FSHAFK+ 
Sbjct  274  RTLRRRLAEEGTSFRALLGEARSTVAVDLLRNVGLT-VQQVSTRLGYTEVSTFSHAFKRW  332

Query  305  FGISPRE  311
            +G++P E
Sbjct  333  YGVAPSE  339


>P9WMJ0 Uncharacterized HTH-type transcriptional regulator MT1440 
[Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)]
Length=344

 Score = 40.0 bits (92),  Expect = 5e-07
 Identities = 21/67 (31%), Positives = 38/67 (57%), Gaps = 1/67 (1%)

Query  245  RTLSRAFARHQKTVMSVIWSERLNASREALKSGRVTSVSEAALDYGFTDFSHFSHAFKKA  304
            RTL R  A    +  +++   R   + + L++  +T V + +   G+T+ S FSHAFK+ 
Sbjct  274  RTLRRRLAEEGTSFRALLGEARSTVAVDLLRNVGLT-VQQVSTRLGYTEVSTFSHAFKRW  332

Query  305  FGISPRE  311
            +G++P E
Sbjct  333  YGVAPSE  339


>Q9HTI4 HTH-type transcriptional regulator GbdR [Pseudomonas aeruginosa 
(strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 
14847 / LMG 12228 / 1C / PRS 101 / PAO1)]
Length=367

 Score = 38.1 bits (87),  Expect = 2e-06
 Identities = 27/83 (33%), Positives = 45/83 (54%), Gaps = 2/83 (2%)

Query  231  LNLEKVAQAHCVSVRTLSRAFARHQKTVMSVIWSE-RLNASREALKSGRVTSVSEAALDY  289
            ++L+++A    VS R L R F ++     S  + + RL  +R+ LK   + S+ E A   
Sbjct  241  IDLDELAVYVNVSRRQLERLFQKYLHCSPSRYYLKLRLIRARQLLKQTSM-SIIEVASVC  299

Query  290  GFTDFSHFSHAFKKAFGISPRED  312
            GF    HFS  +++ FGI PR++
Sbjct  300  GFVSTPHFSKCYREYFGIPPRDE  322


 Score = 18.1 bits (35),  Expect = 4.6
 Identities = 7/30 (23%), Positives = 14/30 (47%), Gaps = 0/30 (0%)

Query  56   VGLIDICTVSSTMHFWERTEKHLRTGPNDD  85
            + +  +C   ST HF +   ++    P D+
Sbjct  293  IEVASVCGFVSTPHFSKCYREYFGIPPRDE  322


>A0A0H2ZIC3 HTH-type transcriptional regulator GbdR [Pseudomonas 
aeruginosa (strain UCBPP-PA14)]
Length=367

 Score = 38.1 bits (87),  Expect = 2e-06
 Identities = 27/83 (33%), Positives = 45/83 (54%), Gaps = 2/83 (2%)

Query  231  LNLEKVAQAHCVSVRTLSRAFARHQKTVMSVIWSE-RLNASREALKSGRVTSVSEAALDY  289
            ++L+++A    VS R L R F ++     S  + + RL  +R+ LK   + S+ E A   
Sbjct  241  IDLDELAVYVNVSRRQLERLFQKYLHCSPSRYYLKLRLIRARQLLKQTSM-SIIEVASVC  299

Query  290  GFTDFSHFSHAFKKAFGISPRED  312
            GF    HFS  +++ FGI PR++
Sbjct  300  GFVSTPHFSKCYREYFGIPPRDE  322


 Score = 18.1 bits (35),  Expect = 4.6
 Identities = 7/30 (23%), Positives = 14/30 (47%), Gaps = 0/30 (0%)

Query  56   VGLIDICTVSSTMHFWERTEKHLRTGPNDD  85
            + +  +C   ST HF +   ++    P D+
Sbjct  293  IEVASVCGFVSTPHFSKCYREYFGIPPRDE  322


>P17410 HTH-type transcriptional regulator ChbR [Escherichia coli 
(strain K12)]
Length=280

 Score = 36.6 bits (83),  Expect = 6e-06
 Identities = 28/89 (31%), Positives = 45/89 (51%), Gaps = 2/89 (2%)

Query  230  ELNLEKVAQAHCVSVRTLSRAFARHQ-KTVMSVIWSERLNASREALKSGRVTSVSEAALD  288
            E  LE +      S   L+RA  R+  KT M +I   R+N +++ L+     SV++ A +
Sbjct  189  ESALENMVALSAKSQEYLTRATQRYYGKTPMQIINEIRINFAKKQLEMTNY-SVTDIAFE  247

Query  289  YGFTDFSHFSHAFKKAFGISPREDFKKLS  317
             G++  S F   FKK    +P+   KKL+
Sbjct  248  AGYSSPSLFIKTFKKLTSFTPKSYRKKLT  276



Lambda      K        H        a         alpha
   0.322    0.135    0.401    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 1211080


  Database: b1886f8ecd90c75bca17c8e876e2393a.SwissProt.fasta
    Posted date:  May 20, 2024  2:12 PM
  Number of letters in database: 5,156
  Number of sequences in database:  16



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40