BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 7f2c8b0fb572f3af15728f4af6c64956.SwissProt.fasta
18 sequences; 6,329 total letters
Query= ACIAD1630
Length=400
Score E
Sequences producing significant alignments: (Bits) Value
O53732 Tuberculostearic acid methyltransferase UfaA1 [Mycobacteri... 225 5e-73
P31049 Probable fatty acid methyltransferase [Pseudomonas putida] 175 5e-54
P0A9H8 Cyclopropane-fatty-acyl-phospholipid synthase [Escherichia... 172 4e-53
P0A9H7 Cyclopropane-fatty-acyl-phospholipid synthase [Escherichia... 172 4e-53
P9WPB0 Mycolic acid methyltransferase MmaA1 [Mycobacterium tuberc... 132 3e-39
P9WPB1 Mycolic acid methyltransferase MmaA1 [Mycobacterium tuberc... 132 3e-39
A5U030 Mycolic acid methyltransferase MmaA1 [Mycobacterium tuberc... 132 3e-39
P0A5Q1 Mycolic acid methyltransferase MmaA1 [Mycobacterium bovis ... 132 3e-39
P9WPB4 Cyclopropane mycolic acid synthase 2 [Mycobacterium tuberc... 132 5e-39
P0A5P1 Cyclopropane mycolic acid synthase 2 [Mycobacterium bovis ... 132 5e-39
P9WPB5 Cyclopropane mycolic acid synthase 2 [Mycobacterium tuberc... 132 5e-39
Q6MX39 S-adenosylmethionine-dependent methyltransferase UmaA [Myc... 128 2e-37
Q5APD4 Sphingolipid C9-methyltransferase [Candida albicans (strai... 132 2e-37
I1RNL0 Sphingolipid C9-methyltransferase 2 [Gibberella zeae (stra... 131 4e-37
I1RJD6 Sphingolipid C9-methyltransferase 1 [Gibberella zeae (stra... 129 3e-36
P9WPB7 Cyclopropane mycolic acid synthase 1 [Mycobacterium tuberc... 124 4e-36
A5U866 Cyclopropane mycolic acid synthase 1 [Mycobacterium tuberc... 124 4e-36
P9WPB3 Cyclopropane mycolic acid synthase 3 [Mycobacterium tuberc... 124 5e-36
>O53732 Tuberculostearic acid methyltransferase UfaA1 [Mycobacterium
tuberculosis (strain ATCC 25618 / H37Rv)]
Length=427
Score = 225 bits (574), Expect = 5e-73
Identities = 133/362 (37%), Positives = 203/362 (56%), Gaps = 14/362 (4%)
Query 36 GTVGEASDLHA-IIDVHNP-ALMQLIFKNGVLGAAEGYIRGDWTTEQLVELIQILSRNRD 93
GT A+D A + +H P AL + I ++G++G E Y+ G+W++++L ++ +L+ + D
Sbjct 57 GTATGAADPRAPSLFIHRPDALARRIGRHGLIGFGESYMAGEWSSKELTRVLTVLAGSVD 116
Query 94 VMDKLNQNVVAQASQAVLKVWYKSRQNSLSGSQKNIADHYDLSNDFFKLFLDESMMYSSA 153
+ + + + + W +S +++NIA HYDLSND F FLDE+M YS A
Sbjct 117 ELVPRSLHWLRPITPTFRPSW---PDHSRDQARRNIAVHYDLSNDLFAAFLDETMTYSCA 173
Query 154 IFEN-------DSMSLEAASDLKKERICQKLQLKPLDHLVEIGSGWGGFAIYAAQNYGCQ 206
+F + L AA K +R+ ++ H++EIG+GWG I AA G
Sbjct 174 MFTDLLAQPTPAWTELAAAQRRKIDRLLDVAGVQQGSHVLEIGTGWGELCIRAAAR-GAH 232
Query 207 VTTITISQAQYDEAVARVNAAGLSHRVNVQLKDYRLLEGKFDKLVSIEMIEAVGEQYLPT 266
+ ++T+S Q A RV AAG HRV + L DYR ++G++D +VS+EMIEAVG + P
Sbjct 233 IRSVTLSVEQQRLARQRVAAAGFGHRVEIDLCDYRDVDGQYDSVVSVEMIEAVGYRSWPR 292
Query 267 YFNQCRNLLKPHGLALIQAITIEDARYQKALNTVDFIKRYIFPGSFIPSISVLTQRASEQ 326
YF L++P G IQAIT+ R +T +I++YIFPG +PS + +
Sbjct 293 YFAALEQLVRPGGPVAIQAITMPHHRMLATRHTQTWIQKYIFPGGLLPSTQAIIDITGQH 352
Query 327 K-LRLKQLDDIGLSYAKTLHHWRERFLAQKDQVLALGFDENFIRMWDFYLCYCEGGFKEG 385
LR+ + YA+TL WRERF+ ++D + LGFDE F RMW+ YL Y E GF+ G
Sbjct 353 TGLRIVDAASLRPHYAETLRLWRERFMQRRDGLAHLGFDEVFARMWELYLAYSEAGFRSG 412
Query 386 VI 387
+
Sbjct 413 YL 414
>P31049 Probable fatty acid methyltransferase [Pseudomonas putida]
Length=394
Score = 175 bits (443), Expect = 5e-54
Identities = 101/275 (37%), Positives = 155/275 (56%), Gaps = 7/275 (3%)
Query 129 IADHYDLSNDFFKLFLDESMMYSSAIFENDSMSLEAASDLKKERICQKLQLKPLDHLVEI 188
I+ HYD+SN F++L+LD+ M YS A F +L+ A K + +C+KL+L D+L+++
Sbjct 107 ISYHYDVSNAFYQLWLDQDMAYSCAYFREPDNTLDQAQQDKFDHLCRKLRLNAGDYLLDV 166
Query 189 GSGWGGFAIYAAQNYGCQVTTITISQAQYDEAVARVNAAGLSHRVNVQLKDYRLL--EGK 246
G GWGG A +AA+ Y +V IT+S+ Q RV A GL+ +V++Q+ DYR L +G+
Sbjct 167 GCGWGGLARFAAREYDAKVFGITLSKEQLKLGRQRVKAEGLTDKVDLQILDYRDLPQDGR 226
Query 247 FDKLVSIEMIEAVGEQYLPTYFNQCRNLLKPHGLALIQAITIE--DARYQKALNTVDFIK 304
FDK+VS+ M E VG L Y + ++ GL + IT + D R +FI
Sbjct 227 FDKVVSVGMFEHVGHANLALYCQKLFGAVREGGLVMNHGITAKHVDGR-PVGRGAGEFID 285
Query 305 RYIFPGSFIPSISVLTQRASEQKLRLKQLDDIGLSYAKTLHHWRERFLAQKDQVLALGFD 364
RY+FP +P +S+++ E L + ++ + L YAKTLHHW E Q + AL
Sbjct 286 RYVFPHGELPHLSMISASICEAGLEVVDVESLRLHYAKTLHHWSENLENQLHKAAAL-VP 344
Query 365 ENFIRMWDFYLCYCEGGFKEGVISDVHMLFEASAY 399
E +R+W YL C F++G I ++H + Y
Sbjct 345 EKTLRIWRLYLAGCAYAFEKGWI-NLHQILAVKPY 378
>P0A9H8 Cyclopropane-fatty-acyl-phospholipid synthase [Escherichia
coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)]
Length=382
Score = 172 bits (436), Expect = 4e-53
Identities = 119/340 (35%), Positives = 172/340 (51%), Gaps = 19/340 (6%)
Query 46 AIIDVHNPALMQLIFKNGVLGAAEGYIRGDWTTEQLVELIQILSRNRDVMDKLNQNVVAQ 105
A I V NP + + + G LG E Y+ G W ++L V+ +N +
Sbjct 37 ADIRVKNPDFFKRVLQEGSLGLGESYMDGWWECDRLDMFFS------KVLRAGLENQLPH 90
Query 106 ASQAVLKVWYKSRQNSLSGSQKNIA--DHYDLSNDFFKLFLDESMMYSSAIFENDSMSLE 163
+ L++ N S + I +HYDL ND F LD M YS A ++ D+ +LE
Sbjct 91 HFKDTLRIAGARLFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWK-DADNLE 149
Query 164 AASDLKKERICQKLQLKPLDHLVEIGSGWGGFAIYAAQNYGCQVTTITISQAQYDEAVAR 223
+A K + IC+KLQLKP +++IG GWGG A Y A NY V +TIS Q + +A+
Sbjct 150 SAQQAKLKMICEKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQ--QKMAQ 207
Query 224 VNAAGLSHRVNVQLKDYRLLEGKFDKLVSIEMIEAVGEQYLPTYFNQCRNLLKPHGLALI 283
GL V + L+DYR L +FD++VS+ M E VG + TYF LKP G+ L+
Sbjct 208 ERCEGLD--VTILLQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFAVVDRNLKPEGIFLL 265
Query 284 QAITIEDARYQKALNTVDFIKRYIFPGSFIPSISVLTQRASEQKLRLKQLDDIGLSYAKT 343
I + LN +I +YIFP +PS+ + Q +SE ++ + G Y T
Sbjct 266 HTI----GSKKTDLNVDPWINKYIFPNGCLPSVRQIAQ-SSEPHFVMEDWHNFGADYDTT 320
Query 344 LHHWRERFLAQKDQVLALGFDENFIRMWDFYLCYCEGGFK 383
L W ERFLA ++ A + E F RM+ +YL C G F+
Sbjct 321 LMAWYERFLAAWPEI-ADNYSERFKRMFTYYLNACAGAFR 359
>P0A9H7 Cyclopropane-fatty-acyl-phospholipid synthase [Escherichia
coli (strain K12)]
Length=382
Score = 172 bits (436), Expect = 4e-53
Identities = 119/340 (35%), Positives = 172/340 (51%), Gaps = 19/340 (6%)
Query 46 AIIDVHNPALMQLIFKNGVLGAAEGYIRGDWTTEQLVELIQILSRNRDVMDKLNQNVVAQ 105
A I V NP + + + G LG E Y+ G W ++L V+ +N +
Sbjct 37 ADIRVKNPDFFKRVLQEGSLGLGESYMDGWWECDRLDMFFS------KVLRAGLENQLPH 90
Query 106 ASQAVLKVWYKSRQNSLSGSQKNIA--DHYDLSNDFFKLFLDESMMYSSAIFENDSMSLE 163
+ L++ N S + I +HYDL ND F LD M YS A ++ D+ +LE
Sbjct 91 HFKDTLRIAGARLFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWK-DADNLE 149
Query 164 AASDLKKERICQKLQLKPLDHLVEIGSGWGGFAIYAAQNYGCQVTTITISQAQYDEAVAR 223
+A K + IC+KLQLKP +++IG GWGG A Y A NY V +TIS Q + +A+
Sbjct 150 SAQQAKLKMICEKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQ--QKMAQ 207
Query 224 VNAAGLSHRVNVQLKDYRLLEGKFDKLVSIEMIEAVGEQYLPTYFNQCRNLLKPHGLALI 283
GL V + L+DYR L +FD++VS+ M E VG + TYF LKP G+ L+
Sbjct 208 ERCEGLD--VTILLQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFAVVDRNLKPEGIFLL 265
Query 284 QAITIEDARYQKALNTVDFIKRYIFPGSFIPSISVLTQRASEQKLRLKQLDDIGLSYAKT 343
I + LN +I +YIFP +PS+ + Q +SE ++ + G Y T
Sbjct 266 HTI----GSKKTDLNVDPWINKYIFPNGCLPSVRQIAQ-SSEPHFVMEDWHNFGADYDTT 320
Query 344 LHHWRERFLAQKDQVLALGFDENFIRMWDFYLCYCEGGFK 383
L W ERFLA ++ A + E F RM+ +YL C G F+
Sbjct 321 LMAWYERFLAAWPEI-ADNYSERFKRMFTYYLNACAGAFR 359
>P9WPB0 Mycolic acid methyltransferase MmaA1 [Mycobacterium tuberculosis
(strain CDC 1551 / Oshkosh)]
Length=286
Score = 132 bits (333), Expect = 3e-39
Identities = 79/268 (29%), Positives = 134/268 (50%), Gaps = 16/268 (6%)
Query 133 YDLSNDFFKLFLDESMMYSSAIFENDSMSLEAASDLKKERICQKLQLKPLDHLVEIGSGW 192
YD+S+DFF LFLD + +Y+ A FE D M+LE A K + KL L+P L+++G GW
Sbjct 15 YDISDDFFALFLDPTWVYTCAYFERDDMTLEEAQLAKVDLALDKLNLEPGMTLLDVGCGW 74
Query 193 GGFAIYAAQNYGCQVTTITISQAQYDEAVARVNAAGLSHRVNVQLKDYRLLEGKFDKLVS 252
GG + A + Y V +T+S+ Y+ + R+ A G R +L+ + E D++VS
Sbjct 75 GGALVRAVEKYDVNVIGLTLSRNHYERSKDRLAAIGTQRRAEARLQGWEEFEENVDRIVS 134
Query 253 IEMIEAVGEQYLPTYFNQCRNLLKPHGLALIQAITIEDARY---------QKALNTVDFI 303
E +A ++ T+F + ++L G L+ ++ D R+ L + F+
Sbjct 135 FEAFDAFKKERYLTFFERSYDILPDDGRMLLHSLFTYDRRWLHEQGIALTMSDLRFLKFL 194
Query 304 KRYIFPGSFIPSISVLTQRASEQKLRLKQLDDIGLSYAKTLHHWRERFLAQKDQVLALGF 363
+ IFPG +PS + A ++ + + YA+TL W A +++ +A+
Sbjct 195 RESIFPGGELPSEPDIVDNAQAAGFTIEHVQLLQQHYARTLDAWAANLQAARERAIAVQS 254
Query 364 DE---NFIRMWDFYLCYCEGGFKEGVIS 388
+E NF+ YL C F+ G+I+
Sbjct 255 EEVYNNFMH----YLTGCAERFRRGLIN 278
>P9WPB1 Mycolic acid methyltransferase MmaA1 [Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv)]
Length=286
Score = 132 bits (333), Expect = 3e-39
Identities = 79/268 (29%), Positives = 134/268 (50%), Gaps = 16/268 (6%)
Query 133 YDLSNDFFKLFLDESMMYSSAIFENDSMSLEAASDLKKERICQKLQLKPLDHLVEIGSGW 192
YD+S+DFF LFLD + +Y+ A FE D M+LE A K + KL L+P L+++G GW
Sbjct 15 YDISDDFFALFLDPTWVYTCAYFERDDMTLEEAQLAKVDLALDKLNLEPGMTLLDVGCGW 74
Query 193 GGFAIYAAQNYGCQVTTITISQAQYDEAVARVNAAGLSHRVNVQLKDYRLLEGKFDKLVS 252
GG + A + Y V +T+S+ Y+ + R+ A G R +L+ + E D++VS
Sbjct 75 GGALVRAVEKYDVNVIGLTLSRNHYERSKDRLAAIGTQRRAEARLQGWEEFEENVDRIVS 134
Query 253 IEMIEAVGEQYLPTYFNQCRNLLKPHGLALIQAITIEDARY---------QKALNTVDFI 303
E +A ++ T+F + ++L G L+ ++ D R+ L + F+
Sbjct 135 FEAFDAFKKERYLTFFERSYDILPDDGRMLLHSLFTYDRRWLHEQGIALTMSDLRFLKFL 194
Query 304 KRYIFPGSFIPSISVLTQRASEQKLRLKQLDDIGLSYAKTLHHWRERFLAQKDQVLALGF 363
+ IFPG +PS + A ++ + + YA+TL W A +++ +A+
Sbjct 195 RESIFPGGELPSEPDIVDNAQAAGFTIEHVQLLQQHYARTLDAWAANLQAARERAIAVQS 254
Query 364 DE---NFIRMWDFYLCYCEGGFKEGVIS 388
+E NF+ YL C F+ G+I+
Sbjct 255 EEVYNNFMH----YLTGCAERFRRGLIN 278
>A5U030 Mycolic acid methyltransferase MmaA1 [Mycobacterium tuberculosis
(strain ATCC 25177 / H37Ra)]
Length=286
Score = 132 bits (333), Expect = 3e-39
Identities = 79/268 (29%), Positives = 134/268 (50%), Gaps = 16/268 (6%)
Query 133 YDLSNDFFKLFLDESMMYSSAIFENDSMSLEAASDLKKERICQKLQLKPLDHLVEIGSGW 192
YD+S+DFF LFLD + +Y+ A FE D M+LE A K + KL L+P L+++G GW
Sbjct 15 YDISDDFFALFLDPTWVYTCAYFERDDMTLEEAQLAKVDLALDKLNLEPGMTLLDVGCGW 74
Query 193 GGFAIYAAQNYGCQVTTITISQAQYDEAVARVNAAGLSHRVNVQLKDYRLLEGKFDKLVS 252
GG + A + Y V +T+S+ Y+ + R+ A G R +L+ + E D++VS
Sbjct 75 GGALVRAVEKYDVNVIGLTLSRNHYERSKDRLAAIGTQRRAEARLQGWEEFEENVDRIVS 134
Query 253 IEMIEAVGEQYLPTYFNQCRNLLKPHGLALIQAITIEDARY---------QKALNTVDFI 303
E +A ++ T+F + ++L G L+ ++ D R+ L + F+
Sbjct 135 FEAFDAFKKERYLTFFERSYDILPDDGRMLLHSLFTYDRRWLHEQGIALTMSDLRFLKFL 194
Query 304 KRYIFPGSFIPSISVLTQRASEQKLRLKQLDDIGLSYAKTLHHWRERFLAQKDQVLALGF 363
+ IFPG +PS + A ++ + + YA+TL W A +++ +A+
Sbjct 195 RESIFPGGELPSEPDIVDNAQAAGFTIEHVQLLQQHYARTLDAWAANLQAARERAIAVQS 254
Query 364 DE---NFIRMWDFYLCYCEGGFKEGVIS 388
+E NF+ YL C F+ G+I+
Sbjct 255 EEVYNNFMH----YLTGCAERFRRGLIN 278
>P0A5Q1 Mycolic acid methyltransferase MmaA1 [Mycobacterium bovis
(strain ATCC BAA-935 / AF2122/97)]
Length=286
Score = 132 bits (333), Expect = 3e-39
Identities = 79/268 (29%), Positives = 134/268 (50%), Gaps = 16/268 (6%)
Query 133 YDLSNDFFKLFLDESMMYSSAIFENDSMSLEAASDLKKERICQKLQLKPLDHLVEIGSGW 192
YD+S+DFF LFLD + +Y+ A FE D M+LE A K + KL L+P L+++G GW
Sbjct 15 YDISDDFFALFLDPTWVYTCAYFERDDMTLEEAQLAKVDLALDKLNLEPGMTLLDVGCGW 74
Query 193 GGFAIYAAQNYGCQVTTITISQAQYDEAVARVNAAGLSHRVNVQLKDYRLLEGKFDKLVS 252
GG + A + Y V +T+S+ Y+ + R+ A G R +L+ + E D++VS
Sbjct 75 GGALVRAVEKYDVNVIGLTLSRNHYERSKDRLAAIGTQRRAEARLQGWEEFEENVDRIVS 134
Query 253 IEMIEAVGEQYLPTYFNQCRNLLKPHGLALIQAITIEDARY---------QKALNTVDFI 303
E +A ++ T+F + ++L G L+ ++ D R+ L + F+
Sbjct 135 FEAFDAFKKERYLTFFERSYDILPDDGRMLLHSLFTYDRRWLHEQGIALTMSDLRFLKFL 194
Query 304 KRYIFPGSFIPSISVLTQRASEQKLRLKQLDDIGLSYAKTLHHWRERFLAQKDQVLALGF 363
+ IFPG +PS + A ++ + + YA+TL W A +++ +A+
Sbjct 195 RESIFPGGELPSEPDIVDNAQAAGFTIEHVQLLQQHYARTLDAWAANLQAARERAIAVQS 254
Query 364 DE---NFIRMWDFYLCYCEGGFKEGVIS 388
+E NF+ YL C F+ G+I+
Sbjct 255 EEVYNNFMH----YLTGCAERFRRGLIN 278
>P9WPB4 Cyclopropane mycolic acid synthase 2 [Mycobacterium tuberculosis
(strain CDC 1551 / Oshkosh)]
Length=302
Score = 132 bits (333), Expect = 5e-39
Identities = 89/285 (31%), Positives = 136/285 (48%), Gaps = 25/285 (9%)
Query 117 SRQNSLSGSQ-----KNIADHYDLSNDFFKLFLDESMMYSSAIFENDSMSLEAASDLKKE 171
S+ ++ SG+Q + + HYD SN+FFKL+LD SM YS A FE M+LE A K++
Sbjct 3 SQGDTTSGTQLKPPVEAVRSHYDKSNEFFKLWLDPSMTYSCAYFERPDMTLEEAQYAKRK 62
Query 172 RICQKLQLKPLDHLVEIGSGWGGFAIYAAQNYGCQVTTITISQAQYDEAVARVNAAGLSH 231
KL L+P L++IG GWG +A Y V +T+S+ QY A +
Sbjct 63 LALDKLNLEPGMTLLDIGCGWGSTMRHAVAEYDVNVIGLTLSENQYAHDKAMFDEVDSPR 122
Query 232 RVNVQLKDYRLLEGKFDKLVSIEMIE-------AVGEQYLPTYFNQCRNLLKPHGLALIQ 284
R V+++ + + D++VS+ E G + T+F + NL G L+
Sbjct 123 RKEVRIQGWEEFDEPVDRIVSLGAFEHFADGAGDAGFERYDTFFKKFYNLTPDDGRMLLH 182
Query 285 AITIEDARYQKALNT---------VDFIKRYIFPGSFIPSISVLTQRASEQKLRLKQLDD 335
ITI D + L + FI IFPG +P IS + +S ++++
Sbjct 183 TITIPDKEEAQELGLTSPMSLLRFIKFILTEIFPGGRLPRISQVDYYSSNAGWKVERYHR 242
Query 336 IGLSYAKTLHHWRERFLAQKDQVLALGFDENFIRMWDFYLCYCEG 380
IG +Y TL+ W + A KD+ +AL E + D Y+ Y G
Sbjct 243 IGANYVPTLNAWADALQAHKDEAIALKGQETY----DIYMHYLRG 283
>P0A5P1 Cyclopropane mycolic acid synthase 2 [Mycobacterium bovis
(strain ATCC BAA-935 / AF2122/97)]
Length=302
Score = 132 bits (333), Expect = 5e-39
Identities = 89/285 (31%), Positives = 136/285 (48%), Gaps = 25/285 (9%)
Query 117 SRQNSLSGSQ-----KNIADHYDLSNDFFKLFLDESMMYSSAIFENDSMSLEAASDLKKE 171
S+ ++ SG+Q + + HYD SN+FFKL+LD SM YS A FE M+LE A K++
Sbjct 3 SQGDTTSGTQLKPPVEAVRSHYDKSNEFFKLWLDPSMTYSCAYFERPDMTLEEAQYAKRK 62
Query 172 RICQKLQLKPLDHLVEIGSGWGGFAIYAAQNYGCQVTTITISQAQYDEAVARVNAAGLSH 231
KL L+P L++IG GWG +A Y V +T+S+ QY A +
Sbjct 63 LALDKLNLEPGMTLLDIGCGWGSTMRHAVAEYDVNVIGLTLSENQYAHDKAMFDEVDSPR 122
Query 232 RVNVQLKDYRLLEGKFDKLVSIEMIE-------AVGEQYLPTYFNQCRNLLKPHGLALIQ 284
R V+++ + + D++VS+ E G + T+F + NL G L+
Sbjct 123 RKEVRIQGWEEFDEPVDRIVSLGAFEHFADGAGDAGFERYDTFFKKFYNLTPDDGRMLLH 182
Query 285 AITIEDARYQKALNT---------VDFIKRYIFPGSFIPSISVLTQRASEQKLRLKQLDD 335
ITI D + L + FI IFPG +P IS + +S ++++
Sbjct 183 TITIPDKEEAQELGLTSPMSLLRFIKFILTEIFPGGRLPRISQVDYYSSNAGWKVERYHR 242
Query 336 IGLSYAKTLHHWRERFLAQKDQVLALGFDENFIRMWDFYLCYCEG 380
IG +Y TL+ W + A KD+ +AL E + D Y+ Y G
Sbjct 243 IGANYVPTLNAWADALQAHKDEAIALKGQETY----DIYMHYLRG 283
>P9WPB5 Cyclopropane mycolic acid synthase 2 [Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv)]
Length=302
Score = 132 bits (333), Expect = 5e-39
Identities = 89/285 (31%), Positives = 136/285 (48%), Gaps = 25/285 (9%)
Query 117 SRQNSLSGSQ-----KNIADHYDLSNDFFKLFLDESMMYSSAIFENDSMSLEAASDLKKE 171
S+ ++ SG+Q + + HYD SN+FFKL+LD SM YS A FE M+LE A K++
Sbjct 3 SQGDTTSGTQLKPPVEAVRSHYDKSNEFFKLWLDPSMTYSCAYFERPDMTLEEAQYAKRK 62
Query 172 RICQKLQLKPLDHLVEIGSGWGGFAIYAAQNYGCQVTTITISQAQYDEAVARVNAAGLSH 231
KL L+P L++IG GWG +A Y V +T+S+ QY A +
Sbjct 63 LALDKLNLEPGMTLLDIGCGWGSTMRHAVAEYDVNVIGLTLSENQYAHDKAMFDEVDSPR 122
Query 232 RVNVQLKDYRLLEGKFDKLVSIEMIE-------AVGEQYLPTYFNQCRNLLKPHGLALIQ 284
R V+++ + + D++VS+ E G + T+F + NL G L+
Sbjct 123 RKEVRIQGWEEFDEPVDRIVSLGAFEHFADGAGDAGFERYDTFFKKFYNLTPDDGRMLLH 182
Query 285 AITIEDARYQKALNT---------VDFIKRYIFPGSFIPSISVLTQRASEQKLRLKQLDD 335
ITI D + L + FI IFPG +P IS + +S ++++
Sbjct 183 TITIPDKEEAQELGLTSPMSLLRFIKFILTEIFPGGRLPRISQVDYYSSNAGWKVERYHR 242
Query 336 IGLSYAKTLHHWRERFLAQKDQVLALGFDENFIRMWDFYLCYCEG 380
IG +Y TL+ W + A KD+ +AL E + D Y+ Y G
Sbjct 243 IGANYVPTLNAWADALQAHKDEAIALKGQETY----DIYMHYLRG 283
>Q6MX39 S-adenosylmethionine-dependent methyltransferase UmaA
[Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)]
Length=286
Score = 128 bits (321), Expect = 2e-37
Identities = 83/269 (31%), Positives = 135/269 (50%), Gaps = 22/269 (8%)
Query 133 YDLSNDFFKLFLDESMMYSSAIFENDSMSLEAASDLKKERICQKLQLKPLDHLVEIGSGW 192
YD+S++FF LFLD +M Y+ A FE + M+LE A + K + KL L+P L++IG GW
Sbjct 15 YDVSDEFFSLFLDPTMAYTCAYFEREDMTLEEAQNAKFDLALDKLHLEPGMTLLDIGCGW 74
Query 193 GGFAIYAAQNYGCQVTTITISQAQYDEAVARVNAAGLSHRVNVQLKDYRLLEGKFDKLVS 252
GG A +NY V IT+S+ Q++ + A++ V V+L+ + K D++VS
Sbjct 75 GGGLQRAIENYDVNVIGITLSRNQFEYSKAKLAKIPTERSVQVRLQGWDEFTDKVDRIVS 134
Query 253 IEMIEAVGEQYLPTYFNQCRNLLKPHGLALIQAI---------------TIEDARYQKAL 297
I EA + +F + ++L G L+ I T+ D R+ K
Sbjct 135 IGAFEAFKMERYAAFFERSYDILPDDGRMLLHTILTYTQKQMHEMGVKVTMSDVRFMK-- 192
Query 298 NTVDFIKRYIFPGSFIPSISVLTQRASEQKLRLKQLDDIGLSYAKTLHHWRERFLAQKDQ 357
FI IFPG +P+ + + A ++++ + YA+TL+ W A KD+
Sbjct 193 ----FIGEEIFPGGQLPAQEDIFKFAQAADFSVEKVQLLQQHYARTLNIWAANLEANKDR 248
Query 358 VLALGFDENFIRMWDFYLCYCEGGFKEGV 386
+AL +E + + YL CE F++G+
Sbjct 249 AIALQSEEIY-NKYMHYLTGCEHFFRKGI 276
>Q5APD4 Sphingolipid C9-methyltransferase [Candida albicans (strain
SC5314 / ATCC MYA-2876)]
Length=513
Score = 132 bits (332), Expect = 2e-37
Identities = 81/266 (30%), Positives = 135/266 (51%), Gaps = 11/266 (4%)
Query 120 NSLSGSQKNIADHYDLSNDFFKLFLDESMMYSSAIFENDSM--SLEAASDLKKERICQKL 177
+S S ++ + DHYD +DF+ FL M+Y+S + + + +LE D K + K+
Sbjct 192 HSQSQDEEQVRDHYDRGDDFYTWFLGPRMIYTSGVISDITREETLEELQDNKLTVMADKI 251
Query 178 QLKPLDHLVEIGSGWGGFAIYAAQNYGCQVTTITISQAQYDEAVARVNAAGL-SHRVNVQ 236
LK DH+++IG GWG + +A+ YG VT IT+ + Q + G+ S + +
Sbjct 252 DLKKGDHVLDIGCGWGTWTTFASSKYGANVTGITLGRNQTKWGNTLLKEYGIPSDQSRIV 311
Query 237 LKDYR------LLEGKFDKLVSIEMIEAVGEQYLPTYFNQCRNLLKPHGLALIQAITIED 290
DYR GK+DK+ S+EM E VG + L Y QCR+ L+ GL +Q +
Sbjct 312 CCDYRDAPKSSKPSGKYDKITSVEMAEHVGIRRLTAYLEQCRDALEDDGLLFLQYSGLRK 371
Query 291 ARYQKALNTVDFIKRYIFPGSFIPS-ISVLTQRASEQKLRLKQLDDIGLSYAKTLHHWRE 349
+ L F+ +YIFPG+ + +S + +D+IG+ Y+ TL W
Sbjct 372 NWQYEDLEWGLFMNKYIFPGADASTPLSFFASCMESVGFEIVSVDNIGVHYSATLWRWYR 431
Query 350 RFLAQKDQVLALGFDENFIRMWDFYL 375
++ KD+V+ + + R+W+F+L
Sbjct 432 NWIGNKDKVVN-KYGVKWYRIWEFFL 456
>I1RNL0 Sphingolipid C9-methyltransferase 2 [Gibberella zeae (strain
ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 /
PH-1)]
Length=521
Score = 131 bits (330), Expect = 4e-37
Identities = 77/262 (29%), Positives = 136/262 (52%), Gaps = 8/262 (3%)
Query 123 SGSQKNIADHYDLSNDFFKLFLDESMMYSSAIFE--NDSMSLEAASDLKKERICQKLQLK 180
S ++ + DHYD +DF+ FL M+Y+S I N +LE D K +C+K+ L
Sbjct 198 SQDEEQVRDHYDRGDDFYGWFLGPRMIYTSGIISDINREETLEELQDNKLTVVCEKIGLT 257
Query 181 PLDHLVEIGSGWGGFAIYAAQNYGCQVTTITISQAQYDEAVARVNAAGL-SHRVNVQLKD 239
D +++IG GWG A +A++ YG VT +T+ + Q + + G+ + + KD
Sbjct 258 KGDSMLDIGCGWGTLARFASEQYGANVTGVTLGRNQTAWGNSSMRKVGIPEEQSRIVCKD 317
Query 240 YRLLE---GKFDKLVSIEMIEAVGEQYLPTYFNQCRNLLKPHGLALIQAITIEDARYQKA 296
YR + G + K+ S+EM E VG ++ ++ Q ++L G+ +Q I A +
Sbjct 318 YRDIPVPVGGYKKITSLEMSEHVGIRHFSSFLKQVHDMLDDDGVFFLQYAGIRKAWQYED 377
Query 297 LNTVDFIKRYIFPGSFIPS-ISVLTQRASEQKLRLKQLDDIGLSYAKTLHHWRERFLAQK 355
L F+ +YIFPG+ + + + + +K +D IG+ Y+ TL W ++ +
Sbjct 378 LTWGLFMNKYIFPGADASTPLGWVVDKLEGTGFEIKHIDTIGVHYSATLWRWYRNWMDNR 437
Query 356 DQVLALGFDENFIRMWDFYLCY 377
D+V A + + + R+W+F+L Y
Sbjct 438 DKVEA-KYGKRWFRIWEFFLAY 458
>I1RJD6 Sphingolipid C9-methyltransferase 1 [Gibberella zeae (strain
ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 /
PH-1)]
Length=513
Score = 129 bits (324), Expect = 3e-36
Identities = 84/274 (31%), Positives = 141/274 (51%), Gaps = 17/274 (6%)
Query 123 SGSQKNIADHYDLSNDFFKLFLDESMMYSSAIFENDSM--SLEAASDLKKERICQKLQLK 180
S ++ + +YD ND + FL M+Y+S I + + +LE D K +C+K+ LK
Sbjct 201 SQDEEQVRTNYDSGNDHYAWFLGPRMIYTSGIISDPTREETLEEMQDNKLAIVCEKISLK 260
Query 181 PLDHLVEIGSGWGGFAIYAAQNYGCQVTTITISQAQYDEAVARVNAAGL-SHRVNVQLKD 239
D L++IG GWG A +A+ NYG +VT +T+++ Q + AG+ + + D
Sbjct 261 EGDTLLDIGCGWGTLAKFASLNYGAKVTGVTLARNQVQWGNDGLQQAGIPEEQSRLLCCD 320
Query 240 YRLL--EGKFDKLVSIEMIEAVGEQYLPTYFNQCRNLLKPHGLALIQAITIEDARYQKAL 297
YR + + KF+K+ +EM E VG + L +F QC ++L+ G +Q + ++KA
Sbjct 321 YRDIPEDQKFNKITQLEMAEHVGVRRLTGFFRQCYDMLENDGSMYVQV-----SGFRKAW 375
Query 298 NTVDFI-----KRYIFPGSFIPS-ISVLTQRASEQKLRLKQLDDIGLSYAKTLHHWRERF 351
DFI +YIFPG+ + +S +K +D IG+ Y+ TL W +
Sbjct 376 QYEDFIWGLFLNKYIFPGADASTPLSYYVGCLESAGFEVKSVDTIGVHYSGTLWRWYRNW 435
Query 352 LAQKDQVLALGFDENFIRMWDFYLCYCEGGFKEG 385
L D+V A + + R+W+ +L Y G ++G
Sbjct 436 LGNADKVKA-KYGVRWFRIWEIFLAYSTIGSRQG 468
>P9WPB7 Cyclopropane mycolic acid synthase 1 [Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv)]
Length=287
Score = 124 bits (312), Expect = 4e-36
Identities = 85/269 (32%), Positives = 127/269 (47%), Gaps = 10/269 (4%)
Query 128 NIADHYDLSNDFFKLFLDESMMYSSAIFENDSMSLEAASDLKKERICQKLQLKPLDHLVE 187
N+ HYDLS+DFF+LFLD + YS A FE D M+L+ A K + KL L+P L++
Sbjct 11 NVQAHYDLSDDFFRLFLDPTQTYSCAYFERDDMTLQEAQIAKIDLALGKLGLQPGMTLLD 70
Query 188 IGSGWGGFAIYAAQNYGCQVTTITISQAQYDEAVARVNAAGLSHRVNVQLKDYRLLEGKF 247
+G GWG + A + Y V +T+S+ Q + V + V L + +
Sbjct 71 VGCGWGATMMRAVEKYDVNVVGLTLSKNQANHVQQLVANSENLRSKRVLLAGWEQFDEPV 130
Query 248 DKLVSIEMIEAVGEQYLPTYFNQCRNLLKPHGLALIQAIT------IEDARYQKALNTVD 301
D++VSI E G + +F+ LL G+ L+ IT I + +
Sbjct 131 DRIVSIGAFEHFGHERYDAFFSLAHRLLPADGVMLLHTITGLHPKEIHERGLPMSFTFAR 190
Query 302 FIK---RYIFPGSFIPSISVLTQRASEQKLRLKQLDDIGLSYAKTLHHWRERFLAQKDQV 358
F+K IFPG +PSI ++ + AS + ++ + YAKTL W A K Q
Sbjct 191 FLKFIVTEIFPGGRLPSIPMVQECASANGFTVTRVQSLQPHYAKTLDLWSAALQANKGQA 250
Query 359 LALGFDENFIRMWDFYLCYCEGGFKEGVI 387
+AL +E + R YL C F+ G I
Sbjct 251 IALQSEEVYERYMK-YLTGCAEMFRIGYI 278
>A5U866 Cyclopropane mycolic acid synthase 1 [Mycobacterium tuberculosis
(strain ATCC 25177 / H37Ra)]
Length=287
Score = 124 bits (312), Expect = 4e-36
Identities = 85/269 (32%), Positives = 127/269 (47%), Gaps = 10/269 (4%)
Query 128 NIADHYDLSNDFFKLFLDESMMYSSAIFENDSMSLEAASDLKKERICQKLQLKPLDHLVE 187
N+ HYDLS+DFF+LFLD + YS A FE D M+L+ A K + KL L+P L++
Sbjct 11 NVQAHYDLSDDFFRLFLDPTQTYSCAYFERDDMTLQEAQIAKIDLALGKLGLQPGMTLLD 70
Query 188 IGSGWGGFAIYAAQNYGCQVTTITISQAQYDEAVARVNAAGLSHRVNVQLKDYRLLEGKF 247
+G GWG + A + Y V +T+S+ Q + V + V L + +
Sbjct 71 VGCGWGATMMRAVEKYDVNVVGLTLSKNQANHVQQLVANSENLRSKRVLLAGWEQFDEPV 130
Query 248 DKLVSIEMIEAVGEQYLPTYFNQCRNLLKPHGLALIQAIT------IEDARYQKALNTVD 301
D++VSI E G + +F+ LL G+ L+ IT I + +
Sbjct 131 DRIVSIGAFEHFGHERYDAFFSLAHRLLPADGVMLLHTITGLHPKEIHERGLPMSFTFAR 190
Query 302 FIK---RYIFPGSFIPSISVLTQRASEQKLRLKQLDDIGLSYAKTLHHWRERFLAQKDQV 358
F+K IFPG +PSI ++ + AS + ++ + YAKTL W A K Q
Sbjct 191 FLKFIVTEIFPGGRLPSIPMVQECASANGFTVTRVQSLQPHYAKTLDLWSAALQANKGQA 250
Query 359 LALGFDENFIRMWDFYLCYCEGGFKEGVI 387
+AL +E + R YL C F+ G I
Sbjct 251 IALQSEEVYERYMK-YLTGCAEMFRIGYI 278
>P9WPB3 Cyclopropane mycolic acid synthase 3 [Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv)]
Length=287
Score = 124 bits (311), Expect = 5e-36
Identities = 83/267 (31%), Positives = 125/267 (47%), Gaps = 10/267 (4%)
Query 128 NIADHYDLSNDFFKLFLDESMMYSSAIFENDSMSLEAASDLKKERICQKLQLKPLDHLVE 187
N+ HYDLS+DFF+LFLD + YS A FE D M+L+ A K + KL L+P L++
Sbjct 11 NVQAHYDLSDDFFRLFLDPTQTYSCAYFERDDMTLQEAQIAKIDLALGKLNLEPGMTLLD 70
Query 188 IGSGWGGFAIYAAQNYGCQVTTITISQAQYDEAVARVNAAGLSHRVNVQLKDYRLLEGKF 247
IG GWG A + Y V +T+S+ Q + V L+ + +
Sbjct 71 IGCGWGATMRRAIEKYDVNVVGLTLSENQAGHVQKMFDQMDTPRSRRVLLEGWEKFDEPV 130
Query 248 DKLVSIEMIEAVGEQYLPTYFNQCRNLLKPHGLALIQAI---TIEDARYQ------KALN 298
D++VSI E G Q +F L G L+ I T ++ R + + ++
Sbjct 131 DRIVSIGAFEHFGHQRYHHFFEVTHRTLPADGKMLLHTIVRPTFKEGREKGLTLTHELVH 190
Query 299 TVDFIKRYIFPGSFIPSISVLTQRASEQKLRLKQLDDIGLSYAKTLHHWRERFLAQKDQV 358
FI IFPG ++PSI + + A + R+ + + L YA+TL W A KDQ
Sbjct 191 FTKFILAEIFPGGWLPSIPTVHEYAEKVGFRVTAVQSLQLHYARTLDMWATALEANKDQA 250
Query 359 LALGFDENFIRMWDFYLCYCEGGFKEG 385
+A+ + R YL C F++G
Sbjct 251 IAIQSQTVYDRYMK-YLTGCAKLFRQG 276
Lambda K H a alpha
0.323 0.138 0.410 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1900150
Database: 7f2c8b0fb572f3af15728f4af6c64956.SwissProt.fasta
Posted date: May 30, 2024 5:11 AM
Number of letters in database: 6,329
Number of sequences in database: 18
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
