BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: cffdca0a3ef76ff236851b3c6135b9c7.SwissProt.fasta
14 sequences; 5,558 total letters
Query= ACIAD1689
Length=402
Score E
Sequences producing significant alignments: (Bits) Value
Q43935 Beta-ketoadipyl-CoA thiolase [Acinetobacter baylyi (strain... 431 1e-153
Q43974 Beta-ketoadipyl-CoA thiolase [Acinetobacter baylyi (strain... 430 2e-153
P0C7L2 3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA thiolase [Esc... 429 4e-153
P0C7L3 Beta-ketoadipyl-CoA thiolase [Escherichia coli] 428 2e-152
Q9I6R0 Beta-ketoadipyl-CoA thiolase [Pseudomonas aeruginosa (stra... 415 2e-147
Q51956 Beta-ketoadipyl-CoA thiolase [Pseudomonas putida] 414 4e-147
Q8VPF1 Beta-ketoadipyl-CoA thiolase [Pseudomonas knackmussii (str... 399 3e-141
P76461 Acetyl-CoA acetyltransferase [Escherichia coli (strain K12)] 311 1e-106
Q9I2A8 Acetyl-CoA acetyltransferase [Pseudomonas aeruginosa (stra... 308 1e-105
P45369 Acetyl-CoA acetyltransferase [Allochromatium vinosum (stra... 304 6e-104
P14611 Acetyl-CoA acetyltransferase [Cupriavidus necator (strain ... 303 1e-103
P45359 Acetyl-CoA acetyltransferase [Clostridium acetobutylicum (... 302 3e-103
Q9ZHI1 Acetyl-CoA acetyltransferase [Chromobacterium violaceum (s... 301 6e-103
P45363 Acetyl-CoA acetyltransferase [Thiocystis violacea] 300 2e-102
>Q43935 Beta-ketoadipyl-CoA thiolase [Acinetobacter baylyi (strain
ATCC 33305 / BD413 / ADP1)]
Length=401
Score = 431 bits (1107), Expect = 1e-153
Identities = 229/402 (57%), Positives = 289/402 (72%), Gaps = 3/402 (1%)
Query 1 MLNAYIYDGLRTPFGRHAGELASIRPDDLAGLVIQRLIEKT-GVAGADIEDVIFGDTNQA 59
M +AYI D +RTPFGR+AG LA++R DDL + I LIE+ V A ++DVI+G NQA
Sbjct 1 MKHAYIVDAIRTPFGRYAGGLAAVRADDLGAIPIAALIERNPSVNWAQVDDVIYGCANQA 60
Query 60 GEDSRNIARHAALLAGLPVTVPGQTVNRLCASGLAAIIDSARAITCGEGDLYIAGGVESM 119
GED+RN+ R +ALLAGLPV VP TVNRLC S L AI +ARAI GE L IAGGVESM
Sbjct 61 GEDNRNVGRMSALLAGLPVEVPATTVNRLCGSSLDAIAMAARAIKAGEAHLIIAGGVESM 120
Query 120 SRAPFVMGKAESAYSRDAKIYDTTIGTRFPNKKIVAQYGGHSMPETGDNVAVEYGISREQ 179
SRAP+VMGK+E A+ R KI DTT+G RF N K+ A YG +MP+T +NVA ++GI RE
Sbjct 121 SRAPYVMGKSEGAFGRTQKIEDTTMGWRFINPKLKAMYGVDTMPQTAENVAEQFGIQRED 180
Query 180 ADLFAAQSQAKYQKALEEGFFAGEITAVEVSQGKKLPPKQVTEDEHPRPSSTLEALSKLK 239
D FA SQ + A +G+FA EI V + Q +K P + DEHPR S+TLE L+KLK
Sbjct 181 QDQFAYTSQQRTAAAQAKGYFAKEIVPVTIPQ-RKGEPVVIATDEHPRASTTLEGLAKLK 239
Query 240 PLFEG-GVVTAGNASGINDGAAALLIGSEVAGQKYGLTPMAKILSAAAAGVEPRIMGAGP 298
+ + G VTAGNASGINDGAAA+LI S+ A +Y L AKI+++ G+EPRIMG P
Sbjct 240 GVVKPEGSVTAGNASGINDGAAAVLIASDEAVAQYQLKARAKIIASTTVGIEPRIMGFAP 299
Query 299 IEAIKKAVARAGLTLDDLDIIEINEAFASQVLSCLKGLGIDFNDPRVNPNGGAIAVGHPL 358
AIKK + +A LTLD +D+IE+NEAFA+Q L+C + LG+ +D RVNPNGGAIA+GHPL
Sbjct 300 APAIKKLLKQANLTLDQMDVIELNEAFAAQALACTRDLGLADDDARVNPNGGAIALGHPL 359
Query 359 GASGARLALTVARELQRRNKKYAVVSLCIGVGQGLAMVIENV 400
GASGARL T +L++ KYA+ S+CIGVGQG+A++IE V
Sbjct 360 GASGARLVTTALNQLEQSGGKYALCSMCIGVGQGIALIIERV 401
>Q43974 Beta-ketoadipyl-CoA thiolase [Acinetobacter baylyi (strain
ATCC 33305 / BD413 / ADP1)]
Length=401
Score = 430 bits (1106), Expect = 2e-153
Identities = 229/402 (57%), Positives = 289/402 (72%), Gaps = 3/402 (1%)
Query 1 MLNAYIYDGLRTPFGRHAGELASIRPDDLAGLVIQRLIEKT-GVAGADIEDVIFGDTNQA 59
M +AYI D +RTPFGR+AG LA++R DDL + I LIE+ V A ++DVI+G NQA
Sbjct 1 MKHAYIVDAIRTPFGRYAGGLAAVRADDLGAIPIAALIERNPSVNWAQVDDVIYGCANQA 60
Query 60 GEDSRNIARHAALLAGLPVTVPGQTVNRLCASGLAAIIDSARAITCGEGDLYIAGGVESM 119
GED+RN+ R +ALLAGLPV VP TVNRLC S L AI +ARAI GE L IAGGVESM
Sbjct 61 GEDNRNVGRMSALLAGLPVEVPATTVNRLCGSSLDAIAMAARAIKAGEAHLIIAGGVESM 120
Query 120 SRAPFVMGKAESAYSRDAKIYDTTIGTRFPNKKIVAQYGGHSMPETGDNVAVEYGISREQ 179
SRAP+VMGK+E A+ R KI DTT+G RF N K+ A YG +MP+T +NVA ++GI RE
Sbjct 121 SRAPYVMGKSEGAFGRTQKIEDTTMGWRFINPKLKAMYGVDTMPQTAENVAEQFGIQRED 180
Query 180 ADLFAAQSQAKYQKALEEGFFAGEITAVEVSQGKKLPPKQVTEDEHPRPSSTLEALSKLK 239
D FA SQ + A +G+FA EI V + Q +K P + DEHPR S+TLE L+KLK
Sbjct 181 QDQFAYTSQQRTAAAQAKGYFAKEIVPVTIPQ-RKGEPVVIDTDEHPRASTTLEGLAKLK 239
Query 240 PLFEG-GVVTAGNASGINDGAAALLIGSEVAGQKYGLTPMAKILSAAAAGVEPRIMGAGP 298
+ + G VTAGNASGINDGAAA+LI S+ A +Y L AKI+++ G+EPRIMG P
Sbjct 240 GVVKPEGSVTAGNASGINDGAAAVLIASDEAVAQYQLKARAKIIASTTVGIEPRIMGFAP 299
Query 299 IEAIKKAVARAGLTLDDLDIIEINEAFASQVLSCLKGLGIDFNDPRVNPNGGAIAVGHPL 358
AIKK + +A LTLD +D+IE+NEAFA+Q L+C + LG+ +D RVNPNGGAIA+GHPL
Sbjct 300 APAIKKLLKQANLTLDQMDVIELNEAFAAQALACTRDLGLADDDARVNPNGGAIALGHPL 359
Query 359 GASGARLALTVARELQRRNKKYAVVSLCIGVGQGLAMVIENV 400
GASGARL T +L++ KYA+ S+CIGVGQG+A++IE V
Sbjct 360 GASGARLVTTALNQLEQSGGKYALCSMCIGVGQGIALIIERV 401
>P0C7L2 3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA thiolase
[Escherichia coli (strain K12)]
Length=401
Score = 429 bits (1104), Expect = 4e-153
Identities = 228/402 (57%), Positives = 289/402 (72%), Gaps = 3/402 (1%)
Query 1 MLNAYIYDGLRTPFGRHAGELASIRPDDLAGLVIQRLIEKTGVAGAD-IEDVIFGDTNQA 59
M A+I DG+RTP GR+ G L+S+R DDLA + ++ L+ + A+ I+DVI G NQA
Sbjct 1 MREAFICDGIRTPIGRYGGALSSVRADDLAAIPLRELLVRNPRLDAECIDDVILGCANQA 60
Query 60 GEDSRNIARHAALLAGLPVTVPGQTVNRLCASGLAAIIDSARAITCGEGDLYIAGGVESM 119
GED+RN+AR A LLAGLP +V G T+NRLC SGL A+ +ARAI G+GDL IAGGVESM
Sbjct 61 GEDNRNVARMATLLAGLPQSVSGTTINRLCGSGLDALGFAARAIKAGDGDLLIAGGVESM 120
Query 120 SRAPFVMGKAESAYSRDAKIYDTTIGTRFPNKKIVAQYGGHSMPETGDNVAVEYGISREQ 179
SRAPFVMGKA SA+SR A+++DTTIG RF N + Q+G SMPET +NVA ISRE
Sbjct 121 SRAPFVMGKAASAFSRQAEMFDTTIGWRFVNPLMAQQFGTDSMPETAENVAELLKISRED 180
Query 180 ADLFAAQSQAKYQKALEEGFFAGEITAVEVSQGKKLPPKQVTEDEHPRPSSTLEALSKLK 239
D FA +SQ + KA G A EI V V + KK ++ DEH RP +TLE L LK
Sbjct 181 QDSFALRSQQRTAKAQSSGILAEEIVPV-VLKNKKGVVTEIQHDEHLRPETTLEQLRGLK 239
Query 240 -PLFEGGVVTAGNASGINDGAAALLIGSEVAGQKYGLTPMAKILSAAAAGVEPRIMGAGP 298
P GV+TAGNASG+NDGAAAL+I SE GLTP A+I++ A AGVEPR+MG GP
Sbjct 240 APFRANGVITAGNASGVNDGAAALIIASEQMAAAQGLTPRARIVAMATAGVEPRLMGLGP 299
Query 299 IEAIKKAVARAGLTLDDLDIIEINEAFASQVLSCLKGLGIDFNDPRVNPNGGAIAVGHPL 358
+ A ++ + RAGL++ D+D+IE+NEAFA+Q L L+ LG+ + P VNPNGGAIA+GHPL
Sbjct 300 VPATRRVLERAGLSIHDMDVIELNEAFAAQALGVLRELGLPDDAPHVNPNGGAIALGHPL 359
Query 359 GASGARLALTVARELQRRNKKYAVVSLCIGVGQGLAMVIENV 400
G SGARLAL + EL RRN +YA+ ++CIGVGQG+AM++E V
Sbjct 360 GMSGARLALAASHELHRRNGRYALCTMCIGVGQGIAMILERV 401
>P0C7L3 Beta-ketoadipyl-CoA thiolase [Escherichia coli]
Length=401
Score = 428 bits (1100), Expect = 2e-152
Identities = 227/402 (56%), Positives = 288/402 (72%), Gaps = 3/402 (1%)
Query 1 MLNAYIYDGLRTPFGRHAGELASIRPDDLAGLVIQRLIEKTGVAGAD-IEDVIFGDTNQA 59
M A+I DG+RTP GR+ G L+ +R DDLA + ++ L+ + A+ I+DVI G NQA
Sbjct 1 MREAFICDGIRTPIGRYGGALSGVRADDLAAIPLRELLVRNPRLDAECIDDVILGCANQA 60
Query 60 GEDSRNIARHAALLAGLPVTVPGQTVNRLCASGLAAIIDSARAITCGEGDLYIAGGVESM 119
GED+RN+AR A LLAGLP +V G T+NRLC SGL A+ +ARAI G+GDL IAGGVESM
Sbjct 61 GEDNRNVARMATLLAGLPQSVSGTTINRLCGSGLDALGFAARAIKAGDGDLLIAGGVESM 120
Query 120 SRAPFVMGKAESAYSRDAKIYDTTIGTRFPNKKIVAQYGGHSMPETGDNVAVEYGISREQ 179
SRAPFVMGKA SA+SR A+++DTTIG RF N + Q+G SMPET +NVA ISRE
Sbjct 121 SRAPFVMGKATSAFSRQAEMFDTTIGWRFVNPLMAQQFGTDSMPETAENVAELLKISRED 180
Query 180 ADLFAAQSQAKYQKALEEGFFAGEITAVEVSQGKKLPPKQVTEDEHPRPSSTLEALSKLK 239
D FA +SQ + KA G A EI V V + KK ++ DEH RP +TLE L LK
Sbjct 181 QDSFALRSQQRTAKAQSSGILAEEIVPV-VLKNKKGVVTEIQHDEHLRPETTLEQLRGLK 239
Query 240 -PLFEGGVVTAGNASGINDGAAALLIGSEVAGQKYGLTPMAKILSAAAAGVEPRIMGAGP 298
P GV+TAGNASG+NDGAAAL+I SE GLTP A+I++ A AGVEPR+MG GP
Sbjct 240 APFRANGVITAGNASGVNDGAAALIIASEQMAAAQGLTPRARIVAMATAGVEPRLMGLGP 299
Query 299 IEAIKKAVARAGLTLDDLDIIEINEAFASQVLSCLKGLGIDFNDPRVNPNGGAIAVGHPL 358
+ A ++ + RAGL++ D+D+IE+NEAFA+Q L L+ LG+ + P VNPNGGAIA+GHPL
Sbjct 300 VPATRRVLERAGLSIHDMDVIELNEAFAAQALGVLRELGLPDDAPHVNPNGGAIALGHPL 359
Query 359 GASGARLALTVARELQRRNKKYAVVSLCIGVGQGLAMVIENV 400
G SGARLAL + EL RRN +YA+ ++CIGVGQG+AM++E V
Sbjct 360 GMSGARLALAASHELHRRNGRYALCTMCIGVGQGIAMILERV 401
>Q9I6R0 Beta-ketoadipyl-CoA thiolase [Pseudomonas aeruginosa (strain
ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG
12228 / 1C / PRS 101 / PAO1)]
Length=401
Score = 415 bits (1066), Expect = 2e-147
Identities = 219/398 (55%), Positives = 287/398 (72%), Gaps = 4/398 (1%)
Query 5 YIYDGLRTPFGRHAGELASIRPDDLAGLVIQRLIEKT-GVAGADIEDVIFGDTNQAGEDS 63
+I D +RTP GR G L+++R DDLA + ++ L+E+ GV + +++V G NQAGED+
Sbjct 6 FICDAVRTPIGRFGGSLSAVRADDLAAVPLKALVERNPGVDWSALDEVFLGCANQAGEDN 65
Query 64 RNIARHAALLAGLPVTVPGQTVNRLCASGLAAIIDSARAITCGEGDLYIAGGVESMSRAP 123
RN+AR A LLAGLP +VPG T+NRLCASG+ AI + RAI CGE +L IAGGVESMSRAP
Sbjct 66 RNVARMALLLAGLPESVPGVTLNRLCASGMDAIGTAFRAIACGEMELAIAGGVESMSRAP 125
Query 124 FVMGKAESAYSRDAKIYDTTIGTRFPNKKIVAQYGGHSMPETGDNVAVEYGISREQADLF 183
+VMGKA+SA+ R KI DTTIG RF N + QYG MP+T DNVA +Y +SR D F
Sbjct 126 YVMGKADSAFGRGQKIEDTTIGWRFVNPLMKEQYGIDPMPQTADNVADDYRVSRADQDAF 185
Query 184 AAQSQAKYQKALEEGFFAGEITAVEVSQGKKLPPKQVTEDEHPRPSSTLEALSKLKPLF- 242
A +SQ + +A E GFFA EI V + +G+K V DEHPRP +TLEAL++LKP+
Sbjct 186 ALRSQQRAGRAQEAGFFAEEIVPVTI-RGRK-GDTLVEHDEHPRPDTTLEALARLKPVNG 243
Query 243 EGGVVTAGNASGINDGAAALLIGSEVAGQKYGLTPMAKILSAAAAGVEPRIMGAGPIEAI 302
VTAGNASG+NDGAAAL++ S A +K+GLTP A++L A+AGV PRIMG GP+ A+
Sbjct 244 PEKTVTAGNASGVNDGAAALVLASAEAVEKHGLTPRARVLGMASAGVAPRIMGIGPVPAV 303
Query 303 KKAVARAGLTLDDLDIIEINEAFASQVLSCLKGLGIDFNDPRVNPNGGAIAVGHPLGASG 362
+K + R L +D D+IE+NEAFASQ L+CL+ LG+ + +VNPNGGAIA+GHPLG SG
Sbjct 304 RKLLRRLDLAIDAFDVIELNEAFASQGLACLRELGVADDSEKVNPNGGAIALGHPLGMSG 363
Query 363 ARLALTVARELQRRNKKYAVVSLCIGVGQGLAMVIENV 400
ARL LT +L++ + + ++C+GVGQGLA+ IE V
Sbjct 364 ARLVLTALHQLEKSGGRRGLATMCVGVGQGLALAIERV 401
>Q51956 Beta-ketoadipyl-CoA thiolase [Pseudomonas putida]
Length=400
Score = 414 bits (1064), Expect = 4e-147
Identities = 221/402 (55%), Positives = 282/402 (70%), Gaps = 4/402 (1%)
Query 1 MLNAYIYDGLRTPFGRHAGELASIRPDDLAGLVIQRLIEKTGVAGAD-IEDVIFGDTNQA 59
M + +I D +RTP GR G LA +R DDLA + ++ LIE D +++V FG NQA
Sbjct 1 MRDVFICDAIRTPIGRFGGALAGVRADDLAAVPLKALIEPNPAVQWDQVDEVFFGCANQA 60
Query 60 GEDSRNIARHAALLAGLPVTVPGQTVNRLCASGLAAIIDSARAITCGEGDLYIAGGVESM 119
GED+RN+AR A LLAGLP ++PG T+NRLCASG+ AI + RAI GE +L IAGGVESM
Sbjct 61 GEDNRNVARMALLLAGLPESIPGVTLNRLCASGMDAIGTAFRAIASGEMELAIAGGVESM 120
Query 120 SRAPFVMGKAESAYSRDAKIYDTTIGTRFPNKKIVAQYGGHSMPETGDNVAVEYGISREQ 179
SRAPFVMGKAES YSR+ K+ DTTIG RF N + +QYG SMPET DNVA +Y +SR
Sbjct 121 SRAPFVMGKAESGYSRNMKLEDTTIGWRFINPLMKSQYGVDSMPETADNVADDYQVSRAD 180
Query 180 ADLFAAQSQAKYQKALEEGFFAGEITAVEVSQGKKLPPKQVTEDEHPRPSSTLEALSKLK 239
D FA +SQ K A GFFA EI V ++ K V DEH RP +TLEAL+KLK
Sbjct 181 QDAFALRSQQKAAAAQAAGFFAEEIVPVRIAH--KKGETIVERDEHLRPETTLEALTKLK 238
Query 240 PL-FEGGVVTAGNASGINDGAAALLIGSEVAGQKYGLTPMAKILSAAAAGVEPRIMGAGP 298
P+ VTAGNASG+NDGAAAL++ S A +K+GLTP A++L A+ GV PR+MG GP
Sbjct 239 PVNGPDKTVTAGNASGVNDGAAALILASAEAVKKHGLTPRARVLGMASGGVAPRVMGIGP 298
Query 299 IEAIKKAVARAGLTLDDLDIIEINEAFASQVLSCLKGLGIDFNDPRVNPNGGAIAVGHPL 358
+ A++K R G+ + D D+IE+NEAFASQ L+ L+ LG+ + P+VNPNGGAIA+GHPL
Sbjct 299 VPAVRKLTERLGVAVSDFDVIELNEAFASQGLAVLRELGVADDAPQVNPNGGAIALGHPL 358
Query 359 GASGARLALTVARELQRRNKKYAVVSLCIGVGQGLAMVIENV 400
G SGARL LT +L++ + + ++C+GVGQGLA+ IE V
Sbjct 359 GMSGARLVLTALHQLEKSGGRKGLATMCVGVGQGLALAIERV 400
>Q8VPF1 Beta-ketoadipyl-CoA thiolase [Pseudomonas knackmussii
(strain DSM 6978 / LMG 23759 / B13)]
Length=401
Score = 399 bits (1026), Expect = 3e-141
Identities = 215/398 (54%), Positives = 282/398 (71%), Gaps = 4/398 (1%)
Query 5 YIYDGLRTPFGRHAGELASIRPDDLAGLVIQRLIEKTG-VAGADIEDVIFGDTNQAGEDS 63
YI D +RTP GR G LA++R DDLA + ++ L+E+ V + +++V G NQAGED+
Sbjct 6 YICDAVRTPIGRFGGSLAAVRADDLAAVPVKALVERNPQVDWSQLDEVYLGCANQAGEDN 65
Query 64 RNIARHAALLAGLPVTVPGQTVNRLCASGLAAIIDSARAITCGEGDLYIAGGVESMSRAP 123
RN+AR A LLAGLP +VPG T+NRLCASG+ A+ + RAI GE +L IAGGVESMSRAP
Sbjct 66 RNVARMALLLAGLPDSVPGVTLNRLCASGMDAVGTAFRAIASGEAELVIAGGVESMSRAP 125
Query 124 FVMGKAESAYSRDAKIYDTTIGTRFPNKKIVAQYGGHSMPETGDNVAVEYGISREQADLF 183
+VMGKA+SA+ R KI DTTIG RF N + AQYG +MPET DNVA +Y +SR D F
Sbjct 126 YVMGKADSAFGRGQKIEDTTIGWRFINPLMKAQYGVDAMPETADNVADDYKVSRADQDAF 185
Query 184 AAQSQAKYQKALEEGFFAGEITAVEVSQGKKLPPKQVTEDEHPRPSSTLEALSKLKPL-F 242
A +SQ +A G+FA EI V V +GKK V DEH RP +TLEAL+KLKP+
Sbjct 186 ALRSQQLAGRAQAAGYFAEEIVPV-VIKGKK-GETVVDADEHLRPDTTLEALAKLKPVNG 243
Query 243 EGGVVTAGNASGINDGAAALLIGSEVAGQKYGLTPMAKILSAAAAGVEPRIMGAGPIEAI 302
VTAGNASG+NDG+ AL++ S A +K+GL AK+L A+AGV PR+MG GP+ A+
Sbjct 244 PDKTVTAGNASGVNDGSVALILASAEAVKKHGLKARAKVLGMASAGVAPRVMGIGPVPAV 303
Query 303 KKAVARAGLTLDDLDIIEINEAFASQVLSCLKGLGIDFNDPRVNPNGGAIAVGHPLGASG 362
+K + R L++ D D+IE+NEAFA+Q L+ + LGI +D RVNPNGGAIA+GHPLGASG
Sbjct 304 RKLLERLNLSVADFDVIELNEAFAAQGLAVTRELGIADDDARVNPNGGAIALGHPLGASG 363
Query 363 ARLALTVARELQRRNKKYAVVSLCIGVGQGLAMVIENV 400
ARL LT +L++ + + ++C+GVGQG+A+ +E V
Sbjct 364 ARLVLTAVHQLEKSGGQRGLCTMCVGVGQGVALAVERV 401
>P76461 Acetyl-CoA acetyltransferase [Escherichia coli (strain
K12)]
Length=394
Score = 311 bits (796), Expect = 1e-106
Identities = 186/404 (46%), Positives = 250/404 (62%), Gaps = 13/404 (3%)
Query 1 MLNAYIYDGLRTPFGRHAGELASIRPDDLAGLVIQRLIEKTGVAGADIEDVIFGDTNQAG 60
M N I +RT G G LAS DL VI+ IE+ + +++VI G+ QAG
Sbjct 1 MKNCVIVSAVRTAIGSFNGSLASTSAIDLGATVIKAAIERAKIDSQHVDEVIMGNVLQAG 60
Query 61 EDSRNIARHAALLAGLPVTVPGQTVNRLCASGLAAIIDSARAITCGEGDLYIAGGVESMS 120
+N AR A L +GL TV G TVN++C SGL ++ +A+AI G+ +AGG+E+MS
Sbjct 61 L-GQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAIQAGQAQSIVAGGMENMS 119
Query 121 RAPFVM-GKAESAYSR-DAKIYDTTIGTRFPNKKIVAQYGGHSMPETGDNVAVEYGISRE 178
AP+++ KA S Y D ++YD + ++ G+ M T +NVA EYGI+RE
Sbjct 120 LAPYLLDAKARSGYRLGDGQVYDVIL-----RDGLMCATHGYHMGITAENVAKEYGITRE 174
Query 179 QADLFAAQSQAKYQKALEEGFFAGEITAVEVSQGKKLPPKQVTEDEHPRPSSTLEALSKL 238
D A SQ K A+E G F EI V V KK ++DE P+ +ST EAL L
Sbjct 175 MQDELALHSQRKAAAAIESGAFTAEIVPVNVVTRKKT--FVFSQDEFPKANSTAEALGAL 232
Query 239 KPLFE-GGVVTAGNASGINDGAAALLIGSEVAGQKYGLTPMAKILSAAAAGVEPRIMGAG 297
+P F+ G VTAGNASGINDGAAAL+I E A GLTP+A+I S A+ GV P +MG G
Sbjct 233 RPAFDKAGTVTAGNASGINDGAAALVIMEESAALAAGLTPLARIKSYASGGVPPALMGMG 292
Query 298 PIEAIKKAVARAGLTLDDLDIIEINEAFASQVLSCLKGLGIDFNDPRVNPNGGAIAVGHP 357
P+ A +KA+ AGL L D+D+IE NEAFA+Q L+ K LG F+ +VN NGGAIA+GHP
Sbjct 293 PVPATQKALQLAGLQLADIDLIEANEAFAAQFLAVGKNLG--FDSEKVNVNGGAIALGHP 350
Query 358 LGASGARLALTVARELQRRNKKYAVVSLCIGVGQGLAMVIENVS 401
+GASGAR+ +T+ +Q R+K + +LCIG GQG+AMVIE ++
Sbjct 351 IGASGARILVTLLHAMQARDKTLGLATLCIGGGQGIAMVIERLN 394
>Q9I2A8 Acetyl-CoA acetyltransferase [Pseudomonas aeruginosa (strain
ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG
12228 / 1C / PRS 101 / PAO1)]
Length=393
Score = 308 bits (789), Expect = 1e-105
Identities = 180/399 (45%), Positives = 253/399 (63%), Gaps = 11/399 (3%)
Query 1 MLNAYIYDGLRTPFGRHAGELASIRPDDLAGLVIQRLIEKTGVAGADIEDVIFGDTNQAG 60
M + I RT G G LA I +L VI+RL+E+TG+ +++VI G AG
Sbjct 1 MQDVVIVAATRTAVGSFQGSLAGIPAPELGAAVIRRLLEQTGLDAGQVDEVILGQVLTAG 60
Query 61 EDSRNIARHAALLAGLPVTVPGQTVNRLCASGLAAIIDSARAITCGEGDLYIAGGVESMS 120
+N AR AA+ AGLPV VP T+N++C SGL A+ A+AI CG+ ++ +AGG E+MS
Sbjct 61 S-GQNPARQAAIKAGLPVGVPAMTLNKVCGSGLKALHLGAQAIRCGDAEVIVAGGQENMS 119
Query 121 RAPFVMGKAESAYSRD-AKIYDTTIGTRFPNKKIVAQYGGHSMPETGDNVAVEYGISREQ 179
AP+VM A + AK+ D+ I + + + M T +N+A +YG++RE+
Sbjct 120 LAPYVMPGARTGLRMGHAKLVDSMI-----EDGLWDAFNDYHMGITAENLAEKYGLTREE 174
Query 180 ADLFAAQSQAKYQKALEEGFFAGEITAVEVSQGKKLPPKQVTEDEHPRPSSTLEALSKLK 239
D FAA SQ K A+E G F EIT ++V Q +K P DE PR +T+EAL+KLK
Sbjct 175 QDAFAAASQQKAIAAIEGGRFRDEITPIQVPQ-RKGEPLGFDTDEQPRAGTTVEALAKLK 233
Query 240 PLF-EGGVVTAGNASGINDGAAALLIGSEVAGQKYGLTPMAKILSAAAAGVEPRIMGAGP 298
P F + G VTAGNAS +NDGAAA+L+ S + GL +A+I S A+AGV+P IMG GP
Sbjct 234 PAFRKDGSVTAGNASSLNDGAAAVLLMSAAKAKALGLPVLARIASYASAGVDPAIMGIGP 293
Query 299 IEAIKKAVARAGLTLDDLDIIEINEAFASQVLSCLKGLGIDFNDPRVNPNGGAIAVGHPL 358
+ A ++A+ +AG +L+ LD+IE NEAFA+Q L+ + LG D RVN NGGAIA+GHP+
Sbjct 294 VSATRRALDKAGWSLEQLDLIEANEAFAAQSLAVGRELGWD--AARVNVNGGAIALGHPI 351
Query 359 GASGARLALTVARELQRRNKKYAVVSLCIGVGQGLAMVI 397
GASG R+ +T+ E+ RR+ K + +LCIG GQG+A+ +
Sbjct 352 GASGCRVLVTLLHEMIRRDAKKGLATLCIGGGQGVALTL 390
>P45369 Acetyl-CoA acetyltransferase [Allochromatium vinosum (strain
ATCC 17899 / DSM 180 / NBRC 103801 / NCIMB 10441 / D)]
Length=394
Score = 304 bits (778), Expect = 6e-104
Identities = 173/400 (43%), Positives = 251/400 (63%), Gaps = 11/400 (3%)
Query 3 NAYIYDGLRTPFGRHAGELASIRPDDLAGLVIQRLIEKTGVAGADIEDVIFGDTNQAGED 62
N I D R+ G +G L+S+ ++ V++ L+ +TG+A I++VI G AG
Sbjct 4 NIVIVDAGRSAIGTFSGSLSSLSATEIGTAVLKGLLARTGLAPEQIDEVILGQVLTAGV- 62
Query 63 SRNIARHAALLAGLPVTVPGQTVNRLCASGLAAIIDSARAITCGEGDLYIAGGVESMSRA 122
+N AR L AGLP +VP T+N++C SGL A+ + +AI CG+ D+ IAGG ESMS++
Sbjct 63 GQNPARQTTLKAGLPHSVPAMTINKVCGSGLKAVHLAMQAIACGDADIVIAGGQESMSQS 122
Query 123 PFVMGKAESAYSR-DAKIYDTTIGTRFPNKKIVAQYGGHSMPETGDNVAVEYGISREQAD 181
V+ ++ D + DT I + + + M T +N+A +YG +REQ D
Sbjct 123 SHVLPRSRDGQRMGDWSMKDTMIVDGLWDA-----FNNYHMGTTAENIAQKYGFTREQQD 177
Query 182 LFAAQSQAKYQKALEEGFFAGEITAVEVSQGKKLPPKQVTEDEHPRPSSTLEALSKLKPL 241
FAA SQ K + A + G F EI +E+ Q +K PK DE PR +T E+L KL+P
Sbjct 178 AFAAASQQKTEAAQKAGRFQDEIIPIEIPQ-RKGDPKVFDADEFPRHGTTAESLGKLRPA 236
Query 242 FE-GGVVTAGNASGINDGAAALLIGSEVAGQKYGLTPMAKILSAAAAGVEPRIMGAGPIE 300
F G VTAGNASGINDGAA +++ E ++ GL PMA++++ A+AGV+P IMG GPI
Sbjct 237 FSRDGSVTAGNASGINDGAAMVVVMKESKAKELGLKPMARLVAFASAGVDPAIMGTGPIP 296
Query 301 AIKKAVARAGLTLDDLDIIEINEAFASQVLSCLKGLGIDFNDPRVNPNGGAIAVGHPLGA 360
A K + +AG T DLD+IE NEAFA+Q +S + +G D + +VN NGGAIA+GHP+GA
Sbjct 297 ASTKCLEKAGWTPADLDLIEANEAFAAQAMSVNQDMGWDLS--KVNVNGGAIAIGHPIGA 354
Query 361 SGARLALTVARELQRRNKKYAVVSLCIGVGQGLAMVIENV 400
SGAR+ +T+ E+Q+R+ K + +LCIG GQG+A+ +E +
Sbjct 355 SGARVLVTLLYEMQKRDAKKGLATLCIGGGQGVALAVERM 394
>P14611 Acetyl-CoA acetyltransferase [Cupriavidus necator (strain
ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 /
Stanier 337)]
Length=393
Score = 303 bits (776), Expect = 1e-103
Identities = 176/400 (44%), Positives = 248/400 (62%), Gaps = 11/400 (3%)
Query 1 MLNAYIYDGLRTPFGRHAGELASIRPDDLAGLVIQRLIEKTGVAGADIEDVIFGDTNQAG 60
M + I RT G+ G LA I +L +VI+ +E+ GV + +VI G AG
Sbjct 1 MTDVVIVSAARTAVGKFGGSLAKIPAPELGAVVIKAALERAGVKPEQVSEVIMGQVLTAG 60
Query 61 EDSRNIARHAALLAGLPVTVPGQTVNRLCASGLAAIIDSARAITCGEGDLYIAGGVESMS 120
+N AR AA+ AGLP VP T+N++C SGL A++ +A AI G+ ++ +AGG E+MS
Sbjct 61 S-GQNPARQAAIKAGLPAMVPAMTINKVCGSGLKAVMLAANAIMAGDAEIVVAGGQENMS 119
Query 121 RAPFVM-GKAESAYSRDAKIYDTTIGTRFPNKKIVAQYGGHSMPETGDNVAVEYGISREQ 179
AP V+ G + DAK+ DT I + Y + M T +NVA EYGI+RE
Sbjct 120 AAPHVLPGSRDGFRMGDAKLVDTMIVDGLWDV-----YNQYHMGITAENVAKEYGITREA 174
Query 180 ADLFAAQSQAKYQKALEEGFFAGEITAVEVSQGKKLPPKQVTEDEHPRPSSTLEALSKLK 239
D FA SQ K + A + G F EI V + Q +K P DE R +TL+++S LK
Sbjct 175 QDEFAVGSQNKAEAAQKAGKFDEEIVPVLIPQ-RKGDPVAFKTDEFVRQGATLDSMSGLK 233
Query 240 PLFE-GGVVTAGNASGINDGAAALLIGSEVAGQKYGLTPMAKILSAAAAGVEPRIMGAGP 298
P F+ G VTA NASG+NDGAAA+++ S ++ GLTP+A I S A AGV+P++MG GP
Sbjct 234 PAFDKAGTVTAANASGLNDGAAAVVVMSAAKAKELGLTPLATIKSYANAGVDPKVMGMGP 293
Query 299 IEAIKKAVARAGLTLDDLDIIEINEAFASQVLSCLKGLGIDFNDPRVNPNGGAIAVGHPL 358
+ A K+A++RA T DLD++EINEAFA+Q L+ + +G D + +VN NGGAIA+GHP+
Sbjct 294 VPASKRALSRAEWTPQDLDLMEINEAFAAQALAVHQQMGWDTS--KVNVNGGAIAIGHPI 351
Query 359 GASGARLALTVARELQRRNKKYAVVSLCIGVGQGLAMVIE 398
GASG R+ +T+ E++RR+ K + SLCIG G G+A+ +E
Sbjct 352 GASGCRILVTLLHEMKRRDAKKGLASLCIGGGMGVALAVE 391
>P45359 Acetyl-CoA acetyltransferase [Clostridium acetobutylicum
(strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)]
Length=392
Score = 302 bits (773), Expect = 3e-103
Identities = 175/400 (44%), Positives = 247/400 (62%), Gaps = 12/400 (3%)
Query 1 MLNAYIYDGLRTPFGRHAGELASIRPDDLAGLVIQRLIEKTGVAGADIEDVIFGDTNQAG 60
M I +RT G + L + DL I+ ++K G+ D+ +VI G+ QAG
Sbjct 1 MKEVVIASAVRTAIGSYGKSLKDVPAVDLGATAIKEAVKKAGIKPEDVNEVILGNVLQAG 60
Query 61 EDSRNIARHAALLAGLPVTVPGQTVNRLCASGLAAIIDSARAITCGEGDLYIAGGVESMS 120
+N AR A+ AGLPV +P T+N++C SGL + +A+ I G+ D+ IAGG+E+MS
Sbjct 61 L-GQNPARQASFKAGLPVEIPAMTINKVCGSGLRTVSLAAQIIKAGDADVIIAGGMENMS 119
Query 121 RAPFVMGKAESAYSR-DAKIYDTTIGTRFPNKKIVAQYGGHSMPETGDNVAVEYGISREQ 179
RAP++ A Y +AK D I + + + M T +N+A + ISRE+
Sbjct 120 RAPYLANNARWGYRMGNAKFVDEMI-----TDGLWDAFNDYHMGITAENIAERWNISREE 174
Query 180 ADLFAAQSQAKYQKALEEGFFAGEITAVEVSQGKKLPPKQVTEDEHPRPSSTLEALSKLK 239
D FA SQ K ++A++ G F EI V V +G+K V DEHPR ST+E L+KLK
Sbjct 175 QDEFALASQKKAEEAIKSGQFKDEIVPV-VIKGRK-GETVVDTDEHPRFGSTIEGLAKLK 232
Query 240 PLFE-GGVVTAGNASGINDGAAALLIGSEVAGQKYGLTPMAKILSAAAAGVEPRIMGAGP 298
P F+ G VTAGNASG+ND AA L+I S ++ G+ P+AKI+S +AGV+P IMG GP
Sbjct 233 PAFKKDGTVTAGNASGLNDCAAVLVIMSAEKAKELGVKPLAKIVSYGSAGVDPAIMGYGP 292
Query 299 IEAIKKAVARAGLTLDDLDIIEINEAFASQVLSCLKGLGIDFNDPRVNPNGGAIAVGHPL 358
A K A+ +AG T+D+LD+IE NEAFA+Q L+ K L D N +VN NGGAIA+GHP+
Sbjct 293 FYATKAAIEKAGWTVDELDLIESNEAFAAQSLAVAKDLKFDMN--KVNVNGGAIALGHPI 350
Query 359 GASGARLALTVARELQRRNKKYAVVSLCIGVGQGLAMVIE 398
GASGAR+ +T+ +Q+R+ K + +LCIG GQG A+++E
Sbjct 351 GASGARILVTLVHAMQKRDAKKGLATLCIGGGQGTAILLE 390
>Q9ZHI1 Acetyl-CoA acetyltransferase [Chromobacterium violaceum
(strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB
9131 / NCTC 9757)]
Length=392
Score = 301 bits (771), Expect = 6e-103
Identities = 174/390 (45%), Positives = 239/390 (61%), Gaps = 11/390 (3%)
Query 11 RTPFGRHAGELASIRPDDLAGLVIQRLIEKTGVAGADIEDVIFGDTNQAGEDSRNIARHA 70
RT G G LA I +L VI+ L+EKTGV D+ +VI G AG +N AR A
Sbjct 10 RTAIGSFGGGLAKIPAPELGATVIKALLEKTGVKPEDVSEVILGQVLTAGS-GQNPARQA 68
Query 71 ALLAGLPVTVPGQTVNRLCASGLAAIIDSARAITCGEGDLYIAGGVESMSRAPFVM-GKA 129
+ AGLPVT P T+N +C SGL A+ +A+AI G+ D+ IAGG ESMS +P ++ G
Sbjct 69 LIKAGLPVTTPATTLNVVCGSGLRAVHLAAQAILAGDADIVIAGGQESMSLSPHILPGSR 128
Query 130 ESAYSRDAKIYDTTIGTRFPNKKIVAQYGGHSMPETGDNVAVEYGISREQADLFAAQSQA 189
+ +A++ DT + N + Y + M T +NVA +YGI RE+ D F+ QSQ
Sbjct 129 DGFRMGNAQLVDTMV-----NDGLTDAYNAYHMGITAENVAAKYGIGREEQDAFSLQSQQ 183
Query 190 KYQKALEEGFFAGEITAVEVSQGKKLPPKQVTEDEHPRPSSTLEALSKLKPLFE-GGVVT 248
+ A + G F EI V V Q +K P DE + ++ + L+KL+P F+ G VT
Sbjct 184 RAAAAQKAGKFRDEIVPVLVPQ-RKGDPLAFDADEFIKHDASADGLAKLRPAFKKDGTVT 242
Query 249 AGNASGINDGAAALLIGSEVAGQKYGLTPMAKILSAAAAGVEPRIMGAGPIEAIKKAVAR 308
AGNASGINDGAAA+L+ S + GL P+A I A G EP IMG GP+ A +KA+++
Sbjct 243 AGNASGINDGAAAVLLMSTQKADQLGLKPLAIIKGYALTGCEPEIMGIGPVSATRKALSK 302
Query 309 AGLTLDDLDIIEINEAFASQVLSCLKGLGIDFNDPRVNPNGGAIAVGHPLGASGARLALT 368
AG T++DLD++E NEAFA+Q L K LG + +VN NGGAIA+GHP+GASG R+ +T
Sbjct 303 AGWTVEDLDLVEANEAFAAQALGVAKELG--WGSDKVNVNGGAIALGHPIGASGCRVLVT 360
Query 369 VARELQRRNKKYAVVSLCIGVGQGLAMVIE 398
+ E+QRR K + +LCIG G G+A+ +E
Sbjct 361 LLHEMQRRGAKKGLATLCIGGGMGVALAVE 390
>P45363 Acetyl-CoA acetyltransferase [Thiocystis violacea]
Length=394
Score = 300 bits (768), Expect = 2e-102
Identities = 169/397 (43%), Positives = 249/397 (63%), Gaps = 11/397 (3%)
Query 6 IYDGLRTPFGRHAGELASIRPDDLAGLVIQRLIEKTGVAGADIEDVIFGDTNQAGEDSRN 65
I D RT G G L++++ D+ V++ LIE+TG+A + +VI G AG +N
Sbjct 7 IVDAGRTAIGTFGGALSALQATDIGTTVLKALIERTGIAPEQVSEVILGQVLTAG-CGQN 65
Query 66 IARHAALLAGLPVTVPGQTVNRLCASGLAAIIDSARAITCGEGDLYIAGGVESMSRAPFV 125
AR L+AGLP TVP T+N++C SGL A+ + +A+ CG+ ++ IAGG ESMS++ V
Sbjct 66 PARQTTLMAGLPHTVPAMTINKVCGSGLKAVHLAMQAVACGDAEIVIAGGQESMSQSSHV 125
Query 126 MGKA-ESAYSRDAKIYDTTIGTRFPNKKIVAQYGGHSMPETGDNVAVEYGISREQADLFA 184
+ ++ E D + DT I + + M T +N+A +Y +RE D FA
Sbjct 126 LPRSREGQRMGDWPMKDTMIVDGLWDA-----FNQCHMGVTAENIAKKYAFTREAQDAFA 180
Query 185 AQSQAKYQKALEEGFFAGEITAVEVSQGKKLPPKQVTEDEHPRPSSTLEALSKLKPLFEG 244
A SQ K + A++ G FA EI V + Q +K P DE PRP +T E L +L+P F+
Sbjct 181 AASQQKAEAAIQSGRFADEIIPVSIPQ-RKGDPLVFDTDEFPRPGTTAETLGRLRPAFDK 239
Query 245 -GVVTAGNASGINDGAAALLIGSEVAGQKYGLTPMAKILSAAAAGVEPRIMGAGPIEAIK 303
G VTAGNASGINDGAA +++ E ++ GLTPMA++++ ++AGV+P IMG GPI A
Sbjct 240 QGTVTAGNASGINDGAAMVVVMKESKAKELGLTPMARLVAFSSAGVDPAIMGTGPIPAST 299
Query 304 KAVARAGLTLDDLDIIEINEAFASQVLSCLKGLGIDFNDPRVNPNGGAIAVGHPLGASGA 363
+ +AG DLD++E NEAFA+Q +S + +G D + +VN NGGAIA+GHP+GASGA
Sbjct 300 DCLKKAGWAPADLDLVEANEAFAAQAMSVNQEMGWDLS--KVNVNGGAIAIGHPIGASGA 357
Query 364 RLALTVARELQRRNKKYAVVSLCIGVGQGLAMVIENV 400
R+ +T+ E+Q+R+ K + +LCIG GQG+A+ +E +
Sbjct 358 RVLVTLLYEMQKRDAKKGLATLCIGGGQGVALAVERL 394
Lambda K H a alpha
0.317 0.135 0.382 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1719816
Database: cffdca0a3ef76ff236851b3c6135b9c7.SwissProt.fasta
Posted date: May 19, 2024 7:52 AM
Number of letters in database: 5,558
Number of sequences in database: 14
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
