BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: ede877e78f4edbc2ea955d547998a626.SwissProt.fasta
19 sequences; 5,210 total letters
Query= ACIAD1692
Length=262
Score E
Sequences producing significant alignments: (Bits) Value
P76082 2,3-dehydroadipyl-CoA hydratase [Escherichia coli (strain ... 215 3e-73
Q1ZXF1 Probable enoyl-CoA hydratase, mitochondrial [Dictyostelium... 214 1e-72
P34559 Probable enoyl-CoA hydratase, mitochondrial [Caenorhabditi... 211 4e-71
P14604 Enoyl-CoA hydratase, mitochondrial [Rattus norvegicus] 207 9e-70
Q58DM8 Enoyl-CoA hydratase, mitochondrial [Bos taurus] 207 1e-69
Q8BH95 Enoyl-CoA hydratase, mitochondrial [Mus musculus] 206 2e-69
P30084 Enoyl-CoA hydratase, mitochondrial [Homo sapiens] 206 2e-69
O07137 Probable enoyl-CoA hydratase echA8 [Mycobacterium leprae (... 205 3e-69
P9WNN9 Probable enoyl-CoA hydratase EchA8 [Mycobacterium tubercul... 205 4e-69
P9WNN8 Probable enoyl-CoA hydratase echA8 [Mycobacterium tubercul... 205 4e-69
P64017 Probable enoyl-CoA hydratase echA8 [Mycobacterium bovis (s... 205 4e-69
Q5R646 Enoyl-CoA hydratase, mitochondrial [Pongo abelii] 201 2e-67
Q52995 Probable enoyl-CoA hydratase [Rhizobium meliloti (strain 1... 199 7e-67
A4YI89 3-hydroxypropionyl-coenzyme A dehydratase [Metallosphaera ... 186 7e-62
P52046 Short-chain-enoyl-CoA hydratase [Clostridium acetobutylicu... 179 7e-59
O34893 Putative enoyl-CoA hydratase/isomerase YngF [Bacillus subt... 177 2e-58
Q0AVM1 Crotonyl-CoA hydratase [Syntrophomonas wolfei subsp. wolfe... 171 5e-56
F4JML5 Probable enoyl-CoA hydratase 2, mitochondrial [Arabidopsis... 155 4e-49
Q9JLZ3 Methylglutaconyl-CoA hydratase, mitochondrial [Mus musculus] 152 6e-48
>P76082 2,3-dehydroadipyl-CoA hydratase [Escherichia coli (strain
K12)]
Length=255
Score = 215 bits (548), Expect = 3e-73
Identities = 109/246 (44%), Positives = 160/246 (65%), Gaps = 0/246 (0%)
Query 16 EQIAIVKINRPASKNALNTEVRKQLAQAFTELSFNDQINAIVLTGGEDVFAAGADLKEMA 75
+++ ++ +NRPA++NALN + QL + + I+ V+TG FAAGADL EMA
Sbjct 10 QRVLLLTLNRPAARNALNNALLMQLVNELEAAATDTSISVCVITGNARFFAAGADLNEMA 69
Query 76 TASSTDMLLRHTERYWNAIAQCPKPVIAAVNGYALGGGCELAMHTDIIIAGKSATFGQPE 135
L + W + KP+IAAVNGYALG GCELA+ D+++AG++A FG PE
Sbjct 70 EKDLAATLNDTRPQLWARLQAFNKPLIAAVNGYALGAGCELALLCDVVVAGENARFGLPE 129
Query 136 IKVGLMPGAGGTQRLFRAVGKFHAMRMIMTGVMVPAEEAYLIGLVSQVTEDSQTIPTAIK 195
I +G+MPGAGGTQRL R+VGK A +M+++G + A++A GLVS V T+ A++
Sbjct 130 ITLGIMPGAGGTQRLIRSVGKSLASKMVLSGESITAQQAQQAGLVSDVFPSDLTLEYALQ 189
Query 196 MAQSLAKMPPIALQQIKEVALMSEDVPLNAGLTLERKSFQLLFSTEDKNEGINAFIEKRK 255
+A +A+ P+ALQ K+ S++V L AGL ER+ F LL +TED++EGI+AF++KR
Sbjct 190 LASKMARHSPLALQAAKQALRQSQEVALQAGLAQERQLFTLLAATEDRHEGISAFLQKRT 249
Query 256 PSYHGK 261
P + G+
Sbjct 250 PDFKGR 255
>Q1ZXF1 Probable enoyl-CoA hydratase, mitochondrial [Dictyostelium
discoideum]
Length=277
Score = 214 bits (546), Expect = 1e-72
Identities = 109/245 (44%), Positives = 152/245 (62%), Gaps = 0/245 (0%)
Query 17 QIAIVKINRPASKNALNTEVRKQLAQAFTELSFNDQINAIVLTGGEDVFAAGADLKEMAT 76
++ +V +NRP S NAL+ + ++ A + + +I++TG E FAAGAD+KEM
Sbjct 33 RVGLVTLNRPKSLNALSDGLISEINSAVKLFQEDKDVGSIIITGSEKAFAAGADIKEMEK 92
Query 77 ASSTDMLLRHTERYWNAIAQCPKPVIAAVNGYALGGGCELAMHTDIIIAGKSATFGQPEI 136
+ D W+ + + KP+IAAVNGYALGGGCELAM DIIIAG+ A FGQPEI
Sbjct 93 VTLPDAYNNDLLAQWHDLTKIRKPIIAAVNGYALGGGCELAMMCDIIIAGEKAVFGQPEI 152
Query 137 KVGLMPGAGGTQRLFRAVGKFHAMRMIMTGVMVPAEEAYLIGLVSQVTEDSQTIPTAIKM 196
K+G +PG GGTQRL RA+GK AM +++TG + A EA GLVS+V + + A KM
Sbjct 153 KLGTIPGCGGTQRLIRAIGKSKAMELVLTGNNLTAVEAEKAGLVSKVVPVEELLTEATKM 212
Query 197 AQSLAKMPPIALQQIKEVALMSEDVPLNAGLTLERKSFQLLFSTEDKNEGINAFIEKRKP 256
A+ +A + + KE S ++ L G+ ER+ F F T D+ EG+NAF+EKR P
Sbjct 213 AEKIASYSQLTVAMAKEAVNASYELTLQEGIRFERRMFHSTFGTHDQKEGMNAFVEKRTP 272
Query 257 SYHGK 261
++H K
Sbjct 273 TWHNK 277
>P34559 Probable enoyl-CoA hydratase, mitochondrial [Caenorhabditis
elegans]
Length=288
Score = 211 bits (537), Expect = 4e-71
Identities = 110/246 (45%), Positives = 151/246 (61%), Gaps = 0/246 (0%)
Query 16 EQIAIVKINRPASKNALNTEVRKQLAQAFTELSFNDQINAIVLTGGEDVFAAGADLKEMA 75
+ +A++K+NRP + NAL ++ +LA A L + + AIV+TG E FAAGAD+KEM
Sbjct 43 QNVALIKLNRPKALNALCAQLMTELADALEVLDTDKSVGAIVITGSERAFAAGADIKEMT 102
Query 76 TASSTDMLLRHTERYWNAIAQCPKPVIAAVNGYALGGGCELAMHTDIIIAGKSATFGQPE 135
W A++ KPVIAAVNG+ALGGG ELAM DII AG+ A FGQPE
Sbjct 103 NNEFATTFSGSFLSNWTAVSDVKKPVIAAVNGFALGGGNELAMMCDIIYAGEKARFGQPE 162
Query 136 IKVGLMPGAGGTQRLFRAVGKFHAMRMIMTGVMVPAEEAYLIGLVSQVTEDSQTIPTAIK 195
I +G +PGAGGTQR RA GK AM + +TG V A+EA G+VS++ Q + A+K
Sbjct 163 INIGTIPGAGGTQRWARAAGKSFAMEVCLTGNHVTAQEAKEHGIVSKIFPADQVVGEAVK 222
Query 196 MAQSLAKMPPIALQQIKEVALMSEDVPLNAGLTLERKSFQLLFSTEDKNEGINAFIEKRK 255
+ + +A P+ +Q KE + ++ L GL ER+ F F+T+D+ EG+ AF EKRK
Sbjct 223 LGEKIADQSPLIVQMAKEAVNKAYELTLQEGLHFERRLFHATFATKDRKEGMTAFAEKRK 282
Query 256 PSYHGK 261
P + K
Sbjct 283 PQWESK 288
>P14604 Enoyl-CoA hydratase, mitochondrial [Rattus norvegicus]
Length=290
Score = 207 bits (528), Expect = 9e-70
Identities = 111/241 (46%), Positives = 154/241 (64%), Gaps = 0/241 (0%)
Query 18 IAIVKINRPASKNALNTEVRKQLAQAFTELSFNDQINAIVLTGGEDVFAAGADLKEMATA 77
+ ++++NRP + NAL + ++L QA + + AIVLTGGE FAAGAD+KEM
Sbjct 47 VGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTGGEKAFAAGADIKEMQNR 106
Query 78 SSTDMLLRHTERYWNAIAQCPKPVIAAVNGYALGGGCELAMHTDIIIAGKSATFGQPEIK 137
+ D +W+ I + KPVIAAVNGYALGGGCELAM DII AG+ A FGQPEI
Sbjct 107 TFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQPEIL 166
Query 138 VGLMPGAGGTQRLFRAVGKFHAMRMIMTGVMVPAEEAYLIGLVSQVTEDSQTIPTAIKMA 197
+G +PGAGGTQRL RAVGK AM M++TG + A++A GLVS++ + AI+ A
Sbjct 167 LGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVEEAIQCA 226
Query 198 QSLAKMPPIALQQIKEVALMSEDVPLNAGLTLERKSFQLLFSTEDKNEGINAFIEKRKPS 257
+ +A I + KE + ++ L G LE+K F F+T+D+ EG++AF+EKRK +
Sbjct 227 EKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFATDDRREGMSAFVEKRKAN 286
Query 258 Y 258
+
Sbjct 287 F 287
>Q58DM8 Enoyl-CoA hydratase, mitochondrial [Bos taurus]
Length=290
Score = 207 bits (527), Expect = 1e-69
Identities = 111/241 (46%), Positives = 154/241 (64%), Gaps = 0/241 (0%)
Query 18 IAIVKINRPASKNALNTEVRKQLAQAFTELSFNDQINAIVLTGGEDVFAAGADLKEMATA 77
+ ++++NRP + NAL + +L QA + + AIVLTGGE VFAAGAD+KEM +
Sbjct 47 VGLIQLNRPKALNALCNGLIVELNQALQAFEEDPAVGAIVLTGGEKVFAAGADIKEMQSL 106
Query 78 SSTDMLLRHTERYWNAIAQCPKPVIAAVNGYALGGGCELAMHTDIIIAGKSATFGQPEIK 137
+ + +W+ + + KPVIAAVNGYALGGGCELAM DII AG+ A FGQPEI
Sbjct 107 TFQNCYSGGFLSHWDQLTRVKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQPEIL 166
Query 138 VGLMPGAGGTQRLFRAVGKFHAMRMIMTGVMVPAEEAYLIGLVSQVTEDSQTIPTAIKMA 197
+G +PGAGGTQRL RAVGK AM M++TG + A++A GLVS++ + AI+ A
Sbjct 167 IGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETVVEEAIQCA 226
Query 198 QSLAKMPPIALQQIKEVALMSEDVPLNAGLTLERKSFQLLFSTEDKNEGINAFIEKRKPS 257
+ +A I KE + ++ L G+ LE+K F F+TED+ EG+ AF+EKRK +
Sbjct 227 EKIASNSKIVTAMAKESVNAAFEMTLAEGVKLEKKLFYSTFATEDRKEGMAAFVEKRKAN 286
Query 258 Y 258
+
Sbjct 287 F 287
>Q8BH95 Enoyl-CoA hydratase, mitochondrial [Mus musculus]
Length=290
Score = 206 bits (525), Expect = 2e-69
Identities = 109/241 (45%), Positives = 154/241 (64%), Gaps = 0/241 (0%)
Query 18 IAIVKINRPASKNALNTEVRKQLAQAFTELSFNDQINAIVLTGGEDVFAAGADLKEMATA 77
+ ++++NRP + NAL + ++L QA + + AIVLTGG+ FAAGAD+KEM
Sbjct 47 VGLIQLNRPKALNALCNGLIEELNQALETFEQDPAVGAIVLTGGDKAFAAGADIKEMQNR 106
Query 78 SSTDMLLRHTERYWNAIAQCPKPVIAAVNGYALGGGCELAMHTDIIIAGKSATFGQPEIK 137
+ D +W+ I + KPVIAAVNGYALGGGCELAM DII AG+ A FGQPEI
Sbjct 107 TFQDCYSSKFLSHWDHITRVKKPVIAAVNGYALGGGCELAMMCDIIYAGEKAQFGQPEIL 166
Query 138 VGLMPGAGGTQRLFRAVGKFHAMRMIMTGVMVPAEEAYLIGLVSQVTEDSQTIPTAIKMA 197
+G +PGAGGTQRL RAVGK AM M++TG + A++A GLVS++ + + AI+ A
Sbjct 167 LGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVEKLVEEAIQCA 226
Query 198 QSLAKMPPIALQQIKEVALMSEDVPLNAGLTLERKSFQLLFSTEDKNEGINAFIEKRKPS 257
+ +A I + KE + ++ L G LE++ F F+T+D+ EG+ AF+EKRK +
Sbjct 227 EKIASNSKIVVAMAKESVNAAFEMTLTEGNKLEKRLFYSTFATDDRREGMTAFVEKRKAN 286
Query 258 Y 258
+
Sbjct 287 F 287
>P30084 Enoyl-CoA hydratase, mitochondrial [Homo sapiens]
Length=290
Score = 206 bits (525), Expect = 2e-69
Identities = 109/241 (45%), Positives = 151/241 (63%), Gaps = 0/241 (0%)
Query 18 IAIVKINRPASKNALNTEVRKQLAQAFTELSFNDQINAIVLTGGEDVFAAGADLKEMATA 77
+ ++++NRP + NAL + +L QA + + AIVLTGG+ FAAGAD+KEM
Sbjct 47 VGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNL 106
Query 78 SSTDMLLRHTERYWNAIAQCPKPVIAAVNGYALGGGCELAMHTDIIIAGKSATFGQPEIK 137
S D ++W+ + Q KPVIAAVNGYA GGGCELAM DII AG+ A F QPEI
Sbjct 107 SFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEIL 166
Query 138 VGLMPGAGGTQRLFRAVGKFHAMRMIMTGVMVPAEEAYLIGLVSQVTEDSQTIPTAIKMA 197
+G +PGAGGTQRL RAVGK AM M++TG + A++A GLVS++ + AI+ A
Sbjct 167 IGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCA 226
Query 198 QSLAKMPPIALQQIKEVALMSEDVPLNAGLTLERKSFQLLFSTEDKNEGINAFIEKRKPS 257
+ +A I + KE + ++ L G LE+K F F+T+D+ EG+ AF+EKRK +
Sbjct 227 EKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKAN 286
Query 258 Y 258
+
Sbjct 287 F 287
>O07137 Probable enoyl-CoA hydratase echA8 [Mycobacterium leprae
(strain TN)]
Length=257
Score = 205 bits (522), Expect = 3e-69
Identities = 109/243 (45%), Positives = 155/243 (64%), Gaps = 0/243 (0%)
Query 16 EQIAIVKINRPASKNALNTEVRKQLAQAFTELSFNDQINAIVLTGGEDVFAAGADLKEMA 75
+++ I+ +NRP + NALN+++ ++ A EL + + AI++TG VFAAGAD+KEMA
Sbjct 12 QRVGIITLNRPQALNALNSQMMNEITNAAKELDIDPDVGAILITGSPKVFAAGADIKEMA 71
Query 76 TASSTDMLLRHTERYWNAIAQCPKPVIAAVNGYALGGGCELAMHTDIIIAGKSATFGQPE 135
+ + TD W +A P+IAAV GYALGGGCELAM D++IA +A FGQPE
Sbjct 72 SLTFTDAFDADFFSAWGKLAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPE 131
Query 136 IKVGLMPGAGGTQRLFRAVGKFHAMRMIMTGVMVPAEEAYLIGLVSQVTEDSQTIPTAIK 195
IK+G++PG GG+QRL RA+GK AM +I+TG + A EA GLVS+V +P A
Sbjct 132 IKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADDLLPEAKA 191
Query 196 MAQSLAKMPPIALQQIKEVALMSEDVPLNAGLTLERKSFQLLFSTEDKNEGINAFIEKRK 255
+A ++++M A + KE S + L GL ER+ F F T+D++EG+ AFIEKR
Sbjct 192 VATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHSTFVTDDQSEGMAAFIEKRA 251
Query 256 PSY 258
P +
Sbjct 252 PQF 254
>P9WNN9 Probable enoyl-CoA hydratase EchA8 [Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv)]
Length=257
Score = 205 bits (521), Expect = 4e-69
Identities = 109/243 (45%), Positives = 152/243 (63%), Gaps = 0/243 (0%)
Query 16 EQIAIVKINRPASKNALNTEVRKQLAQAFTELSFNDQINAIVLTGGEDVFAAGADLKEMA 75
+++ I+ +NRP + NALN++V ++ A TEL + I AI++TG FAAGAD+KEMA
Sbjct 12 QRVGIITLNRPQALNALNSQVMNEVTSAATELDDDPDIGAIIITGSAKAFAAGADIKEMA 71
Query 76 TASSTDMLLRHTERYWNAIAQCPKPVIAAVNGYALGGGCELAMHTDIIIAGKSATFGQPE 135
+ D W +A P IAAV GYALGGGCELAM D++IA +A FGQPE
Sbjct 72 DLTFADAFTADFFATWGKLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPE 131
Query 136 IKVGLMPGAGGTQRLFRAVGKFHAMRMIMTGVMVPAEEAYLIGLVSQVTEDSQTIPTAIK 195
IK+G++PG GG+QRL RA+GK AM +I+TG + A EA GLVS+V + A
Sbjct 132 IKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPADDLLTEARA 191
Query 196 MAQSLAKMPPIALQQIKEVALMSEDVPLNAGLTLERKSFQLLFSTEDKNEGINAFIEKRK 255
A ++++M A + KE + + L+ GL ER+ F F+TED++EG+ AFIEKR
Sbjct 192 TATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAFATEDQSEGMAAFIEKRA 251
Query 256 PSY 258
P +
Sbjct 252 PQF 254
>P9WNN8 Probable enoyl-CoA hydratase echA8 [Mycobacterium tuberculosis
(strain CDC 1551 / Oshkosh)]
Length=257
Score = 205 bits (521), Expect = 4e-69
Identities = 109/243 (45%), Positives = 152/243 (63%), Gaps = 0/243 (0%)
Query 16 EQIAIVKINRPASKNALNTEVRKQLAQAFTELSFNDQINAIVLTGGEDVFAAGADLKEMA 75
+++ I+ +NRP + NALN++V ++ A TEL + I AI++TG FAAGAD+KEMA
Sbjct 12 QRVGIITLNRPQALNALNSQVMNEVTSAATELDDDPDIGAIIITGSAKAFAAGADIKEMA 71
Query 76 TASSTDMLLRHTERYWNAIAQCPKPVIAAVNGYALGGGCELAMHTDIIIAGKSATFGQPE 135
+ D W +A P IAAV GYALGGGCELAM D++IA +A FGQPE
Sbjct 72 DLTFADAFTADFFATWGKLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPE 131
Query 136 IKVGLMPGAGGTQRLFRAVGKFHAMRMIMTGVMVPAEEAYLIGLVSQVTEDSQTIPTAIK 195
IK+G++PG GG+QRL RA+GK AM +I+TG + A EA GLVS+V + A
Sbjct 132 IKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPADDLLTEARA 191
Query 196 MAQSLAKMPPIALQQIKEVALMSEDVPLNAGLTLERKSFQLLFSTEDKNEGINAFIEKRK 255
A ++++M A + KE + + L+ GL ER+ F F+TED++EG+ AFIEKR
Sbjct 192 TATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAFATEDQSEGMAAFIEKRA 251
Query 256 PSY 258
P +
Sbjct 252 PQF 254
>P64017 Probable enoyl-CoA hydratase echA8 [Mycobacterium bovis
(strain ATCC BAA-935 / AF2122/97)]
Length=257
Score = 205 bits (521), Expect = 4e-69
Identities = 109/243 (45%), Positives = 152/243 (63%), Gaps = 0/243 (0%)
Query 16 EQIAIVKINRPASKNALNTEVRKQLAQAFTELSFNDQINAIVLTGGEDVFAAGADLKEMA 75
+++ I+ +NRP + NALN++V ++ A TEL + I AI++TG FAAGAD+KEMA
Sbjct 12 QRVGIITLNRPQALNALNSQVMNEVTSAATELDDDPDIGAIIITGSAKAFAAGADIKEMA 71
Query 76 TASSTDMLLRHTERYWNAIAQCPKPVIAAVNGYALGGGCELAMHTDIIIAGKSATFGQPE 135
+ D W +A P IAAV GYALGGGCELAM D++IA +A FGQPE
Sbjct 72 DLTFADAFTADFFATWGKLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPE 131
Query 136 IKVGLMPGAGGTQRLFRAVGKFHAMRMIMTGVMVPAEEAYLIGLVSQVTEDSQTIPTAIK 195
IK+G++PG GG+QRL RA+GK AM +I+TG + A EA GLVS+V + A
Sbjct 132 IKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPADDLLTEARA 191
Query 196 MAQSLAKMPPIALQQIKEVALMSEDVPLNAGLTLERKSFQLLFSTEDKNEGINAFIEKRK 255
A ++++M A + KE + + L+ GL ER+ F F+TED++EG+ AFIEKR
Sbjct 192 TATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAFATEDQSEGMAAFIEKRA 251
Query 256 PSY 258
P +
Sbjct 252 PQF 254
>Q5R646 Enoyl-CoA hydratase, mitochondrial [Pongo abelii]
Length=290
Score = 201 bits (512), Expect = 2e-67
Identities = 108/241 (45%), Positives = 148/241 (61%), Gaps = 0/241 (0%)
Query 18 IAIVKINRPASKNALNTEVRKQLAQAFTELSFNDQINAIVLTGGEDVFAAGADLKEMATA 77
+ ++++NRP + NAL + +L QA + + AIVLTGG+ FAAGAD+KEM
Sbjct 47 VGLIQLNRPKALNALCDGLIDELNQALKIFEEDPAVGAIVLTGGDKAFAAGADIKEMQNL 106
Query 78 SSTDMLLRHTERYWNAIAQCPKPVIAAVNGYALGGGCELAMHTDIIIAGKSATFGQPEIK 137
S D ++W+ + Q KPVIAAVNGYA GGGCELAM DII AG+ A F QPEI
Sbjct 107 SFQDCYSSKFLKHWDHLTQIKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEIL 166
Query 138 VGLMPGAGGTQRLFRAVGKFHAMRMIMTGVMVPAEEAYLIGLVSQVTEDSQTIPTAIKMA 197
+G +PGAGGTQRL R VGK AM M++TG + A++A GLVS++ + AI+ A
Sbjct 167 IGTIPGAGGTQRLTRTVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCA 226
Query 198 QSLAKMPPIALQQIKEVALMSEDVPLNAGLTLERKSFQLLFSTEDKNEGINAFIEKRKPS 257
+ +A I KE + ++ L G LE+K F F+T D+ EG+ AF+EKRK +
Sbjct 227 EKIASNSKIIAAMAKESVNAAFEMTLAEGSKLEKKLFYSTFATNDRKEGMTAFVEKRKAN 286
Query 258 Y 258
+
Sbjct 287 F 287
>Q52995 Probable enoyl-CoA hydratase [Rhizobium meliloti (strain
1021)]
Length=257
Score = 199 bits (506), Expect = 7e-67
Identities = 109/242 (45%), Positives = 148/242 (61%), Gaps = 0/242 (0%)
Query 17 QIAIVKINRPASKNALNTEVRKQLAQAFTELSFNDQINAIVLTGGEDVFAAGADLKEMAT 76
++ ++ +NRP + NALN + ++L A + + AIVL G E FAAGAD+KEM
Sbjct 13 RVGLITLNRPQALNALNAVLMRELDAALKAFDADRAVGAIVLAGSEKAFAAGADIKEMQG 72
Query 77 ASSTDMLLRHTERYWNAIAQCPKPVIAAVNGYALGGGCELAMHTDIIIAGKSATFGQPEI 136
D L W +A KP+IAAV+G+ALGGGCELAM D IIA ++A FGQPEI
Sbjct 73 LDFVDGYLADFLGGWEHVANARKPMIAAVSGFALGGGCELAMMCDFIIASETAKFGQPEI 132
Query 137 KVGLMPGAGGTQRLFRAVGKFHAMRMIMTGVMVPAEEAYLIGLVSQVTEDSQTIPTAIKM 196
+G++PG GG+QRL RAVGK AM +I+TG M+ A EA GLVS+V + + A+
Sbjct 133 TLGVIPGMGGSQRLTRAVGKAKAMDLILTGRMMDAAEAERSGLVSRVVAPDRLLEEALGA 192
Query 197 AQSLAKMPPIALQQIKEVALMSEDVPLNAGLTLERKSFQLLFSTEDKNEGINAFIEKRKP 256
A+ +A A KE S ++ L GL ER+ FQ LF+TED+ EG+ AF+ KRK
Sbjct 193 AEKIASFSLPAAMMAKEAVNRSLELTLAEGLRFERRLFQSLFATEDQKEGMAAFVAKRKA 252
Query 257 SY 258
+
Sbjct 253 EF 254
>A4YI89 3-hydroxypropionyl-coenzyme A dehydratase [Metallosphaera
sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509
/ TH2)]
Length=259
Score = 186 bits (473), Expect = 7e-62
Identities = 101/243 (42%), Positives = 147/243 (60%), Gaps = 2/243 (1%)
Query 21 VKINRPASKNALNTEVRKQLAQAFTELSFNDQINAIVLTGGEDVFAAGADLKEM--ATAS 78
+ +NRP NALN ++ ++L +A ++ + +I I++TG F AGAD+ + T +
Sbjct 17 ITLNRPDKLNALNAKLLEELDRAVSQAESDPEIRVIIITGKGKAFCAGADITQFNQLTPA 76
Query 79 STDMLLRHTERYWNAIAQCPKPVIAAVNGYALGGGCELAMHTDIIIAGKSATFGQPEIKV 138
+ + I KP IA +NGYALGGG ELA+ DI IA + A G PEI +
Sbjct 77 EAWKFSKKGREIMDKIEALSKPTIAMINGYALGGGLELALACDIRIAAEEAQLGLPEINL 136
Query 139 GLMPGAGGTQRLFRAVGKFHAMRMIMTGVMVPAEEAYLIGLVSQVTEDSQTIPTAIKMAQ 198
G+ PG GGTQRL R +GK A+ M+MTG +P ++A GLV++V + K+A+
Sbjct 137 GIYPGYGGTQRLTRVIGKGRALEMMMTGDRIPGKDAEKYGLVNRVVPLANLEQETRKLAE 196
Query 199 SLAKMPPIALQQIKEVALMSEDVPLNAGLTLERKSFQLLFSTEDKNEGINAFIEKRKPSY 258
+AK PI+L IKEV D PL +GL LE + ++FSTEDK EG++AF+EKR+P++
Sbjct 197 KIAKKSPISLALIKEVVNRGLDSPLLSGLALESVGWGVVFSTEDKKEGVSAFLEKREPTF 256
Query 259 HGK 261
GK
Sbjct 257 KGK 259
>P52046 Short-chain-enoyl-CoA hydratase [Clostridium acetobutylicum
(strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM
B-1787)]
Length=261
Score = 179 bits (453), Expect = 7e-59
Identities = 99/242 (41%), Positives = 148/242 (61%), Gaps = 3/242 (1%)
Query 17 QIAIVKINRPASKNALNTEVRKQLAQAFTELSFNDQINAIVLTG-GEDVFAAGADLKEMA 75
++A+V INRP + NALN++ K++ E+ + ++ A++LTG GE F AGAD+ EM
Sbjct 13 KVAVVTINRPKALNALNSDTLKEMDYVIGEIENDSEVLAVILTGAGEKSFVAGADISEMK 72
Query 76 TASSTDMLLRHT--ERYWNAIAQCPKPVIAAVNGYALGGGCELAMHTDIIIAGKSATFGQ 133
++ + + + + KPVIAAVNG+ALGGGCE+AM DI IA +A FGQ
Sbjct 73 EMNTIEGRKFGILGNKVFRRLELLEKPVIAAVNGFALGGGCEIAMSCDIRIASSNARFGQ 132
Query 134 PEIKVGLMPGAGGTQRLFRAVGKFHAMRMIMTGVMVPAEEAYLIGLVSQVTEDSQTIPTA 193
PE+ +G+ PG GGTQRL R VG A ++I T + A+EA IGLV++V E S+ + TA
Sbjct 133 PEVGLGITPGFGGTQRLSRLVGMGMAKQLIFTAQNIKADEALRIGLVNKVVEPSELMNTA 192
Query 194 IKMAQSLAKMPPIALQQIKEVALMSEDVPLNAGLTLERKSFQLLFSTEDKNEGINAFIEK 253
++A + P+A++ K+ ++ L E ++F FSTED+ + + AFIEK
Sbjct 193 KEIANKIVSNAPVAVKLSKQAINRGMQCDIDTALAFESEAFGECFSTEDQKDAMTAFIEK 252
Query 254 RK 255
RK
Sbjct 253 RK 254
>O34893 Putative enoyl-CoA hydratase/isomerase YngF [Bacillus
subtilis (strain 168)]
Length=260
Score = 177 bits (450), Expect = 2e-58
Identities = 102/251 (41%), Positives = 147/251 (59%), Gaps = 9/251 (4%)
Query 16 EQIAIVKINRPASKNALNTEVRKQLAQAFTELSFNDQINAIVLTG-GEDVFAAGADLKEM 74
E +A++ +NRP + NAL+ E+ + L E+ FN I ++LTG GE F AGADLKE
Sbjct 12 EHMALITLNRPQAANALSAEMLRNLQMIIQEIEFNSNIRCVILTGTGEKAFCAGADLKER 71
Query 75 ATASSTDML-----LRHTERYWNAIAQCPKPVIAAVNGYALGGGCELAMHTDIIIAGKSA 129
+L ++ T +A+ P+PVIAA+NG ALGGG ELA+ D+ IA ++A
Sbjct 72 IKLKEDQVLESVSLIQRTAALLDAL---PQPVIAAINGSALGGGLELALACDLRIATEAA 128
Query 130 TFGQPEIKVGLMPGAGGTQRLFRAVGKFHAMRMIMTGVMVPAEEAYLIGLVSQVTEDSQT 189
G PE + ++PGAGGTQRL R +G+ A I TG V A EA IGLV VT
Sbjct 129 VLGLPETGLAIIPGAGGTQRLPRLIGRGKAKEFIYTGRRVTAHEAKEIGLVEHVTAPCDL 188
Query 190 IPTAIKMAQSLAKMPPIALQQIKEVALMSEDVPLNAGLTLERKSFQLLFSTEDKNEGINA 249
+P A ++A +++ PIA++Q K + L GL +E+K+++ T+D+ EG+ A
Sbjct 189 MPKAEELAAAISANGPIAVRQAKFAINKGLETDLATGLAIEQKAYEQTIPTKDRREGLQA 248
Query 250 FIEKRKPSYHG 260
F EKR+ Y G
Sbjct 249 FQEKRRAVYKG 259
>Q0AVM1 Crotonyl-CoA hydratase [Syntrophomonas wolfei subsp. wolfei
(strain DSM 2245B / Goettingen)]
Length=260
Score = 171 bits (434), Expect = 5e-56
Identities = 94/249 (38%), Positives = 151/249 (61%), Gaps = 3/249 (1%)
Query 16 EQIAIVKINRPASKNALNTEVRKQLAQAFTELSFNDQINAIVLTG-GEDVFAAGADLKEM 74
E++A++ INRP + NALN + ++ A T ++ + + +++TG G+ F AGAD+ M
Sbjct 12 EKLAVLYINRPKAMNALNKDTLLEIKDAVTAVNDDPAVELLIITGSGDKSFVAGADIAFM 71
Query 75 ATASSTDMLLRHT--ERYWNAIAQCPKPVIAAVNGYALGGGCELAMHTDIIIAGKSATFG 132
S+ + ++ + I KPVIAAVNG+ALGGGCELAM D IA +A FG
Sbjct 72 QNLSAMEAREFGALGQKVFRLIEAMEKPVIAAVNGFALGGGCELAMCCDFRIAASNAKFG 131
Query 133 QPEIKVGLMPGAGGTQRLFRAVGKFHAMRMIMTGVMVPAEEAYLIGLVSQVTEDSQTIPT 192
QPE+ +G+ PG GGTQRL R VG A +++ T ++ A+EA+ IGLV++V + + +P
Sbjct 132 QPEVGLGITPGFGGTQRLPRLVGPGMAKQLLYTADVINADEAFRIGLVNKVVQPEELLPE 191
Query 193 AIKMAQSLAKMPPIALQQIKEVALMSEDVPLNAGLTLERKSFQLLFSTEDKNEGINAFIE 252
K+A + +A++ K A ++ +++E +F L F+T+D+ EG+ AF+E
Sbjct 192 VKKIAGRILSKGQLAVRLSKAAANEGMQTDIDRAMSIEADAFGLCFATQDQKEGMTAFLE 251
Query 253 KRKPSYHGK 261
KRK ++ K
Sbjct 252 KRKANFISK 260
>F4JML5 Probable enoyl-CoA hydratase 2, mitochondrial [Arabidopsis
thaliana]
Length=301
Score = 155 bits (391), Expect = 4e-49
Identities = 95/246 (39%), Positives = 142/246 (58%), Gaps = 9/246 (4%)
Query 21 VKINRPASKNALNTEVRKQLAQAFTELSFNDQINAIVLTG-GEDVFAAGADLKEMATASS 79
V ++RP +KNA+N E+ K L AF + ++ +++ VF AGADLKE T S
Sbjct 58 VNLDRPVTKNAINKEMLKSLQNAFESIHQDNSARVVMIRSLVPGVFCAGADLKERRTMSP 117
Query 80 TDMLLRHTE----RY-WNAIAQCPKPVIAAVNGYALGGGCELAMHTDIIIAGKSATFGQP 134
+++ HT RY ++ I P IAA+ G ALGGG E+A+ D+ I G++A FG P
Sbjct 118 SEV---HTYVNSLRYMFSFIEALSIPTIAAIEGAALGGGLEMALACDLRICGENAVFGLP 174
Query 135 EIKVGLMPGAGGTQRLFRAVGKFHAMRMIMTGVMVPAEEAYLIGLVSQVTEDSQTIPTAI 194
E + ++PGAGGTQRL R VG+ + +I TG + A EA GLV+ + AI
Sbjct 175 ETGLAIIPGAGGTQRLSRLVGRSVSKELIFTGRKIDAIEAANKGLVNICVTAGEAHEKAI 234
Query 195 KMAQSLAKMPPIALQQIKEVALMSEDVPLNAGLTLERKSFQLLFSTEDKNEGINAFIEKR 254
+MAQ + + P+A++ K+ + + +GL +E +Q L +T+D+ EG+ AF EKR
Sbjct 235 EMAQQINEKGPLAIKMAKKAIDEGIETNMASGLEVEEMCYQKLLNTQDRLEGLAAFAEKR 294
Query 255 KPSYHG 260
KP Y G
Sbjct 295 KPLYTG 300
>Q9JLZ3 Methylglutaconyl-CoA hydratase, mitochondrial [Mus musculus]
Length=314
Score = 152 bits (384), Expect = 6e-48
Identities = 94/251 (37%), Positives = 138/251 (55%), Gaps = 7/251 (3%)
Query 18 IAIVKINRPASKNALNTEVRKQLAQAFTELSFNDQINAIVLTGG-EDVFAAGADLKEMAT 76
I ++ INR KNAL+ + K L++A L + ++ I++ +F AGADLKE A
Sbjct 64 IVVLGINRAYGKNALSKNLLKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAK 123
Query 77 ASSTDM--LLRHTERYWNAIAQCPKPVIAAVNGYALGGGCELAMHTDIIIAGKSATFGQP 134
S+++ + N IA P P IAA++G ALGGG ELA+ DI +A SA G
Sbjct 124 MHSSEVGPFVSKIRSVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLV 183
Query 135 EIKVGLMPGAGGTQRLFRAVGKFHAMRMIMTGVMVPAEEAYLIGLVSQVTEDSQTIPTAI 194
E K+ ++PG GGTQRL RA+G A +I + ++ +EA +GL+S V E +Q A
Sbjct 184 ETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGQEAKAVGLISHVLEQNQEGDAAY 243
Query 195 KMAQSLAK----MPPIALQQIKEVALMSEDVPLNAGLTLERKSFQLLFSTEDKNEGINAF 250
+ A LA+ P+A++ K +V L GL +E + ST+D+ EG+ AF
Sbjct 244 RKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAF 303
Query 251 IEKRKPSYHGK 261
EKR P Y G+
Sbjct 304 KEKRPPRYKGE 314
Lambda K H a alpha
0.320 0.134 0.380 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 945035
Database: ede877e78f4edbc2ea955d547998a626.SwissProt.fasta
Posted date: May 19, 2024 2:15 AM
Number of letters in database: 5,210
Number of sequences in database: 19
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
