BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 5450b98910b25653128b33cb82b8aae7.SwissProt.fasta
15 sequences; 5,904 total letters
Query= ACIAD1693
Length=385
Score E
Sequences producing significant alignments: (Bits) Value
J7TF92 3-(aryl)acrylate reductase [Clostridium sporogenes (strain... 295 6e-101
H6LGM6 Caffeyl-CoA reductase-Etf complex subunit CarC [Acetobacte... 292 7e-100
O34421 Probable acyl-CoA dehydrogenase YngJ [Bacillus subtilis (s... 291 3e-99
P45857 Acyl-CoA dehydrogenase [Bacillus subtilis (strain 168)] 290 8e-99
G3KIM8 Acryloyl-CoA reductase (NADH) [Anaerotignum propionicum] 285 6e-97
P9WQG1 Probable acyl-CoA dehydrogenase FadE25 [Mycobacterium tube... 281 2e-95
P9WQG0 Probable acyl-CoA dehydrogenase fadE25 [Mycobacterium tube... 281 2e-95
P63428 Probable acyl-CoA dehydrogenase fadE25 [Mycobacterium bovi... 281 2e-95
Q5RAS0 Short-chain specific acyl-CoA dehydrogenase, mitochondrial... 274 2e-92
P46703 Probable acyl-CoA dehydrogenase fadE25 [Mycobacterium lepr... 273 5e-92
P16219 Short-chain specific acyl-CoA dehydrogenase, mitochondrial... 272 2e-91
P52042 Acyl-CoA dehydrogenase, short-chain specific [Clostridium ... 263 1e-88
P15651 Short-chain specific acyl-CoA dehydrogenase, mitochondrial... 261 2e-87
Q3ZBF6 Short-chain specific acyl-CoA dehydrogenase, mitochondrial... 261 2e-87
Q07417 Short-chain specific acyl-CoA dehydrogenase, mitochondrial... 261 3e-87
>J7TF92 3-(aryl)acrylate reductase [Clostridium sporogenes (strain
ATCC 15579)]
Length=377
Score = 295 bits (755), Expect = 6e-101
Identities = 155/365 (42%), Positives = 233/365 (64%), Gaps = 2/365 (1%)
Query 16 RDFVKNELIPREHEVAEKDCIPEDIIQQMRELGLFGLTIPEEYGGLGITMEEEVNVAFEL 75
RDF + E+ P EV + P++I+++M + G FG+ +P+EYGG G V + E+
Sbjct 15 RDFAEQEIEPIADEVDKTAEFPKEIVKKMAQNGFFGIKMPKEYGGAGADNRAYVTIMEEI 74
Query 76 GQTSPAFRSLIGTNNGIGSSGLIIDGTEEQKQKYLPRYASGEIIGSFCLTEPEAGSDAAS 135
+ S + + N + + ++ GT+EQK+KYL GE +F LTEP AGSDA +
Sbjct 75 SRASGVAGIYLSSPNSLLGTPFLLVGTDEQKEKYLKPMIRGEKTLAFALTEPGAGSDAGA 134
Query 136 LKTTAVKDGDFYILNGTKRFITNAPHAATFTVMARTNPAIKGAGGISAFLVEANTPGITL 195
+ TTA ++GD+YILNG K FIT AP + V A+T+ + KG GI+ F+V++ G++
Sbjct 135 VATTAREEGDYYILNGRKTFITGAPISDNIIVFAKTDMS-KGTKGITTFIVDSKQEGVSF 193
Query 196 GKIDQKMGQKGSHTCDVIFENCRVPASALIGGVEGVGFKTAMKVLDKGRLHIGAYSVGVA 255
GK + KMG G T D+I EN +V S ++G + GF TAMK L GR+ + A ++G+A
Sbjct 194 GKPEDKMGMIGCPTSDIILENVKVHKSDILGELNK-GFITAMKTLSVGRIGVAAQALGIA 252
Query 256 ERMLNDALHYAVERKQFGQPIANFQLIQAMLADSKAEIYAAKCMVLDAARRRDEGQNIST 315
+ +++A+ YA +RKQF +PIA FQ IQ LA+ + ++ AAK +V +AA + D G+
Sbjct 253 QAAVDEAVKYAKQRKQFNRPIAKFQAIQFKLANMETKLNAAKLLVYNAAYKMDCGEKADK 312
Query 316 EASCAKMFATEMCGRVADRCVQIHGGAGYISEYSIERFYRDVRLFRLYEGTTQVQQIIIA 375
EAS AK FA E ++ + +QIHGG GYI +Y IER YRDVR+ +YEGT++VQQ++IA
Sbjct 313 EASMAKYFAAESAIQIVNDALQIHGGYGYIKDYKIERLYRDVRVIAIYEGTSEVQQMVIA 372
Query 376 KNMIK 380
N++K
Sbjct 373 SNLLK 377
>H6LGM6 Caffeyl-CoA reductase-Etf complex subunit CarC [Acetobacterium
woodii (strain ATCC 29683 / DSM 1030 / JCM 2381 / KCTC
1655 / WB1)]
Length=379
Score = 292 bits (748), Expect = 7e-100
Identities = 160/367 (44%), Positives = 227/367 (62%), Gaps = 3/367 (1%)
Query 16 RDFVKNELIPRE-HEVAEKDCIPEDIIQQMRELGLFGLTIPEEYGGLGITMEEEVNVAFE 74
RDF + EL EV E P++I+ +M + G FG+ IP+ GG G V E
Sbjct 15 RDFAEKELTTEILDEVEESGEFPQEILDKMAKFGFFGIKIPKSLGGSGGDHMSYVICMEE 74
Query 75 LGQTSPAFRSLIGTNNGIGSSGLIIDGTEEQKQKYLPRYASGEIIGSFCLTEPEAGSDAA 134
+ S + + N + L++ GTEEQ +KYL +G+ +F LTEP AGSDA
Sbjct 75 FARVSGVASVYLSSPNSLAGGPLLLSGTEEQIEKYLKPIITGKKKLAFALTEPGAGSDAG 134
Query 135 SLKTTAVKDGDFYILNGTKRFITNAPHAATFTVMARTNPAIKGAGGISAFLVEANTPGIT 194
+ TTAV GD+Y+LNG K FIT AP + A+T+ + KG GISAF+V+ + G++
Sbjct 135 GMSTTAVDMGDYYLLNGRKTFITMAPLCDDAVIYAKTDMS-KGTRGISAFIVDLKSEGVS 193
Query 195 LGKIDQKMGQKGSHTCDVIFENCRVPASALIGGVEGVGFKTAMKVLDKGRLHIGAYSVGV 254
+GK + KMG G T D+I E+ +VP +G V GF AMK LD GRL + + S+GV
Sbjct 194 MGKNEHKMGLIGCATSDIIMEDVKVPKENRLGEVNK-GFSNAMKTLDVGRLGVASQSIGV 252
Query 255 AERMLNDALHYAVERKQFGQPIANFQLIQAMLADSKAEIYAAKCMVLDAARRRDEGQNIS 314
A+ L++A+ YA ERKQFG+ IA+FQ I M+AD ++ AAK +V +AA D +N +
Sbjct 253 AQGALDEAIKYAKERKQFGKRIADFQAIAFMIADMATKLEAAKLLVYNAASLMDNKKNAT 312
Query 315 TEASCAKMFATEMCGRVADRCVQIHGGAGYISEYSIERFYRDVRLFRLYEGTTQVQQIII 374
EAS AK +A+E+C + + VQIHGG GYI EY +ER YRD R+F +YEGT+QVQQ++I
Sbjct 313 KEASMAKFYASEICNEICAKAVQIHGGYGYIKEYKVERMYRDCRVFTIYEGTSQVQQMVI 372
Query 375 AKNMIKE 381
+ ++K+
Sbjct 373 SGMLLKK 379
>O34421 Probable acyl-CoA dehydrogenase YngJ [Bacillus subtilis
(strain 168)]
Length=380
Score = 291 bits (744), Expect = 3e-99
Identities = 159/372 (43%), Positives = 226/372 (61%), Gaps = 1/372 (0%)
Query 9 QQLLSTIRDFVKNELIPREHEVAEKDCIPEDIIQQMRELGLFGLTIPEEYGGLGITMEEE 68
Q + ++DF K E+ P V + P ++M ELGL G+ PEEYGG G
Sbjct 10 QMVREMVKDFAKKEIAPHAEHVDQTGEFPMQTFKKMGELGLMGIPFPEEYGGSGGDTISY 69
Query 69 VNVAFELGQTSPAFRSLIGTNNGIGSSGLIIDGTEEQKQKYLPRYASGEIIGSFCLTEPE 128
E+G+ + +G+S L GTEEQKQ +L ASG +GSF LTEP
Sbjct 70 ALAVEEVGKACGSTGLSYAAAVSLGASPLYYFGTEEQKQTHLTPLASGTALGSFGLTEPN 129
Query 129 AGSDAASLKTTAVKDGDFYILNGTKRFITNAPHAATFTVMARTNPAIKGAGGISAFLVEA 188
AGSDA +T A+ +GD Y++NG K +ITNA +A T V A T G ISA +V
Sbjct 130 AGSDAGGTQTKAISNGDEYVINGEKCWITNASYARTVIVTAVTGKNKDGKNIISALIVPT 189
Query 189 NTPGITLGKIDQKMGQKGSHTCDVIFENCRVPASALIGGVEGVGFKTAMKVLDKGRLHIG 248
+TPG+T+ KMG +GS+T +++ E+ RVPA+ L+G GFK + LD GR+ I
Sbjct 190 DTPGLTITSPYDKMGVRGSNTAEILLEDVRVPAANLLGDPTK-GFKQFLYTLDGGRISIA 248
Query 249 AYSVGVAERMLNDALHYAVERKQFGQPIANFQLIQAMLADSKAEIYAAKCMVLDAARRRD 308
A +VG+A+ L+ +L YA ERKQFGQPI++FQ IQ LAD EI A+ MVL AA +D
Sbjct 249 ALAVGIAQAALDASLAYAKERKQFGQPISSFQAIQFKLADMAMEIDLARQMVLKAAWLKD 308
Query 309 EGQNISTEASCAKMFATEMCGRVADRCVQIHGGAGYISEYSIERFYRDVRLFRLYEGTTQ 368
+ + EA+ AK+FA+EM R ++ +QIHGG+GY+ EY +ER RD +L + EGT++
Sbjct 309 HNRPFTKEAAYAKLFASEMATRACNQAIQIHGGSGYMKEYGVERMLRDAKLMEIGEGTSE 368
Query 369 VQQIIIAKNMIK 380
+Q+++IA+ ++K
Sbjct 369 IQRLVIARQLLK 380
>P45857 Acyl-CoA dehydrogenase [Bacillus subtilis (strain 168)]
Length=379
Score = 290 bits (741), Expect = 8e-99
Identities = 154/365 (42%), Positives = 229/365 (63%), Gaps = 2/365 (1%)
Query 15 IRDFVKNELIPREHEVAEKDCIPEDIIQQMRELGLFGLTIPEEYGGLGITMEEEVNVAFE 74
+RDF + E+ P + + D P +I++M + GL G+ +PE+YGG G + + E
Sbjct 14 VRDFARKEIAPAAEIMEKTDEFPFQLIKKMGKHGLMGIPVPEQYGGAGADVVSYILAIHE 73
Query 75 LGQTSPAFRSLIGTNNGIGSSGLIIDGTEEQKQKYLPRYASGEIIGSFCLTEPEAGSDAA 134
+ + S A ++ + +G++ ++ G EEQK KY+P ASG+ +G+F LTEP +GSDA
Sbjct 74 ISRISAAVGVILSVHTSVGTNPILYFGNEEQKMKYIPNLASGDHLGAFALTEPHSGSDAG 133
Query 135 SLKTTAVKDGDFYILNGTKRFITNAPHAATFTVMARTNPAIKGAGGISAFLVEANTPGIT 194
SL+TTA+K Y+LNG+K FITN A + A T P +G GISAF+VE NTPG T
Sbjct 134 SLRTTAIKKNGKYLLNGSKIFITNGGAADIYITFALTAPD-QGRHGISAFIVEKNTPGFT 192
Query 195 LGKIDQKMGQKGSHTCDVIFENCRVPASALIGGVEGVGFKTAMKVLDKGRLHIGAYSVGV 254
+GK ++K+G GS+T ++IF+N VP + L+ G EG GF AM L+ GR+ I A ++G+
Sbjct 193 VGKKERKLGLYGSNTTELIFDNAEVPEANLL-GKEGDGFHIAMANLNVGRIGIAAQALGI 251
Query 255 AERMLNDALHYAVERKQFGQPIANFQLIQAMLADSKAEIYAAKCMVLDAARRRDEGQNIS 314
AE L A+ YA +R QFG+PIA Q I LAD AA+ +V AA + G N
Sbjct 252 AEAALEHAVDYAKQRVQFGRPIAANQGISFKLADMATRAEAARHLVYHAADLHNRGLNCG 311
Query 315 TEASCAKMFATEMCGRVADRCVQIHGGAGYISEYSIERFYRDVRLFRLYEGTTQVQQIII 374
EAS AK FA++ + A VQI+GG GY+ +Y +ER RD ++ ++YEGT ++Q++II
Sbjct 312 KEASMAKQFASDAAVKAALDAVQIYGGYGYMKDYPVERLLRDAKVTQIYEGTNEIQRLII 371
Query 375 AKNMI 379
+K ++
Sbjct 372 SKYLL 376
>G3KIM8 Acryloyl-CoA reductase (NADH) [Anaerotignum propionicum]
Length=394
Score = 285 bits (730), Expect = 6e-97
Identities = 157/382 (41%), Positives = 237/382 (62%), Gaps = 8/382 (2%)
Query 1 MIRDEGMLQQLLSTIRDFVKNELIPREHEVAEKDCIPEDIIQQMRELGLFGLTIPEEYGG 60
+ R++ ML++L R F + EL P E+ + P + ++M E+GL G+ IP+E+GG
Sbjct 18 LTREQEMLKKLA---RQFAEIELEPVAEEIDREHVFPAENFKKMAEIGLTGIGIPKEFGG 74
Query 61 LGITMEEEVNVAFELGQTSPAFRSLIGTNNGIGSSGLIIDGTEEQKQKYLPRYASGEIIG 120
G E+V E G+ A S++ + I + GT+EQK+ YLPR G +G
Sbjct 75 SGGGTLEKVIAVSEFGKKCMASASILSIHL-IAPQAIYKYGTKEQKETYLPRLTKGGELG 133
Query 121 SFCLTEPEAGSDAASLKTTAVKDGDF--YILNGTKRFITNAPHAATFTVMARTNPAIKGA 178
+F LTEP AGSDA ++KTTA+ D Y+LNGTK FI+ A + A T P KG
Sbjct 134 AFALTEPNAGSDAGAVKTTAILDSQTNEYVLNGTKCFISGGGRAGVLVIFALTEPK-KGL 192
Query 179 GGISAFLVEANTPGITLGKIDQKMGQKGSHTCDVIFENCRVPASALIGGVEGVGFKTAMK 238
G+SA +VE TPG ++GK++ KMG GS T ++IFE+CRVPA+ L+G EG GFK AM+
Sbjct 193 KGMSAIIVEKGTPGFSIGKVESKMGIAGSETAELIFEDCRVPAANLLGK-EGKGFKIAME 251
Query 239 VLDKGRLHIGAYSVGVAERMLNDALHYAVERKQFGQPIANFQLIQAMLADSKAEIYAAKC 298
LD R+ +GA ++G+AE ++ ++ Y ER QFG+PIAN Q IQ +AD + AA+
Sbjct 252 ALDGARIGVGAQAIGIAEGAIDLSVKYVHERIQFGKPIANLQGIQWYIADMATKTAAARA 311
Query 299 MVLDAARRRDEGQNISTEASCAKMFATEMCGRVADRCVQIHGGAGYISEYSIERFYRDVR 358
+V AA D G+ + E++ K+ A+E V + +QIHGG GY+ +Y +ER YRD +
Sbjct 312 LVEFAAYLEDAGKPFTKESAMCKLNASENARFVTNLALQIHGGYGYMKDYPLERMYRDAK 371
Query 359 LFRLYEGTTQVQQIIIAKNMIK 380
+ +YEGT+++ +++IA+ ++K
Sbjct 372 ITEIYEGTSEIHKVVIAREVMK 393
>P9WQG1 Probable acyl-CoA dehydrogenase FadE25 [Mycobacterium
tuberculosis (strain ATCC 25618 / H37Rv)]
Length=389
Score = 281 bits (719), Expect = 2e-95
Identities = 154/372 (41%), Positives = 234/372 (63%), Gaps = 4/372 (1%)
Query 10 QLLSTIRDFVKNELIPREHEVAEKDCIPEDIIQQMRELGLFGLTIPEEYGGLGITMEEEV 69
++ S IR + E+ P EV EK PE+ + + G + IPEEYGG G
Sbjct 21 EMRSAIRALAEKEIAPHAAEVDEKARFPEEALVALNSSGFNAVHIPEEYGGQGADSVATC 80
Query 70 NVAFELGQTSPAFRSLIGTNNGIGSSGLIIDGTEEQKQKYLPRYASGEIIGSFCLTEPEA 129
V E+ + A SLI N +G+ GLI+ G+EE K++ LP A+ + S+ L+E EA
Sbjct 81 IVIEEVARVD-ASASLIPAVNKLGTMGLILRGSEELKKQVLPALAAEGAMASYALSEREA 139
Query 130 GSDAASLKTTAVKDGDFYILNGTKRFITNAPHAATFTVMARTNPAIKGAGGISAFLVEAN 189
GSDAAS++T A DGD +ILNG K +ITN + +TVMA T+P +GA GISAF+V +
Sbjct 140 GSDAASMRTRAKADGDHWILNGAKCWITNGGKSTWYTVMAVTDPD-RGANGISAFMVHKD 198
Query 190 TPGITLGKIDQKMGQKGSHTCDVIFENCRVPASALIGGVEGVGFKTAMKVLDKGRLHIGA 249
G T+G ++K+G KGS T ++ FENCR+P +I G G GFKTA+ LD R IGA
Sbjct 199 DEGFTVGPKERKLGIKGSPTTELYFENCRIPGDRII-GEPGTGFKTALATLDHTRPTIGA 257
Query 250 YSVGVAERMLNDALHYAVERKQFGQPIANFQLIQAMLADSKAEIYAAKCMVLDAARRRDE 309
+VG+A+ L+ A+ Y +RKQFG+ I+ FQ +Q MLAD ++ AA+ MV AA R +
Sbjct 258 QAVGIAQGALDAAIAYTKDRKQFGESISTFQAVQFMLADMAMKVEAARLMVYSAAARAER 317
Query 310 GQ-NISTEASCAKMFATEMCGRVADRCVQIHGGAGYISEYSIERFYRDVRLFRLYEGTTQ 368
G+ ++ ++ +K FA+++ V VQ+ GGAGY +++ +ERF RD ++ ++YEGT Q
Sbjct 318 GEPDLGFISAASKCFASDVAMEVTTDAVQLFGGAGYTTDFPVERFMRDAKITQIYEGTNQ 377
Query 369 VQQIIIAKNMIK 380
+Q++++++ +++
Sbjct 378 IQRVVMSRALLR 389
>P9WQG0 Probable acyl-CoA dehydrogenase fadE25 [Mycobacterium
tuberculosis (strain CDC 1551 / Oshkosh)]
Length=389
Score = 281 bits (719), Expect = 2e-95
Identities = 154/372 (41%), Positives = 234/372 (63%), Gaps = 4/372 (1%)
Query 10 QLLSTIRDFVKNELIPREHEVAEKDCIPEDIIQQMRELGLFGLTIPEEYGGLGITMEEEV 69
++ S IR + E+ P EV EK PE+ + + G + IPEEYGG G
Sbjct 21 EMRSAIRALAEKEIAPHAAEVDEKARFPEEALVALNSSGFNAVHIPEEYGGQGADSVATC 80
Query 70 NVAFELGQTSPAFRSLIGTNNGIGSSGLIIDGTEEQKQKYLPRYASGEIIGSFCLTEPEA 129
V E+ + A SLI N +G+ GLI+ G+EE K++ LP A+ + S+ L+E EA
Sbjct 81 IVIEEVARVD-ASASLIPAVNKLGTMGLILRGSEELKKQVLPALAAEGAMASYALSEREA 139
Query 130 GSDAASLKTTAVKDGDFYILNGTKRFITNAPHAATFTVMARTNPAIKGAGGISAFLVEAN 189
GSDAAS++T A DGD +ILNG K +ITN + +TVMA T+P +GA GISAF+V +
Sbjct 140 GSDAASMRTRAKADGDHWILNGAKCWITNGGKSTWYTVMAVTDPD-RGANGISAFMVHKD 198
Query 190 TPGITLGKIDQKMGQKGSHTCDVIFENCRVPASALIGGVEGVGFKTAMKVLDKGRLHIGA 249
G T+G ++K+G KGS T ++ FENCR+P +I G G GFKTA+ LD R IGA
Sbjct 199 DEGFTVGPKERKLGIKGSPTTELYFENCRIPGDRII-GEPGTGFKTALATLDHTRPTIGA 257
Query 250 YSVGVAERMLNDALHYAVERKQFGQPIANFQLIQAMLADSKAEIYAAKCMVLDAARRRDE 309
+VG+A+ L+ A+ Y +RKQFG+ I+ FQ +Q MLAD ++ AA+ MV AA R +
Sbjct 258 QAVGIAQGALDAAIAYTKDRKQFGESISTFQAVQFMLADMAMKVEAARLMVYSAAARAER 317
Query 310 GQ-NISTEASCAKMFATEMCGRVADRCVQIHGGAGYISEYSIERFYRDVRLFRLYEGTTQ 368
G+ ++ ++ +K FA+++ V VQ+ GGAGY +++ +ERF RD ++ ++YEGT Q
Sbjct 318 GEPDLGFISAASKCFASDVAMEVTTDAVQLFGGAGYTTDFPVERFMRDAKITQIYEGTNQ 377
Query 369 VQQIIIAKNMIK 380
+Q++++++ +++
Sbjct 378 IQRVVMSRALLR 389
>P63428 Probable acyl-CoA dehydrogenase fadE25 [Mycobacterium
bovis (strain ATCC BAA-935 / AF2122/97)]
Length=389
Score = 281 bits (719), Expect = 2e-95
Identities = 154/372 (41%), Positives = 234/372 (63%), Gaps = 4/372 (1%)
Query 10 QLLSTIRDFVKNELIPREHEVAEKDCIPEDIIQQMRELGLFGLTIPEEYGGLGITMEEEV 69
++ S IR + E+ P EV EK PE+ + + G + IPEEYGG G
Sbjct 21 EMRSAIRALAEKEIAPHAAEVDEKARFPEEALVALNSSGFNAVHIPEEYGGQGADSVATC 80
Query 70 NVAFELGQTSPAFRSLIGTNNGIGSSGLIIDGTEEQKQKYLPRYASGEIIGSFCLTEPEA 129
V E+ + A SLI N +G+ GLI+ G+EE K++ LP A+ + S+ L+E EA
Sbjct 81 IVIEEVARVD-ASASLIPAVNKLGTMGLILRGSEELKKQVLPALAAEGAMASYALSEREA 139
Query 130 GSDAASLKTTAVKDGDFYILNGTKRFITNAPHAATFTVMARTNPAIKGAGGISAFLVEAN 189
GSDAAS++T A DGD +ILNG K +ITN + +TVMA T+P +GA GISAF+V +
Sbjct 140 GSDAASMRTRAKADGDHWILNGAKCWITNGGKSTWYTVMAVTDPD-RGANGISAFMVHKD 198
Query 190 TPGITLGKIDQKMGQKGSHTCDVIFENCRVPASALIGGVEGVGFKTAMKVLDKGRLHIGA 249
G T+G ++K+G KGS T ++ FENCR+P +I G G GFKTA+ LD R IGA
Sbjct 199 DEGFTVGPKERKLGIKGSPTTELYFENCRIPGDRII-GEPGTGFKTALATLDHTRPTIGA 257
Query 250 YSVGVAERMLNDALHYAVERKQFGQPIANFQLIQAMLADSKAEIYAAKCMVLDAARRRDE 309
+VG+A+ L+ A+ Y +RKQFG+ I+ FQ +Q MLAD ++ AA+ MV AA R +
Sbjct 258 QAVGIAQGALDAAIAYTKDRKQFGESISTFQAVQFMLADMAMKVEAARLMVYSAAARAER 317
Query 310 GQ-NISTEASCAKMFATEMCGRVADRCVQIHGGAGYISEYSIERFYRDVRLFRLYEGTTQ 368
G+ ++ ++ +K FA+++ V VQ+ GGAGY +++ +ERF RD ++ ++YEGT Q
Sbjct 318 GEPDLGFISAASKCFASDVAMEVTTDAVQLFGGAGYTTDFPVERFMRDAKITQIYEGTNQ 377
Query 369 VQQIIIAKNMIK 380
+Q++++++ +++
Sbjct 378 IQRVVMSRALLR 389
>Q5RAS0 Short-chain specific acyl-CoA dehydrogenase, mitochondrial
[Pongo abelii]
Length=412
Score = 274 bits (701), Expect = 2e-92
Identities = 146/376 (39%), Positives = 231/376 (61%), Gaps = 2/376 (1%)
Query 9 QQLLSTIRDFVKNELIPREHEVAEKDCIPEDIIQQMRELGLFGLTIPEEYGGLGITMEEE 68
Q LL T RDF + EL P +V ++ P +++M LGL + +PEE GG G+
Sbjct 39 QMLLQTCRDFAEKELFPIAAQVDKEHLFPAAQVKKMGGLGLLAMDVPEELGGAGLDYLAY 98
Query 69 VNVAFELGQTSPAFRSLIGTNNGIGSSGLIIDGTEEQKQKYLPRYASGEIIGSFCLTEPE 128
E+ + + ++ NN + ++ G++EQKQK++ + SG+ IG F L+EP
Sbjct 99 AIAMEEISRGCASTGVIMSVNNSLYLGPILKFGSKEQKQKWVTPFTSGDKIGCFALSEPG 158
Query 129 AGSDAASLKTTAVKDGDFYILNGTKRFITNAPHAATFTVMARTNPAIKGAGGISAFLVEA 188
GSDA + TTA +GD ++LNGTK +ITNA A+ V A T+ A++ G ISAFLV
Sbjct 159 NGSDAGAASTTARAEGDSWVLNGTKAWITNAWEASAAVVFASTDRALQNKG-ISAFLVPM 217
Query 189 NTPGITLGKIDQKMGQKGSHTCDVIFENCRVPASALIGGVEGVGFKTAMKVLDKGRLHIG 248
TPG+TLGK + K+G +GS T ++IFE+CR+P +++G G+GFK AM+ LD GR+ I
Sbjct 218 PTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSILGE-PGMGFKIAMQTLDMGRIGIA 276
Query 249 AYSVGVAERMLNDALHYAVERKQFGQPIANFQLIQAMLADSKAEIYAAKCMVLDAARRRD 308
+ ++G+A+ L+ A++YA R FG P+ Q+IQ LAD + +A+ + AA +D
Sbjct 277 SQALGIAQTALDCAVNYAENRMAFGAPLTKLQVIQFKLADMALALESARLLTWRAAMLKD 336
Query 309 EGQNISTEASCAKMFATEMCGRVADRCVQIHGGAGYISEYSIERFYRDVRLFRLYEGTTQ 368
+ EA+ AK+ A+E ++ + +QI GG GY++E ER YRD R+ +YEGT++
Sbjct 337 NKKPFIKEAAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERHYRDARITEIYEGTSE 396
Query 369 VQQIIIAKNMIKEVTS 384
+Q+++IA ++++ S
Sbjct 397 IQRLVIAGHLLRSYRS 412
>P46703 Probable acyl-CoA dehydrogenase fadE25 [Mycobacterium
leprae (strain TN)]
Length=389
Score = 273 bits (697), Expect = 5e-92
Identities = 150/372 (40%), Positives = 234/372 (63%), Gaps = 4/372 (1%)
Query 10 QLLSTIRDFVKNELIPREHEVAEKDCIPEDIIQQMRELGLFGLTIPEEYGGLGITMEEEV 69
+L +TIR + E+ P +V ++ PE+ + + G + +PEEYGG G
Sbjct 21 ELRATIRALAEKEIAPHAADVDQRARFPEEALAALNASGFNAIHVPEEYGGQGADSVAAC 80
Query 70 NVAFELGQTSPAFRSLIGTNNGIGSSGLIIDGTEEQKQKYLPRYASGEIIGSFCLTEPEA 129
V E+ + A SLI N +G+ GLI+ G+EE K++ LP A+ + S+ L+E EA
Sbjct 81 IVIEEVARVD-ASASLIPAVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREA 139
Query 130 GSDAASLKTTAVKDGDFYILNGTKRFITNAPHAATFTVMARTNPAIKGAGGISAFLVEAN 189
GSDAAS++T A DGD +ILNG K +ITN + +TVMA T+P KGA GISAF+V +
Sbjct 140 GSDAASMRTRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPD-KGANGISAFIVHKD 198
Query 190 TPGITLGKIDQKMGQKGSHTCDVIFENCRVPASALIGGVEGVGFKTAMKVLDKGRLHIGA 249
G ++G ++K+G KGS T ++ F+ CR+P +I G G GFKTA+ LD R IGA
Sbjct 199 DEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRII-GEPGTGFKTALATLDHTRPTIGA 257
Query 250 YSVGVAERMLNDALHYAVERKQFGQPIANFQLIQAMLADSKAEIYAAKCMVLDAARRRDE 309
+VG+A+ L+ A+ Y +RKQFG+ I+ FQ IQ MLAD ++ AA+ +V AA R +
Sbjct 258 QAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAER 317
Query 310 GQ-NISTEASCAKMFATEMCGRVADRCVQIHGGAGYISEYSIERFYRDVRLFRLYEGTTQ 368
G+ ++ ++ +K FA+++ V VQ+ GGAGY S++ +ERF RD ++ ++YEGT Q
Sbjct 318 GEPDLGFISAASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQ 377
Query 369 VQQIIIAKNMIK 380
+Q++++++ +++
Sbjct 378 IQRVVMSRALLR 389
>P16219 Short-chain specific acyl-CoA dehydrogenase, mitochondrial
[Homo sapiens]
Length=412
Score = 272 bits (695), Expect = 2e-91
Identities = 145/376 (39%), Positives = 230/376 (61%), Gaps = 2/376 (1%)
Query 9 QQLLSTIRDFVKNELIPREHEVAEKDCIPEDIIQQMRELGLFGLTIPEEYGGLGITMEEE 68
Q LL T RDF + EL P +V ++ P +++M LGL + +PEE GG G+
Sbjct 39 QMLLQTCRDFAEKELFPIAAQVDKEHLFPAAQVKKMGGLGLLAMDVPEELGGAGLDYLAY 98
Query 69 VNVAFELGQTSPAFRSLIGTNNGIGSSGLIIDGTEEQKQKYLPRYASGEIIGSFCLTEPE 128
E+ + + ++ NN + ++ G++EQKQ ++ + SG+ IG F L+EP
Sbjct 99 AIAMEEISRGCASTGVIMSVNNSLYLGPILKFGSKEQKQAWVTPFTSGDKIGCFALSEPG 158
Query 129 AGSDAASLKTTAVKDGDFYILNGTKRFITNAPHAATFTVMARTNPAIKGAGGISAFLVEA 188
GSDA + TTA +GD ++LNGTK +ITNA A+ V A T+ A++ G ISAFLV
Sbjct 159 NGSDAGAASTTARAEGDSWVLNGTKAWITNAWEASAAVVFASTDRALQNKG-ISAFLVPM 217
Query 189 NTPGITLGKIDQKMGQKGSHTCDVIFENCRVPASALIGGVEGVGFKTAMKVLDKGRLHIG 248
TPG+TLGK + K+G +GS T ++IFE+CR+P +++G G+GFK AM+ LD GR+ I
Sbjct 218 PTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSILGE-PGMGFKIAMQTLDMGRIGIA 276
Query 249 AYSVGVAERMLNDALHYAVERKQFGQPIANFQLIQAMLADSKAEIYAAKCMVLDAARRRD 308
+ ++G+A+ L+ A++YA R FG P+ Q+IQ LAD + +A+ + AA +D
Sbjct 277 SQALGIAQTALDCAVNYAENRMAFGAPLTKLQVIQFKLADMALALESARLLTWRAAMLKD 336
Query 309 EGQNISTEASCAKMFATEMCGRVADRCVQIHGGAGYISEYSIERFYRDVRLFRLYEGTTQ 368
+ EA+ AK+ A+E ++ + +QI GG GY++E ER YRD R+ +YEGT++
Sbjct 337 NKKPFIKEAAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERHYRDARITEIYEGTSE 396
Query 369 VQQIIIAKNMIKEVTS 384
+Q+++IA ++++ S
Sbjct 397 IQRLVIAGHLLRSYRS 412
>P52042 Acyl-CoA dehydrogenase, short-chain specific [Clostridium
acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG
5710 / VKM B-1787)]
Length=379
Score = 263 bits (673), Expect = 1e-88
Identities = 142/380 (37%), Positives = 230/380 (61%), Gaps = 5/380 (1%)
Query 1 MIRDEGMLQQLLSTIRDFVKNELIPREHEVAEKDCIPEDIIQQMRELGLFGLTIPEEYGG 60
+ R++ +++Q+ +R+F +NE+ P E+ E + P + +++M + G+ G+ +EYGG
Sbjct 5 LTREQELVRQM---VREFAENEVKPIAAEIDETERFPMENVKKMGQYGMMGIPFSKEYGG 61
Query 61 LGITMEEEVNVAFELGQTSPAFRSLIGTNNGIGSSGLIIDGTEEQKQKYLPRYASGEIIG 120
G + + EL + ++ + + +S + GTEEQKQKYL A GE IG
Sbjct 62 AGGDVLSYIIAVEELSKVCGTTGVILSAHTSLCASLINEHGTEEQKQKYLVPLAKGEKIG 121
Query 121 SFCLTEPEAGSDAASLKTTAVKDGDFYILNGTKRFITNAPHAATFTVMARTNPAIKGAGG 180
++ LTEP AG+D+ + +T AV +GD Y++NG+K FITN A TF + A T+ KG G
Sbjct 122 AYGLTEPNAGTDSGAQQTVAVLEGDHYVINGSKIFITNGGVADTFVIFAMTDRT-KGTKG 180
Query 181 ISAFLVEANTPGITLGKIDQKMGQKGSHTCDVIFENCRVPASALIGGVEGVGFKTAMKVL 240
ISAF++E G ++GK++QK+G + S T +++FE+ VP +IG EG GF AMK L
Sbjct 181 ISAFIIEKGFKGFSIGKVEQKLGIRASSTTELVFEDMIVPVENMIGK-EGKGFPIAMKTL 239
Query 241 DKGRLHIGAYSVGVAERMLNDALHYAVERKQFGQPIANFQLIQAMLADSKAEIYAAKCMV 300
D GR+ I A ++G+AE N+A Y ERKQFG+ + FQ + M+AD I +A+ +V
Sbjct 240 DGGRIGIAAQALGIAEGAFNEARAYMKERKQFGRSLDKFQGLAWMMADMDVAIESARYLV 299
Query 301 LDAARRRDEGQNISTEASCAKMFATEMCGRVADRCVQIHGGAGYISEYSIERFYRDVRLF 360
AA + G + +A+ AK+ A + V + VQ+ GG GY +Y +ER RD ++
Sbjct 300 YKAAYLKQAGLPYTVDAARAKLHAANVAMDVTTKAVQLFGGYGYTKDYPVERMMRDAKIT 359
Query 361 RLYEGTTQVQQIIIAKNMIK 380
+YEGT++VQ+++I+ + +
Sbjct 360 EIYEGTSEVQKLVISGKIFR 379
>P15651 Short-chain specific acyl-CoA dehydrogenase, mitochondrial
[Rattus norvegicus]
Length=412
Score = 261 bits (668), Expect = 2e-87
Identities = 138/376 (37%), Positives = 228/376 (61%), Gaps = 2/376 (1%)
Query 9 QQLLSTIRDFVKNELIPREHEVAEKDCIPEDIIQQMRELGLFGLTIPEEYGGLGITMEEE 68
Q L T RDF + EL+P ++ ++ P +++M ELGL + +PEE G G+
Sbjct 39 QMLRQTCRDFAEKELVPIAAQLDKEHLFPTSQVKKMGELGLLAMDVPEELSGAGLDYLAY 98
Query 69 VNVAFELGQTSPAFRSLIGTNNGIGSSGLIIDGTEEQKQKYLPRYASGEIIGSFCLTEPE 128
E+ + + ++ NN + ++ G+ +QKQ+++ + +G+ IG F L+EP
Sbjct 99 SIALEEISRGCASTGVIMSVNNSLYLGPILKFGSSQQKQQWITPFTNGDKIGCFALSEPG 158
Query 129 AGSDAASLKTTAVKDGDFYILNGTKRFITNAPHAATFTVMARTNPAIKGAGGISAFLVEA 188
GSDA + TTA ++GD ++LNGTK +ITN+ A+ V A T+ + + G ISAFLV
Sbjct 159 NGSDAGAASTTAREEGDSWVLNGTKAWITNSWEASATVVFASTDRSRQNKG-ISAFLVPM 217
Query 189 NTPGITLGKIDQKMGQKGSHTCDVIFENCRVPASALIGGVEGVGFKTAMKVLDKGRLHIG 248
TPG+TLGK + K+G + S T ++IFE+CR+P L+G G+GFK AM+ LD GR+ I
Sbjct 218 PTPGLTLGKKEDKLGIRASSTANLIFEDCRIPKENLLGE-PGMGFKIAMQTLDMGRIGIA 276
Query 249 AYSVGVAERMLNDALHYAVERKQFGQPIANFQLIQAMLADSKAEIYAAKCMVLDAARRRD 308
+ ++G+A+ L+ A+ YA R FG P+ Q IQ LAD + +A+ + AA +D
Sbjct 277 SQALGIAQASLDCAVKYAENRHAFGAPLTKLQNIQFKLADMALALESARLLTWRAAMLKD 336
Query 309 EGQNISTEASCAKMFATEMCGRVADRCVQIHGGAGYISEYSIERFYRDVRLFRLYEGTTQ 368
+ + E++ AK+ A+E ++ + +QI GG GY++E ER+YRD R+ +YEGT++
Sbjct 337 NKKPFTKESAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERYYRDARITEIYEGTSE 396
Query 369 VQQIIIAKNMIKEVTS 384
+Q+++IA ++++ S
Sbjct 397 IQRLVIAGHLLRSYRS 412
>Q3ZBF6 Short-chain specific acyl-CoA dehydrogenase, mitochondrial
[Bos taurus]
Length=412
Score = 261 bits (668), Expect = 2e-87
Identities = 143/376 (38%), Positives = 224/376 (60%), Gaps = 2/376 (1%)
Query 9 QQLLSTIRDFVKNELIPREHEVAEKDCIPEDIIQQMRELGLFGLTIPEEYGGLGITMEEE 68
Q L T RDF + EL P +V ++ P +++M ELGL + +PEE G G+
Sbjct 39 QMLRQTCRDFAEKELFPIAAQVDKEHRFPAAQVKKMGELGLMAMNVPEELSGAGLDYLAY 98
Query 69 VNVAFELGQTSPAFRSLIGTNNGIGSSGLIIDGTEEQKQKYLPRYASGEIIGSFCLTEPE 128
E+ + + ++ NN + ++ GT+EQKQ+++ + SG+ IG F L+EP
Sbjct 99 SIAMEEISRGCASTGVIMSVNNSLYLGPILKFGTKEQKQQWVAPFTSGDKIGCFALSEPG 158
Query 129 AGSDAASLKTTAVKDGDFYILNGTKRFITNAPHAATFTVMARTNPAIKGAGGISAFLVEA 188
GSDA + TTA DGD ++L+GTK +ITNA A+ V A T+ ++ G ISAFLV
Sbjct 159 NGSDAGAAATTARADGDSWVLSGTKAWITNAWEASAVVVFASTDRSLHNKG-ISAFLVPM 217
Query 189 NTPGITLGKIDQKMGQKGSHTCDVIFENCRVPASALIGGVEGVGFKTAMKVLDKGRLHIG 248
TPG+TLGK + K+G + S T ++IFE+ R+P +L+G G+GFK AM+ LD GR+ I
Sbjct 218 PTPGLTLGKKEDKLGIRASSTANLIFEDRRIPKDSLLGE-PGLGFKIAMQTLDTGRIGIA 276
Query 249 AYSVGVAERMLNDALHYAVERKQFGQPIANFQLIQAMLADSKAEIYAAKCMVLDAARRRD 308
+ ++G+A+ L+ A+ YA R FG P+ Q IQ LAD + +A+ + AA +D
Sbjct 277 SQALGIAQAALDCAVTYAENRSAFGAPLTKLQAIQFKLADMALALESARLLTWRAAMLKD 336
Query 309 EGQNISTEASCAKMFATEMCGRVADRCVQIHGGAGYISEYSIERFYRDVRLFRLYEGTTQ 368
+ + EA+ AK+ A+E + + +QI GG GY+ E ER YRD R+ +YEGT++
Sbjct 337 NKKPFTKEAAMAKLAASEAATAITHQAMQILGGMGYVKEMPAERHYRDARITEIYEGTSE 396
Query 369 VQQIIIAKNMIKEVTS 384
+Q++++A +++K S
Sbjct 397 IQRLVVAGHLLKSYRS 412
>Q07417 Short-chain specific acyl-CoA dehydrogenase, mitochondrial
[Mus musculus]
Length=412
Score = 261 bits (667), Expect = 3e-87
Identities = 138/376 (37%), Positives = 227/376 (60%), Gaps = 2/376 (1%)
Query 9 QQLLSTIRDFVKNELIPREHEVAEKDCIPEDIIQQMRELGLFGLTIPEEYGGLGITMEEE 68
Q L T RDF + EL+P ++ + P +++M ELGL + +PEE G G+
Sbjct 39 QMLRQTCRDFAEKELVPIAAQLDREHLFPTAQVKKMGELGLLAMDVPEELSGAGLDYLAY 98
Query 69 VNVAFELGQTSPAFRSLIGTNNGIGSSGLIIDGTEEQKQKYLPRYASGEIIGSFCLTEPE 128
E+ + + ++ NN + ++ G+ +QKQ+++ + +G+ IG F L+EP
Sbjct 99 SIALEEISRACASTGVIMSVNNSLYLGPILKFGSAQQKQQWITPFTNGDKIGCFALSEPG 158
Query 129 AGSDAASLKTTAVKDGDFYILNGTKRFITNAPHAATFTVMARTNPAIKGAGGISAFLVEA 188
GSDA + TTA ++GD ++LNGTK +ITN+ A+ V A T+ + + G ISAFLV
Sbjct 159 NGSDAGAASTTAREEGDSWVLNGTKAWITNSWEASATVVFASTDRSRQNKG-ISAFLVPM 217
Query 189 NTPGITLGKIDQKMGQKGSHTCDVIFENCRVPASALIGGVEGVGFKTAMKVLDKGRLHIG 248
TPG+TLGK + K+G + S T ++IFE+CR+P L+G G+GFK AM+ LD GR+ I
Sbjct 218 PTPGLTLGKKEDKLGIRASSTANLIFEDCRIPKENLLGE-PGMGFKIAMQTLDMGRIGIA 276
Query 249 AYSVGVAERMLNDALHYAVERKQFGQPIANFQLIQAMLADSKAEIYAAKCMVLDAARRRD 308
+ ++G+A+ L+ A+ YA R FG P+ Q IQ LAD + +A+ + AA +D
Sbjct 277 SQALGIAQASLDCAVKYAENRNAFGAPLTKLQNIQFKLADMALALESARLLTWRAAMLKD 336
Query 309 EGQNISTEASCAKMFATEMCGRVADRCVQIHGGAGYISEYSIERFYRDVRLFRLYEGTTQ 368
+ + E++ AK+ A+E ++ + +QI GG GY++E ER+YRD R+ +YEGT++
Sbjct 337 NKKPFTKESAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERYYRDARITEIYEGTSE 396
Query 369 VQQIIIAKNMIKEVTS 384
+Q+++IA ++++ S
Sbjct 397 IQRLVIAGHLLRSYRS 412
Lambda K H a alpha
0.321 0.137 0.393 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1736784
Database: 5450b98910b25653128b33cb82b8aae7.SwissProt.fasta
Posted date: May 18, 2024 4:45 PM
Number of letters in database: 5,904
Number of sequences in database: 15
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
