BLASTP 2.12.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: e0640296e72129ef29a65fd580adf489.SwissProt.fasta
           13 sequences; 5,166 total letters



Query= ACIAD1706

Length=402
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q43974 Beta-ketoadipyl-CoA thiolase [Acinetobacter baylyi (strain...  781     0.0   
Q43935 Beta-ketoadipyl-CoA thiolase [Acinetobacter baylyi (strain...  778     0.0   
Q8VPF1 Beta-ketoadipyl-CoA thiolase [Pseudomonas knackmussii (str...  543     0.0   
Q9I6R0 Beta-ketoadipyl-CoA thiolase [Pseudomonas aeruginosa (stra...  523     0.0   
Q51956 Beta-ketoadipyl-CoA thiolase [Pseudomonas putida]              507     0.0   
P0C7L2 3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA thiolase [Esc...  492     9e-178
P0C7L3 Beta-ketoadipyl-CoA thiolase [Escherichia coli]                491     1e-177
Q9ZHI1 Acetyl-CoA acetyltransferase [Chromobacterium violaceum (s...  335     4e-116
Q9I2A8 Acetyl-CoA acetyltransferase [Pseudomonas aeruginosa (stra...  333     2e-115
Q0AVM3 Acetyl-CoA acetyltransferase [Syntrophomonas wolfei subsp....  330     2e-114
P45369 Acetyl-CoA acetyltransferase [Allochromatium vinosum (stra...  324     8e-112
P45359 Acetyl-CoA acetyltransferase [Clostridium acetobutylicum (...  323     1e-111
P14611 Acetyl-CoA acetyltransferase [Cupriavidus necator (strain ...  323     1e-111


>Q43974 Beta-ketoadipyl-CoA thiolase [Acinetobacter baylyi (strain 
ATCC 33305 / BD413 / ADP1)]
Length=401

 Score = 781 bits (2018),  Expect = 0.0
 Identities = 401/401 (100%), Positives = 401/401 (100%), Gaps = 0/401 (0%)

Query  1    MKHAYIVDAIRTPFGRYAGGLAAVRADDLGAIPIAALIERNPSVNWAQVDDVIYGCANQA  60
            MKHAYIVDAIRTPFGRYAGGLAAVRADDLGAIPIAALIERNPSVNWAQVDDVIYGCANQA
Sbjct  1    MKHAYIVDAIRTPFGRYAGGLAAVRADDLGAIPIAALIERNPSVNWAQVDDVIYGCANQA  60

Query  61   GEDNRNVGRMSALLAGLPVEVPATTVNRLCGSSLDAIAMAARAIKAGEAHLIIAGGVESM  120
            GEDNRNVGRMSALLAGLPVEVPATTVNRLCGSSLDAIAMAARAIKAGEAHLIIAGGVESM
Sbjct  61   GEDNRNVGRMSALLAGLPVEVPATTVNRLCGSSLDAIAMAARAIKAGEAHLIIAGGVESM  120

Query  121  SRAPYVMGKSEGAFGRTQKIEDTTMGWRFINPKLKAMYGVDTMPQTAENVAEQFGIQRED  180
            SRAPYVMGKSEGAFGRTQKIEDTTMGWRFINPKLKAMYGVDTMPQTAENVAEQFGIQRED
Sbjct  121  SRAPYVMGKSEGAFGRTQKIEDTTMGWRFINPKLKAMYGVDTMPQTAENVAEQFGIQRED  180

Query  181  QDQFAYTSQQRTAAAQAKGYFAKEIVPVTIPQRKGEPVVIDTDEHPRASTTLEGLAKLKG  240
            QDQFAYTSQQRTAAAQAKGYFAKEIVPVTIPQRKGEPVVIDTDEHPRASTTLEGLAKLKG
Sbjct  181  QDQFAYTSQQRTAAAQAKGYFAKEIVPVTIPQRKGEPVVIDTDEHPRASTTLEGLAKLKG  240

Query  241  VVKPEGSVTAGNASGINDGAAAVLIASDEAVAQYQLKARAKIIASTTVGIEPRIMGFAPA  300
            VVKPEGSVTAGNASGINDGAAAVLIASDEAVAQYQLKARAKIIASTTVGIEPRIMGFAPA
Sbjct  241  VVKPEGSVTAGNASGINDGAAAVLIASDEAVAQYQLKARAKIIASTTVGIEPRIMGFAPA  300

Query  301  PAIKKLLKQANLTLDQMDVIELNEAFAAQALACTRDLGLADDDARVNPNGGAIALGHPLG  360
            PAIKKLLKQANLTLDQMDVIELNEAFAAQALACTRDLGLADDDARVNPNGGAIALGHPLG
Sbjct  301  PAIKKLLKQANLTLDQMDVIELNEAFAAQALACTRDLGLADDDARVNPNGGAIALGHPLG  360

Query  361  ASGARLVTTALNQLEQSGGKYALCSMCIGVGQGIALIIERV  401
            ASGARLVTTALNQLEQSGGKYALCSMCIGVGQGIALIIERV
Sbjct  361  ASGARLVTTALNQLEQSGGKYALCSMCIGVGQGIALIIERV  401


>Q43935 Beta-ketoadipyl-CoA thiolase [Acinetobacter baylyi (strain 
ATCC 33305 / BD413 / ADP1)]
Length=401

 Score = 778 bits (2010),  Expect = 0.0
 Identities = 400/401 (99%), Positives = 400/401 (99%), Gaps = 0/401 (0%)

Query  1    MKHAYIVDAIRTPFGRYAGGLAAVRADDLGAIPIAALIERNPSVNWAQVDDVIYGCANQA  60
            MKHAYIVDAIRTPFGRYAGGLAAVRADDLGAIPIAALIERNPSVNWAQVDDVIYGCANQA
Sbjct  1    MKHAYIVDAIRTPFGRYAGGLAAVRADDLGAIPIAALIERNPSVNWAQVDDVIYGCANQA  60

Query  61   GEDNRNVGRMSALLAGLPVEVPATTVNRLCGSSLDAIAMAARAIKAGEAHLIIAGGVESM  120
            GEDNRNVGRMSALLAGLPVEVPATTVNRLCGSSLDAIAMAARAIKAGEAHLIIAGGVESM
Sbjct  61   GEDNRNVGRMSALLAGLPVEVPATTVNRLCGSSLDAIAMAARAIKAGEAHLIIAGGVESM  120

Query  121  SRAPYVMGKSEGAFGRTQKIEDTTMGWRFINPKLKAMYGVDTMPQTAENVAEQFGIQRED  180
            SRAPYVMGKSEGAFGRTQKIEDTTMGWRFINPKLKAMYGVDTMPQTAENVAEQFGIQRED
Sbjct  121  SRAPYVMGKSEGAFGRTQKIEDTTMGWRFINPKLKAMYGVDTMPQTAENVAEQFGIQRED  180

Query  181  QDQFAYTSQQRTAAAQAKGYFAKEIVPVTIPQRKGEPVVIDTDEHPRASTTLEGLAKLKG  240
            QDQFAYTSQQRTAAAQAKGYFAKEIVPVTIPQRKGEPVVI TDEHPRASTTLEGLAKLKG
Sbjct  181  QDQFAYTSQQRTAAAQAKGYFAKEIVPVTIPQRKGEPVVIATDEHPRASTTLEGLAKLKG  240

Query  241  VVKPEGSVTAGNASGINDGAAAVLIASDEAVAQYQLKARAKIIASTTVGIEPRIMGFAPA  300
            VVKPEGSVTAGNASGINDGAAAVLIASDEAVAQYQLKARAKIIASTTVGIEPRIMGFAPA
Sbjct  241  VVKPEGSVTAGNASGINDGAAAVLIASDEAVAQYQLKARAKIIASTTVGIEPRIMGFAPA  300

Query  301  PAIKKLLKQANLTLDQMDVIELNEAFAAQALACTRDLGLADDDARVNPNGGAIALGHPLG  360
            PAIKKLLKQANLTLDQMDVIELNEAFAAQALACTRDLGLADDDARVNPNGGAIALGHPLG
Sbjct  301  PAIKKLLKQANLTLDQMDVIELNEAFAAQALACTRDLGLADDDARVNPNGGAIALGHPLG  360

Query  361  ASGARLVTTALNQLEQSGGKYALCSMCIGVGQGIALIIERV  401
            ASGARLVTTALNQLEQSGGKYALCSMCIGVGQGIALIIERV
Sbjct  361  ASGARLVTTALNQLEQSGGKYALCSMCIGVGQGIALIIERV  401


>Q8VPF1 Beta-ketoadipyl-CoA thiolase [Pseudomonas knackmussii 
(strain DSM 6978 / LMG 23759 / B13)]
Length=401

 Score = 543 bits (1399),  Expect = 0.0
 Identities = 265/400 (66%), Positives = 323/400 (81%), Gaps = 1/400 (0%)

Query  2    KHAYIVDAIRTPFGRYAGGLAAVRADDLGAIPIAALIERNPSVNWAQVDDVIYGCANQAG  61
            +  YI DA+RTP GR+ G LAAVRADDL A+P+ AL+ERNP V+W+Q+D+V  GCANQAG
Sbjct  3    REVYICDAVRTPIGRFGGSLAAVRADDLAAVPVKALVERNPQVDWSQLDEVYLGCANQAG  62

Query  62   EDNRNVGRMSALLAGLPVEVPATTVNRLCGSSLDAIAMAARAIKAGEAHLIIAGGVESMS  121
            EDNRNV RM+ LLAGLP  VP  T+NRLC S +DA+  A RAI +GEA L+IAGGVESMS
Sbjct  63   EDNRNVARMALLLAGLPDSVPGVTLNRLCASGMDAVGTAFRAIASGEAELVIAGGVESMS  122

Query  122  RAPYVMGKSEGAFGRTQKIEDTTMGWRFINPKLKAMYGVDTMPQTAENVAEQFGIQREDQ  181
            RAPYVMGK++ AFGR QKIEDTT+GWRFINP +KA YGVD MP+TA+NVA+ + + R DQ
Sbjct  123  RAPYVMGKADSAFGRGQKIEDTTIGWRFINPLMKAQYGVDAMPETADNVADDYKVSRADQ  182

Query  182  DQFAYTSQQRTAAAQAKGYFAKEIVPVTIPQRKGEPVVIDTDEHPRASTTLEGLAKLKGV  241
            D FA  SQQ    AQA GYFA+EIVPV I  +KGE  V+D DEH R  TTLE LAKLK V
Sbjct  183  DAFALRSQQLAGRAQAAGYFAEEIVPVVIKGKKGE-TVVDADEHLRPDTTLEALAKLKPV  241

Query  242  VKPEGSVTAGNASGINDGAAAVLIASDEAVAQYQLKARAKIIASTTVGIEPRIMGFAPAP  301
              P+ +VTAGNASG+NDG+ A+++AS EAV ++ LKARAK++   + G+ PR+MG  P P
Sbjct  242  NGPDKTVTAGNASGVNDGSVALILASAEAVKKHGLKARAKVLGMASAGVAPRVMGIGPVP  301

Query  302  AIKKLLKQANLTLDQMDVIELNEAFAAQALACTRDLGLADDDARVNPNGGAIALGHPLGA  361
            A++KLL++ NL++   DVIELNEAFAAQ LA TR+LG+ADDDARVNPNGGAIALGHPLGA
Sbjct  302  AVRKLLERLNLSVADFDVIELNEAFAAQGLAVTRELGIADDDARVNPNGGAIALGHPLGA  361

Query  362  SGARLVTTALNQLEQSGGKYALCSMCIGVGQGIALIIERV  401
            SGARLV TA++QLE+SGG+  LC+MC+GVGQG+AL +ERV
Sbjct  362  SGARLVLTAVHQLEKSGGQRGLCTMCVGVGQGVALAVERV  401


 Score = 20.8 bits (42),  Expect = 0.87
 Identities = 40/142 (28%), Positives = 55/142 (39%), Gaps = 14/142 (10%)

Query  1    MKHAYIVDAIRTPFGRYAGGLAAVRAD-DLGAIPIAALIERNPSVNWAQ---VDDVIYGC  56
            MK  Y VDA+       A      RAD D  A+    L  R  +  +     V  VI G 
Sbjct  155  MKAQYGVDAMPETADNVADDYKVSRADQDAFALRSQQLAGRAQAAGYFAEEIVPVVIKGK  214

Query  57   ANQ----AGEDNRNVGRMSALLAGLPVEVPATTV--NRLCGSSLDAIAMAARAIKAGEAH  110
              +    A E  R    + AL    PV  P  TV      G +  ++A+   + +A + H
Sbjct  215  KGETVVDADEHLRPDTTLEALAKLKPVNGPDKTVTAGNASGVNDGSVALILASAEAVKKH  274

Query  111  LIIAG----GVESMSRAPYVMG  128
             + A     G+ S   AP VMG
Sbjct  275  GLKARAKVLGMASAGVAPRVMG  296


>Q9I6R0 Beta-ketoadipyl-CoA thiolase [Pseudomonas aeruginosa (strain 
ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 
12228 / 1C / PRS 101 / PAO1)]
Length=401

 Score = 523 bits (1348),  Expect = 0.0
 Identities = 255/400 (64%), Positives = 315/400 (79%), Gaps = 1/400 (0%)

Query  2    KHAYIVDAIRTPFGRYAGGLAAVRADDLGAIPIAALIERNPSVNWAQVDDVIYGCANQAG  61
            +  +I DA+RTP GR+ G L+AVRADDL A+P+ AL+ERNP V+W+ +D+V  GCANQAG
Sbjct  3    REVFICDAVRTPIGRFGGSLSAVRADDLAAVPLKALVERNPGVDWSALDEVFLGCANQAG  62

Query  62   EDNRNVGRMSALLAGLPVEVPATTVNRLCGSSLDAIAMAARAIKAGEAHLIIAGGVESMS  121
            EDNRNV RM+ LLAGLP  VP  T+NRLC S +DAI  A RAI  GE  L IAGGVESMS
Sbjct  63   EDNRNVARMALLLAGLPESVPGVTLNRLCASGMDAIGTAFRAIACGEMELAIAGGVESMS  122

Query  122  RAPYVMGKSEGAFGRTQKIEDTTMGWRFINPKLKAMYGVDTMPQTAENVAEQFGIQREDQ  181
            RAPYVMGK++ AFGR QKIEDTT+GWRF+NP +K  YG+D MPQTA+NVA+ + + R DQ
Sbjct  123  RAPYVMGKADSAFGRGQKIEDTTIGWRFVNPLMKEQYGIDPMPQTADNVADDYRVSRADQ  182

Query  182  DQFAYTSQQRTAAAQAKGYFAKEIVPVTIPQRKGEPVVIDTDEHPRASTTLEGLAKLKGV  241
            D FA  SQQR   AQ  G+FA+EIVPVTI  RKG+  +++ DEHPR  TTLE LA+LK V
Sbjct  183  DAFALRSQQRAGRAQEAGFFAEEIVPVTIRGRKGD-TLVEHDEHPRPDTTLEALARLKPV  241

Query  242  VKPEGSVTAGNASGINDGAAAVLIASDEAVAQYQLKARAKIIASTTVGIEPRIMGFAPAP  301
              PE +VTAGNASG+NDGAAA+++AS EAV ++ L  RA+++   + G+ PRIMG  P P
Sbjct  242  NGPEKTVTAGNASGVNDGAAALVLASAEAVEKHGLTPRARVLGMASAGVAPRIMGIGPVP  301

Query  302  AIKKLLKQANLTLDQMDVIELNEAFAAQALACTRDLGLADDDARVNPNGGAIALGHPLGA  361
            A++KLL++ +L +D  DVIELNEAFA+Q LAC R+LG+ADD  +VNPNGGAIALGHPLG 
Sbjct  302  AVRKLLRRLDLAIDAFDVIELNEAFASQGLACLRELGVADDSEKVNPNGGAIALGHPLGM  361

Query  362  SGARLVTTALNQLEQSGGKYALCSMCIGVGQGIALIIERV  401
            SGARLV TAL+QLE+SGG+  L +MC+GVGQG+AL IERV
Sbjct  362  SGARLVLTALHQLEKSGGRRGLATMCVGVGQGLALAIERV  401


>Q51956 Beta-ketoadipyl-CoA thiolase [Pseudomonas putida]
Length=400

 Score = 507 bits (1305),  Expect = 0.0
 Identities = 248/401 (62%), Positives = 311/401 (78%), Gaps = 1/401 (0%)

Query  1    MKHAYIVDAIRTPFGRYAGGLAAVRADDLGAIPIAALIERNPSVNWAQVDDVIYGCANQA  60
            M+  +I DAIRTP GR+ G LA VRADDL A+P+ ALIE NP+V W QVD+V +GCANQA
Sbjct  1    MRDVFICDAIRTPIGRFGGALAGVRADDLAAVPLKALIEPNPAVQWDQVDEVFFGCANQA  60

Query  61   GEDNRNVGRMSALLAGLPVEVPATTVNRLCGSSLDAIAMAARAIKAGEAHLIIAGGVESM  120
            GEDNRNV RM+ LLAGLP  +P  T+NRLC S +DAI  A RAI +GE  L IAGGVESM
Sbjct  61   GEDNRNVARMALLLAGLPESIPGVTLNRLCASGMDAIGTAFRAIASGEMELAIAGGVESM  120

Query  121  SRAPYVMGKSEGAFGRTQKIEDTTMGWRFINPKLKAMYGVDTMPQTAENVAEQFGIQRED  180
            SRAP+VMGK+E  + R  K+EDTT+GWRFINP +K+ YGVD+MP+TA+NVA+ + + R D
Sbjct  121  SRAPFVMGKAESGYSRNMKLEDTTIGWRFINPLMKSQYGVDSMPETADNVADDYQVSRAD  180

Query  181  QDQFAYTSQQRTAAAQAKGYFAKEIVPVTIPQRKGEPVVIDTDEHPRASTTLEGLAKLKG  240
            QD FA  SQQ+ AAAQA G+FA+EIVPV I  +KGE  +++ DEH R  TTLE L KLK 
Sbjct  181  QDAFALRSQQKAAAAQAAGFFAEEIVPVRIAHKKGE-TIVERDEHLRPETTLEALTKLKP  239

Query  241  VVKPEGSVTAGNASGINDGAAAVLIASDEAVAQYQLKARAKIIASTTVGIEPRIMGFAPA  300
            V  P+ +VTAGNASG+NDGAAA+++AS EAV ++ L  RA+++   + G+ PR+MG  P 
Sbjct  240  VNGPDKTVTAGNASGVNDGAAALILASAEAVKKHGLTPRARVLGMASGGVAPRVMGIGPV  299

Query  301  PAIKKLLKQANLTLDQMDVIELNEAFAAQALACTRDLGLADDDARVNPNGGAIALGHPLG  360
            PA++KL ++  + +   DVIELNEAFA+Q LA  R+LG+ADD  +VNPNGGAIALGHPLG
Sbjct  300  PAVRKLTERLGVAVSDFDVIELNEAFASQGLAVLRELGVADDAPQVNPNGGAIALGHPLG  359

Query  361  ASGARLVTTALNQLEQSGGKYALCSMCIGVGQGIALIIERV  401
             SGARLV TAL+QLE+SGG+  L +MC+GVGQG+AL IERV
Sbjct  360  MSGARLVLTALHQLEKSGGRKGLATMCVGVGQGLALAIERV  400


>P0C7L2 3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA thiolase 
[Escherichia coli (strain K12)]
Length=401

 Score = 492 bits (1266),  Expect = 9e-178
 Identities = 246/401 (61%), Positives = 300/401 (75%), Gaps = 0/401 (0%)

Query  1    MKHAYIVDAIRTPFGRYAGGLAAVRADDLGAIPIAALIERNPSVNWAQVDDVIYGCANQA  60
            M+ A+I D IRTP GRY G L++VRADDL AIP+  L+ RNP ++   +DDVI GCANQA
Sbjct  1    MREAFICDGIRTPIGRYGGALSSVRADDLAAIPLRELLVRNPRLDAECIDDVILGCANQA  60

Query  61   GEDNRNVGRMSALLAGLPVEVPATTVNRLCGSSLDAIAMAARAIKAGEAHLIIAGGVESM  120
            GEDNRNV RM+ LLAGLP  V  TT+NRLCGS LDA+  AARAIKAG+  L+IAGGVESM
Sbjct  61   GEDNRNVARMATLLAGLPQSVSGTTINRLCGSGLDALGFAARAIKAGDGDLLIAGGVESM  120

Query  121  SRAPYVMGKSEGAFGRTQKIEDTTMGWRFINPKLKAMYGVDTMPQTAENVAEQFGIQRED  180
            SRAP+VMGK+  AF R  ++ DTT+GWRF+NP +   +G D+MP+TAENVAE   I RED
Sbjct  121  SRAPFVMGKAASAFSRQAEMFDTTIGWRFVNPLMAQQFGTDSMPETAENVAELLKISRED  180

Query  181  QDQFAYTSQQRTAAAQAKGYFAKEIVPVTIPQRKGEPVVIDTDEHPRASTTLEGLAKLKG  240
            QD FA  SQQRTA AQ+ G  A+EIVPV +  +KG    I  DEH R  TTLE L  LK 
Sbjct  181  QDSFALRSQQRTAKAQSSGILAEEIVPVVLKNKKGVVTEIQHDEHLRPETTLEQLRGLKA  240

Query  241  VVKPEGSVTAGNASGINDGAAAVLIASDEAVAQYQLKARAKIIASTTVGIEPRIMGFAPA  300
              +  G +TAGNASG+NDGAAA++IAS++  A   L  RA+I+A  T G+EPR+MG  P 
Sbjct  241  PFRANGVITAGNASGVNDGAAALIIASEQMAAAQGLTPRARIVAMATAGVEPRLMGLGPV  300

Query  301  PAIKKLLKQANLTLDQMDVIELNEAFAAQALACTRDLGLADDDARVNPNGGAIALGHPLG  360
            PA +++L++A L++  MDVIELNEAFAAQAL   R+LGL DD   VNPNGGAIALGHPLG
Sbjct  301  PATRRVLERAGLSIHDMDVIELNEAFAAQALGVLRELGLPDDAPHVNPNGGAIALGHPLG  360

Query  361  ASGARLVTTALNQLEQSGGKYALCSMCIGVGQGIALIIERV  401
             SGARL   A ++L +  G+YALC+MCIGVGQGIA+I+ERV
Sbjct  361  MSGARLALAASHELHRRNGRYALCTMCIGVGQGIAMILERV  401


>P0C7L3 Beta-ketoadipyl-CoA thiolase [Escherichia coli]
Length=401

 Score = 491 bits (1265),  Expect = 1e-177
 Identities = 246/401 (61%), Positives = 299/401 (75%), Gaps = 0/401 (0%)

Query  1    MKHAYIVDAIRTPFGRYAGGLAAVRADDLGAIPIAALIERNPSVNWAQVDDVIYGCANQA  60
            M+ A+I D IRTP GRY G L+ VRADDL AIP+  L+ RNP ++   +DDVI GCANQA
Sbjct  1    MREAFICDGIRTPIGRYGGALSGVRADDLAAIPLRELLVRNPRLDAECIDDVILGCANQA  60

Query  61   GEDNRNVGRMSALLAGLPVEVPATTVNRLCGSSLDAIAMAARAIKAGEAHLIIAGGVESM  120
            GEDNRNV RM+ LLAGLP  V  TT+NRLCGS LDA+  AARAIKAG+  L+IAGGVESM
Sbjct  61   GEDNRNVARMATLLAGLPQSVSGTTINRLCGSGLDALGFAARAIKAGDGDLLIAGGVESM  120

Query  121  SRAPYVMGKSEGAFGRTQKIEDTTMGWRFINPKLKAMYGVDTMPQTAENVAEQFGIQRED  180
            SRAP+VMGK+  AF R  ++ DTT+GWRF+NP +   +G D+MP+TAENVAE   I RED
Sbjct  121  SRAPFVMGKATSAFSRQAEMFDTTIGWRFVNPLMAQQFGTDSMPETAENVAELLKISRED  180

Query  181  QDQFAYTSQQRTAAAQAKGYFAKEIVPVTIPQRKGEPVVIDTDEHPRASTTLEGLAKLKG  240
            QD FA  SQQRTA AQ+ G  A+EIVPV +  +KG    I  DEH R  TTLE L  LK 
Sbjct  181  QDSFALRSQQRTAKAQSSGILAEEIVPVVLKNKKGVVTEIQHDEHLRPETTLEQLRGLKA  240

Query  241  VVKPEGSVTAGNASGINDGAAAVLIASDEAVAQYQLKARAKIIASTTVGIEPRIMGFAPA  300
              +  G +TAGNASG+NDGAAA++IAS++  A   L  RA+I+A  T G+EPR+MG  P 
Sbjct  241  PFRANGVITAGNASGVNDGAAALIIASEQMAAAQGLTPRARIVAMATAGVEPRLMGLGPV  300

Query  301  PAIKKLLKQANLTLDQMDVIELNEAFAAQALACTRDLGLADDDARVNPNGGAIALGHPLG  360
            PA +++L++A L++  MDVIELNEAFAAQAL   R+LGL DD   VNPNGGAIALGHPLG
Sbjct  301  PATRRVLERAGLSIHDMDVIELNEAFAAQALGVLRELGLPDDAPHVNPNGGAIALGHPLG  360

Query  361  ASGARLVTTALNQLEQSGGKYALCSMCIGVGQGIALIIERV  401
             SGARL   A ++L +  G+YALC+MCIGVGQGIA+I+ERV
Sbjct  361  MSGARLALAASHELHRRNGRYALCTMCIGVGQGIAMILERV  401


>Q9ZHI1 Acetyl-CoA acetyltransferase [Chromobacterium violaceum 
(strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 
9131 / NCTC 9757)]
Length=392

 Score = 335 bits (858),  Expect = 4e-116
 Identities = 190/397 (48%), Positives = 251/397 (63%), Gaps = 12/397 (3%)

Query  6    IVDAIRTPFGRYAGGLAAVRADDLGAIPIAALIERNPSVNWAQVDDVIYGCANQAGEDNR  65
            IV A RT  G + GGLA + A +LGA  I AL+E+   V    V +VI G    AG   +
Sbjct  5    IVAAQRTAIGSFGGGLAKIPAPELGATVIKALLEKT-GVKPEDVSEVILGQVLTAGS-GQ  62

Query  66   NVGRMSALLAGLPVEVPATTVNRLCGSSLDAIAMAARAIKAGEAHLIIAGGVESMSRAPY  125
            N  R + + AGLPV  PATT+N +CGS L A+ +AA+AI AG+A ++IAGG ESMS +P+
Sbjct  63   NPARQALIKAGLPVTTPATTLNVVCGSGLRAVHLAAQAILAGDADIVIAGGQESMSLSPH  122

Query  126  VMGKSEGAF--GRTQKIEDTTMGWRFINPKLKAMYGVDTMPQTAENVAEQFGIQREDQDQ  183
            ++  S   F  G  Q ++        +N  L   Y    M  TAENVA ++GI RE+QD 
Sbjct  123  ILPGSRDGFRMGNAQLVDT------MVNDGLTDAYNAYHMGITAENVAAKYGIGREEQDA  176

Query  184  FAYTSQQRTAAAQAKGYFAKEIVPVTIPQRKGEPVVIDTDEHPRASTTLEGLAKLKGVVK  243
            F+  SQQR AAAQ  G F  EIVPV +PQRKG+P+  D DE  +   + +GLAKL+   K
Sbjct  177  FSLQSQQRAAAAQKAGKFRDEIVPVLVPQRKGDPLAFDADEFIKHDASADGLAKLRPAFK  236

Query  244  PEGSVTAGNASGINDGAAAVLIASDEAVAQYQLKARAKIIASTTVGIEPRIMGFAPAPAI  303
             +G+VTAGNASGINDGAAAVL+ S +   Q  LK  A I      G EP IMG  P  A 
Sbjct  237  KDGTVTAGNASGINDGAAAVLLMSTQKADQLGLKPLAIIKGYALTGCEPEIMGIGPVSAT  296

Query  304  KKLLKQANLTLDQMDVIELNEAFAAQALACTRDLGLADDDARVNPNGGAIALGHPLGASG  363
            +K L +A  T++ +D++E NEAFAAQAL   ++LG   D  +VN NGGAIALGHP+GASG
Sbjct  297  RKALSKAGWTVEDLDLVEANEAFAAQALGVAKELGWGSD--KVNVNGGAIALGHPIGASG  354

Query  364  ARLVTTALNQLEQSGGKYALCSMCIGVGQGIALIIER  400
             R++ T L+++++ G K  L ++CIG G G+AL +ER
Sbjct  355  CRVLVTLLHEMQRRGAKKGLATLCIGGGMGVALAVER  391


>Q9I2A8 Acetyl-CoA acetyltransferase [Pseudomonas aeruginosa (strain 
ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 
12228 / 1C / PRS 101 / PAO1)]
Length=393

 Score = 333 bits (854),  Expect = 2e-115
 Identities = 192/401 (48%), Positives = 257/401 (64%), Gaps = 10/401 (2%)

Query  1    MKHAYIVDAIRTPFGRYAGGLAAVRADDLGAIPIAALIERNPSVNWAQVDDVIYGCANQA  60
            M+   IV A RT  G + G LA + A +LGA  I  L+E+   ++  QVD+VI G    A
Sbjct  1    MQDVVIVAATRTAVGSFQGSLAGIPAPELGAAVIRRLLEQT-GLDAGQVDEVILGQVLTA  59

Query  61   GEDNRNVGRMSALLAGLPVEVPATTVNRLCGSSLDAIAMAARAIKAGEAHLIIAGGVESM  120
            G   +N  R +A+ AGLPV VPA T+N++CGS L A+ + A+AI+ G+A +I+AGG E+M
Sbjct  60   GS-GQNPARQAAIKAGLPVGVPAMTLNKVCGSGLKALHLGAQAIRCGDAEVIVAGGQENM  118

Query  121  SRAPYVM-GKSEGAFGRTQKIEDTTMGWRFINPKLKAMYGVDTMPQTAENVAEQFGIQRE  179
            S APYVM G   G      K+ D+      I   L   +    M  TAEN+AE++G+ RE
Sbjct  119  SLAPYVMPGARTGLRMGHAKLVDS-----MIEDGLWDAFNDYHMGITAENLAEKYGLTRE  173

Query  180  DQDQFAYTSQQRTAAAQAKGYFAKEIVPVTIPQRKGEPVVIDTDEHPRASTTLEGLAKLK  239
            +QD FA  SQQ+  AA   G F  EI P+ +PQRKGEP+  DTDE PRA TT+E LAKLK
Sbjct  174  EQDAFAAASQQKAIAAIEGGRFRDEITPIQVPQRKGEPLGFDTDEQPRAGTTVEALAKLK  233

Query  240  GVVKPEGSVTAGNASGINDGAAAVLIASDEAVAQYQLKARAKIIASTTVGIEPRIMGFAP  299
               + +GSVTAGNAS +NDGAAAVL+ S        L   A+I +  + G++P IMG  P
Sbjct  234  PAFRKDGSVTAGNASSLNDGAAAVLLMSAAKAKALGLPVLARIASYASAGVDPAIMGIGP  293

Query  300  APAIKKLLKQANLTLDQMDVIELNEAFAAQALACTRDLGLADDDARVNPNGGAIALGHPL  359
              A ++ L +A  +L+Q+D+IE NEAFAAQ+LA  R+LG   D ARVN NGGAIALGHP+
Sbjct  294  VSATRRALDKAGWSLEQLDLIEANEAFAAQSLAVGRELGW--DAARVNVNGGAIALGHPI  351

Query  360  GASGARLVTTALNQLEQSGGKYALCSMCIGVGQGIALIIER  400
            GASG R++ T L+++ +   K  L ++CIG GQG+AL + R
Sbjct  352  GASGCRVLVTLLHEMIRRDAKKGLATLCIGGGQGVALTLAR  392


>Q0AVM3 Acetyl-CoA acetyltransferase [Syntrophomonas wolfei subsp. 
wolfei (strain DSM 2245B / Goettingen)]
Length=396

 Score = 330 bits (847),  Expect = 2e-114
 Identities = 181/400 (45%), Positives = 255/400 (64%), Gaps = 10/400 (3%)

Query  2    KHAYIVDAIRTPFGRYAGGLAAVRADDLGAIPIAALIERNPSVNWAQVDDVIYGCANQAG  61
            +   +V A RTP G + G L  V +  LGAI +   I+R   +   Q+D+VI+GC  QAG
Sbjct  3    REVVLVGACRTPVGTFGGTLKDVGSAQLGAIVMGEAIKR-AGIKAEQIDEVIFGCVLQAG  61

Query  62   EDNRNVGRMSALLAGLPVEVPATTVNRLCGSSLDAIAMAARAIKAGEAHLIIAGGVESMS  121
               +NV R   + AG+P EV A T+N++CGS L A+++AA+ IKAG+A +I+AGG E+M 
Sbjct  62   L-GQNVARQCMINAGIPKEVTAFTINKVCGSGLRAVSLAAQVIKAGDADIIMAGGTENMD  120

Query  122  RAPYVMGKSEGAFGRTQKIEDTT--MGWRFINPKLKAMYGVDTMPQTAENVAEQFGIQRE  179
            +AP+++  +   +  +    D    M W  +       +    M  TAEN+ + +GI RE
Sbjct  121  KAPFILPNARWGYRMSMPKGDLIDEMVWGGLTDVFNGYH----MGITAENINDMYGITRE  176

Query  180  DQDQFAYTSQQRTAAAQAKGYFAKEIVPVTIPQRKGEPVVIDTDEHPRASTTLEGLAKLK  239
            +QD F + SQ   A A   G F  EIVPV I  +KG+ +V DTDEHPR ST  E +AKL 
Sbjct  177  EQDAFGFRSQTLAAQAIESGRFKDEIVPVVIKGKKGD-IVFDTDEHPRKSTP-EAMAKLA  234

Query  240  GVVKPEGSVTAGNASGINDGAAAVLIASDEAVAQYQLKARAKIIASTTVGIEPRIMGFAP  299
               K  GSVTAGNASGIND AAAV++ S E   +  +K  AK+++  + G++P +MG  P
Sbjct  235  PAFKKGGSVTAGNASGINDAAAAVIVMSKEKADELGIKPMAKVVSYASGGVDPSVMGLGP  294

Query  300  APAIKKLLKQANLTLDQMDVIELNEAFAAQALACTRDLGLADDDARVNPNGGAIALGHPL  359
             PA +K L++A LT+D +D+IE NEAFAAQ++A  RDLG AD   +VN NGGAIA+GHP+
Sbjct  295  IPASRKALEKAGLTIDDIDLIEANEAFAAQSIAVARDLGWADKMEKVNVNGGAIAIGHPI  354

Query  360  GASGARLVTTALNQLEQSGGKYALCSMCIGVGQGIALIIE  399
            G+SGAR++ T L ++++ G K  L ++CIG G G ALI+E
Sbjct  355  GSSGARILVTLLYEMQKRGSKKGLATLCIGGGMGTALIVE  394


>P45369 Acetyl-CoA acetyltransferase [Allochromatium vinosum (strain 
ATCC 17899 / DSM 180 / NBRC 103801 / NCIMB 10441 / D)]
Length=394

 Score = 324 bits (830),  Expect = 8e-112
 Identities = 178/396 (45%), Positives = 254/396 (64%), Gaps = 8/396 (2%)

Query  6    IVDAIRTPFGRYAGGLAAVRADDLGAIPIAALIERNPSVNWAQVDDVIYGCANQAGEDNR  65
            IVDA R+  G ++G L+++ A ++G   +  L+ R   +   Q+D+VI G    AG   +
Sbjct  7    IVDAGRSAIGTFSGSLSSLSATEIGTAVLKGLLART-GLAPEQIDEVILGQVLTAGV-GQ  64

Query  66   NVGRMSALLAGLPVEVPATTVNRLCGSSLDAIAMAARAIKAGEAHLIIAGGVESMSRAPY  125
            N  R + L AGLP  VPA T+N++CGS L A+ +A +AI  G+A ++IAGG ESMS++ +
Sbjct  65   NPARQTTLKAGLPHSVPAMTINKVCGSGLKAVHLAMQAIACGDADIVIAGGQESMSQSSH  124

Query  126  VMGKSEGAFGRTQKIEDTTMGWRFINPKLKAMYGVDTMPQTAENVAEQFGIQREDQDQFA  185
            V+ +S       Q++ D +M    I   L   +    M  TAEN+A+++G  RE QD FA
Sbjct  125  VLPRSRDG----QRMGDWSMKDTMIVDGLWDAFNNYHMGTTAENIAQKYGFTREQQDAFA  180

Query  186  YTSQQRTAAAQAKGYFAKEIVPVTIPQRKGEPVVIDTDEHPRASTTLEGLAKLKGVVKPE  245
              SQQ+T AAQ  G F  EI+P+ IPQRKG+P V D DE PR  TT E L KL+     +
Sbjct  181  AASQQKTEAAQKAGRFQDEIIPIEIPQRKGDPKVFDADEFPRHGTTAESLGKLRPAFSRD  240

Query  246  GSVTAGNASGINDGAAAVLIASDEAVAQYQLKARAKIIASTTVGIEPRIMGFAPAPAIKK  305
            GSVTAGNASGINDGAA V++  +    +  LK  A+++A  + G++P IMG  P PA  K
Sbjct  241  GSVTAGNASGINDGAAMVVVMKESKAKELGLKPMARLVAFASAGVDPAIMGTGPIPASTK  300

Query  306  LLKQANLTLDQMDVIELNEAFAAQALACTRDLGLADDDARVNPNGGAIALGHPLGASGAR  365
             L++A  T   +D+IE NEAFAAQA++  +D+G   D ++VN NGGAIA+GHP+GASGAR
Sbjct  301  CLEKAGWTPADLDLIEANEAFAAQAMSVNQDMGW--DLSKVNVNGGAIAIGHPIGASGAR  358

Query  366  LVTTALNQLEQSGGKYALCSMCIGVGQGIALIIERV  401
            ++ T L ++++   K  L ++CIG GQG+AL +ER+
Sbjct  359  VLVTLLYEMQKRDAKKGLATLCIGGGQGVALAVERM  394


>P45359 Acetyl-CoA acetyltransferase [Clostridium acetobutylicum 
(strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)]
Length=392

 Score = 323 bits (829),  Expect = 1e-111
 Identities = 183/402 (46%), Positives = 259/402 (64%), Gaps = 13/402 (3%)

Query  1    MKHAYIVDAIRTPFGRYAGGLAAVRADDLGAIPIAALIERNPSVNWAQVDDVIYGCANQA  60
            MK   I  A+RT  G Y   L  V A DLGA  I   +++   +    V++VI G   QA
Sbjct  1    MKEVVIASAVRTAIGSYGKSLKDVPAVDLGATAIKEAVKK-AGIKPEDVNEVILGNVLQA  59

Query  61   GEDNRNVGRMSALLAGLPVEVPATTVNRLCGSSLDAIAMAARAIKAGEAHLIIAGGVESM  120
            G   +N  R ++  AGLPVE+PA T+N++CGS L  +++AA+ IKAG+A +IIAGG+E+M
Sbjct  60   GL-GQNPARQASFKAGLPVEIPAMTINKVCGSGLRTVSLAAQIIKAGDADVIIAGGMENM  118

Query  121  SRAPYVMGKSEGAF--GRTQKIEDTTMGWRFINPKLKAMYGVDTMPQTAENVAEQFGIQR  178
            SRAPY+   +   +  G  + +++       I   L   +    M  TAEN+AE++ I R
Sbjct  119  SRAPYLANNARWGYRMGNAKFVDE------MITDGLWDAFNDYHMGITAENIAERWNISR  172

Query  179  EDQDQFAYTSQQRTAAAQAKGYFAKEIVPVTIPQRKGEPVVIDTDEHPRASTTLEGLAKL  238
            E+QD+FA  SQ++   A   G F  EIVPV I  RKGE VV DTDEHPR  +T+EGLAKL
Sbjct  173  EEQDEFALASQKKAEEAIKSGQFKDEIVPVVIKGRKGETVV-DTDEHPRFGSTIEGLAKL  231

Query  239  KGVVKPEGSVTAGNASGINDGAAAVLIASDEAVAQYQLKARAKIIASTTVGIEPRIMGFA  298
            K   K +G+VTAGNASG+ND AA ++I S E   +  +K  AKI++  + G++P IMG+ 
Sbjct  232  KPAFKKDGTVTAGNASGLNDCAAVLVIMSAEKAKELGVKPLAKIVSYGSAGVDPAIMGYG  291

Query  299  PAPAIKKLLKQANLTLDQMDVIELNEAFAAQALACTRDLGLADDDARVNPNGGAIALGHP  358
            P  A K  +++A  T+D++D+IE NEAFAAQ+LA  +DL    D  +VN NGGAIALGHP
Sbjct  292  PFYATKAAIEKAGWTVDELDLIESNEAFAAQSLAVAKDLKF--DMNKVNVNGGAIALGHP  349

Query  359  LGASGARLVTTALNQLEQSGGKYALCSMCIGVGQGIALIIER  400
            +GASGAR++ T ++ +++   K  L ++CIG GQG A+++E+
Sbjct  350  IGASGARILVTLVHAMQKRDAKKGLATLCIGGGQGTAILLEK  391


>P14611 Acetyl-CoA acetyltransferase [Cupriavidus necator (strain 
ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / 
Stanier 337)]
Length=393

 Score = 323 bits (829),  Expect = 1e-111
 Identities = 182/400 (46%), Positives = 250/400 (63%), Gaps = 8/400 (2%)

Query  1    MKHAYIVDAIRTPFGRYAGGLAAVRADDLGAIPIAALIERNPSVNWAQVDDVIYGCANQA  60
            M    IV A RT  G++ G LA + A +LGA+ I A +ER   V   QV +VI G    A
Sbjct  1    MTDVVIVSAARTAVGKFGGSLAKIPAPELGAVVIKAALER-AGVKPEQVSEVIMGQVLTA  59

Query  61   GEDNRNVGRMSALLAGLPVEVPATTVNRLCGSSLDAIAMAARAIKAGEAHLIIAGGVESM  120
            G   +N  R +A+ AGLP  VPA T+N++CGS L A+ +AA AI AG+A +++AGG E+M
Sbjct  60   GS-GQNPARQAAIKAGLPAMVPAMTINKVCGSGLKAVMLAANAIMAGDAEIVVAGGQENM  118

Query  121  SRAPYVMGKSEGAFGRTQKIEDTTMGWRFINPKLKAMYGVDTMPQTAENVAEQFGIQRED  180
            S AP+V+  S   F    ++ D  +    I   L  +Y    M  TAENVA+++GI RE 
Sbjct  119  SAAPHVLPGSRDGF----RMGDAKLVDTMIVDGLWDVYNQYHMGITAENVAKEYGITREA  174

Query  181  QDQFAYTSQQRTAAAQAKGYFAKEIVPVTIPQRKGEPVVIDTDEHPRASTTLEGLAKLKG  240
            QD+FA  SQ +  AAQ  G F +EIVPV IPQRKG+PV   TDE  R   TL+ ++ LK 
Sbjct  175  QDEFAVGSQNKAEAAQKAGKFDEEIVPVLIPQRKGDPVAFKTDEFVRQGATLDSMSGLKP  234

Query  241  VVKPEGSVTAGNASGINDGAAAVLIASDEAVAQYQLKARAKIIASTTVGIEPRIMGFAPA  300
                 G+VTA NASG+NDGAAAV++ S     +  L   A I +    G++P++MG  P 
Sbjct  235  AFDKAGTVTAANASGLNDGAAAVVVMSAAKAKELGLTPLATIKSYANAGVDPKVMGMGPV  294

Query  301  PAIKKLLKQANLTLDQMDVIELNEAFAAQALACTRDLGLADDDARVNPNGGAIALGHPLG  360
            PA K+ L +A  T   +D++E+NEAFAAQALA  + +G   D ++VN NGGAIA+GHP+G
Sbjct  295  PASKRALSRAEWTPQDLDLMEINEAFAAQALAVHQQMGW--DTSKVNVNGGAIAIGHPIG  352

Query  361  ASGARLVTTALNQLEQSGGKYALCSMCIGVGQGIALIIER  400
            ASG R++ T L+++++   K  L S+CIG G G+AL +ER
Sbjct  353  ASGCRILVTLLHEMKRRDAKKGLASLCIGGGMGVALAVER  392



Lambda      K        H        a         alpha
   0.318    0.133    0.381    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 1607868


  Database: e0640296e72129ef29a65fd580adf489.SwissProt.fasta
    Posted date:  May 19, 2024  5:17 AM
  Number of letters in database: 5,166
  Number of sequences in database:  13



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40