BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 02e97303b9208ee9fa3d9ebf5301b9bd.SwissProt.fasta
12 sequences; 4,894 total letters
Query= ACIAD1723
Length=380
Score E
Sequences producing significant alignments: (Bits) Value
P79274 Long-chain specific acyl-CoA dehydrogenase, mitochondrial ... 309 6e-106
P15650 Long-chain specific acyl-CoA dehydrogenase, mitochondrial ... 305 2e-104
Q60HI0 Long-chain specific acyl-CoA dehydrogenase, mitochondrial ... 303 1e-103
P51174 Long-chain specific acyl-CoA dehydrogenase, mitochondrial ... 302 3e-103
P28330 Long-chain specific acyl-CoA dehydrogenase, mitochondrial ... 296 8e-101
P45857 Acyl-CoA dehydrogenase [Bacillus subtilis (strain 168)] 227 2e-74
P52042 Acyl-CoA dehydrogenase, short-chain specific [Clostridium ... 224 2e-73
P45867 Acyl-CoA dehydrogenase [Bacillus subtilis (strain 168)] 221 2e-72
Q9FS87 Isovaleryl-CoA dehydrogenase, mitochondrial [Solanum tuber... 220 1e-71
G3KIM8 Acryloyl-CoA reductase (NADH) [Anaerotignum propionicum] 218 4e-71
P12007 Isovaleryl-CoA dehydrogenase, mitochondrial [Rattus norveg... 216 8e-70
J7TF92 3-(aryl)acrylate reductase [Clostridium sporogenes (strain... 214 9e-70
>P79274 Long-chain specific acyl-CoA dehydrogenase, mitochondrial
[Sus scrofa]
Length=430
Score = 309 bits (792), Expect = 6e-106
Identities = 155/375 (41%), Positives = 246/375 (66%), Gaps = 4/375 (1%)
Query 5 TDFELFRDTYKRFLNDHVAPYYEQWEHDGLIPRHIWNLLGENGFLCVDVPEEYGGYGAPV 64
++ ++FR++ ++F + V P++ +WE G + R +W G+ G L +++ E +GG G +
Sbjct 55 SEHDIFRESVRKFFQEEVIPHHAEWEKAGEVSRELWEKAGKQGLLGINIAERHGGIGGDL 114
Query 65 HYSLMLVQETARAGFGSLAVAIGGQNELVSPYIQNMGSEAQKKYWLPKMVSGEVVTAIAM 124
+ + ++ +E A + ++ +++V PYI N GSE Q K+++P+M +G+ + AIAM
Sbjct 115 YSAAIVWEEQAYSNCTGPGFSL--HSDIVMPYIANYGSEEQIKHFIPQMTAGKCIGAIAM 172
Query 125 TEANAGSDLQAIRTQAILKNEHYVIDGSKTFISNGLHADLIVLVAKTDPQAR--AKGISL 182
TE AGSDLQ +RT A ++++GSK FI+NG +D++++VA T+ +AR A GISL
Sbjct 173 TEPGAGSDLQGVRTNAKKDGSDWILNGSKVFITNGWLSDVVIVVAVTNREARSPAHGISL 232
Query 183 FLVDAQLEGVEKGRSLKKIGLHAQDTAELFFDGVHVPVTQRLGQEGQGFAYLMQELPRER 242
FLV+ ++G KGR L KIGL AQDTAELFF+ V +P + LG+E +GF YLMQELP+ER
Sbjct 233 FLVENGMKGFVKGRKLHKIGLKAQDTAELFFEDVRLPASALLGEENKGFYYLMQELPQER 292
Query 243 LSIAMMGMGSIWGAIDLTTSYVRERKAFGQTLAQLQNTRFVIANAQIKAKAAQAFIHECA 302
L IA + + + + T +YV++RKAFG+T+A +Q + +A + +AF+ C
Sbjct 293 LLIAELAVSASEFMFEETRNYVKQRKAFGKTVAHIQTVQHKLAELKTHICVTRAFVDSCL 352
Query 303 QMYHQGALTVGHVAALKCFITDTQCDVIDQLLQLFGGYGYMQEYPISRFFVDSRVQKIYG 362
Q++ L + K + ++ Q V +QL GG+GYM EYPI+R +VD+RVQ IYG
Sbjct 353 QLHETKRLESAAASMAKYWASELQNSVAYDCVQLHGGWGYMWEYPIARAYVDARVQPIYG 412
Query 363 GTNEIMKEIVARDVL 377
GTNEIMKE++AR+++
Sbjct 413 GTNEIMKELIAREIV 427
>P15650 Long-chain specific acyl-CoA dehydrogenase, mitochondrial
[Rattus norvegicus]
Length=430
Score = 305 bits (782), Expect = 2e-104
Identities = 153/375 (41%), Positives = 245/375 (65%), Gaps = 4/375 (1%)
Query 5 TDFELFRDTYKRFLNDHVAPYYEQWEHDGLIPRHIWNLLGENGFLCVDVPEEYGGYGAPV 64
++ ++FR++ ++F + V PY+E+WE G + R +W G+ G L +++ E++GG G +
Sbjct 55 SEHDIFRESVRKFFQEEVIPYHEEWEKAGEVSRELWEKAGKQGLLGINIAEKHGGIGGDL 114
Query 65 HYSLMLVQETARAGFGSLAVAIGGQNELVSPYIQNMGSEAQKKYWLPKMVSGEVVTAIAM 124
+ + +E A + ++ +++V PYI N G++ Q + ++P+M +G+ + AIAM
Sbjct 115 LSTAVTWEEQAYSNCTGPGFSL--HSDIVMPYIANYGTKEQIEQFIPQMTAGKCIGAIAM 172
Query 125 TEANAGSDLQAIRTQAILKNEHYVIDGSKTFISNGLHADLIVLVAKTDPQAR--AKGISL 182
TE AGSDLQ +RT A ++++GSK FI+NG +DL+++VA T+ +AR A GISL
Sbjct 173 TEPGAGSDLQGVRTNAKRSGSDWILNGSKVFITNGWLSDLVIVVAVTNREARSPAHGISL 232
Query 183 FLVDAQLEGVEKGRSLKKIGLHAQDTAELFFDGVHVPVTQRLGQEGQGFAYLMQELPRER 242
FLV+ ++G KG+ L K+G+ AQDTAELFF+ V +P + LG+E +GF YLMQELP+ER
Sbjct 233 FLVENGMKGFIKGKKLHKMGMKAQDTAELFFEDVRLPASALLGEENKGFYYLMQELPQER 292
Query 243 LSIAMMGMGSIWGAIDLTTSYVRERKAFGQTLAQLQNTRFVIANAQIKAKAAQAFIHECA 302
L IA + + + + T +YVR+RKAFG+T+A +Q + +A + +AF+ C
Sbjct 293 LLIADLAISACEFMFEETRNYVRQRKAFGKTVAHIQTVQHKLAELKTNICVTRAFVDSCL 352
Query 303 QMYHQGALTVGHVAALKCFITDTQCDVIDQLLQLFGGYGYMQEYPISRFFVDSRVQKIYG 362
Q++ L + K + ++ Q V Q +QL GG+GYM EYPI++ +VD+RVQ IYG
Sbjct 353 QLHETKRLDSASASMAKYWASELQNTVAYQCVQLHGGWGYMWEYPIAKAYVDARVQPIYG 412
Query 363 GTNEIMKEIVARDVL 377
GTNEIMKE++AR ++
Sbjct 413 GTNEIMKELIARQIV 427
>Q60HI0 Long-chain specific acyl-CoA dehydrogenase, mitochondrial
[Macaca fascicularis]
Length=430
Score = 303 bits (776), Expect = 1e-103
Identities = 154/375 (41%), Positives = 242/375 (65%), Gaps = 4/375 (1%)
Query 5 TDFELFRDTYKRFLNDHVAPYYEQWEHDGLIPRHIWNLLGENGFLCVDVPEEYGGYGAPV 64
++ ++FR + ++F + V P++ +WE G + R +W G+ G L V++ E GG G +
Sbjct 55 SEHDIFRKSIRKFFQEEVIPHHSEWEKAGEVSREVWEKAGKQGLLGVNIAEHLGGIGGDL 114
Query 65 HYSLMLVQETARAGFGSLAVAIGGQNELVSPYIQNMGSEAQKKYWLPKMVSGEVVTAIAM 124
+Y+ ++ +E A + ++ + +V YI N GSE Q K+++P+M +G+ + AIAM
Sbjct 115 YYAAVVWEEQAYSNCSGPGFSV--HSGIVMSYITNYGSEEQIKHFIPQMTAGKCIGAIAM 172
Query 125 TEANAGSDLQAIRTQAILKNEHYVIDGSKTFISNGLHADLIVLVAKTDPQAR--AKGISL 182
TE AGSDLQ I+T A ++++GSK FISNG +D++++VA T+ +A A+GISL
Sbjct 173 TELGAGSDLQGIKTNAKKDGSDWILNGSKVFISNGWLSDVVIVVAVTNHEAPSPARGISL 232
Query 183 FLVDAQLEGVEKGRSLKKIGLHAQDTAELFFDGVHVPVTQRLGQEGQGFAYLMQELPRER 242
FLV+ ++G KGR L K+GL AQDTAELFF+ V +P + LG+E +GF Y+M+ELP+ER
Sbjct 233 FLVENGMKGFIKGRKLHKMGLKAQDTAELFFEDVRLPASALLGEENKGFYYIMKELPQER 292
Query 243 LSIAMMGMGSIWGAIDLTTSYVRERKAFGQTLAQLQNTRFVIANAQIKAKAAQAFIHECA 302
L IA M + + + T +YV++RKAFG+T+A LQ + +A + +AF+ C
Sbjct 293 LLIADMAVSASEFMFEETRNYVKQRKAFGKTVAHLQTVQHKLAELKTHICVTRAFVDNCL 352
Query 303 QMYHQGALTVGHVAALKCFITDTQCDVIDQLLQLFGGYGYMQEYPISRFFVDSRVQKIYG 362
Q++ L K + ++ Q V +QL GG+GYM EYPI++ +VD+RVQ IYG
Sbjct 353 QLHEAKRLDSATACMAKYWASELQNSVAYDCVQLHGGWGYMWEYPIAKAYVDARVQPIYG 412
Query 363 GTNEIMKEIVARDVL 377
GTNEIMKE++AR+++
Sbjct 413 GTNEIMKELIAREIV 427
>P51174 Long-chain specific acyl-CoA dehydrogenase, mitochondrial
[Mus musculus]
Length=430
Score = 302 bits (774), Expect = 3e-103
Identities = 151/375 (40%), Positives = 244/375 (65%), Gaps = 4/375 (1%)
Query 5 TDFELFRDTYKRFLNDHVAPYYEQWEHDGLIPRHIWNLLGENGFLCVDVPEEYGGYGAPV 64
++ ++FR++ ++F + V P++ +WE G + R +W G+ G L +++ E++GG G +
Sbjct 55 SEHDIFRESVRKFFQEEVIPHHTEWEKAGEVSREVWEKAGKQGLLGINIAEKHGGIGGDL 114
Query 65 HYSLMLVQETARAGFGSLAVAIGGQNELVSPYIQNMGSEAQKKYWLPKMVSGEVVTAIAM 124
+ + +E A + ++ +++V PYI N G++ Q + ++P+M +G+ + AIAM
Sbjct 115 LSTAVTWEEQAYSNCTGPGFSL--HSDIVMPYIANYGTKEQIEKFIPQMTAGKCIGAIAM 172
Query 125 TEANAGSDLQAIRTQAILKNEHYVIDGSKTFISNGLHADLIVLVAKTDPQAR--AKGISL 182
TE AGSDLQ +RT A ++++GSK FI+NG +DL+++VA T+ +AR A GISL
Sbjct 173 TEPGAGSDLQGVRTNAKRSGSDWILNGSKVFITNGWLSDLVIVVAVTNREARSPAHGISL 232
Query 183 FLVDAQLEGVEKGRSLKKIGLHAQDTAELFFDGVHVPVTQRLGQEGQGFAYLMQELPRER 242
FLV+ ++G KGR L K+G+ AQDTAELFF+ V +P LG+E +GF YLMQELP+ER
Sbjct 233 FLVENGMKGFIKGRKLHKMGMKAQDTAELFFEDVRLPANALLGEENKGFYYLMQELPQER 292
Query 243 LSIAMMGMGSIWGAIDLTTSYVRERKAFGQTLAQLQNTRFVIANAQIKAKAAQAFIHECA 302
L IA + + + + T +YV++RKAFG+T+A +Q + +A + +AF+ C
Sbjct 293 LLIAELAISACEFMFEETRNYVKQRKAFGKTVAHIQTVQHKLAELKTHICVTRAFVDSCL 352
Query 303 QMYHQGALTVGHVAALKCFITDTQCDVIDQLLQLFGGYGYMQEYPISRFFVDSRVQKIYG 362
Q++ L G + K + ++ Q V + +QL GG+GYM EYPI++ +VD+RVQ IYG
Sbjct 353 QLHETKRLDSGSASMAKYWASELQNSVAYECVQLHGGWGYMWEYPIAKAYVDARVQPIYG 412
Query 363 GTNEIMKEIVARDVL 377
GTNEIMKE++AR ++
Sbjct 413 GTNEIMKELIARQIV 427
>P28330 Long-chain specific acyl-CoA dehydrogenase, mitochondrial
[Homo sapiens]
Length=430
Score = 296 bits (758), Expect = 8e-101
Identities = 152/374 (41%), Positives = 239/374 (64%), Gaps = 4/374 (1%)
Query 6 DFELFRDTYKRFLNDHVAPYYEQWEHDGLIPRHIWNLLGENGFLCVDVPEEYGGYGAPVH 65
+ ++FR + ++F + V P++ +WE G + R +W G+ G L V++ E GG G ++
Sbjct 56 EHDIFRKSVRKFFQEEVIPHHSEWEKAGEVSREVWEKAGKQGLLGVNIAEHLGGIGGDLY 115
Query 66 YSLMLVQETARAGFGSLAVAIGGQNELVSPYIQNMGSEAQKKYWLPKMVSGEVVTAIAMT 125
+ ++ +E A + +I + +V YI N GSE Q K+++P+M +G+ + AIAMT
Sbjct 116 SAAIVWEEQAYSNCSGPGFSI--HSGIVMSYITNHGSEEQIKHFIPQMTAGKCIGAIAMT 173
Query 126 EANAGSDLQAIRTQAILKNEHYVIDGSKTFISNGLHADLIVLVAKTDPQAR--AKGISLF 183
E AGSDLQ I+T A ++++GSK FISNG +D++++VA T+ +A A GISLF
Sbjct 174 EPGAGSDLQGIKTNAKKDGSDWILNGSKVFISNGSLSDVVIVVAVTNHEAPSPAHGISLF 233
Query 184 LVDAQLEGVEKGRSLKKIGLHAQDTAELFFDGVHVPVTQRLGQEGQGFAYLMQELPRERL 243
LV+ ++G KGR L K+GL AQDTAELFF+ + +P + LG+E +GF Y+M+ELP+ERL
Sbjct 234 LVENGMKGFIKGRKLHKMGLKAQDTAELFFEDIRLPASALLGEENKGFYYIMKELPQERL 293
Query 244 SIAMMGMGSIWGAIDLTTSYVRERKAFGQTLAQLQNTRFVIANAQIKAKAAQAFIHECAQ 303
IA + + + + T +YV++RKAFG+T+A LQ + +A + +AF+ C Q
Sbjct 294 LIADVAISASEFMFEETRNYVKQRKAFGKTVAHLQTVQHKLAELKTHICVTRAFVDNCLQ 353
Query 304 MYHQGALTVGHVAALKCFITDTQCDVIDQLLQLFGGYGYMQEYPISRFFVDSRVQKIYGG 363
++ L K + ++ Q V +QL GG+GYM EYPI++ +VD+RVQ IYGG
Sbjct 354 LHEAKRLDSATACMAKYWASELQNSVAYDCVQLHGGWGYMWEYPIAKAYVDARVQPIYGG 413
Query 364 TNEIMKEIVARDVL 377
TNEIMKE++AR+++
Sbjct 414 TNEIMKELIAREIV 427
>P45857 Acyl-CoA dehydrogenase [Bacillus subtilis (strain 168)]
Length=379
Score = 227 bits (578), Expect = 2e-74
Identities = 123/370 (33%), Positives = 202/370 (55%), Gaps = 1/370 (0%)
Query 9 LFRDTYKRFLNDHVAPYYEQWEHDGLIPRHIWNLLGENGFLCVDVPEEYGGYGAPVHYSL 68
+ R + F +AP E E P + +G++G + + VPE+YGG GA V +
Sbjct 9 MMRKMVRDFARKEIAPAAEIMEKTDEFPFQLIKKMGKHGLMGIPVPEQYGGAGADVVSYI 68
Query 69 MLVQETARAGFGSLAVAIGGQNELVSPYIQNMGSEAQKKYWLPKMVSGEVVTAIAMTEAN 128
+ + E +R ++ V + + + I G+E QK ++P + SG+ + A A+TE +
Sbjct 69 LAIHEISRIS-AAVGVILSVHTSVGTNPILYFGNEEQKMKYIPNLASGDHLGAFALTEPH 127
Query 129 AGSDLQAIRTQAILKNEHYVIDGSKTFISNGLHADLIVLVAKTDPQARAKGISLFLVDAQ 188
+GSD ++RT AI KN Y+++GSK FI+NG AD+ + A T P GIS F+V+
Sbjct 128 SGSDAGSLRTTAIKKNGKYLLNGSKIFITNGGAADIYITFALTAPDQGRHGISAFIVEKN 187
Query 189 LEGVEKGRSLKKIGLHAQDTAELFFDGVHVPVTQRLGQEGQGFAYLMQELPRERLSIAMM 248
G G+ +K+GL+ +T EL FD VP LG+EG GF M L R+ IA
Sbjct 188 TPGFTVGKKERKLGLYGSNTTELIFDNAEVPEANLLGKEGDGFHIAMANLNVGRIGIAAQ 247
Query 249 GMGSIWGAIDLTTSYVRERKAFGQTLAQLQNTRFVIANAQIKAKAAQAFIHECAQMYHQG 308
+G A++ Y ++R FG+ +A Q F +A+ +A+AA+ ++ A ++++G
Sbjct 248 ALGIAEAALEHAVDYAKQRVQFGRPIAANQGISFKLADMATRAEAARHLVYHAADLHNRG 307
Query 309 ALTVGHVAALKCFITDTQCDVIDQLLQLFGGYGYMQEYPISRFFVDSRVQKIYGGTNEIM 368
+ K F +D +Q++GGYGYM++YP+ R D++V +IY GTNEI
Sbjct 308 LNCGKEASMAKQFASDAAVKAALDAVQIYGGYGYMKDYPVERLLRDAKVTQIYEGTNEIQ 367
Query 369 KEIVARDVLG 378
+ I+++ +LG
Sbjct 368 RLIISKYLLG 377
>P52042 Acyl-CoA dehydrogenase, short-chain specific [Clostridium
acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG
5710 / VKM B-1787)]
Length=379
Score = 224 bits (570), Expect = 2e-73
Identities = 120/366 (33%), Positives = 201/366 (55%), Gaps = 1/366 (0%)
Query 8 ELFRDTYKRFLNDHVAPYYEQWEHDGLIPRHIWNLLGENGFLCVDVPEEYGGYGAPVHYS 67
EL R + F + V P + + P +G+ G + + +EYGG G V
Sbjct 10 ELVRQMVREFAENEVKPIAAEIDETERFPMENVKKMGQYGMMGIPFSKEYGGAGGDVLSY 69
Query 68 LMLVQETARAGFGSLAVAIGGQNELVSPYIQNMGSEAQKKYWLPKMVSGEVVTAIAMTEA 127
++ V+E ++ G+ V + L + I G+E QK+ +L + GE + A +TE
Sbjct 70 IIAVEELSKV-CGTTGVILSAHTSLCASLINEHGTEEQKQKYLVPLAKGEKIGAYGLTEP 128
Query 128 NAGSDLQAIRTQAILKNEHYVIDGSKTFISNGLHADLIVLVAKTDPQARAKGISLFLVDA 187
NAG+D A +T A+L+ +HYVI+GSK FI+NG AD V+ A TD KGIS F+++
Sbjct 129 NAGTDSGAQQTVAVLEGDHYVINGSKIFITNGGVADTFVIFAMTDRTKGTKGISAFIIEK 188
Query 188 QLEGVEKGRSLKKIGLHAQDTAELFFDGVHVPVTQRLGQEGQGFAYLMQELPRERLSIAM 247
+G G+ +K+G+ A T EL F+ + VPV +G+EG+GF M+ L R+ IA
Sbjct 189 GFKGFSIGKVEQKLGIRASSTTELVFEDMIVPVENMIGKEGKGFPIAMKTLDGGRIGIAA 248
Query 248 MGMGSIWGAIDLTTSYVRERKAFGQTLAQLQNTRFVIANAQIKAKAAQAFIHECAQMYHQ 307
+G GA + +Y++ERK FG++L + Q +++A+ + ++A+ +++ A +
Sbjct 249 QALGIAEGAFNEARAYMKERKQFGRSLDKFQGLAWMMADMDVAIESARYLVYKAAYLKQA 308
Query 308 GALTVGHVAALKCFITDTQCDVIDQLLQLFGGYGYMQEYPISRFFVDSRVQKIYGGTNEI 367
G A K + DV + +QLFGGYGY ++YP+ R D+++ +IY GT+E+
Sbjct 309 GLPYTVDAARAKLHAANVAMDVTTKAVQLFGGYGYTKDYPVERMMRDAKITEIYEGTSEV 368
Query 368 MKEIVA 373
K +++
Sbjct 369 QKLVIS 374
>P45867 Acyl-CoA dehydrogenase [Bacillus subtilis (strain 168)]
Length=379
Score = 221 bits (564), Expect = 2e-72
Identities = 121/370 (33%), Positives = 205/370 (55%), Gaps = 3/370 (1%)
Query 6 DFELFRDTYKRFLNDHVAPYYEQWEHDGLIPRHIWNLLGENGFLCVDVPEEYGGYGAPVH 65
+ E+ R + F VAP + + R ++ + G + PE+YGG G+
Sbjct 8 EHEMIRKLVRDFAKHEVAPTAAERDEQERFDRELFREMANLGLTGIPWPEDYGGIGSDYL 67
Query 66 YSLMLVQETARAGFGSLAVAIGGQNELVSPYIQNMGSEAQKKYWLPKMVSGEVVTAIAMT 125
++ V+E ++ S V + L S + G+E QK +L ++ GE + A A+T
Sbjct 68 AYVIAVEELSKV-CASTGVTLSAHISLCSWPLFAFGTEEQKTEYLTQLALGEKIGAFALT 126
Query 126 EANAGSDLQAIRTQAILKNEHYVIDGSKTFISNGLHADLIVLVAKTDPQARAKGISLFLV 185
EA +GSD +++T A + YV++GSK FI+NG AD+ ++ A TDP+ + KG++ F+V
Sbjct 127 EAGSGSDAGSMKTTAERIGDDYVLNGSKVFITNGGVADIYIVFAVTDPEKKKKGVTAFIV 186
Query 186 DAQLEGVEKGRSLKKIGLHAQDTAELFFDGVHVPVTQRLGQEGQGFAYLMQELPRERLSI 245
+ EG G+ KK+G+ + T E+ F+ VP ++RLG+EG+GF M+ L R I
Sbjct 187 EKDFEGFFTGKKEKKLGIRSSPTTEIMFEDCVVPASKRLGEEGEGFKIAMKTLDGGRNGI 246
Query 246 AMMGMGSIWGAIDLTTSYVRERKAFGQTLAQLQNTRFVIANAQIKAKAAQAFIHECAQMY 305
A +G GA+D Y +ERK FG+++A+ Q F +A+ +A++ ++ A +
Sbjct 247 AAQAVGIAQGALDAALQYAKERKQFGKSIAEQQGIAFKLADMATMIEASRLLTYQAAWLE 306
Query 306 HQGALTVGHVAAL-KCFITDTQCDVIDQLLQLFGGYGYMQEYPISRFFVDSRVQKIYGGT 364
G L G +A+ K DT V + +Q+FGGYGY ++YP+ R+ D+++ +IY GT
Sbjct 307 SSG-LPYGKASAMSKLMAGDTAMKVTTEAVQIFGGYGYTKDYPVERYMRDAKITQIYEGT 365
Query 365 NEIMKEIVAR 374
EI + +++R
Sbjct 366 QEIQRLVISR 375
>Q9FS87 Isovaleryl-CoA dehydrogenase, mitochondrial [Solanum tuberosum]
Length=412
Score = 220 bits (561), Expect = 1e-71
Identities = 118/369 (32%), Positives = 208/369 (56%), Gaps = 3/369 (1%)
Query 10 FRDTYKRFLNDHVAPYYEQWEHDGLIPR--HIWNLLGENGFLCVDVPEEYGGYGAPVHYS 67
F+++ +F +++AP+ E+ + P+ ++W L+G L + VPEEYGG G Y
Sbjct 41 FKESVAQFAQENIAPHAEKIDRTNYFPQDVNLWKLMGNFNLLGITVPEEYGGLGLGYLYH 100
Query 68 LMLVQETARAGFGSLAVAIGGQNELVSPYIQNMGSEAQKKYWLPKMVSGEVVTAIAMTEA 127
+ ++E +RA GS+ ++ G L + G+ QK+ +LPK++SGE V A+AM+E
Sbjct 101 CIAMEEISRAS-GSVGLSYGAHTNLCINQLVRNGTHEQKQKYLPKLISGEHVGALAMSEP 159
Query 128 NAGSDLQAIRTQAILKNEHYVIDGSKTFISNGLHADLIVLVAKTDPQARAKGISLFLVDA 187
NAGSD+ +++ +A YV++G+K + +NG A +V+ AKTD A +KGI+ F+++
Sbjct 160 NAGSDVVSMKCKADRVEGGYVLNGNKMWCTNGPTAQTLVVYAKTDVTAGSKGITAFIIEK 219
Query 188 QLEGVEKGRSLKKIGLHAQDTAELFFDGVHVPVTQRLGQEGQGFAYLMQELPRERLSIAM 247
+ G + L K+G+ DT EL F+ VP LGQ G+G LM L ERL +A
Sbjct 220 GMTGFSTAQKLDKLGMRGSDTCELVFENCFVPEENVLGQVGRGVYVLMSGLDLERLVLAS 279
Query 248 MGMGSIWGAIDLTTSYVRERKAFGQTLAQLQNTRFVIANAQIKAKAAQAFIHECAQMYHQ 307
+G + +D+ YV++R+ FG+ + + Q + +A+ ++++++++ A+
Sbjct 280 GPVGIMQACLDVVLPYVKQREQFGRPIGEFQFVQGKVADMYTSMQSSRSYLYSVARECDS 339
Query 308 GALTVGHVAALKCFITDTQCDVIDQLLQLFGGYGYMQEYPISRFFVDSRVQKIYGGTNEI 367
G + A + + V Q +Q GG GY+ EYP RF D+++ +I GT+EI
Sbjct 340 GTINTKDCAGVILSAAERATQVALQAIQCLGGNGYVNEYPTGRFLRDAKLYEIGAGTSEI 399
Query 368 MKEIVARDV 376
+ I+ R++
Sbjct 400 RRMIIGREL 408
Score = 22.7 bits (47), Expect = 0.19
Identities = 29/120 (24%), Positives = 45/120 (38%), Gaps = 18/120 (15%)
Query 153 KTFISNGLHADLIVLVAKTDPQARAKGISLFLVDAQLEGVEKGRSL--KKIGLHAQ--DT 208
K F++ + + L + PQ A SL D Q + E + I HA+ D
Sbjct 3 KLFVARSVKSALFRIKNHQKPQFAAFSTSLLFDDTQKQFKESVAQFAQENIAPHAEKIDR 62
Query 209 AELF------------FDGVHVPVTQRLGQEGQGFAYLMQELPRERLSIAMMGMGSIWGA 256
F F+ + + V + G G G YL + E +S A +G +GA
Sbjct 63 TNYFPQDVNLWKLMGNFNLLGITVPEEYG--GLGLGYLYHCIAMEEISRASGSVGLSYGA 120
>G3KIM8 Acryloyl-CoA reductase (NADH) [Anaerotignum propionicum]
Length=394
Score = 218 bits (556), Expect = 4e-71
Identities = 123/373 (33%), Positives = 205/373 (55%), Gaps = 6/373 (2%)
Query 8 ELFRDTYKRFLNDHVAPYYEQWEHDGLIPRHIWNLLGENGFLCVDVPEEYGGYGAPVHYS 67
E+ + ++F + P E+ + + + P + + E G + +P+E+GG G
Sbjct 23 EMLKKLARQFAEIELEPVAEEIDREHVFPAENFKKMAEIGLTGIGIPKEFGGSGGGTLEK 82
Query 68 LMLVQETARAGFGSLAVAIGGQNELVSPY-IQNMGSEAQKKYWLPKMVSGEVVTAIAMTE 126
++ V E + S ++ L++P I G++ QK+ +LP++ G + A A+TE
Sbjct 83 VIAVSEFGKKCMASASIL---SIHLIAPQAIYKYGTKEQKETYLPRLTKGGELGAFALTE 139
Query 127 ANAGSDLQAIRTQAILKNE--HYVIDGSKTFISNGLHADLIVLVAKTDPQARAKGISLFL 184
NAGSD A++T AIL ++ YV++G+K FIS G A ++V+ A T+P+ KG+S +
Sbjct 140 PNAGSDAGAVKTTAILDSQTNEYVLNGTKCFISGGGRAGVLVIFALTEPKKGLKGMSAII 199
Query 185 VDAQLEGVEKGRSLKKIGLHAQDTAELFFDGVHVPVTQRLGQEGQGFAYLMQELPRERLS 244
V+ G G+ K+G+ +TAEL F+ VP LG+EG+GF M+ L R+
Sbjct 200 VEKGTPGFSIGKVESKMGIAGSETAELIFEDCRVPAANLLGKEGKGFKIAMEALDGARIG 259
Query 245 IAMMGMGSIWGAIDLTTSYVRERKAFGQTLAQLQNTRFVIANAQIKAKAAQAFIHECAQM 304
+ +G GAIDL+ YV ER FG+ +A LQ ++ IA+ K AA+A + A +
Sbjct 260 VGAQAIGIAEGAIDLSVKYVHERIQFGKPIANLQGIQWYIADMATKTAAARALVEFAAYL 319
Query 305 YHQGALTVGHVAALKCFITDTQCDVIDQLLQLFGGYGYMQEYPISRFFVDSRVQKIYGGT 364
G A K ++ V + LQ+ GGYGYM++YP+ R + D+++ +IY GT
Sbjct 320 EDAGKPFTKESAMCKLNASENARFVTNLALQIHGGYGYMKDYPLERMYRDAKITEIYEGT 379
Query 365 NEIMKEIVARDVL 377
+EI K ++AR+V+
Sbjct 380 SEIHKVVIAREVM 392
>P12007 Isovaleryl-CoA dehydrogenase, mitochondrial [Rattus norvegicus]
Length=424
Score = 216 bits (550), Expect = 8e-70
Identities = 120/368 (33%), Positives = 210/368 (57%), Gaps = 5/368 (1%)
Query 11 RDTYKRFLNDHVAPYYEQWE--HDGLIPRHIWNLLGENGFLCVDVPEEYGGYGAPVHYSL 68
R T +F+ +++AP ++ + +D R W LG G L + P +YGG G +
Sbjct 51 RHTISKFVQENLAPKAQEIDQSNDFKNLREFWKQLGSLGVLGITAPVQYGGSGLGYLEHV 110
Query 69 MLVQETARAGFGSLAVAIGGQNELVSPYIQNMGSEAQKKYWLPKMVSGEVVTAIAMTEAN 128
++++E +RA ++ ++ G + L I G+EAQK+ +LPK++SGE + A+AM+E N
Sbjct 111 LVMEEISRAS-AAVGLSYGAHSNLCINQIVRNGNEAQKEKYLPKLISGEFIGALAMSEPN 169
Query 129 AGSDLQAIRTQAILKNEHYVIDGSKTFISNGLHADLIVLVAKTDPQA--RAKGISLFLVD 186
AGSD+ ++R +A K +HYV++G+K +I+NG AD++V+ AKTD A ++GI+ F+V+
Sbjct 170 AGSDVVSMRLKAEKKGDHYVLNGNKFWITNGPDADVLVVYAKTDLTAVPASRGITAFIVE 229
Query 187 AQLEGVEKGRSLKKIGLHAQDTAELFFDGVHVPVTQRLGQEGQGFAYLMQELPRERLSIA 246
+ G + L K+G+ +T EL F+ VP L QE +G LM L ERL +A
Sbjct 230 KDMPGFSTSKKLDKLGMRGSNTCELVFEDCKVPAANILSQESKGVYVLMSGLDLERLVLA 289
Query 247 MMGMGSIWGAIDLTTSYVRERKAFGQTLAQLQNTRFVIANAQIKAKAAQAFIHECAQMYH 306
+G + +D T Y+ R+AFGQ + Q Q + +A+ + A + +++ A+
Sbjct 290 GGPLGIMQAVLDHTIPYLHVREAFGQKIGQFQLMQGKMADMYTRLMACRQYVYNVARACD 349
Query 307 QGALTVGHVAALKCFITDTQCDVIDQLLQLFGGYGYMQEYPISRFFVDSRVQKIYGGTNE 366
+G +T A + + + V +Q GG GY+ ++P+ RF D+++ +I GGT+E
Sbjct 350 EGHITAKDCAGVILYTAECATQVALDGIQCLGGNGYINDFPMGRFLRDAKLYEIGGGTSE 409
Query 367 IMKEIVAR 374
+ + ++ R
Sbjct 410 VRRLVIGR 417
>J7TF92 3-(aryl)acrylate reductase [Clostridium sporogenes (strain
ATCC 15579)]
Length=377
Score = 214 bits (546), Expect = 9e-70
Identities = 115/370 (31%), Positives = 200/370 (54%), Gaps = 1/370 (0%)
Query 8 ELFRDTYKRFLNDHVAPYYEQWEHDGLIPRHIWNLLGENGFLCVDVPEEYGGYGAPVHYS 67
EL R + F + P ++ + P+ I + +NGF + +P+EYGG GA
Sbjct 8 ELIRKLARDFAEQEIEPIADEVDKTAEFPKEIVKKMAQNGFFGIKMPKEYGGAGADNRAY 67
Query 68 LMLVQETARAGFGSLAVAIGGQNELVSPYIQNMGSEAQKKYWLPKMVSGEVVTAIAMTEA 127
+ +++E +RA G + + N L+ +G++ QK+ +L M+ GE A A+TE
Sbjct 68 VTIMEEISRAS-GVAGIYLSSPNSLLGTPFLLVGTDEQKEKYLKPMIRGEKTLAFALTEP 126
Query 128 NAGSDLQAIRTQAILKNEHYVIDGSKTFISNGLHADLIVLVAKTDPQARAKGISLFLVDA 187
AGSD A+ T A + ++Y+++G KTFI+ +D I++ AKTD KGI+ F+VD+
Sbjct 127 GAGSDAGAVATTAREEGDYYILNGRKTFITGAPISDNIIVFAKTDMSKGTKGITTFIVDS 186
Query 188 QLEGVEKGRSLKKIGLHAQDTAELFFDGVHVPVTQRLGQEGQGFAYLMQELPRERLSIAM 247
+ EGV G+ K+G+ T+++ + V V + LG+ +GF M+ L R+ +A
Sbjct 187 KQEGVSFGKPEDKMGMIGCPTSDIILENVKVHKSDILGELNKGFITAMKTLSVGRIGVAA 246
Query 248 MGMGSIWGAIDLTTSYVRERKAFGQTLAQLQNTRFVIANAQIKAKAAQAFIHECAQMYHQ 307
+G A+D Y ++RK F + +A+ Q +F +AN + K AA+ ++ A
Sbjct 247 QALGIAQAAVDEAVKYAKQRKQFNRPIAKFQAIQFKLANMETKLNAAKLLVYNAAYKMDC 306
Query 308 GALTVGHVAALKCFITDTQCDVIDQLLQLFGGYGYMQEYPISRFFVDSRVQKIYGGTNEI 367
G + K F ++ +++ LQ+ GGYGY+++Y I R + D RV IY GT+E+
Sbjct 307 GEKADKEASMAKYFAAESAIQIVNDALQIHGGYGYIKDYKIERLYRDVRVIAIYEGTSEV 366
Query 368 MKEIVARDVL 377
+ ++A ++L
Sbjct 367 QQMVIASNLL 376
Lambda K H a alpha
0.323 0.138 0.410 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1433576
Database: 02e97303b9208ee9fa3d9ebf5301b9bd.SwissProt.fasta
Posted date: May 18, 2024 11:48 AM
Number of letters in database: 4,894
Number of sequences in database: 12
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
