BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 5b6460d7fd4ef76464d3c74392ca44af.SwissProt.fasta
18 sequences; 5,706 total letters
Query= ACIAD1731
Length=276
Score E
Sequences producing significant alignments: (Bits) Value
P9WGP8 Putative oxidoreductase SadH [Mycobacterium tuberculosis (... 129 3e-39
P9WGP9 Putative oxidoreductase SadH [Mycobacterium tuberculosis (... 129 3e-39
P9WGS3 Probable oxidoreductase EphD [Mycobacterium tuberculosis (... 128 7e-37
P9WGS2 Probable oxidoreductase EphD [Mycobacterium tuberculosis (... 128 7e-37
P66778 Probable oxidoreductase EphD [Mycobacterium bovis (strain ... 128 7e-37
Q48436 Diacetyl reductase [(S)-acetoin forming] [Klebsiella pneum... 121 2e-36
Q04520 Diacetyl reductase [(S)-acetoin forming] [Raoultella terri... 117 4e-35
P0AET9 7alpha-hydroxysteroid dehydrogenase [Escherichia coli O157... 116 1e-34
P0AET8 7alpha-hydroxysteroid dehydrogenase [Escherichia coli (str... 116 1e-34
Q9WYG0 Uncharacterized oxidoreductase TM_0325 [Thermotoga maritim... 109 7e-32
P14802 Uncharacterized oxidoreductase YoxD [Bacillus subtilis (st... 108 1e-31
Q9F7E0 Cyclohexanol dehydrogenase [Acinetobacter sp. (strain SE19)] 108 2e-31
Q6GDV6 Uncharacterized oxidoreductase SAR2567 [Staphylococcus aur... 105 9e-31
Q7T2D1 Retinol dehydrogenase 10-B [Danio rerio] 106 3e-30
Q9XT00 (3R)-3-hydroxyacyl-CoA dehydrogenase [Sus scrofa] 102 4e-29
C8WJW0 3beta-hydroxysteroid dehydrogenase 1 [Eggerthella lenta (s... 102 5e-29
P51831 3-oxoacyl-[acyl-carrier-protein] reductase FabG [Bacillus ... 101 5e-29
Q9EQ06 Estradiol 17-beta-dehydrogenase 11 [Mus musculus] 102 5e-29
>P9WGP8 Putative oxidoreductase SadH [Mycobacterium tuberculosis
(strain CDC 1551 / Oshkosh)]
Length=276
Score = 129 bits (324), Expect = 3e-39
Identities = 83/264 (31%), Positives = 139/264 (53%), Gaps = 19/264 (7%)
Query 17 AVVTGAGSGIGRSFALELARRGGTVVCSDINLDAAKETVSLIQELGAQAFPVQCDVAKAE 76
AV+TGAGSGIGR+ AL L+ + + SD++ D +TV L Q LGAQ + DVA+ E
Sbjct 9 AVITGAGSGIGRALALNLSEKRAKLALSDVDTDGLAKTVRLAQALGAQVKSDRLDVAERE 68
Query 77 QVSQLAEHAEKLMQNPVTL--VINNAGIGLGGKFDEMTTEDWQWCLDINLWGVIHGCRAF 134
V HA+ ++ + T+ V NNAGI G D+ +D + +D++ WGV++G +AF
Sbjct 69 AV---LAHADAVVAHFGTVHQVYNNAGIAYNGNVDKSEFKDIERIIDVDFWGVVNGTKAF 125
Query 135 VPKFKQLGHGAIINVASAASFTAAPEMTVYNVSKAGVRALSETLSAEL--KKFDIKVNVL 192
+P G G I+N++S A P + YN +K VR +E L E+ + +KV +
Sbjct 126 LPHVIASGDGHIVNISSLFGLIAVPGQSAYNAAKFAVRGFTEALRQEMLVARHPVKVTCV 185
Query 193 CPTLVPTNIIKNGKV----PHKGILDYALNNLAFTTSDKVAKLTLDRLDKDKLYTIPQID 248
P + T + +N V + ++ LA + + AK ++ + K + + ++
Sbjct 186 HPGGIKTAVARNATVADGEDQQTFAEFFDRRLALHSPEMAAKTIVNGVAKGQARVVVGLE 245
Query 249 AKLFWLMKRAAPNLYAKFLGTSYR 272
AK A ++ A+ +G+SY+
Sbjct 246 AK--------AVDVLARIMGSSYQ 261
>P9WGP9 Putative oxidoreductase SadH [Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv)]
Length=276
Score = 129 bits (324), Expect = 3e-39
Identities = 83/264 (31%), Positives = 139/264 (53%), Gaps = 19/264 (7%)
Query 17 AVVTGAGSGIGRSFALELARRGGTVVCSDINLDAAKETVSLIQELGAQAFPVQCDVAKAE 76
AV+TGAGSGIGR+ AL L+ + + SD++ D +TV L Q LGAQ + DVA+ E
Sbjct 9 AVITGAGSGIGRALALNLSEKRAKLALSDVDTDGLAKTVRLAQALGAQVKSDRLDVAERE 68
Query 77 QVSQLAEHAEKLMQNPVTL--VINNAGIGLGGKFDEMTTEDWQWCLDINLWGVIHGCRAF 134
V HA+ ++ + T+ V NNAGI G D+ +D + +D++ WGV++G +AF
Sbjct 69 AV---LAHADAVVAHFGTVHQVYNNAGIAYNGNVDKSEFKDIERIIDVDFWGVVNGTKAF 125
Query 135 VPKFKQLGHGAIINVASAASFTAAPEMTVYNVSKAGVRALSETLSAEL--KKFDIKVNVL 192
+P G G I+N++S A P + YN +K VR +E L E+ + +KV +
Sbjct 126 LPHVIASGDGHIVNISSLFGLIAVPGQSAYNAAKFAVRGFTEALRQEMLVARHPVKVTCV 185
Query 193 CPTLVPTNIIKNGKV----PHKGILDYALNNLAFTTSDKVAKLTLDRLDKDKLYTIPQID 248
P + T + +N V + ++ LA + + AK ++ + K + + ++
Sbjct 186 HPGGIKTAVARNATVADGEDQQTFAEFFDRRLALHSPEMAAKTIVNGVAKGQARVVVGLE 245
Query 249 AKLFWLMKRAAPNLYAKFLGTSYR 272
AK A ++ A+ +G+SY+
Sbjct 246 AK--------AVDVLARIMGSSYQ 261
>P9WGS3 Probable oxidoreductase EphD [Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv)]
Length=592
Score = 128 bits (321), Expect = 7e-37
Identities = 74/185 (40%), Positives = 103/185 (56%), Gaps = 2/185 (1%)
Query 19 VTGAGSGIGRSFALELARRGGTVVCSDINLDAAKETVSLIQELGAQAFPVQCDVAKAEQV 78
VTGAGSGIGR AL AR G +V SDI+ K+T + I G A+P DV+ AE V
Sbjct 329 VTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAEIAARGGIAYPYVLDVSDAEAV 388
Query 79 SQLAEHAEKLMQNPVTLVINNAGIGLGGKFDEMTTEDWQWCLDINLWGVIHGCRAFVPKF 138
AE P +V+NNAGIG G+F + E + L +NL GV++GCRAF +
Sbjct 389 EAFAERVSAEHGVP-DIVVNNAGIGQAGRFLDTPAEQFDRVLAVNLGGVVNGCRAFGQRL 447
Query 139 KQLGHGA-IINVASAASFTAAPEMTVYNVSKAGVRALSETLSAELKKFDIKVNVLCPTLV 197
+ G G I+NV+S A++ ++ Y SKA S+ L AEL + + +CP ++
Sbjct 448 VERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCLRAELDAAGVGLTTICPGVI 507
Query 198 PTNII 202
TNI+
Sbjct 508 DTNIV 512
>P9WGS2 Probable oxidoreductase EphD [Mycobacterium tuberculosis
(strain CDC 1551 / Oshkosh)]
Length=592
Score = 128 bits (321), Expect = 7e-37
Identities = 74/185 (40%), Positives = 103/185 (56%), Gaps = 2/185 (1%)
Query 19 VTGAGSGIGRSFALELARRGGTVVCSDINLDAAKETVSLIQELGAQAFPVQCDVAKAEQV 78
VTGAGSGIGR AL AR G +V SDI+ K+T + I G A+P DV+ AE V
Sbjct 329 VTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAEIAARGGIAYPYVLDVSDAEAV 388
Query 79 SQLAEHAEKLMQNPVTLVINNAGIGLGGKFDEMTTEDWQWCLDINLWGVIHGCRAFVPKF 138
AE P +V+NNAGIG G+F + E + L +NL GV++GCRAF +
Sbjct 389 EAFAERVSAEHGVP-DIVVNNAGIGQAGRFLDTPAEQFDRVLAVNLGGVVNGCRAFGQRL 447
Query 139 KQLGHGA-IINVASAASFTAAPEMTVYNVSKAGVRALSETLSAELKKFDIKVNVLCPTLV 197
+ G G I+NV+S A++ ++ Y SKA S+ L AEL + + +CP ++
Sbjct 448 VERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCLRAELDAAGVGLTTICPGVI 507
Query 198 PTNII 202
TNI+
Sbjct 508 DTNIV 512
>P66778 Probable oxidoreductase EphD [Mycobacterium bovis (strain
ATCC BAA-935 / AF2122/97)]
Length=592
Score = 128 bits (321), Expect = 7e-37
Identities = 74/185 (40%), Positives = 103/185 (56%), Gaps = 2/185 (1%)
Query 19 VTGAGSGIGRSFALELARRGGTVVCSDINLDAAKETVSLIQELGAQAFPVQCDVAKAEQV 78
VTGAGSGIGR AL AR G +V SDI+ K+T + I G A+P DV+ AE V
Sbjct 329 VTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAEIAARGGIAYPYVLDVSDAEAV 388
Query 79 SQLAEHAEKLMQNPVTLVINNAGIGLGGKFDEMTTEDWQWCLDINLWGVIHGCRAFVPKF 138
AE P +V+NNAGIG G+F + E + L +NL GV++GCRAF +
Sbjct 389 EAFAERVSAEHGVP-DIVVNNAGIGQAGRFLDTPAEQFDRVLAVNLGGVVNGCRAFGQRL 447
Query 139 KQLGHGA-IINVASAASFTAAPEMTVYNVSKAGVRALSETLSAELKKFDIKVNVLCPTLV 197
+ G G I+NV+S A++ ++ Y SKA S+ L AEL + + +CP ++
Sbjct 448 VERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCLRAELDAAGVGLTTICPGVI 507
Query 198 PTNII 202
TNI+
Sbjct 508 DTNIV 512
>Q48436 Diacetyl reductase [(S)-acetoin forming] [Klebsiella pneumoniae]
Length=256
Score = 121 bits (303), Expect = 2e-36
Identities = 79/223 (35%), Positives = 117/223 (52%), Gaps = 5/223 (2%)
Query 17 AVVTGAGSGIGRSFALELARRGGTVVCSDINLDAAKETVSLIQELGAQAFPVQCDVAKAE 76
A+VTGAG GIG++ AL L + G V +D N AK S I + G +A V+ DV+ +
Sbjct 5 ALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGRAMAVKVDVSDRD 64
Query 77 QVSQLAEHAEKLMQNPVTLVINNAGIGLGGKFDEMTTEDWQWCLDINLWGVIHGCRAFVP 136
QV E A K + +++NNAG+ + +T E +IN+ GVI G +A V
Sbjct 65 QVFAAVEQARKTL-GGFDVIVNNAGVAPSTPIESITPEIVDKVYNINVKGVIWGIQAAVE 123
Query 137 KFKQLGHGA-IINVASAASFTAAPEMTVYNVSKAGVRALSETLSAELKKFDIKVNVLCPT 195
FK+ GHG IIN S A PE+ VY+ SK VR L++T + +L I VN CP
Sbjct 124 AFKKEGHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGITVNGYCPG 183
Query 196 LVPTNIIKNGKVPHKGILDYALNNLAFTTSDKVAKLTLDRLDK 238
+V T + + + + A L + T++ ++TL RL +
Sbjct 184 IVKTPMWAE---IDRQVSEAAGKPLGYGTAEFAKRITLGRLSE 223
>Q04520 Diacetyl reductase [(S)-acetoin forming] [Raoultella terrigena]
Length=241
Score = 117 bits (293), Expect = 4e-35
Identities = 70/187 (37%), Positives = 101/187 (54%), Gaps = 2/187 (1%)
Query 14 QAYAVVTGAGSGIGRSFALELARRGGTVVCSDINLDAAKETVSLIQELGAQAFPVQCDVA 73
Q A+VTGAG GIG++ AL L + G V +D N A + I + G +A ++ DV+
Sbjct 2 QKVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATATAVAAEINQAGGRAVAIKVDVS 61
Query 74 KAEQVSQLAEHAEKLMQNPVTLVINNAGIGLGGKFDEMTTEDWQWCLDINLWGVIHGCRA 133
+ +QV E A K + +++NNAGI + +T E +IN+ GVI G +A
Sbjct 62 RRDQVFAAVEQARKAL-GGFNVIVNNAGIAPSTPIESITEEIVDRVYNINVKGVIWGMQA 120
Query 134 FVPKFKQLGHGA-IINVASAASFTAAPEMTVYNVSKAGVRALSETLSAELKKFDIKVNVL 192
V FK+ GHG I+N S A PE+ VY+ SK VR L++T + +L I VN
Sbjct 121 AVEAFKKEGHGGKIVNACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGITVNGF 180
Query 193 CPTLVPT 199
CP +V T
Sbjct 181 CPGIVKT 187
>P0AET9 7alpha-hydroxysteroid dehydrogenase [Escherichia coli
O157:H7]
Length=255
Score = 116 bits (291), Expect = 1e-34
Identities = 67/192 (35%), Positives = 109/192 (57%), Gaps = 2/192 (1%)
Query 17 AVVTGAGSGIGRSFALELARRGGTVVCSDINLDAAKETVSLIQELGAQAFPVQCDVAKAE 76
A++TGAG+GIG+ A+ A G +VV SDIN DAA V IQ+LG QAF +CD+ +
Sbjct 14 AIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQ 73
Query 77 QVSQLAEHAEKLMQNPVTLVINNAGIGLGGKFDEMTTEDWQWCLDINLWGVIHGCRAFVP 136
++S LA+ A + V +++NNAG G G K +M D++ ++N++ H + P
Sbjct 74 ELSALADFAISKL-GKVDILVNNAG-GGGPKPFDMPMADFRRAYELNVFSFFHLSQLVAP 131
Query 137 KFKQLGHGAIINVASAASFTAAPEMTVYNVSKAGVRALSETLSAELKKFDIKVNVLCPTL 196
+ ++ G G I+ + S A+ MT Y SKA L ++ +L + +I+VN + P
Sbjct 132 EMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPGA 191
Query 197 VPTNIIKNGKVP 208
+ T+ +K+ P
Sbjct 192 ILTDALKSVITP 203
Score = 18.5 bits (36), Expect = 3.1
Identities = 9/53 (17%), Positives = 27/53 (51%), Gaps = 0/53 (0%)
Query 13 QQAYAVVTGAGSGIGRSFALELARRGGTVVCSDINLDAAKETVSLIQELGAQA 65
++AY + + + + A E+ + GG V+ + ++ A + +++ ++A
Sbjct 112 RRAYELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKA 164
>P0AET8 7alpha-hydroxysteroid dehydrogenase [Escherichia coli
(strain K12)]
Length=255
Score = 116 bits (291), Expect = 1e-34
Identities = 67/192 (35%), Positives = 109/192 (57%), Gaps = 2/192 (1%)
Query 17 AVVTGAGSGIGRSFALELARRGGTVVCSDINLDAAKETVSLIQELGAQAFPVQCDVAKAE 76
A++TGAG+GIG+ A+ A G +VV SDIN DAA V IQ+LG QAF +CD+ +
Sbjct 14 AIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQ 73
Query 77 QVSQLAEHAEKLMQNPVTLVINNAGIGLGGKFDEMTTEDWQWCLDINLWGVIHGCRAFVP 136
++S LA+ A + V +++NNAG G G K +M D++ ++N++ H + P
Sbjct 74 ELSALADFAISKL-GKVDILVNNAG-GGGPKPFDMPMADFRRAYELNVFSFFHLSQLVAP 131
Query 137 KFKQLGHGAIINVASAASFTAAPEMTVYNVSKAGVRALSETLSAELKKFDIKVNVLCPTL 196
+ ++ G G I+ + S A+ MT Y SKA L ++ +L + +I+VN + P
Sbjct 132 EMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPGA 191
Query 197 VPTNIIKNGKVP 208
+ T+ +K+ P
Sbjct 192 ILTDALKSVITP 203
Score = 18.5 bits (36), Expect = 3.1
Identities = 9/53 (17%), Positives = 27/53 (51%), Gaps = 0/53 (0%)
Query 13 QQAYAVVTGAGSGIGRSFALELARRGGTVVCSDINLDAAKETVSLIQELGAQA 65
++AY + + + + A E+ + GG V+ + ++ A + +++ ++A
Sbjct 112 RRAYELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKA 164
>Q9WYG0 Uncharacterized oxidoreductase TM_0325 [Thermotoga maritima
(strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826
/ MSB8)]
Length=251
Score = 109 bits (272), Expect = 7e-32
Identities = 68/184 (37%), Positives = 104/184 (57%), Gaps = 7/184 (4%)
Query 13 QQAYAVVTGAGSGIGRSFALELARRGGTVVCSDINLDAAKETVSLIQELGAQAFPVQCDV 72
Q ++TGAGSGIG+ A+ A RG V +DI+ + KETV LI+ +G +A + DV
Sbjct 4 QGKVVLITGAGSGIGKKAAVMFAERGAKVAINDISEEKGKETVELIKSMGGEAAFIFGDV 63
Query 73 AK-AEQ-VSQLAEHAEKLMQNPVTLVINNAGIGLGGKFDEMTTEDWQWCLDINLWGVIHG 130
AK AEQ V + E +L +++NNAGI G +E + ED+ + +N+ G
Sbjct 64 AKDAEQIVKKTVETFGRL-----DILVNNAGIVPYGNIEETSEEDFDKTMAVNVKGPFLL 118
Query 131 CRAFVPKFKQLGHGAIINVASAASFTAAPEMTVYNVSKAGVRALSETLSAELKKFDIKVN 190
+ V + K+ G G I+NV+S A P VY+VSKA + L+ +L+ + + I+VN
Sbjct 119 SKYAVEQMKKQGGGVIVNVSSEAGLIGIPRRCVYSVSKAALLGLTRSLAVDYVDYGIRVN 178
Query 191 VLCP 194
+CP
Sbjct 179 AVCP 182
>P14802 Uncharacterized oxidoreductase YoxD [Bacillus subtilis
(strain 168)]
Length=238
Score = 108 bits (269), Expect = 1e-31
Identities = 65/192 (34%), Positives = 110/192 (57%), Gaps = 7/192 (4%)
Query 13 QQAYAVVTGAGSGIGRSFALELARRG---GTVVCSDINLDAAKETVSLIQELGAQAFPVQ 69
Q A++TG G GIGR+ AL LA+ G G + + N++ E V + LG +A
Sbjct 5 QHKTALITGGGRGIGRATALALAKEGVNIGLIGRTSANVEKVAEEV---KALGVKAAFAA 61
Query 70 CDVAKAEQVSQLAEHAEKLMQNPVTLVINNAGIGLGGKFDEMTTEDWQWCLDINLWGVIH 129
DV A+QV+Q ++ + + + ++INNAGI G F +++ ++W+ + +NL GV H
Sbjct 62 ADVKDADQVNQAVAQVKEQLGD-IDILINNAGISKFGGFLDLSADEWENIIQVNLMGVYH 120
Query 130 GCRAFVPKFKQLGHGAIINVASAASFTAAPEMTVYNVSKAGVRALSETLSAELKKFDIKV 189
RA +P+ + G IIN++S A A + Y+ SK V L+E+L E++K +I+V
Sbjct 121 VTRAVLPEMIERKAGDIINISSTAGQRGAAVTSAYSASKFAVLGLTESLMQEVRKHNIRV 180
Query 190 NVLCPTLVPTNI 201
+ L P+ V +++
Sbjct 181 SALTPSTVASDM 192
>Q9F7E0 Cyclohexanol dehydrogenase [Acinetobacter sp. (strain
SE19)]
Length=251
Score = 108 bits (269), Expect = 2e-31
Identities = 77/237 (32%), Positives = 118/237 (50%), Gaps = 11/237 (5%)
Query 17 AVVTGAGSGIGRSFALELARRGGTVVCSDINLDAAKETVSLIQELGAQAFPVQCDVAKAE 76
A++TGAGSGIG+S AL LA++G +VV SDINL+AA++ V I LG +A + + A+ E
Sbjct 14 ALITGAGSGIGKSTALLLAQQGVSVVVSDINLEAAQKVVDEIVALGGKAAANKANTAEPE 73
Query 77 QVSQLAEHAEKLMQNPVTLVINNAGI-GLGGKFDEMTTEDWQWCLDINLWGVIHGCRAFV 135
+ E A + L NNAGI G +E++ E W+ +D+NL V + V
Sbjct 74 DMKAAVEFAVSTF-GALHLAFNNAGILGEVNSTEELSIEGWRRVIDVNLNAVFYSMHYEV 132
Query 136 PKFKQLGHGAIINVASAASFTAAPEMTVYNVSKAGVRALSETLSAELKKFDIKVNVLCPT 195
P G GAI+N AS A ++ Y +K GV L++ + E I++N + P
Sbjct 133 PAILAAGGGAIVNTASIAGLIGIQNISGYVAAKHGVTGLTKAAALEYADKGIRINSVHPG 192
Query 196 LVPT---------NIIKNGKVPHKGILDYALNNLAFTTSDKVAKLTLDRLDKDKLYT 243
+ T ++K + G + +AF SD + +T + D YT
Sbjct 193 YIKTPLIAEFEEAEMVKLHPIGRLGQPEEVAQVVAFLLSDDASFVTGSQYVVDGAYT 249
>Q6GDV6 Uncharacterized oxidoreductase SAR2567 [Staphylococcus
aureus (strain MRSA252)]
Length=231
Score = 105 bits (263), Expect = 9e-31
Identities = 60/185 (32%), Positives = 98/185 (53%), Gaps = 3/185 (2%)
Query 17 AVVTGAGSGIGRSFALELARRGGTVVCSDINLDAAKETVSLIQELGAQAFPVQCDVAKAE 76
AVVTGAGSGIG + A L G VV + N D + + + + + P DV K E
Sbjct 9 AVVTGAGSGIGEAIATLLHEEGAKVVLAGRNKDKLQNVANQLAQDSVKVVPT--DVTKKE 66
Query 77 QVSQLAEHAEKLMQNPVTLVINNAGIGLGGKFDEMTTEDWQWCLDINLWGVIHGCRAFVP 136
+V +L + A++ + +VIN+AG L K + ++W +D+N+ G ++ +A +P
Sbjct 67 EVDELIKMAQQTFGG-LDIVINSAGQMLSSKITDYQVDEWDSMIDVNIKGTLYTAKAALP 125
Query 137 KFKQLGHGAIINVASAASFTAAPEMTVYNVSKAGVRALSETLSAELKKFDIKVNVLCPTL 196
+ G +IN+AS + F T+Y+ +KA V +++ L EL K +KV + P +
Sbjct 126 TMLEQSSGHLINIASISGFEVTKSSTIYSATKAAVHTITQGLEKELAKTGVKVTSISPGM 185
Query 197 VPTNI 201
V T I
Sbjct 186 VDTAI 190
>Q7T2D1 Retinol dehydrogenase 10-B [Danio rerio]
Length=336
Score = 106 bits (265), Expect = 3e-30
Identities = 76/229 (33%), Positives = 108/229 (47%), Gaps = 24/229 (10%)
Query 2 KLFSSQHKKPSQQAYAVVTGAGSGIGRSFALELARRGGTVVCSDINLDAAKETVSLIQEL 61
K F +K + V+TGAGSG+GR FALE ARR T+V DIN + +ET + +E+
Sbjct 24 KWFIRPREKSVEGQVCVITGAGSGLGRLFALEFARRRATLVLWDINRQSNEETAEMAREI 83
Query 62 GAQAFP--------------------VQCDVAKAEQVSQLAEHAEKLMQNPVTLVINNAG 101
Q P CDV+K E V AE + + L+INNAG
Sbjct 84 YRQLKPSTGSSDSVQELPLLQPKVYTYMCDVSKRESVYLTAEKVRSEV-GDIDLLINNAG 142
Query 102 IGLGGKFDEMTTEDWQWCLDINLWGVIHGCRAFVPKFKQLGHGAIINVASAASFTAAPEM 161
+ G + E + + +N +AF+PK +L HG I+ VAS+ +
Sbjct 143 VVSGRHLLDCPDELIERTMMVNCHAHFWTTKAFLPKMLELNHGHIVTVASSLGLFTTAGV 202
Query 162 TVYNVSKAGVRALSETLSAELKKFD---IKVNVLCPTLVPTNIIKNGKV 207
Y SK G E+LS ELK D IK+ ++CP LV T + + K+
Sbjct 203 EDYCASKFGAIGFHESLSHELKAADKDGIKMTLVCPFLVDTGMFEGCKI 251
>Q9XT00 (3R)-3-hydroxyacyl-CoA dehydrogenase [Sus scrofa]
Length=259
Score = 102 bits (253), Expect = 4e-29
Identities = 72/210 (34%), Positives = 112/210 (53%), Gaps = 11/210 (5%)
Query 13 QQAYAVVTGAGSGIGRSFALELARRGGTVVCSDINLDAAKETVSLI----QELGAQAFPV 68
+ A A+VTGAGSGIGR+ ++ LA G V D++ AA+ETV L+ E GA + P+
Sbjct 8 RSALALVTGAGSGIGRAVSVRLAAEGAAVAACDLDGAAAQETVQLLGGPGSEKGAPSGPM 67
Query 69 ---QCDVAKAEQVSQLAEHAEKLMQNPVTLVINNAGIGLGGKFDEMTTEDWQWCLDINLW 125
Q DV++AE +L E + P ++V++ AGI M+ +DW + +NL
Sbjct 68 AAFQADVSEAETARRLLEQVQAYFFRPPSVVVSCAGITRDEFLLRMSEDDWDKVIAVNLK 127
Query 126 GVIHGCRAFVPKFKQLG-HGAIINVASAASFTAAPEMTVYNVSKAGVRALSETLSAELKK 184
G+ +A G G+IIN++S T Y SKAGV L++ ++ EL +
Sbjct 128 GIFLVTQAAAQALVSSGCPGSIINISSIIGKVGNMGQTNYAASKAGVIGLTQAVARELGR 187
Query 185 FDIKVNVLCPTLVPTNIIKNGKVPHKGILD 214
+ I+ N + P + T + + KVP K +LD
Sbjct 188 YRIRCNSVLPGFIKTPMAQ--KVPQK-VLD 214
>C8WJW0 3beta-hydroxysteroid dehydrogenase 1 [Eggerthella lenta
(strain ATCC 25559 / DSM 2243 / CCUG 17323 / JCM 9979 / KCTC
3265 / NCTC 11813 / VPI 0255 / 1899 B)]
Length=261
Score = 102 bits (253), Expect = 5e-29
Identities = 68/186 (37%), Positives = 95/186 (51%), Gaps = 3/186 (2%)
Query 18 VVTGAGSGIGRSFALELARRGGTVVCS-DINLDAAKETVSLIQELGAQAFPVQCDVAKAE 76
VVTG+ G+G + A G VV + + + A+ETV I+E G A VQ DV+K E
Sbjct 11 VVTGSSKGLGAAMARRFGAEGMNVVANYRSDEEGARETVRAIEEAGGAAAAVQADVSKNE 70
Query 77 QVSQLAEHAEKLMQNPVTLVINNAGIGLGGKFDEMTTEDWQWCLDINLWGVIHGCRAFVP 136
V L + A V + +NNAGI + D + E+WQ +D+NL GV GCR +
Sbjct 71 CVDALFD-AAMFSFGGVDIWVNNAGIEVASPSDRKSIEEWQRVIDVNLTGVFAGCRRAID 129
Query 137 KF-KQLGHGAIINVASAASFTAAPEMTVYNVSKAGVRALSETLSAELKKFDIKVNVLCPT 195
F + G IIN++S P Y SKAGV L++TL+ E I+VN + P
Sbjct 130 HFLDRKMPGVIINLSSVHEIIPWPHFADYAASKAGVGMLTKTLALEYADRGIRVNAIAPG 189
Query 196 LVPTNI 201
+ T I
Sbjct 190 AMNTPI 195
Score = 18.1 bits (35), Expect = 4.1
Identities = 12/37 (32%), Positives = 19/37 (51%), Gaps = 3/37 (8%)
Query 5 SSQHKKPSQQAYAVVTGAGSGIG---RSFALELARRG 38
SS H+ +A + +G+G ++ ALE A RG
Sbjct 144 SSVHEIIPWPHFADYAASKAGVGMLTKTLALEYADRG 180
>P51831 3-oxoacyl-[acyl-carrier-protein] reductase FabG [Bacillus
subtilis (strain 168)]
Length=246
Score = 101 bits (252), Expect = 5e-29
Identities = 62/186 (33%), Positives = 99/186 (53%), Gaps = 2/186 (1%)
Query 17 AVVTGAGSGIGRSFALELARRGGTVVCSDINLDA-AKETVSLIQELGAQAFPVQCDVAKA 75
A+VTGA GIGRS AL+LA+ G VV + +A A E V I+ +G +A V+ DV+
Sbjct 7 AIVTGASRGIGRSIALDLAKSGANVVVNYSGNEAKANEVVDEIKSMGRKAIAVKADVSNP 66
Query 76 EQVSQLAEHAEKLMQNPVTLVINNAGIGLGGKFDEMTTEDWQWCLDINLWGVIHGCRAFV 135
E V + + + + +++NNAGI M ++W ++INL GV + +A
Sbjct 67 EDVQNMIKETLSVFST-IDILVNNAGITRDNLIMRMKEDEWDDVININLKGVFNCTKAVT 125
Query 136 PKFKQLGHGAIINVASAASFTAAPEMTVYNVSKAGVRALSETLSAELKKFDIKVNVLCPT 195
+ + G IINV+S + P Y +KAGV L+++ + EL +I VN + P
Sbjct 126 RQMMKQRSGRIINVSSIVGVSGNPGQANYVAAKAGVIGLTKSSAKELASRNITVNAIAPG 185
Query 196 LVPTNI 201
+ T++
Sbjct 186 FISTDM 191
Score = 21.6 bits (44), Expect = 0.32
Identities = 12/31 (39%), Positives = 14/31 (45%), Gaps = 0/31 (0%)
Query 11 PSQQAYAVVTGAGSGIGRSFALELARRGGTV 41
P Q Y G+ +S A ELA R TV
Sbjct 149 PGQANYVAAKAGVIGLTKSSAKELASRNITV 179
>Q9EQ06 Estradiol 17-beta-dehydrogenase 11 [Mus musculus]
Length=298
Score = 102 bits (255), Expect = 5e-29
Identities = 70/210 (33%), Positives = 111/210 (53%), Gaps = 10/210 (5%)
Query 1 MKLFSSQHKKPSQQAYAVVTGAGSGIGRSFALELARRGGTVVCSDINLDAAKETVSLIQE 60
+KLF + KK ++TGAG GIGR A E A+ +V DIN + +ET + ++
Sbjct 23 VKLFIPKKKKSVAGEIVLITGAGHGIGRLTAYEFAKLNTKLVLWDINKNGIEETAAKCRK 82
Query 61 LGAQAFPVQCDVAKAEQVSQLAEHAEKLMQNPVTLVINNAGIGLGGKFDEMTTEDWQ--W 118
LGAQA P D ++ E++ A+ ++ + V++++NNAG+ D T+D Q
Sbjct 83 LGAQAHPFVVDCSQREEIYSAAKKVKEEV-GDVSILVNNAGVVYTA--DLFATQDPQIEK 139
Query 119 CLDINLWGVIHGCRAFVPKFKQLGHGAIINVASAASFTAAPEMTVYNVSKAGV----RAL 174
++N+ +AF+P + HG I+ VASAA T P + Y SK RAL
Sbjct 140 TFEVNVLAHFWTTKAFLPVMMKNNHGHIVTVASAAGHTVVPFLLAYCSSKFAAVGFHRAL 199
Query 175 SETLSAELKKFDIKVNVLCPTLVPTNIIKN 204
++ L+A L + ++ + LCP + T IKN
Sbjct 200 TDELAA-LGRTGVRTSCLCPNFINTGFIKN 228
Lambda K H a alpha
0.321 0.135 0.400 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1121940
Database: 5b6460d7fd4ef76464d3c74392ca44af.SwissProt.fasta
Posted date: May 20, 2024 1:44 AM
Number of letters in database: 5,706
Number of sequences in database: 18
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
