BLASTP 2.12.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: a73f68e6326022f0d85c1d70d8970963.SwissProt.fasta
           16 sequences; 4,215 total letters



Query= ACIAD1829

Length=368
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

P77467 1,2-epoxyphenylacetyl-CoA isomerase [Escherichia coli (str...  231     6e-78
P24162 Probable enoyl-CoA hydratase [Rhodobacter capsulatus (stra...  194     9e-64
Q8DR19 Trans-2-decenoyl-[acyl-carrier-protein] isomerase [Strepto...  153     8e-48
Q8DSN0 Trans-2-decenoyl-[acyl-carrier-protein] isomerase [Strepto...  149     5e-46
P76082 2,3-dehydroadipyl-CoA hydratase [Escherichia coli (strain ...  138     5e-42
A4YI89 3-hydroxypropionyl-coenzyme A dehydratase [Metallosphaera ...  132     9e-40
P9WNN9 Probable enoyl-CoA hydratase EchA8 [Mycobacterium tubercul...  123     2e-36
P9WNN8 Probable enoyl-CoA hydratase echA8 [Mycobacterium tubercul...  123     2e-36
P64017 Probable enoyl-CoA hydratase echA8 [Mycobacterium bovis (s...  123     2e-36
P34559 Probable enoyl-CoA hydratase, mitochondrial [Caenorhabditi...  123     5e-36
Q1ZXF1 Probable enoyl-CoA hydratase, mitochondrial [Dictyostelium...  122     5e-36
O07533 Putative enoyl-CoA hydratase/isomerase YhaR [Bacillus subt...  119     9e-35
Q0AVM1 Crotonyl-CoA hydratase [Syntrophomonas wolfei subsp. wolfe...  117     3e-34
P30084 Enoyl-CoA hydratase, mitochondrial [Homo sapiens]              117     5e-34
Q52995 Probable enoyl-CoA hydratase [Rhizobium meliloti (strain 1...  113     1e-32
O34893 Putative enoyl-CoA hydratase/isomerase YngF [Bacillus subt...  112     3e-32


>P77467 1,2-epoxyphenylacetyl-CoA isomerase [Escherichia coli 
(strain K12)]
Length=262

 Score = 231 bits (589),  Expect = 6e-78
 Identities = 121/253 (48%), Positives = 155/253 (61%), Gaps = 2/253 (1%)

Query  117  EHGYTVITLNRPEKLNALTRPMLQALKDAVLAATQDHACRAILITGNGRGFCTGQDLNER  176
            E G   +TLNRPE+LN+    M   L + +    +D   R +L+TG GRGFC GQDLN+R
Sbjct  10   EKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDR  69

Query  177  R--DLEQAVDLGESLIQFYNPIITAIDQANKPVVCAVNGVAAGAGVGLALACDIVLAADD  234
                   A DLG S+ +FYNP++  + +  KPV+CAVNGVAAGAG  LAL  DIV+AA  
Sbjct  70   NVDPTGPAPDLGMSVERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAARS  129

Query  235  ARFIQSFSKIGLAPDAGISWHLPRLIGSARTKALTILAEPISAVQAQEWGMIWATLPSEK  294
            A+F+ +FSK+GL PD G +W LPR+ G AR   L +L   +SA QA EWGMIW  +  E 
Sbjct  130  AKFVMAFSKLGLIPDCGGTWLLPRVAGRARAMGLALLGNQLSAEQAHEWGMIWQVVDDET  189

Query  295  LHSEAEALVKQLSQRPTLSFAAIKQAHRSTAINTLQQQLDLEATLQQKVGWSEDYKRGVQ  354
            L   A+ L + L+ +PT     IKQA  S   NTL  QLDLE   Q+  G S DY+ GV 
Sbjct  190  LADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLAGRSADYREGVS  249

Query  355  AFFDGTTAQFTGQ  367
            AF    + QFTG+
Sbjct  250  AFLAKRSPQFTGK  262


>P24162 Probable enoyl-CoA hydratase [Rhodobacter capsulatus (strain 
ATCC BAA-309 / NBRC 16581 / SB1003)]
Length=257

 Score = 194 bits (494),  Expect = 9e-64
 Identities = 108/249 (43%), Positives = 150/249 (60%), Gaps = 4/249 (2%)

Query  119  GYTVITLNRPEKLNALTRPMLQALKDAVLAATQDHACRAILITGNGRGFCTGQDLNERRD  178
            G  VITL+RPE +NAL   M   L  A+  A  +   RAI++TG+GR FC+GQDL +   
Sbjct  13   GLAVITLDRPEVMNALNAAMRHELTAALHRARGE--ARAIVLTGSGRAFCSGQDLGD--G  68

Query  179  LEQAVDLGESLIQFYNPIITAIDQANKPVVCAVNGVAAGAGVGLALACDIVLAADDARFI  238
              + ++L   L + Y P++ AI     PV+ AVNG AAGAG  LALA D+V+AA  A F+
Sbjct  69   AAEGLNLETVLREEYEPLLQAIYSCPLPVLAAVNGAAAGAGANLALAADVVIAAQSAAFM  128

Query  239  QSFSKIGLAPDAGISWHLPRLIGSARTKALTILAEPISAVQAQEWGMIWATLPSEKLHSE  298
            Q+F++IGL PDAG +W LPR +G AR   + + AE I A +A   G+IW  +P       
Sbjct  129  QAFTRIGLMPDAGGTWWLPRQVGMARAMGMALFAEKIGAEEAARMGLIWEAVPDVDFEHH  188

Query  299  AEALVKQLSQRPTLSFAAIKQAHRSTAINTLQQQLDLEATLQQKVGWSEDYKRGVQAFFD  358
              A    L++ P+ +FAA+K+A  +   N L  QL LEA LQ ++G S D++ GVQAF +
Sbjct  189  WRARAAHLARGPSAAFAAVKKAFHAGLSNPLPAQLALEARLQGELGQSADFREGVQAFLE  248

Query  359  GTTAQFTGQ  367
                 FTG+
Sbjct  249  KRPPHFTGR  257


>Q8DR19 Trans-2-decenoyl-[acyl-carrier-protein] isomerase [Streptococcus 
pneumoniae (strain ATCC BAA-255 / R6)]
Length=261

 Score = 153 bits (387),  Expect = 8e-48
 Identities = 93/261 (36%), Positives = 141/261 (54%), Gaps = 8/261 (3%)

Query  112  VVVRQEHGYTVITLNRPEKLNALTRPMLQALKDAVLAATQDHACRAILITGNGRGFCTGQ  171
            ++ + E    ++TLNRPE  N    PM + + +A+  A ++ A   ILI  NG+ F  G 
Sbjct  4    IIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEENPAVHFILINANGKVFSVGG  63

Query  172  DLNERRDLEQAVDLGE-----SLIQFYNPIITAIDQANKPVVCAVNGVAAGAGVGLALAC  226
            DL E   +++AVD  +      + +  N I   I Q  KPV+  V+G  AGA   +A+A 
Sbjct  64   DLVE---MKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVLMEVDGAVAGAAANMAVAA  120

Query  227  DIVLAADDARFIQSFSKIGLAPDAGISWHLPRLIGSARTKALTILAEPISAVQAQEWGMI  286
            D  LA D A+FIQ+F  +GLAPDAG    L R IG  R   L +  E ++A +A EWG++
Sbjct  121  DFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAAQLAMTGEALTAEKALEWGLV  180

Query  287  WATLPSEKLHSEAEALVKQLSQRPTLSFAAIKQAHRSTAINTLQQQLDLEATLQQKVGWS  346
            +    +EKL    E L+K+L +  + S+AAIK+    +     Q    LE  LQ+ +  +
Sbjct  181  YRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWESQFKDWQGYATLELNLQKSLAQT  240

Query  347  EDYKRGVQAFFDGTTAQFTGQ  367
            ED+K GV+A  +    +F G+
Sbjct  241  EDFKEGVRAHSERRRPKFIGK  261


>Q8DSN0 Trans-2-decenoyl-[acyl-carrier-protein] isomerase [Streptococcus 
mutans serotype c (strain ATCC 700610 / UA159)]
Length=263

 Score = 149 bits (375),  Expect = 5e-46
 Identities = 86/259 (33%), Positives = 143/259 (55%), Gaps = 4/259 (2%)

Query  112  VVVRQEHGYTVITLNRPEKLNALTRPMLQALKDAVLAATQDHACRAILITGNGRGFCTGQ  171
            ++   ++G   +TLNRPE  N    P+ + +  A+  A +D   + +LI  NG+ F  G 
Sbjct  6    ILYNVDNGVATLTLNRPEVSNGFNIPICEEILKAIDIAKKDDTVQILLINANGKVFSVGG  65

Query  172  DLNERRDLEQAVDLGESLI---QFYNPIITAIDQANKPVVCAVNGVAAGAGVGLALACDI  228
            DL E +    A D+ +SL+   +  N I  A+ +  KPVV + +G  AGA   +A+A D 
Sbjct  66   DLVEMQRAVDADDV-QSLVRIAELVNKISFALKRLPKPVVMSTDGAVAGAAANIAVAADF  124

Query  229  VLAADDARFIQSFSKIGLAPDAGISWHLPRLIGSARTKALTILAEPISAVQAQEWGMIWA  288
             +A+D  RFIQ+F  +GLAPDAG  + L R IG  R   L +  E ++A +A E+G+++ 
Sbjct  125  CIASDKTRFIQAFVNVGLAPDAGGLFLLTRAIGITRATQLAMTGEALNAEKALEYGIVYK  184

Query  289  TLPSEKLHSEAEALVKQLSQRPTLSFAAIKQAHRSTAINTLQQQLDLEATLQQKVGWSED  348
                EKL    + ++ +L +    S+ AIK+    ++    Q+  DLE  LQ+ + ++ D
Sbjct  185  VCEPEKLEKITDRVITRLKRGSVNSYKAIKEMVWQSSFAGWQEYEDLELELQKSLAFTND  244

Query  349  YKRGVQAFFDGTTAQFTGQ  367
            +K GV+A+ +    +FTG+
Sbjct  245  FKEGVRAYTEKRRPKFTGK  263


>P76082 2,3-dehydroadipyl-CoA hydratase [Escherichia coli (strain 
K12)]
Length=255

 Score = 138 bits (347),  Expect = 5e-42
 Identities = 89/257 (35%), Positives = 132/257 (51%), Gaps = 5/257 (2%)

Query  111  LVVVRQEHGYTVITLNRPEKLNALTRPMLQALKDAVLAATQDHACRAILITGNGRGFCTG  170
            L+V RQ+    ++TLNRP   NAL   +L  L + + AA  D +    +ITGN R F  G
Sbjct  4    LIVSRQQR-VLLLTLNRPAARNALNNALLMQLVNELEAAATDTSISVCVITGNARFFAAG  62

Query  171  QDLNERRDLEQAVDLGESLIQFYNPIITAIDQANKPVVCAVNGVAAGAGVGLALACDIVL  230
             DLNE  + + A  L ++  Q +      +   NKP++ AVNG A GAG  LAL CD+V+
Sbjct  63   ADLNEMAEKDLAATLNDTRPQLW----ARLQAFNKPLIAAVNGYALGAGCELALLCDVVV  118

Query  231  AADDARFIQSFSKIGLAPDAGISWHLPRLIGSARTKALTILAEPISAVQAQEWGMIWATL  290
            A ++ARF      +G+ P AG +  L R +G +    + +  E I+A QAQ+ G++    
Sbjct  119  AGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASKMVLSGESITAQQAQQAGLVSDVF  178

Query  291  PSEKLHSEAEALVKQLSQRPTLSFAAIKQAHRSTAINTLQQQLDLEATLQQKVGWSEDYK  350
            PS+     A  L  ++++   L+  A KQA R +    LQ  L  E  L   +  +ED  
Sbjct  179  PSDLTLEYALQLASKMARHSPLALQAAKQALRQSQEVALQAGLAQERQLFTLLAATEDRH  238

Query  351  RGVQAFFDGTTAQFTGQ  367
             G+ AF    T  F G+
Sbjct  239  EGISAFLQKRTPDFKGR  255


>A4YI89 3-hydroxypropionyl-coenzyme A dehydratase [Metallosphaera 
sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 
/ TH2)]
Length=259

 Score = 132 bits (332),  Expect = 9e-40
 Identities = 86/265 (32%), Positives = 133/265 (50%), Gaps = 12/265 (5%)

Query  108  EQSLVVVRQEHGYTVITLNRPEKLNALTRPMLQALKDAVLAATQDHACRAILITGNGRGF  167
            E   +  ++E     ITLNRP+KLNAL   +L+ L  AV  A  D   R I+ITG G+ F
Sbjct  2    EFETIETKKEGNLFWITLNRPDKLNALNAKLLEELDRAVSQAESDPEIRVIIITGKGKAF  61

Query  168  CTGQDLNERRDLEQAVDLGESLIQFYNPIITAIDQANKPVVCAVNGVAAGAGVGLALACD  227
            C G D+ +   L  A     S  +    I+  I+  +KP +  +NG A G G+ LALACD
Sbjct  62   CAGADITQFNQLTPAEAWKFS--KKGREIMDKIEALSKPTIAMINGYALGGGLELALACD  119

Query  228  IVLAADDARFIQSFSKIGLAPDAGISWHLPRLIGSARTKALTILAEPISAVQAQEWGMIW  287
            I +AA++A+       +G+ P  G +  L R+IG  R   + +  + I    A+++G++ 
Sbjct  120  IRIAAEEAQLGLPEINLGIYPGYGGTQRLTRVIGKGRALEMMMTGDRIPGKDAEKYGLVN  179

Query  288  ATLPSEKLHSEAEALVKQLSQRPTLSFAAIKQAHRSTAINTLQQQLDLEATLQQKVGW--  345
              +P   L  E   L ++++++  +S A IK+       + L   L LE+     VGW  
Sbjct  180  RVVPLANLEQETRKLAEKIAKKSPISLALIKEVVNRGLDSPLLSGLALES-----VGWGV  234

Query  346  ---SEDYKRGVQAFFDGTTAQFTGQ  367
               +ED K GV AF +     F G+
Sbjct  235  VFSTEDKKEGVSAFLEKREPTFKGK  259


>P9WNN9 Probable enoyl-CoA hydratase EchA8 [Mycobacterium tuberculosis 
(strain ATCC 25618 / H37Rv)]
Length=257

 Score = 123 bits (309),  Expect = 2e-36
 Identities = 77/254 (30%), Positives = 120/254 (47%), Gaps = 4/254 (2%)

Query  112  VVVRQEHGYTVITLNRPEKLNALTRPMLQALKDAVLAATQDHACRAILITGNGRGFCTGQ  171
            ++V ++    +ITLNRP+ LNAL   ++  +  A      D    AI+ITG+ + F  G 
Sbjct  6    ILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELDDDPDIGAIIITGSAKAFAAGA  65

Query  172  DLNERRDLEQAVDLGESLIQFYNPIITAIDQANKPVVCAVNGVAAGAGVGLALACDIVLA  231
            D+ E  DL  A          +  +         P + AV G A G G  LA+ CD+++A
Sbjct  66   DIKEMADLTFADAFTADFFATWGKLAAV----RTPTIAAVAGYALGGGCELAMMCDVLIA  121

Query  232  ADDARFIQSFSKIGLAPDAGISWHLPRLIGSARTKALTILAEPISAVQAQEWGMIWATLP  291
            AD A+F Q   K+G+ P  G S  L R IG A+   L +    + A +A+  G++   +P
Sbjct  122  ADTAKFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVP  181

Query  292  SEKLHSEAEALVKQLSQRPTLSFAAIKQAHRSTAINTLQQQLDLEATLQQKVGWSEDYKR  351
            ++ L +EA A    +SQ    +    K+A      ++L + L  E  L      +ED   
Sbjct  182  ADDLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAFATEDQSE  241

Query  352  GVQAFFDGTTAQFT  365
            G+ AF +    QFT
Sbjct  242  GMAAFIEKRAPQFT  255


>P9WNN8 Probable enoyl-CoA hydratase echA8 [Mycobacterium tuberculosis 
(strain CDC 1551 / Oshkosh)]
Length=257

 Score = 123 bits (309),  Expect = 2e-36
 Identities = 77/254 (30%), Positives = 120/254 (47%), Gaps = 4/254 (2%)

Query  112  VVVRQEHGYTVITLNRPEKLNALTRPMLQALKDAVLAATQDHACRAILITGNGRGFCTGQ  171
            ++V ++    +ITLNRP+ LNAL   ++  +  A      D    AI+ITG+ + F  G 
Sbjct  6    ILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELDDDPDIGAIIITGSAKAFAAGA  65

Query  172  DLNERRDLEQAVDLGESLIQFYNPIITAIDQANKPVVCAVNGVAAGAGVGLALACDIVLA  231
            D+ E  DL  A          +  +         P + AV G A G G  LA+ CD+++A
Sbjct  66   DIKEMADLTFADAFTADFFATWGKLAAV----RTPTIAAVAGYALGGGCELAMMCDVLIA  121

Query  232  ADDARFIQSFSKIGLAPDAGISWHLPRLIGSARTKALTILAEPISAVQAQEWGMIWATLP  291
            AD A+F Q   K+G+ P  G S  L R IG A+   L +    + A +A+  G++   +P
Sbjct  122  ADTAKFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVP  181

Query  292  SEKLHSEAEALVKQLSQRPTLSFAAIKQAHRSTAINTLQQQLDLEATLQQKVGWSEDYKR  351
            ++ L +EA A    +SQ    +    K+A      ++L + L  E  L      +ED   
Sbjct  182  ADDLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAFATEDQSE  241

Query  352  GVQAFFDGTTAQFT  365
            G+ AF +    QFT
Sbjct  242  GMAAFIEKRAPQFT  255


>P64017 Probable enoyl-CoA hydratase echA8 [Mycobacterium bovis 
(strain ATCC BAA-935 / AF2122/97)]
Length=257

 Score = 123 bits (309),  Expect = 2e-36
 Identities = 77/254 (30%), Positives = 120/254 (47%), Gaps = 4/254 (2%)

Query  112  VVVRQEHGYTVITLNRPEKLNALTRPMLQALKDAVLAATQDHACRAILITGNGRGFCTGQ  171
            ++V ++    +ITLNRP+ LNAL   ++  +  A      D    AI+ITG+ + F  G 
Sbjct  6    ILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELDDDPDIGAIIITGSAKAFAAGA  65

Query  172  DLNERRDLEQAVDLGESLIQFYNPIITAIDQANKPVVCAVNGVAAGAGVGLALACDIVLA  231
            D+ E  DL  A          +  +         P + AV G A G G  LA+ CD+++A
Sbjct  66   DIKEMADLTFADAFTADFFATWGKLAAV----RTPTIAAVAGYALGGGCELAMMCDVLIA  121

Query  232  ADDARFIQSFSKIGLAPDAGISWHLPRLIGSARTKALTILAEPISAVQAQEWGMIWATLP  291
            AD A+F Q   K+G+ P  G S  L R IG A+   L +    + A +A+  G++   +P
Sbjct  122  ADTAKFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVP  181

Query  292  SEKLHSEAEALVKQLSQRPTLSFAAIKQAHRSTAINTLQQQLDLEATLQQKVGWSEDYKR  351
            ++ L +EA A    +SQ    +    K+A      ++L + L  E  L      +ED   
Sbjct  182  ADDLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAFATEDQSE  241

Query  352  GVQAFFDGTTAQFT  365
            G+ AF +    QFT
Sbjct  242  GMAAFIEKRAPQFT  255


>P34559 Probable enoyl-CoA hydratase, mitochondrial [Caenorhabditis 
elegans]
Length=288

 Score = 123 bits (308),  Expect = 5e-36
 Identities = 82/268 (31%), Positives = 132/268 (49%), Gaps = 9/268 (3%)

Query  97   ASNLPELNQVPEQSLVVVRQEHGYTVITLNRPEKLNALTRPMLQALKDAVLAATQDHACR  156
            +S  PE+ ++ +     V ++    +I LNRP+ LNAL   ++  L DA+     D +  
Sbjct  27   SSKAPEMIKIEK-----VGEKQNVALIKLNRPKALNALCAQLMTELADALEVLDTDKSVG  81

Query  157  AILITGNGRGFCTGQDLNERRDLEQAVDLGESLIQFYNPIITAIDQANKPVVCAVNGVAA  216
            AI+ITG+ R F  G D+ E  + E A     S +  +    TA+    KPV+ AVNG A 
Sbjct  82   AIVITGSERAFAAGADIKEMTNNEFATTFSGSFLSNW----TAVSDVKKPVIAAVNGFAL  137

Query  217  GAGVGLALACDIVLAADDARFIQSFSKIGLAPDAGISWHLPRLIGSARTKALTILAEPIS  276
            G G  LA+ CDI+ A + ARF Q    IG  P AG +    R  G +    + +    ++
Sbjct  138  GGGNELAMMCDIIYAGEKARFGQPEINIGTIPGAGGTQRWARAAGKSFAMEVCLTGNHVT  197

Query  277  AVQAQEWGMIWATLPSEKLHSEAEALVKQLSQRPTLSFAAIKQAHRSTAINTLQQQLDLE  336
            A +A+E G++    P++++  EA  L ++++ +  L     K+A       TLQ+ L  E
Sbjct  198  AQEAKEHGIVSKIFPADQVVGEAVKLGEKIADQSPLIVQMAKEAVNKAYELTLQEGLHFE  257

Query  337  ATLQQKVGWSEDYKRGVQAFFDGTTAQF  364
              L      ++D K G+ AF +    Q+
Sbjct  258  RRLFHATFATKDRKEGMTAFAEKRKPQW  285


>Q1ZXF1 Probable enoyl-CoA hydratase, mitochondrial [Dictyostelium 
discoideum]
Length=277

 Score = 122 bits (307),  Expect = 5e-36
 Identities = 76/274 (28%), Positives = 138/274 (50%), Gaps = 4/274 (1%)

Query  88   IKAHIQWQSASNLPELNQVPEQSLVVVRQEHGYTVITLNRPEKLNALTRPMLQALKDAVL  147
            +K  I+  S+S  P+     +       ++    ++TLNRP+ LNAL+  ++  +  AV 
Sbjct  2    LKQVIKTVSSSQAPKKYFFKQFCTSTTEKKGRVGLVTLNRPKSLNALSDGLISEINSAVK  61

Query  148  AATQDHACRAILITGNGRGFCTGQDLNERRDLEQAVDLGESLIQFYNPIITAIDQANKPV  207
               +D    +I+ITG+ + F  G D+ E   +         L+  ++ +     +  KP+
Sbjct  62   LFQEDKDVGSIIITGSEKAFAAGADIKEMEKVTLPDAYNNDLLAQWHDLT----KIRKPI  117

Query  208  VCAVNGVAAGAGVGLALACDIVLAADDARFIQSFSKIGLAPDAGISWHLPRLIGSARTKA  267
            + AVNG A G G  LA+ CDI++A + A F Q   K+G  P  G +  L R IG ++   
Sbjct  118  IAAVNGYALGGGCELAMMCDIIIAGEKAVFGQPEIKLGTIPGCGGTQRLIRAIGKSKAME  177

Query  268  LTILAEPISAVQAQEWGMIWATLPSEKLHSEAEALVKQLSQRPTLSFAAIKQAHRSTAIN  327
            L +    ++AV+A++ G++   +P E+L +EA  + ++++    L+ A  K+A  ++   
Sbjct  178  LVLTGNNLTAVEAEKAGLVSKVVPVEELLTEATKMAEKIASYSQLTVAMAKEAVNASYEL  237

Query  328  TLQQQLDLEATLQQKVGWSEDYKRGVQAFFDGTT  361
            TLQ+ +  E  +      + D K G+ AF +  T
Sbjct  238  TLQEGIRFERRMFHSTFGTHDQKEGMNAFVEKRT  271


>O07533 Putative enoyl-CoA hydratase/isomerase YhaR [Bacillus 
subtilis (strain 168)]
Length=255

 Score = 119 bits (297),  Expect = 9e-35
 Identities = 77/242 (32%), Positives = 124/242 (51%), Gaps = 3/242 (1%)

Query  123  ITLNRPEKLNALTRPMLQALKDAVLAATQDHACRAILITGNGRGFCTGQDLNERRDLEQA  182
            I LNRP+  +AL   ML  LK+AV  A    A   +L+ G+G+GF  G D+      E  
Sbjct  15   IILNRPDAHHALNEQMLSELKEAVEMAAASEAL-IVLLRGSGKGFSAGGDIRMMTS-EHD  72

Query  183  VDLGESLIQFYNPIITAIDQANKPVVCAVNGVAAGAGVGLALACDIVLAADDARFIQSFS  242
             D  + L+     +   + Q  K  + A++G AAG G+ LAL  DIVLA  +A    +F 
Sbjct  73   PDQFKRLMDTIEAVTLNLYQMKKVTIAAIHGAAAGLGLSLALCADIVLAEKNAVLAMNFI  132

Query  243  KIGLAPDAGISWHLPRLIGSARTKALTILAEPISAVQAQEWGMIWATLPSEKLHSEAEAL  302
             IGL PD G  + L + IG A+ K L    + +SA +A + G++  T   +     A  +
Sbjct  133  GIGLVPDGGGHYLLKKRIGEAKAKKLIWSGKKLSASEAADMGLLDGTFAGDPAEG-ARPI  191

Query  303  VKQLSQRPTLSFAAIKQAHRSTAINTLQQQLDLEATLQQKVGWSEDYKRGVQAFFDGTTA  362
            ++ L   P L+    K   +S  I  L++ L LE + Q+++  ++D++ G++AF +    
Sbjct  192  IETLLASPLLAMIETKGIFQSLQIEELKKVLSLERSAQERMRRTKDHQEGIRAFLEKREP  251

Query  363  QF  364
            +F
Sbjct  252  KF  253


>Q0AVM1 Crotonyl-CoA hydratase [Syntrophomonas wolfei subsp. wolfei 
(strain DSM 2245B / Goettingen)]
Length=260

 Score = 117 bits (294),  Expect = 3e-34
 Identities = 76/256 (30%), Positives = 127/256 (50%), Gaps = 7/256 (3%)

Query  112  VVVRQEHGYTVITLNRPEKLNALTRPMLQALKDAVLAATQDHACRAILITGNG-RGFCTG  170
            +++ +E    V+ +NRP+ +NAL +  L  +KDAV A   D A   ++ITG+G + F  G
Sbjct  6    IILEKEEKLAVLYINRPKAMNALNKDTLLEIKDAVTAVNDDPAVELLIITGSGDKSFVAG  65

Query  171  QDLNERRDLE--QAVDLGESLIQFYNPIITAIDQANKPVVCAVNGVAAGAGVGLALACDI  228
             D+   ++L   +A + G         +   I+   KPV+ AVNG A G G  LA+ CD 
Sbjct  66   ADIAFMQNLSAMEAREFGA----LGQKVFRLIEAMEKPVIAAVNGFALGGGCELAMCCDF  121

Query  229  VLAADDARFIQSFSKIGLAPDAGISWHLPRLIGSARTKALTILAEPISAVQAQEWGMIWA  288
             +AA +A+F Q    +G+ P  G +  LPRL+G    K L   A+ I+A +A   G++  
Sbjct  122  RIAASNAKFGQPEVGLGITPGFGGTQRLPRLVGPGMAKQLLYTADVINADEAFRIGLVNK  181

Query  289  TLPSEKLHSEAEALVKQLSQRPTLSFAAIKQAHRSTAINTLQQQLDLEATLQQKVGWSED  348
             +  E+L  E + +  ++  +  L+    K A        + + + +EA        ++D
Sbjct  182  VVQPEELLPEVKKIAGRILSKGQLAVRLSKAAANEGMQTDIDRAMSIEADAFGLCFATQD  241

Query  349  YKRGVQAFFDGTTAQF  364
             K G+ AF +   A F
Sbjct  242  QKEGMTAFLEKRKANF  257


>P30084 Enoyl-CoA hydratase, mitochondrial [Homo sapiens]
Length=290

 Score = 117 bits (294),  Expect = 5e-34
 Identities = 75/246 (30%), Positives = 120/246 (49%), Gaps = 4/246 (2%)

Query  122  VITLNRPEKLNALTRPMLQALKDAVLAATQDHACRAILITGNGRGFCTGQDLNERRDLEQ  181
            +I LNRP+ LNAL   ++  L  A+    +D A  AI++TG  + F  G D+ E ++L  
Sbjct  49   LIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSF  108

Query  182  AVDLGESLIQFYNPIITAIDQANKPVVCAVNGVAAGAGVGLALACDIVLAADDARFIQSF  241
                    ++ ++ +     Q  KPV+ AVNG A G G  LA+ CDI+ A + A+F Q  
Sbjct  109  QDCYSSKFLKHWDHLT----QVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPE  164

Query  242  SKIGLAPDAGISWHLPRLIGSARTKALTILAEPISAVQAQEWGMIWATLPSEKLHSEAEA  301
              IG  P AG +  L R +G +    + +  + ISA  A++ G++    P E L  EA  
Sbjct  165  ILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQ  224

Query  302  LVKQLSQRPTLSFAAIKQAHRSTAINTLQQQLDLEATLQQKVGWSEDYKRGVQAFFDGTT  361
              ++++    +  A  K++  +    TL +   LE  L      ++D K G+ AF +   
Sbjct  225  CAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRK  284

Query  362  AQFTGQ  367
            A F  Q
Sbjct  285  ANFKDQ  290


>Q52995 Probable enoyl-CoA hydratase [Rhizobium meliloti (strain 
1021)]
Length=257

 Score = 113 bits (282),  Expect = 1e-32
 Identities = 72/243 (30%), Positives = 122/243 (50%), Gaps = 4/243 (2%)

Query  122  VITLNRPEKLNALTRPMLQALKDAVLAATQDHACRAILITGNGRGFCTGQDLNERRDLEQ  181
            +ITLNRP+ LNAL   +++ L  A+ A   D A  AI++ G+ + F  G D+ E     Q
Sbjct  16   LITLNRPQALNALNAVLMRELDAALKAFDADRAVGAIVLAGSEKAFAAGADIKEM----Q  71

Query  182  AVDLGESLIQFYNPIITAIDQANKPVVCAVNGVAAGAGVGLALACDIVLAADDARFIQSF  241
             +D  +  +  +      +  A KP++ AV+G A G G  LA+ CD ++A++ A+F Q  
Sbjct  72   GLDFVDGYLADFLGGWEHVANARKPMIAAVSGFALGGGCELAMMCDFIIASETAKFGQPE  131

Query  242  SKIGLAPDAGISWHLPRLIGSARTKALTILAEPISAVQAQEWGMIWATLPSEKLHSEAEA  301
              +G+ P  G S  L R +G A+   L +    + A +A+  G++   +  ++L  EA  
Sbjct  132  ITLGVIPGMGGSQRLTRAVGKAKAMDLILTGRMMDAAEAERSGLVSRVVAPDRLLEEALG  191

Query  302  LVKQLSQRPTLSFAAIKQAHRSTAINTLQQQLDLEATLQQKVGWSEDYKRGVQAFFDGTT  361
              ++++     +    K+A   +   TL + L  E  L Q +  +ED K G+ AF     
Sbjct  192  AAEKIASFSLPAAMMAKEAVNRSLELTLAEGLRFERRLFQSLFATEDQKEGMAAFVAKRK  251

Query  362  AQF  364
            A+F
Sbjct  252  AEF  254


>O34893 Putative enoyl-CoA hydratase/isomerase YngF [Bacillus 
subtilis (strain 168)]
Length=260

 Score = 112 bits (280),  Expect = 3e-32
 Identities = 83/258 (32%), Positives = 128/258 (50%), Gaps = 6/258 (2%)

Query  111  LVVVRQEHGYTVITLNRPEKLNALTRPMLQALKDAVLAATQDHACRAILITGNG-RGFCT  169
            L  V+ EH   +ITLNRP+  NAL+  ML+ L+  +     +   R +++TG G + FC 
Sbjct  6    LFTVKNEH-MALITLNRPQAANALSAEMLRNLQMIIQEIEFNSNIRCVILTGTGEKAFCA  64

Query  170  GQDLNERRDL-EQAVDLGESLIQFYNPIITAIDQANKPVVCAVNGVAAGAGVGLALACDI  228
            G DL ER  L E  V    SLIQ    ++ A+ Q   PV+ A+NG A G G+ LALACD+
Sbjct  65   GADLKERIKLKEDQVLESVSLIQRTAALLDALPQ---PVIAAINGSALGGGLELALACDL  121

Query  229  VLAADDARFIQSFSKIGLAPDAGISWHLPRLIGSARTKALTILAEPISAVQAQEWGMIWA  288
             +A + A      + + + P AG +  LPRLIG  + K        ++A +A+E G++  
Sbjct  122  RIATEAAVLGLPETGLAIIPGAGGTQRLPRLIGRGKAKEFIYTGRRVTAHEAKEIGLVEH  181

Query  289  TLPSEKLHSEAEALVKQLSQRPTLSFAAIKQAHRSTAINTLQQQLDLEATLQQKVGWSED  348
                  L  +AE L   +S    ++    K A        L   L +E    ++   ++D
Sbjct  182  VTAPCDLMPKAEELAAAISANGPIAVRQAKFAINKGLETDLATGLAIEQKAYEQTIPTKD  241

Query  349  YKRGVQAFFDGTTAQFTG  366
             + G+QAF +   A + G
Sbjct  242  RREGLQAFQEKRRAVYKG  259



Lambda      K        H        a         alpha
   0.320    0.133    0.399    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 1120238


  Database: a73f68e6326022f0d85c1d70d8970963.SwissProt.fasta
    Posted date:  May 19, 2024  12:22 AM
  Number of letters in database: 4,215
  Number of sequences in database:  16



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40