BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 1a17546fec37c8629ae1dd79f71bed6e.SwissProt.fasta
5 sequences; 2,084 total letters
Query= ACIAD1974
Length=419
Score E
Sequences producing significant alignments: (Bits) Value
P71778 Esterase/beta-lactamase LipL [Mycobacterium tuberculosis (... 181 3e-56
Q09621 Beta-lactamase domain-containing protein 2 [Caenorhabditis... 112 7e-31
O69773 Beta-lactamase [Providencia stuartii] 49.7 3e-10
Q9KX40 Esterase EstB [Burkholderia gladioli] 48.1 9e-10
P15555 D-alanyl-D-alanine carboxypeptidase [Streptomyces sp. (str... 40.8 2e-07
>P71778 Esterase/beta-lactamase LipL [Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv)]
Length=429
Score = 181 bits (458), Expect = 3e-56
Identities = 125/388 (32%), Positives = 196/388 (51%), Gaps = 47/388 (12%)
Query 13 RNYHGSVDERFIDLAEQFSRLQDARTEQGGAVLVVYFQGQKVLDIFTG--KKSETEQWND 70
R G+ D RF + F+ + R GGA L VY GQ V+D++ G ++ W+
Sbjct 22 RRVFGAADPRFACVVRAFASMFPGRRFGGGA-LAVYLDGQPVVDVWKGWADRAGWVPWSA 80
Query 71 QTLSVCYSTGKGVLATLAHILVSDGLIEYDVPIAHYWPEFAQHQKQKMTLRHILSHQSGL 130
+ + +S KG+ AT+ H L GLI+Y+ P+A YWP F + K +T+R ++ HQ+GL
Sbjct 81 DSAPMVFSATKGMTATVIHRLADRGLIDYEAPVAEYWPAFGANGKATLTVRDVMRHQAGL 140
Query 131 YDIRNIIKDAREMLDWQHMLEVFETTSPRFDIGQSNAYQALTFGWLVGGVLEKATGRHLS 190
+R + +++LD M E P +G+S AY ALTFGWL+ G+ TG+ +
Sbjct 141 SGLRGATQ--QDLLDHVVMEERLAAAVPGRLLGKS-AYHALTFGWLMSGLARAVTGKDMR 197
Query 191 ELMQTYLVQPLQLDGAYFGVPSSEL-SRVARLITTRN-EAKADQQQPKAKKTHQPS---- 244
L + L +PL DG + G P ++ +RVA +I ++ A A + H+ S
Sbjct 198 LLFREELAEPLDTDGLHLGRPPADAPTRVAEIIMPQDIAANAVLTCAMRRLAHRFSGGFR 257
Query 245 ---FKDKLIAWTGQDPQDFQDAMIPKGMRNFSFFSDEGLQAVIPAANGVFTANSLSKIYA 301
F + A G+ P L A IPAANGV TA +L+++Y
Sbjct 258 SMYFPGAIAAVQGEAPL---------------------LDAEIPAANGVATARALARMYG 296
Query 302 MLAKQGQWNGKVIIKPEIFQELSKIQSFSRDKVMP-----IPMHWRLGYHRIITLGKRAK 356
+A G+ +G + E+ L++ +R +V+P +P+++ LGYH + +G
Sbjct 297 AIANGGEIDGIRFLSRELVTGLTR----NRRQVLPDRNLLVPLNFHLGYHG-MPIG-NVM 350
Query 357 HGFGHIGYNGSGAWCDPERDLSFAYTHN 384
GFGH+G GS W DPE ++FA HN
Sbjct 351 PGFGHVGLGGSIGWTDPETGVAFALVHN 378
>Q09621 Beta-lactamase domain-containing protein 2 [Caenorhabditis
elegans]
Length=473
Score = 112 bits (280), Expect = 7e-31
Identities = 101/374 (27%), Positives = 176/374 (47%), Gaps = 35/374 (9%)
Query 39 EQGGAVLVVYFQGQKVLDIFTG--KKSETEQWNDQTLSVCYSTGKGVLATLAHILVSDGL 96
E+ GA + VY + + ++D+ G K+ +W T +V +ST K V A +LV G
Sbjct 88 EREGASITVYHKDRVIVDLQGGYADKASGRKWTPDTRTVVFSTTKAVGAVCVAMLVDRGH 147
Query 97 IEYDVPIAHYWPEFAQHQKQKMTLRHILSHQSGL--YDIRNIIKDAREMLDWQHMLEVFE 154
I YD ++ WPEFAQ+ K+ +T+ ++SH++GL D+ I+DA D++ M EV
Sbjct 148 ISYDDKMSKIWPEFAQNGKENITIDWLMSHRAGLAALDMPITIEDAN---DFEKMSEVIA 204
Query 155 TTSPRFDIGQSNAYQALTFGWLVGGVLEKA--TGRHLSELMQTYLVQPLQLDGAYFGVPS 212
+ P ++ G + Y A+T+GW+V ++ ++ GR + + + +D + G+P
Sbjct 205 SQKPNWEPGTKSGYHAITYGWIVDQIVRRSDPKGRSVGRFFKEEVADVHGID-FHIGLPP 263
Query 213 SELSRVARLITTRNEAKADQQQPKAKKTHQPSFKDKLIAWTGQDPQDFQDAMIP-----K 267
SE V+RL + + H P L + + P + K
Sbjct 264 SEEHTVSRL------SMPSTLHLVREIVHDPRVLIVLAVFNLRPPNSIARKIAANPTWFK 317
Query 268 GMRNFSFFSDEGLQAVIP-AANGVFTANSLSKIYAMLAKQGQWNGKVIIKPEIFQELSKI 326
++ + F++ L A+ AA G+ + L+++++ L +QG+ + E+ ++
Sbjct 318 LEQDVNTFNNPTLHAMEQVAALGITKSRDLARLFS-LVQQGK-----LFSTELLEKFRAP 371
Query 327 QSFSRDKVM--PIPMHWRLGYHRIITLGKRAKHGFGHIGYNGSGAWCDPERDLSFAYTHN 384
Q D+V+ P+P Y R GK K GH GY GS D E ++ AY N
Sbjct 372 QVQGIDEVVMTPLPKGHGFLYERHPMGGK--KWLVGHPGYGGSTVMMDLEDGITIAYVSN 429
Query 385 ---FQIGSITGDYR 395
+G +T YR
Sbjct 430 GLKTGMGELTRTYR 443
>O69773 Beta-lactamase [Providencia stuartii]
Length=384
Score = 49.7 bits (117), Expect = 3e-10
Identities = 40/160 (25%), Positives = 73/160 (46%), Gaps = 8/160 (5%)
Query 69 NDQTLSVCYSTGKGVLATLAHILVSDGLIEYDVPIAHYWPEFAQHQKQKMTLRHILSHQS 128
+D+TL S K ATLA G +++ ++HY PE +++ ++ +H S
Sbjct 78 SDRTLYEIGSLSKTFTATLATYAQIQGKLDFSQSVSHYLPELKGSAFDNVSVMNLATHTS 137
Query 129 GL-YDIRNIIKDAREMLDWQHMLEVFETTSPRFDIGQSNAYQALTFGWLVGGVLEKATGR 187
GL + + IK +++ + ++ P ++GQ +Y L G L+G V K
Sbjct 138 GLSLFVPSDIKTNDQLMAY------YQKWLPDNEVGQYRSYSNLGVG-LLGIVTAKQLNM 190
Query 188 HLSELMQTYLVQPLQLDGAYFGVPSSELSRVARLITTRNE 227
S+ M+ ++ L L Y VP S+ A+ +N+
Sbjct 191 PFSQAMEKLMLPSLGLKHTYIHVPKSQEKYYAQGYNKQNQ 230
>Q9KX40 Esterase EstB [Burkholderia gladioli]
Length=392
Score = 48.1 bits (113), Expect = 9e-10
Identities = 48/189 (25%), Positives = 81/189 (43%), Gaps = 23/189 (12%)
Query 46 VVYFQGQKVLDIFTGKKSETEQWNDQTLSVCYSTGKGVLATLAHILVSDGLIEYDVPIAH 105
++Y + Q + D G+ + TL S K ++A LV+ G + D P+
Sbjct 48 ILYRRAQGLADREAGRPMR-----EDTLFRLASVTKPIVALAVLRLVARGELALDAPVTR 102
Query 106 YWPEF----AQHQKQKMTLRHILSHQSGL-----------YDIRNIIKDAREMLDWQHML 150
+ PEF A + +T+ H+L+H SGL YD R I D ++ D+
Sbjct 103 WLPEFRPRLADGSEPLVTIHHLLTHTSGLGYWLLEGAGSVYD-RLGISDGIDLRDFDLDE 161
Query 151 EVFETTSPRFDIGQSNAYQALTFGWLVGGVLEKATGRHLSELMQTYLVQPLQLDGAYFGV 210
+ S + +Q ++G V+E+ATG+ L+ + + QPL + G
Sbjct 162 NLRRLASAPLSFAPGSGWQYSLALDVLGAVVERATGQPLAAAVDALVAQPLGMRDC--GF 219
Query 211 PSSELSRVA 219
S+E R A
Sbjct 220 VSAEPERFA 228
Score = 22.3 bits (46), Expect = 0.12
Identities = 14/39 (36%), Positives = 20/39 (51%), Gaps = 2/39 (5%)
Query 253 TGQDPQDFQDAMI--PKGMRNFSFFSDEGLQAVIPAANG 289
TGQ DA++ P GMR+ F S E + +P +G
Sbjct 196 TGQPLAAAVDALVAQPLGMRDCGFVSAEPERFAVPYHDG 234
>P15555 D-alanyl-D-alanine carboxypeptidase [Streptomyces sp.
(strain R61)]
Length=406
Score = 40.8 bits (94), Expect = 2e-07
Identities = 33/145 (23%), Positives = 62/145 (43%), Gaps = 12/145 (8%)
Query 78 STGKGVLATLAHILVSDGLIEYDVPIAHYWPEFAQHQKQKMTLRHILSHQSGLYDIRNII 137
S K A + LV +G ++ D + Y P + +T+R ++SH+SGLYD N +
Sbjct 93 SVTKSFSAVVLLQLVDEGKLDLDASVNTYLPGLLPDDR--ITVRQVMSHRSGLYDYTNDM 150
Query 138 ---------KDAREMLDWQHMLEVFETTSPRFDIGQSNAYQALTFGWLVGGVLEKATGRH 188
++ +Q ++ + G + +Y F + G ++EK TG
Sbjct 151 FAQTVPGFESVRNKVFSYQDLITLSLKHGVTNAPGAAYSYSNTNF-VVAGMLIEKLTGHS 209
Query 189 LSELMQTYLVQPLQLDGAYFGVPSS 213
++ Q + PL L ++ P +
Sbjct 210 VATEYQNRIFTPLNLTDTFYVHPDT 234
Score = 16.9 bits (32), Expect = 5.9
Identities = 7/11 (64%), Positives = 8/11 (73%), Gaps = 0/11 (0%)
Query 277 DEGLQAVIPAA 287
D GLQAV+ A
Sbjct 39 DTGLQAVLHTA 49
Lambda K H a alpha
0.322 0.137 0.423 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 702744
Database: 1a17546fec37c8629ae1dd79f71bed6e.SwissProt.fasta
Posted date: May 19, 2024 11:07 PM
Number of letters in database: 2,084
Number of sequences in database: 5
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
