BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 0467271e3a8efed2b525bf3beada3bda.SwissProt.fasta
18 sequences; 7,300 total letters
Query= ACIAD2042
Length=491
Score E
Sequences producing significant alignments: (Bits) Value
Q83CM5 ADP-dependent (S)-NAD(P)H-hydrate dehydratase / NAD(P)H-hy... 245 1e-78
Q9KMX5 ADP-dependent (S)-NAD(P)H-hydrate dehydratase / NAD(P)H-hy... 245 1e-78
A4H7T9 ADP-dependent (S)-NAD(P)H-hydrate dehydratase / NAD(P)H-hy... 232 4e-73
P31806 ADP-dependent (S)-NAD(P)H-hydrate dehydratase / NAD(P)H-hy... 229 3e-72
Q4QFL5 ADP-dependent (S)-NAD(P)H-hydrate dehydratase / NAD(P)H-hy... 219 3e-68
A4HW65 ADP-dependent (S)-NAD(P)H-hydrate dehydratase / NAD(P)H-hy... 212 2e-65
Q2RGI2 ADP-dependent (S)-NAD(P)H-hydrate dehydratase / NAD(P)H-hy... 187 2e-56
O27324 ADP-dependent (S)-NAD(P)H-hydrate dehydratase / NAD(P)H-hy... 181 3e-54
B5YIM0 ADP-dependent (S)-NAD(P)H-hydrate dehydratase / NAD(P)H-hy... 179 2e-53
Q9X024 ADP-dependent (S)-NAD(P)H-hydrate dehydratase / NAD(P)H-hy... 173 2e-51
P96051 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [Streptococc... 105 1e-28
F4FTW6 NAD(P)H-hydrate epimerase [Lentilactobacillus buchneri (st... 88.6 2e-23
D5TAM8 NAD(P)H-hydrate epimerase [Legionella pneumophila serogrou... 73.6 9e-18
P94368 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [Bacillus su... 72.0 3e-17
B3L9G8 NAD(P)H-hydrate epimerase [Plasmodium knowlesi (strain H)] 67.0 2e-15
F8HWV7 NAD(P)H-hydrate epimerase [Leuconostoc sp. (strain C2)] 65.1 4e-15
F4LHM0 NAD(P)H-hydrate epimerase [Bordetella pertussis (strain CS)] 59.7 3e-13
Q6QRN6 NAD(P)H-hydrate epimerase [Bos taurus] 58.2 2e-12
>Q83CM5 ADP-dependent (S)-NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate
epimerase [Coxiella burnetii (strain RSA 493 / Nine
Mile phase I)]
Length=488
Score = 245 bits (625), Expect = 1e-78
Identities = 176/502 (35%), Positives = 265/502 (53%), Gaps = 36/502 (7%)
Query 5 VYHSTQIQAWEQRWFEQQNSSLGLMQQAAWAISQKLHHHILKNSLSIKKIAVWCGSGKNA 64
+Y + QI+ E+ E S LM +A A + L L ++I V CG G N
Sbjct 4 LYQNRQIRELERLAVESGISEYELMCRAGEAAFKAL----LARWPEAQEITVCCGKGNNG 59
Query 65 GDGYYIAIYLKSLGYNISIFTMPAGQSTDLKQAVADA----HANQLPISNHFD-VNNDYD 119
GDG +A G ++++ AGQ LK A A A A+ LPI + + +
Sbjct 60 GDGLVLARLAYENGLKVTVYL--AGQRHQLKGAAAQAANACEASNLPILPFPEPLLFKGE 117
Query 120 CHIDALFGIGLNRELDQNWQSIVHHFNRLSGFKVAVDLPSGLNANTGASLPVAIKVDVTY 179
+DAL G GL+ E+ + ++ N+ + +A+D+PSG+N ++G A+K ++T
Sbjct 118 VIVDALLGSGLSGEVKAPYDHLIAAINQAGQYVLALDVPSGINVDSGEVQGTAVKANLTV 177
Query 180 TILAEKIGLFTGQATEYVGQLELISLIPKDNMLQAFAYLSTQQVK-------LPIRQSFG 232
T +A K GL+T +A Y G+L + L ++ +A + T+ ++ LP R
Sbjct 178 TFIAPKRGLYTDKAPAYCGELIVDRLGLSESFFRA-VFTDTRLLEWKGVFPLLPKRARDA 236
Query 233 HKGTYGHVLVVGGHKNMGGAVIMAAEAAFHAGAGKVTVICDALHHSAILARAPNIMIKDI 292
HKG+YGHVLV+GG MGGAV MAAEAA GAG VTV H + P +M +
Sbjct 237 HKGSYGHVLVIGGDYGMGGAVRMAAEAAARVGAGLVTVATRPEHVPIVSGPRPELMCHQV 296
Query 293 NQIDAQEIEQILKEIDAVCFGMGLGRDQWAKQTFDVWFQQLHQQQKLHVVLDADALWFLS 352
D +++ +L V G GLG+ WAK + + L VLDAD+L L+
Sbjct 297 AAAD--DLKPLLTAATVVVIGPGLGKSDWAKSLLNKVL-----ETDLPKVLDADSLNLLA 349
Query 353 DQSIKLGQNFYMTPHAGEAARLLDISVAQIEQDRFTAIRQLQQRYNGAWVLKGAGSLSLF 412
+S +++ +TPH GEA+RLL IS ++++DRF AI LQ++Y G VLKG G+L
Sbjct 350 -ESPSQREDWILTPHPGEASRLLGISCNEVQRDRFQAINDLQEKYQGVLVLKGVGTLIKD 408
Query 413 HDK-IMICTAGNAGMGTGGMGDVLAGMIASLKAQFDDQICLSDV----VTLHAQAGDLLA 467
+ +C AGN GM TGGMGD+L+G+I L AQ ++ L+ V +H+ A D A
Sbjct 409 ESQAYYVCPAGNPGMATGGMGDILSGIIGGLVAQ---RLSLASAAQAGVFIHSMAADRAA 465
Query 468 -QNGQRGIQAYDMAKAIYHVVN 488
+ G+RG+ A D+ + +VN
Sbjct 466 EEGGERGLLATDLFPHLRVLVN 487
>Q9KMX5 ADP-dependent (S)-NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate
epimerase [Vibrio cholerae serotype O1 (strain ATCC
39315 / El Tor Inaba N16961)]
Length=494
Score = 245 bits (625), Expect = 1e-78
Identities = 189/520 (36%), Positives = 262/520 (50%), Gaps = 62/520 (12%)
Query 1 MQLPV--YHSTQIQAWEQRWFEQQNSSL-GLMQQAAWAI------SQKLHHHILKNSLSI 51
M LP Y + Q++ EQ ++ L LM++A A+ HH L
Sbjct 5 MPLPTHFYTTQQLKQGEQDAASERGLELFHLMERAGQAVFTIAFAQYPTSHHWL------ 58
Query 52 KKIAVWCGSGKNAGDGYYIAIYLKSLGYNISIFTMPAGQSTDLKQAVADAHA-------- 103
+ CG G N GDGY +A+ + +G +++++ Q D ++ ADAH
Sbjct 59 ----ICCGGGNNGGDGYIVAVLARHMGIDVTVW-----QLGDPEKLPADAHRAYQQWKEL 109
Query 104 NQLPISNHFDVNNDYDCHIDALFGIGLNRELDQNWQSIVHHFNRLSGFKVAVDLPSGLNA 163
+ +V D IDALFGIGL L +V N+ VAVD+PSGL A
Sbjct 110 GGAVYAPQSEVPESTDVIIDALFGIGLKEVLRPQVVPLVELLNQSGKPIVAVDVPSGLCA 169
Query 164 NTGASLPVAIKVDVTYTILAEKIGLFTGQATEYVGQLELISLIPKDNMLQAFAYLSTQQV 223
+TG + IK T +++ K GL TGQA YVG L L + + FA +T +
Sbjct 170 DTGQVMGTCIKAQHTVSLIGLKQGLVTGQARCYVGTLHYAGL----GVEEVFAQHNTPSL 225
Query 224 K----------LPIRQSFGHKGTYGHVLVVGGHKNMGGAVIMAAEAAFHAGAGKVTVICD 273
LP RQ+ HKG G L+VGG++ MGGA+I+ A A +GAG +
Sbjct 226 VSIDGKLRHSLLPPRQACTHKGQNGKALIVGGNEGMGGALILCASACARSGAGLSAAMTH 285
Query 274 ALHHSAILARAPNIMIKDINQIDAQEIEQILKEIDAVCFGMGLGRDQWAKQTFDVWFQQL 333
+ +A+L P +M N+ E+ ++ DA+ G GLGRD A+Q Q
Sbjct 286 PDNVTAMLTITPEVMSTSWNK--QHLFEERIEWCDALALGPGLGRDAQAQQ-----IMQR 338
Query 334 HQQQKLHVVLDADALWFLSDQSIKLGQNFYMTPHAGEAARLLDISVAQIEQDRFTAIRQL 393
K+ V DADAL+FL+ Q +TPH EAARLL V ++EQDRF AIRQL
Sbjct 339 LSSLKVPKVWDADALYFLAHNPSYDAQRI-ITPHPVEAARLLGCEVEEVEQDRFAAIRQL 397
Query 394 QQRYNGAWVLKGAGSLSLFHDKIMICTAGNAGMGTGGMGDVLAGMIASLKAQFDDQICLS 453
QQRY G VLKGAG+L +I +C GN GM +GGMGDVL G+I +L AQ +I L+
Sbjct 398 QQRYGGVVVLKGAGTLVDDGKEIAVCLQGNPGMASGGMGDVLTGIIVALLAQ---KIPLA 454
Query 454 DV----VTLHAQAGDL-LAQNGQRGIQAYDMAKAIYHVVN 488
D V LH+ A DL +GQRG+ A D+ + ++N
Sbjct 455 DAAKLGVWLHSSAADLNTKSHGQRGLLASDLLPHLRELLN 494
>A4H7T9 ADP-dependent (S)-NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate
epimerase [Leishmania braziliensis]
Length=561
Score = 232 bits (592), Expect = 4e-73
Identities = 163/482 (34%), Positives = 239/482 (50%), Gaps = 61/482 (13%)
Query 59 GSGKNAGDGYYIAIYLKSLGYNISIFTMPAGQSTDLKQAVADAHANQLPISNHFDVN--- 115
GSG N GDGY IA + + G +++ +MP + + A HA Q +N
Sbjct 74 GSGNNGGDGYVIARHAREAGRKVTVLSMPHSKPLPTEATNAQ-HAWQAVGGTETMINPGT 132
Query 116 -----NDYDCHIDALFGIGLNRELDQNWQSIVHHFNRLSGFKVAVDLPSGLNANTGASLP 170
D D +D L G G++ ++++ ++ H N L +VA+D+PSGLNA TG +
Sbjct 133 SLHLPTDVDLVVDGLLGTGISGPPREHYEEVIRHINALPVPRVAIDIPSGLNAETGEAAG 192
Query 171 VAIKVDVTYTILAEKIGLFTGQATEYVGQLELISLIPKDNMLQA---------------- 214
+K D T T + K GL TGQA +YVGQL SL ++ M+ A
Sbjct 193 ACVKADHTATFICLKPGLLTGQARDYVGQLHYRSLGLEEWMIAAERMDAALCRRVALGDV 252
Query 215 FAYLSTQQVKLPIRQSFGHKGTYGHVLVVGGHKNMGGAVIMAAEAAFHAGAGKVTVICDA 274
+ Y ST+ R + HKG+ G V+++GG GGA++M+AEA GAG V+
Sbjct 253 YGYFSTR------RSAVAHKGSCGKVVLIGGDHGFGGAILMSAEACLTIGAGLTRVLTRP 306
Query 275 LHHSAILARAPNIMIKDINQIDAQEIEQILKE----IDAVCFGMGLGRDQWAKQTFDVWF 330
+ + +L R P +M+ + + ++EQ + E + G GLG + +
Sbjct 307 EYVAPLLTRCPEVMVTAVETETSGQLEQQMVEAFEWASTLAVGPGLGTGAYGQAALSAAL 366
Query 331 QQLHQQQKLHVVLDADALWFLSDQ--SIKLG------------QNFYMTPHAGEAARLLD 376
QQ Q +VLDADAL L+++ S ++G N +TPH GEAARLL
Sbjct 367 QQAEMHQDKTLVLDADALNLLAERLHSKEMGAAVGAGKYLPVLPNSIITPHPGEAARLLA 426
Query 377 ISVAQIEQDRFTAIRQLQQRYNGAWVLKGAGSL--SLFHDKIMICTAGNAGMGTGGMGDV 434
VA +E+DR A R+L G +LKG G++ K I AGNAGM +GGMGDV
Sbjct 427 CRVADVEKDRLAAARRLAAILGGTCLLKGPGTVVHCQSSGKTAIVDAGNAGMASGGMGDV 486
Query 435 LAGMIASLKAQ-----FDDQICLSDVVTLHAQAGDLLAQ---NGQRGIQAYDMAKAIYHV 486
L G++A L AQ D C + +V H A D++A G RGI+A ++ I +
Sbjct 487 LTGLLAGLAAQRMMHDTFDTTCAAALV--HGVAADMVAAEDGRGTRGIRATELIPRIPFI 544
Query 487 VN 488
VN
Sbjct 545 VN 546
>P31806 ADP-dependent (S)-NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate
epimerase [Escherichia coli (strain K12)]
Length=515
Score = 229 bits (583), Expect = 3e-72
Identities = 162/451 (36%), Positives = 232/451 (51%), Gaps = 34/451 (8%)
Query 56 VWCGSGKNAGDGYYIAIYLKSLGYNISIFTMPAGQSTDLKQAVADAHANQLPISNHFDVN 115
V CG G N GDGY +A K++G +++ + + L + A A L +
Sbjct 65 VLCGHGNNGGDGYVVARLAKAVGIEVTLLAQESDKP--LPEEAALAREAWLNAGGEIHAS 122
Query 116 N-----DYDCHIDALFGIGLNRELDQNWQSIVHHFNRLSGFKVAVDLPSGLNANTGASLP 170
N D +DAL G GL + ++ ++ H N VAVD+PSGL A TGA+
Sbjct 123 NIVWPESVDLIVDALLGTGLRQAPRESISQLIDHANSHPAPIVAVDIPSGLLAETGATPG 182
Query 171 VAIKVDVTYTILAEKIGLFTGQATEYVGQLELIS------LIPKDNMLQAFAYLSTQQVK 224
I D T T +A K GL TG+A + GQL S L ++ +Q F S +Q+
Sbjct 183 AVINADHTITFIALKPGLLTGKARDVTGQLHFDSLGLDSWLAGQETKIQRF---SAEQLS 239
Query 225 --LPIRQSFGHKGTYGHVLVVGGHKNMGGAVIMAAEAAFHAGAGKVTVICDALHHSAILA 282
L R+ HKG +G ++++GG GA+ M EAA AGAG V V+ + + + +L
Sbjct 240 HWLKPRRPTSHKGDHGRLVIIGGDHGTAGAIRMTGEAALRAGAGLVRVLTRSENIAPLLT 299
Query 283 RAPNIMIKDINQIDAQEIEQILKEIDAVCFGMGLGRDQWAKQTFDVWFQQLHQQQKLHVV 342
P +M ++++ + + L+ D V G GLG+ +W K+ Q + + ++
Sbjct 300 ARPELM---VHELTMDSLTESLEWADVVVIGPGLGQQEWGKKAL-----QKVENFRKPML 351
Query 343 LDADALWFLSDQSIKLGQNFYMTPHAGEAARLLDISVAQIEQDRFTAIRQLQQRYNGAWV 402
DADAL L+ K N +TPH GEAARLL SVA+IE DR ++L QRY G V
Sbjct 352 WDADALNLLAINPDK-RHNRVITPHPGEAARLLGCSVAEIESDRLHCAKRLVQRYGGVAV 410
Query 403 LKGAGSLSLFH-DKIMICTAGNAGMGTGGMGDVLAGMIASL---KAQFDDQICLSDVVTL 458
LKGAG++ H D + I AGNAGM +GGMGDVL+G+I +L K D C V
Sbjct 411 LKGAGTVVAAHPDALGIIDAGNAGMASGGMGDVLSGIIGALLGQKLSPYDAACAGCVA-- 468
Query 459 HAQAGDLLAQN-GQRGIQAYDMAKAIYHVVN 488
H A D+LA G RG+ A D+ + +VN
Sbjct 469 HGAAADVLAARFGTRGMLATDLFSTLQRIVN 499
>Q4QFL5 ADP-dependent (S)-NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate
epimerase [Leishmania major]
Length=560
Score = 219 bits (559), Expect = 3e-68
Identities = 165/486 (34%), Positives = 235/486 (48%), Gaps = 52/486 (11%)
Query 50 SIKKIAVWCGSGKNAGDGYYIAIYLKSLGYNISIFTMP--------AGQSTDLKQAVADA 101
S K + GSG N GDGY IA + + G +++ MP A + +AV
Sbjct 65 SQKHWLILVGSGNNGGDGYVIARHAREAGKIVTVLRMPHSKPLPTEAASAQHAWKAVGGT 124
Query 102 HANQLPISNHFDVNNDYDCHIDALFGIGLNRELDQNWQSIVHHFNRLSGFKVAVDLPSGL 161
+ P + D D +D L G G+ + + ++ H N L +VA+D+PSGL
Sbjct 125 ESTMSP-GAPLQLPADVDLIVDGLLGTGICGPPREQYADVIRHINGLPVPRVAIDIPSGL 183
Query 162 NANTGASLPVAIKVDVTYTILAEKIGLFTGQATEYVGQLELISLIPKDNML--QAFAYLS 219
NA TG + +K D T T + K GL TGQA +YVGQL SL +D M +
Sbjct 184 NAETGEAAGACVKADHTATFICLKPGLLTGQAKDYVGQLHYRSLGLEDWMTAPERMRVAL 243
Query 220 TQQVKLP--------IRQSFGHKGTYGHVLVVGGHKNMGGAVIMAAEAAFHAGAGKVTVI 271
++V L R + HKG+ G ++VGG GGA +M+AEA GAG V+
Sbjct 244 CRRVALDDVYEYFGIRRSALAHKGSCGKAILVGGDHGFGGAALMSAEACVTVGAGLTRVL 303
Query 272 CDALHHSAILARAPNIMIKDINQIDAQEIEQILKEID------AVCFGMGLGRDQWAKQT 325
+ + +L R P M+ + ++++Q + E AV G+G G A T
Sbjct 304 TRPEYAAPLLTRCPEAMVTAVETDTGEQLKQQMLEAFEWASTLAVGPGLGTGAYGQAALT 363
Query 326 FDVWFQQLHQQQKLHVVLDADALWFLSD--------------QSIKLGQNFYMTPHAGEA 371
+ +LHQ + L VLDADAL L+ + + + N +TPH GEA
Sbjct 364 AALRHAELHQDKTL--VLDADALNLLAGCLHGREGGAAAGARKHLPVLPNSIITPHPGEA 421
Query 372 ARLLDISVAQIEQDRFTAIRQLQQRYNGAWVLKGAGSLSLFHD--KIMICTAGNAGMGTG 429
ARLLD VA +E+DR A R+L G +LKG G++ H K I AGNAGM +G
Sbjct 422 ARLLDCRVADVEKDRLAAARRLAAILGGTCLLKGPGTIVHCHSSAKTAIVDAGNAGMASG 481
Query 430 GMGDVLAGMIASLKAQ----FDDQICLSDVVTLHAQAGDLLAQ---NGQRGIQAYDMAKA 482
GMGDVL G++A L AQ D C +V H A D++A G RGI+A ++
Sbjct 482 GMGDVLTGLLAGLAAQRMHDTFDTTCAGALV--HGVAADMVAAEDGRGTRGIRATELIHR 539
Query 483 IYHVVN 488
+ +VN
Sbjct 540 VPLIVN 545
>A4HW65 ADP-dependent (S)-NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate
epimerase [Leishmania infantum]
Length=560
Score = 212 bits (540), Expect = 2e-65
Identities = 157/473 (33%), Positives = 224/473 (47%), Gaps = 44/473 (9%)
Query 59 GSGKNAGDGYYIAIYLKSLGYNISIFTMPAGQSTDLKQAVADAHANQLPISNHFDVNN-- 116
GSG N GDGY IA + + G +++ MP + + A A HA + +N
Sbjct 74 GSGNNGGDGYVIARHAREAGKIVTVLCMPHSKPLPAEAASAQ-HAWKAVGGTETTMNPGA 132
Query 117 ------DYDCHIDALFGIGLNRELDQNWQSIVHHFNRLSGFKVAVDLPSGLNANTGASLP 170
D D +D L G G+ + ++ ++ H N L +VA+D+PSGLNA TG
Sbjct 133 PLQLPADVDLIVDGLLGTGICGPPREQYEDVIRHINGLPVPRVAIDIPSGLNAETGEVAG 192
Query 171 VAIKVDVTYTILAEKIGLFTGQATEYVGQLELISLIPKDNML---QAFAYLSTQQVKLPI 227
+K D T T + K GL TGQA +YVGQL SL +D M + A L + +
Sbjct 193 ACVKADHTATFICLKPGLLTGQAKDYVGQLHYRSLGLEDWMTAPERMRAALCRRVALDDV 252
Query 228 RQSFG-------HKGTYGHVLVVGGHKNMGGAVIMAAEAAFHAGAGKVTVICDALHHSAI 280
+ FG HKG G V++VGG GGA +M+AEA GAG V+ + + +
Sbjct 253 YEYFGIRRSALAHKGRCGKVILVGGDHGFGGATLMSAEACVTVGAGLTRVLTRPEYAAPL 312
Query 281 LARAPNIMIKDINQIDAQEIEQ----ILKEIDAVCFGMGLGRDQWAKQTFDVWFQQLHQQ 336
L R P M+ + ++EQ + + G GLG + + +
Sbjct 313 LTRCPEAMVTAVETDTGGQLEQQMLAAFEWASTLAVGPGLGTGAYGQAALTAALRHAEVH 372
Query 337 QKLHVVLDADALWFL--------------SDQSIKLGQNFYMTPHAGEAARLLDISVAQI 382
Q +VLDADAL L + + + + N +TPH GEAARLL VA +
Sbjct 373 QDKTLVLDADALNLLAGRLHGKEGGAAAGAGKHLPVLPNSIITPHPGEAARLLACRVADV 432
Query 383 EQDRFTAIRQLQQRYNGAWVLKGAGSLSLFHD--KIMICTAGNAGMGTGGMGDVLAGMIA 440
E+DR A R+L G +LKG G++ H K I AGNAGM +GGMGDVL G++A
Sbjct 433 EKDRLAAARRLAAILGGTCLLKGPGTIVHCHSSAKTAIVDAGNAGMASGGMGDVLTGLLA 492
Query 441 SLKAQ--FDDQICLSDVVTLHAQAGDLLAQ---NGQRGIQAYDMAKAIYHVVN 488
L AQ D +H A D++A G RGI+A ++ + +VN
Sbjct 493 GLAAQRMHDTFNTTCAGALVHGVAADMVAAEDGRGTRGIRATELIHRVPLIVN 545
>Q2RGI2 ADP-dependent (S)-NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate
epimerase [Moorella thermoacetica (strain ATCC 39073
/ JCM 9320)]
Length=530
Score = 187 bits (475), Expect = 2e-56
Identities = 149/504 (30%), Positives = 237/504 (47%), Gaps = 52/504 (10%)
Query 25 SLGLMQQAAWAISQKLHHHILKNSLSIKKIAVWCGSGKNAGDGYYIAIYLKSLGYNISIF 84
S+ LM+ A + + + H + ++ ++I ++CG G N GDG +A +L + G + +F
Sbjct 24 SIVLMENAGLRVVESIERHF-QGQVANRRILIFCGKGNNGGDGLVVARHLLNRGAEVKVF 82
Query 85 TMPAGQST----------------DLKQAVADAHANQLPISNHFDVNNDYDCHIDALFGI 128
+ + L + ++H + I+ + D +DA+FG
Sbjct 83 LLARPEDIRGDARTNLEIYQKMGGKLLLLLGESHLQRADIALLYA-----DLVVDAIFGT 137
Query 129 GLNRELDQNWQSIVHHFNRLSGFKVAVDLPSGLNANTGASLPVAIKVDVTYTILAEKIGL 188
G ++++ N+ VAVDLPSGL A+TG I+ T T K+GL
Sbjct 138 GFKGAAMGLPAAVINMINKAHRETVAVDLPSGLEADTGRCFGPCIQATWTVTFALPKLGL 197
Query 189 FTGQATEYVGQLELISL-IPK--------DNMLQAFAYLSTQQVKLPIRQSFGHKGTYGH 239
G+LE+ + IP+ + L A+ +Q LP R++ GHKG YG
Sbjct 198 VVEPGASLTGRLEVADIGIPQKLVATQHFNRRLLTAAWCRSQ---LPRREASGHKGLYGR 254
Query 240 VLVVGGHKNMGGAVIMAAEAAFHAGAGKVTVICDALHHSAILARAPNIMIKDINQIDAQE 299
VL VGG + GA+ +AA AA AGAG VT + + IM + + A
Sbjct 255 VLAVGGSPGLTGAITLAATAALKAGAGLVTAAVPRGVQGILAMKTTEIMTMSLPETPAGA 314
Query 300 IE--------QILKEIDAVCFGMGLGRDQWAKQTFDVWFQQLHQQQKLHVVLDADALWFL 351
+ + L E+D + G GL RD T D+ ++L + ++ V+DADAL L
Sbjct 315 LSRDALDPLLERLAEVDVLAIGPGLSRD---PATVDL-VKELLPRVQVPAVVDADALNAL 370
Query 352 -SDQSIKLGQN--FYMTPHAGEAARLLDISVAQIEQDRFTAIRQLQQRYNGAWVLKGAGS 408
+D + G + +TPH GE ARLL + A+I++DR + + + +LKGA +
Sbjct 371 ATDTRVLTGDHGPLVLTPHPGEMARLLGTTAAKIQEDRLEIAAKYAREWQAVLLLKGART 430
Query 409 LSLFHD-KIMICTAGNAGMGTGGMGDVLAGMIASLKAQ-FDDQICLSDVVTLHAQAGDLL 466
+ + D ++ I GN GM T G GDVL G+IA L Q + + LH AGD
Sbjct 431 VIAWPDGQVYINPTGNPGMATAGSGDVLTGIIAGLAGQGLKPGVAAALGAYLHGAAGDEA 490
Query 467 A-QNGQRGIQAYDMAKAIYHVVNH 489
A Q GQR + A D+ + +V+ +
Sbjct 491 ARQRGQRAMMAGDLLDFLPYVLRN 514
>O27324 ADP-dependent (S)-NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate
epimerase [Methanothermobacter thermautotrophicus
(strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta
H)]
Length=519
Score = 181 bits (459), Expect = 3e-54
Identities = 134/488 (27%), Positives = 231/488 (47%), Gaps = 39/488 (8%)
Query 26 LGLMQQAAWAISQKLHHHILKNSLSIKKIAVWCGSGKNAGDGYYIAIYLKSLGYNISIFT 85
L LM+ A A+++++ N++ ++A++CG G N GDG+ A +L ++G+ + +
Sbjct 40 LSLMENAGRAVAEEIG-----NAVDSGRVAIFCGPGGNGGDGFVAARHLLNMGFEVEVHL 94
Query 86 MPAGQSTDLKQAVAD--AHANQLPISNHFDVN----------NDYDCHIDALFGIGLNRE 133
+ + ++A+ + P F V+ D D +DA+ G G+
Sbjct 95 LGHPERIGSEEALVNWGVLGAMQPHPGGFSVDFVRDSSEIKPTDADVVVDAILGTGVRGS 154
Query 134 LDQNWQSIVHHFNRLSGFKVAVDLPSGLNANTGASLPVAIKVDVTYTILAEKIGLFTGQA 193
+ + +S + NR F+V+VD+PSGLN TGA +A+ D+T T K GL
Sbjct 155 IREPSRSAIEIINRSEAFRVSVDIPSGLNPETGAVEDIAVSADLTVTFHRMKDGLKLADP 214
Query 194 TEYVGQLEL--ISLIPKDNMLQAFAYLSTQQVKLPIRQSFGHKGTYGHVLVVGGHKNMGG 251
G++ + I + P + L +++P R+ HKG G VL++GG + G
Sbjct 215 A-VTGEIVVRDIGIPPAAEIFMGPGDL----LRIPSRRPGSHKGENGRVLIIGGSRQYSG 269
Query 252 AVIMAAEAAFHAGAGKVTVICDALHHSAILARAPNIMIKD-----INQIDAQEIEQILKE 306
A +AA+AA AGA V V AI + +P++++++ I EI ++ ++
Sbjct 270 APAIAAKAALRAGADIVMVAAPGSAARAIRSLSPDLIVRELEGGYIGMESLDEILELAEK 329
Query 307 IDAVCFGMGLGRDQWAKQTFDVWFQQLHQQQKLHVVLDADALWFLSDQSIKLGQNFYMTP 366
D+V G G GR+ +TF + LH+ +K +VLDADAL + + + +TP
Sbjct 330 ADSVLMGCGAGRETSTARTFMRAIEDLHEMEK-PIVLDADALRLMDYSDVSEYRELTVTP 388
Query 367 HAGEAARLLDIS--VAQIEQDRFTAIRQLQQRYNGAWVLKGAGSLSLFHDKIMICTAGNA 424
H E + + + ++ +A + + R G +LKG + D++ + G
Sbjct 389 HMAEFSSFFKLKSMIFNDFRESVSAFQSISSRIRGTVLLKGRIDMIFQGDRLRLNKTGCP 448
Query 425 GMGTGGMGDVLAGMIASLKA----QFDDQICLSDVVTLHAQAGDLLAQNGQRGIQAYDMA 480
GM GG GD LAG+ A L+A FD S ++ AG+L + G A DM
Sbjct 449 GMTVGGTGDALAGLTAGLRALGLSSFDS---ASLAAFINGMAGELAMERHGNGFTASDMV 505
Query 481 KAIYHVVN 488
I V++
Sbjct 506 DMIPSVMD 513
>B5YIM0 ADP-dependent (S)-NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate
epimerase [Thermodesulfovibrio yellowstonii (strain
ATCC 51303 / DSM 11347 / YP87)]
Length=514
Score = 179 bits (453), Expect = 2e-53
Identities = 145/481 (30%), Positives = 231/481 (48%), Gaps = 35/481 (7%)
Query 28 LMQQAAWAISQKLHHHILKNSLSIKKIAVWCGSGKNAGDGYYIAIYLKSLGYNISIFTMP 87
LM++AA +I + H+LK + + + + G G N GDG LK+ NI IF +
Sbjct 29 LMERAALSIVK----HVLK--FNPENLIILAGPGNNGGDGIACGRILKNKVKNIKIFQLF 82
Query 88 AGQ--STDLKQAVADAHANQLPISNHFDVNNDYD---CHIDALFGIGLNRELDQNWQSIV 142
+ S D K ++ A +PI + N+ D IDA+FG GL RE++ +
Sbjct 83 PEEKLSEDCKLQLSVAKKFGIPIVVGYPDNDQIDKADLIIDAIFGTGLKREIEGKVAEFI 142
Query 143 HHFNRLSGFKVAVDLPSGLNANTGASLPVAIKVDVTYTILAEKIGLFTGQATEYVGQLEL 202
N VAVD+PSG++++TG L AIK ++T T K G +Y G+L +
Sbjct 143 EILNSFKKLTVAVDIPSGVSSDTGEILGAAIKANLTVTFGLPKRGHLLYPGKDYTGELFI 202
Query 203 ------ISLIPKDNMLQAFAYLSTQQVKLPIRQSFGHKGTYGHVLVVGGHKNMGGAVIMA 256
L +N+ + +P R + HK YGHV V+ G GA +M
Sbjct 203 EDIGFPEELTNNENLKISLIEREFALSLMPPRPKYSHKTRYGHVFVIAGSTGKTGAAMMT 262
Query 257 AEAAFHAGAGKVTVICDALHHSAILARAPNIMIKDI----NQIDAQEIEQIL----KEID 308
A+AA AG+G VT+ A ++ MI + N + Q + +I+ ++ +
Sbjct 263 AKAALRAGSGLVTMAVPAALKVVFQSKVLEEMILPLPCTMNTLSKQALPEIMDFVKEKAN 322
Query 309 AVCFGMGLGRDQWAKQTFDVWFQQLHQQQKLHVVLDADALWFLSDQSIKL---GQNFYMT 365
++ FG G+G + ++ ++L +V+DAD L LS L +T
Sbjct 323 SIAFGPGVG----VNEDIEIILRELILNSSCPIVIDADGLTVLSKILNVLKDAHSEIVLT 378
Query 366 PHAGEAARLLDISVAQIEQDRFTAIRQLQQRYNGAWVLKGAGS-LSLFHDKIMICTAGNA 424
PH GE +RL++I V IE+ R +++ Q N VLKG + ++ ++ + T GN
Sbjct 379 PHPGELSRLINIPVKDIEKQRIDIAQKVAQELNVIIVLKGVPTVIAEPQGRVYLNTTGNP 438
Query 425 GMGTGGMGDVLAGMIASLKAQFDDQICLSDV-VTLHAQAGDLLA-QNGQRGIQAYDMAKA 482
GM TGG GDVL G+IASL Q + S V +H +GD+ + + G G+ A D+ +
Sbjct 439 GMATGGSGDVLTGIIASLIGQGLSPLYASVFGVYIHGLSGDIASRRKGFHGLIAGDIIET 498
Query 483 I 483
+
Sbjct 499 L 499
>Q9X024 ADP-dependent (S)-NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate
epimerase [Thermotoga maritima (strain ATCC 43589
/ DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)]
Length=490
Score = 173 bits (438), Expect = 2e-51
Identities = 128/471 (27%), Positives = 233/471 (49%), Gaps = 23/471 (5%)
Query 28 LMQQAAWAISQKLHHHILKNSLSIKKIAVWCGSGKNAGDGYYIAIYLKSLGYNISIFTMP 87
LM++A ++ + + +LS + V CG G N GDG+ +A L + ++ + +
Sbjct 19 LMERAGISVVLAMEEEL--GNLSDYRFLVLCGGGNNGGDGFVVARNLLGVVKDVLVVFLG 76
Query 88 AGQSTDLKQAVADAHANQLPISNHFD--VNNDYDCHIDALFGIGLNRELDQNWQSIVHHF 145
++ D + + F+ + N++D +DA+FG GL E+ + I++
Sbjct 77 KKKTPDCEYNYGLYKKFGGKVVEQFEPSILNEFDVVVDAIFGTGLRGEITGEYAEIINLV 136
Query 146 NRLSGFKVAVDLPSGLNANTGASLPVAIKVDVTYTILAEKIGLFTGQATEYVGQLELISL 205
N+ V+VD+PSG+++NTG L A+K D+T T KIG + G+L++ ++
Sbjct 137 NKSGKVVVSVDVPSGIDSNTGKVLRTAVKADLTVTFGVPKIGHILFPGRDLTGKLKVANI 196
Query 206 IPKDNMLQAF-AYLSTQQV---KLPIRQSFGHKGTYGHVLVVGGHKNMGGAVIMAAEAAF 261
+++ + Y+ T+++ LP R HKGTYG VL++ G + GA +++ +
Sbjct 197 GHPVHLINSINRYVITREMVRSLLPERPRDSHKGTYGKVLIIAGSRLYSGAPVLSGMGSL 256
Query 262 HAGAGKVTVICDALHHSAILARAPNIMIKDINQ-------IDAQEIEQILKEIDAVCFGM 314
G G V + + +R P ++ I+ + QE ++ K++D V G
Sbjct 257 KVGTGLVKLAVPFPQNLIATSRFPELISVPIDTEKGFFSLQNLQECLELSKDVDVVAIGP 316
Query 315 GLGRDQWAKQTFDVWFQQLHQQQKLHVVLDADALWFLSDQSIKLGQN-FYMTPHAGEAAR 373
GLG ++ ++ + + + L + V+DADA+ L +K ++ +TPH GE AR
Sbjct 317 GLGNNEHVREFVNEFLKTLEKP----AVIDADAINVLDTSVLKERKSPAVLTPHPGEMAR 372
Query 374 LLDISVAQIEQDRFTAIRQLQQRYNGAWVLKGAGSLSLFHDKIMICTAGNAGMGTGGMGD 433
L+ +V ++ + + + + + VLK A ++ +K + GN G+ GG GD
Sbjct 373 LVKKTVGDVKYN-YELAEEFAKENDCVLVLKSATTIVTDGEKTLFNITGNTGLSKGGSGD 431
Query 434 VLAGMIASLKAQFDDQICLSDV-VTLHAQAGDLLAQNGQRGIQAYDMAKAI 483
VL GMIA AQ + S V V LH A +L Q+ +RG+ A ++ + I
Sbjct 432 VLTGMIAGFIAQGLSPLEASTVSVYLHGFAAELFEQD-ERGLTASELLRLI 481
>P96051 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [Streptococcus
thermophilus]
Length=278
Score = 105 bits (262), Expect = 1e-28
Identities = 78/243 (32%), Positives = 120/243 (49%), Gaps = 12/243 (5%)
Query 233 HKGTYGHVLVVGGHKNMGGAVIMAAEAAFHAGAGKVTVICDALHHSAILARAPNIMIKDI 292
HKG+YG VL+VGG GGA+IMAA A ++GAG VTV D + A+ A P M D+
Sbjct 20 HKGSYGRVLLVGGLYPYGGAIIMAAIACVNSGAGLVTVATDRENIIALHAHLPEAMAFDL 79
Query 293 NQIDAQEIEQILKEIDAVCFGMGLGRDQWAKQTFDVWFQQLHQQQKLHVVLDADALWFLS 352
+ + L+ D + G GLG ++ A ++ + Q L V+D AL L+
Sbjct 80 R--ETERFLDKLRAADVILIGSGLGEEETADWALELVLANIRSNQNL--VVDGSALNLLA 135
Query 353 --DQSIKLGQNFYMTPHAGEAARLLDISVAQIEQDRFTAIRQLQQRYNGAWVLKGAGSLS 410
+QS + +TPH E RL ++++ EQ R L++ +G ++ + +
Sbjct 136 KKNQSSLPKCHLILTPHQKEWERLSGLAIS--EQSVSNTQRALEEFQSGTILVAKSHKTA 193
Query 411 LFHD-KIMICTAGNAGMGTGGMGDVLAGMIASLKAQFDDQICLSDVVT---LHAQAGDLL 466
++ ++ G TGGMGD LAGM+A AQF V+ LH+ D +
Sbjct 194 VYQGAEVTHLEVGGPYQATGGMGDTLAGMVAGFLAQFASTDSYKAVIVATWLHSAIADNI 253
Query 467 AQN 469
A+N
Sbjct 254 AEN 256
>F4FTW6 NAD(P)H-hydrate epimerase [Lentilactobacillus buchneri
(strain NRRL B-30929)]
Length=215
Score = 88.6 bits (218), Expect = 2e-23
Identities = 60/187 (32%), Positives = 95/187 (51%), Gaps = 23/187 (12%)
Query 25 SLGLMQQAAWAISQKLHHHILKNS-LSIKKIAVWCGSGKNAGDGYYIAIYLKSLGYNISI 83
SL LM++A K++ ++L N L + + + G+G N GDG +A L + GY +SI
Sbjct 25 SLVLMERAGL----KIYENMLDNKDLDLSNVLILAGTGNNGGDGLVVARLLATHGYQVSI 80
Query 84 FTM--PAGQSTDLKQAVADAHANQLPISNHFDVN--------NDYDCHIDALFGIGLNRE 133
T+ P S D H Q I N++ + N + +DALFG GL+R
Sbjct 81 LTVGNPDHASED--------HLAQARICNYYQIPKVFMNADFNKFTTLVDALFGSGLSRN 132
Query 134 LDQNWQSIVHHFNRLSGFKVAVDLPSGLNANTGASLPVAIKVDVTYTILAEKIGLFTGQA 193
+ ++ +I+ N + A+D+PSGLN +TG + AIK T T+ K+G+ QA
Sbjct 133 VGGDFATIIDKANASTAKIHAIDIPSGLNGDTGDVMGTAIKAISTSTVAYPKVGMLKDQA 192
Query 194 TEYVGQL 200
Y G++
Sbjct 193 KPYTGKI 199
>D5TAM8 NAD(P)H-hydrate epimerase [Legionella pneumophila serogroup
1 (strain 2300/99 Alcoy)]
Length=270
Score = 73.6 bits (179), Expect = 9e-18
Identities = 57/224 (25%), Positives = 102/224 (46%), Gaps = 15/224 (7%)
Query 1 MQLPVYHSTQIQAWEQRWFEQQN-SSLGLMQQAAWAISQKLHHHILKNSLSIKKIAVWCG 59
M+ P+Y TQ Q Q S L LMQ++ A L + K +KKI+++CG
Sbjct 15 MKTPIYLVTQFQQLMDLMQNQYEVSCLELMQRSGKAACDFLVYRWPK----VKKISIFCG 70
Query 60 SGKNAGDGYYIAIYLKSLGYNISIFTM--------PAGQSTDLKQAVADAHANQLPISNH 111
G N G GY +A K +G +++ + P ++ + H + + +
Sbjct 71 RGDNGGQGYVLAQQAKKMGMVPTVWQVGHQMSMSKPPQMHKEVWYEMNSCHQQGIVLHTY 130
Query 112 F-DVN-NDYDCHIDALFGIGLNRELDQNWQSIVHHFNRLSGFKVAVDLPSGLNANTGASL 169
D++ D + +DALFG+GL + ++ + + +A+++P+G+NA+TG
Sbjct 131 SPDIDLGDPELIVDALFGVGLYGHVRPEIALLLQRLQQFTVPILAIEVPTGINASTGEIA 190
Query 170 PVAIKVDVTYTILAEKIGLFTGQATEYVGQLELISLIPKDNMLQ 213
A+ T T L K+GL Y G++ L+ + + Q
Sbjct 191 GNALAATATITFLCMKLGLLINDGKIYSGEIAFDDLLAPEAIYQ 234
>P94368 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [Bacillus
subtilis (strain 168)]
Length=276
Score = 72.0 bits (175), Expect = 3e-17
Identities = 65/243 (27%), Positives = 103/243 (42%), Gaps = 10/243 (4%)
Query 225 LPIRQSFGHKGTYGHVLVVGGHKNMGGAVIMAAEAAFHAGAGKVTVICDALHHSAILARA 284
LP R + HKGTYG L++ G +M GA ++A A +G GK+ + I+
Sbjct 15 LPERDAESHKGTYGTALLLAGSDDMPGAALLAGLGAMRSGLGKLVIGTSENVIPLIVPVL 74
Query 285 PNIMIKDINQIDAQEIEQILKEIDAVCFGMGLGRDQWAKQTFDVWFQQLHQQQKLHVVLD 344
P A + Q+ + A+ G GL + + +Q D V+LD
Sbjct 75 PEATYWRDGWKKAAD-AQLEETYRAIAIGPGLPQTESVQQAVDHVL-----TADCPVILD 128
Query 345 ADALWFLSDQSIKLGQNFYMTPHAGEAARLLDISVAQIEQDRFTAIRQLQQRYNGAWVLK 404
A AL K +TPH GE R+ + V ++++ R ++ + VLK
Sbjct 129 AGAL--AKRTYPKREGPVILTPHPGEFFRMTGVPVNELQKKRAEYAKEWAAQLQTVIVLK 186
Query 405 GAGSLSLFHD-KIMICTAGNAGMGTGGMGDVLAGMIASLKAQFDD-QICLSDVVTLHAQA 462
G ++ F D + GN + GG GD L GMI + +D + + + V LH
Sbjct 187 GNQTVIAFPDGDCWLNPTGNGALAKGGTGDTLTGMILGMLCCHEDPKHAVLNAVYLHGAC 246
Query 463 GDL 465
+L
Sbjct 247 AEL 249
>B3L9G8 NAD(P)H-hydrate epimerase [Plasmodium knowlesi (strain
H)]
Length=289
Score = 67.0 bits (162), Expect = 2e-15
Identities = 42/150 (28%), Positives = 74/150 (49%), Gaps = 3/150 (2%)
Query 52 KKIAVWCGSGKNAGDGYYIAIYLKSLGYNISIFTMPAGQSTDLKQAVADAHANQLPI--S 109
KKI ++CG G N GDG A +LK GY+I++ ++ + H +P+ S
Sbjct 112 KKILIFCGPGNNGGDGLVAARHLKQFGYDITVAYPKENTKVLFQRLLNLLHHYHVPVVKS 171
Query 110 NHFDVNNDYDCHIDALFGIGLNRELDQNWQSIVHHFNRLSGFKVAVDLPSGLNAN-TGAS 168
+ YD +DALFG E + I+H N+ + V+VD+PSG+N + A
Sbjct 172 ATGEDIKMYDLVVDALFGFSFRGEPRSPFDEIIHMINQSNKPVVSVDVPSGINIDGDTAG 231
Query 169 LPVAIKVDVTYTILAEKIGLFTGQATEYVG 198
+++ ++ +++ K G+ + Y+G
Sbjct 232 TALSVNSEMNISLMLPKEGVRHYRKKHYLG 261
>F8HWV7 NAD(P)H-hydrate epimerase [Leuconostoc sp. (strain C2)]
Length=225
Score = 65.1 bits (157), Expect = 4e-15
Identities = 53/167 (32%), Positives = 79/167 (47%), Gaps = 18/167 (11%)
Query 50 SIKKIAVWCGSGKNAGDGYYIAIYLKSLGYNISIFTMPAGQSTDLKQAVADAHANQLPIS 109
++ I V G G N DG I+ L + G+N+S+ + G T K +V +QL I
Sbjct 45 NLDHILVLAGLGNNGADGVAISRLLYAQGFNVSLQFV--GNVTRAKDSVK----HQLDII 98
Query 110 NHFDVN-------NDYDCHIDALFGIGLNRELDQNWQSIVHHFNRLSGFKVAVDLPSGLN 162
+ + N+ IDA+FG GLN L + Q ++ N + +AVD P+G++
Sbjct 99 EKYGLVHAEKSDFNEATLIIDAIFGTGLNNLLPEGLQKMIKAANHIEKTVIAVDTPTGID 158
Query 163 ANTGASLPVAIKVDVTYTILAEKIGLFTGQATEYVGQLELISLIPKD 209
A TG A+K T T KIGL T+ VG ++I KD
Sbjct 159 ATTGEVRGAALKAHTTVTFGYNKIGL-----TQRVGGYLSGNVIVKD 200
>F4LHM0 NAD(P)H-hydrate epimerase [Bordetella pertussis (strain
CS)]
Length=228
Score = 59.7 bits (143), Expect = 3e-13
Identities = 54/171 (32%), Positives = 78/171 (46%), Gaps = 25/171 (15%)
Query 53 KIAVWCGSGKNAGDGYYIAIYLKSLGYNISIFTMPAGQST---DLKQAVAD--AHANQLP 107
++ G G N GD A L++ GY +++ MPAG + D ++A D A Q
Sbjct 44 QVLALAGPGNNGGDALVAATLLQARGYRVAV-VMPAGPARLPDDARRAWQDWCAAGGQ-- 100
Query 108 ISNHFDVNNDYDCH-----IDALFGIGLNRELDQNWQSIVHHFNRLSGFKVAVDLPSGLN 162
+ D H ID LFGIGL R LD WQ ++ N +A+D+PSGL+
Sbjct 101 ------ASADLPAHAPALVIDGLFGIGLARPLDGAWQGLIDQVNAWRVPVLALDVPSGLS 154
Query 163 ANTGASL--PVAIKVDVTYTI--LAEKIGLFTGQATEYVGQ--LELISLIP 207
A +G L P V T+T+ + L A + G+ L L+ L P
Sbjct 155 AASGQPLGDPPGRPVRATWTLSFIGVPAALRAPGAAAWCGEQYLSLLGLTP 205
>Q6QRN6 NAD(P)H-hydrate epimerase [Bos taurus]
Length=288
Score = 58.2 bits (139), Expect = 2e-12
Identities = 54/222 (24%), Positives = 93/222 (42%), Gaps = 9/222 (4%)
Query 10 QIQAWEQRWFEQQNSSLG-LMQQAAWAISQKLHHHILKNSLSIKK--IAVWCGSGKNAGD 66
+ QA +Q F + S+ LM+ A + + + SLS + V CG G N GD
Sbjct 64 EAQAVDQELFNEYQFSVDQLMELAGLSCATAIAKAYPPTSLSRSPPTVLVICGPGNNGGD 123
Query 67 GYYIAIYLKSLGYNISIFTMPAGQSTDLKQAVADAHANQLPISNHFD-----VNNDYDCH 121
G A +LK GY +I+ V +P ++ Y+
Sbjct 124 GLVCARHLKLFGYQPTIYYPKRPNKPLFTALVTQCQKMDIPFLGEMPPEPMLIDELYELV 183
Query 122 IDALFGIGLNRELDQNWQSIVHHFNRLSGFKVAVDLPSGLNANTGASLPVAIKVDVTYTI 181
+DA+FG E+ + ++SI+ N L+ ++D+PSG + G+S + + ++ T
Sbjct 184 VDAIFGFSFTGEVREPFRSILSVLNGLTVPIASIDIPSGWDVEKGSSGGIQPDLLISLTA 243
Query 182 LAEKIGLFTGQATEYVGQLELISLIPKDNMLQAFAYLSTQQV 223
+ FTG+ Y+G + + K L Y T+ V
Sbjct 244 PKKSATQFTGR-YHYLGGRFVPPALEKKYQLNLPPYPDTECV 284
Lambda K H a alpha
0.323 0.136 0.412 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 2793796
Database: 0467271e3a8efed2b525bf3beada3bda.SwissProt.fasta
Posted date: Jun 1, 2024 8:23 AM
Number of letters in database: 7,300
Number of sequences in database: 18
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
