BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 97cac0d3b55e49f76bea111fd5405f91.SwissProt.fasta
16 sequences; 5,640 total letters
Query= ACIAD2088
Length=356
Score E
Sequences producing significant alignments: (Bits) Value
P10172 Glutaminase-asparaginase [Acinetobacter glutaminasificans] 585 0.0
Q9I407 Glutaminase-asparaginase [Pseudomonas aeruginosa (strain A... 407 1e-145
O68897 Glutaminase-asparaginase [Pseudomonas fluorescens biotype A] 407 2e-145
Q88K39 Glutaminase-asparaginase [Pseudomonas putida (strain ATCC ... 401 2e-143
P10182 Glutaminase-asparaginase [Pseudomonas sp. (strain ATCC 295... 393 2e-140
P50286 L-asparaginase [Wolinella succinogenes (strain ATCC 29543 ... 278 3e-95
O34482 L-asparaginase 2 [Bacillus subtilis (strain 168)] 277 2e-94
P00805 L-asparaginase 2 [Escherichia coli (strain K12)] 275 6e-94
P43843 Probable L-asparaginase periplasmic [Haemophilus influenza... 275 6e-94
Q9ZLB9 Probable L-asparaginase [Helicobacter pylori (strain J99 /... 259 8e-88
P06608 L-asparaginase [Dickeya chrysanthemi] 251 2e-84
Q9UTS7 Probable L-asparaginase 2 [Schizosaccharomyces pombe (stra... 215 2e-70
P0CX79 L-asparaginase 2-4 [Saccharomyces cerevisiae (strain ATCC ... 178 4e-56
P0CX78 L-asparaginase 2-3 [Saccharomyces cerevisiae (strain ATCC ... 178 4e-56
P0CX77 L-asparaginase 2-2 [Saccharomyces cerevisiae (strain ATCC ... 178 4e-56
P0CZ17 L-asparaginase 2-1 [Saccharomyces cerevisiae (strain ATCC ... 178 4e-56
>P10172 Glutaminase-asparaginase [Acinetobacter glutaminasificans]
Length=331
Score = 585 bits (1508), Expect = 0.0
Identities = 290/331 (88%), Positives = 315/331 (95%), Gaps = 0/331 (0%)
Query 25 KNNVVVVATGGTIAGAGASSTNSATYTAAKVPVDALINAVPQIKDLANVSGIQALQIASE 84
KNNVV+VATGGTIAGAGASSTNSATY+AAKVPVDALI AVPQ+ DLAN++GIQALQ+ASE
Sbjct 1 KNNVVIVATGGTIAGAGASSTNSATYSAAKVPVDALIKAVPQVNDLANITGIQALQVASE 60
Query 85 SITDKELLSLARQVNDLVKKPSVNGVVITHGTDTLEETAFFLNLVIHTDKPIVLVGSMRP 144
SITDKELLSLARQVNDLVKKPSVNGVVITHGTDT+EETAFFLNLV+HTDKPIVLVGSMRP
Sbjct 61 SITDKELLSLARQVNDLVKKPSVNGVVITHGTDTMEETAFFLNLVVHTDKPIVLVGSMRP 120
Query 145 STALSADGPLNLYSAVALAASDEAKNKGVMVLMNDSIFAARDVTKGINIHTNAFVSQWGE 204
STALSADGPLNLYSAVALA+S+EAKNKGVMVLMNDSIFAARDVTKGINIHT+AFVSQWG
Sbjct 121 STALSADGPLNLYSAVALASSNEAKNKGVMVLMNDSIFAARDVTKGINIHTHAFVSQWGA 180
Query 205 LGTLVEGKPYWFRSSVKRHTNASEFNIENIKGDQLPLVQIVYGSDSMIPDAYLAYAKAGA 264
LGTLVEGKPYWFRSSVK+HTN SEFNIE I+GD LP VQIVYGSD+M+PDAY A+AKAG
Sbjct 181 LGTLVEGKPYWFRSSVKKHTNNSEFNIEKIQGDALPGVQIVYGSDNMMPDAYQAFAKAGV 240
Query 265 KAIINAGTGNGSVGNYIVPTLKKLHDEQGIQIIRSSRVPQGFVLRNAEQPDDQYGWVVAH 324
KAII+AGTGNGS+ NY+VP ++KLHDEQG+QI+RSSRV QGFVLRNAEQPDD+YGW+ AH
Sbjct 241 KAIIHAGTGNGSMANYLVPEVRKLHDEQGLQIVRSSRVAQGFVLRNAEQPDDKYGWIAAH 300
Query 325 DLNPQKARLLAALALTKTNDAKEIQRMFWQY 355
DLNPQKARLL ALALTKTNDAKEIQ MFW Y
Sbjct 301 DLNPQKARLLMALALTKTNDAKEIQNMFWNY 331
>Q9I407 Glutaminase-asparaginase [Pseudomonas aeruginosa (strain
ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228
/ 1C / PRS 101 / PAO1)]
Length=362
Score = 407 bits (1046), Expect = 1e-145
Identities = 211/331 (64%), Positives = 259/331 (78%), Gaps = 4/331 (1%)
Query 26 NNVVVVATGGTIAGAGASSTNSATYTAAKVPVDALINAVPQIKDLANVSGIQALQIASES 85
+NVV++ATGGTIAGAGAS+ NSATYTAAKVPVD L+ +VPQ+KD+ANV G Q QIASES
Sbjct 35 SNVVILATGGTIAGAGASAANSATYTAAKVPVDQLLASVPQLKDIANVRGEQVFQIASES 94
Query 86 ITDKELLSLARQVNDLVKKPSVNGVVITHGTDTLEETAFFLNLVIHTDKPIVLVGSMRPS 145
T++ LL L + V L V+G+VITHGTDTLEETA+FL LV HT+KPIV+VGSMRP
Sbjct 95 FTNENLLELGKTVAKLADSDDVDGIVITHGTDTLEETAYFLTLVEHTEKPIVVVGSMRPG 154
Query 146 TALSADGPLNLYSAVALAASDEAKNKGVMVLMNDSIFAARDVTKGINIHTNAFVSQWGEL 205
TA+SADG LNLY+AVA+A A+ KGV++ MND I + RD +K +NI T AF S WG L
Sbjct 155 TAMSADGMLNLYNAVAVAGDKSARGKGVLITMNDEILSGRDASKMVNIKTEAFKSPWGPL 214
Query 206 GTLVEGKPYWFRSSVKRHTNASEFNIENIKGDQLPLVQIVYGSDSMIPDAYLAYAKAGAK 265
G +VEGK YWFR+ VKRHT SEF+I+ I L V+I Y ++ AY A A+AGAK
Sbjct 215 GMVVEGKSYWFRAPVKRHTVNSEFDIKQISA--LAPVEIAYSYGNVSDTAYKALAQAGAK 272
Query 266 AIINAGTGNGSVGNYIVPTLKKLHDEQGIQIIRSSRV-PQGFVLRNAEQPDDQYGWVVAH 324
AII+AGTGNGSV +VPTL++L +QG+QIIRSS V GFVLRNAEQPDD+ W+VAH
Sbjct 273 AIIHAGTGNGSVPARVVPTLQELR-KQGVQIIRSSHVNAGGFVLRNAEQPDDKNDWIVAH 331
Query 325 DLNPQKARLLAALALTKTNDAKEIQRMFWQY 355
DLNPQKAR+LAA+A+TKT D+KE+QR+FW+Y
Sbjct 332 DLNPQKARILAAVAMTKTQDSKELQRIFWEY 362
>O68897 Glutaminase-asparaginase [Pseudomonas fluorescens biotype
A]
Length=362
Score = 407 bits (1045), Expect = 2e-145
Identities = 213/330 (65%), Positives = 259/330 (78%), Gaps = 4/330 (1%)
Query 27 NVVVVATGGTIAGAGASSTNSATYTAAKVPVDALINAVPQIKDLANVSGIQALQIASESI 86
NVV++ATGGTIAGAGAS+ NSATY AAKV ++ LI VP++ +ANV G Q +QIASESI
Sbjct 36 NVVILATGGTIAGAGASAANSATYQAAKVGIEQLIAGVPELSQIANVRGEQVMQIASESI 95
Query 87 TDKELLSLARQVNDLVKKPSVNGVVITHGTDTLEETAFFLNLVIHTDKPIVLVGSMRPST 146
++ LL L R+V +L V+G+VITHGTDTLEETA+FLNLV TDKPI++VGSMRP T
Sbjct 96 NNENLLQLGRRVAELADSKDVDGIVITHGTDTLEETAYFLNLVEKTDKPIIVVGSMRPGT 155
Query 147 ALSADGPLNLYSAVALAASDEAKNKGVMVLMNDSIFAARDVTKGINIHTNAFVSQWGELG 206
A+SADG LNLY+AVA+A S +A+ KGV+V MND I + RDV+K INI T AF S WG LG
Sbjct 156 AMSADGMLNLYNAVAVAGSKDARGKGVLVTMNDEIQSGRDVSKMINIKTEAFKSPWGPLG 215
Query 207 TLVEGKPYWFRSSVKRHTNASEFNIENIKGDQLPLVQIVYGSDSMIPDAYLAYAKAGAKA 266
+VEGK YWFR KRHT SEF+I+ IK LP V+I YG ++ A A A+AGAKA
Sbjct 216 MVVEGKSYWFRLPAKRHTMDSEFDIKTIK--SLPDVEIAYGYGNVSDTAVKALAQAGAKA 273
Query 267 IINAGTGNGSVGNYIVPTLKKLHDEQGIQIIRSSRV-PQGFVLRNAEQPDDQYGWVVAHD 325
II+AGTGNGSV + +VP L++L +QG+QIIRSS V GFVLRNAEQPDD+Y WVVAHD
Sbjct 274 IIHAGTGNGSVSSKVVPALQELR-KQGVQIIRSSHVNAGGFVLRNAEQPDDKYDWVVAHD 332
Query 326 LNPQKARLLAALALTKTNDAKEIQRMFWQY 355
LNPQKAR+LA +ALTKT D+KE+QRMFW+Y
Sbjct 333 LNPQKARILAMVALTKTQDSKELQRMFWEY 362
>Q88K39 Glutaminase-asparaginase [Pseudomonas putida (strain ATCC
47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)]
Length=362
Score = 401 bits (1031), Expect = 2e-143
Identities = 207/330 (63%), Positives = 259/330 (78%), Gaps = 4/330 (1%)
Query 27 NVVVVATGGTIAGAGASSTNSATYTAAKVPVDALINAVPQIKDLANVSGIQALQIASESI 86
NVV++ATGGTIAGAGAS+ NSATY AAK+ VD LI VP++ D+ANV G Q +QIASESI
Sbjct 36 NVVILATGGTIAGAGASAANSATYQAAKLGVDKLIAGVPELADIANVRGEQVMQIASESI 95
Query 87 TDKELLSLARQVNDLVKKPSVNGVVITHGTDTLEETAFFLNLVIHTDKPIVLVGSMRPST 146
++ +LL L ++V +L + V+G+VITHGTDTLEETAFFLNLV TDKPIV+VGSMRP T
Sbjct 96 SNDDLLKLGKRVAELAESKDVDGIVITHGTDTLEETAFFLNLVEKTDKPIVVVGSMRPGT 155
Query 147 ALSADGPLNLYSAVALAASDEAKNKGVMVLMNDSIFAARDVTKGINIHTNAFVSQWGELG 206
A+SADG LNLY+AVA+A+ +++ KGV+V MND I + RDV+K +NI T AF S WG +G
Sbjct 156 AMSADGMLNLYNAVAVASDKQSRGKGVLVTMNDEIQSGRDVSKAVNIKTEAFKSAWGPMG 215
Query 207 TLVEGKPYWFRSSVKRHTNASEFNIENIKGDQLPLVQIVYGSDSMIPDAYLAYAKAGAKA 266
+VEGK YWFR KRHT SEF+I+ I LP V I YG ++ AY A A+ GAKA
Sbjct 216 MVVEGKSYWFRLPAKRHTVNSEFDIKQI--SSLPQVDIAYGYGNVTDTAYKALAQNGAKA 273
Query 267 IINAGTGNGSVGNYIVPTLKKLHDEQGIQIIRSSRVPQ-GFVLRNAEQPDDQYGWVVAHD 325
+I+AGTGNGSV + +VP L++L + G+QIIRSS V Q GFVLRNAEQPDD+ WVVAHD
Sbjct 274 LIHAGTGNGSVSSRVVPALQELR-KNGVQIIRSSHVNQGGFVLRNAEQPDDKNDWVVAHD 332
Query 326 LNPQKARLLAALALTKTNDAKEIQRMFWQY 355
LNPQKAR+LA +A+TKT D+KE+QR+FW+Y
Sbjct 333 LNPQKARILAMVAMTKTQDSKELQRIFWEY 362
>P10182 Glutaminase-asparaginase [Pseudomonas sp. (strain ATCC
29598 / 7A)]
Length=337
Score = 393 bits (1009), Expect = 2e-140
Identities = 205/330 (62%), Positives = 254/330 (77%), Gaps = 4/330 (1%)
Query 27 NVVVVATGGTIAGAGASSTNSATYTAAKVPVDALINAVPQIKDLANVSGIQALQIASESI 86
NVV++ATGGTIAGAGAS+ NSATY AAKV VD LI VP++ DLANV G Q +QIASESI
Sbjct 11 NVVILATGGTIAGAGASAANSATYQAAKVGVDKLIAGVPELADLANVRGEQVMQIASESI 70
Query 87 TDKELLSLARQVNDLVKKPSVNGVVITHGTDTLEETAFFLNLVIHTDKPIVLVGSMRPST 146
T+ +LL L ++V +L V+G+VITHGTDTLEETA+FL+L ++TDKPIV+VGSMRP T
Sbjct 71 TNDDLLKLGKRVAELADSNDVDGIVITHGTDTLEETAYFLDLTLNTDKPIVVVGSMRPGT 130
Query 147 ALSADGPLNLYSAVALAASDEAKNKGVMVLMNDSIFAARDVTKGINIHTNAFVSQWGELG 206
A+SADG LNLY+AVA+A++ +++ KGV+V MND I + RDV+K INI T AF S WG LG
Sbjct 131 AMSADGMLNLYNAVAVASNKDSRGKGVLVTMNDEIQSGRDVSKSINIKTEAFKSAWGPLG 190
Query 207 TLVEGKPYWFRSSVKRHTNASEFNIENIKGDQLPLVQIVYGSDSMIPDAYLAYAKAGAKA 266
+VEGK YWFR KRHT SEF+I+ I LP V I Y ++ AY A A+ GAKA
Sbjct 191 MVVEGKSYWFRLPAKRHTVNSEFDIKQI--SSLPQVDIAYSYGNVTDTAYKALAQNGAKA 248
Query 267 IINAGTGNGSVGNYIVPTLKKLHDEQGIQIIRSSRVPQ-GFVLRNAEQPDDQYGWVVAHD 325
+I+AGTGNGSV + + P L+ L + G QIIRSS V Q GFVLRNAEQPDD+ WVVAHD
Sbjct 249 LIHAGTGNGSVSSRLTPALQTLR-KTGTQIIRSSHVNQGGFVLRNAEQPDDKNDWVVAHD 307
Query 326 LNPQKARLLAALALTKTNDAKEIQRMFWQY 355
LNP+KAR+L LA+ KT D+KE+QR+FW+Y
Sbjct 308 LNPEKARILVELAMVKTQDSKELQRIFWEY 337
>P50286 L-asparaginase [Wolinella succinogenes (strain ATCC 29543
/ DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W)]
Length=330
Score = 278 bits (710), Expect = 3e-95
Identities = 159/333 (48%), Positives = 215/333 (65%), Gaps = 5/333 (2%)
Query 24 AKNNVVVVATGGTIAGAGASSTNSATYTAAKVPVDALINAVPQIKDLANVSGIQALQIAS 83
AK V ++ATGGTIAG+G SS S+ Y+A V VD L+ AVP I DLA + G Q I S
Sbjct 2 AKPQVTILATGGTIAGSGESSVKSS-YSAGAVTVDKLLAAVPAINDLATIKGEQISSIGS 60
Query 84 ESITDKELLSLARQVNDLVKKPSVNGVVITHGTDTLEETAFFLNLVIHTDKPIVLVGSMR 143
+ +T K L LA++VN+L+ + V+ITHGTDT+EETAFFLNL + + KP+VLVG+MR
Sbjct 61 QEMTGKVWLKLAKRVNELLAQKETEAVIITHGTDTMEETAFFLNLTVKSQKPVVLVGAMR 120
Query 144 PSTALSADGPLNLYSAVALAASDEAKNKGVMVLMNDSIFAARDVTKGINIHTNAFVS-QW 202
+++SADGP+NLY+AV +A + + NKGV+++MND I AAR+ TK NAF S
Sbjct 121 SGSSMSADGPMNLYNAVNVAINKASTNKGVVIVMNDEIHAAREATKLNTTAVNAFASPNT 180
Query 203 GELGTLVEGKPYWFRSSVKRHTNASEFNIENIKGDQLPLVQIVYGSDSMIPDAYLAYAKA 262
G++GT+ GK +F SV+ HT ASEF+I I ++LP V I+Y A +A
Sbjct 181 GKIGTVYYGKVEYFTQSVRPHTLASEFDISKI--EELPRVDILYAHPDDTDVLVNAALQA 238
Query 263 GAKAIINAGTGNGSVGNYIVPTLKKLHDEQGIQIIRSSRVPQGFVLRNAEQPDDQYGWVV 322
GAK II+AG GNG+ L+K + G+ + RSSRV G + AE D + G+V
Sbjct 239 GAKGIIHAGMGNGNPFPLTQNALEKA-AKSGVVVARSSRVGSGSTTQEAEVDDKKLGFVA 297
Query 323 AHDLNPQKARLLAALALTKTNDAKEIQRMFWQY 355
LNPQKAR+L LALTKT+D + IQ++F Y
Sbjct 298 TESLNPQKARVLLMLALTKTSDREAIQKIFSTY 330
>O34482 L-asparaginase 2 [Bacillus subtilis (strain 168)]
Length=375
Score = 277 bits (708), Expect = 2e-94
Identities = 154/333 (46%), Positives = 225/333 (68%), Gaps = 13/333 (4%)
Query 27 NVVVVATGGTIAGAGASSTNSATYTAAKVPVDALINAVPQIKDLANVSGIQALQIASESI 86
N+ ++ATGGTIAGA S T++ Y A V V++LI AVP++KD+ANVSG Q + + S +I
Sbjct 52 NIRILATGGTIAGADQSKTSTTEYKAGVVGVESLIEAVPEMKDIANVSGEQIVNVGSTNI 111
Query 87 TDKELLSLARQVNDLVKKPSVNGVVITHGTDTLEETAFFLNLVIHTDKPIVLVGSMRPST 146
+K LL LA+++N L+ V+G+V+THGTDTLEETA+FLNL + +DKP+V+VGSMRPST
Sbjct 112 DNKILLKLAKRINHLLASDDVDGIVVTHGTDTLEETAYFLNLTVKSDKPVVIVGSMRPST 171
Query 147 ALSADGPLNLYSAVALAASDEAKNKGVMVLMNDSIFAARDVTKGINIHTNAFVS-QWGEL 205
A+SADGP NLY+AV +A + EAK KG +V++ND I +AR VTK T+ F S + G +
Sbjct 172 AISADGPSNLYNAVKVAGAPEAKGKGTLVVLNDRIASARYVTKTNTTTTDTFKSEEMGFV 231
Query 206 GTLVEGKPYWFRSSVKRHTNASEFNIENIKGDQLPLVQIVYGSDSMIPDAYLAYAKAGAK 265
GT+ + Y+ ++HT ++F++ N+ D+LP V I+YG + + A KAGAK
Sbjct 232 GTIAD-DIYFNNEITRKHTKDTDFSVSNL--DELPQVDIIYGYQNDGSYLFDAAVKAGAK 288
Query 266 AIINAGTGNGSVGNYIVPTLKKLHD---EQGIQIIRSSRVPQGFVLRNAEQPDDQYGWVV 322
I+ AG+GNGS+ + +K D ++G+ ++RS+R G V N + + +
Sbjct 289 GIVFAGSGNGSLSD----AAEKGADSAVKKGVTVVRSTRTGNGVVTPNQDYAEKDL--LA 342
Query 323 AHDLNPQKARLLAALALTKTNDAKEIQRMFWQY 355
++ LNPQKAR+L LALTKTND ++IQ F +Y
Sbjct 343 SNSLNPQKARMLLMLALTKTNDPQKIQAYFNEY 375
>P00805 L-asparaginase 2 [Escherichia coli (strain K12)]
Length=348
Score = 275 bits (703), Expect = 6e-94
Identities = 155/350 (44%), Positives = 223/350 (64%), Gaps = 7/350 (2%)
Query 7 KSFGLGLTLLAASVSLYAKNNVVVVATGGTIAGAGASSTNSATYTAAKVPVDALINAVPQ 66
K L ++ S + A N+ ++ATGGTIAG G S+T S YT KV V+ L+NAVPQ
Sbjct 5 KKTALAALVMGFSGAALALPNITILATGGTIAGGGDSATKS-NYTVGKVGVENLVNAVPQ 63
Query 67 IKDLANVSGIQALQIASESITDKELLSLARQVNDLVKKPSVNGVVITHGTDTLEETAFFL 126
+KD+ANV G Q + I S+ + D L+LA+++N K +G VITHGTDT+EETA+FL
Sbjct 64 LKDIANVKGEQVVNIGSQDMNDNVWLTLAKKINTDCDK--TDGFVITHGTDTMEETAYFL 121
Query 127 NLVIHTDKPIVLVGSMRPSTALSADGPLNLYSAVALAASDEAKNKGVMVLMNDSIFAARD 186
+L + DKP+V+VG+MRPST++SADGP NLY+AV AA + N+GV+V+MND++ RD
Sbjct 122 DLTVKCDKPVVMVGAMRPSTSMSADGPFNLYNAVVTAADKASANRGVLVVMNDTVLDGRD 181
Query 187 VTKGINIHTNAFVS-QWGELGTLVEGKPYWFRSSVKRHTNASEFNIENIKGDQLPLVQIV 245
VTK F S +G LG + GK + R+ ++HT+ + F++ + ++LP V IV
Sbjct 182 VTKTNTTDVATFKSVNYGPLGYIHNGKIDYQRTPARKHTSDTPFDVSKL--NELPKVGIV 239
Query 246 YGSDSMIPDAYLAYAKAGAKAIINAGTGNGSVGNYIVPTLKKLHDEQGIQIIRSSRVPQG 305
Y + A AG I++AG GNG++ + TL + G ++RSSRVP G
Sbjct 240 YNYANASDLPAKALVDAGYDGIVSAGVGNGNLYKSVFDTLATA-AKTGTAVVRSSRVPTG 298
Query 306 FVLRNAEQPDDQYGWVVAHDLNPQKARLLAALALTKTNDAKEIQRMFWQY 355
++AE D +YG+V + LNPQKAR+L LALT+T D ++IQ++F QY
Sbjct 299 ATTQDAEVDDAKYGFVASGTLNPQKARVLLQLALTQTKDPQQIQQIFNQY 348
>P43843 Probable L-asparaginase periplasmic [Haemophilus influenzae
(strain ATCC 51907 / DSM 11121 / KW20 / Rd)]
Length=349
Score = 275 bits (703), Expect = 6e-94
Identities = 155/345 (45%), Positives = 223/345 (65%), Gaps = 11/345 (3%)
Query 9 FGLGLTLLAASVSLYAKNNVVVVATGGTIAGAGASSTNSATYTAAKVPVDALINAVPQIK 68
FGLG+++ A+ N+ ++ATGGTIAG+G SS NSA Y A ++ +D LI AVP++K
Sbjct 12 FGLGVSIANAA----DLPNITILATGGTIAGSGQSSVNSA-YKAGQLSIDTLIEAVPEMK 66
Query 69 DLANVSGIQALQIASESITDKELLSLARQVNDLVKKPSVNGVVITHGTDTLEETAFFLNL 128
++AN+ G Q ++I S+ + D+ L LA+ +N K S +G VITHGTDT+EETA+FL+L
Sbjct 67 NIANIKGEQIVKIGSQDMNDEVWLKLAKAINAQCK--STDGFVITHGTDTMEETAYFLDL 124
Query 129 VIHTDKPIVLVGSMRPSTALSADGPLNLYSAVALAASDEAKNKGVMVLMNDSIFAARDVT 188
+ +KP+VLVG+MRP+T SADGPLNLY+AV +AA ++ +GV+V MN+ + ARDVT
Sbjct 125 TVKCEKPVVLVGAMRPATEKSADGPLNLYNAVVVAADKKSSGRGVLVAMNNEVLGARDVT 184
Query 189 KGINIHTNAFVS-QWGELGTLVEGKPYWFRSSVKRHTNASEFNIENIKGDQLPLVQIVYG 247
K F S +G LG + K + RS +HT + FN+E + D LP V I+Y
Sbjct 185 KTSTTAVQTFHSPNYGSLGYIHNSKVDYERSPESKHTINTPFNVEKL--DSLPKVGIIYA 242
Query 248 SDSMIPDAYLAYAKAGAKAIINAGTGNGSVGNYIVPTLKKLHDEQGIQIIRSSRVPQGFV 307
+ + A AG + I++AG GNG+V + L+K + + ++RSSRVP G+
Sbjct 243 YSNAPVEPLNALLNAGYQGIVSAGVGNGNVNAAHLDRLEKA-AKDSVVVVRSSRVPTGYT 301
Query 308 LRNAEQPDDQYGWVVAHDLNPQKARLLAALALTKTNDAKEIQRMF 352
R+AE D +YG+V + LNPQKAR+L LALT+T D K IQ+ F
Sbjct 302 TRDAEVDDSKYGFVASGTLNPQKARVLLQLALTQTKDPKVIQQYF 346
>Q9ZLB9 Probable L-asparaginase [Helicobacter pylori (strain J99
/ ATCC 700824)]
Length=332
Score = 259 bits (661), Expect = 8e-88
Identities = 137/329 (42%), Positives = 215/329 (65%), Gaps = 5/329 (2%)
Query 28 VVVVATGGTIAGAGASSTNSATYTAAKVPVDALINAVPQIKDLANVSGIQALQIASESIT 87
+ ++ATGGTIAG+G ++ +Y + ++ V L+ A+P + +A + G Q I S+ +
Sbjct 8 IALLATGGTIAGSGVDAS-LGSYKSGELGVKELLKAIPSLNKIARIQGEQVSNIGSQDMN 66
Query 88 DKELLSLARQVNDLVKKPSVNGVVITHGTDTLEETAFFLNLVIHTDKPIVLVGSMRPSTA 147
++ LA++ +L+ + GVVITHGTDTLEE+A+FLNLV+H+ KP+VLVG+MR +++
Sbjct 67 EEIWFKLAQRAQELLDDSRIQGVVITHGTDTLEESAYFLNLVLHSTKPVVLVGAMRNASS 126
Query 148 LSADGPLNLYSAVALAASDEAKNKGVMVLMNDSIFAARDVTKGINIHTNAFVS-QWGELG 206
LSADG LNLY AV++A ++++ NKGV+V+M+D+IF R+V K H + F + G +G
Sbjct 127 LSADGALNLYYAVSVAVNEKSANKGVLVVMDDTIFRVREVVKTHTTHISTFKALNSGAIG 186
Query 207 TLVEGKPYWFRSSVKRHTNASEFNIENIKGDQLPLVQIVYGSDSMIPDAYLAYAKAGAKA 266
++ GK ++ +++HT SEF++ +K LP V I+Y M PD + A + AK
Sbjct 187 SVYYGKTRYYMQPLRKHTTESEFSLSQLK-TPLPKVDIIYTHAGMTPDLFQASLNSHAKG 245
Query 267 IINAGTGNGSVGNYIVPTLKKLHDEQGIQIIRSSRVPQGFVLRNAEQPDDQYGWVVAHDL 326
++ AG GNG+V + +++ + G+ I+RSSRV G V + E D YG++ + +L
Sbjct 246 VVIAGVGNGNVSAGFLKAMQEA-SQMGVVIVRSSRVGSGGV-TSGEIDDKAYGFITSDNL 303
Query 327 NPQKARLLAALALTKTNDAKEIQRMFWQY 355
NPQKAR+L LALTKTND +IQ MF +Y
Sbjct 304 NPQKARVLLQLALTKTNDKAKIQEMFEEY 332
>P06608 L-asparaginase [Dickeya chrysanthemi]
Length=348
Score = 251 bits (640), Expect = 2e-84
Identities = 142/330 (43%), Positives = 209/330 (63%), Gaps = 9/330 (3%)
Query 27 NVVVVATGGTIAGAGASSTNSATYTAAKVPVDALINAVPQIKDLANVSGIQALQIASESI 86
N+V++ATGGTIAG+ A+ T + Y A + VD LINAVP++K LANV G Q +ASE++
Sbjct 27 NIVILATGGTIAGSAATGTQTTGYKAGALGVDTLINAVPEVKKLANVKGEQFSNMASENM 86
Query 87 TDKELLSLARQVNDLVKKPSVNGVVITHGTDTLEETAFFLNLVIHTDKPIVLVGSMRPST 146
T +L L+++VN+L+ + V+GVVITHGTDT+EE+A+FL+L + +DKP+V V +MRP+T
Sbjct 87 TGDVVLKLSQRVNELLARDDVDGVVITHGTDTVEESAYFLHLTVKSDKPVVFVAAMRPAT 146
Query 147 ALSADGPLNLYSAVALAASDEAKNKGVMVLMNDSIFAARDVTKGINIHTNAF-VSQWGEL 205
A+SADGP+NL AV +A +++ +GVMV++ND I +AR +TK + F ++ G L
Sbjct 147 AISADGPMNLLEAVRVAGDKQSRGRGVMVVLNDRIGSARYITKTNASTLDTFKANEEGYL 206
Query 206 GTLVEGKPYWFRSSVKRHTNASEFNIENIKGDQLPLVQIVYGSDSMIPDAYLAYAKAGAK 265
G ++ + Y+ K HT S F++ + LP V I+YG Y A + G K
Sbjct 207 GVIIGNRIYYQNRIDKLHTTRSVFDVRGL--TSLPKVDILYGYQDDPEYLYDAAIQHGVK 264
Query 266 AIINAGTGNGSVGNYIVPTLKKLHDEQGIQIIRSSRVPQGFVLRNAEQPDDQYGWVVAHD 325
I+ AG G GSV + ++K E+G+ +IRS+R G V PD++ +V+
Sbjct 265 GIVYAGMGAGSVSVRGIAGMRKAM-EKGVVVIRSTRTGNGIV-----PPDEELPGLVSDS 318
Query 326 LNPQKARLLAALALTKTNDAKEIQRMFWQY 355
LNP AR+L LALT+T+D K IQ F Y
Sbjct 319 LNPAHARILLMLALTRTSDPKVIQEYFHTY 348
>Q9UTS7 Probable L-asparaginase 2 [Schizosaccharomyces pombe (strain
972 / ATCC 24843)]
Length=356
Score = 215 bits (547), Expect = 2e-70
Identities = 133/330 (40%), Positives = 197/330 (60%), Gaps = 17/330 (5%)
Query 27 NVVVVATGGTIAGAGASSTNSATYTAAKVPVDALINAVPQIKDLANVSGIQALQIASESI 86
NV V A GGTIAG SS Y V ++ LI AVP IK +AN++G+Q + SE++
Sbjct 37 NVTVFAMGGTIAGCANSSLEIVNYIPGSVGIEKLIEAVPAIKAIANINGVQVTNMGSENL 96
Query 87 TDKELLSLARQVNDLVKKPSVNGVVITHGTDTLEETAFFLNLVIHTDKPIVLVGSMRPST 146
T ++L LA+ + V KP+V+G+VITHGTD+LEETA FL+L I T KPIV+VG+MRPST
Sbjct 97 TPADVLKLAKLILAEVAKPNVHGIVITHGTDSLEETAMFLDLTISTAKPIVVVGAMRPST 156
Query 147 ALSADGPLNLYSAVALAASDEAKNKGVMVLMNDSIFAARDVTKGINIHTNAFVS-QWGEL 205
A+ ADGP+NL +AVA+A+S+++ +G +VL+ND I +A TK + F S + G L
Sbjct 157 AIGADGPMNLLNAVAVASSNQSMGRGTLVLLNDRIGSAFYTTKTNGNTLDTFKSYEAGSL 216
Query 206 GTLVEGKPYWFRSSVKRHTNASEFNIENIKGDQLPLVQIVYGSDSMIPDAYLAYAKAGAK 265
G ++ KP++F S T F+I NIK QLP V I+YG + P + GAK
Sbjct 217 GIVLNQKPFYFFSPAV-PTGKVFFDIYNIK--QLPRVDILYGYQGLNPKLAESAVHLGAK 273
Query 266 AIINAGTGNGS---VGNYIVPTLKKLHDEQGIQIIRSSRVPQGFVLRNAEQPDDQYGWVV 322
++ A G S GN ++ +L + H+ I ++ S R +G+ + +
Sbjct 274 GLVLAAMGATSWTDDGNEVISSLIREHN---IPVVYSHRTAEGY-------SSNSCLGIP 323
Query 323 AHDLNPQKARLLAALALTKTNDAKEIQRMF 352
++ LNPQKAR + LA++ ++I+ +F
Sbjct 324 SYFLNPQKARYMLMLAISSGYSIRDIEDLF 353
>P0CX79 L-asparaginase 2-4 [Saccharomyces cerevisiae (strain ATCC
204508 / S288c)]
Length=362
Score = 178 bits (451), Expect = 4e-56
Identities = 115/330 (35%), Positives = 181/330 (55%), Gaps = 11/330 (3%)
Query 27 NVVVVATGGTIAGAGASSTNSATYTAAKVPVDALINAVPQIKDLANVSGIQALQIASESI 86
++ + TGGTIA G++S +A Y+ + V+ LI AVP + + AN+ +Q + S S+
Sbjct 34 SIKIFGTGGTIASKGSTSATTAGYSVG-LTVNDLIEAVPSLAEKANLDYLQVSNVGSNSL 92
Query 87 TDKELLSLARQVNDLVKKPSVNGVVITHGTDTLEETAFFLNLVIHTDKPIVLVGSMRPST 146
L+ L +++ + G V+THGTDT+EETAFFL+L I+++KP+ + G+MRP+T
Sbjct 93 NYTHLIPLYHGISEALASDDYAGAVVTHGTDTMEETAFFLDLTINSEKPVCIAGAMRPAT 152
Query 147 ALSADGPLNLYSAVALAASDEAKNKGVMVLMNDSIFAARDVTK-GINIHTNAFVSQWGEL 205
A SADGP+NLY AV++AAS+++ +G M+ +ND I + TK N + G L
Sbjct 153 ATSADGPMNLYQAVSIAASEKSLGRGTMITLNDRIASGFWTTKMNANSLDTFRADEQGYL 212
Query 206 GTLVEGKPYWFRSSVKRHTNASEFNIENIKG-DQLPLVQIVYGSDSMIPDAYLAYAK-AG 263
G ++ VK + F+I N+ ++P V I+Y + P+ + K G
Sbjct 213 GYFSNDDVEFYYPPVKPN-GWQFFDISNLTDPSEIPEVIILYSYQGLNPELIVKAVKDLG 271
Query 264 AKAIINAGTGNGSVGNYIVPTLKKLHDEQGIQIIRSSRVPQGFVLRNAEQPDDQYGWVVA 323
AK I+ AG+G GS ++L++E GI I+ S R G V PDD + +
Sbjct 272 AKGIVLAGSGAGSWTATGSIVNEQLYEEYGIPIVHSRRTADGTV-----PPDDAPEYAIG 326
Query 324 HD-LNPQKARLLAALALTKTNDAKEIQRMF 352
LNPQK+R+L L L +I+ +F
Sbjct 327 SGYLNPQKSRILLQLCLYSGYGMDQIRSVF 356
>P0CX78 L-asparaginase 2-3 [Saccharomyces cerevisiae (strain ATCC
204508 / S288c)]
Length=362
Score = 178 bits (451), Expect = 4e-56
Identities = 115/330 (35%), Positives = 181/330 (55%), Gaps = 11/330 (3%)
Query 27 NVVVVATGGTIAGAGASSTNSATYTAAKVPVDALINAVPQIKDLANVSGIQALQIASESI 86
++ + TGGTIA G++S +A Y+ + V+ LI AVP + + AN+ +Q + S S+
Sbjct 34 SIKIFGTGGTIASKGSTSATTAGYSVG-LTVNDLIEAVPSLAEKANLDYLQVSNVGSNSL 92
Query 87 TDKELLSLARQVNDLVKKPSVNGVVITHGTDTLEETAFFLNLVIHTDKPIVLVGSMRPST 146
L+ L +++ + G V+THGTDT+EETAFFL+L I+++KP+ + G+MRP+T
Sbjct 93 NYTHLIPLYHGISEALASDDYAGAVVTHGTDTMEETAFFLDLTINSEKPVCIAGAMRPAT 152
Query 147 ALSADGPLNLYSAVALAASDEAKNKGVMVLMNDSIFAARDVTK-GINIHTNAFVSQWGEL 205
A SADGP+NLY AV++AAS+++ +G M+ +ND I + TK N + G L
Sbjct 153 ATSADGPMNLYQAVSIAASEKSLGRGTMITLNDRIASGFWTTKMNANSLDTFRADEQGYL 212
Query 206 GTLVEGKPYWFRSSVKRHTNASEFNIENIKG-DQLPLVQIVYGSDSMIPDAYLAYAK-AG 263
G ++ VK + F+I N+ ++P V I+Y + P+ + K G
Sbjct 213 GYFSNDDVEFYYPPVKPN-GWQFFDISNLTDPSEIPEVIILYSYQGLNPELIVKAVKDLG 271
Query 264 AKAIINAGTGNGSVGNYIVPTLKKLHDEQGIQIIRSSRVPQGFVLRNAEQPDDQYGWVVA 323
AK I+ AG+G GS ++L++E GI I+ S R G V PDD + +
Sbjct 272 AKGIVLAGSGAGSWTATGSIVNEQLYEEYGIPIVHSRRTADGTV-----PPDDAPEYAIG 326
Query 324 HD-LNPQKARLLAALALTKTNDAKEIQRMF 352
LNPQK+R+L L L +I+ +F
Sbjct 327 SGYLNPQKSRILLQLCLYSGYGMDQIRSVF 356
>P0CX77 L-asparaginase 2-2 [Saccharomyces cerevisiae (strain ATCC
204508 / S288c)]
Length=362
Score = 178 bits (451), Expect = 4e-56
Identities = 115/330 (35%), Positives = 181/330 (55%), Gaps = 11/330 (3%)
Query 27 NVVVVATGGTIAGAGASSTNSATYTAAKVPVDALINAVPQIKDLANVSGIQALQIASESI 86
++ + TGGTIA G++S +A Y+ + V+ LI AVP + + AN+ +Q + S S+
Sbjct 34 SIKIFGTGGTIASKGSTSATTAGYSVG-LTVNDLIEAVPSLAEKANLDYLQVSNVGSNSL 92
Query 87 TDKELLSLARQVNDLVKKPSVNGVVITHGTDTLEETAFFLNLVIHTDKPIVLVGSMRPST 146
L+ L +++ + G V+THGTDT+EETAFFL+L I+++KP+ + G+MRP+T
Sbjct 93 NYTHLIPLYHGISEALASDDYAGAVVTHGTDTMEETAFFLDLTINSEKPVCIAGAMRPAT 152
Query 147 ALSADGPLNLYSAVALAASDEAKNKGVMVLMNDSIFAARDVTK-GINIHTNAFVSQWGEL 205
A SADGP+NLY AV++AAS+++ +G M+ +ND I + TK N + G L
Sbjct 153 ATSADGPMNLYQAVSIAASEKSLGRGTMITLNDRIASGFWTTKMNANSLDTFRADEQGYL 212
Query 206 GTLVEGKPYWFRSSVKRHTNASEFNIENIKG-DQLPLVQIVYGSDSMIPDAYLAYAK-AG 263
G ++ VK + F+I N+ ++P V I+Y + P+ + K G
Sbjct 213 GYFSNDDVEFYYPPVKPN-GWQFFDISNLTDPSEIPEVIILYSYQGLNPELIVKAVKDLG 271
Query 264 AKAIINAGTGNGSVGNYIVPTLKKLHDEQGIQIIRSSRVPQGFVLRNAEQPDDQYGWVVA 323
AK I+ AG+G GS ++L++E GI I+ S R G V PDD + +
Sbjct 272 AKGIVLAGSGAGSWTATGSIVNEQLYEEYGIPIVHSRRTADGTV-----PPDDAPEYAIG 326
Query 324 HD-LNPQKARLLAALALTKTNDAKEIQRMF 352
LNPQK+R+L L L +I+ +F
Sbjct 327 SGYLNPQKSRILLQLCLYSGYGMDQIRSVF 356
>P0CZ17 L-asparaginase 2-1 [Saccharomyces cerevisiae (strain ATCC
204508 / S288c)]
Length=362
Score = 178 bits (451), Expect = 4e-56
Identities = 115/330 (35%), Positives = 181/330 (55%), Gaps = 11/330 (3%)
Query 27 NVVVVATGGTIAGAGASSTNSATYTAAKVPVDALINAVPQIKDLANVSGIQALQIASESI 86
++ + TGGTIA G++S +A Y+ + V+ LI AVP + + AN+ +Q + S S+
Sbjct 34 SIKIFGTGGTIASKGSTSATTAGYSVG-LTVNDLIEAVPSLAEKANLDYLQVSNVGSNSL 92
Query 87 TDKELLSLARQVNDLVKKPSVNGVVITHGTDTLEETAFFLNLVIHTDKPIVLVGSMRPST 146
L+ L +++ + G V+THGTDT+EETAFFL+L I+++KP+ + G+MRP+T
Sbjct 93 NYTHLIPLYHGISEALASDDYAGAVVTHGTDTMEETAFFLDLTINSEKPVCIAGAMRPAT 152
Query 147 ALSADGPLNLYSAVALAASDEAKNKGVMVLMNDSIFAARDVTK-GINIHTNAFVSQWGEL 205
A SADGP+NLY AV++AAS+++ +G M+ +ND I + TK N + G L
Sbjct 153 ATSADGPMNLYQAVSIAASEKSLGRGTMITLNDRIASGFWTTKMNANSLDTFRADEQGYL 212
Query 206 GTLVEGKPYWFRSSVKRHTNASEFNIENIKG-DQLPLVQIVYGSDSMIPDAYLAYAK-AG 263
G ++ VK + F+I N+ ++P V I+Y + P+ + K G
Sbjct 213 GYFSNDDVEFYYPPVKPN-GWQFFDISNLTDPSEIPEVIILYSYQGLNPELIVKAVKDLG 271
Query 264 AKAIINAGTGNGSVGNYIVPTLKKLHDEQGIQIIRSSRVPQGFVLRNAEQPDDQYGWVVA 323
AK I+ AG+G GS ++L++E GI I+ S R G V PDD + +
Sbjct 272 AKGIVLAGSGAGSWTATGSIVNEQLYEEYGIPIVHSRRTADGTV-----PPDDAPEYAIG 326
Query 324 HD-LNPQKARLLAALALTKTNDAKEIQRMF 352
LNPQK+R+L L L +I+ +F
Sbjct 327 SGYLNPQKSRILLQLCLYSGYGMDQIRSVF 356
Lambda K H a alpha
0.317 0.132 0.373 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1500576
Database: 97cac0d3b55e49f76bea111fd5405f91.SwissProt.fasta
Posted date: May 31, 2024 10:18 PM
Number of letters in database: 5,640
Number of sequences in database: 16
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
