BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 459afe0c64c4247e04f3f05f02fc2102.SwissProt.fasta
19 sequences; 9,933 total letters
Query= ACIAD2106
Length=484
Score E
Sequences producing significant alignments: (Bits) Value
Q5HNB2 2-succinylbenzoate--CoA ligase [Staphylococcus epidermidis... 105 2e-27
Q838K1 2-succinylbenzoate--CoA ligase [Enterococcus faecalis (str... 104 5e-27
P23971 2-succinylbenzoate--CoA ligase [Bacillus subtilis (strain ... 102 2e-26
Q5KVX9 2-succinylbenzoate--CoA ligase [Geobacillus kaustophilus (... 100 7e-26
C5D6U5 2-succinylbenzoate--CoA ligase [Geobacillus sp. (strain WC... 100 1e-25
Q8CS21 2-succinylbenzoate--CoA ligase [Staphylococcus epidermidis... 98.6 4e-25
A7GU88 2-succinylbenzoate--CoA ligase [Bacillus cytotoxicus (stra... 98.2 5e-25
Q9CHK3 2-succinylbenzoate--CoA ligase [Lactococcus lactis subsp. ... 97.8 6e-25
Q2YTP0 2-succinylbenzoate--CoA ligase [Staphylococcus aureus (str... 94.0 1e-23
B7JDD6 2-succinylbenzoate--CoA ligase [Bacillus cereus (strain AH... 93.6 2e-23
P9WQ37 Long-chain-fatty-acid--CoA ligase FadD13 [Mycobacterium tu... 90.9 1e-22
O53521 Long-chain-fatty-acid--CoA ligase FadD15 [Mycobacterium tu... 90.9 2e-22
O07610 Long-chain-fatty-acid--CoA ligase [Bacillus subtilis (stra... 84.0 3e-20
P96843 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-y... 77.8 2e-18
Q9S725 4-coumarate--CoA ligase 2 [Arabidopsis thaliana] 77.0 5e-18
Q55DR6 Fatty acyl-CoA synthetase A [Dictyostelium discoideum] 77.0 6e-18
Q9ULC5 Long-chain-fatty-acid--CoA ligase 5 [Homo sapiens] 77.0 6e-18
Q6ETN3 4-coumarate--CoA ligase 3 [Oryza sativa subsp. japonica] 76.3 9e-18
M4IQS1 Probable CoA ligase CCL10 [Humulus lupulus] 75.5 1e-17
>Q5HNB2 2-succinylbenzoate--CoA ligase [Staphylococcus epidermidis
(strain ATCC 35984 / RP62A)]
Length=474
Score = 105 bits (261), Expect = 2e-27
Identities = 108/460 (23%), Positives = 195/460 (42%), Gaps = 40/460 (9%)
Query 23 IALSDKYQTINYADLLSEVNKRQEILKQLDVKVVALYLENSVDLMLWDLTLLFSEIPTII 82
+A+ ++ Y +L E L L+ K + LY+ N +D ++ + I +
Sbjct 16 LAIVTNQLSLTYEELYHRAKTIAEYLTSLNQKRIGLYISNDIDSVVLIHACWLAHIEIAM 75
Query 83 LPPFFSSSQLNYCLEISQADLVISNDNLNLDHLDLY-FKDACFWRLKSAKAVEFP-QSTQ 140
+ + ++ + ++ L L+ +LY F D +F +S
Sbjct 76 INTRLTRHEMINQMNSVDIATIVHTLPLELEGFNLYHFNDLTQLDKHDVSGYKFNLESIA 135
Query 141 KLTFTSGTTGHPKAVCLGSEQILTVAKSLSEAIDETKPQKHLALMPLAVLLENIGCYAML 200
+ FTSGTTG KAV L AK +++ + L+++P+ + +
Sbjct 136 SIMFTSGTTGPQKAVPQTFNNHLASAKGCKQSLGFEQNTVWLSVLPIYHISGLSVILRAV 195
Query 201 YRGAQIELVSASDLGLRGASGVDVHQFSHYLNQSKPHSLI---LVPQFLSVLVEAVSSKL 257
G + LV Q L Q K + + LVPQ L L++A ++
Sbjct 196 IEGFTVRLVKK-------------FQTDDMLTQIKTYPITHMSLVPQTLKWLMDAGLTQP 242
Query 258 LRAEDYRFIAVGGGHVNPDLLKRAQTLNLPVYEGYGLSECASVVALNTP--AQQRAGSVG 315
E I +GG ++P L+++A T LPVY +G++E S +P ++R +VG
Sbjct 243 FSLEK---ILLGGAKLSPQLIEQALTYRLPVYNSFGMTETCSQFLTASPQMLKERFDTVG 299
Query 316 KPLAHVEVSIAN-----DGEILVANNQCLG------YLGSNHAPVKYWPTGDLGMLDEDG 364
KP +VEV I N GE+L+ + YL Y+ TGD+ +D++G
Sbjct 300 KPSENVEVKIKNPNAYGHGELLIKGENVMNGYLYPKYLKDTFDNDGYFQTGDIAEIDDEG 359
Query 365 YLYVHGRKKHQFITSFGRNVNPEWVEALLSQTGVVGQAFVYGEALPENYALLWPVHSAIS 424
Y+ ++ R+K I S G N+ P +E + + A G + ++ P+ ++
Sbjct 360 YVIIYDRRK-DLIISGGENIYPYQIETIAKDFEGIEDAVCVG--ISDDTWGQVPILYYVT 416
Query 425 NDQIEQ--VVEQANIKLPDYARVKHWVRLTE-PFSTTNQL 461
N I Q ++E L Y K + ++ P+++T +L
Sbjct 417 NQDINQTELIEHFENHLARYKIPKKYYQVKSLPYTSTGKL 456
>Q838K1 2-succinylbenzoate--CoA ligase [Enterococcus faecalis
(strain ATCC 700802 / V583)]
Length=485
Score = 104 bits (259), Expect = 5e-27
Identities = 121/455 (27%), Positives = 193/455 (42%), Gaps = 48/455 (11%)
Query 54 KVVALYLENSVDLMLWDLTLLFSEIPTIILPPFFSSSQLNYCLEISQADLVISNDNLNLD 113
K VAL+ +NS +L L L + L + ++L + L+ +Q +I
Sbjct 49 KRVALFSKNSKELYFSILALWELGKELLFLNTHLTLAELTFQLKDAQVKTIIGAPETQAL 108
Query 114 HLDLYFKDA--CFWRLKSAKAVEFPQ-----STQKLTFTSGTTGHPKAVCLGSEQILTVA 166
++ F D + S EF Q S + +TSGTTG PK V + L A
Sbjct 109 LEEISFVDVQPMIKKQHSLSHQEFQQPSDLESVASIMYTSGTTGQPKGVLQRFKNHLASA 168
Query 167 KSLSEAIDETKPQKHLALMPLAVLLENIGCYAMLYRGAQIELVSASDLGLRGASGVDVHQ 226
+ E + T L +PL + L G I L D Q
Sbjct 169 RGTQENMGITAEDCWLCAVPLFHISGLSIVVRQLVLGCSIRLYDK----------FDEQQ 218
Query 227 FSHYLNQSKPHSLILVPQFLSVLVEAVSSKLLRAEDYRFIAVGGGHVNPDLLKRAQTLNL 286
+ L + + + +V L L+ +V + + ++ + +GGG + PD L + + +
Sbjct 219 VTQDLQEGRGTVISVVATMLQQLL-SVYPEAGYSASFKGMLLGGGPIAPDKLAQCEEKGI 277
Query 287 PVYEGYGLSE-CASVVALN-TPAQQRAGSVGKPLAHVEVSIAND----------GEILVA 334
PV + YG++E C+ VVAL A + GS G+PL +++ I ++ GEIL+
Sbjct 278 PVIQSYGMTETCSQVVALKFEDAALKIGSAGQPLKDMQIKIVDELGQEQPEKQVGEILLK 337
Query 335 N-NQCLGYLGSNHAPVK-----YWPTGDLGMLDEDGYLYVHGRKKHQFITSFGRNVNPEW 388
N GYL + P K ++ TGD+G LD YLY+ R + I S G N+ P
Sbjct 338 GPNVVSGYL-NQRQPEKWTADGWFKTGDMGYLDAQSYLYLVSRLS-ELIISGGENIYPTE 395
Query 389 VEALLSQTGVVGQAFVYGEALPENYALLWPVHSAISNDQI--EQVVEQANIKLPDYARVK 446
VE +L + A V GE P+ PV IS+ +I Q+ +Q + KL Y R K
Sbjct 396 VEQVLQAITGIKAAAVVGE--PDAQWGAVPVAYVISDQEITLAQIQDQCSRKLAKYKRPK 453
Query 447 HWVRLTEPFSTTNQLATANGRLRRDEIVSRYHNVF 481
+ F TA+G++ + ++ F
Sbjct 454 R-IYFCHSFP-----QTASGKIAKHRFMTEEREAF 482
>P23971 2-succinylbenzoate--CoA ligase [Bacillus subtilis (strain
168)]
Length=486
Score = 102 bits (254), Expect = 2e-26
Identities = 120/479 (25%), Positives = 203/479 (42%), Gaps = 60/479 (13%)
Query 20 PYNIALSDKYQTINYADLLSEVNKRQEILKQLDVK---VVALYLENSVDLMLWDLTLLFS 76
P IAL + QT+ +A+L + + E L V+ A+ L+N +++
Sbjct 17 PERIALIYEDQTVTFAELFAASKRMAEQLAAHSVRKGDTAAILLQNRAEMVYAVHACFLL 76
Query 77 EIPTIILPPFFSSSQLNYCLEISQADLVISNDNLNLDHLDLYFKDACFWRLKSAKAVEFP 136
+ ++L S+ + + LE S + ++++ + + + L A E
Sbjct 77 GVKAVLLNTKLSTHERLFQLEDSGSGFLLTDSSFEKKEYEHIVQTIDVDELMKEAAEEIE 136
Query 137 -------QSTQKLTFTSGTTGHPKAV--CLGSEQILTVAKSLSEAIDETKPQKHLALMPL 187
+T L +TSGTTG PK V G+ V+ +L+ I T+ + L +PL
Sbjct 137 IEAYMQMDATATLMYTSGTTGKPKGVQQTFGNHYFSAVSSALNLGI--TEQDRWLIALPL 194
Query 188 AVLLENIGCYAMLYRGAQIELVSASDLGLRGASGVDVHQFSHYLNQSKPHSLILVPQFLS 247
+ + + G + L V H +N+ + + V L+
Sbjct 195 FHISGLSALFKSVIYGMTVVLHQR----------FSVSDVLHSINRHEVTMISAVQTMLA 244
Query 248 VLVEAVSSKLLRAEDYRFIAVGGGHVNPDLLKRAQTLNLPVYEGYGLSE-CASVVALNTP 306
L+E + E R I +GGG LL+ + PV++ YG++E C+ +V L+
Sbjct 245 SLLEETNRC---PESIRCILLGGGPAPLPLLEECREKGFPVFQSYGMTETCSQIVTLSPE 301
Query 307 -AQQRAGSVGKPLAHVEVSIAND---------GEILVAN-NQCLGYL---GSNHAPVK-- 350
+ ++ GS GKPL E+ I D GEI+V N Y +N A +
Sbjct 302 FSMEKLGSAGKPLFSCEIKIERDGQVCEPYEHGEIMVKGPNVMKSYFNRESANEASFQNG 361
Query 351 YWPTGDLGMLDEDGYLYVHGRKKHQFITSFGRNVNPEWVEALLSQTGVVGQAFVYGE--- 407
+ TGDLG LD +G+LYV R+ I S G N+ P VE++L V +A V G
Sbjct 362 WLKTGDLGYLDNEGFLYVLDRRS-DLIISGGENIYPAEVESVLLSHPAVAEAGVSGAEDK 420
Query 408 ---ALPENYALLWPVHSAISNDQIEQVVEQ--ANIKLPDYARVKHWVRLTEPFSTTNQL 461
+P Y +L H +S ++ ++ A K+P K +V P + +N+L
Sbjct 421 KWGKVPHAYLVL---HKPVSAGELTDYCKERLAKYKIP----AKFFVLDRLPRNASNKL 472
>Q5KVX9 2-succinylbenzoate--CoA ligase [Geobacillus kaustophilus
(strain HTA426)]
Length=490
Score = 100 bits (250), Expect = 7e-26
Identities = 117/435 (27%), Positives = 189/435 (43%), Gaps = 66/435 (15%)
Query 12 LENYQFQQPYNIALSDKYQTINYADLLSEVNKRQEILKQLDVK---VVALYLENSVDLML 68
L+ F P IA+SD +T +A+L L Q VK +VAL ++N ++++
Sbjct 8 LKQRAFLTPERIAVSDGRRTKTFAELYEAAAVWARRLAQAGVKEGDIVALLMKNRIEMIE 67
Query 69 WDLTLLFSEIPTIILPPFFSSSQLNYCLEISQADLVISNDNLN----------------- 111
L F ++ +S +L + L+ S A L I+++ L
Sbjct 68 IIHALFFLGARVLLQNVRLTSYELGWQLDDSGARLAIADEELAGSLDGDGRVLTVGAVAA 127
Query 112 LDHLDLYFKDACFWRLKSAKAVEFPQSTQKLTFTSGTTGHPKAVC--LGSEQILTVAKSL 169
L +D+ K+ C + + +TSGTTG PK V G+ V +L
Sbjct 128 LPEVDVSLKETCDL-----------EEVATIMYTSGTTGTPKGVLQTYGNHWWSAVGSAL 176
Query 170 SEAIDETKPQKHLALMPLAVLLE-NIGCYAMLYRGAQIELVSASDLGLRGASGVDVHQFS 228
+ + E LA +PL + +I +++Y + +R + D + +
Sbjct 177 NLGLHER--DCWLAAVPLFHISGLSIAMRSVIY-----------GMPMRLQTSFDPKEAN 223
Query 229 HYLNQSKPHSLILVPQFLSVLVEAVSSKLLRAEDYRFIAVGGGHVNPDLLKRAQTLNLPV 288
++ + + +V L +V A + + +R + +GGG LL+ + +PV
Sbjct 224 EWIMRGDVTIMSVVAAMLQRMV-AELGEARYPDTFRCMLLGGGPAPRPLLEACKEKGIPV 282
Query 289 YEGYGLSECASVVALNTP--AQQRAGSVGKPLAHVEVSIAND---------GEILVAN-N 336
Y+ YG++E AS +A P + + GS GKPL E+ I D GEI+V N
Sbjct 283 YQTYGMTETASQIATLAPEYSLTKLGSAGKPLFPAELCILKDGKPAAPHEAGEIVVKGPN 342
Query 337 QCLGYLGSNHAPVK-----YWPTGDLGMLDEDGYLYVHGRKKHQFITSFGRNVNPEWVEA 391
GY A + ++ TGD+G LDEDG+LYV R+ I S G NV P VEA
Sbjct 343 VTKGYWQRPEATAQAIRGGWFFTGDIGYLDEDGFLYVLDRRS-DLIISGGENVYPAEVEA 401
Query 392 LLSQTGVVGQAFVYG 406
+L V +A V G
Sbjct 402 VLLSHPDVEEAGVTG 416
>C5D6U5 2-succinylbenzoate--CoA ligase [Geobacillus sp. (strain
WCH70)]
Length=492
Score = 100 bits (248), Expect = 1e-25
Identities = 111/423 (26%), Positives = 185/423 (44%), Gaps = 52/423 (12%)
Query 17 FQQPYNIALSDKYQTINYADLLSEVNKRQEILKQLDVK---VVALYLENSVDLMLWDLTL 73
F P IA+ D + +L V KR L V+ +VA++++NSV ++ L
Sbjct 14 FLTPERIAVYDGQGKKTFMELHESVMKRARQLANTGVRKGDIVAIFMKNSVAMIECIHAL 73
Query 74 LFSEIPTIILPPFFSSSQLNYCLEISQADLVISNDNLNLDHLDLYFKDACFWRLKSA--K 131
+ ++ +S +L + L+ S A VI++D L D ++ + L + +
Sbjct 74 HYIGAIVLLQNTRLTSHELAWQLKDSGAVYVIADDEL-ADRIEGNIRVITMSELSALPEE 132
Query 132 AVEFPQ-----STQKLTFTSGTTGHPKAVCLGSEQILTVAKSLSEAIDETKPQKHLALMP 186
VEF Q + +TSGTTG PK V E A + + + LA +P
Sbjct 133 NVEFQQYYHFDDIATIMYTSGTTGKPKGVLQTYENHWWSAIGSALNLGLNENDCWLAAVP 192
Query 187 ------LAVLLENIGCYAMLYRGAQIELVSASDLGLRGASGVDVHQFSHYLNQSKPHSLI 240
L++++ ++ +Y + A++L + G K +
Sbjct 193 FFHISGLSIMMRSVIYGMSMYVMRAFDAKKANELIIGG----------------KVTIMS 236
Query 241 LVPQFLSVLVEAVSSKLLRAEDYRFIAVGGGHVNPDLLKRAQTLNLPVYEGYGLSECASV 300
+V L ++ + + E +R + +GGG LL+ + +PVY+ YG++E AS
Sbjct 237 VVSAMLQKMIADLGERRY-PETFRCMLLGGGPAPKPLLEVCKAKGIPVYQTYGMTETASQ 295
Query 301 VALNTP--AQQRAGSVGKPLAHVEVSIANDGE----------ILVANNQCLGYLGSNHAP 348
+A P + + GS GKPL ++ I DG+ ++ N GYL A
Sbjct 296 IATLAPEYSLTKLGSAGKPLFPSQLRIEKDGQVARPYEPGEIVVKGPNVTKGYLHRPDAT 355
Query 349 VK-----YWPTGDLGMLDEDGYLYVHGRKKHQFITSFGRNVNPEWVEALLSQTGVVGQAF 403
K ++ TGD+G +DEDG+LYV R+ I S G NV P +EA+L V +A
Sbjct 356 AKAIRGGWFYTGDIGYIDEDGFLYVLDRRS-DLIISGGENVYPAEIEAVLLSHEAVEEAG 414
Query 404 VYG 406
V G
Sbjct 415 VTG 417
>Q8CS21 2-succinylbenzoate--CoA ligase [Staphylococcus epidermidis
(strain ATCC 12228 / FDA PCI 1200)]
Length=474
Score = 98.6 bits (244), Expect = 4e-25
Identities = 105/460 (23%), Positives = 193/460 (42%), Gaps = 40/460 (9%)
Query 23 IALSDKYQTINYADLLSEVNKRQEILKQLDVKVVALYLENSVDLMLWDLTLLFSEIPTII 82
+A+ ++ Y +L + L L+ K + LY+ N +D ++ + I +
Sbjct 16 LAIVTNQLSLTYEELYHRAKTIAQYLTSLNQKRIGLYISNDIDSVVLIHACWLAHIEIAM 75
Query 83 LPPFFSSSQLNYCLEISQADLVISNDNLNLDHLDLY-FKDACFWRLKSAKAVEFP-QSTQ 140
+ + ++ + ++ L L+ +LY F D +F +S
Sbjct 76 INTRLTRHEMINQMNSVDIATIVHTLPLELEGFNLYHFNDLTQLDKHDVSGYKFNLESIA 135
Query 141 KLTFTSGTTGHPKAVCLGSEQILTVAKSLSEAIDETKPQKHLALMPLAVLLENIGCYAML 200
+ FTSGTTG KAV L AK +++ + L+++P+ + +
Sbjct 136 SIMFTSGTTGPQKAVPQTFNNHLASAKGCKQSLGFEQNTVWLSVLPIYHISGLSVILRAV 195
Query 201 YRGAQIELVSASDLGLRGASGVDVHQFSHYLNQSKPHSLI---LVPQFLSVLVEAVSSKL 257
G + LV Q L Q K + + LVPQ L L++A ++
Sbjct 196 IEGFTVRLVKK-------------FQTDDMLTQIKTYPITHMSLVPQTLKWLMDAGLTQP 242
Query 258 LRAEDYRFIAVGGGHVNPDLLKRAQTLNLPVYEGYGLSECASVVALNTP--AQQRAGSVG 315
E I +GG ++P L+++A LPVY +G++E S +P ++R +VG
Sbjct 243 FSLEK---ILLGGAKLSPQLIEQAFAYRLPVYNSFGMTETCSQFLTASPQMLKERFDTVG 299
Query 316 KPLAHVEVSIAN-----DGEILVANNQCLG------YLGSNHAPVKYWPTGDLGMLDEDG 364
K +VEV I N GE+L+ + YL Y+ TGD+ +D++G
Sbjct 300 KTSENVEVKIKNPNAYGHGELLIKGENVMNGYLYPKYLKDTFDNDGYFQTGDIAEIDDEG 359
Query 365 YLYVHGRKKHQFITSFGRNVNPEWVEALLSQTGVVGQAFVYGEALPENYALLWPVHSAIS 424
Y+ ++ R+K I S G N+ P +E + + A G + ++ P+ ++
Sbjct 360 YVIIYDRRK-DLIISGGENIYPYQIETIAKDFEGIEDAVCVG--ISDDTWGQVPILYYVT 416
Query 425 NDQIEQ--VVEQANIKLPDYARVKHWVRLTE-PFSTTNQL 461
N I Q ++E L Y K + ++ P+++T +L
Sbjct 417 NQDINQNELIEHFENHLARYKIPKKYYQVESLPYTSTGKL 456
>A7GU88 2-succinylbenzoate--CoA ligase [Bacillus cytotoxicus (strain
DSM 22905 / CIP 110041 / 391-98 / NVH 391-98)]
Length=481
Score = 98.2 bits (243), Expect = 5e-25
Identities = 119/460 (26%), Positives = 210/460 (46%), Gaps = 57/460 (12%)
Query 17 FQQPYNIALSDKYQTINYADLLSEVNKRQEILKQLDVKV---VALYLENSVDLMLWDLTL 73
F P IA+ K + I + L +V E L L +K VA+ ++N ++++ L
Sbjct 13 FLTPDRIAIETKEEKITFFALHEKVVSVCENLAYLQIKKGQKVAVLMKNGMEMIAVIHAL 72
Query 74 LFSEIPTIILPPFFSSSQLNYCLEISQADLVISNDNLNLDHLDLYFKDACFWRLKSAKAV 133
+ ++L S +L + +E ++ ++++ + + +Y + K + +
Sbjct 73 SYIGAIAVLLNTRLSREELLWQMEDAEVICLLTDQIFEPEQVPVYTFEEVENGPKQSVVI 132
Query 134 EFPQSTQK---LTFTSGTTGHPKAVCL--GSEQILTVAKSLSEAIDETKPQKHLALMP-- 186
+ S + + +TSGTTG PK V L G+ V SL+ + + LA MP
Sbjct 133 QEEFSLAEAMTIIYTSGTTGKPKGVILTYGNHWASAVGSSLNLGLRDD--DCWLACMPMF 190
Query 187 ----LAVLLENIGCYAMLYRGAQIELVSASDLGLRGASGVDVHQFSHYLNQSKPHSLI-L 241
L++L++NI +Y G ++ LV D F H Q+K ++I +
Sbjct 191 HVGGLSLLMKNI-----MY-GMRVLLVPKYD-----------PDFIHQAIQTKGVTIISV 233
Query 242 VPQFLSVLVEAVSSKLLRAEDYRFIAVGGGHVNPDLLKRAQTLNLPVYEGYGLSECASVV 301
V + L+ L+E + ++ + R + +GGG LL+ +PVY+ YG++E +S +
Sbjct 234 VAKMLTDLLERLGNETYPSS-LRCMLLGGGPAPKPLLEACVQKGIPVYQTYGMTETSSQI 292
Query 302 ALNTPAQQ--RAGSVGKPLAHVEVSIANDGEILVAN----------NQCLGYLGSNHAP- 348
+ + GS GKPL ++ I DG+++ AN N GY A
Sbjct 293 CTLSADYMLTKVGSAGKPLFPCQLRIEKDGKVMPANVEGEIVVKGPNVTRGYFKREDATR 352
Query 349 ---VKYW-PTGDLGMLDEDGYLYVHGRKKHQFITSFGRNVNPEWVEALLSQTGVVGQAFV 404
V W TGDLG +D++G+LYV R+ I S G N+ P +E +L +V +A V
Sbjct 353 ETIVDGWLHTGDLGYVDDEGFLYVLDRRS-DLIISGGENIYPAQIEEVLLSHPLVLEAGV 411
Query 405 YGEALPENYALLWPVHSAISNDQI--EQVVEQANIKLPDY 442
G++ E + + PV + Q+ E+++ KL Y
Sbjct 412 VGKS-DETWGQV-PVAFVVKAGQVTEEEMIHFCEEKLAKY 449
>Q9CHK3 2-succinylbenzoate--CoA ligase [Lactococcus lactis subsp.
lactis (strain IL1403)]
Length=451
Score = 97.8 bits (242), Expect = 6e-25
Identities = 102/377 (27%), Positives = 167/377 (44%), Gaps = 38/377 (10%)
Query 34 YADLLSEVNKRQEILKQL--DVKVVALYLENSVDLMLWDLTLLFSEIPTIILPPFFSSSQ 91
+A + EVNK E L L + VAL ENSV++ + LL ++L + +
Sbjct 22 FAQINQEVNKMAEHLAPLIDNQSRVALLSENSVEMAVVLFALLGLSKEVLLLNRHLTEYE 81
Query 92 LNYCLEISQADLVISNDNL------NLDHLDLYFKDACFWRLKSAKAVEFP-QSTQKLTF 144
L ++ + D V ++D L ++ +++ + C L + +FP + +
Sbjct 82 LADQIKELKIDKVFTSDLLTEKVTDSISFSEIWTSNPCPVSLSA----DFPDEKIAVIMN 137
Query 145 TSGTTGHPKAVCLGSEQILTVAKSLSEAIDETKPQKHLALMPLAVLLENIGCYAMLYRGA 204
TS TTG K+V + I K+ E + L ++P+ + LY
Sbjct 138 TSATTGKFKSVPITWGMISNHVKASKETLGAYDNDNWLVILPMFHVSGLSIIMRTLYNAT 197
Query 205 QIELVSASDLGLRGASGVDVHQFSHYLNQSKPHSLILVPQFLSVLVEAVSSKLLRAEDYR 264
+V D +Q +N K + + LVP L+ + + + S LR
Sbjct 198 SATVVDK----------FDENQLLEMINSGKINMVSLVPTLLTRIADKLHSNNLR----- 242
Query 265 FIAVGGGHVNPDLLKRAQTLNLPVYEGYGLSE--CASVVALNTPAQQRAGSVGKPLAHVE 322
I +GG + L+K+ Q L LP+Y+ YG++E SV + SVG+PL VE
Sbjct 243 LILLGGEFIPQPLIKKCQELGLPIYKTYGMTESFSQSVTFNILDFPDKTSSVGRPLPGVE 302
Query 323 VSI-----ANDGEILVANNQCL-GYLGSNHAPVKYWPTGDLGMLDEDGYLYVHGRKKHQF 376
+ I A GEI + + + YLG + TGD+G LD DG+LY+ R+K
Sbjct 303 IEIRQADLAGVGEIWLKSPMLMKAYLGQKPYGTAF-ETGDIGYLDTDGFLYLLNRRK-DI 360
Query 377 ITSFGRNVNPEWVEALL 393
I S G N+ P+ +E L+
Sbjct 361 IISGGENIYPKEIEDLV 377
>Q2YTP0 2-succinylbenzoate--CoA ligase [Staphylococcus aureus
(strain bovine RF122 / ET3-1)]
Length=492
Score = 94.0 bits (232), Expect = 1e-23
Identities = 121/493 (25%), Positives = 214/493 (43%), Gaps = 68/493 (14%)
Query 18 QQPYNIALSDKYQTINYADLLSEVNKRQEILKQLDVKVVALYLENSVDLML-----WDLT 72
Q ++IA++D ++ Y +L E + + LK V LY++NS+ ++ W
Sbjct 11 QNGHHIAITDGQESYTYQNLYCEASLLAKRLKAYQQSRVGLYIDNSIQSIILIHACWLAN 70
Query 73 LLFSEIPTIILPPFFSSS------QLNYC---LEISQADLVISND----------NLNLD 113
+ + I T + P + QL +C LE+ +V+ +D N LD
Sbjct 71 IEIAMINTRLTPNEMKNQMRSIDVQLIFCTLPLELRGFQIVLLDDIEFAGRDITMNGLLD 130
Query 114 H-LDLYF---------KDACFWRLKSAKAVEFPQSTQKLTFTSGTTGHPKAVCLGSEQIL 163
+ +D+ + KD+ L ++ ++ + FTSGTTG KAV
Sbjct 131 NTMDIQYDTSNETVVPKDSPSNILNTSFNLD---DIASIMFTSGTTGPQKAVPQTFRNHY 187
Query 164 TVAKSLSEAIDETKPQKHLALMPLAVLLENIGCYAMLYRGAQIELVSASDLGLRGASGVD 223
A E++ + L+++P+ +I ++L R A IE +R +
Sbjct 188 ASAIGCKESLGFDRDTNWLSVLPIY----HISGLSVLLR-AVIE-----GFTVRIVDKFN 237
Query 224 VHQFSHYLNQSKPHSLILVPQFLSVLVEAVSSKLLRAEDYRFIAVGGGHVNPDLLKRAQT 283
Q + + + LVPQ L+ L++ L D + I +GG ++ +++ A
Sbjct 238 AEQILTMIKNERITHISLVPQTLNWLMQ---QGLHEPYDLQKILLGGAKLSATMIETALQ 294
Query 284 LNLPVYEGYGLSECASVVALNTP--AQQRAGSVGKPLAHVEVSIAN-----DGEILVAN- 335
NLP+Y +G++E S TP R +VG P A+V+V I N GE+++
Sbjct 295 YNLPIYNSFGMTETCSQFLTATPQMLHARPDTVGMPSANVDVKIKNPNKEGHGELMIKGA 354
Query 336 NQCLGYLGSNHAPVK----YWPTGDLGMLDEDGYLYVHGRKKHQFITSFGRNVNPEWVEA 391
N GYL Y+ TGD+ +D +GY+ ++ R+K I S G N+ P +E
Sbjct 355 NVMNGYLYPTDLTGTFENGYFNTGDIAEIDYEGYVMIYDRRK-DLIISGGENIYPYQIET 413
Query 392 LLSQTGVVGQAFVYGEALPENYALLWPVHSAISNDQIE--QVVEQANIKLPDYARVKHWV 449
+ Q + A G P++ P +S I Q++ + L Y KH+
Sbjct 414 VAKQFPGISDAVCVGH--PDDTWGQVPKLYFVSESDISKAQLIAYLSQHLAKYKIPKHFE 471
Query 450 RL-TEPFSTTNQL 461
++ T P+++T +L
Sbjct 472 KVDTLPYTSTGKL 484
>B7JDD6 2-succinylbenzoate--CoA ligase [Bacillus cereus (strain
AH820)]
Length=482
Score = 93.6 bits (231), Expect = 2e-23
Identities = 111/427 (26%), Positives = 192/427 (45%), Gaps = 53/427 (12%)
Query 12 LENYQFQQPYNIALSDKYQTINYADLLSEVNKRQEILKQLDVK---VVALYLENSVDLML 68
L+ F P A+ + + + + L +V E L + VK VA+ ++N ++++
Sbjct 9 LKQRAFLTPDRTAIEIEEEKVTFMQLHEKVVSVCEHLTHVGVKRGQKVAVLMKNGIEMIT 68
Query 69 WDLTLLFSEIPTIILPPFFSSSQLNYCLEISQADLVISNDNLNLDHLDLY-FKDACFWRL 127
L ++ ++L S +L + ++ ++ ++++ + + +Y F +
Sbjct 69 VIHALSYAGAVAVLLNTRLSREELLWQMDDAEVICLVTDQDFEAKDIPVYSFAEVMNGPK 128
Query 128 KSAKAVEFPQSTQKLT--FTSGTTGHPKAVCL--GSEQILTVAKSLSEAIDETKPQKHLA 183
+ A E + +T +TSGTTG PK V L G+ V SL+ + + LA
Sbjct 129 EEASIQEEFSLREAMTIIYTSGTTGKPKGVILTYGNHWASAVGSSLNLGLRDD--DCWLA 186
Query 184 LMP------LAVLLENIGCYAMLYRGAQIELVSASDLGLRGASGVDVHQFSHYLNQSKPH 237
MP L++L++NI +Y G +I LV D F H Q++
Sbjct 187 CMPMFHVGGLSLLMKNI-----MY-GMRILLVPKYDA-----------DFIHKALQTRGV 229
Query 238 SLI-LVPQFLSVLVEAVSSKLLRAEDYRFIAVGGGHVNPDLLKRAQTLNLPVYEGYGLSE 296
++I +V + L+ L+E + + R + +GGG LL+ +PVY+ YG++E
Sbjct 230 TIISVVSKMLTDLLERLGEGTYPSS-LRCMLLGGGPAPKPLLETCVDKGIPVYQTYGMTE 288
Query 297 CASVVALNTPAQQ--RAGSVGKPLAHVEVSIANDG---------EILVAN-NQCLGYLGS 344
+S + + + GS GKPL ++ I DG EI+V N GY
Sbjct 289 TSSQICTLSADYMLTKVGSAGKPLFQCQLRIEKDGVVVPPFAEGEIVVKGPNVTGGYFNR 348
Query 345 NHAPVK-----YWPTGDLGMLDEDGYLYVHGRKKHQFITSFGRNVNPEWVEALLSQTGVV 399
A + + TGDLG LDE+G+LYV R+ I S G N+ P +E +L +V
Sbjct 349 EDATRETIQNGWLHTGDLGYLDEEGFLYVLDRRS-DLIISGGENIYPAQIEEVLLSHPMV 407
Query 400 GQAFVYG 406
+A V G
Sbjct 408 AEAGVVG 414
>P9WQ37 Long-chain-fatty-acid--CoA ligase FadD13 [Mycobacterium
tuberculosis (strain ATCC 25618 / H37Rv)]
Length=503
Score = 90.9 bits (224), Expect = 1e-22
Identities = 86/330 (26%), Positives = 146/330 (44%), Gaps = 51/330 (15%)
Query 142 LTFTSGTTGHPKAVCLGSEQILTVAKSLSEAIDETKPQKHLALMPLAVLLENIGCYAMLY 201
+ +TSGTTGHPK V E + + A S + ID + L +P ++
Sbjct 161 IMYTSGTTGHPKGVVHTHESVHSAASSWASTIDVRYRDRLLLPLP-------------MF 207
Query 202 RGAQIELVSASDLGLRGASGVDVHQFSHYLNQSKPHSLIL---------VPQFLSVLVEA 252
A + V S +RG + + + QF + +K SLI+ VP L+ + +
Sbjct 208 HVAALTTVIFS--AMRGVTLISMPQF----DATKVWSLIVEERVCIGGAVPAILNFMRQV 261
Query 253 VSSKLLRAEDYRFIAVGGGHVNPDLLKRAQTLNLPVYEGYGLSEC--ASVVALNTPAQQR 310
L A D+R+ GG + L+K N+ V +GY L+E + L+ A ++
Sbjct 262 PEFAELDAPDFRYFITGGAPMPEALIKIYAAKNIEVVQGYALTESCGGGTLLLSEDALRK 321
Query 311 AGSVGKPLAHVEVSIANDGEILVANNQCLGYLGSNHAPVKYW---------------PTG 355
AGS G+ +V++ D ++ + + + S+ +YW TG
Sbjct 322 AGSAGRATMFTDVAVRGDDGVIREHGEGEVVIKSDILLKEYWNRPEATRDAFDNGWFRTG 381
Query 356 DLGMLDEDGYLYVHGRKKHQFITSFGRNVNPEWVEALLSQTGVVGQAFVYGEALP-ENYA 414
D+G +D++GYLY+ R K I S G NV P +E+++ GV G + V LP E +
Sbjct 382 DIGEIDDEGYLYIKDRLK-DMIISGGENVYPAEIESVI--IGVPGVSEVAVIGLPDEKWG 438
Query 415 LLWPVHSAISNDQI--EQVVEQANIKLPDY 442
+ +++ +Q+VE +L Y
Sbjct 439 EIAAAIVVADQNEVSEQQIVEYCGTRLARY 468
>O53521 Long-chain-fatty-acid--CoA ligase FadD15 [Mycobacterium
tuberculosis (strain ATCC 25618 / H37Rv)]
Length=600
Score = 90.9 bits (224), Expect = 2e-22
Identities = 89/333 (27%), Positives = 131/333 (39%), Gaps = 71/333 (21%)
Query 142 LTFTSGTTGHPKAVCLGSEQILTVAKSLSEAIDET---KPQKHLALMPLAVLLENIGCYA 198
L +TSGTTG PK L ++ K + A T K ++ L +PLA +L A
Sbjct 186 LIYTSGTTGRPKGCQLTQSNLVHEIKG-ARAYHPTLLRKGERLLVFLPLAHVLARAISMA 244
Query 199 MLYRGAQIELVSASDLGLRGASGVDVHQFSHYLNQSKPHSLILVPQFLSVLVEAVSSKLL 258
+ + S D+ L KP ++ VP+ +
Sbjct 245 AFHSKVTVGFTS------------DIKNLLPMLAVFKPTVVVSVPRVFEKVYNTAEQNAA 292
Query 259 RAEDYRFIAVGGGHV----------NPDLLKRAQTL------------------------ 284
A R A+ P LL RA+
Sbjct 293 NAGKGRIFAIAAQTAVDWSEACDRGGPGLLLRAKHAVFDRLVYRKLRAALGGNCRAAVSG 352
Query 285 ---------------NLPVYEGYGLSECASVVALNTPAQQRAGSVGKPLAHVEVSIANDG 329
L +YEGYGLS + VA++ + G+VGKP+ + IA+DG
Sbjct 353 GAPLGARLGHFYRGAGLTIYEGYGLSGTSGGVAISQFNDLKIGTVGKPVPGNSLRIADDG 412
Query 330 EILVANNQCL-GYLGSNHAPVK-----YWPTGDLGMLDEDGYLYVHGRKKHQFITSFGRN 383
E+LV GY + A + ++ TGDLG +DEDG+L + GRKK +T+ G+N
Sbjct 413 ELLVRGGVVFSGYWRNEQATTEAFTDGWFKTGDLGAVDEDGFLTITGRKKEIIVTAGGKN 472
Query 384 VNPEWVEALLSQTGVVGQAFVYGEALPENYALL 416
V P +E L ++ QA V G+A P AL+
Sbjct 473 VAPAVLEDQLRAHPLISQAVVVGDAKPFIGALI 505
>O07610 Long-chain-fatty-acid--CoA ligase [Bacillus subtilis (strain
168)]
Length=513
Score = 84.0 bits (206), Expect = 3e-20
Identities = 116/490 (24%), Positives = 196/490 (40%), Gaps = 82/490 (17%)
Query 10 SKLENYQFQQPYNIALSDKYQTINYADLLSEVNKRQEILKQLDVKV---VALYLENSVDL 66
SKLE ++P +IA K + Y +L + + + L++ ++ +AL L NS D
Sbjct 5 SKLEETASEKPDSIACRFKDHMMTYQELNEYIQRFADGLQEAGMEKGDHLALLLGNSPDF 64
Query 67 MLWDLTLLFSEIPTIILPPFFSSSQLNYCLEISQADLVISNDNL---------NLDHLDL 117
++ L + I + + P ++ +++ Y L ++ L +L ++L
Sbjct 65 IIAFFGALKAGIVVVPINPLYTPTEIGYMLTNGDVKAIVGVSQLLPLYESMHESLPKVEL 124
Query 118 YF------------------KDACFWRL----KSAKAVE--FPQSTQKLTFTSGTTGHPK 153
K F ++ +AK + P T + +TSGTTG PK
Sbjct 125 VILCQTGEAEPEAADPEVRMKMTTFAKILRPTSAAKQNQEPVPDDTAVILYTSGTTGKPK 184
Query 154 AVCLGSEQILTVAKSLSE--AIDETKPQKHLALMPLAVLLENIGCYAMLYRGAQIELVSA 211
L + + + A ++ +DE +N+ C ++ + +
Sbjct 185 GAMLTHQNLYSNANDVAGYLGMDER---------------DNVVCALPMFHVFCLTVCMN 229
Query 212 SDLGLRGASGVDVHQFS-----HYLNQSKPHSLILVPQFLSVLVEAVSSKLLRAEDYRFI 266
+ L + GA+ + QFS + Q + VP + L + + K R
Sbjct 230 APL-MSGATVLIEPQFSPASVFKLVKQQQATIFAGVPTMYNYLFQHENGKKDDFSSIRLC 288
Query 267 AVGGGHVNPDLLKR-AQTLNLPVYEGYGLSECASVVALNT-PAQQRAGSVGKPLAHVEVS 324
GG + LL + + + EGYGLSE + V N ++ GS+G + HVE
Sbjct 289 ISGGASMPVALLTAFEEKFGVTILEGYGLSEASPVTCFNPFDRGRKPGSIGTSILHVENK 348
Query 325 IAND----------GEILVAN-NQCLGY----LGSNHAPVKYWP-TGDLGMLDEDGYLYV 368
+ + GE++V N GY + + HA W TGDL DEDGY Y+
Sbjct 349 VVDPLGRELPAHQVGELIVKGPNVMKGYYKMPMETEHALKDGWLYTGDLARRDEDGYFYI 408
Query 369 HGRKKHQFITSFGRNVNPEWVEALLSQTGVVGQAFVYGEALPEN----YALLWPVHSAIS 424
RKK I G NV P VE +L V +A V G P++ + P S ++
Sbjct 409 VDRKKDMIIVG-GYNVYPREVEEVLYSHPDVKEAVVIGVPDPQSGEAVKGYVVPKRSGVT 467
Query 425 NDQIEQVVEQ 434
+ I Q E+
Sbjct 468 EEDIMQHCEK 477
>P96843 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl:CoA
ligase [Mycobacterium tuberculosis (strain
ATCC 25618 / H37Rv)]
Length=507
Score = 77.8 bits (190), Expect = 2e-18
Identities = 82/288 (28%), Positives = 123/288 (43%), Gaps = 32/288 (11%)
Query 136 PQSTQKLTFTSGTTGHPKAVCLGSEQILTVAKSLSEAIDETKPQKHLALMPLAVLLENIG 195
PQ + FTSGTTG K V Q L+ + S + T ++L + P N G
Sbjct 168 PQDVSDILFTSGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINP---FFHNFG 224
Query 196 CYAMLYRGAQIELVSASDLGLRGASGVDVHQFS--HYLNQSKPHSLILV---PQFLSVLV 250
A + Q GA+ + F H L + H + ++ P L+
Sbjct 225 YKAGILACLQ-----------TGATLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLL 273
Query 251 EAVSSKLLRAEDYRFIAVGGGHVNPDLLKRAQT-LNLP-VYEGYGLSECASVVALNTP-- 306
+ + K RF G V L++R Q+ L++ V YGL+E + + P
Sbjct 274 DHPARKDFDLSSLRFAVTGAATVPVVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPED 333
Query 307 -AQQRAGSVGKPLAHVEVSIANDGEILVAN-NQCLGYLGSNHAPVK------YWPTGDLG 358
A A + G+P A E+ IA+DGE+L+ N +GYL A + TGD+G
Sbjct 334 DAVTVATTCGRPFADFELRIADDGEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIG 393
Query 359 MLDEDGYLYVHGRKKHQFITSFGRNVNPEWVEALLSQTGVVGQAFVYG 406
+D+ G L + R K +I G NV P VE +L++ V A V G
Sbjct 394 AVDQAGNLRITDRLKDMYICG-GFNVYPAEVEQVLARMDGVADAAVIG 440
>Q9S725 4-coumarate--CoA ligase 2 [Arabidopsis thaliana]
Length=556
Score = 77.0 bits (188), Expect = 5e-18
Identities = 119/516 (23%), Positives = 211/516 (41%), Gaps = 91/516 (18%)
Query 30 QTINYADLLSEVNKRQEILKQLDVK---VVALYLENSVDLMLWDLTLLFSEIPTIILPPF 86
+ YAD+ K L L VK VV + L NS +++L L F T PF
Sbjct 62 EVYTYADVHVTSRKLAAGLHNLGVKQHDVVMILLPNSPEVVLTFLAASFIGAITTSANPF 121
Query 87 FSSSQLNYCLEISQADLVISND-------NLNLDHLDLYFKDA------CFW-------- 125
F+ ++++ + S A L+++ NL D + + D+ C
Sbjct 122 FTPAEISKQAKASAAKLIVTQSRYVDKIKNLQNDGVLIVTTDSDAIPENCLRFSELTQSE 181
Query 126 --RLKSAKAVEFPQSTQKLTFTSGTTGHPKAVCLGSEQILTVAKSLSEAIDETKPQKH-- 181
R+ S P+ L F+SGTTG PK V L + ++T S+++ +D P +
Sbjct 182 EPRVDSIPEKISPEDVVALPFSSGTTGLPKGVMLTHKGLVT---SVAQQVDGENPNLYFN 238
Query 182 -----LALMPL-AVLLENIGCYAMLYRGAQIELVSASDLGLRGASGVDVHQFSHYLNQSK 235
L ++P+ + N L GA I ++ ++ L + + K
Sbjct 239 RDDVILCVLPMFHIYALNSIMLCSLRVGATILIMPKFEITL----------LLEQIQRCK 288
Query 236 PHSLILVPQFLSVLVEAVSSKLLRAEDYRFIAVGGGHVNPDL--LKRAQTLNLPVYEGYG 293
++VP + + ++ ++ R + G + +L A+ N + +GYG
Sbjct 289 VTVAMVVPPIVLAIAKSPETEKYDLSSVRMVKSGAAPLGKELEDAISAKFPNAKLGQGYG 348
Query 294 LSECASVVALN-----TPAQQRAGSVGKPLAHVEVSIAN-----------DGEILVANNQ 337
++E V+A++ P ++G+ G + + E+ I + GEI + NQ
Sbjct 349 MTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKILDPDTGDSLPRNKPGEICIRGNQ 408
Query 338 CL-GYLGSNHAPVK------YWPTGDLGMLDEDGYLYVHGRKKHQFITSFGRNVNPEWVE 390
+ GYL A + TGD+G +D+D L++ R K + I G V P +E
Sbjct 409 IMKGYLNDPLATASTIDKDGWLHTGDVGFIDDDDELFIVDRLK-ELIKYKGFQVAPAELE 467
Query 391 ALLSQTGVVGQAFVYGEALPENYALLWPV-------HSAISNDQIEQVVEQANIKLPDYA 443
+LL + V A+ E A PV S IS D+I+Q V +
Sbjct 468 SLLIGHPEINDVAVV--AMKEEDAGEVPVAFVVRSKDSNISEDEIKQFVSK--------- 516
Query 444 RVKHWVRLTEPFSTTNQLATANGRLRRDEIVSRYHN 479
+V + R+ + F T + +G++ R ++ +R N
Sbjct 517 QVVFYKRINKVFFTDSIPKAPSGKILRKDLRARLAN 552
>Q55DR6 Fatty acyl-CoA synthetase A [Dictyostelium discoideum]
Length=667
Score = 77.0 bits (188), Expect = 6e-18
Identities = 107/436 (25%), Positives = 174/436 (40%), Gaps = 96/436 (22%)
Query 133 VEFPQSTQKLTFTSGTTGHPKAVCLGSEQILTVAKSLSEAIDETKPQK-HLALMPLAVLL 191
V P+ L +TSG+TG+PK V L +++ + + P+ H++ +PLA
Sbjct 225 VPSPEDLCTLLYTSGSTGNPKGVMLTHTNMVSEVAGANFSPAGVIPEDVHMSYLPLAHSF 284
Query 192 ENIGCYAMLYRGAQIELVSA------SDLG------LRGASGV--DVHQ----------- 226
E M Y G QI S +D+ L GA V +H
Sbjct 285 ERAVVSLMCYVGGQIGFFSGLIPELFNDIQVLRPTFLCGAPRVWQRLHDKLWFTVNNDSW 344
Query 227 -----FSHYLNQSKPHSLIL---VPQFLSVLVEAVSSKLLRAEDYRFIAVGGGHVNPDLL 278
F+ LN SK +L L P + ++ +L +FI G ++P L
Sbjct 345 LKKFLFNWGLN-SKQSALRLGSTTPIWDKLVFSKTKDRL--GGRVKFILSGSAPLDPKLA 401
Query 279 KRAQT-LNLPVYEGYGLSECASVVALNTPAQQRAGSVGKPLAHVEVSIAN---------- 327
+ + PV GYGLSE ++ P G VG PL+ E+ + +
Sbjct 402 EFLRACFCCPVVSGYGLSENVGGASVAYPEDNNVGHVGPPLSACEMKLIDVPEMNYFSTD 461
Query 328 ----DGEILVAN-NQCLGYLGSNHAPVK------YWPTGDLGMLDEDGYLYVHGRKKHQF 376
GE+ + N GY + ++ TGD+G +E+G L + RKK+ F
Sbjct 462 KPCPRGEVCIRGFNVFKGYFKDPEKTKEDLKEDGWFHTGDIGRWNENGTLSIIDRKKNIF 521
Query 377 ITSFGRNVNPEWVEALLSQTGVVGQAFVYGEAL-----------------------PE-- 411
S G V E++E++ ++ Q FVYG++L PE
Sbjct 522 KLSQGEYVAAEYLESVFVRSPFASQVFVYGDSLNSFLVGVVVPDFEVVQKLFASKYPELD 581
Query 412 --NYALLWPVHSAISNDQIEQVVEQ-----ANIKLPDYARVKHWVRLTEPFSTTNQLATA 464
N+A L A S + ++++ A KL + ++KH EPF+ N L T
Sbjct 582 VSNHATL-----AKSKELYKEILSSFDACAAEAKLHGFEKLKHIYVEHEPFTEENNLLTP 636
Query 465 NGRLRRDEIVSRYHNV 480
+ + +R ++ RY +
Sbjct 637 SFKPKRPQLKERYQTI 652
>Q9ULC5 Long-chain-fatty-acid--CoA ligase 5 [Homo sapiens]
Length=683
Score = 77.0 bits (188), Expect = 6e-18
Identities = 100/430 (23%), Positives = 169/430 (39%), Gaps = 100/430 (23%)
Query 136 PQSTQKLTFTSGTTGHPKAVCLGSEQILTVA----KSLSEAIDETKPQKHLALMPLAVLL 191
P+ + FTSGTTG PK + + I++ A K + A + T ++ +PLA +
Sbjct 252 PEDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAHMF 311
Query 192 ENIGCYAMLYRGAQIELVSASDLGLRGASGVDVHQFSHYLNQSKPHSLILVPQFLSVLVE 251
E I + GA++ D+ + + KP VP+ L+ + +
Sbjct 312 ERIVQAVVYSCGARVGFFQG-----------DIRLLADDMKTLKPTLFPAVPRLLNRIYD 360
Query 252 -----------------AVSSK-------LLRAEDY-----------------RFIAVGG 270
AVSSK ++R + + R I G
Sbjct 361 KVQNEAKTPLKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGA 420
Query 271 GHVNPDLLKRAQT-LNLPVYEGYGLSECASVVALNTPAQQRAGSVGKPLA--HVEV---- 323
++ ++ + + VYE YG +EC P +G VG PLA +V++
Sbjct 421 APMSTSVMTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVA 480
Query 324 -----SIANDGEILV-ANNQCLGYLGSNHAPVK------YWPTGDLGMLDEDGYLYVHGR 371
++ N+GE+ + N GYL + + TGD+G +G L + R
Sbjct 481 DMNYFTVNNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKIIDR 540
Query 372 KKHQFITSFGRNVNPEWVEALLSQTGVVGQAFVYGEALPE--------------NYALLW 417
KK+ F + G + PE +E + +++ V Q FV+GE+L ++A
Sbjct 541 KKNIFKLAQGEYIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKL 600
Query 418 PVHSAISNDQIEQVVEQANIK----------LPDYARVKHWVRLTEPFSTTNQLATANGR 467
V + QVV +A ++ L + +VK EPFS N L T +
Sbjct 601 GVKGSFEELCQNQVVREAILEDLQKIGKESGLKTFEQVKAIFLHPEPFSIENGLLTPTLK 660
Query 468 LRRDEIVSRY 477
+R E+ S+Y
Sbjct 661 AKRGEL-SKY 669
Score = 20.0 bits (40), Expect = 3.8
Identities = 25/110 (23%), Positives = 44/110 (40%), Gaps = 22/110 (20%)
Query 335 NNQCLGYLGSN--HAPVKYWPTGDLGMLDEDGYLYVHGRKK---HQFITSFGRNVNPEWV 389
N CLGY N + + Y D + G +H K QF+ F +N PEW+
Sbjct 90 NGPCLGYRKPNQPYRWLSYKQVSD--RAEYLGSCLLHKGYKSSPDQFVGIFAQN-RPEWI 146
Query 390 EALLSQTGVVGQAFVYGEALPENYALLWPVHSAISNDQIEQVVEQANIKL 439
+ L+ + Y + P++ + + I +V +A+I +
Sbjct 147 ISELA-------CYTYS-------MVAVPLYDTLGPEAIVHIVNKADIAM 182
>Q6ETN3 4-coumarate--CoA ligase 3 [Oryza sativa subsp. japonica]
Length=554
Score = 76.3 bits (186), Expect = 9e-18
Identities = 94/383 (25%), Positives = 163/383 (43%), Gaps = 57/383 (15%)
Query 130 AKAVEFPQSTQKLTFTSGTTGHPKAVCLGSEQILTVAKSLSEAIDETKPQKH-------L 182
A A P L ++SGTTG PK V L ++T S+++ +D P + L
Sbjct 173 ADADVHPDDVVALPYSSGTTGLPKGVMLTHRSLIT---SVAQQVDGENPNLYFSKDDVIL 229
Query 183 ALMPLAVLLE-NIGCYAMLYRGAQIELVSASDLGLRGASGVDVHQFSHYLNQSKPHSLIL 241
L+PL + N A L G+ I ++ DLG ++ + H++ +
Sbjct 230 CLLPLFHIYSLNSVLLAGLRAGSTIVIMRKFDLGA-------------LVDLVRKHNITI 276
Query 242 VPQFLSVLVEAVSSKLLRAED---YRFIAVGGGHVNPDLLK--RAQTLNLPVYEGYGLSE 296
P ++VE S + AED R + G + DL A+ N + +GYG++E
Sbjct 277 APFVPPIVVEIAKSPRVTAEDLASIRMVMSGAAPMGKDLQDAFMAKIPNAVLGQGYGMTE 336
Query 297 CASVVAL-----NTPAQQRAGSVGKPLAHVEVSIAN-----------DGEILVANNQCL- 339
V+A+ P + ++GS G + + E+ I + GEI + Q +
Sbjct 337 AGPVLAMCLAFAKEPFKVKSGSCGTVVRNAELKIVDPDTGTSLGRNQSGEICIRGEQIMK 396
Query 340 GYLGSNHAPVK------YWPTGDLGMLDEDGYLYVHGRKKHQFITSFGRNVNPEWVEALL 393
GYL A + TGD+G +D+D +++ R K + I G V P +EALL
Sbjct 397 GYLNDPEATKNTIDEDGWLHTGDIGFVDDDDEIFIVDRLK-EIIKYKGFQVPPAELEALL 455
Query 394 SQTGVVGQAFVYGEALPENYALLWPVHSAISNDQIEQVVEQANIKLPDYARVKHWVRLTE 453
+ A V ++ ++ A PV + + E + + IK V + R+ +
Sbjct 456 ITHPEIKDAAVV--SMKDDLAGEVPVAFIVRTEGSE--ITEDEIKKFVAKEVVFYKRINK 511
Query 454 PFSTTNQLATANGRLRRDEIVSR 476
F T + +G++ R ++ +R
Sbjct 512 VFFTDSIPKNPSGKILRKDLRAR 534
>M4IQS1 Probable CoA ligase CCL10 [Humulus lupulus]
Length=543
Score = 75.5 bits (184), Expect = 1e-17
Identities = 120/539 (22%), Positives = 231/539 (43%), Gaps = 91/539 (17%)
Query 6 SDFKSKLENYQFQQ----PYNIAL--SDKYQTINYADLLSEVNKRQEILKQLDVK---VV 56
+D K L ++ F+ P AL +D QT+ + L ++V+K L QL++K VV
Sbjct 23 TDPKLSLTSFLFRSSASYPNRTALIDADSGQTLTFLKLKTQVSKLAHSLVQLNIKKNDVV 82
Query 57 ALYLENSVDLMLWDLTLLFSEIPTIILPPFFSSSQL-------NYCLEISQADLVISNDN 109
++ NS+ + ++ T P ++ ++L N L I+ +L
Sbjct 83 LIFAPNSIHFPVCFFSIAALGAITTTCNPSYTFTELSNQAKDCNPTLVITVPELWEKARK 142
Query 110 LNLDHLDL-------YFKDACFWRL-----KSAKAVEFPQSTQK------LTFTSGTTGH 151
LNL + L + FW KS + E P S + L ++SGTTG
Sbjct 143 LNLPAIILPSPSNSKLSSKSEFWFFSDLTRKSDRFSELPISDVRQSDVAALLYSSGTTGK 202
Query 152 PKAVCLGSEQILTVAKSLSEAIDETKPQKHLAL--MPLAVLLE-NIGCYAMLYRGAQIEL 208
K V L + +T + ++ D +++ + +P+ + ++ Y+ L RG +
Sbjct 203 SKGVVLSHKNFITTSLMVTSDQDRYGDPQNICMCFLPMFHIFGLSVIAYSQLRRGNGV-- 260
Query 209 VSASDLGLRGA-SGVDVHQFSHYLNQSKPHSLILVPQFLSVLVEAVSSKLLRAEDYRFIA 267
VS L GA V++++ +H ++ P +++ E+V + + I
Sbjct 261 VSMGKFELEGALRAVEMYRVTHLF--------VVPPVMIALAKESVVVRRYDLSSVKEIL 312
Query 268 VGGGHVNPDLLKRAQTLNLP---VYEGYGLSECASVVALNTPAQ--QRAGSVGKPLAHVE 322
G + +++++ N+P + +GYG++E ++++ + + +GS G +E
Sbjct 313 SGAAPLGKNVMEQCAR-NVPGAAIIQGYGMTETCGIISIEDSKKGCRFSGSTGMLAPGIE 371
Query 323 VSIAN-----------DGEI-LVANNQCLGYLGSNHAPVK------YWPTGDLGMLDEDG 364
I + +GEI L N GYL + A + TGD+G DE+G
Sbjct 372 SQIMDTKRWNPLPPNQEGEIWLRGPNMMQGYLNNLEATKSTIDEQGWVKTGDIGYFDEEG 431
Query 365 YLYVHGRKKHQFITSFGRNVNPEWVEALLSQTGVVGQAFVYGEALPENYALLWPV----- 419
L+V R K + I +G V P +EALL + A V P+ A P+
Sbjct 432 QLFVVDRLK-ELIKCYGFQVAPAELEALLLSHPEILDAVVI--PFPDEKAGEVPIANVVR 488
Query 420 --HSAISNDQIEQVVEQANIKLPDYARVKHWVRLTEPFSTTNQLATANGRLRRDEIVSR 476
+S++S + +++ +E+ +V + +L ++ L + G++ R E++ +
Sbjct 489 SPNSSLSEEDVQRFIEK---------QVAPFKKLRRVTFVSSVLKSPAGKILRRELIQK 538
Lambda K H a alpha
0.320 0.135 0.399 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 3812952
Database: 459afe0c64c4247e04f3f05f02fc2102.SwissProt.fasta
Posted date: May 9, 2024 2:06 AM
Number of letters in database: 9,933
Number of sequences in database: 19
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
