BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 019f72833dddd60d302b508054c3560e.SwissProt.fasta
10 sequences; 39,991 total letters
Query= ACIAD2192
Length=382
Score E
Sequences producing significant alignments: (Bits) Value
Q54G05 Putative leucine-rich repeat-containing protein DDB_G02905... 45.8 1e-07
Q8WXH0 Nesprin-2 [Homo sapiens] 42.7 1e-06
P33420 Protein NIP100 [Saccharomyces cerevisiae (strain ATCC 2045... 40.4 5e-06
B8I5R4 Proline--tRNA ligase [Ruminiclostridium cellulolyticum (st... 40.0 6e-06
Q02455 Protein MLP1 [Saccharomyces cerevisiae (strain ATCC 204508... 39.3 1e-05
C6KTD2 Putative histone-lysine N-methyltransferase 1 [Plasmodium ... 39.3 1e-05
G4SLH0 Titin homolog [Caenorhabditis elegans] 37.0 7e-05
A9CS50 Probable phenylalanine--tRNA ligase beta subunit [Enterocy... 36.6 8e-05
Q15075 Early endosome antigen 1 [Homo sapiens] 30.0 0.010
Q8NCX0 Coiled-coil domain-containing protein 150 [Homo sapiens] 22.7 1.8
>Q54G05 Putative leucine-rich repeat-containing protein DDB_G0290503
[Dictyostelium discoideum]
Length=1492
Score = 45.8 bits (107), Expect = 1e-07
Identities = 66/314 (21%), Positives = 145/314 (46%), Gaps = 37/314 (12%)
Query 5 KFDSLVISDRDIIDLLDAQKG-----KISKEKLLDFLQERGIFCSENETRNALHERIAAL 59
K + L+ D + L++ + K+ +L D LQE+ N++ ++E + L
Sbjct 469 KENQLISKDNQLNQLIENNESSSDELKLKLNQLSDELQEKDEKLLNNQS--VINELQSNL 526
Query 60 SIDWFLIEDILSLAASKENFQKVTATNFTLPKADALETTLENLKSQLSNKDFIVDKLKNG 119
+ + I +++ S + K+ + K + L++L+S + +D +D+L++
Sbjct 527 NENQNKINELIENNQSSSDELKLKLNQLS-DKLQEKDEKLKSLESSIIERDEKIDQLQDN 585
Query 120 NYEIQYKVDKIEKNN--------ARLIQRT----SKDEKISIN---LDGDQATIVNTVGE 164
E Q K++++ +NN ++LIQ + KDEK+ N ++ Q+ + +
Sbjct 586 LNEKQDKINELVENNESSSDELQSKLIQLSDQLQEKDEKLLNNQSIINELQSNLNENQNK 645
Query 165 GTDTVVQTFFNELERNSK-----TEIKNTSINFSSIIDNTIINKYFLDLIKIDAKKYKVI 219
+ + + E NSK E+K+ + N S+ + I N+ LD ++ +
Sbjct 646 INELIENNQSSSDELNSKLIKLSDELKDKNENVRSLETSIIENQDKLD--QLIQSNQVTV 703
Query 220 DVIKLKLNKFNSNVSEELELEDVDITDELNSDPDKQKDELDKEDIKSALISGSSLLASNL 279
+ ++ KLN+ N+++ +E + DEL S +++++E+++ LI + + L
Sbjct 704 NELQSKLNEKEININQLIENNQSSL-DELQSKLNEKQNEINQ------LIENNQSSSDEL 756
Query 280 FKVLSNKGYFISSI 293
L+ K IS +
Sbjct 757 QSKLNEKHQEISEL 770
Score = 40.8 bits (94), Expect = 4e-06
Identities = 54/226 (24%), Positives = 112/226 (50%), Gaps = 42/226 (19%)
Query 92 ADALETTLENLKSQLSNKD-------FIVDKLKNGNYEIQYKVDKIEKNN--------AR 136
+D L++ L L QL KD I+++L++ E Q K++++ +NN ++
Sbjct 604 SDELQSKLIQLSDQLQEKDEKLLNNQSIINELQSNLNENQNKINELIENNQSSSDELNSK 663
Query 137 LIQRTSKDEKISINLDGDQATIVNTVGEGTDTVVQTFFNELERNS-KTEIKNTSINFSSI 195
LI+ + + + + N+ + +I+ + D ++Q+ N++ N ++++ IN + +
Sbjct 664 LIKLSDELKDKNENVRSLETSIIENQDK-LDQLIQS--NQVTVNELQSKLNEKEININQL 720
Query 196 IDNTIINKYFLDLI--KIDAKKYKV----------IDVIKLKLNKFNSNVSE------EL 237
I+N N+ LD + K++ K+ ++ D ++ KLN+ + +SE EL
Sbjct 721 IEN---NQSSLDELQSKLNEKQNEINQLIENNQSSSDELQSKLNEKHQEISELQSKLNEL 777
Query 238 ELEDVDITDELNSDPDKQKDELDKEDIKSALISGSSLLASNLFKVL 283
+ +DEL S + DEL ++D K L S S++ N K++
Sbjct 778 IENNESSSDELQSKLIQLSDELKEKDEK--LKSLDSIIIENQEKLV 821
Score = 35.0 bits (79), Expect = 3e-04
Identities = 48/199 (24%), Positives = 94/199 (47%), Gaps = 37/199 (19%)
Query 96 ETTLENLKSQLSNKDFIVDKLKNGNYEIQYKVDKIE-KNNARLIQRTSKDEKISINLDGD 154
+++L+ L+S L+ K +++L N Q +D+++ K N +L + KD KI+ + +
Sbjct 977 QSSLDELQSNLNEKQNEINQLIENN---QSSLDELQSKLNEKLNEINEKDNKINELIQTN 1033
Query 155 QATIVNTVGEGTDTVVQTFFNELE-RNSKTEIKNTSI---NFSSIIDNTIINKYFLDLIK 210
++ + + + + ELE +N+K N+ I N +N+ L LI+
Sbjct 1034 ES-----LSKDQQSKFENLEQELEEKNNKILDLNSQIIDVNHQFSEKENELNQLQLKLIE 1088
Query 211 ----IDAKKYKVIDVI--------KLKLNKFNSN-------VSEELELEDVDITDELNSD 251
I+ + K+ID+ ++ +N N N + EEL+ + D+ +ELN +
Sbjct 1089 KDQEIENQNNKIIDINNQLNEKEKEININNDNDNNNEENIQLIEELKEKLQDLENELNLE 1148
Query 252 PDKQKDELD-----KEDIK 265
D ++ D KE+IK
Sbjct 1149 KDTVNEKNDDINELKEEIK 1167
Score = 33.1 bits (74), Expect = 0.001
Identities = 45/173 (26%), Positives = 84/173 (49%), Gaps = 20/173 (12%)
Query 92 ADALETTLENLKSQLSNKDFIVDKLKNGNYEIQYKVDKIEKNNARLIQRTSKDEKISINL 151
+D L++ L L +L KD + L + E Q K+ ++ K+N + S DE + L
Sbjct 785 SDELQSKLIQLSDELKEKDEKLKSLDSIIIENQEKLVQLTKSN-----QDSLDE-LQSKL 838
Query 152 DGDQATIVNTVGEGTDTVVQTFFNELERNSKTEIKNTSINFSSIIDNTIINKYFLDLIKI 211
+ Q I + Q+ NEL+ SK K IN +I+N N+ D ++
Sbjct 839 NEKQNEINELIENN-----QSSSNELQ--SKLNEKQNEINL--LIEN---NQSSSDELQS 886
Query 212 DA-KKYKVIDVIKLKLNKFNSNVSEELELEDVDITDELNSDPDKQKDELDKED 263
+K++ I+ ++ KLN+ + ++E +E + +DEL S + D+L +++
Sbjct 887 KLNEKHQEINELQSKLNEKQNKINELVE-NNESSSDELQSKLIQLSDQLQEKE 938
Score = 30.8 bits (68), Expect = 0.006
Identities = 36/185 (19%), Positives = 90/185 (49%), Gaps = 32/185 (17%)
Query 96 ETTLENLKSQLSNKDFIVDKLKNGNYEIQYKVDKIEKNNARLIQR-----TSKDEKISIN 150
E L++ +S + +D +++L++ E Q ++D+I +NN + K +I+
Sbjct 938 ENQLKSFESSIIERDEKLNQLQSKLNEKQNEIDQITENNQSSLDELQSNLNEKQNEINQL 997
Query 151 LDGDQATI----------VNTVGEGTDTVVQTFFNELERNSKTEIKNTSINFSSI----- 195
++ +Q+++ +N + E + + NEL + +++ K+ F ++
Sbjct 998 IENNQSSLDELQSKLNEKLNEINEKDNKI-----NELIQTNESLSKDQQSKFENLEQELE 1052
Query 196 -IDNTI--INKYFLDLIKIDAKKYKVIDVIKLKLNKFNSNVSEELELEDVDITDELNSDP 252
+N I +N +D+ ++K ++ ++LKL + + + E + +DI ++LN
Sbjct 1053 EKNNKILDLNSQIIDVNHQFSEKENELNQLQLKLIEKDQEI-ENQNNKIIDINNQLN--- 1108
Query 253 DKQKD 257
+K+K+
Sbjct 1109 EKEKE 1113
Score = 29.3 bits (64), Expect = 0.017
Identities = 37/164 (23%), Positives = 81/164 (49%), Gaps = 20/164 (12%)
Query 96 ETTLENLKSQLSNKDFIVDKLKNGNYEIQYKVDKIEKNNARLIQRTSKDEKI-SINLDGD 154
E +++L QLS+KD + +K+ +++ VD ++ I++T KD +I +
Sbjct 177 EQEIKSLTLQLSSKD---ESMKSLEKQVEKLVDIEHRSE---IEQTKKDNEILKLTEKIK 230
Query 155 QATIVNTVGEGTDTVV-QTFFNELER--NSKTEIKNTSINFSSIID------NTIINKYF 205
+ ++ + D+ V Q + ++R S EIK+ + + S+ID IN+Y
Sbjct 231 EIQLIENLNSTNDSKVNQLLEDNIKRLQESLNEIKDENNDLQSLIDTQKQQFEKRINQYQ 290
Query 206 LDLIKIDAKKYKVIDVIKLKLNKFNSNVSEELELEDVDITDELN 249
L+ I K+ ++ ++ + L++ S + L+ +D+ ++ N
Sbjct 291 LE---IQDKENELNEMNQQSLSQVKS-FQQSLQQSQLDLENDKN 330
Score = 28.5 bits (62), Expect = 0.029
Identities = 52/245 (21%), Positives = 98/245 (40%), Gaps = 40/245 (16%)
Query 68 DILSLAASKENFQKVTATNFTLPKA--DALETTLENLKSQLSNKDFIVDKLKNGNYEIQY 125
+IL L + Q + N T LE ++ L+ L+ ++K+ N ++Q
Sbjct 221 EILKLTEKIKEIQLIENLNSTNDSKVNQLLEDNIKRLQESLN-------EIKDENNDLQS 273
Query 126 KVDKIEKNNARLIQRTSKDEKISINLDGDQATIVNTVGEGTDTVVQTFFNELERN----- 180
+D ++ + I + + + D+ +N + + + + V++F L+++
Sbjct 274 LIDTQKQQFEKRINQYQLEIQ-------DKENELNEMNQQSLSQVKSFQQSLQQSQLDLE 326
Query 181 -------SKTEIKNTSI-NFSSIIDNTIINKYFLDLIKIDAKKYKVIDVIK-----LKLN 227
+K ++ N I + SI+D+ + D + ID K L+LN
Sbjct 327 NDKNQFSTKLQLVNNEIQSLKSIVDDKLKEIQLKDNQLTQLNQQHEIDNNKNNQMILELN 386
Query 228 KFNSNVSEELELEDVDITDELNSDPDKQKD------ELDKEDIKSALISGSSLLASNLFK 281
S +S +L +D I + DKQK+ D+ +K IS L N
Sbjct 387 DNISKISNQLNEKDNKIQELSKQSIDKQKEIENSTSSSDQLQLKLNDISNELLEKLNDIN 446
Query 282 VLSNK 286
LSNK
Sbjct 447 QLSNK 451
Score = 28.5 bits (62), Expect = 0.029
Identities = 42/199 (21%), Positives = 94/199 (47%), Gaps = 19/199 (10%)
Query 96 ETTLENLKSQLSNKDFIVDKLKNGNY----EIQYKVDKIEKNNARLIQRT-SKDEKISIN 150
+ +L+ L+S+L+ K +++L N E+Q K+++ + LI+ S +++
Sbjct 828 QDSLDELQSKLNEKQNEINELIENNQSSSNELQSKLNEKQNEINLLIENNQSSSDELQSK 887
Query 151 LDGDQATIVNTVGEGTDTVVQTFFNELERN---SKTEIKNTSINFSSIID--NTIINKYF 205
L+ I + + Q NEL N S E+++ I S + + +
Sbjct 888 LNEKHQEINELQSKLNEK--QNKINELVENNESSSDELQSKLIQLSDQLQEKENQLKSFE 945
Query 206 LDLIKIDAKKYKVIDVIKLKLNKFNSNVSEELELEDVDITDELNSDPDKQKDELDK--ED 263
+I+ D K ++ ++ KLN+ + + + E + DEL S+ +++++E+++ E+
Sbjct 946 SSIIERDEK----LNQLQSKLNEKQNEIDQITENNQSSL-DELQSNLNEKQNEINQLIEN 1000
Query 264 IKSALISGSSLLASNLFKV 282
+S+L S L L ++
Sbjct 1001 NQSSLDELQSKLNEKLNEI 1019
>Q8WXH0 Nesprin-2 [Homo sapiens]
Length=6885
Score = 42.7 bits (99), Expect = 1e-06
Identities = 63/271 (23%), Positives = 120/271 (44%), Gaps = 27/271 (10%)
Query 26 KISKEKL----LDFLQERGIFCSENETRNALHERIAA--LSIDWFLIEDILSLAASKENF 79
KI KEKL L + + ++ E +++ A L I + + + SL ++E F
Sbjct 4752 KIGKEKLAHGHLKQTKSKVALQAQIENHKVFFQKLVADMLLIQAYSAKILPSLLQNRETF 4811
Query 80 --QKVTATNFTLPKADALETTLENLKSQLSNKDFIVDKLKNGNYEIQYK----VDKIEKN 133
++VT K+ L++L + D L+ + EI V +E+
Sbjct 4812 WAEQVTEVKILEEKSRQCGMKLQSLLQKWEEFDENYASLEK-DLEILISTLPSVSLVEET 4870
Query 134 NARLIQRTSKDEKISINLDGDQATIVNTVGEGTDTVVQTFFNELERNSKTEIKNTSINFS 193
RL++R S ++I N+ G A + T+ EG V ELE +++ ++ +
Sbjct 4871 EERLVERISFYQQIKRNIGGKHARLYQTLNEGKQLVASVSCPELE-GQIAKLEEQWLSLN 4929
Query 194 SIIDNTI-----INKYFLDLIKIDAKKYKVIDVIKLKLNKFNS---NVSEELELEDVDIT 245
ID+ + + K+ L + + K ++ + LN + NVS++L+ I
Sbjct 4930 KKIDHELHRLQALLKHLLSYNRDSDQLTKWLESSQHTLNYWKEQSLNVSQDLD----TIR 4985
Query 246 DELNSDPDKQKDELDKEDIKSALIS-GSSLL 275
+N+ + K+ +K +K+A+IS G+ LL
Sbjct 4986 SNINNFFEFSKEVDEKSSLKTAVISIGNQLL 5016
Score = 22.3 bits (46), Expect = 2.4
Identities = 26/93 (28%), Positives = 40/93 (43%), Gaps = 20/93 (22%)
Query 69 ILSLAASKENFQKVTATNFTLPKADA-----LETTLENLKSQLSNKDFIVDKLKNGN--- 120
+L LA++K QK T+ PKAD L L+ +L + VD L+ +
Sbjct 6674 LLWLASAKNRRQKAHVTD---PKADPRALLECRRELMQLEKELVERQPQVDMLQEISNSL 6730
Query 121 ---------YEIQYKVDKIEKNNARLIQRTSKD 144
E + KV IEK +L ++ S+D
Sbjct 6731 LIKGHGEDCIEAEEKVHVIEKKLKQLREQVSQD 6763
Score = 20.4 bits (41), Expect = 9.5
Identities = 9/19 (47%), Positives = 13/19 (68%), Gaps = 0/19 (0%)
Query 89 LPKADALETTLENLKSQLS 107
L KADA LEN +S+++
Sbjct 4672 LQKADAYTVELENAESRVA 4690
>P33420 Protein NIP100 [Saccharomyces cerevisiae (strain ATCC
204508 / S288c)]
Length=868
Score = 40.4 bits (93), Expect = 5e-06
Identities = 53/229 (23%), Positives = 95/229 (41%), Gaps = 34/229 (15%)
Query 56 IAALSIDWFLIEDILSLAASKENFQKVTATNFTLPKADALETTLENLK------SQLSNK 109
I SI L D L L +++++++++ +E+ LEN+ SQ ++
Sbjct 574 ITLSSILTILFSDALFL---RQDYKRISSLKKLEVFFQGIESLLENITIFPEQPSQQTSD 630
Query 110 DFIVDKLKNGNYEIQYKVDKIEKNNARLIQRTSKDEKISINLDGDQATIVN------TVG 163
+K GN+ D++ + N RL + + E + L+ I+ T+
Sbjct 631 SESQCNIKEGNFSNSLLSDRLNEENIRLKEVLVQKENMLTELETKIKIIIGRDLERKTLE 690
Query 164 EGTDTVVQTFFNELERN-SKTEI---------------KNTSINFSSIIDNTIINKYFLD 207
E T+ N+ E N KTEI KN + I DN +NK +LD
Sbjct 691 ENIKTLKVELNNKNEENCGKTEILNKLKEENFNLVNRLKNMELKLYQIKDNNTLNKIYLD 750
Query 208 LIKIDAKKYKVIDVIKLKLNKFNSNVSEELELE-DVDITDELNSDPDKQ 255
K+D + V ++++L+ + E+ + D DEL + +KQ
Sbjct 751 REKVD-RVNLVSEIMELR-ETIRRQIKEQKRVSIDFSWLDELPAVENKQ 797
Score = 36.6 bits (83), Expect = 8e-05
Identities = 36/191 (19%), Positives = 87/191 (46%), Gaps = 19/191 (10%)
Query 79 FQKVTATNFTLPKADALETTLENLKSQLSNKDFIVDKLKNGNYEIQYKVDKIEKNNARLI 138
F K +L +A + T++NL+ + + ++K+K N+E++ V+K+ N L+
Sbjct 90 FYKPDDDEHSLLNGNAAQETIKNLQVKCESLASKLNKIKIENHELKTSVEKLSTNETVLL 149
Query 139 QRTSKDEKISINL---DGDQATIVNTVGEGTDTVVQTFFNELERNSKTE--------IKN 187
+ S+ +K+ L +G+ T ++ D +L++ + E +
Sbjct 150 SKISRLDKLVKELKVENGNMKTHLDNFNHLLDASDSVMAPDLDKGTLLERSHLLQGLLDQ 209
Query 188 TSINFSSI--IDNTIINKYFLDLIKIDAKKYKVIDVIKLKLNKFNSNVSE-----ELELE 240
T +++ + ++ + L++ +A K I + L+L + N+ + + E + +
Sbjct 210 TKLSYDKAMKVQEDLLEEN-TQLLEENAVLSKKISDLGLQLQQTNNTIGDLALQIEAQSK 268
Query 241 DVDITDELNSD 251
+I D+L +D
Sbjct 269 SSNIVDKLTND 279
Score = 21.6 bits (44), Expect = 4.0
Identities = 12/46 (26%), Positives = 18/46 (39%), Gaps = 0/46 (0%)
Query 107 SNKDFIVDKLKNGNYEIQYKVDKIEKNNARLIQRTSKDEKISINLD 152
S IVDKL N N + + + L + DE + I +
Sbjct 267 SKSSNIVDKLTNDNILLTSNIKALNNELEELQAKEKLDENLRITYE 312
Score = 20.8 bits (42), Expect = 6.8
Identities = 56/273 (21%), Positives = 107/273 (39%), Gaps = 41/273 (15%)
Query 40 GIFCSENETRNALHERIAALSIDWFLIEDILSLAASKENFQKVTATNFTLPKADALETTL 99
G + EN A E I A + F ++ +E +Q F + L
Sbjct 337 GTYIEENSRLKATLESIEAKTSHKFQSLELKVNTLQEELYQNKLLKKFYQIYEPFAQPHL 396
Query 100 ENLKSQLSNKDFIVDKLKNGNYEIQYKVDKIEKNNARLIQRTSKDEKISINLDGDQATIV 159
L SQL ++ + +++ N+ K+E +I + ++++ TI
Sbjct 397 AALSSQLQ---YLAEVIESENF------GKLENIEIHIILKVLSSISYALHI----YTIK 443
Query 160 NTVGEGTDTVVQTF-------------FNELERNSKTEIKNTSINFSSIIDNTIINKYFL 206
NT + +T +Q F F + + +SK E + F + DN ++K
Sbjct 444 NTP-DHLETTLQCFKVNIAPISMWLSEFLQRKFSSKQETAFSICQF--LEDNKFLDKDVT 500
Query 207 DLIKIDAKKYKVIDVIKLKLNKF---NSNVSEELELEDVDITDE----LNSDPDKQ--KD 257
++KI + +++ KL F NSN ++ L + E L + DK K+
Sbjct 501 LILKI---LHPILETTVPKLLAFLRTNSNFNDNDTLCLIGSLYERSLSLIARIDKLIGKE 557
Query 258 ELDKEDIKSALISGSSLLASNLFKVLSNKGYFI 290
E+ K+D + L + S++ +L + F+
Sbjct 558 EISKQDNRLFLYPSCDITLSSILTILFSDALFL 590
>B8I5R4 Proline--tRNA ligase [Ruminiclostridium cellulolyticum
(strain ATCC 35319 / DSM 5812 / JCM 6584 / H10)]
Length=478
Score = 40.0 bits (92), Expect = 6e-06
Identities = 29/85 (34%), Positives = 49/85 (58%), Gaps = 3/85 (4%)
Query 115 KLKNGNYEIQYKVDKIEKNNARLIQRTSKDEKISINLDGDQATIVNTVGEGTDTVVQTFF 174
++K I+ IEKN A L++R ++ EKI ++LD + T+VNT+ + ++++
Sbjct 340 EMKGVPLRIEIGPKDIEKNQAVLVRRDNR-EKIFVSLDNLEETVVNTLADVQKSLLEK-A 397
Query 175 NELERNSKTEIKNTSINFSSIIDNT 199
EL R+ KT I T F II++T
Sbjct 398 REL-RDKKTYIAATLEEFDQIINST 421
>Q02455 Protein MLP1 [Saccharomyces cerevisiae (strain ATCC 204508
/ S288c)]
Length=1875
Score = 39.3 bits (90), Expect = 1e-05
Identities = 67/305 (22%), Positives = 133/305 (44%), Gaps = 42/305 (14%)
Query 9 LVISDRDIIDLLDAQKGKISKEKLLDFLQERGIFCSENETRNALHERIAALSIDWFLIED 68
L I + ++++L + QK ++ EK L QE E ++ + ++ L + ED
Sbjct 742 LSIVETELLNLKEEQKLRVHLEKNLK--QELNKLSPEKDSLRIMVTQLQTLQKER---ED 796
Query 69 ILSLAASKENFQKVTATNFTLPKADALETTLENLKSQLSNKDFIVDKLK---NGNYE-IQ 124
+L ++++ QK K D LE L LK + S KD + +L+ N N E Q
Sbjct 797 LLE--ETRKSCQK---------KIDELEDALSELKKETSQKDHHIKQLEEDNNSNIEWYQ 845
Query 125 YKVDKIEKNNARLIQRTSKDEKISINLDGDQATIVNTVGEGTDTVVQTFFNELER----- 179
K++ ++K+ +I + L ++ + E D + +N ++
Sbjct 846 NKIEALKKDYESVITSVDSKQTDIEKLQYKVKSLEKEIEE--DKIRLHTYNVMDETINDD 903
Query 180 NSKTEIKNTSINFSSIIDNTIINKYFLDLIKIDAKKY-----KVIDVIKLKLNKFNSNVS 234
+ + E++ + IN + K + DL + ++ K+ + K N+ +
Sbjct 904 SLRKELEKSKINLTDAYSQI---KEYKDLYETTSQSLQQTNSKLDESFKDFTNQIKNLTD 960
Query 235 EELELED-VDITDE----LNSDPDKQKDELDKEDIKSALISGSSLLASNLFKVLSNKGYF 289
E+ LED + + E LN++ D QK ++KE K+ S+L +N +V + K +
Sbjct 961 EKTSLEDKISLLKEQMFNLNNELDLQKKGMEKE--KADFKKRISILQNNNKEVEAVKSEY 1018
Query 290 ISSIA 294
S ++
Sbjct 1019 ESKLS 1023
Score = 31.6 bits (70), Expect = 0.003
Identities = 55/271 (20%), Positives = 112/271 (41%), Gaps = 32/271 (12%)
Query 26 KISKEKLLDFLQERGIFCSENETRNALHERI-AALSIDWFLIEDILSLAAS----KENFQ 80
K +K K L+ ++ + C EN+ + +R+ I + LI + +S + KE Q
Sbjct 449 KNAKVKELNAKNQKLVEC-ENDLQTLTKQRLDLCRQIQYLLITNSVSNDSKGPLRKEEIQ 507
Query 81 KVT----ATNFTLPKADALETTLENLKSQLSNKDFIVDKLKNGNY--EIQYKVDKIEKNN 134
+ + T+ ++D+ + E L + K+ I + KN ++ DK+E
Sbjct 508 FIQNIMQEDDSTITESDSQKVVTERL---VEFKNIIQLQEKNAELLKVVRNLADKLESKE 564
Query 135 ARLIQRTSKDEKISINLDGDQATIVNTVGEGTDTVVQTFFNELERNSKTEIKNTSINFSS 194
+ Q K E ++N + + + ++ ++ ELE KT + N ++S+
Sbjct 565 KKSKQSLQKIESETVNEAKEAIITLKSEKMDLESRIEELQKELEE-LKTSVPNEDASYSN 623
Query 195 IIDNTIINKYFLDLIKIDAKKYKVIDVIKLKLNKFNSNVSEELELEDVDITDELNSDPDK 254
+ + K D + + ++ ++++ +E + L + +I D +S D
Sbjct 624 VTIKQLTET------KRDLESQ--VQDLQTRISQITRESTENMSLLNKEIQDLYDSKSDI 675
Query 255 QKDELDKEDIKSALISGSSLLASNLFKVLSN 285
IK S +LA FK+LSN
Sbjct 676 S--------IKLGKEKSSRILAEERFKLLSN 698
Score = 25.8 bits (55), Expect = 0.20
Identities = 74/364 (20%), Positives = 138/364 (38%), Gaps = 65/364 (18%)
Query 80 QKVTATNFTLPKADALETTLENLKSQLSNKDFIVDKLKNG-----------NYEIQYKVD 128
+K+ N L LEN ++ +DKLK Y +Q K
Sbjct 1211 EKLNQLNLLRESNITLRNELENNNNKKKELQSELDKLKQNVAPIESELTALKYSMQEKEQ 1270
Query 129 --KIEKNNARLIQRTSKD-------------EKISINLDGDQATIVNTVGEGTDTVVQTF 173
K+ K ++ S+D EK+ ++ + + N +G + +
Sbjct 1271 ELKLAKEEVHRWKKRSQDILEKHEQLSSSDYEKLESEIENLKEELENKERQGAE--AEEK 1328
Query 174 FNELERNSKTEIKNTSINFSSIID---------NTIINKYFLDLIKID-------AKKYK 217
FN L R ++ +K + ++ S+ + N + N +I+ A+
Sbjct 1329 FNRLRRQAQERLKTSKLSQDSLTEQVNSLRDAKNVLENSLSEANARIEELQNAKVAQGNN 1388
Query 218 VIDVIKLKLNKFNSNVSEELE--LEDVDITDE-----LNSDPDKQKDELDKE-DIKSALI 269
++ I+ KL + S EL+ LE+ + E LN + K+E++K+ I+ L
Sbjct 1389 QLEAIR-KLQEDAEKASRELQAKLEESTTSYESTINGLNEEITTLKEEIEKQRQIQQQLQ 1447
Query 270 SGSSLLASNLFKVL-SNKGYFISSIAWLVLEKTGE--KRKIEYSSGFTDPDKRDIFTFES 326
+ S+ ++L ++ S K F + EKT E ++ +E P ++ +
Sbjct 1448 ATSANEQNDLSNIVESMKKSFEEDKIKFIKEKTQEVNEKILEAQERLNQPSNINMEEIKK 1507
Query 327 KGFFE--------INSATQDYKKN-RTTWKSNQRKMIEFAFQKYAFSLFQTVIEKVDSNE 377
K E I A + KK R + K+IE ++ + V E++ S E
Sbjct 1508 KWESEHEQEVSQKIREAEEALKKRIRLPTEEKINKIIERKKEELEKEFEEKVEERIKSME 1567
Query 378 GSNE 381
S E
Sbjct 1568 QSGE 1571
Score = 24.3 bits (51), Expect = 0.60
Identities = 14/55 (25%), Positives = 32/55 (58%), Gaps = 1/55 (2%)
Query 92 ADALETTLENLKSQLSNKDFIVDKLKNGNYEIQYKVDKI-EKNNARLIQRTSKDE 145
+D+L + + +++S K +VD L++ ++ +++ I E N A++I SK +
Sbjct 282 SDSLNSEKQEFSAEMSLKQRLVDLLESQLNAVKEELNSIRELNTAKVIADDSKKQ 336
Score = 21.6 bits (44), Expect = 4.1
Identities = 51/225 (23%), Positives = 96/225 (43%), Gaps = 26/225 (12%)
Query 48 TRNALHERIAALSIDWFLIEDILSLAASK-ENFQ--KVTATNFTLPKADALETTLEN--- 101
++++L E++ +L ++E+ LS A ++ E Q KV N L L+ E
Sbjct 1346 SQDSLTEQVNSLRDAKNVLENSLSEANARIEELQNAKVAQGNNQLEAIRKLQEDAEKASR 1405
Query 102 -LKSQLSNKDFIVDKLKNG-NYEIQYKVDKIEKNNARLIQRTSKDEKISINLDGDQATIV 159
L+++L + NG N EI ++IEK R IQ+ + S N D + IV
Sbjct 1406 ELQAKLEESTTSYESTINGLNEEITTLKEEIEKQ--RQIQQQL--QATSANEQNDLSNIV 1461
Query 160 NTVGEGTDTVVQTFFNEL--ERNSKTEIKNTSINFSSIIDNTIINKYFLDLIKIDAKKYK 217
++ + + F E E N K +N S I+ I K + + +
Sbjct 1462 ESMKKSFEEDKIKFIKEKTQEVNEKILEAQERLNQPSNINMEEIKKKW---------ESE 1512
Query 218 VIDVIKLKLNKFNSNVSEELELEDVDITDELNSDPDKQKDELDKE 262
+ K+ + + + + L +++N +++K+EL+KE
Sbjct 1513 HEQEVSQKIREAEEALKKRIRLPT---EEKINKIIERKKEELEKE 1554
Score = 20.8 bits (42), Expect = 7.1
Identities = 26/110 (24%), Positives = 52/110 (47%), Gaps = 10/110 (9%)
Query 32 LLDFLQERGIFCSENETRNALHERIAALSIDWFLIEDI-LSLAASKENFQKVTATNFT-- 88
L+ +ER I +T+ + ER A + + D+ L A +K + +V N +
Sbjct 1147 LITLRRERDIL----DTKVTVAERDAKMLRQKISLMDVELQDARTKLDNSRVEKENHSSI 1202
Query 89 LPKADALETTLENLKSQLSNKDFIVDKLKNGNY---EIQYKVDKIEKNNA 135
+ + D + L L + + ++L+N N E+Q ++DK+++N A
Sbjct 1203 IQQHDDIMEKLNQLNLLRESNITLRNELENNNNKKKELQSELDKLKQNVA 1252
>C6KTD2 Putative histone-lysine N-methyltransferase 1 [Plasmodium
falciparum (isolate 3D7)]
Length=6753
Score = 39.3 bits (90), Expect = 1e-05
Identities = 43/181 (24%), Positives = 82/181 (45%), Gaps = 20/181 (11%)
Query 95 LETTLENLKS-QLSNKDFIVDKLK---------NGNYEIQYKVDKIEKNNARLIQRTSKD 144
L+TT EN+KS ++ +K+F+ K K N N +++ + + ++N + I++ D
Sbjct 4251 LKTTTENIKSNEVEDKEFVDKKKKRKLSVKVKVNVNVKVELQDTENDENKEKGIKKEKND 4310
Query 145 EKISINLDGDQATIVNTVGEGTDTVVQTFFNELERNSKTEIKNTSINFSSIIDNTIINKY 204
E+ D ++ N G V+ N+ + + E +N N ++ + IIN
Sbjct 4311 EE--KKNDAEKKKKENKKGREKSVKVRKTKNQTQVERENEKENLMENVTNDKTSDIINNK 4368
Query 205 FLDLIKIDAKKYKVIDVIKLKLNK-FNSNVSEELELEDVDITDELNSD--PDKQKDELDK 261
D+I K D+I K + N+ S+ + + DI + SD DK D ++
Sbjct 4369 TSDII-----NNKTSDIINNKTSDIINNKTSDIINNKTSDIINNKTSDIINDKTNDIINN 4423
Query 262 E 262
+
Sbjct 4424 K 4424
Score = 37.0 bits (84), Expect = 7e-05
Identities = 51/187 (27%), Positives = 79/187 (42%), Gaps = 41/187 (22%)
Query 98 TLENLKSQLSNKDFIVDKLKNGNYEIQYKVDKI--EKNNARLIQRTS-KDEKISINLDGD 154
T EN +L + D+L N E YK D + EKN L+ + S E+ + N +
Sbjct 2643 TKENDIIKLDEDNKQKDELNEANKECFYKQDDVHVEKNCDELLYKNSFNSEECNKN---E 2699
Query 155 QATIVNTVGEGTDTVVQTFFNELERNSKTEIKNTSINFSSIIDNTII----NKYFLDLIK 210
+ N V E D V ++N N + + ++ IDNT++ NK DL
Sbjct 2700 KKKNDNNVDENDDNV--------DKNDDNNNNNNNGDDNNNIDNTLVDGDMNKLENDLNN 2751
Query 211 I-------------DAKKYKVIDVIKLKLNKFNSNVSEELELEDVDITDELNSDPDKQKD 257
D KKY + K ++NK NVS ++ D N+D DK+K+
Sbjct 2752 SNDFSINEEKKNNKDTKKYMISS--KEEINKEIENVSNQM--------DNKNNDVDKKKN 2801
Query 258 ELDKEDI 264
++E I
Sbjct 2802 ISNEEII 2808
Score = 34.7 bits (78), Expect = 4e-04
Identities = 59/283 (21%), Positives = 114/283 (40%), Gaps = 35/283 (12%)
Query 18 DLLDAQKGKISKEKLLDFLQERGIFCSE-NETRNALHERIAALSIDWFLIEDILSLAASK 76
+ +D K KIS+ +LD G+ CS+ N + + D +IE+ ++ SK
Sbjct 2956 EFIDISKDKISEHNILDESFNSGVVCSDKNRKDQVVFIDGDVKNNDISIIEENVTYYTSK 3015
Query 77 ENFQKVTATNFTLPKADALETTLENLKSQLSNKDFIVDKLKNGNYEIQYKVDKIEKNNAR 136
E N L +E+T E + + +KL+ N E++ + NN
Sbjct 3016 E-----VNNNSVLKNERDVESTSE---LYIGGDKHVYNKLETDNAEMESNNNNNNNNN-- 3065
Query 137 LIQRTSKDEKISINLDGDQATIVNTVGEG----------TDTVVQTFFNELERNSKTEIK 186
+ + N+ VNT+ + + Q + N K +K
Sbjct 3066 -------NSDCNNNVSTLSTAAVNTINRSHMSPQKNDNDMNKINQDDIIHTKMNDKKNVK 3118
Query 187 NTSINFSSIIDNTIINKYFLDLIKIDAKKYKVIDVIKLKLNKFNSNVSEELELEDVDITD 246
+ + N +++ +N N LD I K++ VI + KL K N N + E + I +
Sbjct 3119 DDNGNMTNLNNNIDKNDRNLDTI---LKEHSVI-MQKLDELKENRNKEHDGEFYNNLILN 3174
Query 247 E---LNSDPDKQKDELDKEDIKSALISGSSLLASNLFKVLSNK 286
++S ++ E++K+ I + + + ++++L NK
Sbjct 3175 NQFLIHSFKVEEGVEINKDSIIINKKMFNKYILNKIYELLDNK 3217
Score = 28.1 bits (61), Expect = 0.040
Identities = 45/225 (20%), Positives = 88/225 (39%), Gaps = 34/225 (15%)
Query 128 DKIEKNNARLIQRTSKDEKISINLDGDQATIVNTVGEGTDTV---VQTFFNELERNS--- 181
D+I ++N + + + K K+ N + ++ D + T NE +
Sbjct 4189 DEINEDNKKDVTKQQKKRKL--NSVSKKDMLIKKEMNADDNINCKENTLQNESPKKDDEL 4246
Query 182 -KTEIKNTSINFSSIIDNTIINKYFLDLIKIDAKKYKVIDVIKLKLNKFNSNVSEELELE 240
+ ++K T+ N S N + +K F +D KK + + V K NV+ ++EL+
Sbjct 4247 RENDLKTTTENIKS---NEVEDKEF-----VDKKKKRKLSV------KVKVNVNVKVELQ 4292
Query 241 DVDITDELNSDPDKQKDELDKEDIKSALISGSSLLASNLFKVLSNKGYFISSIAWLVLEK 300
D + + K+K++ +K++ + KV K +E+
Sbjct 4293 DTENDENKEKGIKKEKNDEEKKNDAEKKKKENKKGREKSVKVRKTKNQ-------TQVER 4345
Query 301 TGEKRKIEYSSGFTDPDKRDIFTFESKGFFEINSATQDYKKNRTT 345
EK + T+ DI ++ IN+ T D N+T+
Sbjct 4346 ENEKENL--MENVTNDKTSDIINNKTSDI--INNKTSDIINNKTS 4386
Score = 26.9 bits (58), Expect = 0.091
Identities = 31/146 (21%), Positives = 60/146 (41%), Gaps = 21/146 (14%)
Query 73 AASKENFQKVTATNFTLPKADALETTLENLKSQLSNKDFIVDKLKNGNYEIQYKVDKIEK 132
A+ NF+ NF K + + N+K+ ++N + I++ + N N + ++ I
Sbjct 3400 ASYNNNFENNLENNFVNNKMN----NMNNMKNNMNNMNNIMNNIMNNN--MNNIMNNIMN 3453
Query 133 NNARLIQRTSK--DEKISINLD----GDQATIVNT-------VGEGTDTVVQTFFNELER 179
NN I + + +S N+D DQ I N+ + + F N +
Sbjct 3454 NNMNNIINNNNIFNNDVSNNVDMQHKSDQICIFNSNNIHSVPIFNNKPYMDNNFNNMVLV 3513
Query 180 NSKTEIKNTSI--NFSSIIDNTIINK 203
N +I I N ++ + ++ NK
Sbjct 3514 NKSNDINGDDILCNMKNLYNKSVCNK 3539
Score = 26.9 bits (58), Expect = 0.091
Identities = 48/191 (25%), Positives = 84/191 (44%), Gaps = 25/191 (13%)
Query 96 ETTLENL-KSQLSNKDFIVDKLKNGNYEIQYKVDKIEKNNARLIQRTSKDEKISINLDGD 154
+ ++ENL K K+F+ + N N +Q N LI + S++ + D D
Sbjct 5980 DKSVENLIKGYFILKNFL--HIGNNNITLQ--------NEDLLILKKSENSFVHNLYDND 6029
Query 155 QATIVNTVGEGTDTVVQTFFNELERN---SKTEIKNTSINFSSIIDNTIINKYFLDLIKI 211
+ V+ T + ++ N+ E + +K+ KN+ + +SI+DN +K + KI
Sbjct 6030 KVYNVHVPYVYTKKMNTSYMNKKENDKKYNKSVNKNSCKSKNSILDNINFDK---NKNKI 6086
Query 212 DAKKYKVIDVIKLKLNKFNSNVSEELELEDVDITDELNSDPDKQKDELD-KEDIKSALIS 270
KKY + N++ ++ S E E+ DE N + + D+ + E IK I
Sbjct 6087 -TKKYTAFIIDN---NEYTTDCSNE---ENNTSDDEENENRKNENDDDNIPEHIKMNNIM 6139
Query 271 GSSLLASNLFK 281
S N FK
Sbjct 6140 NSQQKKENDFK 6150
Score = 26.6 bits (57), Expect = 0.12
Identities = 53/238 (22%), Positives = 98/238 (41%), Gaps = 38/238 (16%)
Query 55 RIAALSIDWFLIEDILSLAASKENFQKVTATNFTLPKADALETTLENLKSQLSNKDFIVD 114
+I L + + + IL++ S ++ + TN P A+ T L++ F++
Sbjct 314 KIYELFFNKYKKKKILNIECSGNKYKGLLRTNHFPPYANFNFTIRRKLQTSNVLGHFMIS 373
Query 115 KLKNGNYEIQYK-----VDKIEKNNA-RLIQRTSKDEKISINLDGDQATIVNTVGEGTDT 168
K N N I Y+ V+K + N R+I K E + ++ G + N V
Sbjct 374 KC-NFNRTICYRKYIKCVNKYKNNKRNRVINMYVKKENVD-SIKGTFGNMNNGVHHNNSR 431
Query 169 --VVQTFFNELERNSKTEIK------NTSINFSSII-DNTIINKYFLDLIKIDAKKYKVI 219
+ T N + N+ +K N +F +I ++T +++ + IK +K +
Sbjct 432 RRLNNTSKNNISNNNNNMLKKKKGKKNYKGSFDQMIQEDTTLDQAKKESIKTVSKNERKN 491
Query 220 DVIK-------LKLNKFNSN--------------VSEELELEDVDITDELNSDPDKQK 256
++ K KLNK SN +E+ +E + T+E+N D K+K
Sbjct 492 NMNKHSHDNKVSKLNKRMSNKRRNNKNCNPSNDMCNEDDVIEKICTTEEVNDDEKKKK 549
Score = 26.2 bits (56), Expect = 0.16
Identities = 13/38 (34%), Positives = 22/38 (58%), Gaps = 1/38 (3%)
Query 87 FTLPKADALETTLENLKSQLSNKDFIVDKLKN-GNYEI 123
+ + + + +EN+ +Q+ NK+ VDK KN N EI
Sbjct 2770 YMISSKEEINKEIENVSNQMDNKNNDVDKKKNISNEEI 2807
Score = 25.4 bits (54), Expect = 0.27
Identities = 45/189 (24%), Positives = 70/189 (37%), Gaps = 29/189 (15%)
Query 108 NKDFIVDKLKNGNYEIQYK---VDKIEKNNARLIQRTSKDEKIS--------INLDGDQA 156
NKD I + K N + K V+K E+++ +D KI +N+D D
Sbjct 744 NKDNISESSKRSNNIGEKKMLHVEKSEEHDDMTSDSNKEDTKIEEGRKKSNEVNIDVDD- 802
Query 157 TIVNTVGEGTDTVVQTFFNELERNSKTEIKNTSINFSSIIDNTIINKYFLDLIKIDAKKY 216
GE + V N N + + N D +K I+ KY
Sbjct 803 ------GEEEENVNNNDNNNDNNNDNDNSSDNNNNDDGSNDTESCSK-------INKSKY 849
Query 217 KVIDVIKLKLNKFNSNVSEELELEDVDITDELNSDPDKQKDELDKEDIKSALISGSSLLA 276
K + +K N + N+S+ LN K D+ K + K+ I G+S
Sbjct 850 KGKEKKDVKENTDDKNLSDSNSNNSKKKFKVLNKAIKKDNDKKKKYEKKN--IEGNS--N 905
Query 277 SNLFKVLSN 285
+N+ V SN
Sbjct 906 NNMILVRSN 914
Score = 25.4 bits (54), Expect = 0.27
Identities = 51/228 (22%), Positives = 82/228 (36%), Gaps = 57/228 (25%)
Query 96 ETTLENLKSQLSNKDFIVDKLKNGNYEIQYKVDKIEKNNARLIQRTSK------------ 143
++T N ++ NK DK KNG +I K +K +K N I + K
Sbjct 973 DSTKLNCVKKVKNKS--TDK-KNGKSKINIKNEKKKKINNSKINKGRKGINKKDKGKGDD 1029
Query 144 ---------DEK---ISINLDGDQATIVNTVGEGTDTVVQTFFNELERNSKTEIK-NTSI 190
DEK + D ++ E T V T N N K ++K +
Sbjct 1030 NNYVCLIYDDEKKFYFNFKKFKDIINVIKGSDESTRFYVDTNNNNHNNNMKKKMKLFKKV 1089
Query 191 NFSSIIDNTIIN---------KYFLDLIKIDAKKYKV--------IDVIKLKLNKFNSNV 233
S ++N I+ K+F +I+ + Y + V K KLNK V
Sbjct 1090 EKSLYLENLDIDTDEILFRRPKFFNCIIEESFENYDINYEGEDGNFYVFKNKLNKIRKKV 1149
Query 234 SEELELEDVDITDELNSDP------------DKQKDELDKEDIKSALI 269
+ + E + D+ EL + + +KD K +K +I
Sbjct 1150 TIKNETDSSDMYIELKDEEKGFKYIGYRVSFELKKDNKKKAQVKVGII 1197
Score = 24.6 bits (52), Expect = 0.47
Identities = 54/281 (19%), Positives = 107/281 (38%), Gaps = 40/281 (14%)
Query 85 TNFTLPKADALETTLENLKSQLSNKDFIVDKLKNGNYEIQYKVDKIEKNNARLIQRTSKD 144
TN T D++ L ++ + +N + + ++ G I+ I K +I +
Sbjct 1993 TNMTCVNMDSINKNLNDMNNNNNNNNKM--EVFCGQNNIKLNEYYINKEGYNIISNDN-- 2048
Query 145 EKISINLDGDQATIVNTVG-EGTDTVVQTFFNELERNSKTEIKNTSINFSSIIDNTIINK 203
N++ D V +G + T + + + N K IN SSI + N
Sbjct 2049 -----NMNYDNYNNVQNIGMKKMYTNINDYNSSNVPNESVYNKENFINNSSIYNINENNT 2103
Query 204 YFLDLIK--IDAKKYKVIDVIKL-KLNKFNSNVSEELELEDVDITDELNSDPDKQKDE-- 258
Y L+ K I KY + + +N + + + + + N++ + K+
Sbjct 2104 YDLNCDKKLIFDNKYNLSAYQNEGDIMNYNGMYQKNINISNPPYNNNNNNNNNMVKEGEK 2163
Query 259 --LDKEDIKSALISGSSLLASNLFKVLSNKGYFISSIAWLVLEKTGEKRKIE-YSSGFTD 315
L+ +D+ + IS + + +N + + KRK+E Y T
Sbjct 2164 YILNNDDMNNISISKDNDINNNCNNIAN----------------IYRKRKLEQYKKDITQ 2207
Query 316 PDKRDIFTFESKGFFEINSATQDYKKNRTTWKSNQRKMIEF 356
+ ++F F++ FF IN K + SN +I++
Sbjct 2208 YELYELFDFKNDSFF-INR-----NKEMFSCSSNDHNLIDY 2242
Score = 24.3 bits (51), Expect = 0.62
Identities = 38/188 (20%), Positives = 73/188 (39%), Gaps = 23/188 (12%)
Query 95 LETTLENLKSQLSNKD-FIVDKLKNGNYEIQYKVDKIEKNNARLIQRTSKDEKISINLDG 153
+E +EN K++++N D F + N N + + I NN ++ + + I +N DG
Sbjct 1931 IEDCVENYKNEINNLDSFQIGHDNNNNND-----NNINNNNK--MEGVNNESVIFMN-DG 1982
Query 154 DQATIVNTVGEGTDTVVQTFFNE-LERNSKTEIKNTSINFSSIIDNTIINKYFLDLIKID 212
+ N G V N+ L + N + +N +N+Y+ I+
Sbjct 1983 CNNKLYNKEGTNMTCVNMDSINKNLNDMNNNNNNNNKMEVFCGQNNIKLNEYY-----IN 2037
Query 213 AKKYKVIDVIKLKLNKFNSNVSEELELEDVDITDELNSDPDKQKDELDKEDI--KSALIS 270
+ Y +I N N N ++++ + + D + E + K I+
Sbjct 2038 KEGYNIIS------NDNNMNYDNYNNVQNIGMKKMYTNINDYNSSNVPNESVYNKENFIN 2091
Query 271 GSSLLASN 278
SS+ N
Sbjct 2092 NSSIYNIN 2099
Score = 24.3 bits (51), Expect = 0.62
Identities = 21/88 (24%), Positives = 35/88 (40%), Gaps = 4/88 (5%)
Query 109 KDFIVDKLKNGNYEIQYKVDKIEKNNARLIQRTSKDEKISINLDGDQATIVNTVGEGTDT 168
K+ I L N N+E ++ I+ NN ++ E+I +D N E
Sbjct 2426 KNVISSNLCNNNFEKYVNINSIDHNNMSGEKKRKSVEEIMSVVDNKSYYGFNKCSE---- 2481
Query 169 VVQTFFNELERNSKTEIKNTSINFSSII 196
+ NE +R K E K + + I+
Sbjct 2482 YILYSSNEYDRAKKKENKRIKLLKNDIL 2509
Score = 24.3 bits (51), Expect = 0.62
Identities = 10/34 (29%), Positives = 19/34 (56%), Gaps = 0/34 (0%)
Query 249 NSDPDKQKDELDKEDIKSALISGSSLLASNLFKV 282
N+D K + +D ED+++ L G ++ N K+
Sbjct 5768 NNDKMKGDNNIDNEDVRNVLCDGEERVSYNRNKL 5801
Score = 23.1 bits (48), Expect = 1.4
Identities = 24/88 (27%), Positives = 36/88 (41%), Gaps = 6/88 (7%)
Query 175 NELERNSKTEIKNTSINFSSIIDNTIINKYFLDLIKIDAKKYKVIDVIKLKLNKFNSNVS 234
N N+ N + N ++ +N NK + K KK V DV K+N+ NSN
Sbjct 5373 NNNNNNNNNNNNNNNNNNNNNNNNNNNNKSKKNTQK---KKDHVNDV---KINQNNSNNK 5426
Query 235 EELELEDVDITDELNSDPDKQKDELDKE 262
+ + +EL SD K D +
Sbjct 5427 NNKKKKTSKDNEELKSDNTKNNKTKDSD 5454
Score = 23.1 bits (48), Expect = 1.4
Identities = 31/127 (24%), Positives = 53/127 (42%), Gaps = 22/127 (17%)
Query 101 NLKSQLSN--KDFIVDKLKNGNYEIQYKVDKIEKNNARLIQRTSKDEKISINL------D 152
NL QL+N K ++KL+ + + K + + N + + +E + N+ D
Sbjct 6153 NLYFQLTNVIKKVSINKLEGNFFNYEEKGNLLGSN----VSKIKMNELLECNVGEENFCD 6208
Query 153 GDQATIVNTVGEGTDTVV-------QTFFNELERNSKTEIKNTSIN-FSSIIDNTIINK- 203
DQ N D QT F + T N ++N + ++N +INK
Sbjct 6209 DDQKFSDNKNYASDDEEKKKKKRKNQTRFYNYPKRISTTNNNKNVNVLVNSLNNNLINKK 6268
Query 204 -YFLDLI 209
YFL++I
Sbjct 6269 EYFLNII 6275
Score = 22.7 bits (47), Expect = 1.8
Identities = 15/61 (25%), Positives = 21/61 (34%), Gaps = 11/61 (18%)
Query 131 EKNNARLIQRTSKDEKISINLDGDQATIVNTVGEGTDTVVQTFFNELERNSKTEIKNTSI 190
E+N + I K+ +NLD D + N L+ N IKN
Sbjct 5300 EENKNKTIVNNDNGTKVDVNLD-----------NADDIINNNNMNMLDNNMNGPIKNNEE 5348
Query 191 N 191
N
Sbjct 5349 N 5349
Score = 21.9 bits (45), Expect = 3.2
Identities = 11/33 (33%), Positives = 15/33 (45%), Gaps = 0/33 (0%)
Query 329 FFEINSATQDYKKNRTTWKSNQRKMIEFAFQKY 361
F++ + YK T SN K+ E F KY
Sbjct 291 FYDESINDYPYKNLEKTTFSNSSKIYELFFNKY 323
Score = 21.9 bits (45), Expect = 3.2
Identities = 22/102 (22%), Positives = 44/102 (43%), Gaps = 14/102 (14%)
Query 100 ENLKSQLSNKDFIVDKLKNGNYEIQYKVDKIEKNNARLIQRTSKDEKISINLDGDQATIV 159
EN + N D D +KN +I+ DK ++N + T + + S N+D + ++
Sbjct 1574 ENKNGDIKNDDIKNDDIKND--DIRNDDDKNDENE----ENTKECKNESNNIDNNNSS-- 1625
Query 160 NTVGEGTDTVVQTFFNELERNSKTEIKNTSINFSSIIDNTII 201
D++ N+ SK + IN+ ++++ I
Sbjct 1626 ------NDSLSDVDNNKDNGKSKNKKYRRCINYIPSVEHSDI 1661
Score = 21.9 bits (45), Expect = 3.2
Identities = 26/126 (21%), Positives = 49/126 (39%), Gaps = 9/126 (7%)
Query 115 KLKNG---NYEIQYKVDKIEKNNARLIQRTSKDEKISINLDGDQATIVNT---VGEGTDT 168
K+ NG N Y I N + + R S++++ NT + GTD
Sbjct 3563 KIWNGDITNKSKTYTYTNINNNGSVIDYRKWSSVNRSVSMNNMNCIRSNTNPRILSGTDH 3622
Query 169 VVQTFFNELERNSKTEIKNTSINFSSIIDNTIINKYFLDLIKIDAKKYKVIDVIKLKLNK 228
+++ N ++N + ++NT F+ KI + + + K+NK
Sbjct 3623 ILKNNHMNKRNNVNNTYGVNNVNNVNNVNNTNNVSCFMMRRKIRSNS---LHDMNDKMNK 3679
Query 229 FNSNVS 234
N N++
Sbjct 3680 MNDNIN 3685
Score = 21.6 bits (44), Expect = 4.2
Identities = 14/48 (29%), Positives = 26/48 (54%), Gaps = 4/48 (8%)
Query 103 KSQLSNKDFIVDKLKNGNYEIQYKV---DKIEKN-NARLIQRTSKDEK 146
K +SN++ I+D KN ++ V + ++K+ NA I++ EK
Sbjct 2799 KKNISNEEIILDNTKNSCHDNDSNVLYNESVKKSFNACKIEKKEGIEK 2846
Score = 21.2 bits (43), Expect = 5.5
Identities = 20/76 (26%), Positives = 31/76 (41%), Gaps = 19/76 (25%)
Query 174 FNELERNSKTEIKNTSINFSSIIDNTIINKYFLDLIKIDAKKYKVIDVIKLKLNKFNSNV 233
FN + R+S T K+T ++ YF ID +Y K + N NV
Sbjct 3848 FNSMRRSSSTPKKSTG----------LLKNYF----NIDIDQYN-----KTNSHIMNYNV 3888
Query 234 SEELELEDVDITDELN 249
S ++ +V I + N
Sbjct 3889 SINNDMNNVYINNNNN 3904
Score = 20.8 bits (42), Expect = 7.2
Identities = 22/95 (23%), Positives = 44/95 (46%), Gaps = 16/95 (17%)
Query 71 SLAASKENFQKVTATN-----FTLPKADALETTLENLKSQLSNKDF----------IVDK 115
SL + ++N + V TN T P + ++ + ++ S SNK+ +
Sbjct 5157 SLHSKEDNKKDVIITNNASIDSTSPSINMNKSVVSSIYSYNSNKEKKKNMRKCIKGLHHT 5216
Query 116 LKNG-NYEIQYKVDKIEKNNARLIQRTSKDEKISI 149
+KN N ++ +DK + ++ I+ +KD K +I
Sbjct 5217 IKNKLNLYVKLMLDKYIQESSNYIKNENKDIKKTI 5251
>G4SLH0 Titin homolog [Caenorhabditis elegans]
Length=18562
Score = 37.0 bits (84), Expect = 7e-05
Identities = 38/156 (24%), Positives = 66/156 (42%), Gaps = 26/156 (17%)
Query 126 KVDKIEKNNARLIQRTSKDEKISINLDGD---------QATIVNTVGEG----------T 166
K+ K K + + D +I++ + D ++TI +T E T
Sbjct 9084 KLKKKSKKSKKTTDEPELDSEIALEVSSDITSSLEITTESTIPDTAPESQETLNVEIAVT 9143
Query 167 DTVVQTFFNELERNSKTEIKNTSINFSSII--DNTIINKYFLDLIKIDAKKY----KVID 220
+T VQ N + ++K ++ N SSI+ D+ +NK L + KK
Sbjct 9144 ETTVQKITNPSDESAKKDV-NEDTAVSSIVKKDDKDVNKKSLPESGLTTKKEIQGKPEKK 9202
Query 221 VIKLKLNKFNSNVSEELELEDVDITDELNSDPDKQK 256
++K K K +S++SE E D+T S+P+ K
Sbjct 9203 IMKKKTEKADSSISETSETLTKDLTQTKQSEPEPAK 9238
Score = 30.4 bits (67), Expect = 0.008
Identities = 28/96 (29%), Positives = 42/96 (44%), Gaps = 20/96 (21%)
Query 258 ELDKEDIKSALISGSSL--LASNLFKVLSNKGYFISSIAWLVLEKTGEKRKIEYSSGFTD 315
E+D E I A I G+SL L K LSN + +S+ K E RKIE + TD
Sbjct 4465 EIDGEKIPDAYIEGNSLSIKVDTLSKKLSNVSFKVSASE----GKVFETRKIEIAQEDTD 4520
Query 316 PDKRDI--------------FTFESKGFFEINSATQ 337
+ +I +TFE+ ++ N + +
Sbjct 4521 EENFEINYSLRIDEQSGNTTYTFENSELYQGNQSRE 4556
Score = 27.3 bits (59), Expect = 0.070
Identities = 36/186 (19%), Positives = 75/186 (40%), Gaps = 16/186 (9%)
Query 93 DALETTLENLKSQLSNKDFIVDKLKNGNYEIQYKVDKIEKNNARLIQRTSKDEKISINLD 152
D+ + ++ +K ++S K + KN + E++ ++ E+ + +++ D +
Sbjct 11277 DSDKMSITGIKKKMSQKSESAEAQKNESPEVK-EISSFEEKTLKSKKKSKADRNQGTEAN 11335
Query 153 GDQATIVNTVGEGTDTVVQTFFNELERNSKTEIK--NTSINFSSIIDNTIINKYFLDLIK 210
TI TD +E ++ IK N S +S D ++ ++ LD +
Sbjct 11336 LGDKTIDKDYLSVTDKNQSLEKSEASGQAEKSIKAPNKSKVTTSFADESLTSE--LDRLM 11393
Query 211 ID--------AKKYKVIDVIKLKLNKFNSNVSEELELEDVDITDELNSDPDKQKDELDKE 262
D A++ K D++ + N SE+ E +++ + + K D L
Sbjct 11394 ADEEMAEMMFAEEEKAADLLNVMNKNKGLNKSEQEESQEISLKSQ---SKVKDSDSLSST 11450
Query 263 DIKSAL 268
D K L
Sbjct 11451 DKKIGL 11456
Score = 25.4 bits (54), Expect = 0.27
Identities = 20/79 (25%), Positives = 36/79 (46%), Gaps = 4/79 (5%)
Query 78 NFQKVTATNFTLPKADALETTLENLKSQLSNKDFIVDKLKNGNYEIQYKVDKIEKN---- 133
+F++ T + KAD + T NL + +KD++ KN + E + EK+
Sbjct 11312 SFEEKTLKSKKKSKADRNQGTEANLGDKTIDKDYLSVTDKNQSLEKSEASGQAEKSIKAP 11371
Query 134 NARLIQRTSKDEKISINLD 152
N + + DE ++ LD
Sbjct 11372 NKSKVTTSFADESLTSELD 11390
Score = 24.3 bits (51), Expect = 0.62
Identities = 16/62 (26%), Positives = 26/62 (42%), Gaps = 5/62 (8%)
Query 91 KADALETTLENLKSQLSNKDFIVDKLKNGNYEIQYKVDKIEKNNARLIQRTSKDEKISIN 150
K+D +T E+ S S + D Q + DK +K A + + S DEK +
Sbjct 9552 KSDTSKTVAESAGSSESETQKVADATSK-----QKETDKKQKLEAEITAKKSADEKSKLE 9606
Query 151 LD 152
+
Sbjct 9607 TE 9608
Score = 23.9 bits (50), Expect = 0.82
Identities = 20/69 (29%), Positives = 31/69 (45%), Gaps = 10/69 (14%)
Query 211 IDAKKYKVIDVIKLKLNKFNSNVSEELELEDVDITDELNS--------DPDKQKDELDKE 262
+D K K V+K K K +S +SE E V+ S D +K++ E D++
Sbjct 9328 VDEKPKK--KVLKKKTEKSDSTISETSETSAVESAGPSESETQNVAAVDKEKKQKETDEK 9385
Query 263 DIKSALISG 271
A I+G
Sbjct 9386 QKLEAEIAG 9394
Score = 23.9 bits (50), Expect = 0.82
Identities = 35/189 (19%), Positives = 75/189 (40%), Gaps = 18/189 (10%)
Query 91 KADALETTLENLKSQLSNKDFIVDKLKNGNYEIQYKVDKIEKNNARLIQRTSKDEKISIN 150
K++ +T +E+ S + D + Q + D+ +K A + + S DEK +
Sbjct 13435 KSETSKTVVESAGPSESETQKVADAARK-----QKETDEKQKLEAEITAKKSADEKSKLE 13489
Query 151 LDGD--QATIVNTVGEGTDTVVQTFFNELERNSKTEI------KNTSINFSSIIDNTIIN 202
+ +A V + + Q + + K K + I ++ +D
Sbjct 13490 AESKLKKAAEVEAAKKQKEKDEQLKLDTEAASKKAAAEKLELEKQSHIKKAAEVDAVKKQ 13549
Query 203 KYFLDLIKIDAKKY-KVIDVIKLKLNKFNSNVSE----ELELEDVDITDELNSDPDKQKD 257
K + +++++ K D KLKL + +E E++ E + E + D+ K
Sbjct 13550 KELEEKQRLESEAATKKADAEKLKLEEQKKKAAEIALIEIQKEQEKLAQEQSRLEDEAKK 13609
Query 258 ELDKEDIKS 266
+K+ ++S
Sbjct 13610 SAEKQKLES 13618
Score = 23.5 bits (49), Expect = 1.1
Identities = 38/195 (19%), Positives = 76/195 (39%), Gaps = 14/195 (7%)
Query 72 LAASKENFQKVTATNFTLPKADALETTLENLKSQLSNKDFIVDKLKNGNYE---IQYKVD 128
L K++ K A + K LE + L+S+ + K +KLK + + +
Sbjct 13529 LELEKQSHIKKAAEVDAVKKQKELEEK-QRLESEAATKKADAEKLKLEEQKKKAAEIALI 13587
Query 129 KIEKNNARLIQRTSKDEKISINLDGDQATIVNTVGEGTDTVVQTFFNELERNSKTEIKNT 188
+I+K +L Q S+ E + Q T + T+ + +E + K K T
Sbjct 13588 EIQKEQEKLAQEQSRLEDEAKKSAEKQKLESETKSKQTEEAPKESVDEKPKK-KVLKKKT 13646
Query 189 SINFSSIIDNTIINKYFLDLIKIDAKKYKVIDVIKLKLNKFNSNVSEELELEDVDITDEL 248
+ SSI + K +D + + +++ V + + D + +
Sbjct 13647 EKSDSSISQKSKSAKSTVDAAETLESDFNLVE---------KKTVQKVEQSPDESTSATI 13697
Query 249 NSDPDKQKDELDKED 263
DP ++ +E+ K+D
Sbjct 13698 KRDPAQKTEEISKQD 13712
Score = 22.7 bits (47), Expect = 1.9
Identities = 30/149 (20%), Positives = 62/149 (42%), Gaps = 14/149 (9%)
Query 131 EKNNARLIQRTSKDEKISINLDGDQATIVNTVGEGTDTVVQTFFNELERNSKTEIKNTSI 190
++++ IQ +K K +DG + I +G V EL ++ +++N S
Sbjct 10915 QESDKMSIQALNKSMKKKDGVDGVEGNINIGRSDGDQLSVNDIDAEL--STSEQVENASQ 10972
Query 191 NFSSIIDNTIINKYFLDLIKIDAKKYKVIDVIKLKLNKFNS--------NVSEELELEDV 242
N + D+ + L +K K + + KL + S ++ EEL+ ++
Sbjct 10973 NLGATADSDG-DSLSLQTLKKRISKKGIHGEAESKLGEKQSGSDSFTLQDLYEELKAKED 11031
Query 243 DI---TDELNSDPDKQKDELDKEDIKSAL 268
+ + N+D +K L+ D+K +
Sbjct 11032 AVEAGAETSNADQSAEKTSLEVRDMKKKM 11060
Score = 22.3 bits (46), Expect = 2.4
Identities = 29/115 (25%), Positives = 51/115 (44%), Gaps = 14/115 (12%)
Query 175 NELERNSK--TEIKNTSINFSSIIDNTIINKYFLDL--IKIDAKKYKVIDVIKLKLNKFN 230
N +ERNSK + K N ++ ++ +D+ IK + K ++I +
Sbjct 1957 NTVERNSKAGAKAKGEVENLKKCVETLLLFDAEMDMKDIKESSPKKEIISKKDQQSLDDQ 2016
Query 231 SNVSEELELEDV--DITDELNSDPDKQKD-------ELDKEDIKSALISGSSLLA 276
V++++ L+DV D+ + P K D EDI++A+ S S LA
Sbjct 2017 IKVTQQI-LKDVERDLNKMERTSPGKSLSPNKRTFAPKDVEDIEAAIFSISDQLA 2070
Score = 22.3 bits (46), Expect = 2.4
Identities = 25/98 (26%), Positives = 47/98 (48%), Gaps = 12/98 (12%)
Query 159 VNTVGEGTDTVVQTFFNELERNSKTEIKNTSINFSSI----IDNTIINKYFLDLIKIDAK 214
VN GEG + + +E N+ + S +F+ +D+ +N + I I+
Sbjct 9022 VNGFGEGAPSEI------IEVNTLDYDQEESFDFAGEEELKLDDVQVNNEVVTEITIEES 9075
Query 215 KYKVIDVIKLKL-NKFNSNVSEELELEDVDITDELNSD 251
+ + + KLK +K + ++E EL D +I E++SD
Sbjct 9076 EVTIEEHRKLKKKSKKSKKTTDEPEL-DSEIALEVSSD 9112
Score = 22.3 bits (46), Expect = 2.4
Identities = 9/29 (31%), Positives = 20/29 (69%), Gaps = 0/29 (0%)
Query 235 EELELEDVDITDELNSDPDKQKDELDKED 263
EEL+L+DV + +E+ ++ ++ E+ E+
Sbjct 9053 EELKLDDVQVNNEVVTEITIEESEVTIEE 9081
Score = 21.9 bits (45), Expect = 3.2
Identities = 38/184 (21%), Positives = 82/184 (45%), Gaps = 16/184 (9%)
Query 91 KADALETTLE-NLKSQL-SNKDFIVDKLKNGNYEIQYKVDKIEKNNARLIQRTSKDEKIS 148
+ADA++ E + K++L +NK +KLK +E+ Q K +
Sbjct 9701 EADAVKKQKELDEKNKLEANKKSAAEKLKLEEESAAKSKQTVEEQAKLDAQTKEKTAEKQ 9760
Query 149 INLDGDQATIVNTVGEGTDTVVQTFFNELERNSKTEIKNTSINFSSIIDNTIINKYFLDL 208
L+ D + ++ E +TV + ++ + KTE ++SI+ S+ T++
Sbjct 9761 TGLEKDDKSTKDS--ESKETVDEKPKKKVLKK-KTEKSDSSISQKSVTSKTVVESGG--- 9814
Query 209 IKIDAKKYKVIDVIKLKLNKFNSNVSEELELEDVDITDELNSDPDKQKDELDKEDIKSAL 268
+++ KV D + ++E + + +IT + ++D +K K E + + K+A
Sbjct 9815 -PSESETQKVADAAR------KQKETDEKQKLEAEITAKKSAD-EKSKLEAESKLKKAAE 9866
Query 269 ISGS 272
+ +
Sbjct 9867 VEAA 9870
Score = 21.9 bits (45), Expect = 3.2
Identities = 41/211 (19%), Positives = 76/211 (36%), Gaps = 43/211 (20%)
Query 66 IEDILSLAASKENFQKVTATNFT----------LPKADALETTLENLKSQLSNKDFIVDK 115
+ED +A K+ + T + T PK L+ E S +S K
Sbjct 13603 LEDEAKKSAEKQKLESETKSKQTEEAPKESVDEKPKKKVLKKKTEKSDSSISQKSKSAKS 13662
Query 116 LKNGNYEIQYKVDKIEKNNARLIQRTSKDEKISINLDGDQATIVNTVGEGTDTVVQTFFN 175
+ ++ + +EK + +++ S DE S + D A + + D
Sbjct 13663 TVDAAETLESDFNLVEKKTVQKVEQ-SPDESTSATIKRDPAQKTEEISKQDDGD------ 13715
Query 176 ELERNSKTEIKNTSINFSSIIDNTIINKYFLDLIKIDAKKYKVIDVIKLKLNKFNSNVSE 235
E+ + T+ K D++ V+K K K +S V+
Sbjct 13716 --EKKTTTDGKPPKPE--------------------DSEATPKKRVVKKKTQKSDS-VAS 13752
Query 236 ELELEDVD-ITDELNSDPDKQ--KDELDKED 263
+ L DV ++D++ P K+ K + +K D
Sbjct 13753 DASLADVSKLSDDVEEKPKKKVLKKKTEKSD 13783
Score = 21.9 bits (45), Expect = 3.2
Identities = 16/53 (30%), Positives = 28/53 (53%), Gaps = 13/53 (25%)
Query 229 FNSNVSEELELE---DVDITDELNSDPDKQKDELDKEDIKSALISGSSLLASN 278
FNS+ SE E+E D+++T E++ D+E + + G L+AS+
Sbjct 14548 FNSSFSELTEIEEGHDIELTCEVS----------DEEAVVNWYKDGKKLVASD 14590
Score = 21.6 bits (44), Expect = 4.2
Identities = 54/272 (20%), Positives = 108/272 (40%), Gaps = 28/272 (10%)
Query 5 KFDSLVISDRDIIDLLDAQKGKISKEKLLDFLQERGIFCSENETRNALHERI--AALSID 62
K DS + +++ D K K D + ++ +E++T+ A ++ AA +
Sbjct 12875 KSDSSISQKSNVLKPADDDKSKS------DDVTDKSKKTTEDQTKVATDSKLEKAADTTK 12928
Query 63 WFLIEDILSLAASKENFQKVT--ATNFTLPKADALETTLENLKSQLSNKDFI--VDKLKN 118
E ++ + K+ +K T + +F K++ +E K S I V+K K
Sbjct 12929 QIETETVVDDKSKKKVLKKKTEKSDSFISQKSET-PPVVEPTKPAESEAQKIAEVNKAKK 12987
Query 119 GNYEIQYKVDKIEKNNARLIQRTSKDEKISINLDGDQATIVNTVG----EGTDTVVQTFF 174
Q +VD K A + + DEK+ I + + + D ++
Sbjct 12988 -----QKEVDDNLKREAEVAAKKIADEKLKIEAEANIKKTAEVEAAKKQKEKDEQLKLET 13042
Query 175 NELERNSKTE----IKNTSINFSSIIDNTIINKYFLDLIKIDAKKYKVIDVIKLKLNKFN 230
+ + S E K I ++ D K + K++A K D KLKL + +
Sbjct 13043 EVVSKKSAAEKLELEKQAQIKKAAEADAVKKQKELNEKNKLEAAKKSAAD--KLKLEEES 13100
Query 231 SNVSEELELEDVDITDELNSDPDKQKDELDKE 262
+ S+++ E V +E + ++ +++ E
Sbjct 13101 AAKSKKVSEESVKFGEEKKTKAGEKTVQVESE 13132
Score = 20.4 bits (41), Expect = 9.5
Identities = 31/148 (21%), Positives = 56/148 (38%), Gaps = 24/148 (16%)
Query 129 KIEKNNARLIQRTSKDEKISINLDGDQATIVNTVGEGTDT-VVQTFFNELERNSKTEIKN 187
K+E+ R+I + +N + + NTV + T T F + R E N
Sbjct 4388 KLEETGTRIITCEVSNSSSKVNASCNVERVHNTVSDFVMTNDNSTRFLAVGRKCTRERNN 4447
Query 188 TSINFSSIIDNTIINKYFLDLIKIDAKKYK-----------VIDVIKLKLNKFNSNVS-- 234
T + + I D+ +ID +K +D + KL+ + VS
Sbjct 4448 TILKAVVVARENI-----GDICEIDGEKIPDAYIEGNSLSIKVDTLSKKLSNVSFKVSAS 4502
Query 235 --EELELEDVDITDELNSDPDKQKDELD 260
+ E ++I E D D++ E++
Sbjct 4503 EGKVFETRKIEIAQE---DTDEENFEIN 4527
Score = 20.4 bits (41), Expect = 9.5
Identities = 28/125 (22%), Positives = 54/125 (43%), Gaps = 10/125 (8%)
Query 70 LSLAASKENFQKVTATNFTLPKADALETTLENLKSQLSNKDFIVDKLKNGNY----EIQY 125
+ +A ++ QK+T + K D E T + + +KD L EIQ
Sbjct 9138 VEIAVTETTVQKITNPSDESAKKDVNEDTAVSSIVKKDDKDVNKKSLPESGLTTKKEIQG 9197
Query 126 KVDK--IEKNNARLIQRTSK-DEKISINLDGDQATIVNTVGEGTDTVVQTFFNELERNSK 182
K +K ++K + S+ E ++ +L + + T+T VQ +E++R ++
Sbjct 9198 KPEKKIMKKKTEKADSSISETSETLTKDLTQTKQSEPEPAKRTTETSVQ---DEVKRKTE 9254
Query 183 TEIKN 187
T K+
Sbjct 9255 TTSKS 9259
>A9CS50 Probable phenylalanine--tRNA ligase beta subunit [Enterocytozoon
bieneusi (strain H348)]
Length=566
Score = 36.6 bits (83), Expect = 8e-05
Identities = 44/169 (26%), Positives = 76/169 (45%), Gaps = 22/169 (13%)
Query 93 DALETTLENLKSQLSNKDFIVDKLKNGNYEIQYKVDKIEK------NNARLIQRTSKDEK 146
D L T+ +S ++ +DK NG I+YK K+ K N + I+ T K
Sbjct 121 DKLHQTIGRNRSAVAIGTHDLDKFYNGK-PIKYKTIKLNKLCFQPLNISTEIKGTELKTK 179
Query 147 ISINLDGDQATIVNTVGEGTDTVVQTFFNELERNSKTEIKNTSINFSSIIDNTIINKYFL 206
+ +L ++ +G + ++ + N + S I N+ FS I +T F+
Sbjct 180 LGCHLH----QYIDLLGSDEEGIIFEYDNHII--SMPPIINSE--FSKIEPST--TNIFI 229
Query 207 DLIKIDAKKYKVIDVIKLKLNKFNSNVSEELELE---DVDITDELNSDP 252
++ D K V V+KL L FN+ + E++E++ +DIT N P
Sbjct 230 EVTGTDYNK--VDQVLKLMLLNFNTGIIEQVEIQKENSIDITPVFNVTP 276
Score = 22.7 bits (47), Expect = 1.7
Identities = 15/47 (32%), Positives = 24/47 (51%), Gaps = 0/47 (0%)
Query 184 EIKNTSINFSSIIDNTIINKYFLDLIKIDAKKYKVIDVIKLKLNKFN 230
+I NT ++ SSII II K + +I+ K I ++ +FN
Sbjct 66 KIINTYLHGSSIISKPIIRKSSIKVIQESVSKRPFIACGIIRNARFN 112
>Q15075 Early endosome antigen 1 [Homo sapiens]
Length=1411
Score = 30.0 bits (66), Expect = 0.010
Identities = 38/186 (20%), Positives = 81/186 (44%), Gaps = 22/186 (12%)
Query 94 ALETTLENLKSQLSNKDFIVDKLKNGNYEIQYKVDKI-EKNNARLIQRTSKDEKISI--N 150
+LET++ L SQL+ +K+ + +I+ K + + A+ QR + N
Sbjct 618 SLETSVNELNSQLNESK---EKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQN 674
Query 151 LDGDQATIVNTVGEGTDTVVQTFFNELERNSKTEIKNTSINFSSIIDNTIINKYFLDLIK 210
D+ +N + D V ++ E S+ E + + +Y +
Sbjct 675 ALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLE--------------SHLKEYKEKYLS 720
Query 211 IDAKKYKVIDVIK-LKLNKFNSNVSEELELEDVDITDELNSDPDKQKDELDKE-DIKSAL 268
++ K ++ IK L+ + S+E L+D+ +LN+D + + EL K+ +++ +
Sbjct 721 LEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEI 780
Query 269 ISGSSL 274
+S + L
Sbjct 781 VSSTRL 786
Score = 28.1 bits (61), Expect = 0.038
Identities = 16/64 (25%), Positives = 30/64 (47%), Gaps = 0/64 (0%)
Query 91 KADALETTLENLKSQLSNKDFIVDKLKNGNYEIQYKVDKIEKNNARLIQRTSKDEKISIN 150
+ A ET+L + +LS K KLK E++ K ++ +L Q+ + E+ +
Sbjct 352 RLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQ 411
Query 151 LDGD 154
L +
Sbjct 412 LQSE 415
Score = 26.9 bits (58), Expect = 0.087
Identities = 61/302 (20%), Positives = 121/302 (40%), Gaps = 40/302 (13%)
Query 21 DAQKGKISKEKLLDFLQERGIFCSENETRNALHERIAALSIDWFLIEDILSLAASKENFQ 80
D+ + K SKE+ L LQ+ + + L R LS + ++I+S +++ + Q
Sbjct 738 DSLEVKASKEQALQDLQQ------QRQLNTDLELRATELSKQLEMEKEIVS--STRLDLQ 789
Query 81 KVTATNFTLPKADALETTLENLKSQLSNKDFIVDKLKNGNYEIQYKVDKIEKNNARLIQR 140
K K++ALE+ + L Q K + + + E + + +++ +
Sbjct 790 K---------KSEALESIKQKLTKQEEEKKILKQDFETLSQETKIQHEELNNRIQTTVTE 840
Query 141 TSKDEKISINLDGDQATIVNTVGEGTDTV--VQTFFNELERNSKTEI-------KNTSIN 191
K + L + +T+ + + + +D++ ++ F + + K I K
Sbjct 841 LQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQ 900
Query 192 FSSIIDNTIINKYFLDLIKIDAKKYKVIDVIKLKLNKFN------SNVSEELELEDVDIT 245
++NT+ K +L K K+ + +KL+LN N ++ E E+ +
Sbjct 901 LQVQMENTL--KEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQ 958
Query 246 DELNSDPDKQKDELDKEDIKSALISGSSLLASNLFKVLSNKGYFISSIAWLVLEKTGEKR 305
+N KQ E K+ I++ + G +A L NK + E EK
Sbjct 959 GNINE--LKQSSEQKKKQIEA--LQGELKIAVLQKTELENK--LQQQLTQAAQELAAEKE 1012
Query 306 KI 307
KI
Sbjct 1013 KI 1014
Score = 23.9 bits (50), Expect = 0.78
Identities = 30/151 (20%), Positives = 64/151 (42%), Gaps = 15/151 (10%)
Query 88 TLPKADALETTLENLKSQLSNKDFIVDKLKNGNYEIQYKVDKIEKNNARLIQRTSKDEKI 147
T K + LE + Q+ +KD K++N +Q K N L+++ +D
Sbjct 500 TTAKLREAQNDLEQVLRQIGDKD---QKIQNLEALLQK-----SKENISLLEKEREDLYA 551
Query 148 SINLDGDQATIVNTVGEGTDTVVQTFFNELERNSKTEIKNTSINFSSIIDNTIINKYFLD 207
I + ++N + E T+ + E+ +KN S + +N + ++
Sbjct 552 KIQAGEGETAVLNQLQEKNHTLQEQVTQLTEK-----LKNQSESHKQAQEN-LHDQVQEQ 605
Query 208 LIKIDAKKYKVIDVIKLKLNKFNSNVSEELE 238
+ A + +V+ ++ +N+ NS ++E E
Sbjct 606 KAHLRAAQDRVLS-LETSVNELNSQLNESKE 635
Score = 21.6 bits (44), Expect = 4.1
Identities = 44/209 (21%), Positives = 83/209 (40%), Gaps = 27/209 (13%)
Query 74 ASKENFQKVTATNFTLPKADALETTLENLKS----QLSNKDFIVDKLKNGNYEIQYKVDK 129
A ENF + KA L T + ++KS + S ++ K+ E+ +
Sbjct 147 AQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATV 206
Query 130 IEKNNARLIQRTSKDEKISINLDGDQATIVNTVGEGTDTVVQTFFNELERNS---KTEIK 186
I+ L+QR ++ + + Q T++ E ER S K E K
Sbjct 207 IQDLKTELLQRPGIEDVAVLKKELVQ----------VQTLMDNMTLERERESEKLKDECK 256
Query 187 NTSINFSSIIDNTIINKYFLDLIKIDAKKYKVIDVIKLKLNKFNSNVSEELELEDVDITD 246
++S I++ +L AK + + V +L K S+V+ EL ++ +T+
Sbjct 257 KLQSQYAS--SEATISQLRSEL----AKGPQEVAVYVQELQKLKSSVN-ELTQKNQTLTE 309
Query 247 EL---NSDPDKQKDELDKEDIKSALISGS 272
L D K +++ ++E + I +
Sbjct 310 NLLKKEQDYTKLEEKHNEESVSKKNIQAT 338
Score = 20.4 bits (41), Expect = 9.2
Identities = 9/35 (26%), Positives = 19/35 (54%), Gaps = 0/35 (0%)
Query 325 ESKGFFEINSATQDYKKNRTTWKSNQRKMIEFAFQ 359
E+K +I + ++ + W+S+QR++ E Q
Sbjct 1236 EAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQ 1270
>Q8NCX0 Coiled-coil domain-containing protein 150 [Homo sapiens]
Length=1101
Score = 22.7 bits (47), Expect = 1.8
Identities = 50/258 (19%), Positives = 94/258 (36%), Gaps = 49/258 (19%)
Query 87 FTLPKADALETTLENLKSQL----SNKD-------FIVDKLK--NGNYEIQYKVDKIEKN 133
F + + LE+ +++LK + + KD F+ D+L + K+ +E
Sbjct 99 FLVNRMCRLESLMQSLKMNIFRLQTEKDLNPQKTAFLKDRLNAIQEEHSKDLKLLHLEVM 158
Query 134 NARLIQRTSKDEKISINLDGDQATIVNTVGEGTDTVVQTFFNELERNSKTEIKNTSINFS 193
N R R K+E+ + + T + T EL KT + ++
Sbjct 159 NLRQQLRAVKEEEDKAQDEVQRLTATLKIASQTKKNAAIIEEEL----KTTKRKMNLKIQ 214
Query 194 SIIDNTIINKYFLDLIKIDAKKYKVIDVIKLKLNKFNSNVSEE-----------LELED- 241
+ KY + ++ K + LK+ + S V E + L D
Sbjct 215 ELRRQLAQEKYLRESLE------KSASAMLLKIQEMGSTVEVERKQVHILQQNCIALRDS 268
Query 242 VDITDELNSDPDKQKDELD------------KEDIKSALISGSSLLASNLFKVLSNKGYF 289
+ EL + K+K+EL+ ++D+ S L+ + L + K Y
Sbjct 269 IQSAQELLAQEQKKKEELEIATSQLKSDLTSRDDLISKLVEENKNLQISFNKEHEENAYL 328
Query 290 ISSIAWLVLEKTGEKRKI 307
S I + L + EK ++
Sbjct 329 RSEI--MSLHEASEKAQV 344
Lambda K H a alpha
0.315 0.133 0.358 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 12556159
Database: 019f72833dddd60d302b508054c3560e.SwissProt.fasta
Posted date: May 9, 2024 3:56 AM
Number of letters in database: 39,991
Number of sequences in database: 10
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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