BLASTP 2.12.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: 5deba8ba3ef81c6643ac4010c13c8abe.SwissProt.fasta
           18 sequences; 9,015 total letters



Query= ACIAD2279

Length=353
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

P0AAP2 Probable diguanylate cyclase DgcC [Escherichia coli O6:H1 ...  167     9e-52
P0AAP1 Probable diguanylate cyclase DgcC [Escherichia coli (strai...  167     9e-52
P75908 Probable diguanylate cyclase DgcT [Escherichia coli (strai...  102     3e-27
P54595 Uncharacterized protein YhcK [Bacillus subtilis (strain 168)]  99.4    1e-26
Q9I310 Uncharacterized signaling protein PA1727 [Pseudomonas aeru...  100     3e-26
Q73RG3 Diguanylate cyclase A [Treponema denticola (strain ATCC 35...  93.6    2e-24
Q9HT84 Diguanylate cyclase DgcP [Pseudomonas aeruginosa (strain A...  93.6    6e-24
A0A0H2ZJS2 Diguanylate cyclase DgcP [Pseudomonas aeruginosa (stra...  92.0    2e-23
B8GZM2 Diguanylate cyclase [Caulobacter vibrioides (strain NA1000...  90.1    5e-23
Q9A5I5 Diguanylate cyclase [Caulobacter vibrioides (strain ATCC 1...  90.1    5e-23
Q3Z1N3 Diguanylate cyclase DosC [Shigella sonnei (strain Ss046)]      90.1    5e-23
Q320T0 Diguanylate cyclase DosC [Shigella boydii serotype 4 (stra...  90.1    5e-23
P0AA90 Diguanylate cyclase DosC [Escherichia coli O157:H7]            90.1    5e-23
P0AA89 Diguanylate cyclase DosC [Escherichia coli (strain K12)]       90.1    5e-23
Q8XAZ4 Probable diguanylate cyclase DgcF [Escherichia coli O157:H7]   86.7    3e-22
P76147 Probable diguanylate cyclase DgcF [Escherichia coli (strai...  86.7    3e-22
Q55434 Phytochrome-like protein cph2 [Synechocystis sp. (strain P...  88.2    5e-22
P77302 Diguanylate cyclase DgcM [Escherichia coli (strain K12)]       85.1    2e-21


>P0AAP2 Probable diguanylate cyclase DgcC [Escherichia coli O6:H1 
(strain CFT073 / ATCC 700928 / UPEC)]
Length=371

 Score = 167 bits (423),  Expect = 9e-52
 Identities = 101/330 (31%), Positives = 165/330 (50%), Gaps = 1/330 (0%)

Query  19   RYVFRIFVMRQIGTILCFFSIFSVLYYLNYHEIIYVLLALNAFVWPIAAYLYAKNKKDGV  78
            R+  R+ + R +G    F  I S L         +++L   AFVWP  A+  A    D +
Sbjct  36   RFARRVRLPRAVGLAGMFLPIASTLVSHPPPGWWWLVLVGWAFVWPHLAWQIASRAVDPL  95

Query  79   RTTNISLIVDAALGGMWVAIMKISPLPSLIMVAILVSDRFAAGGWQILRPSLIAMLGIFL  138
                 +L  DA L GMWV +M ++ LPS  M+ I+  +   AGG ++    L+ M+   L
Sbjct  96   SREIYNLKTDAVLAGMWVGVMGVNVLPSTAMLMIMCLNLMGAGGPRLFVAGLVLMVVSCL  155

Query  139  IFWSFTGFQVNLSFNEMMVWSSLPLATIYLISLSILTRKLAVQLIQKNREFERIALMDPR  198
            +    TG  V+ +   +  W SLP+  IY +    ++ + A +L +  R  + ++  D  
Sbjct  156  VTLELTGITVSFNSAPLEWWLSLPIIVIYPLLFGWVSYQTATKLAEHKRRLQVMSTRDGM  215

Query  199  LHIPNRRLFEQRLSSIFMQTQRNASSAHLILLDVDHFKKINDTYGHEAGDYFLAEMSSIL  258
              + NRR +E  L + F   +R+   A L+++D+DHFK INDT+GH+ GD  +  ++  L
Sbjct  216  TGVYNRRHWETMLRNEFDNCRRHNRDATLLIIDIDHFKSINDTWGHDVGDEAIVALTRQL  275

Query  259  RELIGPKDTPARFGGDELAIIVVDQSNEEIILLARRIKNSIQQIRLQSDPEFSTTVSIGI  318
            +  +   D   RFGGDE A+I+     E  I    R+   +  +RL + P+ +  +S+G+
Sbjct  276  QITLRGSDVIGRFGGDEFAVIMSGTPAESAITAMLRVHEGLNTLRLPNTPQVTLRISVGV  335

Query  319  ASAE-TVDTVSAWFALADKALYQVKRNGRN  347
            A     +     W   AD ALY+ K+ GRN
Sbjct  336  APLNPQMSHYREWLKSADLALYKAKKAGRN  365


>P0AAP1 Probable diguanylate cyclase DgcC [Escherichia coli (strain 
K12)]
Length=371

 Score = 167 bits (423),  Expect = 9e-52
 Identities = 101/330 (31%), Positives = 165/330 (50%), Gaps = 1/330 (0%)

Query  19   RYVFRIFVMRQIGTILCFFSIFSVLYYLNYHEIIYVLLALNAFVWPIAAYLYAKNKKDGV  78
            R+  R+ + R +G    F  I S L         +++L   AFVWP  A+  A    D +
Sbjct  36   RFARRVRLPRAVGLAGMFLPIASTLVSHPPPGWWWLVLVGWAFVWPHLAWQIASRAVDPL  95

Query  79   RTTNISLIVDAALGGMWVAIMKISPLPSLIMVAILVSDRFAAGGWQILRPSLIAMLGIFL  138
                 +L  DA L GMWV +M ++ LPS  M+ I+  +   AGG ++    L+ M+   L
Sbjct  96   SREIYNLKTDAVLAGMWVGVMGVNVLPSTAMLMIMCLNLMGAGGPRLFVAGLVLMVVSCL  155

Query  139  IFWSFTGFQVNLSFNEMMVWSSLPLATIYLISLSILTRKLAVQLIQKNREFERIALMDPR  198
            +    TG  V+ +   +  W SLP+  IY +    ++ + A +L +  R  + ++  D  
Sbjct  156  VTLELTGITVSFNSAPLEWWLSLPIIVIYPLLFGWVSYQTATKLAEHKRRLQVMSTRDGM  215

Query  199  LHIPNRRLFEQRLSSIFMQTQRNASSAHLILLDVDHFKKINDTYGHEAGDYFLAEMSSIL  258
              + NRR +E  L + F   +R+   A L+++D+DHFK INDT+GH+ GD  +  ++  L
Sbjct  216  TGVYNRRHWETMLRNEFDNCRRHNRDATLLIIDIDHFKSINDTWGHDVGDEAIVALTRQL  275

Query  259  RELIGPKDTPARFGGDELAIIVVDQSNEEIILLARRIKNSIQQIRLQSDPEFSTTVSIGI  318
            +  +   D   RFGGDE A+I+     E  I    R+   +  +RL + P+ +  +S+G+
Sbjct  276  QITLRGSDVIGRFGGDEFAVIMSGTPAESAITAMLRVHEGLNTLRLPNTPQVTLRISVGV  335

Query  319  ASAE-TVDTVSAWFALADKALYQVKRNGRN  347
            A     +     W   AD ALY+ K+ GRN
Sbjct  336  APLNPQMSHYREWLKSADLALYKAKKAGRN  365


>P75908 Probable diguanylate cyclase DgcT [Escherichia coli (strain 
K12)]
Length=452

 Score = 102 bits (254),  Expect = 3e-27
 Identities = 96/339 (28%), Positives = 158/339 (47%), Gaps = 48/339 (14%)

Query  43   LYYLNYHEIIYVLLALNAFVWPIAAYLYAKNKKDGVRTTNISLIVDAALGGMWVAIMKIS  102
            +YYL + ++   +L   A V  ++     +N      T  ISL      GG  VA +  S
Sbjct  114  IYYL-FRQMSLCILIFLALVNKVSENTKQRNLFSKKMTLCISLFF--VFGGPIVAHILSS  170

Query  103  PLPSL-IMVAILVSDRFAAGGWQILRPSLIAMLGIFLIFWSFTGFQVNLSFNEMM--VWS  159
               S  + +A L ++     G  + + S + ++    IF   T   VNL FN +   +W+
Sbjct  171  HYESYNLHIAELTNEN----GQVVWKASYVTIM----IFMWLTLLSVNLYFNGLRYDIWN  222

Query  160  SLPL----ATIYLISLSILTR----------------KLAVQLI------QKNREFERIA  193
             + +    A +Y ISL  ++R                KL V +I         R  + IA
Sbjct  223  GVTVIAFCAVLYNISLLFMSRYSVSTWYISRTIEVVSKLTVMVIFMCHIFSALRVTKNIA  282

Query  194  LMDPRLHIPNRRLFEQRLSSIFMQTQRNASSAHLILLDVDHFKKINDTYGHEAGDYFLAE  253
              DP  +I NR  F   L+      Q+      ++++D+DHFKK+NDT+GH  GD  +  
Sbjct  283  HRDPLTNIFNRNYFFNELTVQSASAQKTPYC--VMIMDIDHFKKVNDTWGHPVGDQVIKT  340

Query  254  MSSILRELIGPKDTPARFGGDELAIIVVDQSNEEIILLARRIKNSIQQIRLQSDPEFS--  311
            + +I+ + I P D  AR GG+E  +++ D   E    LA RI+ +++++    +PE++  
Sbjct  341  VVNIIGKSIRPDDLLARVGGEEFGVLLTDIDTERAKALAERIRENVERL-TGDNPEYAIP  399

Query  312  --TTVSIG-IASAETVDTVSAWFALADKALYQVKRNGRN  347
               T+SIG + + E     +  + LAD ALY+ K  GRN
Sbjct  400  QKVTISIGAVVTQENALNPNEIYRLADNALYEAKETGRN  438


>P54595 Uncharacterized protein YhcK [Bacillus subtilis (strain 
168)]
Length=359

 Score = 99.4 bits (246),  Expect = 1e-26
 Identities = 81/259 (31%), Positives = 132/259 (51%), Gaps = 21/259 (8%)

Query  96   VAIMKISPLPSLIMVAILVSDRFAAGGWQILRPSLIAMLGIFLIFWSFTGFQVNLSFNEM  155
            V I+ I+ +PSLI     VS R      Q+     + ++   LI +SF  F ++L   E+
Sbjct  106  VIIICIAAIPSLI-----VSRRKKV---QLKHAFYLLIITNSLISFSFY-FLIDLHSYEL  156

Query  156  MVWSSLPLATIYLISLSILTRKLAVQLIQKNREFERIALMDPRLHIPNRRLFEQRLSSIF  215
             ++  +      ++SL I+  +    L+ K  +F+  A  D    + NRR FE+   +++
Sbjct  157  HLYFWIISIAGGMLSLYIIDHETNAHLLFKQYKFQ--AHFDFLTGVYNRRKFEETTKALY  214

Query  216  MQTQRNASSAH----LILLDVDHFKKINDTYGHEAGDYFLAEMSSILRELIGPKDTPARF  271
             Q    A + H    LI +D+DHFK IND YGH  GD  L E+   L++ I   D  AR 
Sbjct  215  QQA---ADTPHFQFALIYMDIDHFKTINDQYGHHEGDQVLKELGLRLKQTIRNTDPAARI  271

Query  272  GGDELAIIVVDQSNEEIILLARRIKNSIQQ--IRLQSDPEFSTTVSIGIAS-AETVDTVS  328
            GG+E A+++ + S ++   +A RI++++    I L +  E S T+S+G A      +   
Sbjct  272  GGEEFAVLLPNCSLDKAARIAERIRSTVSDAPIVLTNGDELSVTISLGAAHYPNNTEQPG  331

Query  329  AWFALADKALYQVKRNGRN  347
            +   LAD+ LY+ K  GRN
Sbjct  332  SLPILADQMLYKAKETGRN  350


>Q9I310 Uncharacterized signaling protein PA1727 [Pseudomonas 
aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 
14847 / LMG 12228 / 1C / PRS 101 / PAO1)]
Length=685

 Score = 100 bits (249),  Expect = 3e-26
 Identities = 62/180 (34%), Positives = 88/180 (49%), Gaps = 1/180 (1%)

Query  171  LSILTRKLAVQLIQKNREFERIALMDPRLHIPNRRLFEQRLSSIFMQTQRNASSAHLILL  230
            L   T  LA  L + NRE  ++AL D    +PNR L + RL     Q  R+     ++ +
Sbjct  241  LEARTSVLATSLARANRELIQLALHDNLTKLPNRMLLDDRLEQAIQQAIRDDRRFAVLFM  300

Query  231  DVDHFKKINDTYGHEAGDYFLAEMSSILRELIGPKDTPARFGGDELAIIVVDQSNEEIIL  290
            D+D FK +ND YGH  GD  L E++  +R  +  +DT AR GGDE  +++  +   +   
Sbjct  301  DLDGFKAVNDAYGHHLGDLLLIEVAERIRANVRAQDTIARLGGDEFVLLIEAREPADAAT  360

Query  291  LARRIKNSIQQIRLQSDPEFSTTVSIGIA-SAETVDTVSAWFALADKALYQVKRNGRNGF  349
            LA ++   I Q    S  E   + SIGIA       T       AD A+Y  K  GRNG+
Sbjct  361  LAEKLVKRISQPYQISRHEVRISASIGIALYPGDGQTRHELMINADAAMYHAKDQGRNGY  420


 Score = 18.9 bits (37),  Expect = 5.5
 Identities = 10/25 (40%), Positives = 16/25 (64%), Gaps = 0/25 (0%)

Query  156  MVWSSLPLATIYLISLSILTRKLAV  180
            M+  SLP+   Y + L++L+  LAV
Sbjct  63   MLAFSLPIPLGYDLGLTLLSLLLAV  87


>Q73RG3 Diguanylate cyclase A [Treponema denticola (strain ATCC 
35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104)]
Length=371

 Score = 93.6 bits (231),  Expect = 2e-24
 Identities = 46/123 (37%), Positives = 79/123 (64%), Gaps = 2/123 (2%)

Query  227  LILLDVDHFKKINDTYGHEAGDYFLAEMSSILRELIGPKDTPARFGGDELAIIVVDQSNE  286
            ++++D+D FK INDTYGH AGD  L E++ I++      DT AR+GG+E  +++ + S  
Sbjct  237  ILMIDIDFFKNINDTYGHAAGDIVLEEVAKIIKSCTRNADTAARYGGEEFIVMLNNTSAS  296

Query  287  EIILLARRIKNSIQQIRLQSD-PEFSTTVSIGIASAE-TVDTVSAWFALADKALYQVKRN  344
              + +A RI+ S+++  +  D  + + T+SIG++S    +++  +    ADKALY+ K+N
Sbjct  297  AAMAVAERIRKSVEEKSIMYDGKKINVTISIGVSSYNFDLESAKSIVERADKALYESKQN  356

Query  345  GRN  347
            GRN
Sbjct  357  GRN  359


>Q9HT84 Diguanylate cyclase DgcP [Pseudomonas aeruginosa (strain 
ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 
/ 1C / PRS 101 / PAO1)]
Length=671

 Score = 93.6 bits (231),  Expect = 6e-24
 Identities = 58/157 (37%), Positives = 84/157 (54%), Gaps = 3/157 (2%)

Query  193  ALMDPRLHIPNRRLFEQRLSSIFMQTQRNASSAHLILLDVDHFKKINDTYGHEAGDYFLA  252
            AL DP   +PNR    +RL     +  R+     L +LD+DHFK+IND +GH AGD  L 
Sbjct  511  ALTDPLTGLPNRAALSERLEQEVARRHRDGGDLLLAVLDIDHFKRINDDFGHLAGDKVLK  570

Query  253  EMSSILRELIGPKDTPARFGGDELAIIVVDQSNEEIILLARRIKNSIQ--QIRLQSDPEF  310
             ++  LR+ +   D  ARFGG+E  +++   S E    L  R++ +I       + +P  
Sbjct  571  IIAGELRKRLRQADFIARFGGEEFVVLLPATSLEAGRQLLERLRAAIAACPFHFKGEP-L  629

Query  311  STTVSIGIASAETVDTVSAWFALADKALYQVKRNGRN  347
            S T S GI + E  +   A F  AD+ALY+ KR GR+
Sbjct  630  SITCSAGITAFEGNEAGEAVFERADQALYRAKRAGRD  666


>A0A0H2ZJS2 Diguanylate cyclase DgcP [Pseudomonas aeruginosa (strain 
UCBPP-PA14)]
Length=671

 Score = 92.0 bits (227),  Expect = 2e-23
 Identities = 57/157 (36%), Positives = 83/157 (53%), Gaps = 3/157 (2%)

Query  193  ALMDPRLHIPNRRLFEQRLSSIFMQTQRNASSAHLILLDVDHFKKINDTYGHEAGDYFLA  252
            AL DP   +PNR    +RL     +  R+     L +LD+DHFK+IND +GH AGD  L 
Sbjct  511  ALTDPLTGLPNRAALSERLEQEVARRHRDGGDLLLAVLDIDHFKRINDDFGHLAGDKVLK  570

Query  253  EMSSILRELIGPKDTPARFGGDELAIIVVDQSNEEIILLARRIKNSIQ--QIRLQSDPEF  310
             ++  LR+ +   D  ARFGG+E  +++   S E    L  R++ +I       + +P  
Sbjct  571  IIAGELRKRLRQADFIARFGGEEFVVLLPATSLEAGRQLLERLRAAIAACPFHFKGEP-L  629

Query  311  STTVSIGIASAETVDTVSAWFALADKALYQVKRNGRN  347
            S T S GI + E  +     F  AD+ALY+ KR GR+
Sbjct  630  SITCSAGITAFEGNEAGEVVFERADQALYRAKRAGRD  666


>B8GZM2 Diguanylate cyclase [Caulobacter vibrioides (strain NA1000 
/ CB15N)]
Length=454

 Score = 90.1 bits (222),  Expect = 5e-23
 Identities = 55/179 (31%), Positives = 89/179 (50%), Gaps = 5/179 (3%)

Query  174  LTRKLAVQLIQKNREFE-RIALMDPRLHIPNRRLFEQRLSSIFMQTQRNASSAHLILLDV  232
            + RK     ++ N +    +A+ D    + NRR    +L S+  +          +L+D+
Sbjct  269  IQRKRYTDYLRNNLDHSLELAVTDQLTGLHNRRYMTGQLDSLVKRATLGGDPVSALLIDI  328

Query  233  DHFKKINDTYGHEAGDYFLAEMSSILRELIGPKDTPARFGGDELAIIVVDQSNEEIILLA  292
            D FKKINDT+GH+ GD  L E +  L   +   D P R+GG+E  +I+ D +  + + +A
Sbjct  329  DFFKKINDTFGHDIGDEVLREFALRLASNVRAIDLPCRYGGEEFVVIMPDTALADALRIA  388

Query  293  RRIKNSIQQIRL---QSDPEFSTTVSIGI-ASAETVDTVSAWFALADKALYQVKRNGRN  347
             RI+  +              + T+SIG+ A+A   DT  A    AD+ +YQ K +GRN
Sbjct  389  ERIRMHVSGSPFTVAHGREMLNVTISIGVSATAGEGDTPEALLKRADEGVYQAKASGRN  447


>Q9A5I5 Diguanylate cyclase [Caulobacter vibrioides (strain ATCC 
19089 / CB15)]
Length=454

 Score = 90.1 bits (222),  Expect = 5e-23
 Identities = 55/179 (31%), Positives = 89/179 (50%), Gaps = 5/179 (3%)

Query  174  LTRKLAVQLIQKNREFE-RIALMDPRLHIPNRRLFEQRLSSIFMQTQRNASSAHLILLDV  232
            + RK     ++ N +    +A+ D    + NRR    +L S+  +          +L+D+
Sbjct  269  IQRKRYTDYLRNNLDHSLELAVTDQLTGLHNRRYMTGQLDSLVKRATLGGDPVSALLIDI  328

Query  233  DHFKKINDTYGHEAGDYFLAEMSSILRELIGPKDTPARFGGDELAIIVVDQSNEEIILLA  292
            D FKKINDT+GH+ GD  L E +  L   +   D P R+GG+E  +I+ D +  + + +A
Sbjct  329  DFFKKINDTFGHDIGDEVLREFALRLASNVRAIDLPCRYGGEEFVVIMPDTALADALRIA  388

Query  293  RRIKNSIQQIRL---QSDPEFSTTVSIGI-ASAETVDTVSAWFALADKALYQVKRNGRN  347
             RI+  +              + T+SIG+ A+A   DT  A    AD+ +YQ K +GRN
Sbjct  389  ERIRMHVSGSPFTVAHGREMLNVTISIGVSATAGEGDTPEALLKRADEGVYQAKASGRN  447


>Q3Z1N3 Diguanylate cyclase DosC [Shigella sonnei (strain Ss046)]
Length=460

 Score = 90.1 bits (222),  Expect = 5e-23
 Identities = 55/184 (30%), Positives = 96/184 (52%), Gaps = 7/184 (4%)

Query  176  RKLAVQLIQKNRE-FERIALMDPRLHIPNRRLFEQRLSSIFMQ----TQRNASSAHLILL  230
            R    Q+I   RE FE ++  +  + +  + L  + L +IF +      R  +   ++++
Sbjct  273  RNTVSQIITLLRELFEEVSRHEVGMDVLTKLLNRRFLPTIFKREIAHANRTGTPLSVLII  332

Query  231  DVDHFKKINDTYGHEAGDYFLAEMSSILRELIGPKDTPARFGGDELAIIVVDQSNEEIIL  290
            DVD FK+INDT+GH  GD  L ++S    + +   D   R+GGDE  I++ + S  E + 
Sbjct  333  DVDKFKEINDTWGHNTGDEILRKVSQAFYDNVHSSDYVFRYGGDEFIIVLTEASENETLR  392

Query  291  LARRIKNSIQQIRLQ--SDPEFSTTVSIGIASAETVDTVSAWFALADKALYQVKRNGRNG  348
             A RI++ +++ +L+  +  + + ++SIG A             +AD+ALY  KR GRN 
Sbjct  393  TAERIRSRVEKTKLKAANGEDIALSLSIGAAMFNGHPDYERLIQIADEALYIAKRRGRNR  452

Query  349  FHLY  352
              L+
Sbjct  453  VELW  456


>Q320T0 Diguanylate cyclase DosC [Shigella boydii serotype 4 (strain 
Sb227)]
Length=460

 Score = 90.1 bits (222),  Expect = 5e-23
 Identities = 55/184 (30%), Positives = 96/184 (52%), Gaps = 7/184 (4%)

Query  176  RKLAVQLIQKNRE-FERIALMDPRLHIPNRRLFEQRLSSIFMQ----TQRNASSAHLILL  230
            R    Q+I   RE FE ++  +  + +  + L  + L +IF +      R  +   ++++
Sbjct  273  RNTVSQIITLLRELFEEVSRHEVGMDVLTKLLNRRFLPTIFKREIAHANRTGTPLSVLII  332

Query  231  DVDHFKKINDTYGHEAGDYFLAEMSSILRELIGPKDTPARFGGDELAIIVVDQSNEEIIL  290
            DVD FK+INDT+GH  GD  L ++S    + +   D   R+GGDE  I++ + S  E + 
Sbjct  333  DVDKFKEINDTWGHNTGDEILRKVSQAFYDNVRSSDYVFRYGGDEFIIVLTEASENETLR  392

Query  291  LARRIKNSIQQIRLQ--SDPEFSTTVSIGIASAETVDTVSAWFALADKALYQVKRNGRNG  348
             A RI++ +++ +L+  +  + + ++SIG A             +AD+ALY  KR GRN 
Sbjct  393  TAERIRSRVEKTKLKAANGEDIALSLSIGAAMFNGHPDYERLIQIADEALYIAKRRGRNR  452

Query  349  FHLY  352
              L+
Sbjct  453  VELW  456


>P0AA90 Diguanylate cyclase DosC [Escherichia coli O157:H7]
Length=460

 Score = 90.1 bits (222),  Expect = 5e-23
 Identities = 55/184 (30%), Positives = 96/184 (52%), Gaps = 7/184 (4%)

Query  176  RKLAVQLIQKNRE-FERIALMDPRLHIPNRRLFEQRLSSIFMQ----TQRNASSAHLILL  230
            R    Q+I   RE FE ++  +  + +  + L  + L +IF +      R  +   ++++
Sbjct  273  RNTVSQIITLLRELFEEVSRHEVGMDVLTKLLNRRFLPTIFKREIAHANRTGTPLSVLII  332

Query  231  DVDHFKKINDTYGHEAGDYFLAEMSSILRELIGPKDTPARFGGDELAIIVVDQSNEEIIL  290
            DVD FK+INDT+GH  GD  L ++S    + +   D   R+GGDE  I++ + S  E + 
Sbjct  333  DVDKFKEINDTWGHNTGDEILRKVSQAFYDNVRSSDYVFRYGGDEFIIVLTEASENETLR  392

Query  291  LARRIKNSIQQIRLQ--SDPEFSTTVSIGIASAETVDTVSAWFALADKALYQVKRNGRNG  348
             A RI++ +++ +L+  +  + + ++SIG A             +AD+ALY  KR GRN 
Sbjct  393  TAERIRSRVEKTKLKAANGEDIALSLSIGAAMFNGHPDYERLIQIADEALYIAKRRGRNR  452

Query  349  FHLY  352
              L+
Sbjct  453  VELW  456


>P0AA89 Diguanylate cyclase DosC [Escherichia coli (strain K12)]
Length=460

 Score = 90.1 bits (222),  Expect = 5e-23
 Identities = 55/184 (30%), Positives = 96/184 (52%), Gaps = 7/184 (4%)

Query  176  RKLAVQLIQKNRE-FERIALMDPRLHIPNRRLFEQRLSSIFMQ----TQRNASSAHLILL  230
            R    Q+I   RE FE ++  +  + +  + L  + L +IF +      R  +   ++++
Sbjct  273  RNTVSQIITLLRELFEEVSRHEVGMDVLTKLLNRRFLPTIFKREIAHANRTGTPLSVLII  332

Query  231  DVDHFKKINDTYGHEAGDYFLAEMSSILRELIGPKDTPARFGGDELAIIVVDQSNEEIIL  290
            DVD FK+INDT+GH  GD  L ++S    + +   D   R+GGDE  I++ + S  E + 
Sbjct  333  DVDKFKEINDTWGHNTGDEILRKVSQAFYDNVRSSDYVFRYGGDEFIIVLTEASENETLR  392

Query  291  LARRIKNSIQQIRLQ--SDPEFSTTVSIGIASAETVDTVSAWFALADKALYQVKRNGRNG  348
             A RI++ +++ +L+  +  + + ++SIG A             +AD+ALY  KR GRN 
Sbjct  393  TAERIRSRVEKTKLKAANGEDIALSLSIGAAMFNGHPDYERLIQIADEALYIAKRRGRNR  452

Query  349  FHLY  352
              L+
Sbjct  453  VELW  456


>Q8XAZ4 Probable diguanylate cyclase DgcF [Escherichia coli O157:H7]
Length=315

 Score = 86.7 bits (213),  Expect = 3e-22
 Identities = 75/276 (27%), Positives = 128/276 (46%), Gaps = 28/276 (10%)

Query  83   ISLIVDAALGGMWVAIMKISPLPSLIMVAILVSDRFAAGGWQILRPSLIAMLGIFLIFWS  142
            +S+I    +GG   A     PLP+LI  A+  + +        L   +   + I L+  S
Sbjct  45   VSVIASVVIGG---AGSLAFPLPALIWCAVRYTPQVTC-----LLTFVTGAVEIVLVANS  96

Query  143  FTGFQVNLSFNEMMVWSS-LPLATI----YLISLSILTRKLAVQLIQKNREFERIALMDP  197
                 V   F+   ++S+ L +AT+     ++S S+      ++ +    +F+ +  +  
Sbjct  97   VIDISVGSPFSIPQMFSARLGIATMAICPIMVSFSVAAINSLMKQVALRADFDFLTQVYS  156

Query  198  RLHIPNRRLFEQRLSSIFMQTQRNASSAHLILLDVDHFKKINDTYGHEAGDYFLAEMSSI  257
            R       L+E   S    QTQ       ++LLD+D+FK IND YGHE GD  L+  +  
Sbjct  157  R-----SGLYEALKSPSLKQTQHLT----VMLLDIDYFKSINDNYGHECGDKVLSVFARH  207

Query  258  LRELIGPKDTPARFGGDELAIIVVDQSNEEIILLARRIKNSIQ-QIRLQSDPEFSTTVSI  316
            +++++G K   AR GG+E A+ V   +  + +L+A +I+  ++ Q           TVSI
Sbjct  208  IQKIVGDKGLVARMGGEEFAVAVPSVNPVDGLLMAEKIRKGVELQPFTWQQKTLYLTVSI  267

Query  317  GIASAET-----VDTVSAWFALADKALYQVKRNGRN  347
            G+ S         D  +     AD  LY+ K++GRN
Sbjct  268  GVGSGRASYRTLTDDFNKLMVEADTCLYRSKKDGRN  303


>P76147 Probable diguanylate cyclase DgcF [Escherichia coli (strain 
K12)]
Length=315

 Score = 86.7 bits (213),  Expect = 3e-22
 Identities = 75/276 (27%), Positives = 128/276 (46%), Gaps = 28/276 (10%)

Query  83   ISLIVDAALGGMWVAIMKISPLPSLIMVAILVSDRFAAGGWQILRPSLIAMLGIFLIFWS  142
            +S+I    +GG   A     PLP+LI  A+  + +        L   +   + I L+  S
Sbjct  45   VSVIASVVIGG---AGSLAFPLPALIWCAVRYTPQVTC-----LLTFVTGAVEIVLVANS  96

Query  143  FTGFQVNLSFNEMMVWSS-LPLATI----YLISLSILTRKLAVQLIQKNREFERIALMDP  197
                 V   F+   ++S+ L +AT+     ++S S+      ++ +    +F+ +  +  
Sbjct  97   VIDISVGSPFSIPQMFSARLGIATMAICPIMVSFSVAAINSLMKQVALRADFDFLTQVYS  156

Query  198  RLHIPNRRLFEQRLSSIFMQTQRNASSAHLILLDVDHFKKINDTYGHEAGDYFLAEMSSI  257
            R       L+E   S    QTQ       ++LLD+D+FK IND YGHE GD  L+  +  
Sbjct  157  R-----SGLYEALKSPSLKQTQHLT----VMLLDIDYFKSINDNYGHECGDKVLSVFARH  207

Query  258  LRELIGPKDTPARFGGDELAIIVVDQSNEEIILLARRIKNSIQ-QIRLQSDPEFSTTVSI  316
            +++++G K   AR GG+E A+ V   +  + +L+A +I+  ++ Q           TVSI
Sbjct  208  IQKIVGDKGLVARMGGEEFAVAVPSVNPVDGLLMAEKIRKGVELQPFTWQQKTLYLTVSI  267

Query  317  GIASAET-----VDTVSAWFALADKALYQVKRNGRN  347
            G+ S         D  +     AD  LY+ K++GRN
Sbjct  268  GVGSGRASYLTLTDDFNKLMVEADTCLYRSKKDGRN  303


>Q55434 Phytochrome-like protein cph2 [Synechocystis sp. (strain 
PCC 6803 / Kazusa)]
Length=1276

 Score = 88.2 bits (217),  Expect = 5e-22
 Identities = 61/189 (32%), Positives = 97/189 (51%), Gaps = 5/189 (3%)

Query  169   ISLSILTRKLAVQLIQKNREFERIALMDPRLHIPNRRLFEQRLSSIFMQTQRNASSAHLI  228
             ++++I   +L  QL   N   ++I+ +D    + NR LF+  L   + + QR      L+
Sbjct  1076  VAIAIHQGELYEQLETANIRLQQISSLDALTQVGNRYLFDSTLEREWQRLQRIREPLALL  1135

Query  229   LLDVDHFKKINDTYGHEAGDYFLAEMSSILRELI-GPKDTPARFGGDELAIIVVDQSNEE  287
             L DVD FK  ND YGH AGD  L +++  + ++   P D  AR+GG+E AII+ + S E 
Sbjct  1136  LCDVDFFKGFNDNYGHPAGDRCLKKIADAMAKVAKRPTDLVARYGGEEFAIILSETSLEG  1195

Query  288   IILLARRIKNSIQQIRLQSDPEFS--TTVSIGIA--SAETVDTVSAWFALADKALYQVKR  343
              I +   ++  +  + +      +   T+SIGIA  + E     +A    AD ALY+ K 
Sbjct  1196  AINVTEALQVEVANLAIPHTVSGTGHVTLSIGIAVYTPERHINPNALVKAADLALYEAKA  1255

Query  344   NGRNGFHLY  352
              GRN +  Y
Sbjct  1256  KGRNQWLAY  1264


 Score = 70.9 bits (172),  Expect = 2e-16
 Identities = 49/186 (26%), Positives = 95/186 (51%), Gaps = 14/186 (8%)

Query  174  LTRKLAVQLIQKNREFERIALMDPRLHIPNRRLFEQRLSSIFMQTQRNASSAHLILLDVD  233
            +T++   +LI +   +      DP   +PN  +F ++L+   +          ++++ +D
Sbjct  418  ITQQFVTRLITQQTAY------DPLTQLPNWIIFNRQLTLALLDALYEGKMVGVLVIAMD  471

Query  234  HFKKINDTYGHEAGDYFLAEMSSILRELIGP----KDTPARFGGDELAIIVVDQS-NEEI  288
             FK+IN+++GH+ GD  L E++  L + + P        +R+ GD   I++   S N+E+
Sbjct  472  RFKRINESFGHKTGDGLLQEVADRLNQKLSPLAAYSPLLSRWHGDGFTILLTQISDNQEM  531

Query  289  ILLARRIKNSIQQ-IRLQSDPEFSTTVSIGIASAE-TVDTVSAWFALADKALYQVKRNGR  346
            I L  R+ ++ Q+   LQ  P +  T S+GI++A    +T  +    A+ AL + K  G+
Sbjct  532  IPLCERLLSTFQEPFFLQGQPIY-LTASMGISTAPYDGETAESLLKFAEIALTRAKCQGK  590

Query  347  NGFHLY  352
            N +  Y
Sbjct  591  NTYQFY  596


>P77302 Diguanylate cyclase DgcM [Escherichia coli (strain K12)]
Length=410

 Score = 85.1 bits (209),  Expect = 2e-21
 Identities = 53/160 (33%), Positives = 77/160 (48%), Gaps = 2/160 (1%)

Query  188  EFERIALMDPRLHIPNRRLFEQRLSSIFMQTQRNASSAHLILLDVDHFKKINDTYGHEAG  247
            + E  A  D    + NRR F        MQ    A    L+L+D D FK IND YGH  G
Sbjct  248  QLEHAAHHDAMTGLLNRRQFYHITEPGQMQHLAIAQDYSLLLIDTDRFKHINDLYGHSKG  307

Query  248  DYFLAEMSSILRELIGPKDTPARFGGDELAIIVVDQSNEEIILLARRIKNSIQQIRLQSD  307
            D  L  ++  L       D   R+GG+E  +++     +  + LA  I+ S+ ++ +   
Sbjct  308  DEVLCALARTLESCARKGDLVFRWGGEEFVLLLPRTPLDTALSLAETIRVSVAKVSISGL  367

Query  308  PEFSTTVSIGIASAETVDTVSAWFALADKALYQVKRNGRN  347
            P F  TVSIG+A  E  +++   F   D ALY+ K +GRN
Sbjct  368  PRF--TVSIGVAHHEGNESIDELFKRVDDALYRAKNDGRN  405



Lambda      K        H        a         alpha
   0.329    0.141    0.418    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 2445294


  Database: 5deba8ba3ef81c6643ac4010c13c8abe.SwissProt.fasta
    Posted date:  May 29, 2024  2:44 PM
  Number of letters in database: 9,015
  Number of sequences in database:  18



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40