Comparative Genomics

ACIAD2333 / SwissProt Alignments

BLASTP 2.12.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: 34c245779e6ad397eca9594afec25093.SwissProt.fasta
           18 sequences; 3,105 total letters



Query= ACIAD2333

Length=155
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

B0FXI7 HTH-type transcriptional repressor IacR [Pseudomonas putida]   125     6e-41
O31564 Uncharacterized HTH-type transcriptional regulator YfiV [B...  53.9    3e-13
A1JNY1 Transcriptional regulator SlyA [Yersinia enterocolitica se...  47.8    4e-11
Q9S3W0 Transcriptional regulator SlyA [Yersinia enterocolitica]       47.8    4e-11
A7GLZ1 HTH-type transcriptional regulator Hpr [Bacillus cytotoxic...  45.8    3e-10
A4IKT9 HTH-type transcriptional regulator Hpr [Geobacillus thermo...  45.1    7e-10
A8GDX5 Transcriptional regulator SlyA [Serratia proteamaculans (s...  44.3    7e-10
Q2NT07 Transcriptional regulator SlyA [Sodalis glossinidius (stra...  44.3    7e-10
Q5L293 HTH-type transcriptional regulator Hpr [Geobacillus kausto...  44.7    9e-10
Q6HMB8 HTH-type transcriptional regulator Hpr [Bacillus thuringie...  43.5    2e-09
Q63EV6 HTH-type transcriptional regulator Hpr [Bacillus cereus (s...  43.5    2e-09
Q813W6 HTH-type transcriptional regulator Hpr [Bacillus cereus (s...  43.5    2e-09
B9IT66 HTH-type transcriptional regulator Hpr [Bacillus cereus (s...  43.5    2e-09
B7HZH8 HTH-type transcriptional regulator Hpr [Bacillus cereus (s...  43.5    2e-09
C5D6L6 HTH-type transcriptional regulator Hpr [Geobacillus sp. (s...  43.5    2e-09
P11065 DNA-binding transcriptional repressor ScoC [Bacillus subti...  43.1    3e-09
P69989 Transcriptional regulator SlyA [Yersinia pseudotuberculosi...  40.8    1e-08
Q04I02 Transcriptional regulator AdcR [Streptococcus pneumoniae s...  35.8    8e-07


>B0FXI7 HTH-type transcriptional repressor IacR [Pseudomonas putida]
Length=167

 Score = 125 bits (314),  Expect = 6e-41
 Identities = 58/152 (38%), Positives = 99/152 (65%), Gaps = 0/152 (0%)

Query  3    KKYSRFLPSEKSFNIDNFPYYWVTQVHSQYVHNIDNVLKRYGLDNSRRRILLALNIKQNA  62
            K +S   P+   F  ++FP+YW+ +VH +Y  N++ +LK+  LD  R R+L  LN    +
Sbjct  15   KGHSHHDPASDEFRKEDFPFYWLARVHGRYTQNMERLLKKIDLDVPRWRVLWILNENGES  74

Query  63   SVSELSEMIISKMSTTTKIVYRLKDEGFVNTYSCENDARITRVNLTEQGKEMIHKINSLT  122
            S+SE+S   I+K+ST TKIVYR+K++G V+T     D R+T+V +TE G + I ++  +T
Sbjct  75   SISEISTHAIAKLSTITKIVYRMKEDGLVDTAPSPEDGRVTQVRITEVGLQNIERMQEVT  134

Query  123  GAVLEQSFEGLTPLQIEKMIDGLKIIFKNLSS  154
              + ++SF+GLT  Q++++   L+++F NL +
Sbjct  135  RELFQRSFKGLTEAQVQRLNRMLEVVFHNLET  166


>O31564 Uncharacterized HTH-type transcriptional regulator YfiV 
[Bacillus subtilis (strain 168)]
Length=160

 Score = 53.9 bits (128),  Expect = 3e-13
 Identities = 37/133 (28%), Positives = 67/133 (50%), Gaps = 2/133 (2%)

Query  24   WVTQVHSQYVHNIDNVLKRYGLDNS--RRRILLALNIKQNASVSELSEMIISKMSTTTKI  81
            WV  +       + +V +   LD S  + ++L+ LN      VS+++E + + +S TT +
Sbjct  24   WVLYMKVLTSAGLGDVSEWMKLDMSMPQMKVLMLLNNHGTLKVSDIAEKMGASLSNTTGL  83

Query  82   VYRLKDEGFVNTYSCENDARITRVNLTEQGKEMIHKINSLTGAVLEQSFEGLTPLQIEKM  141
            + RL+  GFV     E D R   V LTE  K++   +       L++S E L+P + + +
Sbjct  84   LDRLEKSGFVKRSHSEEDRRSVVVQLTENAKKIFRGLYEKGHLKLKRSLELLSPEEKQAV  143

Query  142  IDGLKIIFKNLSS  154
             +GL I+ + L +
Sbjct  144  YEGLSILSRALEN  156


>A1JNY1 Transcriptional regulator SlyA [Yersinia enterocolitica 
serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)]
Length=143

 Score = 47.8 bits (112),  Expect = 4e-11
 Identities = 31/121 (26%), Positives = 62/121 (51%), Gaps = 20/121 (17%)

Query  25   VTQVHSQYVHNIDNVLKRYGLDNSRRRILLALNIKQNASVSELSEMIISKMSTTTKIVYR  84
            +TQ H   +HNI+    R   + S+ ++  A+ I+Q + V  L +               
Sbjct  29   LTQTHWVTLHNIN----RLPPEQSQIQLAKAIGIEQPSLVRTLDQ---------------  69

Query  85   LKDEGFVNTYSCENDARITRVNLTEQGKEMIHKINSLTGAVLEQSFEGLTPLQIEKMIDG  144
            L+++G +  ++C ND R  R+ LTEQ   +I +++ +  +  ++   G++P +IE ++ G
Sbjct  70   LEEKGLITRHTCANDRRAKRIKLTEQSSPIIEQVDGVICSTRKEILGGISPDEIE-LLSG  128

Query  145  L  145
            L
Sbjct  129  L  129


 Score = 17.7 bits (34),  Expect = 1.3
 Identities = 8/23 (35%), Positives = 12/23 (52%), Gaps = 0/23 (0%)

Query  99   DARITRVNLTEQGKEMIHKINSL  121
            D R+  + LT+     +H IN L
Sbjct  21   DHRLKPLELTQTHWVTLHNINRL  43


>Q9S3W0 Transcriptional regulator SlyA [Yersinia enterocolitica]
Length=143

 Score = 47.8 bits (112),  Expect = 4e-11
 Identities = 31/121 (26%), Positives = 62/121 (51%), Gaps = 20/121 (17%)

Query  25   VTQVHSQYVHNIDNVLKRYGLDNSRRRILLALNIKQNASVSELSEMIISKMSTTTKIVYR  84
            +TQ H   +HNI+    R   + S+ ++  A+ I+Q + V  L +               
Sbjct  29   LTQTHWVTLHNIN----RLPPEQSQIQLAKAIGIEQPSLVRTLDQ---------------  69

Query  85   LKDEGFVNTYSCENDARITRVNLTEQGKEMIHKINSLTGAVLEQSFEGLTPLQIEKMIDG  144
            L+++G +  ++C ND R  R+ LTEQ   +I +++ +  +  ++   G++P +IE ++ G
Sbjct  70   LEEKGLITRHTCANDRRAKRIKLTEQSSPIIEQVDGVICSTRKEILGGISPDEIE-LLSG  128

Query  145  L  145
            L
Sbjct  129  L  129


 Score = 17.7 bits (34),  Expect = 1.3
 Identities = 8/23 (35%), Positives = 12/23 (52%), Gaps = 0/23 (0%)

Query  99   DARITRVNLTEQGKEMIHKINSL  121
            D R+  + LT+     +H IN L
Sbjct  21   DHRLKPLELTQTHWVTLHNINRL  43


>A7GLZ1 HTH-type transcriptional regulator Hpr [Bacillus cytotoxicus 
(strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98)]
Length=185

 Score = 45.8 bits (107),  Expect = 3e-10
 Identities = 31/109 (28%), Positives = 58/109 (53%), Gaps = 9/109 (8%)

Query  40   LKRYGLDNSRRRILLALNIKQNASVSELSEMIISKMSTTTKIVYRLKDEGFVNTYSCEND  99
            +K Y L+ +   IL      + AS+SE+++  +  +ST      +L++ G++     E+D
Sbjct  39   IKPYDLNINEHHILSIAYHLEGASISEIAKFGVMHVSTAFNFSKKLEERGYLVFSKKEDD  98

Query  100  ARITRVNLTEQGKEMIHKI--------NSL-TGAVLEQSFEGLTPLQIE  139
             R T + +TE+G+E++ K+        NS+  GA+  ++F G  P  IE
Sbjct  99   KRNTYIEITEKGEELLLKLMEEYNPENNSVFNGALALRNFYGKFPENIE  147


>A4IKT9 HTH-type transcriptional regulator Hpr [Geobacillus thermodenitrificans 
(strain NG80-2)]
Length=200

 Score = 45.1 bits (105),  Expect = 7e-10
 Identities = 25/98 (26%), Positives = 51/98 (52%), Gaps = 0/98 (0%)

Query  40   LKRYGLDNSRRRILLALNIKQNASVSELSEMIISKMSTTTKIVYRLKDEGFVNTYSCEND  99
            +K + L+ +   IL      + AS+SE+++  +  +ST      +L+++G ++    ++D
Sbjct  39   IKPFNLNINEHHILWIAYHFKGASISEIAKFGVMHVSTAFNFSKKLEEKGLLSFSKKQDD  98

Query  100  ARITRVNLTEQGKEMIHKINSLTGAVLEQSFEGLTPLQ  137
             R T + LTE+G+E++ K+           F G  PL+
Sbjct  99   KRNTYIELTEKGEEVLMKLMETYDPTRNAVFNGALPLR  136


>A8GDX5 Transcriptional regulator SlyA [Serratia proteamaculans 
(strain 568)]
Length=144

 Score = 44.3 bits (103),  Expect = 7e-10
 Identities = 25/119 (21%), Positives = 63/119 (53%), Gaps = 1/119 (1%)

Query  36   IDNVLKRYGLDNSRRRILLALN-IKQNASVSELSEMIISKMSTTTKIVYRLKDEGFVNTY  94
            ID+ LK   L  +    L ++N +    S  +L++ I  +  +  + + +L+++G +  +
Sbjct  20   IDHRLKPLALTQTHWVTLHSINRLPPEQSQIQLAKAIGIEQPSLVRTLDQLEEKGLITRH  79

Query  95   SCENDARITRVNLTEQGKEMIHKINSLTGAVLEQSFEGLTPLQIEKMIDGLKIIFKNLS  153
            +C ND R  R+ LTE    +I +++S+  +   +   G+T  +++ ++  +  + +N++
Sbjct  80   TCANDRRAKRIKLTEAADPIIREVDSVISSTRGEILSGITTDEVQLLVGLIGKLEQNIT  138


>Q2NT07 Transcriptional regulator SlyA [Sodalis glossinidius (strain 
morsitans)]
Length=144

 Score = 44.3 bits (103),  Expect = 7e-10
 Identities = 28/128 (22%), Positives = 63/128 (49%), Gaps = 19/128 (15%)

Query  25   VTQVHSQYVHNIDNVLKRYGLDNSRRRILLALNIKQNASVSELSEMIISKMSTTTKIVYR  84
            +TQ H   +HNI  +      + S+ ++  A+ I+Q + V  L +               
Sbjct  29   LTQTHWITLHNICQLPP----EQSQIQLAKAIGIEQPSLVRTLDQ---------------  69

Query  85   LKDEGFVNTYSCENDARITRVNLTEQGKEMIHKINSLTGAVLEQSFEGLTPLQIEKMIDG  144
            L+++G +  ++C ND R  R+ LTE  + +I ++N++  +   +   G++  +I+ + + 
Sbjct  70   LEEKGLITRHTCANDRRAKRIKLTESAEPIIKEVNNVIDSTRNEILNGISQEEIQLLSNM  129

Query  145  LKIIFKNL  152
            +  + KN+
Sbjct  130  IAKLEKNI  137


>Q5L293 HTH-type transcriptional regulator Hpr [Geobacillus kaustophilus 
(strain HTA426)]
Length=201

 Score = 44.7 bits (104),  Expect = 9e-10
 Identities = 25/98 (26%), Positives = 51/98 (52%), Gaps = 0/98 (0%)

Query  40   LKRYGLDNSRRRILLALNIKQNASVSELSEMIISKMSTTTKIVYRLKDEGFVNTYSCEND  99
            +K + L+ +   IL      + AS+SE+++  +  +ST      +L+++G ++    ++D
Sbjct  39   IKPFDLNINEHHILWIAYHFKGASISEIAKFGVMHVSTAFNFSKKLEEKGLLSFSKKQDD  98

Query  100  ARITRVNLTEQGKEMIHKINSLTGAVLEQSFEGLTPLQ  137
             R T + LTE+G+E++ K+           F G  PL+
Sbjct  99   KRNTYIELTEKGEEVLMKLMETYDPTKNAVFNGALPLR  136


>Q6HMB8 HTH-type transcriptional regulator Hpr [Bacillus thuringiensis 
subsp. konkukian (strain 97-27)]
Length=185

 Score = 43.5 bits (101),  Expect = 2e-09
 Identities = 29/109 (27%), Positives = 58/109 (53%), Gaps = 9/109 (8%)

Query  40   LKRYGLDNSRRRILLALNIKQNASVSELSEMIISKMSTTTKIVYRLKDEGFVNTYSCEND  99
            +K Y L+ +   IL      + AS+SE+++  +  +ST      +L++ G++     E+D
Sbjct  39   IKPYDLNINEHHILTIAYHLKGASISEIAKFGVMHVSTAFNFSKKLEERGYLVFSKKEDD  98

Query  100  ARITRVNLTEQGKEMIHKI--------NSL-TGAVLEQSFEGLTPLQIE  139
             R T + +T++G+E++ ++        NS+  GA+  ++F G  P  IE
Sbjct  99   KRNTYIEITDKGEELLLRLMEEYDPENNSVFNGALALRNFYGKFPENIE  147


>Q63EV6 HTH-type transcriptional regulator Hpr [Bacillus cereus 
(strain ZK / E33L)]
Length=185

 Score = 43.5 bits (101),  Expect = 2e-09
 Identities = 29/109 (27%), Positives = 58/109 (53%), Gaps = 9/109 (8%)

Query  40   LKRYGLDNSRRRILLALNIKQNASVSELSEMIISKMSTTTKIVYRLKDEGFVNTYSCEND  99
            +K Y L+ +   IL      + AS+SE+++  +  +ST      +L++ G++     E+D
Sbjct  39   IKPYDLNINEHHILTIAYHLKGASISEIAKFGVMHVSTAFNFSKKLEERGYLVFSKKEDD  98

Query  100  ARITRVNLTEQGKEMIHKI--------NSL-TGAVLEQSFEGLTPLQIE  139
             R T + +T++G+E++ ++        NS+  GA+  ++F G  P  IE
Sbjct  99   KRNTYIEITDKGEELLLRLMEEYDPENNSVFNGALALRNFYGKFPENIE  147


>Q813W6 HTH-type transcriptional regulator Hpr [Bacillus cereus 
(strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 
15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)]
Length=185

 Score = 43.5 bits (101),  Expect = 2e-09
 Identities = 29/109 (27%), Positives = 58/109 (53%), Gaps = 9/109 (8%)

Query  40   LKRYGLDNSRRRILLALNIKQNASVSELSEMIISKMSTTTKIVYRLKDEGFVNTYSCEND  99
            +K Y L+ +   IL      + AS+SE+++  +  +ST      +L++ G++     E+D
Sbjct  39   IKPYDLNINEHHILTIAYHLKGASISEIAKFGVMHVSTAFNFSKKLEERGYLVFSKKEDD  98

Query  100  ARITRVNLTEQGKEMIHKI--------NSL-TGAVLEQSFEGLTPLQIE  139
             R T + +T++G+E++ ++        NS+  GA+  ++F G  P  IE
Sbjct  99   KRNTYIEITDKGEELLLRLMEEYDPENNSVFNGALALRNFYGKFPENIE  147


>B9IT66 HTH-type transcriptional regulator Hpr [Bacillus cereus 
(strain Q1)]
Length=185

 Score = 43.5 bits (101),  Expect = 2e-09
 Identities = 29/109 (27%), Positives = 58/109 (53%), Gaps = 9/109 (8%)

Query  40   LKRYGLDNSRRRILLALNIKQNASVSELSEMIISKMSTTTKIVYRLKDEGFVNTYSCEND  99
            +K Y L+ +   IL      + AS+SE+++  +  +ST      +L++ G++     E+D
Sbjct  39   IKPYDLNINEHHILTIAYHLKGASISEIAKFGVMHVSTAFNFSKKLEERGYLVFSKKEDD  98

Query  100  ARITRVNLTEQGKEMIHKI--------NSL-TGAVLEQSFEGLTPLQIE  139
             R T + +T++G+E++ ++        NS+  GA+  ++F G  P  IE
Sbjct  99   KRNTYIEITDKGEELLLRLMEEYDPENNSVFNGALALRNFYGKFPENIE  147


>B7HZH8 HTH-type transcriptional regulator Hpr [Bacillus cereus 
(strain AH187)]
Length=185

 Score = 43.5 bits (101),  Expect = 2e-09
 Identities = 29/109 (27%), Positives = 58/109 (53%), Gaps = 9/109 (8%)

Query  40   LKRYGLDNSRRRILLALNIKQNASVSELSEMIISKMSTTTKIVYRLKDEGFVNTYSCEND  99
            +K Y L+ +   IL      + AS+SE+++  +  +ST      +L++ G++     E+D
Sbjct  39   IKPYDLNINEHHILTIAYHLKGASISEIAKFGVMHVSTAFNFSKKLEERGYLVFSKKEDD  98

Query  100  ARITRVNLTEQGKEMIHKI--------NSL-TGAVLEQSFEGLTPLQIE  139
             R T + +T++G+E++ ++        NS+  GA+  ++F G  P  IE
Sbjct  99   KRNTYIEITDKGEELLLRLMEEYDPENNSVFNGALALRNFYGKFPENIE  147


>C5D6L6 HTH-type transcriptional regulator Hpr [Geobacillus sp. 
(strain WCH70)]
Length=201

 Score = 43.5 bits (101),  Expect = 2e-09
 Identities = 25/98 (26%), Positives = 50/98 (51%), Gaps = 0/98 (0%)

Query  40   LKRYGLDNSRRRILLALNIKQNASVSELSEMIISKMSTTTKIVYRLKDEGFVNTYSCEND  99
            +K + L+ +   IL      + AS+SE+++  +  +ST      +L++ G ++    ++D
Sbjct  39   IKPFDLNINEHHILWIAYHFKGASISEIAKFGVMHVSTAFNFSKKLEERGLLSFSKKQDD  98

Query  100  ARITRVNLTEQGKEMIHKINSLTGAVLEQSFEGLTPLQ  137
             R T + LTE+G+E++ K+           F G  PL+
Sbjct  99   KRNTYIELTEKGEEVLLKLMESYDPTQNAVFNGALPLR  136


>P11065 DNA-binding transcriptional repressor ScoC [Bacillus subtilis 
(strain 168)]
Length=203

 Score = 43.1 bits (100),  Expect = 3e-09
 Identities = 28/97 (29%), Positives = 45/97 (46%), Gaps = 0/97 (0%)

Query  40   LKRYGLDNSRRRILLALNIKQNASVSELSEMIISKMSTTTKIVYRLKDEGFVNTYSCEND  99
            LK Y L+ +   IL        AS+SE+++  +  +ST      +L++ G++      ND
Sbjct  39   LKPYDLNINEHHILWIAYQLNGASISEIAKFGVMHVSTAFNFSKKLEERGYLRFSKRLND  98

Query  100  ARITRVNLTEQGKEMIHKINSLTGAVLEQSFEGLTPL  136
             R T V LTE+G E+   +           F+G  PL
Sbjct  99   KRNTYVQLTEEGTEVFWSLLEEFDPTRNAVFKGSQPL  135


>P69989 Transcriptional regulator SlyA [Yersinia pseudotuberculosis 
serotype I (strain IP32953)]
Length=143

 Score = 40.8 bits (94),  Expect = 1e-08
 Identities = 26/118 (22%), Positives = 60/118 (51%), Gaps = 1/118 (1%)

Query  36   IDNVLKRYGLDNSRRRILLALN-IKQNASVSELSEMIISKMSTTTKIVYRLKDEGFVNTY  94
            ID+ LK   L  +    L  +N +    S  +L++ I  +  +  + + +L+++G +  +
Sbjct  20   IDHRLKPLELTQTHWVTLYNINRLPPEQSQIQLAKAIGIEQPSLVRTLDQLEEKGLITRH  79

Query  95   SCENDARITRVNLTEQGKEMIHKINSLTGAVLEQSFEGLTPLQIEKMIDGLKIIFKNL  152
            +C ND R  R+ LTEQ   +I +++ +  +  ++   G++  +I  +   +  + KN+
Sbjct  80   TCANDRRAKRIKLTEQSSPIIEQVDGVICSTRKEILGGISSDEIAVLSGLIDKLEKNI  137


>Q04I02 Transcriptional regulator AdcR [Streptococcus pneumoniae 
serotype 2 (strain D39 / NCTC 7466)]
Length=146

 Score = 35.8 bits (81),  Expect = 8e-07
 Identities = 29/114 (25%), Positives = 50/114 (44%), Gaps = 4/114 (4%)

Query  25   VTQVHSQYVHNIDNVLKRYGLDNSRRRILLALNIKQNASVSELSEMIISKMSTTTKIVYR  84
            + Q  +Q+   I +      L N++  IL+ L+ +++ + SEL+  +    +  TK +  
Sbjct  16   ILQAENQHEILIGHCTSEVALTNTQEHILMLLS-EESLTNSELARRLNVSQAAVTKAIKS  74

Query  85   LKDEGFVNTYSCENDARITRVNLTEQGK---EMIHKINSLTGAVLEQSFEGLTP  135
            L  EG + T     DAR+    LT+  +   E  H  +  T    EQ     TP
Sbjct  75   LVKEGMLETSKDSKDARVIFYQLTDLARPIAEEHHHHHEHTLLTYEQVATQFTP  128



Lambda      K        H        a         alpha
   0.322    0.135    0.380    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 292383


  Database: 34c245779e6ad397eca9594afec25093.SwissProt.fasta
    Posted date:  Jun 1, 2024  9:58 PM
  Number of letters in database: 3,105
  Number of sequences in database:  18



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40