BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: bea90d97f305f5bf8a3f87f5fb1a169d.SwissProt.fasta
11 sequences; 1,741 total letters
Query= ACIAD2353
Length=199
Score E
Sequences producing significant alignments: (Bits) Value
Q9ZKR8 6-carboxy-5,6,7,8-tetrahydropterin synthase [Helicobacter ... 154 3e-51
O25587 6-carboxy-5,6,7,8-tetrahydropterin synthase [Helicobacter ... 145 4e-48
O66626 6-carboxy-5,6,7,8-tetrahydropterin synthase [Aquifex aeoli... 55.1 1e-13
Q4UKI6 6-carboxy-5,6,7,8-tetrahydropterin synthase [Rickettsia fe... 51.2 2e-12
Q92J44 6-carboxy-5,6,7,8-tetrahydropterin synthase [Rickettsia co... 50.1 6e-12
Q68XI9 6-carboxy-5,6,7,8-tetrahydropterin synthase [Rickettsia ty... 49.3 1e-11
Q9ZDY5 6-carboxy-5,6,7,8-tetrahydropterin synthase [Rickettsia pr... 48.9 2e-11
O59602 Putative 6-carboxy-5,6,7,8-tetrahydropterin synthase [Pyro... 43.5 2e-09
Q58668 Putative 6-carboxy-5,6,7,8-tetrahydropterin synthase [Meth... 43.5 2e-09
O27296 Putative 6-carboxy-5,6,7,8-tetrahydropterin synthase [Meth... 39.3 6e-08
O31676 6-carboxy-5,6,7,8-tetrahydropterin synthase [Bacillus subt... 36.6 4e-07
>Q9ZKR8 6-carboxy-5,6,7,8-tetrahydropterin synthase [Helicobacter
pylori (strain J99 / ATCC 700824)]
Length=200
Score = 154 bits (388), Expect = 3e-51
Identities = 72/188 (38%), Positives = 121/188 (64%), Gaps = 3/188 (2%)
Query 1 MLIRKLFKFENAHIVRNCTSDRCKRSIHGHSYKVELLLKANRLDHGQMVYDFGLLKGVIK 60
M+IR+L+KF +H+VRNC+S +C ++IHGH+Y+VE+ ++ NRLD+ M DFGL++ ++
Sbjct 1 MVIRRLYKFCASHVVRNCSSLKCAQNIHGHNYEVEVFIETNRLDNANMALDFGLMQQEMQ 60
Query 61 ELFDSFDHAICFWQDDNPEYIQACKTFSARWISLPVSPSAEQFSRIFFFLAQQVLHSTIT 120
DSFDHA FW ++PE+ + + R++ + SAE ++ +F + ++L ++
Sbjct 61 TFIDSFDHAHHFWDKESPEFQRFIENHCVRYVKCSFNLSAESYALMFLYYLTKILQKSVF 120
Query 121 QNGEGDVEVYSVIVHETDTGYAQSFLEDIQNVQMGTLDLKD--IIFSDQVQLEWTDSQMY 178
N EG+++V SV VHET GYA+SFL+D++N +L + D + FS +Q W D +
Sbjct 121 SNNEGELKVSSVRVHETKNGYAESFLKDLENPHFKSL-VHDHCVSFSQGIQSLWHDKDFF 179
Query 179 EKLRQGDK 186
K+ +K
Sbjct 180 HKIISDEK 187
>O25587 6-carboxy-5,6,7,8-tetrahydropterin synthase [Helicobacter
pylori (strain ATCC 700392 / 26695)]
Length=200
Score = 145 bits (367), Expect = 4e-48
Identities = 69/188 (37%), Positives = 120/188 (64%), Gaps = 3/188 (2%)
Query 1 MLIRKLFKFENAHIVRNCTSDRCKRSIHGHSYKVELLLKANRLDHGQMVYDFGLLKGVIK 60
M+IR+L++F +H+VRNC+S +C ++IHGH+Y+VE+ ++ NRLD+ M DFGL++ ++
Sbjct 1 MVIRRLYQFCASHVVRNCSSLKCAQNIHGHNYEVEVFIETNRLDNANMALDFGLMQQEMQ 60
Query 61 ELFDSFDHAICFWQDDNPEYIQACKTFSARWISLPVSPSAEQFSRIFFFLAQQVLHSTIT 120
+SFDHA FW ++ E+ + + R++ + SAE ++ +F + ++L ++
Sbjct 61 VFIESFDHAHHFWDKESLEFQRFIENHCVRYVKCSFNLSAESYALMFLYYLTKILQKSVF 120
Query 121 QNGEGDVEVYSVIVHETDTGYAQSFLEDIQNVQMGTLDLKD--IIFSDQVQLEWTDSQMY 178
N EG+++V SV VHET GYA+SFL+D++N +L + D + FS +Q W D +
Sbjct 121 SNDEGELKVSSVRVHETKNGYAESFLKDLENPHFKSL-VHDHCVSFSQGIQNLWHDKDFF 179
Query 179 EKLRQGDK 186
K+ +K
Sbjct 180 NKIISDEK 187
>O66626 6-carboxy-5,6,7,8-tetrahydropterin synthase [Aquifex aeolicus
(strain VF5)]
Length=162
Score = 55.1 bits (131), Expect = 1e-13
Identities = 47/159 (30%), Positives = 78/159 (49%), Gaps = 23/159 (14%)
Query 3 IRKLFKFENAHIV--RNCTSDRCKR-----------SIHGHSYKVELLLKANRLDHGQMV 49
I K F+FE H V +N T R + ++HGHSY +E+ + ++ L MV
Sbjct 5 ISKTFRFEAGHRVWKQNLTYGRGAQFTKEKPVNKCVNLHGHSYVLEVTVGSDTLSEQDMV 64
Query 50 YDFGLLKGVIKELFDSFDHAICFWQDD--NPEYIQACKTFSARWISLPVS--PSAEQFSR 105
DF +K +K L + DH+ +D PE + + A I PV P+AE ++
Sbjct 65 MDFYHVKNALKGLIEEIDHSFIIDVNDPMYPELKDVAEKYGAMKI-FPVEFCPTAEALAK 123
Query 106 IFF-FLAQQVLHSTITQNGEGDVEVYSVIVHETDTGYAQ 143
F+ FL +++ + + G+V+V V++ ET T A+
Sbjct 124 FFYDFLKKRLEEAGLL----GEVKVVKVVLWETATSKAE 158
>Q4UKI6 6-carboxy-5,6,7,8-tetrahydropterin synthase [Rickettsia
felis (strain ATCC VR-1525 / URRWXCal2)]
Length=138
Score = 51.2 bits (121), Expect = 2e-12
Identities = 24/51 (47%), Positives = 34/51 (67%), Gaps = 1/51 (2%)
Query 27 IHGHSYKVELLLKANRLDHGQMVYDFGLLKGVIKELFD-SFDHAICFWQDD 76
+HGH Y +E+ + AN+ D MV DFGL+K V K+ D +FDH++ QDD
Sbjct 26 LHGHRYVLEIAIAANKTDKLGMVIDFGLIKDVAKKWIDENFDHSLILHQDD 76
>Q92J44 6-carboxy-5,6,7,8-tetrahydropterin synthase [Rickettsia
conorii (strain ATCC VR-613 / Malish 7)]
Length=138
Score = 50.1 bits (118), Expect = 6e-12
Identities = 23/51 (45%), Positives = 34/51 (67%), Gaps = 1/51 (2%)
Query 27 IHGHSYKVELLLKANRLDHGQMVYDFGLLKGVIKELFD-SFDHAICFWQDD 76
+HGH Y +E+ + AN+ D MV DFGL+K + K+ D +FDH++ QDD
Sbjct 26 LHGHRYVLEIAIAANKTDKLGMVIDFGLIKDLAKKWIDENFDHSLILHQDD 76
>Q68XI9 6-carboxy-5,6,7,8-tetrahydropterin synthase [Rickettsia
typhi (strain ATCC VR-144 / Wilmington)]
Length=138
Score = 49.3 bits (116), Expect = 1e-11
Identities = 23/51 (45%), Positives = 33/51 (65%), Gaps = 1/51 (2%)
Query 27 IHGHSYKVELLLKANRLDHGQMVYDFGLLKGVIKELFD-SFDHAICFWQDD 76
+HGH Y +E+ + AN+ D MV DFGL+K + K+ D +FDH + QDD
Sbjct 26 LHGHHYVLEITIAANKTDKLGMVIDFGLIKNLAKKWIDANFDHNLILHQDD 76
>Q9ZDY5 6-carboxy-5,6,7,8-tetrahydropterin synthase [Rickettsia
prowazekii (strain Madrid E)]
Length=138
Score = 48.9 bits (115), Expect = 2e-11
Identities = 23/51 (45%), Positives = 33/51 (65%), Gaps = 1/51 (2%)
Query 27 IHGHSYKVELLLKANRLDHGQMVYDFGLLKGVIKELFD-SFDHAICFWQDD 76
+HGH Y +E+ + AN+ D MV DFGL+K + K+ D +FDH + QDD
Sbjct 26 LHGHHYVLEITIAANKTDTLGMVIDFGLIKNLAKKWIDANFDHNLILHQDD 76
>O59602 Putative 6-carboxy-5,6,7,8-tetrahydropterin synthase [Pyrococcus
horikoshii (strain ATCC 700860 / DSM 12428 / JCM
9974 / NBRC 100139 / OT-3)]
Length=157
Score = 43.5 bits (101), Expect = 2e-09
Identities = 23/62 (37%), Positives = 40/62 (65%), Gaps = 5/62 (8%)
Query 4 RKLF---KFENAHIVRNCTSDRCKRSIHGHSYKVELLLKANRLDHGQMVYDFGLLKGVIK 60
RK++ +F+++H + +CKR IHGH+YKVE+ ++ + G M++DF L ++K
Sbjct 9 RKIYWTKEFDSSHFLELEYESKCKR-IHGHTYKVEVEIEGELNEEG-MIFDFTHLSEIVK 66
Query 61 EL 62
EL
Sbjct 67 EL 68
>Q58668 Putative 6-carboxy-5,6,7,8-tetrahydropterin synthase [Methanocaldococcus
jannaschii (strain ATCC 43067 / DSM 2661
/ JAL-1 / JCM 10045 / NBRC 100440)]
Length=163
Score = 43.5 bits (101), Expect = 2e-09
Identities = 23/63 (37%), Positives = 35/63 (56%), Gaps = 3/63 (5%)
Query 8 KFENAHIVRNCTSDRCKRSIHGHSYKVELLLKANRLDHGQMVYDFGLLKGVIKELFDSFD 67
+F +AHIV + IHGHSY V++ L R + V DF ++K ++KE+ D D
Sbjct 13 RFSSAHIVFGHPTCGV---IHGHSYYVDVKLYGERAGDFKFVCDFKIIKKIVKEICDELD 69
Query 68 HAI 70
H +
Sbjct 70 HKL 72
>O27296 Putative 6-carboxy-5,6,7,8-tetrahydropterin synthase [Methanothermobacter
thermautotrophicus (strain ATCC 29096 /
DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)]
Length=161
Score = 39.3 bits (90), Expect = 6e-08
Identities = 20/63 (32%), Positives = 33/63 (52%), Gaps = 3/63 (5%)
Query 8 KFENAHIVRNCTSDRCKRSIHGHSYKVELLLKANRLDHGQMVYDFGLLKGVIKELFDSFD 67
+F AH++ S C IHGHSY V++ ++ R V DF +K +++ + FD
Sbjct 16 RFSAAHMIPEHESCGC---IHGHSYIVDVKVEGKRSGKHGFVADFKDVKDIVRRICSEFD 72
Query 68 HAI 70
H +
Sbjct 73 HKL 75
>O31676 6-carboxy-5,6,7,8-tetrahydropterin synthase [Bacillus
subtilis (strain 168)]
Length=146
Score = 36.6 bits (83), Expect = 4e-07
Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 9/70 (13%)
Query 12 AHIVRNCTSDRCKRSIHGHSYKVELLLKANRLDHGQMVYDFGLLKGVIKELFDSFDHAIC 71
AH + ++ C R +HGH+Y V + + + LD + +F +LK K + ++DH +
Sbjct 26 AHFIPRESAGACSR-VHGHTYTVNITVAGDELDDSGFLVNFSVLK---KLVHGNYDHTLL 81
Query 72 -----FWQDD 76
F QDD
Sbjct 82 NDHEDFSQDD 91
Lambda K H a alpha
0.326 0.139 0.426 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 225555
Database: bea90d97f305f5bf8a3f87f5fb1a169d.SwissProt.fasta
Posted date: May 30, 2024 6:16 PM
Number of letters in database: 1,741
Number of sequences in database: 11
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
