BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 0691a3acaf6eba9280ba911bba910796.SwissProt.fasta
17 sequences; 10,761 total letters
Query= ACIAD2395
Length=880
Score E
Sequences producing significant alignments: (Bits) Value
Q9I2V5 Aconitate hydratase B [Pseudomonas aeruginosa (strain ATCC... 1321 0.0
Q8ZRS8 Aconitate hydratase B [Salmonella typhimurium (strain LT2 ... 1291 0.0
P36683 Aconitate hydratase B [Escherichia coli (strain K12)] 1286 0.0
P74582 Aconitate hydratase B [Synechocystis sp. (strain PCC 6803 ... 1060 0.0
P56418 Aconitate hydratase B [Helicobacter pylori (strain ATCC 70... 944 0.0
Q9ZL64 Aconitate hydratase B [Helicobacter pylori (strain J99 / A... 941 0.0
P81291 Isopropylmalate/citramalate isomerase large subunit [Metha... 128 1e-34
O28084 3-isopropylmalate dehydratase large subunit 2 [Archaeoglob... 127 3e-34
Q4JC09 3-isopropylmalate dehydratase large subunit [Sulfolobus ac... 124 2e-33
B2KBD7 3-isopropylmalate dehydratase large subunit [Elusimicrobiu... 124 2e-33
Q58409 Methanogen homoaconitase large subunit [Methanocaldococcus... 121 3e-32
Q9ZNE0 Homoaconitase large subunit [Thermus thermophilus (strain ... 117 4e-31
Q0QLE2 2,3-dimethylmalate dehydratase large subunit [Eubacterium ... 95.1 1e-23
Q92412 Homoaconitase, mitochondrial [Emericella nidulans (strain ... 96.3 2e-23
Q44427 3-isopropylmalate dehydratase large subunit [Actinoplanes ... 94.0 5e-23
P17279 3-isopropylmalate dehydratase [Mucor circinelloides f. lus... 87.8 8e-21
P55251 3-isopropylmalate dehydratase [Rhizomucor pusillus] 87.0 2e-20
>Q9I2V5 Aconitate hydratase B [Pseudomonas aeruginosa (strain
ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228
/ 1C / PRS 101 / PAO1)]
Length=869
Score = 1321 bits (3420), Expect = 0.0
Identities = 659/865 (76%), Positives = 738/865 (85%), Gaps = 6/865 (1%)
Query 1 VLEAYRQHVEERAALGVPPKPLDDAQTADLVELLKNPPAGEEAFLVDLLENRVPAGVDQA 60
+LEAYR+HVEERAA GV P+PL+ QTA LVELLKNPPAGEE FL+DL+ NRVP GVD+A
Sbjct 1 MLEAYRKHVEERAAQGVVPQPLNAEQTAGLVELLKNPPAGEEEFLLDLITNRVPPGVDEA 60
Query 61 AYVKAAFLAALAKGEATSPLVSKERAVYLLGTMLGGYNVAPLVELLEDADLGALAADALK 120
AYVKA FL+A+ KGEATSPL+ K+RA LLGTM GGYN+A LVELL+DA+L AA+ LK
Sbjct 61 AYVKAGFLSAIVKGEATSPLIDKQRAAELLGTMQGGYNIATLVELLDDAELANTAAEQLK 120
Query 121 KTLLVFDAFHDVADKAKAGNTNAKAVLQSWADAEWFTSRKDVPEEIKLTVFKVTGETNTD 180
TLL+FDAFHDVA++AK GN AK+VLQSWAD EWF ++ +VPE++ LTVFKV GETNTD
Sbjct 121 HTLLMFDAFHDVAERAKKGNAAAKSVLQSWADGEWFKAKPEVPEKLTLTVFKVPGETNTD 180
Query 181 DLSPAQDAWSRPDIPLHANAMLKNERDGINPEKPGEVGPLSQIKELIAKGNQVAYVGDVV 240
DLSPA DAWSRPDIPLHA AMLK RDGI P +PG VGPL QI+ + AKG VAYVGDVV
Sbjct 181 DLSPAPDAWSRPDIPLHALAMLKMARDGIEPVQPGSVGPLKQIEAVKAKGFPVAYVGDVV 240
Query 241 GTGSSRKSATNSVLWFFGDEIAHIPNKKDGGYCLGSKIAPIFFNTMEDAGALPVEIDVAN 300
GTGSSRKSATNSVLWFFGD+I +PNK+ GG+C G+KIAPIF+NTMEDAGALP+E D N
Sbjct 241 GTGSSRKSATNSVLWFFGDDIPFVPNKRAGGFCFGTKIAPIFYNTMEDAGALPIEFDCTN 300
Query 301 MNMGDEIVLKIDHAAAKVTAFKNGEQIAESELKTPVLLDEVRAGGRINLIVGRGLTTKAR 360
+ MGD V+ + KV +GE + ELKTPVLLDEVRAGGRI LIVGRGLT KAR
Sbjct 301 LAMGD--VIDVYPYEGKVVRHDSGEVVTTFELKTPVLLDEVRAGGRIPLIVGRGLTEKAR 358
Query 361 EALGLEPSTLFRTPVQPAATGKGFTLAQKMVGRACGLPEGQGVIPGTYCEPKMTTVGSQD 420
LGL S LFR P PA +GKGFTLAQKMVGRACGLPEGQGV PGTYCEPKMTTVGSQD
Sbjct 359 AELGLGASDLFRKPEAPADSGKGFTLAQKMVGRACGLPEGQGVRPGTYCEPKMTTVGSQD 418
Query 421 TTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPKPVDVQMQHTLPDFIMNRGGVSLRPG 480
TTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPKP+DV+ HTLPDFIM RGGVSLRPG
Sbjct 419 TTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPKPIDVKTHHTLPDFIMTRGGVSLRPG 478
Query 481 DGIIHSWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLVK 540
DGIIHSWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLV+
Sbjct 479 DGIIHSWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLVR 538
Query 541 FKGKMQPGITLRDLVHAIPYYAIKEGDLTVEKKGKKNIFSGRILEIDLTEMETDLTVEQA 600
FKGK+QPGITLRDLVHAIPYYAI++G LTVEKKGKKNIFSGRILEI E DLTVEQA
Sbjct 539 FKGKLQPGITLRDLVHAIPYYAIQQGLLTVEKKGKKNIFSGRILEI---EGLNDLTVEQA 595
Query 601 FELSDASAERSAAGCAITLSEEKVAEYLRSNITMLKWMISQGYGDARTMARRVENMEKWL 660
FELSDASAERSAAGC I L E+ +AEYL+SNIT+L+WMI +GYGD RT+ RR + ME WL
Sbjct 596 FELSDASAERSAAGCTIKLPEQAIAEYLKSNITLLRWMIGEGYGDPRTLERRAQAMEAWL 655
Query 661 ANPSLLKADADAEYTKVYEIDLADIKEPILCCPNDPDDAKLLSDVQGDKIDEVFIGSCMT 720
A P LL+AD DAEY V EIDLAD+KEP+LC PNDPDDA+LLS VQG KIDEVFIGSCMT
Sbjct 656 AKPELLEADKDAEYAAVIEIDLADVKEPVLCAPNDPDDARLLSSVQGRKIDEVFIGSCMT 715
Query 721 NIGHFRAAGQLLEKVPSGSLTTRLWLAPPTRMDEHQLMEEGFYNTYGRAGARTEMPGCSL 780
NIGHFRAAG+LL+KV G + TRLWLAPPT+MD HQL EEG+Y YG+AGAR EMPGCSL
Sbjct 716 NIGHFRAAGKLLDKV-KGGIPTRLWLAPPTKMDAHQLTEEGYYGIYGKAGARMEMPGCSL 774
Query 781 CMGNQARVAPNTTVVSTSTRNFPNRLGQGSNVYLASAELASVAAVLGKLPTPEEYQQYAA 840
CMGNQARV +TVVSTSTRNFPNRLG ++V+LASAELA+V+++LGKLPT EEY YA
Sbjct 775 CMGNQARVQTGSTVVSTSTRNFPNRLGDATDVFLASAELAAVSSILGKLPTVEEYMAYAK 834
Query 841 QIDSMSADIYKYLNFDKMGEYTNAA 865
IDSM+AD+Y+YL+FD++ E+ AA
Sbjct 835 DIDSMAADVYRYLSFDQIAEFREAA 859
>Q8ZRS8 Aconitate hydratase B [Salmonella typhimurium (strain
LT2 / SGSC1412 / ATCC 700720)]
Length=865
Score = 1291 bits (3340), Expect = 0.0
Identities = 645/868 (74%), Positives = 733/868 (84%), Gaps = 9/868 (1%)
Query 1 VLEAYRQHVEERAALGVPPKPLDDAQTADLVELLKNPPAGEEAFLVDLLENRVPAGVDQA 60
+LE YR+HV ERAA G+ PKPLD Q A LVELLK PP GEE FL+DLL NRVP GVD+A
Sbjct 1 MLEEYRKHVAERAAQGIVPKPLDATQMAALVELLKTPPVGEEEFLLDLLINRVPPGVDEA 60
Query 61 AYVKAAFLAALAKGEATSPLVSKERAVYLLGTMLGGYNVAPLVELLEDADLGALAADALK 120
AYVKA FLAA+AKG+ TSPLVS E+A+ LLGTM GGYN+ PL++ L+DA L +AA AL
Sbjct 61 AYVKAGFLAAVAKGDTTSPLVSPEKAIELLGTMQGGYNIHPLIDALDDAKLAPIAAKALS 120
Query 121 KTLLVFDAFHDVADKAKAGNTNAKAVLQSWADAEWFTSRKDVPEEIKLTVFKVTGETNTD 180
TLL+FD F+DV +KAKAGN AK V+QSWADAEWF SR + E+I +TVFKVTGETNTD
Sbjct 121 HTLLMFDNFYDVEEKAKAGNEYAKQVMQSWADAEWFLSRPPLAEKITVTVFKVTGETNTD 180
Query 181 DLSPAQDAWSRPDIPLHANAMLKNERDGINPEKPGEVGPLSQIKELIAKGNQVAYVGDVV 240
DLSPA DAWSRPDIPLHA AMLKN R+GI P++PG VGP+ QI+ L KG +AYVGDVV
Sbjct 181 DLSPAPDAWSRPDIPLHAQAMLKNAREGIEPDQPGVVGPIKQIEALQKKGYPLAYVGDVV 240
Query 241 GTGSSRKSATNSVLWFFGDEIAHIPNKKDGGYCLGSKIAPIFFNTMEDAGALPVEIDVAN 300
GTGSSRKSATNSVLWF GD+I ++PNK+ GG CLG KIAPIFFNTMEDAGALP+E+DV+N
Sbjct 241 GTGSSRKSATNSVLWFMGDDIPNVPNKRGGGLCLGGKIAPIFFNTMEDAGALPIEVDVSN 300
Query 301 MNMGDEIVLKIDHAAAKVTAFKNGEQIAESELKTPVLLDEVRAGGRINLIVGRGLTTKAR 360
+NMGD V+ + +V + GE +A ELKT VL+DEVRAGGRI LI+GRGLTTKAR
Sbjct 301 LNMGD--VIDVYPYKGEVRNHETGELLATFELKTDVLIDEVRAGGRIPLIIGRGLTTKAR 358
Query 361 EALGLEPSTLFRTPVQPAATGKGFTLAQKMVGRACGLPEGQGVIPGTYCEPKMTTVGSQD 420
EALGL S +FR A + +GF+LAQKMVGRACG+ +G+ PG YCEPKMT+VGSQD
Sbjct 359 EALGLPHSDVFRQAKDVAESSRGFSLAQKMVGRACGV---KGIRPGAYCEPKMTSVGSQD 415
Query 421 TTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPKPVDVQMQHTLPDFIMNRGGVSLRPG 480
TTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPKPVDV HTLPDFIMNRGGVSLRPG
Sbjct 416 TTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPKPVDVTTHHTLPDFIMNRGGVSLRPG 475
Query 481 DGIIHSWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLVK 540
DG+IHSWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLV+
Sbjct 476 DGVIHSWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLVR 535
Query 541 FKGKMQPGITLRDLVHAIPYYAIKEGDLTVEKKGKKNIFSGRILEIDLTEMETDLTVEQA 600
FKGKMQPGITLRDLVHAIP YAIK+G LTVEKKGKKNIFSGRILEI E DL VEQA
Sbjct 536 FKGKMQPGITLRDLVHAIPLYAIKQGLLTVEKKGKKNIFSGRILEI---EGLPDLKVEQA 592
Query 601 FELSDASAERSAAGCAITLSEEKVAEYLRSNITMLKWMISQGYGDARTMARRVENMEKWL 660
FEL+DASAERSAAGC I L++E + EYL SNI +LKWMI++GYGD RT+ RR++ MEKWL
Sbjct 593 FELTDASAERSAAGCTIKLNKEPIVEYLTSNIVLLKWMIAEGYGDRRTLERRIQGMEKWL 652
Query 661 ANPSLLKADADAEYTKVYEIDLADIKEPILCCPNDPDDAKLLSDVQGDKIDEVFIGSCMT 720
A+P LL+ADADAEY V +IDLADIKEPILC PNDPDDA+LLSDVQG+KIDEVFIGSCMT
Sbjct 653 ADPQLLEADADAEYAAVIDIDLADIKEPILCAPNDPDDARLLSDVQGEKIDEVFIGSCMT 712
Query 721 NIGHFRAAGQLLEKVPSGSLTTRLWLAPPTRMDEHQLMEEGFYNTYGRAGARTEMPGCSL 780
NIGHFRAAG+LL+ G L TRLW+APPTRMD QL EEG+Y+ +G++GAR E+PGCSL
Sbjct 713 NIGHFRAAGKLLDN-HKGQLPTRLWVAPPTRMDAAQLTEEGYYSVFGKSGARIEIPGCSL 771
Query 781 CMGNQARVAPNTTVVSTSTRNFPNRLGQGSNVYLASAELASVAAVLGKLPTPEEYQQYAA 840
CMGNQARVA TVVSTSTRNFPNRLG G+NV+LASAELA+VAA++GKLPTPEEYQ Y A
Sbjct 772 CMGNQARVADGATVVSTSTRNFPNRLGTGANVFLASAELAAVAALIGKLPTPEEYQTYVA 831
Query 841 QIDSMSADIYKYLNFDKMGEYTNAADQV 868
Q+D + D Y+YLNFD++ +YT AD V
Sbjct 832 QVDKTAVDTYRYLNFDQLSQYTEKADGV 859
>P36683 Aconitate hydratase B [Escherichia coli (strain K12)]
Length=865
Score = 1286 bits (3328), Expect = 0.0
Identities = 643/868 (74%), Positives = 733/868 (84%), Gaps = 9/868 (1%)
Query 1 VLEAYRQHVEERAALGVPPKPLDDAQTADLVELLKNPPAGEEAFLVDLLENRVPAGVDQA 60
+LE YR+HV ERAA G+ PKPLD Q A LVELLKNPPAGEE FL+DLL NRVP GVD+A
Sbjct 1 MLEEYRKHVAERAAEGIAPKPLDANQMAALVELLKNPPAGEEEFLLDLLTNRVPPGVDEA 60
Query 61 AYVKAAFLAALAKGEATSPLVSKERAVYLLGTMLGGYNVAPLVELLEDADLGALAADALK 120
AYVKA FLAA+AKGEA SPL++ E+A+ LLGTM GGYN+ PL++ L+DA L +AA AL
Sbjct 61 AYVKAGFLAAIAKGEAKSPLLTPEKAIELLGTMQGGYNIHPLIDALDDAKLAPIAAKALS 120
Query 121 KTLLVFDAFHDVADKAKAGNTNAKAVLQSWADAEWFTSRKDVPEEIKLTVFKVTGETNTD 180
TLL+FD F+DV +KAKAGN AK V+QSWADAEWF +R + E++ +TVFKVTGETNTD
Sbjct 121 HTLLMFDNFYDVEEKAKAGNEYAKQVMQSWADAEWFLNRPALAEKLTVTVFKVTGETNTD 180
Query 181 DLSPAQDAWSRPDIPLHANAMLKNERDGINPEKPGEVGPLSQIKELIAKGNQVAYVGDVV 240
DLSPA DAWSRPDIPLHA AMLKN R+GI P++PG VGP+ QI+ L KG +AYVGDVV
Sbjct 181 DLSPAPDAWSRPDIPLHALAMLKNAREGIEPDQPGVVGPIKQIEALQQKGFPLAYVGDVV 240
Query 241 GTGSSRKSATNSVLWFFGDEIAHIPNKKDGGYCLGSKIAPIFFNTMEDAGALPVEIDVAN 300
GTGSSRKSATNSVLWF GD+I H+PNK+ GG CLG KIAPIFFNTMEDAGALP+E+DV+N
Sbjct 241 GTGSSRKSATNSVLWFMGDDIPHVPNKRGGGLCLGGKIAPIFFNTMEDAGALPIEVDVSN 300
Query 301 MNMGDEIVLKIDHAAAKVTAFKNGEQIAESELKTPVLLDEVRAGGRINLIVGRGLTTKAR 360
+NMGD V+ + +V + GE +A ELKT VL+DEVRAGGRI LI+GRGLTTKAR
Sbjct 301 LNMGD--VIDVYPYKGEVRNHETGELLATFELKTDVLIDEVRAGGRIPLIIGRGLTTKAR 358
Query 361 EALGLEPSTLFRTPVQPAATGKGFTLAQKMVGRACGLPEGQGVIPGTYCEPKMTTVGSQD 420
EALGL S +FR A + +GF+LAQKMVGRACG+ +G+ PG YCEPKMT+VGSQD
Sbjct 359 EALGLPHSDVFRQAKDVAESDRGFSLAQKMVGRACGV---KGIRPGAYCEPKMTSVGSQD 415
Query 421 TTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPKPVDVQMQHTLPDFIMNRGGVSLRPG 480
TTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPKPVDV HTLPDFIMNRGGVSLRPG
Sbjct 416 TTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPKPVDVNTHHTLPDFIMNRGGVSLRPG 475
Query 481 DGIIHSWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLVK 540
DG+IHSWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLV+
Sbjct 476 DGVIHSWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLVR 535
Query 541 FKGKMQPGITLRDLVHAIPYYAIKEGDLTVEKKGKKNIFSGRILEIDLTEMETDLTVEQA 600
FKGKMQPGITLRDLVHAIP YAIK+G LTVEKKGKKNIFSGRILEI E DL VEQA
Sbjct 536 FKGKMQPGITLRDLVHAIPLYAIKQGLLTVEKKGKKNIFSGRILEI---EGLPDLKVEQA 592
Query 601 FELSDASAERSAAGCAITLSEEKVAEYLRSNITMLKWMISQGYGDARTMARRVENMEKWL 660
FEL+DASAERSAAGC I L++E + EYL SNI +LKWMI++GYGD RT+ RR++ MEKWL
Sbjct 593 FELTDASAERSAAGCTIKLNKEPIIEYLNSNIVLLKWMIAEGYGDRRTLERRIQGMEKWL 652
Query 661 ANPSLLKADADAEYTKVYEIDLADIKEPILCCPNDPDDAKLLSDVQGDKIDEVFIGSCMT 720
ANP LL+ADADAEY V +IDLADIKEPILC PNDPDDA+ LS VQG+KIDEVFIGSCMT
Sbjct 653 ANPELLEADADAEYAAVIDIDLADIKEPILCAPNDPDDARPLSAVQGEKIDEVFIGSCMT 712
Query 721 NIGHFRAAGQLLEKVPSGSLTTRLWLAPPTRMDEHQLMEEGFYNTYGRAGARTEMPGCSL 780
NIGHFRAAG+LL+ G L TRLW+APPTRMD QL EEG+Y+ +G++GAR E+PGCSL
Sbjct 713 NIGHFRAAGKLLD-AHKGQLPTRLWVAPPTRMDAAQLTEEGYYSVFGKSGARIEIPGCSL 771
Query 781 CMGNQARVAPNTTVVSTSTRNFPNRLGQGSNVYLASAELASVAAVLGKLPTPEEYQQYAA 840
CMGNQARVA TVVSTSTRNFPNRLG G+NV+LASAELA+VAA++GKLPTPEEYQ Y A
Sbjct 772 CMGNQARVADGATVVSTSTRNFPNRLGTGANVFLASAELAAVAALIGKLPTPEEYQTYVA 831
Query 841 QIDSMSADIYKYLNFDKMGEYTNAADQV 868
Q+D + D Y+YLNF+++ +YT AD V
Sbjct 832 QVDKTAVDTYRYLNFNQLSQYTEKADGV 859
>P74582 Aconitate hydratase B [Synechocystis sp. (strain PCC 6803
/ Kazusa)]
Length=868
Score = 1060 bits (2742), Expect = 0.0
Identities = 546/864 (63%), Positives = 664/864 (77%), Gaps = 25/864 (3%)
Query 1 VLEAYRQHVEERAALGVPPKPLDDAQTADLVELLKNPPAGEEAFLVDLLENRVPAGVDQA 60
+L+AYR+HV +R LG+PP PL+ QT +L ELLKNPP E+ L+ LL +RVP GVD+A
Sbjct 1 MLQAYRRHVADRQKLGIPPLPLNAQQTTELCELLKNPPEAEKEELMMLLRDRVPPGVDEA 60
Query 61 AYVKAAFLAALAKGEATSPLVSKERAVYLLGTMLGGYNVAPLVELLE--DADLGALAADA 118
AYVKA FL A+AKGE T PL+S + AV LLGTM+GGYNV L+ELL+ D ++ + AA A
Sbjct 61 AYVKAGFLTAIAKGEVTCPLISGQGAVDLLGTMIGGYNVQSLIELLKSKDTNIASAAATA 120
Query 119 LKKTLLVFDAFHDVADKAKAGNTNAKAVLQSWADAEWFTSRKDVPEEIKLTVFKVTGETN 178
L KTLLVFDAF+DV + N AK V+ +WA+ WF ++ +VPE I +TVFKV GETN
Sbjct 121 LSKTLLVFDAFNDVLHLSDT-NGYAKQVIDAWAEGAWFINKPEVPERITVTVFKVPGETN 179
Query 179 TDDLSPAQDAWSRPDIPLHANAMLKNERDGINPEKPGEVGPLSQIKELIAKGNQVAYVGD 238
TDDLSPA A +RPDIPLHA AML+ + P +G ++++K+ KG+ VAYVGD
Sbjct 180 TDDLSPAPHATTRPDIPLHALAMLE-------AKMPEGLGTIAELKQ---KGHPVAYVGD 229
Query 239 VVGTGSSRKSATNSVLWFFGDEIAHIPNKKDGGYCLGSKIAPIFFNTMEDAGALPVEIDV 298
VVGTGSSRKSA NSVLW G +I +PNK+ GGY LG KIAPIFFNT ED+GALP+E DV
Sbjct 230 VVGTGSSRKSAINSVLWHIGTDIPFVPNKRAGGYILGGKIAPIFFNTAEDSGALPIECDV 289
Query 299 ANMNMGDEIVLKIDHAAAKVTAFKNGEQIAESELKTPVLLDEVRAGGRINLIVGRGLTTK 358
+N GD V+ I K+T K GE I +LK +LDEVRAGGRI L++GR LT K
Sbjct 290 NQLNTGD--VITIYPREGKITN-KAGETITTFQLKPETILDEVRAGGRIPLLIGRALTDK 346
Query 359 AREALGLEPSTLFRTPVQPAATGKGFTLAQKMVGRACGLPEGQGVIPGTYCEPKMTTVGS 418
REALGL PS LF P PA TGKGFTLAQKMVG+ACG+ QG+ PGT CEP MTTVGS
Sbjct 347 TREALGLSPSPLFVRPTAPADTGKGFTLAQKMVGKACGV---QGIRPGTSCEPIMTTVGS 403
Query 419 QDTTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPKPVDVQMQHTLPDFIMNRGGVSLR 478
QDTTGPMTRDELK+LACLGF+ADL +Q+FCHTAAYPKPVD++ LPDF RGGV+LR
Sbjct 404 QDTTGPMTRDELKELACLGFNADLTLQTFCHTAAYPKPVDIKTHKDLPDFFSTRGGVALR 463
Query 479 PGDGIIHSWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVL 538
PGDGIIHSWLNRMLLPDTVGTGGDSHTRFP+GISFPAGSGLVAFAAA GVMPLDMPESVL
Sbjct 464 PGDGIIHSWLNRMLLPDTVGTGGDSHTRFPLGISFPAGSGLVAFAAALGVMPLDMPESVL 523
Query 539 VKFKGKMQPGITLRDLVHAIPYYAIKEGDLTVEKKGKKNIFSGRILEIDLTEMETDLTVE 598
VKF G++QPG+TLRD+V+AIP+ A+++G LTV K K N+F+GRI+E+ E DL VE
Sbjct 524 VKFTGELQPGVTLRDIVNAIPWVAMQQGKLTVGKGDKVNVFNGRIMEM---EGLPDLKVE 580
Query 599 QAFELSDASAERSAAGCAITLSEEKVAEYLRSNITMLKWMISQGYGDARTMARRVENMEK 658
QAFEL+DA+AERS +G I LSEE VAEYLRSN+ ++K MI++GY DART+ RR+ ME+
Sbjct 581 QAFELTDATAERSCSGSTIKLSEETVAEYLRSNVVLMKNMIARGYQDARTLLRRIAKMEE 640
Query 659 WLANPSLLKADADAEYTKVYEIDLADIKEPILCCPNDPDDAKLLSDVQGDKIDEVFIGSC 718
WLANPSL+ DADAEY V E++L +IKEPI+ PNDPD+ KL+S+ GD I EVFIGSC
Sbjct 641 WLANPSLMSGDADAEYADVIEVNLDEIKEPIVAAPNDPDNVKLMSECAGDVIHEVFIGSC 700
Query 719 MTNIGHFRAAGQLLEKVPSGSLTTRLWLAPPTRMDEHQLMEEGFYNTYGRAGARTEMPGC 778
MTNIGH+RAA ++LE +G++ RLW+ PPTRMDE QL EEG Y + AGARTEMPGC
Sbjct 701 MTNIGHYRAAAKILE--GAGTVKGRLWICPPTRMDEQQLREEGIYGIFAAAGARTEMPGC 758
Query 779 SLCMGNQARVAPNTTVVSTSTRNFPNRLGQGSNVYLASAELASVAAVLGKLPTPEEYQQY 838
SLCMGNQARV TV STSTRNF NR+G+G+ VYL SAELA+V A+LGK+PT EEY
Sbjct 759 SLCMGNQARVEDGVTVFSTSTRNFNNRMGKGAQVYLGSAELAAVCALLGKIPTVEEYLAI 818
Query 839 AAQ-IDSMSADIYKYLNFDKMGEY 861
++ + ++Y+YLNF+++ +
Sbjct 819 VSEKVAPFEGELYRYLNFNEIDNF 842
>P56418 Aconitate hydratase B [Helicobacter pylori (strain ATCC
700392 / 26695)]
Length=852
Score = 944 bits (2440), Expect = 0.0
Identities = 496/870 (57%), Positives = 626/870 (72%), Gaps = 34/870 (4%)
Query 2 LEAYRQHVEERAALGVPPKPLDDAQTADLVELLKNPPAGEEAFLVDLLENRVPAGVDQAA 61
LE Y++ V ER + G+PP PL+ Q +VE+L P AF +LL +RV GVD+ A
Sbjct 5 LEDYKKSVSERGSEGIPPLPLNAKQVQAVVEILTKDPTNA-AFAKELLIHRVSPGVDEGA 63
Query 62 YVKAAFLAALAKGEATSPLVSKERAVYLLGTMLGGYNVAPLVELLE--DADLGALAADAL 119
VKA FLA L++ + +S A LLGTMLGGYNV PL+ LE D ++ +A AL
Sbjct 64 KVKAEFLAKLSQKKLECVHISALEATTLLGTMLGGYNVEPLIMGLESQDKNIAKESAKAL 123
Query 120 KKTLLVFDAFHDVADKAKAGNTNAKAVLQSWADAEWFTSRKDVPEEIKLTVFKVTGETNT 179
K TLLV+ +F +A +K N AK VL+SWA+AEWF +++ + E I+ VFK+ GETNT
Sbjct 124 KTTLLVYGSFDKIAAMSKT-NALAKEVLESWANAEWFLNKEPLNECIEACVFKIDGETNT 182
Query 180 DDLSPAQDAWSRPDIPLHANAMLKNERDGINPEKPGEVGPLSQIKELIAKGNQVAYVGDV 239
DDLSPA DA++R DIPLHA AMLKN + +IK + KG VAYVGDV
Sbjct 183 DDLSPASDAFTRSDIPLHAKAMLKNRIENYE----------QRIKAIKTKGVPVAYVGDV 232
Query 240 VGTGSSRKSATNSVLWFFGDEIAHIPNKKDGGYCLGSKIAPIFFNTMEDAGALPVEIDVA 299
VGTGSSRKSATNS++W FG +I +PNK+ GG +G IAPIFF T ED+GALP+ DV
Sbjct 233 VGTGSSRKSATNSIMWHFGKDIPFVPNKRSGGIVIGGVIAPIFFATCEDSGALPIVADVK 292
Query 300 NMNMGDEIVLKIDHAAAKVTAFKNGEQIAESELKTPVLLDEVRAGGRINLIVGRGLTTKA 359
++ GD ++KI ++T N + ++ +L+ LLDEVRA GRI LI+GRGLT KA
Sbjct 293 DLKEGD--LIKIYPYKGEITL--NDKVVSTFKLEPETLLDEVRASGRIPLIIGRGLTNKA 348
Query 360 REALGLEPSTLFRTPVQPAATGKGFTLAQKMVGRACGLPEGQGVIPGTYCEPKMTTVGSQ 419
R+ LGL S F+ P P + KG+TLAQK+VG ACG+ +G++PGTYCEPK+TTVGSQ
Sbjct 349 RKFLGLGESEAFKKPSAPKSDAKGYTLAQKIVGHACGV---KGILPGTYCEPKVTTVGSQ 405
Query 420 DTTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPKPVDVQMQHTLPDFIMNRGGVSLRP 479
DTTG MTRDE+K+LA L F A V+QSFCHTAAYPKP DV + TLP FI RGGV+L P
Sbjct 406 DTTGAMTRDEVKELASLKFDAPFVLQSFCHTAAYPKPSDVSLHATLPGFITQRGGVALHP 465
Query 480 GDGIIHSWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLV 539
GDG+IH+WLNRM LPDT+GTGGDSHTRFP+GISFPAGSGLVAFAA TG MPL+MPESVLV
Sbjct 466 GDGVIHTWLNRMGLPDTLGTGGDSHTRFPLGISFPAGSGLVAFAAVTGTMPLNMPESVLV 525
Query 540 KFKGKMQPGITLRDLVHAIPYYAIKEGDLTVEKKGKKNIFSGRILEIDLTEMETDLTVEQ 599
+FKG+M PGITLRDLV+AIPYYAIK+G LTVEKKGK N+F+GRILEI E D+ +EQ
Sbjct 526 RFKGEMNPGITLRDLVNAIPYYAIKKGLLTVEKKGKINVFNGRILEI---EGLPDIKMEQ 582
Query 600 AFELSDASAERSAAGCAITLSEEKVAEYLRSNITMLKWMISQGYGDARTMARRVENMEKW 659
AFELSDASAERSAA C + L++E + EYL+SNI ++ MI+ GY D T+ +R + M+ W
Sbjct 583 AFELSDASAERSAAACVVRLNKEPMIEYLKSNIKLIDEMIASGYEDKETLKKRRDAMQAW 642
Query 660 LANPSLLKADADAEYTKVYEIDLADIKEPILCCPNDPDDAKLLSDVQGD-------KIDE 712
+ NP LL+ D++A+Y V EID+A+I EPIL CPNDPDD LS+V D IDE
Sbjct 643 VDNPVLLEPDSNAQYAAVIEIDVAEITEPILACPNDPDDVATLSEVLADTTGKRPHAIDE 702
Query 713 VFIGSCMTNIGHFRAAGQLLEKVPSGSLTTRLWLAPPTRMDEHQLMEEGFYNTYGRAGAR 772
VFIGSCMTNIGHFRA G++++ P RLW+ PP++MDE +L+ EG+Y +G AGAR
Sbjct 703 VFIGSCMTNIGHFRAFGEIVKNAPPSQ--ARLWVVPPSKMDEQELINEGYYAIFGAAGAR 760
Query 773 TEMPGCSLCMGNQARVAPNTTVVSTSTRNFPNRLGQGSNVYLASAELASVAAVLGKLPTP 832
TE+PGCSLCMGNQARV N V STSTRNF NR+G+G+ VYL SAEL + A+LG++PT
Sbjct 761 TEVPGCSLCMGNQARVRDNAVVFSTSTRNFDNRMGRGAKVYLGSAELGAACALLGRIPTK 820
Query 833 EEYQQYAAQ-IDSMSADIYKYLNFDKMGEY 861
EEY ++ ++S IY+Y+NF+ M +
Sbjct 821 EEYMNLVSEKLESQKDKIYRYMNFNLMENF 850
>Q9ZL64 Aconitate hydratase B [Helicobacter pylori (strain J99
/ ATCC 700824)]
Length=852
Score = 941 bits (2432), Expect = 0.0
Identities = 494/870 (57%), Positives = 625/870 (72%), Gaps = 34/870 (4%)
Query 2 LEAYRQHVEERAALGVPPKPLDDAQTADLVELLKNPPAGEEAFLVDLLENRVPAGVDQAA 61
LE Y++ V ER + G+PP PL+ Q +VE+L P AF +LL +RV GVD+ A
Sbjct 5 LEDYKKSVLERKSEGIPPLPLNAKQVEAVVEILMKDPTNA-AFAKELLIHRVSPGVDEGA 63
Query 62 YVKAAFLAALAKGEATSPLVSKERAVYLLGTMLGGYNVAPLVELLE--DADLGALAADAL 119
VKA FLA L++ + P +S A LLGTMLGGYNV PL+ LE D ++ +A AL
Sbjct 64 KVKAEFLAQLSQKKLECPHISALEATTLLGTMLGGYNVEPLIVGLESQDKNIAKESAKAL 123
Query 120 KKTLLVFDAFHDVADKAKAGNTNAKAVLQSWADAEWFTSRKDVPEEIKLTVFKVTGETNT 179
K TLLV+ +F +A +K N AK VL+SWA+AEWF +++ + E I+ VFK+ GETNT
Sbjct 124 KTTLLVYGSFDKIAAMSKT-NALAKEVLESWANAEWFLNKEPLNECIEACVFKIDGETNT 182
Query 180 DDLSPAQDAWSRPDIPLHANAMLKNERDGINPEKPGEVGPLSQIKELIAKGNQVAYVGDV 239
DDLSPA DA++R DIPLHA AMLKN + +I+ + KG VAYVGDV
Sbjct 183 DDLSPASDAFTRSDIPLHAKAMLKNRIENYE----------QRIEAIKTKGVPVAYVGDV 232
Query 240 VGTGSSRKSATNSVLWFFGDEIAHIPNKKDGGYCLGSKIAPIFFNTMEDAGALPVEIDVA 299
VGTGSSRKSATNS++W FG +I +PNK+ GG +G IAPIFF T ED+GALP+ DV
Sbjct 233 VGTGSSRKSATNSIMWHFGKDIPFVPNKRSGGIVIGGVIAPIFFATCEDSGALPIVADVK 292
Query 300 NMNMGDEIVLKIDHAAAKVTAFKNGEQIAESELKTPVLLDEVRAGGRINLIVGRGLTTKA 359
++ GD ++KI ++T N + ++ +L+ LLDEVRA GRI LI+GRGLT KA
Sbjct 293 DLKEGD--IIKIYPYKGEITL--NDKVVSTFKLEPETLLDEVRASGRIPLIIGRGLTNKA 348
Query 360 REALGLEPSTLFRTPVQPAATGKGFTLAQKMVGRACGLPEGQGVIPGTYCEPKMTTVGSQ 419
R+ LGL S F+ P P + KG+TLAQK+VG ACG+ +G++PG YCEPK+TTVGSQ
Sbjct 349 RKFLGLGESEAFKKPSAPKSDAKGYTLAQKIVGHACGV---KGILPGAYCEPKVTTVGSQ 405
Query 420 DTTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPKPVDVQMQHTLPDFIMNRGGVSLRP 479
DTTG MTRDE+K+LA L F A V+QSFCHTAAYPKP DV + TLP FI RGGV+L P
Sbjct 406 DTTGAMTRDEVKELASLKFDAPFVLQSFCHTAAYPKPSDVSLHATLPGFITQRGGVALHP 465
Query 480 GDGIIHSWLNRMLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAAATGVMPLDMPESVLV 539
GDG+IH+WLNRM LPDT+GTGGDSHTRFP+GISFPAGSGLVAFAA TG MPL+MPESVLV
Sbjct 466 GDGVIHTWLNRMGLPDTLGTGGDSHTRFPLGISFPAGSGLVAFAAVTGTMPLNMPESVLV 525
Query 540 KFKGKMQPGITLRDLVHAIPYYAIKEGDLTVEKKGKKNIFSGRILEIDLTEMETDLTVEQ 599
+FKG+M PGITLRDLV+AIPYYAIK+G LTVEKKGK N+F+GRILEI E D+ +EQ
Sbjct 526 RFKGEMNPGITLRDLVNAIPYYAIKKGLLTVEKKGKINVFNGRILEI---EGLPDIKMEQ 582
Query 600 AFELSDASAERSAAGCAITLSEEKVAEYLRSNITMLKWMISQGYGDARTMARRVENMEKW 659
AFELSDASAERSAA C + L++E + EYL+SNI ++ MI+ GY D T+ +R + M+ W
Sbjct 583 AFELSDASAERSAAACVVRLNKEPMIEYLKSNIKLIDEMIASGYEDKETLKKRRDAMQAW 642
Query 660 LANPSLLKADADAEYTKVYEIDLADIKEPILCCPNDPDDAKLLSDVQGD-------KIDE 712
+ P LL+ D++A+Y V EID+A+I EPIL CPNDPDD LS+V D IDE
Sbjct 643 VDKPVLLEPDSNAQYAAVIEIDVAEITEPILACPNDPDDVATLSEVLADTTGKRPHAIDE 702
Query 713 VFIGSCMTNIGHFRAAGQLLEKVPSGSLTTRLWLAPPTRMDEHQLMEEGFYNTYGRAGAR 772
VFIGSCMTNIGHFRA G++++ P RLW+ PP++MDE +L+ EG+Y +G AGAR
Sbjct 703 VFIGSCMTNIGHFRAFGEIVKNAPPSQ--ARLWVVPPSKMDEQELINEGYYAIFGAAGAR 760
Query 773 TEMPGCSLCMGNQARVAPNTTVVSTSTRNFPNRLGQGSNVYLASAELASVAAVLGKLPTP 832
TE+PGCSLCMGNQARV N V STSTRNF NR+G+G+ VYL SAEL + A+LG++PT
Sbjct 761 TEVPGCSLCMGNQARVRDNAVVFSTSTRNFDNRMGRGAKVYLGSAELGAACALLGRIPTK 820
Query 833 EEYQQYAAQ-IDSMSADIYKYLNFDKMGEY 861
EEY ++ ++S IY+Y+NF+ M +
Sbjct 821 EEYMNLVSEKLESQKDKIYRYMNFNLMENF 850
>P81291 Isopropylmalate/citramalate isomerase large subunit [Methanocaldococcus
jannaschii (strain ATCC 43067 / DSM 2661 /
JAL-1 / JCM 10045 / NBRC 100440)]
Length=424
Score = 128 bits (322), Expect = 1e-34
Identities = 127/477 (27%), Positives = 205/477 (43%), Gaps = 80/477 (17%)
Query 383 GFTLAQKMVGRACGLPEGQGVIPGTYCEPKMTTVGSQDTTGPMTRDELKDLACLG-FSAD 441
G T+ +K++ +A G E V PG + D TGP+T + LK+ ++ +
Sbjct 2 GMTIVEKILAKASGKKE---VSPGDIVMANIDVAMVHDITGPLTVNTLKEYGIEKVWNPE 58
Query 442 LVMQSFCHTAAYPKPVDVQMQHTLPDFIMNRG---GVSLRPGDGIIHSWLNRM--LLPDT 496
++ F H + + F+ +G +R +G+ H L + P
Sbjct 59 KIVILFDHQVPADSIKAAENHILMRKFVKEQGIKYFYDIR--EGVCHQVLPEKGHVAPGE 116
Query 497 VGTGGDSHT-------RFPIGISFPAGSGLVAFAAATGVMPLDMPESVLVKFKGKMQPGI 549
V G DSHT F GI GS +A ATG + +PE++ G +QP +
Sbjct 117 VVVGADSHTCTHGAFGAFATGI----GSTDMAHVFATGKLWFKVPETIYFNITGDLQPYV 172
Query 550 TLRDLVHAI---------PYYAIKEGDLTVEKKGKKNIFSGRILEIDLTEMETDLTVEQA 600
T +D++ +I Y A + G TV+K + I T++ +E
Sbjct 173 TSKDVILSIIGEVGVDGATYKACQFGGETVKK-----------MSIASRMTMTNMAIEMG 221
Query 601 FELSDASAERSAAGCAITLSEEKVAEYLRSNITMLKWMISQGYGDARTMARRVENMEKWL 660
+ I +EK +Y++ + + +G R
Sbjct 222 GKTG------------IIEPDEKTIQYVKEAM--------KKHGTERPF----------- 250
Query 661 ANPSLLKADADAEYTKVYEIDLADIKEPILCCPNDPDDAKLLSDVQGDKIDEVFIGSCMT 720
++K D DAE+ +VYEI+ AD EP+ CP++ D+ K +V G ID+VFIGSC
Sbjct 251 ---EVIKGDEDAEFAEVYEIE-ADKIEPVFACPHNVDNVKQAREVAGKPIDQVFIGSCTN 306
Query 721 -NIGHFRAAGQLLEKVPSGSLTTRLWLAPPTRMDEHQLMEEGFYNTYGRAGARTEMPGCS 779
+ R A +++EK + R+ + P +R + + ++EG + + G P CS
Sbjct 307 GRLEDLRMAIKIIEKHGGIADDVRVVVTPASREEYLKALKEGIIEKFLKYGCVVTNPSCS 366
Query 780 LCMGNQARV-APNTTVVSTSTRNFPNRLGQ-GSNVYLASAELASVAAVLGKLPTPEE 834
CMG+ V P VSTS RNF R G + +YLAS A+ AV G+L P +
Sbjct 367 ACMGSLYGVLGPGEVCVSTSNRNFRGRQGSLEAEIYLASPITAAACAVKGELVDPRD 423
>O28084 3-isopropylmalate dehydratase large subunit 2 [Archaeoglobus
fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
100126 / VC-16)]
Length=416
Score = 127 bits (318), Expect = 3e-34
Identities = 123/463 (27%), Positives = 205/463 (44%), Gaps = 59/463 (13%)
Query 383 GFTLAQKMVGRACGLPEGQGVIPGTYCEPKMTTVGSQDTTGPMTRDELKDLACLGFSADL 442
G T+A+K++ G ++ + QD T P+ +L +L +AD
Sbjct 2 GKTIAEKILSEK----SKSDAYAGDIVVAEIDQIALQDGTAPLAIRQLMELGTEVRAADR 57
Query 443 VMQSFCHTAAYPKPVDVQMQHTLPDFIMNRGGVSLRPGDGIIHS-WLNRMLLPDTVGTGG 501
H A P+ Q + +F G PG+GIIH + R + P + G
Sbjct 58 THFFVDHAAPSPRRELSNDQKFIYEFAKKVGADFNPPGEGIIHQIMVERYVKPGDLAVGA 117
Query 502 DSHTRFPIGI-SFPAGSGL--VAFAAATGVMPLDMPESVLVKFKGKMQPGITLRDLVHAI 558
DSHT GI +F G G VA A A G +PES V+ G + G+ +D++ +
Sbjct 118 DSHTCTYGGIGAFSTGMGSTDVAVAIALGKNWFRVPESFRVQLDGSLPKGVFAKDVILKL 177
Query 559 PYYAIKEGDLTVEKKGKKNI-FSGRILEIDLTEMETDLTVEQAFELSDASAERSAAGCAI 617
GDL V+ K + F G E ++TVE+ +++ + E A I
Sbjct 178 I------GDLGVDGATYKALEFHGECAE--------NMTVEERLTIANMAVE-CGAKAGI 222
Query 618 TLSEEKVAEYLRSNITMLKWMISQGYGDARTMARRVENMEKWLANPSLLKADADAEYTKV 677
S+E ++L + R + E +KAD DAEY K
Sbjct 223 FESDENTRKFLAE------------------LGREGDFRE--------VKADEDAEYEKE 256
Query 678 YEIDLADIKEPILCCPNDPDDAKLLSDVQGDKIDEVFIGSCMT-NIGHFRAAGQLLE--K 734
+D++ + P++ P++ D+ +S+V+G ++++V+IG+C + A ++L+ K
Sbjct 257 IYMDVSSLV-PVVSKPHNVDNVAEISEVEGTEVNQVYIGTCTNGRLSDLEVAARILKGRK 315
Query 735 VPSGSLTTRLWLAPPTRMDEHQLMEEGFYNTYGRAGARTEMPGCSLCMG-NQARVAPNTT 793
V G RL + P +R Q +++G + AG PGC C+G +Q +A
Sbjct 316 VKEG---VRLIVVPASRRVYLQALDKGLIRVFVEAGGMVLNPGCGPCVGIHQGILADGEV 372
Query 794 VVSTSTRNFPNRLGQ-GSNVYLASAELASVAAVLGKLPTPEEY 835
+ST RNF R+G + ++LAS A+ +AV G + P E+
Sbjct 373 CISTQNRNFKGRMGNPNAEIFLASPATAAASAVKGYIADPREF 415
>Q4JC09 3-isopropylmalate dehydratase large subunit [Sulfolobus
acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC
15157 / NCIMB 11770)]
Length=414
Score = 124 bits (311), Expect = 2e-33
Identities = 119/457 (26%), Positives = 206/457 (45%), Gaps = 58/457 (13%)
Query 385 TLAQKMVGRACGLPEGQGVIPGTYCEPKMTTVGSQDTTGPMTRDELKDLACLG-FSADLV 443
TL +K++ RA G+ V PG E K+ V D TG + ++D+ L F + +
Sbjct 4 TLTEKILSRA----SGKNVSPGDVTEIKVDLVAFHDLTGYHVIEVMEDVGTLKVFDREKL 59
Query 444 MQSFCHTAAYPKPVDVQMQHTLPDFIMNRGGVSLRP-GDGIIHS-WLNRMLLPDTVGTGG 501
+ +F H A P ++Q + +F+ + GI+H + R P V
Sbjct 60 VIAFDHLAPPPDVRSAEIQGQIRNFVKKTSVPNFYDINSGILHQIMIERYANPGQVIVAA 119
Query 502 DSHTRFPIGI-SFPAGSGL--VAFAAATGVMPLDMPESVLVKFKGKMQPGITLRDLVHAI 558
DSHT + +F G G VA A TG + +P+ + +GK I +D+ I
Sbjct 120 DSHTSTSGAVGAFAQGLGASDVAAAVITGKTWVMVPQPFKITLEGKPARWINGKDIALKI 179
Query 559 PYYAIKEGDLTVEKKGKKNIFSGRILEIDLTEMETDLTVEQAFELSDASAERSAAGCAIT 618
GD K + F+G LEI + E + ++ +S+ E +A +
Sbjct 180 L------GDF------KADYFNGMSLEIFVKEPSA-VPMDFRATVSNMGIEMNA-DALMF 225
Query 619 LSEEKVAEYLRSNITMLKWMISQGYGDARTMARRVENMEKWLANPSLLKADADAEYTKVY 678
+ +++ Y+++ ++GY P ++ D+DA+Y Y
Sbjct 226 VPDQETFNYIKT---------ARGY------------------EPQMVTPDSDAKYVDEY 258
Query 679 EIDLADIKEPILCCPNDPDDAKLLSDVQGDKIDEVFIGSCMT-NIGHFRAAGQLLEKVPS 737
IDL+ + +P++ P+ D+ K +++V+G +D+VFIGSC I A ++L+
Sbjct 259 NIDLSKL-DPLVAAPHSVDNVKSVNEVEGTPVDQVFIGSCTNGRISDLEMAAKILK---G 314
Query 738 GSLTTRLWLAPPTRMDEHQLMEEGFYNTYGRAGARTEMPGCSLCMGNQARVA-PNTTVVS 796
+ TR + P + + +E G+ T AGA C C+G +A P T++S
Sbjct 315 KKVKTRTIVIPASYQLFKKALELGYVQTLADAGAIITYGTCGPCLGGHFGIAGPGETIIS 374
Query 797 TSTRNFPNRLGQ-GSNVYLASAELASVAAVLGKLPTP 832
TS+RNF R+G + VYL+ +A+ A+ GK+ P
Sbjct 375 TSSRNFKGRMGSPDAKVYLSGPAVAAATALEGKITDP 411
>B2KBD7 3-isopropylmalate dehydratase large subunit [Elusimicrobium
minutum (strain Pei191)]
Length=418
Score = 124 bits (311), Expect = 2e-33
Identities = 121/462 (26%), Positives = 205/462 (44%), Gaps = 62/462 (13%)
Query 385 TLAQKMVGRACGLPEGQGVIPGTYCEPKMTTVGSQDTTGPMTRDELKDLACLGFSADLVM 444
T+A+K++ G+ V G + + QD TGP+T +ELK +
Sbjct 4 TIAEKIISNH----SGRRVKAGEFVIADVDLTAVQDGTGPLTVEELKKAGFTKLANPART 59
Query 445 QSFC-HTAAYPKPVDVQMQHTLPDFIMNRGGVSLRPGDGIIHSWL-NRMLLPDTVGTGGD 502
F H A P+ Q L +F G + G+G+ H L + + P + G D
Sbjct 60 ILFIDHAAPSPRKELSNSQVVLRNFAKETGAILSEIGEGVCHQLLAEKYVNPGEILIGAD 119
Query 503 SHTRFPIGI-SFPAGSGL--VAFAAATGVMPLDMPESVLVKFKGKMQPGITLRDLV-HAI 558
SHT + +F G G VA A G L P++ ++ +G + G+ +DL+ H I
Sbjct 120 SHTCTGGALGAFATGMGSTDVAVGMALGKTWLKAPQTFKIEVEGAFKKGVGAKDLILHLI 179
Query 559 PYYAIKEGDLTVEKKGKKNI-FSGRILEIDLTEMETDLTVEQAFELSDASAERSAAGCAI 617
G + + K + F G + ++ + F L++ + E + A +
Sbjct 180 -------GVIGADGATYKALEFHGSTIR--------NMEMADRFTLANMAVE-AGAKAGL 223
Query 618 TLSEEKVAEYLRSNITMLKWMISQGYGDARTMARRVENMEKWLANPSLLKADADAEYTKV 677
++EK YL +G GD N L+ AD A+Y KV
Sbjct 224 FFTDEKTRAYLAE----------RGRGD----------------NFKLISADEGADYEKV 257
Query 678 YEIDLADIKEPILCCPNDPDDAKLLSDVQGDKIDEVFIGSCMT-NIGHFRAAGQLL--EK 734
+ID + + EP + CP+ D+ K + +++ K+++VFIG+C I R A ++L +K
Sbjct 258 IKIDASSL-EPTVSCPHTVDNTKTVGELKDIKVNQVFIGTCTNGRIEDLRIAAEILKDKK 316
Query 735 VPSGSLTTRLWLAPPTRMDEHQLMEEGFYNTYGRAGARTEMPGCSLCMGNQARVAPNTTV 794
V G TR ++ P +R ++EG + +AGA + PGC C+G + + V
Sbjct 317 VNPG---TRTFITPASRDVMLAALKEGLIEIFVKAGASVQTPGCGPCVGVHGGILGDGEV 373
Query 795 -VSTSTRNFPNRLGQGSN-VYLASAELASVAAVLGKLPTPEE 834
++T RNF R+G +YL+S +A+ +A+ G + P E
Sbjct 374 CLATQNRNFQGRMGNTKGFIYLSSPAVAAYSALKGYISDPRE 415
>Q58409 Methanogen homoaconitase large subunit [Methanocaldococcus
jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
10045 / NBRC 100440)]
Length=420
Score = 121 bits (303), Expect = 3e-32
Identities = 122/461 (26%), Positives = 210/461 (46%), Gaps = 67/461 (15%)
Query 385 TLAQKMVGRACGLPEGQGVIPGTYCEPKMTTVGSQDTTGPMTRDELKDLACLGFSADLVM 444
TL +K++ + G V G E ++ + D T P+ LK+++ ++ D ++
Sbjct 2 TLVEKILSKKVGYE----VCAGDSIEVEVDLAMTHDGTTPLAYKALKEMSDSVWNPDKIV 57
Query 445 QSFCHTAAYPKPVDVQMQHTLPDFIMNRGGVSL-RPGDGIIHSWL-NRMLLPDTVGTGGD 502
+F H +MQ +F+ G + + G+GI H L +LP+ GGD
Sbjct 58 VAFDHNVPPNTVKAAEMQKLALEFVKRFGIKNFHKGGEGICHQILAENYVLPNMFVAGGD 117
Query 503 SHTRFPIGI-SFPAGSGL--VAFAAATGVMPLDMPESVLVKFKGKMQPGITLRDLVHAI- 558
SHT +F G G +A+ ATG + +P+++ V GK + ++ +D+V +
Sbjct 118 SHTCTHGAFGAFATGFGATDMAYIYATGETWIKVPKTIRVDIVGKNE-NVSAKDIVLRVC 176
Query 559 --------PYYAIKEGDLTVEKKGKKNIFSGRILEIDLT-EMETDLTVEQAFELSDASAE 609
Y AI+ G V K GR+ ++ EM V +A E++ +
Sbjct 177 KEIGRRGATYMAIEYGGEVV----KNMDMDGRLTLCNMAIEMGGKTGVIEADEITYDYLK 232
Query 610 RSAAGCAITLSEEKVAEYLRSNITMLKWMISQGYGDARTMARRVENMEKWLANPSLLKAD 669
+ LS+E +A+ + IT+ +
Sbjct 233 KERG-----LSDEDIAKLKKERITVNR--------------------------------- 254
Query 670 ADAEYTKVYEIDLADIKEPILCCPNDPDDAKLLSDVQGDKIDEVFIGSCMT-NIGHFRAA 728
+A Y K EID+ D++E + P+ PD+ K +SDV+G +I++VFIGSC + R A
Sbjct 255 DEANYYKEIEIDITDMEEQV-AVPHHPDNVKPISDVEGTEINQVFIGSCTNGRLSDLREA 313
Query 729 GQLLEKVPSGSLTTRLWLAPPTRMDEHQLMEEGFYNTYGRAGARTEMPGCSLCMG-NQAR 787
+ L K +L + P ++ Q ++EG + + +AGA PGC C+G +Q
Sbjct 314 AKYL-KGREVHKDVKLIVIPASKKVFLQALKEGIIDIFVKAGAMICTPGCGPCLGAHQGV 372
Query 788 VAPNTTVVSTSTRNFPNRLGQ-GSNVYLASAELASVAAVLG 827
+A +ST+ RNF R+G S +YLAS ++A+++AV G
Sbjct 373 LAEGEICLSTTNRNFKGRMGHINSYIYLASPKIAAISAVKG 413
>Q9ZNE0 Homoaconitase large subunit [Thermus thermophilus (strain
ATCC BAA-163 / DSM 7039 / HB27)]
Length=418
Score = 117 bits (294), Expect = 4e-31
Identities = 121/412 (29%), Positives = 174/412 (42%), Gaps = 73/412 (18%)
Query 450 TAAYPKPVDVQMQHTLPDFIMN-------------RGGVSLRP-GDGIIHSWL--NRMLL 493
T YP+ V + + H P + R G+ + G G+ H L +
Sbjct 51 TPRYPERVSIVIDHVAPAANLEVAKAQKEIREWGKRHGIRVFDVGRGVCHQVLIEEGLAQ 110
Query 494 PDTVGTGGDSH-TRFPIGISFPAGSGL--VAFAAATGVMPLDMPESVLVKFKGKMQPGIT 550
P V G DSH T + +F G G +A AAA+G L +PESV V F+G++ G+T
Sbjct 111 PGWVVVGSDSHSTTYGAVGAFGTGMGATDIALAAASGRTWLRVPESVKVVFRGRLPKGVT 170
Query 551 LRDLVHAIPYYAIKEGDLTVEKKGKKNIFSGRILEIDLTEMETDLTVEQAFELSDASAER 610
+D + EG + +EI L + LT + L++ + E
Sbjct 171 AKDAALEMVRLLTAEGATYMA------------VEIHLLDGAEALTRGERMTLANLTVEA 218
Query 611 SAAGCAITLSEEKVAEYLRSNITMLKWMISQGYGDARTMARRVENMEKWLANPSLLKADA 670
A + S E + Y RV P L D
Sbjct 219 GAKAGLVVPSGEILEMY------------------------RV---------PDWLYPDP 245
Query 671 DAEYTKVYEIDLADIKEPILCCPNDPDDAKLLSDVQGDKIDEVFIGSCMTN-IGHFRAAG 729
DA Y K EIDL+ + P + P D+ ++ V+G ++D+VFIG+C I RAA
Sbjct 246 DARYAKEVEIDLSALT-PRVSVPFYVDNVHEVAQVKGKRVDQVFIGTCTNGRIEDLRAAA 304
Query 730 QLLE--KVPSGSLTTRLWLAPPTRMDEHQLMEEGFYNTYGRAGARTEMPGCSLCMGNQAR 787
++L KV RL + P + + +G T AGA PGC CMG
Sbjct 305 EVLRGRKVAPW---VRLLVVPASSQVLEEAARDGTLLTLLEAGATIGTPGCGPCMGRHMG 361
Query 788 V-APNTTVVSTSTRNFPNRLGQ-GSNVYLASAELASVAAVLGKLPTPEEYQQ 837
V AP VSTS RNF R+G + +YLAS +A+ +AV G L TPEE ++
Sbjct 362 VLAPGEVCVSTSNRNFRGRMGAPDAEIYLASPRVAAASAVAGYLTTPEELEE 413
>Q0QLE2 2,3-dimethylmalate dehydratase large subunit [Eubacterium
barkeri]
Length=420
Score = 95.1 bits (235), Expect = 1e-23
Identities = 105/371 (28%), Positives = 163/371 (44%), Gaps = 70/371 (19%)
Query 482 GIIHSWLNR--MLLPDTVGTGGDSHT-------RFPIGISFPAGSGLVAFAAATGVMPLD 532
GI H+ L ++ V G DSHT F G+ GS +A ATG
Sbjct 101 GIEHALLPEKGLVAAGDVVIGADSHTCTYGALGAFSTGV----GSTDMAVGMATGKAWFK 156
Query 533 MPESVLVKFKGKMQPGITLRDLV-HAIPYYAIKEGDLTVEKKGKKNIFSGRILEIDLTEM 591
+P ++ G + ++ +DL+ H I + +G L + F+G +
Sbjct 157 VPAALRFNLTGTLNKNVSGKDLILHIIGMIGV-DGALYRSME-----FTGPGVAC----- 205
Query 592 ETDLTVEQAFELSDASAERSAAGCAITLSEEKVAEYLRSNITMLKWMISQGYGDARTMAR 651
L+++ F +S+ + E + ++ ++ +M G GD + A
Sbjct 206 ---LSMDDRFTISNMAIEAGGKNGIFPVDDQTIS-----------YMEEHGSGDYKVYA- 250
Query 652 RVENMEKWLANPSLLKADADAEYTKVYEIDLADIKEPILCCPNDPDDAKLLSDVQGD-KI 710
ADADA Y K ++IDL+ +K + P+ P++ K + ++ I
Sbjct 251 ----------------ADADAVYEKTFDIDLSQLKSTV-AFPHLPENTKTVDAIEEPVTI 293
Query 711 DEVFIGSCMTNIGHF----RAAGQLLEK-VPSGSLTTRLWLAPPTRMDEHQLMEEGFYNT 765
D+V IGSC TN G F RAA L K V G R+ + P T ME G+
Sbjct 294 DQVVIGSC-TN-GRFEDLKRAADILRGKHVKKG---VRMLVIPATHKIYLDAMEAGYLRE 348
Query 766 YGRAGARTEMPGCSLCMGNQARV-APNTTVVSTSTRNFPNRLGQ-GSNVYLASAELASVA 823
+ AGA P C C+G + A VST+ RNF R+G S VYLAS E+A+ +
Sbjct 349 FIEAGATISTPTCGPCLGGYMGILAEGERCVSTTNRNFVGRMGHVDSEVYLASPEVAAAS 408
Query 824 AVLGKLPTPEE 834
A+LG++ TP+E
Sbjct 409 AILGRIATPDE 419
>Q92412 Homoaconitase, mitochondrial [Emericella nidulans (strain
FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)]
Length=776
Score = 96.3 bits (238), Expect = 2e-23
Identities = 112/473 (24%), Positives = 194/473 (41%), Gaps = 37/473 (8%)
Query 385 TLAQKMVGR-ACGLPEGQGVIPGTYCEPKMTTVGSQDTTGPMTRDELKDLACLGFSADLV 443
TL +K+V + + GLP+G+ V G Y + + D + P + A + D +
Sbjct 67 TLTEKIVQKYSVGLPQGKFVKSGDYVTIQPHRCMTHDNSWPCALKFMSIGASRLHNPDQI 126
Query 444 MQSFCHTAAYPKPVDVQMQHTLPDFIMNRGGVSLRPGDGIIHSWL--NRMLLPDTVGTGG 501
+ + H +++ + +F G G GI H + P T+
Sbjct 127 VMTLDHDVQNKSDKNLKKYRQIEEFATQHGVEFYPAGRGIGHQIMIEEGFAWPGTLAVAS 186
Query 502 DSHTRFPIGISFPAGSGLVAFAAA----TGVMPLDMPESVLVKFKGKMQPGITLRDLVHA 557
DSH+ G+ G+ +V AA TG +P V FKG + PG+T +D++ A
Sbjct 187 DSHSNMYGGVGC-LGTPIVRTDAASVWATGKTWWQIPPVAKVTFKGVLPPGVTGKDVIVA 245
Query 558 IPYYAIKEGDLTVEKKGKKNIFSGRILEIDLTEMETDLTVEQAFELSDASAERSAAGCAI 617
+ K ++ + I E L+V+ +++ + E A
Sbjct 246 L-----------CGLFNKDDVLNHAIEFTGSEETMRSLSVDTRLTIANMTTEWGALSGLF 294
Query 618 TLSEEKVAEYLRSNITMLKWMISQGYGDARTMARRVEN-MEKWLANPSLLKADADAEYTK 676
+ + + +LR T ++ G R R +E+ NP L AD A+Y K
Sbjct 295 PI-DSVLKGWLRGKATTAAMGLADGPFKTRAAERFTHPLLEQLFENP--LTADKGAKYAK 351
Query 677 VYEIDLADIKEPILCCPNDPDDAKLLSDV--QGDKIDEVFIGSCM-TNIGHFRAAGQLLE 733
+DL+ + P + PN A L ++ Q K+D+ ++ SC + AA ++ +
Sbjct 352 ELFLDLSSL-SPYVSGPNSVKVATPLKELEAQNIKVDKAYLVSCTNSRASDIAAAAKVFK 410
Query 734 --------KVPSGSLTTRLWLAPPTRMDEHQLMEEGFYNTYGRAGARTEMPGCSLCMG-N 784
K+P + + ++A + ++ G + T AGA GC C+G
Sbjct 411 EAAEKNGGKIPKIADGVKFYIAAASIPEQLAAEGNGDWQTLLEAGATQLPAGCGPCIGMG 470
Query 785 QARVAPNTTVVSTSTRNFPNRLGQ-GSNVYLASAELASVAAVLGKLPTPEEYQ 836
Q + P +S S RNF R+G + YL S E+ + +A+ GKL P YQ
Sbjct 471 QGLLEPGEVGISASNRNFKGRMGSTEAKAYLGSPEVVAASALSGKLSGPGWYQ 523
Score = 22.3 bits (46), Expect = 1.5
Identities = 11/29 (38%), Positives = 18/29 (62%), Gaps = 2/29 (7%)
Query 213 KPGEVGPLSQIKELIAKGNQVAYVGDVVG 241
K GE+ P ++E+IAKG +V + +G
Sbjct 749 KVGELPP--NVQEIIAKGGLEKWVKNAIG 775
Score = 21.2 bits (43), Expect = 3.5
Identities = 22/85 (26%), Positives = 33/85 (39%), Gaps = 14/85 (16%)
Query 170 VFKVTGETNTDDLSPAQDAWSRPDIPLHANAMLKNERDGINPEKPGEVGPLSQIKELIAK 229
VF NTD + P + + + D+P A + E +PE AK
Sbjct 600 VFCDADNVNTDGIYPGKYTY-QDDVPPETMARVCMEN--YDPEF-----------STTAK 645
Query 230 GNQVAYVGDVVGTGSSRKSATNSVL 254
+ G G GSSR+ A ++L
Sbjct 646 EGDILVSGFNFGCGSSREQAATAIL 670
>Q44427 3-isopropylmalate dehydratase large subunit [Actinoplanes
teichomyceticus]
Length=485
Score = 94.0 bits (232), Expect = 5e-23
Identities = 108/404 (27%), Positives = 162/404 (40%), Gaps = 76/404 (19%)
Query 474 GVSLRP-GD---GIIHSWLNRMLL--PDTVGTGGDSHTRF---PIGISFPAGSGLVAFAA 524
GV +RP GD GI+H ++ L P GDSHT ++F G+ V
Sbjct 114 GVEIRPLGDVNQGIVHVIGPQLGLTQPGMTIVCGDSHTATHGASGALAFGIGTSEVEHVL 173
Query 525 ATGVMPLDMPESVLVKFKGKMQPGITLRDLVHAIPYYAIKEGDLTVEKKGKKNIFSGRIL 584
AT +P P+++ V G+++PG++ +DL+ + +T G N G I+
Sbjct 174 ATQTLPQSKPKTMAVTVVGELRPGVSAKDLILTL---------ITQTGTGGGN---GHIV 221
Query 585 EIDLTEMETDLTVEQAFELSDASAERSAAGCAITLSEEKVAEYLRSNITMLKWMISQGYG 644
E E L++E + + S E A I +E +YL
Sbjct 222 EYR-GEAIRKLSMEGRMTICNMSIEWGAKAGMIA-PDETTFDYL---------------- 263
Query 645 DARTMARRVENMEKWLANPSLLKADADAEYTKVYEIDLADIKEPILCCPND--------- 695
R ARR + + +A L D AEY +D + I I N
Sbjct 264 SGRKHARRGADWDAAVAYWKTLATDEGAEYDTEIILDASKISPFITWGTNPGQGAALDGV 323
Query 696 -PDDAKLLSDVQGDK--------------------IDEVFIGSCMTN-IGHFRAAGQLLE 733
PD L +V+ +D VF+GSC + RAA ++
Sbjct 324 VPDPQDFLDEVERGAAERALAYMGLTPGTPFRDVPVDVVFVGSCTNGRLEDLRAAADVIR 383
Query 734 --KVPSGSLTTRLWLAPPTRMDEHQLMEEGFYNTYGRAGARTEMPGCSLCMG-NQARVAP 790
KV G R+ + P + Q EG + AGA GCS+C+G N ++P
Sbjct 384 GRKVADG---VRMMIVPGSYQVREQAEAEGLDKIFIDAGAEWRFAGCSMCLGMNPDTLSP 440
Query 791 NTTVVSTSTRNFPNRLGQGSNVYLASAELASVAAVLGKLPTPEE 834
STS RNF R G+G +L S ++A+ AV+GKL P +
Sbjct 441 GQRAASTSNRNFEGRQGKGGRTHLVSPQVAAATAVVGKLAAPAD 484
Score = 21.6 bits (44), Expect = 2.5
Identities = 13/32 (41%), Positives = 15/32 (47%), Gaps = 1/32 (3%)
Query 351 VGRGLTTKAREALGLEPSTLFR-TPVQPAATG 381
V RG +A +GL P T FR PV G
Sbjct 334 VERGAAERALAYMGLTPGTPFRDVPVDVVFVG 365
>P17279 3-isopropylmalate dehydratase [Mucor circinelloides f.
lusitanicus]
Length=644
Score = 87.8 bits (216), Expect = 8e-21
Identities = 99/420 (24%), Positives = 169/420 (40%), Gaps = 73/420 (17%)
Query 493 LPDTVGTGGDSHTRFPIG---ISFPAGSGLVAFAAATGVMPLDMPESVLVKFKGKMQPGI 549
LP T GDSHT ++F G+ V AT + +++ ++ +GK PG+
Sbjct 172 LPATTVVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLLQKKSKNMRIRVQGKALPGV 231
Query 550 TLRDLV-HAIPYYAIKEGDLTVEKKGKKNIFSGRILEIDLTEMETDLTVEQAFELSDASA 608
T +D+V H I G +G ++E + L++E + + S
Sbjct 232 TSKDIVLHIIGVIGTAGG-------------TGCVIEF-CGDTIAALSMESRMSICNMSI 277
Query 609 ERSAAGCAITLSEEKVAEYLRSNITMLKWMISQGYGDARTMARRVENMEKWLANPSLLKA 668
E + A + +E EYLR + +A + + ++ + L +
Sbjct 278 E-AGARAGMVAPDEVTFEYLRD----------------KPLAPKGADWDRAVKYWKSLSS 320
Query 669 DADAEYTKVYEIDLADIKEPIL--CCPND--------PDDAKLLSDV------------- 705
DADA+Y EI+ ADI + P D PD AK+ +
Sbjct 321 DADAKYDINVEINAADIAPTLTWGTSPQDVVPITGSTPDPAKIEDPIRRSAVQRALDYIG 380
Query 706 -------QGDKIDEVFIGSCMTN-IGHFRAAGQLLEKVPSGSLTTRLWLAPPTRMDEHQL 757
+G K+D+VFIGSC + I RAA +++ + + + P + + + Q
Sbjct 381 IAPNTPMEGVKVDKVFIGSCTNSRIEDLRAAAAVVKGKRAAEWVDAM-VVPGSGLVKRQA 439
Query 758 MEEGFYNTYGRAGARTEMPGCSLCMG-NQARVAPNTTVVSTSTRNFPNRLGQGSNVYLAS 816
EG + AG GCS+C+G N ++ P STS RNF R G G +L S
Sbjct 440 EREGLDKIFTDAGFDWREAGCSMCLGMNPDQLKPGERCASTSNRNFEGRQGAGGRTHLVS 499
Query 817 AELASVAAVLGKLPTPEEYQQYAAQIDSMSADIYKYLNFDKMGEYTNAADQVDTKKIAAA 876
+A+ A + G L ++ + + + + E+ + D VD+ + +A
Sbjct 500 PAMAAAAGIKGCLTDVRN-----MEVSEIPGTPKQSPRQEVVAEFESEEDDVDSSSVDSA 554
>P55251 3-isopropylmalate dehydratase [Rhizomucor pusillus]
Length=755
Score = 87.0 bits (214), Expect = 2e-20
Identities = 114/451 (25%), Positives = 177/451 (39%), Gaps = 78/451 (17%)
Query 461 MQHTLPDFIMNRGGVSLRPGDGIIH--SWLNRMLLPDTVGTGGDSHTRFPIG---ISFPA 515
++H + +F + G+ GI+H LP GDSHT ++F
Sbjct 92 LEHNVKEFGLTYFGMD-DSRQGIVHVIGPEQGFTLPGCTVNCGDSHTSTHGAFGALAFGI 150
Query 516 GSGLVAFAAATGVMPLDMPESVLVKFKGKMQPGITLRDLV-HAIPYYAIKEGDLTVEKKG 574
G+ V AT + +++ VK GK+ PG+T +D+V H I G
Sbjct 151 GTSEVEHVLATQTLLQKKSKNMRVKVDGKLAPGVTSKDIVLHIIGVIGTAGG-------- 202
Query 575 KKNIFSGRILEIDLTEMETDLTVEQAFELSDASAERSAAGCAITLSEEKVAEYLRSNITM 634
+G ++E + E +++E + + S E A I +E EY+R
Sbjct 203 -----TGCVIEFCGSAFE-QMSMEARMSVCNMSIEAGARAGMIA-PDETTFEYIR----- 250
Query 635 LKWMISQGYGDARTMARRVENMEKWLANPSLLKADADAEYTKVYEIDLADIKEPILCCPN 694
G A T A + +E W + L++D DA+Y ID ADI P L
Sbjct 251 -------GRPLAPTGAEWDKAVEYWRS----LRSDPDAKYDVDVFIDAADIA-PTLTWGT 298
Query 695 DPDDAKLLSDVQGD-------------------------------KIDEVFIGSCMTN-I 722
P D ++ D KID+VFIGSC + I
Sbjct 299 SPQDVVAITGTTPDPSTVSDPIRRQAMERALDYIGLKPNTPMQEVKIDKVFIGSCTNSRI 358
Query 723 GHFRAAGQLLEKVPSGSLTTRLWLAPPTRMDEHQLMEEGFYNTYGRAGARTEMPGCSLCM 782
RAA + + + + P + + + Q +EG + AG GCS+C+
Sbjct 359 EDLRAAAAIAKGRHVADWVYAM-VVPGSGLVKKQAEQEGLDRIFKEAGFDWREAGCSMCL 417
Query 783 G-NQARVAPNTTVVSTSTRNFPNRLGQGSNVYLASAELASVAAVLGKLPTPEEYQQYAAQ 841
G N ++ P STS RNF R G G +L S +A+ AAV G + AQ
Sbjct 418 GMNPDQLKPGERCASTSNRNFEGRQGAGGRTHLMSPAMAAAAAVTGYFTDVRKLT--PAQ 475
Query 842 IDSMSADIYKYLNFD---KMGEYTNAADQVD 869
D ++ K + + + ++ AADQ D
Sbjct 476 QDRPASPTPKKIETELEPPVEDHAKAADQAD 506
Score = 23.5 bits (49), Expect = 0.68
Identities = 24/82 (29%), Positives = 32/82 (39%), Gaps = 20/82 (24%)
Query 237 GDVVGTGSSRKSATNSVLWFFGD-EIAHIPNKKDGGYCLGSKIAPIFFNTMEDAGALPVE 295
G G GSSR+ A W F D I I + A IFFN G LP+
Sbjct 604 GPNFGCGSSREHAP----WAFNDFGIRSI---------IAPSFADIFFNNCFKNGMLPIT 650
Query 296 IDVANMNMGDEIVLKIDHAAAK 317
+ D++ + +HA K
Sbjct 651 LP------QDKVEMLAEHAKQK 666
Lambda K H a alpha
0.316 0.134 0.389 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 7987620
Database: 0691a3acaf6eba9280ba911bba910796.SwissProt.fasta
Posted date: May 20, 2024 11:03 AM
Number of letters in database: 10,761
Number of sequences in database: 17
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
