Comparative Genomics

ACIAD2398 / SwissProt Alignments

BLASTP 2.12.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: 1554e2bf06f6c387152987705bb335e2.SwissProt.fasta
           15 sequences; 1,518 total letters



Query= ACIAD2398

Length=118
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

O32222 Copper-sensing transcriptional repressor CsoR [Bacillus su...  89.7    1e-28
O07434 Copper-sensing transcriptional repressor RicR [Mycobacteri...  79.7    1e-24
P9WP48 Copper-sensing transcriptional repressor CsoR [Mycobacteri...  73.2    7e-22
A1QQ42 Copper-sensing transcriptional repressor CsoR [Mycobacteri...  73.2    7e-22
A1KHA2 Copper-sensing transcriptional repressor CsoR [Mycobacteri...  73.2    7e-22
Q7U0Y5 Copper-sensing transcriptional repressor CsoR [Mycobacteri...  73.2    7e-22
P9WP49 Copper-sensing transcriptional repressor CsoR [Mycobacteri...  73.2    7e-22
A0PLB8 Copper-sensing transcriptional repressor CsoR [Mycobacteri...  72.8    1e-21
A1A836 Transcriptional repressor FrmR [Escherichia coli O1:K1 / A...  45.8    2e-11
A7ZX05 Transcriptional repressor FrmR [Escherichia coli O9:H4 (st...  45.8    2e-11
Q8X5J3 Transcriptional repressor FrmR [Escherichia coli O157:H7]      45.8    2e-11
A7ZIA5 Transcriptional repressor FrmR [Escherichia coli O139:H28 ...  45.8    2e-11
P0AAP3 Transcriptional repressor FrmR [Escherichia coli (strain K...  45.8    2e-11
P55757 Uncharacterized protein in bioA 5'region [Serratia marcesc...  43.9    9e-11
P54431 Uncharacterized protein YrkD [Bacillus subtilis (strain 168)]  34.3    2e-07


>O32222 Copper-sensing transcriptional repressor CsoR [Bacillus 
subtilis (strain 168)]
Length=101

 Score = 89.7 bits (221),  Expect = 1e-28
 Identities = 44/91 (48%), Positives = 57/91 (63%), Gaps = 0/91 (0%)

Query  25   HMSQKHVIQPDKKALLNRLSRIGGQVNGVAQMVENDRYCVDILTQISAIRSALDSVSTQL  84
            H +  H    +K  + NRL RI GQV G+  MVENDRYCVDIL QISA+++A+ +V+  L
Sbjct  7    HKTLNHKSSKEKDQITNRLKRIEGQVRGIQNMVENDRYCVDILVQISAVQAAMKNVALHL  66

Query  85   LNHHVQGCVRRAVVEDGGEEVIGELLMLIKK  115
            L  H   CV  A+    GE+ I ELL + KK
Sbjct  67   LEDHAHHCVADAIKSGDGEQAISELLDVFKK  97


>O07434 Copper-sensing transcriptional repressor RicR [Mycobacterium 
tuberculosis (strain ATCC 25618 / H37Rv)]
Length=96

 Score = 79.7 bits (195),  Expect = 1e-24
 Identities = 41/84 (49%), Positives = 54/84 (64%), Gaps = 1/84 (1%)

Query  26   MSQKHVIQPDKKALLNRLSRIGGQVNGVAQMVENDRYCVDILTQISAIRSALDSVSTQLL  85
            M+  H     K     RL R+ GQV G+A+M+E D+YC+D+LTQISA+ SAL SV+  LL
Sbjct  1    MTAAHGYTQQKDNYAKRLRRVEGQVRGIARMIEEDKYCIDVLTQISAVTSALRSVALNLL  60

Query  86   NHHVQGCVRRAVVEDGGEEVIGEL  109
            + H+  CV RAV E GG    G+L
Sbjct  61   DEHLSHCVTRAVAE-GGPGADGKL  83


>P9WP48 Copper-sensing transcriptional repressor CsoR [Mycobacterium 
tuberculosis (strain CDC 1551 / Oshkosh)]
Length=119

 Score = 73.2 bits (178),  Expect = 7e-22
 Identities = 31/79 (39%), Positives = 56/79 (71%), Gaps = 0/79 (0%)

Query  36   KKALLNRLSRIGGQVNGVAQMVENDRYCVDILTQISAIRSALDSVSTQLLNHHVQGCVRR  95
            K+A LNRL  + G ++G+ +M+E+D YCVD++ QISA++S+L+  +  +L++H++ C   
Sbjct  9    KRAALNRLKTVRGHLDGIVRMLESDAYCVDVMKQISAVQSSLERANRVMLHNHLETCFST  68

Query  96   AVVEDGGEEVIGELLMLIK  114
            AV++  G+  I EL+  +K
Sbjct  69   AVLDGHGQAAIEELIDAVK  87


>A1QQ42 Copper-sensing transcriptional repressor CsoR [Mycobacterium 
tuberculosis (strain F11)]
Length=119

 Score = 73.2 bits (178),  Expect = 7e-22
 Identities = 31/79 (39%), Positives = 56/79 (71%), Gaps = 0/79 (0%)

Query  36   KKALLNRLSRIGGQVNGVAQMVENDRYCVDILTQISAIRSALDSVSTQLLNHHVQGCVRR  95
            K+A LNRL  + G ++G+ +M+E+D YCVD++ QISA++S+L+  +  +L++H++ C   
Sbjct  9    KRAALNRLKTVRGHLDGIVRMLESDAYCVDVMKQISAVQSSLERANRVMLHNHLETCFST  68

Query  96   AVVEDGGEEVIGELLMLIK  114
            AV++  G+  I EL+  +K
Sbjct  69   AVLDGHGQAAIEELIDAVK  87


>A1KHA2 Copper-sensing transcriptional repressor CsoR [Mycobacterium 
bovis (strain BCG / Pasteur 1173P2)]
Length=119

 Score = 73.2 bits (178),  Expect = 7e-22
 Identities = 31/79 (39%), Positives = 56/79 (71%), Gaps = 0/79 (0%)

Query  36   KKALLNRLSRIGGQVNGVAQMVENDRYCVDILTQISAIRSALDSVSTQLLNHHVQGCVRR  95
            K+A LNRL  + G ++G+ +M+E+D YCVD++ QISA++S+L+  +  +L++H++ C   
Sbjct  9    KRAALNRLKTVRGHLDGIVRMLESDAYCVDVMKQISAVQSSLERANRVMLHNHLETCFST  68

Query  96   AVVEDGGEEVIGELLMLIK  114
            AV++  G+  I EL+  +K
Sbjct  69   AVLDGHGQAAIEELIDAVK  87


>Q7U0Y5 Copper-sensing transcriptional repressor CsoR [Mycobacterium 
bovis (strain ATCC BAA-935 / AF2122/97)]
Length=119

 Score = 73.2 bits (178),  Expect = 7e-22
 Identities = 31/79 (39%), Positives = 56/79 (71%), Gaps = 0/79 (0%)

Query  36   KKALLNRLSRIGGQVNGVAQMVENDRYCVDILTQISAIRSALDSVSTQLLNHHVQGCVRR  95
            K+A LNRL  + G ++G+ +M+E+D YCVD++ QISA++S+L+  +  +L++H++ C   
Sbjct  9    KRAALNRLKTVRGHLDGIVRMLESDAYCVDVMKQISAVQSSLERANRVMLHNHLETCFST  68

Query  96   AVVEDGGEEVIGELLMLIK  114
            AV++  G+  I EL+  +K
Sbjct  69   AVLDGHGQAAIEELIDAVK  87


>P9WP49 Copper-sensing transcriptional repressor CsoR [Mycobacterium 
tuberculosis (strain ATCC 25618 / H37Rv)]
Length=119

 Score = 73.2 bits (178),  Expect = 7e-22
 Identities = 31/79 (39%), Positives = 56/79 (71%), Gaps = 0/79 (0%)

Query  36   KKALLNRLSRIGGQVNGVAQMVENDRYCVDILTQISAIRSALDSVSTQLLNHHVQGCVRR  95
            K+A LNRL  + G ++G+ +M+E+D YCVD++ QISA++S+L+  +  +L++H++ C   
Sbjct  9    KRAALNRLKTVRGHLDGIVRMLESDAYCVDVMKQISAVQSSLERANRVMLHNHLETCFST  68

Query  96   AVVEDGGEEVIGELLMLIK  114
            AV++  G+  I EL+  +K
Sbjct  69   AVLDGHGQAAIEELIDAVK  87


>A0PLB8 Copper-sensing transcriptional repressor CsoR [Mycobacterium 
ulcerans (strain Agy99)]
Length=117

 Score = 72.8 bits (177),  Expect = 1e-21
 Identities = 31/85 (36%), Positives = 57/85 (67%), Gaps = 0/85 (0%)

Query  30   HVIQPDKKALLNRLSRIGGQVNGVAQMVENDRYCVDILTQISAIRSALDSVSTQLLNHHV  89
            H +   K+A LNRL    G ++G+ +M+E+D YCVD++ Q+SA++S+L+  +  +L++H+
Sbjct  3    HELTDKKRAALNRLKTARGHLDGIIRMLESDAYCVDVMKQLSAVQSSLERANRVMLHNHL  62

Query  90   QGCVRRAVVEDGGEEVIGELLMLIK  114
            + C   AV++  G+  I EL+  +K
Sbjct  63   ETCFSAAVLDGRGQAAIDELIDAVK  87


>A1A836 Transcriptional repressor FrmR [Escherichia coli O1:K1 
/ APEC]
Length=91

 Score = 45.8 bits (107),  Expect = 2e-11
 Identities = 20/56 (36%), Positives = 36/56 (64%), Gaps = 0/56 (0%)

Query  35  DKKALLNRLSRIGGQVNGVAQMVENDRYCVDILTQISAIRSALDSVSTQLLNHHVQ  90
           +KK +L R+ RI GQ++ + + +E D  C  IL QI+A+R A + +  ++L  H++
Sbjct  7   EKKKVLTRVRRIRGQIDALERSLEGDAECRAILQQIAAVRGAANGLMAEVLESHIR  62


>A7ZX05 Transcriptional repressor FrmR [Escherichia coli O9:H4 
(strain HS)]
Length=91

 Score = 45.8 bits (107),  Expect = 2e-11
 Identities = 20/56 (36%), Positives = 36/56 (64%), Gaps = 0/56 (0%)

Query  35  DKKALLNRLSRIGGQVNGVAQMVENDRYCVDILTQISAIRSALDSVSTQLLNHHVQ  90
           +KK +L R+ RI GQ++ + + +E D  C  IL QI+A+R A + +  ++L  H++
Sbjct  7   EKKKVLTRVRRIRGQIDALERSLEGDAECRAILQQIAAVRGAANGLMAEVLESHIR  62


>Q8X5J3 Transcriptional repressor FrmR [Escherichia coli O157:H7]
Length=91

 Score = 45.8 bits (107),  Expect = 2e-11
 Identities = 20/56 (36%), Positives = 36/56 (64%), Gaps = 0/56 (0%)

Query  35  DKKALLNRLSRIGGQVNGVAQMVENDRYCVDILTQISAIRSALDSVSTQLLNHHVQ  90
           +KK +L R+ RI GQ++ + + +E D  C  IL QI+A+R A + +  ++L  H++
Sbjct  7   EKKKVLTRVRRIRGQIDALERSLEGDAECRAILQQIAAVRGAANGLMAEVLESHIR  62


>A7ZIA5 Transcriptional repressor FrmR [Escherichia coli O139:H28 
(strain E24377A / ETEC)]
Length=91

 Score = 45.8 bits (107),  Expect = 2e-11
 Identities = 20/56 (36%), Positives = 36/56 (64%), Gaps = 0/56 (0%)

Query  35  DKKALLNRLSRIGGQVNGVAQMVENDRYCVDILTQISAIRSALDSVSTQLLNHHVQ  90
           +KK +L R+ RI GQ++ + + +E D  C  IL QI+A+R A + +  ++L  H++
Sbjct  7   EKKKVLTRVRRIRGQIDALERSLEGDAECRAILQQIAAVRGAANGLMAEVLESHIR  62


>P0AAP3 Transcriptional repressor FrmR [Escherichia coli (strain 
K12)]
Length=91

 Score = 45.8 bits (107),  Expect = 2e-11
 Identities = 20/56 (36%), Positives = 36/56 (64%), Gaps = 0/56 (0%)

Query  35  DKKALLNRLSRIGGQVNGVAQMVENDRYCVDILTQISAIRSALDSVSTQLLNHHVQ  90
           +KK +L R+ RI GQ++ + + +E D  C  IL QI+A+R A + +  ++L  H++
Sbjct  7   EKKKVLTRVRRIRGQIDALERSLEGDAECRAILQQIAAVRGAANGLMAEVLESHIR  62


>P55757 Uncharacterized protein in bioA 5'region [Serratia marcescens]
Length=91

 Score = 43.9 bits (102),  Expect = 9e-11
 Identities = 21/56 (38%), Positives = 35/56 (63%), Gaps = 0/56 (0%)

Query  35  DKKALLNRLSRIGGQVNGVAQMVENDRYCVDILTQISAIRSALDSVSTQLLNHHVQ  90
           D+K LL R+ RI GQ   + + +E+   C  +L QI+A+R A++ +  Q+L  HV+
Sbjct  7   DQKKLLARVRRIKGQAEALERALESGGECSAVLQQIAAVRGAVNGLMAQVLEGHVR  62


>P54431 Uncharacterized protein YrkD [Bacillus subtilis (strain 
168)]
Length=63

 Score = 34.3 bits (77),  Expect = 2e-07
 Identities = 16/63 (25%), Positives = 40/63 (63%), Gaps = 1/63 (2%)

Query  56   MVENDRYCVDILTQISAIRSALDSVSTQLLNHHVQGCVRRAVVE-DGGEEVIGELLMLIK  114
            M+E  + C +++TQ++A R+A+D     +++ +++ CVR ++ + +  + ++ E + L+ 
Sbjct  1    MMEQGKDCREVVTQLAASRNAIDRAMGLIVSTNLEHCVRESLEKGEDTQNLVKEAVDLLV  60

Query  115  KMR  117
            K R
Sbjct  61   KSR  63



Lambda      K        H        a         alpha
   0.322    0.137    0.393    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 98820


  Database: 1554e2bf06f6c387152987705bb335e2.SwissProt.fasta
    Posted date:  May 9, 2024  9:17 PM
  Number of letters in database: 1,518
  Number of sequences in database:  15



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40