BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 9bfe69a6e057d0568043e6a3cad047e8.SwissProt.fasta
14 sequences; 4,364 total letters
Query= ACIAD2500
Length=321
Score E
Sequences producing significant alignments: (Bits) Value
Q9HV27 Cyclic di-GMP phosphodiesterase PA4781 [Pseudomonas aerugi... 103 1e-28
Q9KSB1 Probable cyclic di-GMP phosphodiesterase VC_1348 [Vibrio c... 97.4 4e-26
B8GZM2 Diguanylate cyclase [Caulobacter vibrioides (strain NA1000... 92.4 2e-24
Q9A5I5 Diguanylate cyclase [Caulobacter vibrioides (strain ATCC 1... 92.4 2e-24
P54443 Uncharacterized transcriptional regulatory protein YrkP [B... 84.0 2e-22
P13792 Alkaline phosphatase synthesis transcriptional regulatory ... 84.0 2e-22
P42421 Transcriptional regulatory protein YxdJ [Bacillus subtilis... 79.7 7e-21
P37478 Transcriptional regulatory protein WalR [Bacillus subtilis... 78.6 2e-20
Q8X613 Transcriptional regulatory protein ZraR [Escherichia coli ... 80.9 2e-20
Q9CD68 Response regulator MprA [Mycobacterium leprae (strain TN)] 77.0 6e-20
P14375 Transcriptional regulatory protein ZraR [Escherichia coli ... 79.3 7e-20
P08368 Transcriptional regulatory protein CreB [Escherichia coli ... 76.6 9e-20
P43501 Protein PilH [Pseudomonas aeruginosa (strain ATCC 15692 / ... 73.6 1e-19
Q02540 Transcriptional activator protein CopR [Pseudomonas syring... 75.5 2e-19
>Q9HV27 Cyclic di-GMP phosphodiesterase PA4781 [Pseudomonas aeruginosa
(strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847
/ LMG 12228 / 1C / PRS 101 / PAO1)]
Length=393
Score = 103 bits (258), Expect = 1e-28
Identities = 57/138 (41%), Positives = 89/138 (64%), Gaps = 5/138 (4%)
Query 15 DQAAILIVDDVPENLGLLHESLDQAGYRVLVTTDGLSAIEIA-HRCLPDMILLDGNMPHM 73
+Q +L+VDD P+NL L+ E L++ YRV G + + A PD+ILLD NMP M
Sbjct 9 EQELVLVVDDTPDNLLLMRELLEEQ-YRVRTAGSGPAGLRAAVEEPRPDLILLDVNMPGM 67
Query 74 DGFESCLQLKASPITQLIPVIFMTGLSETEHIVKGFQVGGVDYVTKPLNIEEVLARVKTH 133
DG+E C +LKA P+T+ IP++F+T ++ + +G +G VDY+ KP++ VLARV+TH
Sbjct 68 DGYEVCRRLKADPLTRDIPLMFLTARADRDDEQQGLALGAVDYLGKPVSPPIVLARVRTH 127
Query 134 L---AHAKLLQQQKQVID 148
L A+A L+ + + ++
Sbjct 128 LQLKANADFLRDKSEYLE 145
>Q9KSB1 Probable cyclic di-GMP phosphodiesterase VC_1348 [Vibrio
cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)]
Length=441
Score = 97.4 bits (241), Expect = 4e-26
Identities = 54/123 (44%), Positives = 76/123 (62%), Gaps = 1/123 (1%)
Query 16 QAAILIVDDVPENLGLLHESLDQAGYRVLVTTDGLSAIEIAHRCLPDMILLDGNMPHMDG 75
Q ILIVDD P+N+ + + L Q YR+ G A+EI + D++LLD MP M G
Sbjct 70 QCTILIVDDSPDNIAFMSQGLAQY-YRIKAARSGKVALEILAQYPIDLVLLDIVMPEMSG 128
Query 76 FESCLQLKASPITQLIPVIFMTGLSETEHIVKGFQVGGVDYVTKPLNIEEVLARVKTHLA 135
+E Q+K +P T+ IPVIF+TG S E GF++G VDYV KP++I + +RV THL
Sbjct 129 YEVINQIKHNPHTEHIPVIFLTGKSNPEDEQLGFELGAVDYVFKPVSIPLLKSRVHTHLQ 188
Query 136 HAK 138
+ +
Sbjct 189 NKR 191
Score = 18.1 bits (35), Expect = 4.0
Identities = 7/10 (70%), Positives = 8/10 (80%), Gaps = 0/10 (0%)
Query 180 DQSGFKLGLK 189
D SG+ LGLK
Sbjct 345 DGSGYPLGLK 354
Score = 17.3 bits (33), Expect = 7.0
Identities = 5/12 (42%), Positives = 10/12 (83%), Gaps = 0/12 (0%)
Query 11 PISHDQAAILIV 22
P+SH++A +I+
Sbjct 383 PMSHEEAKAIIL 394
>B8GZM2 Diguanylate cyclase [Caulobacter vibrioides (strain NA1000
/ CB15N)]
Length=454
Score = 92.4 bits (228), Expect = 2e-24
Identities = 50/129 (39%), Positives = 75/129 (58%), Gaps = 0/129 (0%)
Query 17 AAILIVDDVPENLGLLHESLDQAGYRVLVTTDGLSAIEIAHRCLPDMILLDGNMPHMDGF 76
A IL+VDD+ N+ LL L Y V DG +A+ +A R LPD+ILLD MP MDGF
Sbjct 3 ARILVVDDIEANVRLLEAKLTAEYYEVSTAMDGPTALAMAARDLPDIILLDVMMPGMDGF 62
Query 77 ESCLQLKASPITQLIPVIFMTGLSETEHIVKGFQVGGVDYVTKPLNIEEVLARVKTHLAH 136
C +LK P T+ IPV+ +T L ++G + G D++TKP++ + ARV++
Sbjct 63 TVCRKLKDDPTTRHIPVVLITALDGRGDRIQGLESGASDFLTKPIDDVMLFARVRSLTRF 122
Query 137 AKLLQQQKQ 145
++ + +Q
Sbjct 123 KLVIDELRQ 131
Score = 45.4 bits (106), Expect = 9e-09
Identities = 35/144 (24%), Positives = 71/144 (49%), Gaps = 17/144 (12%)
Query 19 ILIVDD-------VPENLGLLHESLDQAGYRVLVTTDGLSAIEIAHRCLPDMILLDGNMP 71
+LIVDD V LG+ H R ++ +D A +I+ D+++++
Sbjct 156 VLIVDDNERQAQRVAAELGVEH--------RPVIESDPEKA-KISAGGPVDLVIVNAAAK 206
Query 72 HMDGFESCLQLKASPITQLIPVIFMTGLSETEHIVKGFQVGGVDYVTKPLNIEEVLARVK 131
+ DG L++ T+ +PV+ M + +VK ++G D +++P++ +E+ ARVK
Sbjct 207 NFDGLRFTAALRSEERTRQLPVLAMVDPDDRGRMVKALEIGVNDILSRPIDPQELSARVK 266
Query 132 THLAHAKLLQQQKQVID-ATEVAI 154
T + + + +D + E+A+
Sbjct 267 TQIQRKRYTDYLRNNLDHSLELAV 290
>Q9A5I5 Diguanylate cyclase [Caulobacter vibrioides (strain ATCC
19089 / CB15)]
Length=454
Score = 92.4 bits (228), Expect = 2e-24
Identities = 50/129 (39%), Positives = 75/129 (58%), Gaps = 0/129 (0%)
Query 17 AAILIVDDVPENLGLLHESLDQAGYRVLVTTDGLSAIEIAHRCLPDMILLDGNMPHMDGF 76
A IL+VDD+ N+ LL L Y V DG +A+ +A R LPD+ILLD MP MDGF
Sbjct 3 ARILVVDDIEANVRLLEAKLTAEYYEVSTAMDGPTALAMAARDLPDIILLDVMMPGMDGF 62
Query 77 ESCLQLKASPITQLIPVIFMTGLSETEHIVKGFQVGGVDYVTKPLNIEEVLARVKTHLAH 136
C +LK P T+ IPV+ +T L ++G + G D++TKP++ + ARV++
Sbjct 63 TVCRKLKDDPTTRHIPVVLITALDGRGDRIQGLESGASDFLTKPIDDVMLFARVRSLTRF 122
Query 137 AKLLQQQKQ 145
++ + +Q
Sbjct 123 KLVIDELRQ 131
Score = 45.4 bits (106), Expect = 9e-09
Identities = 35/144 (24%), Positives = 71/144 (49%), Gaps = 17/144 (12%)
Query 19 ILIVDD-------VPENLGLLHESLDQAGYRVLVTTDGLSAIEIAHRCLPDMILLDGNMP 71
+LIVDD V LG+ H R ++ +D A +I+ D+++++
Sbjct 156 VLIVDDNERQAQRVAAELGVEH--------RPVIESDPEKA-KISAGGPVDLVIVNAAAK 206
Query 72 HMDGFESCLQLKASPITQLIPVIFMTGLSETEHIVKGFQVGGVDYVTKPLNIEEVLARVK 131
+ DG L++ T+ +PV+ M + +VK ++G D +++P++ +E+ ARVK
Sbjct 207 NFDGLRFTAALRSEERTRQLPVLAMVDPDDRGRMVKALEIGVNDILSRPIDPQELSARVK 266
Query 132 THLAHAKLLQQQKQVID-ATEVAI 154
T + + + +D + E+A+
Sbjct 267 TQIQRKRYTDYLRNNLDHSLELAV 290
>P54443 Uncharacterized transcriptional regulatory protein YrkP
[Bacillus subtilis (strain 168)]
Length=231
Score = 84.0 bits (206), Expect = 2e-22
Identities = 48/127 (38%), Positives = 75/127 (59%), Gaps = 4/127 (3%)
Query 19 ILIVDDVPENLGLLHESLDQAGYRVLVTTDGLSAIEIAHRCLPDMILLDGNMPHMDGFES 78
IL+V+D + LL ESL +AGY VL DG A+++ + L D+++LD MP + G E+
Sbjct 5 ILVVEDDEDIGDLLEESLTRAGYEVLRAKDGKRALQLVNDSL-DLVILDIMMPGISGIET 63
Query 79 CLQLKASPITQLIPVIFMTGLSETEHIVKGFQVGGVDYVTKPLNIEEVLARVKTHLAHAK 138
C ++ S +P++F+T S T +G GG DY+TKP + EE+ ARV L
Sbjct 64 CQHIRKS---SNVPILFLTARSSTLDKTEGLLAGGDDYMTKPFSEEELHARVIAQLRRYT 120
Query 139 LLQQQKQ 145
+ Q++K+
Sbjct 121 IYQEKKE 127
>P13792 Alkaline phosphatase synthesis transcriptional regulatory
protein PhoP [Bacillus subtilis (strain 168)]
Length=240
Score = 84.0 bits (206), Expect = 2e-22
Identities = 49/143 (34%), Positives = 81/143 (57%), Gaps = 3/143 (2%)
Query 19 ILIVDDVPENLGLLHESLDQAGYRVLVTTDGLSAIEIAHRCLPDMILLDGNMPHMDGFES 78
IL+VDD + LL +L+++GY V+ +DG A++ A PD+I+LD +P +DG E
Sbjct 5 ILVVDDEESIVTLLQYNLERSGYDVITASDGEEALKKAETEKPDLIVLDVMLPKLDGIEV 64
Query 79 CLQLKASPITQLIPVIFMTGLSETEHIVKGFQVGGVDYVTKPLNIEEVLARVKTHLAHAK 138
C QL+ + + P++ +T E V G ++G DY+TKP + EV ARVK L ++
Sbjct 65 CKQLRQQKL--MFPILMLTAKDEEFDKVLGLELGADDYMTKPFSPREVNARVKAILRRSE 122
Query 139 LLQQQKQV-IDATEVAIIALDIQ 160
+ ++ D E I+ D++
Sbjct 123 IAAPSSEMKNDEMEGQIVIGDLK 145
>P42421 Transcriptional regulatory protein YxdJ [Bacillus subtilis
(strain 168)]
Length=229
Score = 79.7 bits (195), Expect = 7e-21
Identities = 49/155 (32%), Positives = 85/155 (55%), Gaps = 4/155 (3%)
Query 19 ILIVDDVPENLGLLHESLDQAGYRVLVTTDGLSAIEIAHRCLPDMILLDGNMPHMDGFES 78
I+IV+D + GLL L++ GY+ +V D + +++ R PD++LLD N+P DG+
Sbjct 4 IMIVEDSEDIRGLLQNYLEKYGYQTVVAADFTAVLDVFLREKPDVVLLDINLPAYDGYYW 63
Query 79 CLQLKASPITQLIPVIFMTGLSETEHIVKGFQVGGVDYVTKPLNIEEVLARVKTHLAHAK 138
C Q++ + P+IF++ S V + GG DY+ KP + + VLA++K+ + A
Sbjct 64 CRQIRQHSTS---PIIFISARSGEMDQVMAIENGGDDYIEKPFSYDIVLAKIKSQIRRAY 120
Query 139 LLQQQKQVIDATEVAIIALDIQG-EMAWQTDKATL 172
KQ E A + L ++ E+ +Q +K+ L
Sbjct 121 GEYAAKQGEKVVEYAGVQLFVERFELRFQDEKSEL 155
>P37478 Transcriptional regulatory protein WalR [Bacillus subtilis
(strain 168)]
Length=235
Score = 78.6 bits (192), Expect = 2e-20
Identities = 48/141 (34%), Positives = 73/141 (52%), Gaps = 3/141 (2%)
Query 19 ILIVDDVPENLGLLHESLDQAGYRVLVTTDGLSAIEIAHRCLPDMILLDGNMPHMDGFES 78
IL+VDD +L +L + GY V DG A+E+ PD+ILLD +P+ DG E
Sbjct 5 ILVVDDEKPIADILEFNLRKEGYEVHCAHDGNEAVEMVEELQPDLILLDIMLPNKDGVEV 64
Query 79 CLQLKASPITQLIPVIFMTGLSETEHIVKGFQVGGVDYVTKPLNIEEVLARVKTHLAHAK 138
C +++ +P+I +T V G ++G DYVTKP + E+LARVK +L
Sbjct 65 CREVRKK---YDMPIIMLTAKDSEIDKVIGLEIGADDYVTKPFSTRELLARVKANLRRQL 121
Query 139 LLQQQKQVIDATEVAIIALDI 159
++ + E+ I +L I
Sbjct 122 TTAPAEEEPSSNEIHIGSLVI 142
Score = 20.4 bits (41), Expect = 0.68
Identities = 8/14 (57%), Positives = 11/14 (79%), Gaps = 0/14 (0%)
Query 256 QLTQREAEVSHWLA 269
+LT RE E+ H+LA
Sbjct 157 ELTHREFELLHYLA 170
>Q8X613 Transcriptional regulatory protein ZraR [Escherichia coli
O157:H7]
Length=441
Score = 80.9 bits (198), Expect = 2e-20
Identities = 43/144 (30%), Positives = 75/144 (52%), Gaps = 2/144 (1%)
Query 12 ISHDQAAILIVDDVPENLGLLHESLDQAGYRVLVTTDGLSAIEIAHRCLPDMILLDGNMP 71
++HD IL+VDD + +L L GY V + G A+E + D++L D M
Sbjct 1 MTHDNIDILVVDDDISHCTILQALLRGWGYNVALANSGRQALEQVRERVFDLVLCDVRMA 60
Query 72 HMDGFESCLQLKASPITQLIPVIFMTGLSETEHIVKGFQVGGVDYVTKPLNIEEVLARVK 131
MDG + ++KA + IPV+ MT S E V+ + G +DY+ KPL+ + + A ++
Sbjct 61 EMDGIATLKEIKA--LNPAIPVLIMTAYSSVETAVEALKTGALDYLIKPLDFDNLQATLE 118
Query 132 THLAHAKLLQQQKQVIDATEVAII 155
LAH ++ + + A++ ++
Sbjct 119 KALAHTHIIDAETPAVTASQFGMV 142
>Q9CD68 Response regulator MprA [Mycobacterium leprae (strain
TN)]
Length=228
Score = 77.0 bits (188), Expect = 6e-20
Identities = 44/120 (37%), Positives = 63/120 (53%), Gaps = 2/120 (2%)
Query 19 ILIVDDVPENLGLLHESLDQAGYRVLVTTDGLSAIEIAHRCLPDMILLDGNMPHMDGFES 78
IL VDD L SL GY V + DG+ A+E+ R PD ++LD MP +DG E
Sbjct 3 ILAVDDDRAVRESLRRSLSFNGYSVELANDGVEALEMVARDRPDALVLDVMMPRLDGLEV 62
Query 79 CLQLKASPITQLIPVIFMTGLSETEHIVKGFQVGGVDYVTKPLNIEEVLARVKTHLAHAK 138
C QL+++ +P++ +T V G G DY+ KP +EE+LAR++ L K
Sbjct 63 CRQLRST--GDDLPILVLTARDSVSERVAGLDAGADDYLPKPFALEELLARIRALLRRTK 120
Score = 24.6 bits (52), Expect = 0.029
Identities = 14/47 (30%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query 242 STALSIEDILKYCPQLTQREAEVSHWLALGKTNKDIAEILELSPRTV 288
S A+S D+ +T+ A W++L +T + E+L +PR V
Sbjct 127 SVAMSFSDLT--LDPVTREVARGQRWISLTRTEFALLEMLIANPRRV 171
>P14375 Transcriptional regulatory protein ZraR [Escherichia coli
(strain K12)]
Length=441
Score = 79.3 bits (194), Expect = 7e-20
Identities = 43/144 (30%), Positives = 74/144 (51%), Gaps = 2/144 (1%)
Query 12 ISHDQAAILIVDDVPENLGLLHESLDQAGYRVLVTTDGLSAIEIAHRCLPDMILLDGNMP 71
++HD IL+VDD + +L L GY V + G A+E + D++L D M
Sbjct 1 MTHDNIDILVVDDDISHCTILQALLRGWGYNVALANSGRQALEQVREQVFDLVLCDVRMA 60
Query 72 HMDGFESCLQLKASPITQLIPVIFMTGLSETEHIVKGFQVGGVDYVTKPLNIEEVLARVK 131
MDG + ++KA + IPV+ MT S E V+ + G +DY+ KPL+ + + A ++
Sbjct 61 EMDGIATLKEIKA--LNPAIPVLIMTAYSSVETAVEALKTGALDYLIKPLDFDNLQATLE 118
Query 132 THLAHAKLLQQQKQVIDATEVAII 155
LAH + + + A++ ++
Sbjct 119 KALAHTHSIDAETPAVTASQFGMV 142
>P08368 Transcriptional regulatory protein CreB [Escherichia coli
(strain K12)]
Length=229
Score = 76.6 bits (187), Expect = 9e-20
Identities = 46/129 (36%), Positives = 68/129 (53%), Gaps = 2/129 (2%)
Query 19 ILIVDDVPENLGLLHESLDQAGYRVLVTTDGLSAIEIAHRCLPDMILLDGNMPHMDGFES 78
+ +V+D L L Q G+ V V GL ++ A + +PD+++LD +P + GFE
Sbjct 6 VWLVEDEQGIADTLVYMLQQEGFAVEVFERGLPVLDKARKQVPDVMILDVGLPDISGFEL 65
Query 79 CLQLKASPITQLIPVIFMTGLSETEHIVKGFQVGGVDYVTKPLNIEEVLARVKTHLAHAK 138
C QL A + +PV+F+T SE + G ++G DYV KP + EV ARV+T L K
Sbjct 66 CRQLLA--LHPALPVLFLTARSEEVDRLLGLEIGADDYVAKPFSPREVCARVRTLLRRVK 123
Query 139 LLQQQKQVI 147
VI
Sbjct 124 KFSTPSPVI 132
>P43501 Protein PilH [Pseudomonas aeruginosa (strain ATCC 15692
/ DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS
101 / PAO1)]
Length=121
Score = 73.6 bits (179), Expect = 1e-19
Identities = 43/119 (36%), Positives = 67/119 (56%), Gaps = 0/119 (0%)
Query 17 AAILIVDDVPENLGLLHESLDQAGYRVLVTTDGLSAIEIAHRCLPDMILLDGNMPHMDGF 76
A ILIVDD P + L L++ G++VL +G + +A + PD++L+D MP ++GF
Sbjct 2 ARILIVDDSPTEMYKLTAMLEKHGHQVLKAENGGDGVALARQEKPDVVLMDIVMPGLNGF 61
Query 77 ESCLQLKASPITQLIPVIFMTGLSETEHIVKGFQVGGVDYVTKPLNIEEVLARVKTHLA 135
++ QL T IPVI +T + V G + G DY+TKP++ E +L + LA
Sbjct 62 QATRQLTKDAETSAIPVIIVTTKDQETDKVWGKRQGARDYLTKPVDEETLLKTINAVLA 120
>Q02540 Transcriptional activator protein CopR [Pseudomonas syringae
pv. tomato]
Length=227
Score = 75.5 bits (184), Expect = 2e-19
Identities = 43/125 (34%), Positives = 70/125 (56%), Gaps = 2/125 (2%)
Query 19 ILIVDDVPENLGLLHESLDQAGYRVLVTTDGLSAIEIAHRCLPDMILLDGNMPHMDGFES 78
+L+ +D P+ L + L +AG+ V G A++ A D+++LD MP +DG+E
Sbjct 3 LLVAEDEPKTGIYLQQGLREAGFNVDRVVTGTDAVDQALNEAYDLLILDVMMPGLDGWEV 62
Query 79 CLQLKASPITQLIPVIFMTGLSETEHIVKGFQVGGVDYVTKPLNIEEVLARVKTHLAHAK 138
+L+ + Q +PV+F+T + VKG ++G DY+ KP + E+LARV+T L
Sbjct 63 IRRLRTAG--QPVPVLFLTARDGVDDRVKGLELGADDYLVKPFALSELLARVRTLLRRGS 120
Query 139 LLQQQ 143
LQ Q
Sbjct 121 SLQVQ 125
Lambda K H a alpha
0.321 0.134 0.390 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1030584
Database: 9bfe69a6e057d0568043e6a3cad047e8.SwissProt.fasta
Posted date: May 9, 2024 6:18 PM
Number of letters in database: 4,364
Number of sequences in database: 14
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
