BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: d083b41a74de0ec8bdd58c2017f0e73b.SwissProt.fasta
14 sequences; 5,561 total letters
Query= ACIAD2516
Length=395
Score E
Sequences producing significant alignments: (Bits) Value
Q9ZHI1 Acetyl-CoA acetyltransferase [Chromobacterium violaceum (s... 367 5e-129
Q9I2A8 Acetyl-CoA acetyltransferase [Pseudomonas aeruginosa (stra... 364 9e-128
P14611 Acetyl-CoA acetyltransferase [Cupriavidus necator (strain ... 355 5e-124
P45359 Acetyl-CoA acetyltransferase [Clostridium acetobutylicum (... 348 2e-121
Q04677 Acetyl-CoA acetyltransferase IB [Candida tropicalis] 347 8e-121
P76461 Acetyl-CoA acetyltransferase [Escherichia coli (strain K12)] 345 2e-120
Q9UQW6 Acetyl-CoA acetyltransferase [Schizosaccharomyces pombe (s... 345 5e-120
Q12598 Acetyl-CoA acetyltransferase IA [Candida tropicalis] 344 9e-120
P44873 Acetyl-CoA acetyltransferase [Haemophilus influenzae (stra... 343 1e-119
Q86AD9 Probable acetyl-CoA acetyltransferase [Dictyostelium disco... 338 3e-117
Q6L8K7 Acetyl-CoA acetyltransferase [Yarrowia lipolytica (strain ... 337 5e-117
Q0AVM3 Acetyl-CoA acetyltransferase [Syntrophomonas wolfei subsp.... 337 8e-117
A0A1D8PH52 Acetyl-CoA acetyltransferase [Candida albicans (strain... 336 2e-116
P45369 Acetyl-CoA acetyltransferase [Allochromatium vinosum (stra... 335 4e-116
>Q9ZHI1 Acetyl-CoA acetyltransferase [Chromobacterium violaceum
(strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB
9131 / NCTC 9757)]
Length=392
Score = 367 bits (943), Expect = 5e-129
Identities = 198/389 (51%), Positives = 259/389 (67%), Gaps = 2/389 (1%)
Query 5 KIMIAAAARTPMGSFQGSLAGLTAPDLGAVVIQRVLEQTQIPAADIDEVIMGCVLPAGLK 64
++ I AA RT +GSF G LA + AP+LGA VI+ +LE+T + D+ EVI+G VL AG
Sbjct 2 EVAIVAAQRTAIGSFGGGLAKIPAPELGATVIKALLEKTGVKPEDVSEVILGQVLTAGSG 61
Query 65 QAPARQAMRQAGLPDHVGATTINKVCGSGMKATMFAADAILAGSIQIAVVGGMESMTNSP 124
Q PARQA+ +AGLP ATT+N VCGSG++A AA AILAG I + GG ESM+ SP
Sbjct 62 QNPARQALIKAGLPVTTPATTLNVVCGSGLRAVHLAAQAILAGDADIVIAGGQESMSLSP 121
Query 125 YLLPKARSGYRMGHGQVLDHMFLDGLEDAYTGRAMGSFAQDMANQKGYTREQMDAFAIRS 184
++LP +R G+RMG+ Q++D M DGL DAY MG A+++A + G RE+ DAF+++S
Sbjct 122 HILPGSRDGFRMGNAQLVDTMVNDGLTDAYNAYHMGITAENVAAKYGIGREEQDAFSLQS 181
Query 185 LTRAQHAITAGHFQSEIAPVTVATRKGD-ITVSEDE-NPGNAKIDKIPSLRPAFAKDGTI 242
RA A AG F+ EI PV V RKGD + DE +A D + LRPAF KDGT+
Sbjct 182 QQRAAAAQKAGKFRDEIVPVLVPQRKGDPLAFDADEFIKHDASADGLAKLRPAFKKDGTV 241
Query 243 TAANSSSISDGASALLITSEQQAEQRGLKVLAEIKGYTTHSQLPAEFTIAPVGAIEKLLK 302
TA N+S I+DGA+A+L+ S Q+A+Q GLK LA IKGY P I PV A K L
Sbjct 242 TAGNASGINDGAAAVLLMSTQKADQLGLKPLAIIKGYALTGCEPEIMGIGPVSATRKALS 301
Query 303 KIGWTAEEVDLWEINEAFAMVTMAAIDAFKLDAEKVNINGGACALGHPLGSSGSRIIVTL 362
K GWT E++DL E NEAFA + ++KVN+NGGA ALGHP+G+SG R++VTL
Sbjct 302 KAGWTVEDLDLVEANEAFAAQALGVAKELGWGSDKVNVNGGAIALGHPIGASGCRVLVTL 361
Query 363 IHALKRLGKRKGIAALCIGGGEATALAIE 391
+H ++R G +KG+A LCIGGG ALA+E
Sbjct 362 LHEMQRRGAKKGLATLCIGGGMGVALAVE 390
>Q9I2A8 Acetyl-CoA acetyltransferase [Pseudomonas aeruginosa (strain
ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG
12228 / 1C / PRS 101 / PAO1)]
Length=393
Score = 364 bits (935), Expect = 9e-128
Identities = 192/390 (49%), Positives = 260/390 (67%), Gaps = 2/390 (1%)
Query 3 MSKIMIAAAARTPMGSFQGSLAGLTAPDLGAVVIQRVLEQTQIPAADIDEVIMGCVLPAG 62
M ++I AA RT +GSFQGSLAG+ AP+LGA VI+R+LEQT + A +DEVI+G VL AG
Sbjct 1 MQDVVIVAATRTAVGSFQGSLAGIPAPELGAAVIRRLLEQTGLDAGQVDEVILGQVLTAG 60
Query 63 LKQAPARQAMRQAGLPDHVGATTINKVCGSGMKATMFAADAILAGSIQIAVVGGMESMTN 122
Q PARQA +AGLP V A T+NKVCGSG+KA A AI G ++ V GG E+M+
Sbjct 61 SGQNPARQAAIKAGLPVGVPAMTLNKVCGSGLKALHLGAQAIRCGDAEVIVAGGQENMSL 120
Query 123 SPYLLPKARSGYRMGHGQVLDHMFLDGLEDAYTGRAMGSFAQDMANQKGYTREQMDAFAI 182
+PY++P AR+G RMGH +++D M DGL DA+ MG A+++A + G TRE+ DAFA
Sbjct 121 APYVMPGARTGLRMGHAKLVDSMIEDGLWDAFNDYHMGITAENLAEKYGLTREEQDAFAA 180
Query 183 RSLTRAQHAITAGHFQSEIAPVTVATRKGD-ITVSEDENP-GNAKIDKIPSLRPAFAKDG 240
S +A AI G F+ EI P+ V RKG+ + DE P ++ + L+PAF KDG
Sbjct 181 ASQQKAIAAIEGGRFRDEITPIQVPQRKGEPLGFDTDEQPRAGTTVEALAKLKPAFRKDG 240
Query 241 TITAANSSSISDGASALLITSEQQAEQRGLKVLAEIKGYTTHSQLPAEFTIAPVGAIEKL 300
++TA N+SS++DGA+A+L+ S +A+ GL VLA I Y + PA I PV A +
Sbjct 241 SVTAGNASSLNDGAAAVLLMSAAKAKALGLPVLARIASYASAGVDPAIMGIGPVSATRRA 300
Query 301 LKKIGWTAEEVDLWEINEAFAMVTMAAIDAFKLDAEKVNINGGACALGHPLGSSGSRIIV 360
L K GW+ E++DL E NEAFA ++A DA +VN+NGGA ALGHP+G+SG R++V
Sbjct 301 LDKAGWSLEQLDLIEANEAFAAQSLAVGRELGWDAARVNVNGGAIALGHPIGASGCRVLV 360
Query 361 TLIHALKRLGKRKGIAALCIGGGEATALAI 390
TL+H + R +KG+A LCIGGG+ AL +
Sbjct 361 TLLHEMIRRDAKKGLATLCIGGGQGVALTL 390
>P14611 Acetyl-CoA acetyltransferase [Cupriavidus necator (strain
ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 /
Stanier 337)]
Length=393
Score = 355 bits (910), Expect = 5e-124
Identities = 189/391 (48%), Positives = 258/391 (66%), Gaps = 2/391 (1%)
Query 3 MSKIMIAAAARTPMGSFQGSLAGLTAPDLGAVVIQRVLEQTQIPAADIDEVIMGCVLPAG 62
M+ ++I +AART +G F GSLA + AP+LGAVVI+ LE+ + + EVIMG VL AG
Sbjct 1 MTDVVIVSAARTAVGKFGGSLAKIPAPELGAVVIKAALERAGVKPEQVSEVIMGQVLTAG 60
Query 63 LKQAPARQAMRQAGLPDHVGATTINKVCGSGMKATMFAADAILAGSIQIAVVGGMESMTN 122
Q PARQA +AGLP V A TINKVCGSG+KA M AA+AI+AG +I V GG E+M+
Sbjct 61 SGQNPARQAAIKAGLPAMVPAMTINKVCGSGLKAVMLAANAIMAGDAEIVVAGGQENMSA 120
Query 123 SPYLLPKARSGYRMGHGQVLDHMFLDGLEDAYTGRAMGSFAQDMANQKGYTREQMDAFAI 182
+P++LP +R G+RMG +++D M +DGL D Y MG A+++A + G TRE D FA+
Sbjct 121 APHVLPGSRDGFRMGDAKLVDTMIVDGLWDVYNQYHMGITAENVAKEYGITREAQDEFAV 180
Query 183 RSLTRAQHAITAGHFQSEIAPVTVATRKGD-ITVSEDE-NPGNAKIDKIPSLRPAFAKDG 240
S +A+ A AG F EI PV + RKGD + DE A +D + L+PAF K G
Sbjct 181 GSQNKAEAAQKAGKFDEEIVPVLIPQRKGDPVAFKTDEFVRQGATLDSMSGLKPAFDKAG 240
Query 241 TITAANSSSISDGASALLITSEQQAEQRGLKVLAEIKGYTTHSQLPAEFTIAPVGAIEKL 300
T+TAAN+S ++DGA+A+++ S +A++ GL LA IK Y P + PV A ++
Sbjct 241 TVTAANASGLNDGAAAVVVMSAAKAKELGLTPLATIKSYANAGVDPKVMGMGPVPASKRA 300
Query 301 LKKIGWTAEEVDLWEINEAFAMVTMAAIDAFKLDAEKVNINGGACALGHPLGSSGSRIIV 360
L + WT +++DL EINEAFA +A D KVN+NGGA A+GHP+G+SG RI+V
Sbjct 301 LSRAEWTPQDLDLMEINEAFAAQALAVHQQMGWDTSKVNVNGGAIAIGHPIGASGCRILV 360
Query 361 TLIHALKRLGKRKGIAALCIGGGEATALAIE 391
TL+H +KR +KG+A+LCIGGG ALA+E
Sbjct 361 TLLHEMKRRDAKKGLASLCIGGGMGVALAVE 391
>P45359 Acetyl-CoA acetyltransferase [Clostridium acetobutylicum
(strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)]
Length=392
Score = 348 bits (893), Expect = 2e-121
Identities = 179/390 (46%), Positives = 258/390 (66%), Gaps = 1/390 (0%)
Query 3 MSKIMIAAAARTPMGSFQGSLAGLTAPDLGAVVIQRVLEQTQIPAADIDEVIMGCVLPAG 62
M +++IA+A RT +GS+ SL + A DLGA I+ +++ I D++EVI+G VL AG
Sbjct 1 MKEVVIASAVRTAIGSYGKSLKDVPAVDLGATAIKEAVKKAGIKPEDVNEVILGNVLQAG 60
Query 63 LKQAPARQAMRQAGLPDHVGATTINKVCGSGMKATMFAADAILAGSIQIAVVGGMESMTN 122
L Q PARQA +AGLP + A TINKVCGSG++ AA I AG + + GGME+M+
Sbjct 61 LGQNPARQASFKAGLPVEIPAMTINKVCGSGLRTVSLAAQIIKAGDADVIIAGGMENMSR 120
Query 123 SPYLLPKARSGYRMGHGQVLDHMFLDGLEDAYTGRAMGSFAQDMANQKGYTREQMDAFAI 182
+PYL AR GYRMG+ + +D M DGL DA+ MG A+++A + +RE+ D FA+
Sbjct 121 APYLANNARWGYRMGNAKFVDEMITDGLWDAFNDYHMGITAENIAERWNISREEQDEFAL 180
Query 183 RSLTRAQHAITAGHFQSEIAPVTVATRKGDITVSEDENPG-NAKIDKIPSLRPAFAKDGT 241
S +A+ AI +G F+ EI PV + RKG+ V DE+P + I+ + L+PAF KDGT
Sbjct 181 ASQKKAEEAIKSGQFKDEIVPVVIKGRKGETVVDTDEHPRFGSTIEGLAKLKPAFKKDGT 240
Query 242 ITAANSSSISDGASALLITSEQQAEQRGLKVLAEIKGYTTHSQLPAEFTIAPVGAIEKLL 301
+TA N+S ++D A+ L+I S ++A++ G+K LA+I Y + PA P A + +
Sbjct 241 VTAGNASGLNDCAAVLVIMSAEKAKELGVKPLAKIVSYGSAGVDPAIMGYGPFYATKAAI 300
Query 302 KKIGWTAEEVDLWEINEAFAMVTMAAIDAFKLDAEKVNINGGACALGHPLGSSGSRIIVT 361
+K GWT +E+DL E NEAFA ++A K D KVN+NGGA ALGHP+G+SG+RI+VT
Sbjct 301 EKAGWTVDELDLIESNEAFAAQSLAVAKDLKFDMNKVNVNGGAIALGHPIGASGARILVT 360
Query 362 LIHALKRLGKRKGIAALCIGGGEATALAIE 391
L+HA+++ +KG+A LCIGGG+ TA+ +E
Sbjct 361 LVHAMQKRDAKKGLATLCIGGGQGTAILLE 390
>Q04677 Acetyl-CoA acetyltransferase IB [Candida tropicalis]
Length=403
Score = 347 bits (890), Expect = 8e-121
Identities = 187/398 (47%), Positives = 259/398 (65%), Gaps = 4/398 (1%)
Query 1 LDMSKIMIAAAARTPMGSFQGSLAGLTAPDLGAVVIQRVLEQT-QIPAADIDEVIMGCVL 59
+ + + I + ARTP+GSFQGSL+ LT DLGA ++ L + QI D+DE++ G VL
Sbjct 1 MTLPPVYIVSTARTPIGSFQGSLSSLTYSDLGAHAVKAALAKVPQIKPQDVDEIVFGGVL 60
Query 60 PAGLKQAPARQAMRQAGLPDHVGATTINKVCGSGMKATMFAADAILAGSIQIAVVGGMES 119
A + QAPARQ +AGLPD + A+TINKVC SGMKA + A I+ G+ I VVGG ES
Sbjct 61 QANVGQAPARQVALKAGLPDSIIASTINKVCASGMKAVIIGAQNIICGTSDIVVVGGAES 120
Query 120 MTNSPYLLPKARSGYRMGHGQVLDHMFLDGLEDAYTGRAMGSFAQDMANQKGYTREQMDA 179
M+N+PY LP ARSG R G ++D + DGL D Y + MG A+ A G++RE D
Sbjct 121 MSNTPYYLPSARSGARYGDAVMVDGVQKDGLLDVYEEKLMGVAAEKCAKDHGFSREDQDN 180
Query 180 FAIRSLTRAQHAITAGHFQSEIAPVTVATRKG--DITVSEDENPGNAKIDKIPSLRPAFA 237
FAI S +A A++ G F+SEIAPVT+ +G D + DE G D++ S R F
Sbjct 181 FAINSYKKAGKALSEGKFKSEIAPVTIKGFRGKPDTVIENDEEIGKFNEDRLKSARTVFQ 240
Query 238 KD-GTITAANSSSISDGASALLITSEQQAEQRGLKVLAEIKGYTTHSQLPAEFTIAPVGA 296
K+ GT+TA N+S ++DG +AL++ SE + +Q GLK LA+I G+ ++ P +FTIAP A
Sbjct 241 KENGTVTAPNASKLNDGGAALVLVSEAKLKQLGLKPLAKISGWGEAARTPFDFTIAPALA 300
Query 297 IEKLLKKIGWTAEEVDLWEINEAFAMVTMAAIDAFKLDAEKVNINGGACALGHPLGSSGS 356
+ K +K G T + VD +E+NEAF++V +A + K+ EK+N+ GGA A+GHPLG SG+
Sbjct 301 VPKAVKHAGLTVDRVDFFELNEAFSVVGLANAELVKIPLEKLNVYGGAVAMGHPLGCSGA 360
Query 357 RIIVTLIHALKRLGKRKGIAALCIGGGEATALAIELVD 394
RIIVTL+ L + G R G A +C GGG A+A+ IE +D
Sbjct 361 RIIVTLLSVLTQEGGRFGAAGVCNGGGGASAIVIEKID 398
>P76461 Acetyl-CoA acetyltransferase [Escherichia coli (strain
K12)]
Length=394
Score = 345 bits (886), Expect = 2e-120
Identities = 194/391 (50%), Positives = 253/391 (65%), Gaps = 2/391 (1%)
Query 3 MSKIMIAAAARTPMGSFQGSLAGLTAPDLGAVVIQRVLEQTQIPAADIDEVIMGCVLPAG 62
M +I +A RT +GSF GSLA +A DLGA VI+ +E+ +I + +DEVIMG VL AG
Sbjct 1 MKNCVIVSAVRTAIGSFNGSLASTSAIDLGATVIKAAIERAKIDSQHVDEVIMGNVLQAG 60
Query 63 LKQAPARQAMRQAGLPDHVGATTINKVCGSGMKATMFAADAILAGSIQIAVVGGMESMTN 122
L Q PARQA+ ++GL + V T+NKVCGSG+K+ AA AI AG Q V GGME+M+
Sbjct 61 LGQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAIQAGQAQSIVAGGMENMSL 120
Query 123 SPYLLP-KARSGYRMGHGQVLDHMFLDGLEDAYTGRAMGSFAQDMANQKGYTREQMDAFA 181
+PYLL KARSGYR+G GQV D + DGL A G MG A+++A + G TRE D A
Sbjct 121 APYLLDAKARSGYRLGDGQVYDVILRDGLMCATHGYHMGITAENVAKEYGITREMQDELA 180
Query 182 IRSLTRAQHAITAGHFQSEIAPVTVATRKGDITVSEDENP-GNAKIDKIPSLRPAFAKDG 240
+ S +A AI +G F +EI PV V TRK S+DE P N+ + + +LRPAF K G
Sbjct 181 LHSQRKAAAAIESGAFTAEIVPVNVVTRKKTFVFSQDEFPKANSTAEALGALRPAFDKAG 240
Query 241 TITAANSSSISDGASALLITSEQQAEQRGLKVLAEIKGYTTHSQLPAEFTIAPVGAIEKL 300
T+TA N+S I+DGA+AL+I E A GL LA IK Y + PA + PV A +K
Sbjct 241 TVTAGNASGINDGAAALVIMEESAALAAGLTPLARIKSYASGGVPPALMGMGPVPATQKA 300
Query 301 LKKIGWTAEEVDLWEINEAFAMVTMAAIDAFKLDAEKVNINGGACALGHPLGSSGSRIIV 360
L+ G ++DL E NEAFA +A D+EKVN+NGGA ALGHP+G+SG+RI+V
Sbjct 301 LQLAGLQLADIDLIEANEAFAAQFLAVGKNLGFDSEKVNVNGGAIALGHPIGASGARILV 360
Query 361 TLIHALKRLGKRKGIAALCIGGGEATALAIE 391
TL+HA++ K G+A LCIGGG+ A+ IE
Sbjct 361 TLLHAMQARDKTLGLATLCIGGGQGIAMVIE 391
>Q9UQW6 Acetyl-CoA acetyltransferase [Schizosaccharomyces pombe
(strain 972 / ATCC 24843)]
Length=395
Score = 345 bits (884), Expect = 5e-120
Identities = 188/392 (48%), Positives = 253/392 (65%), Gaps = 2/392 (1%)
Query 4 SKIMIAAAARTPMGSFQGSLAGLTAPDLGAVVIQRVLEQTQIPAADIDEVIMGCVLPAGL 63
+++ I +A RTPMGSF GS A L A LG++ I+ LE+ I +D+DEV MG V+ A L
Sbjct 4 TEVYIVSAVRTPMGSFGGSFASLPATKLGSIAIKGALERVNIKPSDVDEVFMGNVVSANL 63
Query 64 KQAPARQAMRQAGLPDHVGATTINKVCGSGMKATMFAADAILAGSIQIAVVGGMESMTNS 123
Q PARQ AGLP + TT+NKVC SGMKAT+ A I+ G+ +I V GG ESM+N+
Sbjct 64 GQNPARQCALGAGLPRSIVCTTVNKVCASGMKATILGAQTIMTGNAEIVVAGGTESMSNA 123
Query 124 PYLLPKARSGYRMGHGQVLDHMFLDGLEDAYTGRAMGSFAQDMANQKGYTREQMDAFAIR 183
PY PK R G + G+ +++D + DGL DAY G MG+ A+ A + R DAFAI
Sbjct 124 PYYAPKNRFGAKYGNVELVDGLLRDGLSDAYDGLPMGNAAELCAEEHSIDRASQDAFAIS 183
Query 184 SLTRAQHAITAGHFQSEIAPVTVATRKG--DITVSEDENPGNAKIDKIPSLRPAFAKDGT 241
S RAQ+A F+ EI PV V +G + V+EDE P N DK+ S+R F +GT
Sbjct 184 SYKRAQNAQATKAFEQEIVPVEVPVGRGKPNKLVTEDEEPKNLNEDKLKSVRAVFKSNGT 243
Query 242 ITAANSSSISDGASALLITSEQQAEQRGLKVLAEIKGYTTHSQLPAEFTIAPVGAIEKLL 301
+TAAN+S+++DGASAL++ S + ++ GLK LA+I G+ +Q P FT +P AI K L
Sbjct 244 VTAANASTLNDGASALVLMSAAKVKELGLKPLAKIIGWGEAAQDPERFTTSPSLAIPKAL 303
Query 302 KKIGWTAEEVDLWEINEAFAMVTMAAIDAFKLDAEKVNINGGACALGHPLGSSGSRIIVT 361
K G A +VD +EINEAF++V +A LD E+VNINGG A+GHPLGSSGSRII T
Sbjct 304 KHAGIEASQVDYYEINEAFSVVAVANTKILGLDPERVNINGGGVAMGHPLGSSGSRIICT 363
Query 362 LIHALKRLGKRKGIAALCIGGGEATALAIELV 393
L + L + + G+AA+C GGG A+++ IE V
Sbjct 364 LAYILAQKDAKIGVAAVCNGGGGASSIVIERV 395
>Q12598 Acetyl-CoA acetyltransferase IA [Candida tropicalis]
Length=403
Score = 344 bits (883), Expect = 9e-120
Identities = 185/393 (47%), Positives = 257/393 (65%), Gaps = 4/393 (1%)
Query 6 IMIAAAARTPMGSFQGSLAGLTAPDLGAVVIQRVLEQT-QIPAADIDEVIMGCVLPAGLK 64
+ I + ARTP+GSFQGSL+ LT DLGA ++ L + QI D+DE++ G VL A +
Sbjct 6 VYIVSTARTPIGSFQGSLSSLTYSDLGAHAVKAALAKVPQIKPQDVDEIVFGGVLQANVG 65
Query 65 QAPARQAMRQAGLPDHVGATTINKVCGSGMKATMFAADAILAGSIQIAVVGGMESMTNSP 124
QAPARQ +AGLPD + A+TINKVC SGMKA + A I+ G+ I VVGG ESM+N+P
Sbjct 66 QAPARQVALKAGLPDSIVASTINKVCASGMKAVIIGAQNIICGTSDIVVVGGAESMSNTP 125
Query 125 YLLPKARSGYRMGHGQVLDHMFLDGLEDAYTGRAMGSFAQDMANQKGYTREQMDAFAIRS 184
Y LP ARSG R G ++D + DGL D Y + MG A+ A G++RE D FAI S
Sbjct 126 YYLPSARSGARYGDAIMVDGVQKDGLLDVYEEKLMGVAAEKCAKDHGFSREDQDNFAINS 185
Query 185 LTRAQHAITAGHFQSEIAPVTVATRKG--DITVSEDENPGNAKIDKIPSLRPAFAKD-GT 241
+A A++ G F+SEIAPVT+ +G D + DE G +++ S R F K+ GT
Sbjct 186 YKKAGKALSEGKFKSEIAPVTIKGFRGKPDTVIENDEEIGKFNEERLKSARTVFQKENGT 245
Query 242 ITAANSSSISDGASALLITSEQQAEQRGLKVLAEIKGYTTHSQLPAEFTIAPVGAIEKLL 301
+TA N+S ++DG +AL++ SE + +Q GLK LA+I G+ ++ P +FTIAP A+ K +
Sbjct 246 VTAPNASKLNDGGAALVLVSEAKLKQLGLKPLAKISGWGEAARTPFDFTIAPALAVPKAV 305
Query 302 KKIGWTAEEVDLWEINEAFAMVTMAAIDAFKLDAEKVNINGGACALGHPLGSSGSRIIVT 361
K G T + VD +E+NEAF++V +A + + EK+N+ GGA A+GHPLG SG+RIIVT
Sbjct 306 KHAGLTVDRVDFFELNEAFSVVGLANAELVNIPLEKLNVYGGAVAMGHPLGCSGARIIVT 365
Query 362 LIHALKRLGKRKGIAALCIGGGEATALAIELVD 394
L+ L + G R G+A +C GGG A+A+ IE +D
Sbjct 366 LLSVLTQEGGRFGVAGVCNGGGGASAVVIEKID 398
>P44873 Acetyl-CoA acetyltransferase [Haemophilus influenzae (strain
ATCC 51907 / DSM 11121 / KW20 / Rd)]
Length=393
Score = 343 bits (881), Expect = 1e-119
Identities = 183/391 (47%), Positives = 255/391 (65%), Gaps = 2/391 (1%)
Query 3 MSKIMIAAAARTPMGSFQGSLAGLTAPDLGAVVIQRVLEQTQIPAADIDEVIMGCVLPAG 62
M ++I +A RTP+GSF G+L+ ++A DLGA+VIQ +++ I +A ++EVIMG VL AG
Sbjct 1 MENVVIVSAVRTPIGSFNGALSSVSAVDLGAIVIQEAIKRANIESALVNEVIMGNVLQAG 60
Query 63 LKQAPARQAMRQAGLPDHVGATTINKVCGSGMKATMFAADAILAGSIQIAVVGGMESMTN 122
L Q PARQA +AG+ + + TINKVCGSG+K+ A +I++G I VVGGME+M+
Sbjct 61 LGQNPARQAALKAGIEKEIPSLTINKVCGSGLKSVALGAQSIISGDADIVVVGGMENMSQ 120
Query 123 SPYLLP-KARSGYRMGHGQVLDHMFLDGLEDAYTGRAMGSFAQDMANQKGYTREQMDAFA 181
+PYLL K R G +MG+ + D M DGL A MG A+++A Q G +R+ D A
Sbjct 121 APYLLDSKVRQGVKMGNLTLRDTMIEDGLTCASNHYHMGITAENIAEQYGISRQAQDELA 180
Query 182 IRSLTRAQHAITAGHFQSEIAPVTVATRKGDITVSEDENP-GNAKIDKIPSLRPAFAKDG 240
+RS T A A+ G F EI PV V TRKGDI VS DE P + + + L+PAF K+G
Sbjct 181 LRSQTLASQAVQLGVFDKEIVPVMVKTRKGDIIVSRDEYPKADTTAEGLAKLKPAFKKEG 240
Query 241 TITAANSSSISDGASALLITSEQQAEQRGLKVLAEIKGYTTHSQLPAEFTIAPVGAIEKL 300
T+TA N+S I+DGA+AL++ SE +A GLK +A+I+ Y + P+ + PV A +K
Sbjct 241 TVTAGNASGINDGAAALILVSESKAHALGLKAIAKIRSYASGGVDPSVMGLGPVPATQKA 300
Query 301 LKKIGWTAEEVDLWEINEAFAMVTMAAIDAFKLDAEKVNINGGACALGHPLGSSGSRIIV 360
LKK G +++DL E NEAFA + LD K NI+GGA ALGHP+G+SG+RI+V
Sbjct 301 LKKAGINLDDIDLIEANEAFASQFLGVGKDLNLDMNKTNIHGGAIALGHPIGASGARILV 360
Query 361 TLIHALKRLGKRKGIAALCIGGGEATALAIE 391
TL+H L K+ G+A LCIGGG+ ++ +E
Sbjct 361 TLLHNLIEKDKKLGLATLCIGGGQGISMIVE 391
>Q86AD9 Probable acetyl-CoA acetyltransferase [Dictyostelium discoideum]
Length=414
Score = 338 bits (867), Expect = 3e-117
Identities = 182/391 (47%), Positives = 241/391 (62%), Gaps = 1/391 (0%)
Query 2 DMSKIMIAAAARTPMGSFQGSLAGLTAPDLGAVVIQRVLEQTQIPAADIDEVIMGCVLPA 61
++ ++I +A RTP+GS GSL+ + L ++ I+ +++ I +D+DE I+G V+ A
Sbjct 22 NLESVVIVSAVRTPIGSIGGSLSTIPGTKLSSITIEEAVKRAGIKPSDVDEAIIGNVISA 81
Query 62 GLKQAPARQAMRQAGLPDHVGATTINKVCGSGMKATMFAADAILAGSIQIAVVGGMESMT 121
L QAPARQ AGL TTINKVC SGMKA +F A +I G + V GG ESM+
Sbjct 82 NLGQAPARQCALGAGLEQKTITTTINKVCSSGMKAIVFGAQSIALGHSKTVVAGGFESMS 141
Query 122 NSPYLLPKARSGYRMGHGQVLDHMFLDGLEDAYTGRAMGSFAQDMANQKGYTREQMDAFA 181
PY K R G + G+ +D + DGL DAY G AMG D A++ TREQ D FA
Sbjct 142 QVPYYADKMRFGAKYGNQTFIDGLVRDGLADAYNGSAMGVCGDDCADKYKITREQQDKFA 201
Query 182 IRSLTRAQHAITAGHFQSEIAPVTVATRKGDIT-VSEDENPGNAKIDKIPSLRPAFAKDG 240
+ S RA A G F EI V + R G +T V EDE P DKIP+L+PAF +G
Sbjct 202 VDSYLRALEAQKNGFFNDEIVQVPIVGRGGKVTYVVEDEEPKKVLFDKIPNLKPAFTPNG 261
Query 241 TITAANSSSISDGASALLITSEQQAEQRGLKVLAEIKGYTTHSQLPAEFTIAPVGAIEKL 300
T+T AN+S ++DGAS++++ SE A++ GLK LA I GY Q P EF AP AI K
Sbjct 262 TVTPANASKLNDGASSVILMSESHAKELGLKPLARIIGYADAEQAPIEFPTAPALAIPKA 321
Query 301 LKKIGWTAEEVDLWEINEAFAMVTMAAIDAFKLDAEKVNINGGACALGHPLGSSGSRIIV 360
LK G +VDL+EINEAFA+V +A +D K+N+NGGA ALGHP+GSSG RI+V
Sbjct 322 LKNAGINMSQVDLFEINEAFAVVGLANAKILDIDHNKLNVNGGAVALGHPIGSSGCRIVV 381
Query 361 TLIHALKRLGKRKGIAALCIGGGEATALAIE 391
TL H L+ + G+AA+C GGG +TAL +E
Sbjct 382 TLTHLLQNKNLKYGVAAICNGGGGSTALVLE 412
>Q6L8K7 Acetyl-CoA acetyltransferase [Yarrowia lipolytica (strain
CLIB 122 / E 150)]
Length=397
Score = 337 bits (864), Expect = 5e-117
Identities = 180/386 (47%), Positives = 247/386 (64%), Gaps = 5/386 (1%)
Query 8 IAAAARTPMGSFQGSLAGLTAPDLGAVVIQRVLEQTQIPAADIDEVIMGCVLPAGLKQAP 67
I AARTP+G F G+L ++A DLG + ++++++PA IDE + G VL A QAP
Sbjct 13 IVGAARTPVGKFNGALKSVSAIDLGITAAKAAVQRSKVPADQIDEFLFGQVLTANSGQAP 72
Query 68 ARQAMRQAGLPDHVGATTINKVCGSGMKATMFAADAILAGSIQIAVVGGMESMTNSPYLL 127
ARQ + + G P+ V ATTINKVC SG+K AA AI AG + V GGMESM+N+PY
Sbjct 73 ARQVVIKGGFPESVEATTINKVCSSGLKTVALAAQAIKAGDRNVIVAGGMESMSNTPYYS 132
Query 128 PKARSGYRMGHGQVLDHMFLDGLEDAYTGRAMGSFAQDMANQKGYTREQMDAFAIRSLTR 187
+ G G+ ++ D + DGL D Y MG+ ++ + G TREQ D +AI S R
Sbjct 133 GR---GLVFGNQKLEDSIVKDGLWDPYNNIHMGNCCENTNKRDGITREQQDEYAIESYRR 189
Query 188 AQHAITAGHFQSEIAPVTVATRKGDITVSEDENPGNAKIDKIPSLRPAFAKDGTITAANS 247
A +I G F+ EI PV + TRKG +TVSEDE P A +K+ L+P F K G++TA N+
Sbjct 190 ANESIKNGAFKDEIVPVEIKTRKGTVTVSEDEEPKGANAEKLKGLKPVFDKQGSVTAGNA 249
Query 248 SSISDGASALLITSEQQAEQRGLKVLAEIKGYTTHSQLPAEFTIAPVGAIEKLLKKIGWT 307
S I+DGASA+++ S +A++ G VLA+I Y + P +FTIAP AI LKK G T
Sbjct 250 SPINDGASAVVVASGTKAKELGTPVLAKIVSYADAATAPIDFTIAPSLAIPAALKKAGLT 309
Query 308 AEEVDLWEINEAFAMVTMAAIDAFKLDAEKVNINGGACALGHPLGSSGSRIIVTLIHALK 367
+++ LWEINEAF+ V +A + +D KVN+ GGA ALGHP+G+SG+RI VTL++ALK
Sbjct 310 KDDIALWEINEAFSGVALANLMRLGIDKSKVNVKGGAVALGHPIGASGNRIFVTLVNALK 369
Query 368 RLGKRKGIAALCIGGGEATALAIELV 393
G+AA+C GGG +TA+ I+ V
Sbjct 370 E--GEYGVAAICNGGGASTAIVIKKV 393
>Q0AVM3 Acetyl-CoA acetyltransferase [Syntrophomonas wolfei subsp.
wolfei (strain DSM 2245B / Goettingen)]
Length=396
Score = 337 bits (863), Expect = 8e-117
Identities = 176/391 (45%), Positives = 254/391 (65%), Gaps = 4/391 (1%)
Query 5 KIMIAAAARTPMGSFQGSLAGLTAPDLGAVVIQRVLEQTQIPAADIDEVIMGCVLPAGLK 64
++++ A RTP+G+F G+L + + LGA+V+ +++ I A IDEVI GCVL AGL
Sbjct 4 EVVLVGACRTPVGTFGGTLKDVGSAQLGAIVMGEAIKRAGIKAEQIDEVIFGCVLQAGLG 63
Query 65 QAPARQAMRQAGLPDHVGATTINKVCGSGMKATMFAADAILAGSIQIAVVGGMESMTNSP 124
Q ARQ M AG+P V A TINKVCGSG++A AA I AG I + GG E+M +P
Sbjct 64 QNVARQCMINAGIPKEVTAFTINKVCGSGLRAVSLAAQVIKAGDADIIMAGGTENMDKAP 123
Query 125 YLLPKARSGYRMG--HGQVLDHMFLDGLEDAYTGRAMGSFAQDMANQKGYTREQMDAFAI 182
++LP AR GYRM G ++D M GL D + G MG A+++ + G TRE+ DAF
Sbjct 124 FILPNARWGYRMSMPKGDLIDEMVWGGLTDVFNGYHMGITAENINDMYGITREEQDAFGF 183
Query 183 RSLTRAQHAITAGHFQSEIAPVTVATRKGDITVSEDENPGNAKIDKIPSLRPAFAKDGTI 242
RS T A AI +G F+ EI PV + +KGDI DE+P + + + L PAF K G++
Sbjct 184 RSQTLAAQAIESGRFKDEIVPVVIKGKKGDIVFDTDEHPRKSTPEAMAKLAPAFKKGGSV 243
Query 243 TAANSSSISDGASALLITSEQQAEQRGLKVLAEIKGYTTHSQLPAEFTIAPVGAIEKLLK 302
TA N+S I+D A+A+++ S+++A++ G+K +A++ Y + P+ + P+ A K L+
Sbjct 244 TAGNASGINDAAAAVIVMSKEKADELGIKPMAKVVSYASGGVDPSVMGLGPIPASRKALE 303
Query 303 KIGWTAEEVDLWEINEAFAMVTMA-AIDAFKLD-AEKVNINGGACALGHPLGSSGSRIIV 360
K G T +++DL E NEAFA ++A A D D EKVN+NGGA A+GHP+GSSG+RI+V
Sbjct 304 KAGLTIDDIDLIEANEAFAAQSIAVARDLGWADKMEKVNVNGGAIAIGHPIGSSGARILV 363
Query 361 TLIHALKRLGKRKGIAALCIGGGEATALAIE 391
TL++ +++ G +KG+A LCIGGG TAL +E
Sbjct 364 TLLYEMQKRGSKKGLATLCIGGGMGTALIVE 394
>A0A1D8PH52 Acetyl-CoA acetyltransferase [Candida albicans (strain
SC5314 / ATCC MYA-2876)]
Length=402
Score = 336 bits (861), Expect = 2e-116
Identities = 182/393 (46%), Positives = 256/393 (65%), Gaps = 4/393 (1%)
Query 6 IMIAAAARTPMGSFQGSLAGLTAPDLGAVVIQRVLEQT-QIPAADIDEVIMGCVLPAGLK 64
+ I + ARTP+GSFQG+L+ LT DLGA ++ L + QI D+DE++ G VL A +
Sbjct 5 VYIVSTARTPIGSFQGTLSSLTYSDLGAHAVKAALNKVPQIKPEDVDEIVFGGVLQANVG 64
Query 65 QAPARQAMRQAGLPDHVGATTINKVCGSGMKATMFAADAILAGSIQIAVVGGMESMTNSP 124
QAPARQ +AGL D + A+T+NKVC SG+KA + A I+ G+ I VVGG ESMTN+P
Sbjct 65 QAPARQVALKAGLTDKIVASTVNKVCASGLKAIIIGAQNIICGTSDIVVVGGAESMTNTP 124
Query 125 YLLPKARSGYRMGHGQVLDHMFLDGLEDAYTGRAMGSFAQDMANQKGYTREQMDAFAIRS 184
Y LP AR+G R G ++D + DGL D Y + MG A+ A G+TREQ D FAI+S
Sbjct 125 YYLPTARNGARFGDSTLIDGIQKDGLLDVYEQKLMGVAAEKCAADHGFTREQQDEFAIKS 184
Query 185 LTRAQHAITAGHFQSEIAPVTVATRKG--DITVSEDENPGNAKIDKIPSLRPAFAKD-GT 241
+A +A+ G F EIAPVT+ +G D+ V +DE K+ S R F K+ GT
Sbjct 185 YQKAGNALKQGKFNQEIAPVTIKGVRGKPDVVVEKDEEIEKFNEAKLKSARAVFQKENGT 244
Query 242 ITAANSSSISDGASALLITSEQQAEQRGLKVLAEIKGYTTHSQLPAEFTIAPVGAIEKLL 301
+T N+S I+DGA+AL++ SE + ++ GLK LA+I G+ ++ P +FTIAP A+ K +
Sbjct 245 VTGPNASKINDGAAALILVSEAKLKELGLKPLAKINGWGEAARNPIDFTIAPALAVPKAV 304
Query 302 KKIGWTAEEVDLWEINEAFAMVTMAAIDAFKLDAEKVNINGGACALGHPLGSSGSRIIVT 361
K G T ++VD +E+NEAF++V +A + ++ EK+N GGA ALGHPLG SG+RI+VT
Sbjct 305 KHAGLTLDQVDFFELNEAFSVVGLANAEICQIPLEKLNAYGGAVALGHPLGCSGARIVVT 364
Query 362 LIHALKRLGKRKGIAALCIGGGEATALAIELVD 394
L+ L + G + G A +C GGG A+++ IE VD
Sbjct 365 LLSVLIQEGGKIGCAGVCNGGGGASSIVIEKVD 397
>P45369 Acetyl-CoA acetyltransferase [Allochromatium vinosum (strain
ATCC 17899 / DSM 180 / NBRC 103801 / NCIMB 10441 / D)]
Length=394
Score = 335 bits (858), Expect = 4e-116
Identities = 174/388 (45%), Positives = 252/388 (65%), Gaps = 2/388 (1%)
Query 6 IMIAAAARTPMGSFQGSLAGLTAPDLGAVVIQRVLEQTQIPAADIDEVIMGCVLPAGLKQ 65
I+I A R+ +G+F GSL+ L+A ++G V++ +L +T + IDEVI+G VL AG+ Q
Sbjct 5 IVIVDAGRSAIGTFSGSLSSLSATEIGTAVLKGLLARTGLAPEQIDEVILGQVLTAGVGQ 64
Query 66 APARQAMRQAGLPDHVGATTINKVCGSGMKATMFAADAILAGSIQIAVVGGMESMTNSPY 125
PARQ +AGLP V A TINKVCGSG+KA A AI G I + GG ESM+ S +
Sbjct 65 NPARQTTLKAGLPHSVPAMTINKVCGSGLKAVHLAMQAIACGDADIVIAGGQESMSQSSH 124
Query 126 LLPKARSGYRMGHGQVLDHMFLDGLEDAYTGRAMGSFAQDMANQKGYTREQMDAFAIRSL 185
+LP++R G RMG + D M +DGL DA+ MG+ A+++A + G+TREQ DAFA S
Sbjct 125 VLPRSRDGQRMGDWSMKDTMIVDGLWDAFNNYHMGTTAENIAQKYGFTREQQDAFAAASQ 184
Query 186 TRAQHAITAGHFQSEIAPVTVATRKGDITVSE-DENPGN-AKIDKIPSLRPAFAKDGTIT 243
+ + A AG FQ EI P+ + RKGD V + DE P + + + LRPAF++DG++T
Sbjct 185 QKTEAAQKAGRFQDEIIPIEIPQRKGDPKVFDADEFPRHGTTAESLGKLRPAFSRDGSVT 244
Query 244 AANSSSISDGASALLITSEQQAEQRGLKVLAEIKGYTTHSQLPAEFTIAPVGAIEKLLKK 303
A N+S I+DGA+ +++ E +A++ GLK +A + + + PA P+ A K L+K
Sbjct 245 AGNASGINDGAAMVVVMKESKAKELGLKPMARLVAFASAGVDPAIMGTGPIPASTKCLEK 304
Query 304 IGWTAEEVDLWEINEAFAMVTMAAIDAFKLDAEKVNINGGACALGHPLGSSGSRIIVTLI 363
GWT ++DL E NEAFA M+ D KVN+NGGA A+GHP+G+SG+R++VTL+
Sbjct 305 AGWTPADLDLIEANEAFAAQAMSVNQDMGWDLSKVNVNGGAIAIGHPIGASGARVLVTLL 364
Query 364 HALKRLGKRKGIAALCIGGGEATALAIE 391
+ +++ +KG+A LCIGGG+ ALA+E
Sbjct 365 YEMQKRDAKKGLATLCIGGGQGVALAVE 392
Lambda K H a alpha
0.319 0.133 0.376 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1686750
Database: d083b41a74de0ec8bdd58c2017f0e73b.SwissProt.fasta
Posted date: May 18, 2024 8:30 PM
Number of letters in database: 5,561
Number of sequences in database: 14
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
