ACIAD2530 / SwissProt Alignments

BLASTP 2.12.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: d0da4841fadff97a65b9ebf61e362e7e.SwissProt.fasta
           14 sequences; 2,696 total letters



Query= ACIAD2530

Length=199
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

P0A9U7 HTH-type transcriptional regulator PuuR [Shigella flexneri]    68.9    2e-18
P0A9U6 HTH-type transcriptional regulator PuuR [Escherichia coli ...  68.9    2e-18
P22753 HTH-type transcriptional regulator SinR [Bacillus lichenif...  52.8    5e-13
P06533 HTH-type transcriptional regulator SinR [Bacillus subtilis...  49.7    7e-12
A0QVU1 Transcriptional regulator ClgR [Mycolicibacterium smegmati...  49.7    8e-12
P77626 HTH-type transcriptional regulator SutR [Escherichia coli ...  48.5    6e-11
C1D3U5 HTH-type transcriptional regulator DdrOP3 [Deinococcus des...  41.6    9e-09
C1CYP4 HTH-type transcriptional regulator DdrOC [Deinococcus dese...  40.4    2e-08
P44030 Uncharacterized HTH-type transcriptional regulator HI_0659...  37.4    2e-07
P9WMI0 HTH-type transcriptional regulator RamB [Mycobacterium tub...  37.4    8e-07
P9WMI1 HTH-type transcriptional regulator RamB [Mycobacterium tub...  37.4    8e-07
Q8TK90 Putative HTH-type transcriptional regulatory protein MA_35...  37.0    1e-06
Q8FHF3 Antitoxin HipB [Escherichia coli O6:H1 (strain CFT073 / AT...  33.9    3e-06
P23873 Antitoxin HipB [Escherichia coli (strain K12)]                 33.1    5e-06


>P0A9U7 HTH-type transcriptional regulator PuuR [Shigella flexneri]
Length=185

 Score = 68.9 bits (167),  Expect = 2e-18
 Identities = 38/161 (24%), Positives = 76/161 (47%), Gaps = 5/161 (3%)

Query  15   GIQIKRHRQEQGLKLSEVAQIAGISQGMLSKIENAQVSTSLETLSRLCDVLGIPMSTLFS  74
            G ++   RQ+QGL     A+++G++   +S IE  +VS ++ TL +L  V G+ +S  FS
Sbjct  9    GKRLSEIRQQQGLSQRRAAELSGLTHSAISTIEQDKVSPAISTLQKLLKVYGLSLSEFFS  68

Query  75   QYDQQESHAMLVKSGDGMEVVRRGTEKGHTYRLLTHSRGPRKNFEAYLVSMDDASEEFPT  134
            + ++ +   +++   D +E+  +G         L H+  P +       +    +     
Sbjct  69   EPEKPDEPQVVINQDDLIEMGSQGVS-----MKLVHNGNPNRTLAMIFETYQPGTTTGER  123

Query  135  FAHPGTEMLYLVEGELIYRHGQEVFHMQPGDCLTLEGEIPH  175
              H G E+  ++EGE++     + +H+  G    +   IPH
Sbjct  124  IKHQGEEIGTVLEGEIVLTINGQDYHLVAGQSYAINTGIPH  164


>P0A9U6 HTH-type transcriptional regulator PuuR [Escherichia coli 
(strain K12)]
Length=185

 Score = 68.9 bits (167),  Expect = 2e-18
 Identities = 38/161 (24%), Positives = 76/161 (47%), Gaps = 5/161 (3%)

Query  15   GIQIKRHRQEQGLKLSEVAQIAGISQGMLSKIENAQVSTSLETLSRLCDVLGIPMSTLFS  74
            G ++   RQ+QGL     A+++G++   +S IE  +VS ++ TL +L  V G+ +S  FS
Sbjct  9    GKRLSEIRQQQGLSQRRAAELSGLTHSAISTIEQDKVSPAISTLQKLLKVYGLSLSEFFS  68

Query  75   QYDQQESHAMLVKSGDGMEVVRRGTEKGHTYRLLTHSRGPRKNFEAYLVSMDDASEEFPT  134
            + ++ +   +++   D +E+  +G         L H+  P +       +    +     
Sbjct  69   EPEKPDEPQVVINQDDLIEMGSQGVS-----MKLVHNGNPNRTLAMIFETYQPGTTTGER  123

Query  135  FAHPGTEMLYLVEGELIYRHGQEVFHMQPGDCLTLEGEIPH  175
              H G E+  ++EGE++     + +H+  G    +   IPH
Sbjct  124  IKHQGEEIGTVLEGEIVLTINGQDYHLVAGQSYAINTGIPH  164


>P22753 HTH-type transcriptional regulator SinR [Bacillus licheniformis]
Length=111

 Score = 52.8 bits (125),  Expect = 5e-13
 Identities = 28/73 (38%), Positives = 48/73 (66%), Gaps = 1/73 (1%)

Query  14  IGIQIKRHRQEQGLKLSEVAQIAGISQGMLSKIE-NAQVSTSLETLSRLCDVLGIPMSTL  72
           IG +IK++R+E+G  LSE+A+ AG+++  LS IE N Q + S++ L ++  VL + + TL
Sbjct  2   IGQRIKQYRKEKGYSLSELAEKAGVAKSYLSSIERNLQTNPSIQFLEKVSAVLDVSVHTL  61

Query  73  FSQYDQQESHAML  85
            ++ D+ E    L
Sbjct  62  LNEKDETEYDGQL  74


>P06533 HTH-type transcriptional regulator SinR [Bacillus subtilis 
(strain 168)]
Length=111

 Score = 49.7 bits (117),  Expect = 7e-12
 Identities = 27/73 (37%), Positives = 46/73 (63%), Gaps = 1/73 (1%)

Query  14  IGIQIKRHRQEQGLKLSEVAQIAGISQGMLSKIE-NAQVSTSLETLSRLCDVLGIPMSTL  72
           IG +IK++R+E+G  LSE+A+ AG+++  LS IE N Q + S++ L ++  VL + + TL
Sbjct  2   IGQRIKQYRKEKGYSLSELAEKAGVAKSYLSSIERNLQTNPSIQFLEKVSAVLDVSVHTL  61

Query  73  FSQYDQQESHAML  85
             +  + E    L
Sbjct  62  LDEKHETEYDGQL  74


>A0QVU1 Transcriptional regulator ClgR [Mycolicibacterium smegmatis 
(strain ATCC 700084 / mc(2)155)]
Length=112

 Score = 49.7 bits (117),  Expect = 8e-12
 Identities = 28/74 (38%), Positives = 42/74 (57%), Gaps = 2/74 (3%)

Query  10  LEQYIGIQIKRHRQEQGLKLSEVAQIAGISQGMLSKIENAQVSTSLETLSRLCDVLGIPM  69
           L + IG  ++  R +QG  L EV+  A +S G LS++E  +   S E LS +CD L +P+
Sbjct  5   LREVIGDVLRNARTDQGRTLREVSDAARVSLGYLSEVERGRKEASSELLSAICDALDVPL  64

Query  70  STLFSQYDQQESHA  83
           S + +  D  ES A
Sbjct  65  SRVLT--DAGESMA  76


>P77626 HTH-type transcriptional regulator SutR [Escherichia coli 
(strain K12)]
Length=178

 Score = 48.5 bits (114),  Expect = 6e-11
 Identities = 28/87 (32%), Positives = 49/87 (56%), Gaps = 9/87 (10%)

Query  10  LEQYIGIQIKRHRQEQGLKLSEVAQIAGISQGMLSKIENAQVSTSLETLSRLCDVLGIPM  69
           L +++   +K+ RQ++G  LS +A+  G+S+ ML +IE  + S ++ TL ++   L +P 
Sbjct  4   LARFLSTTLKQLRQQRGWSLSRLAEATGVSKAMLGQIERNESSPTVATLWKIATGLNVPF  63

Query  70  STLFSQ--------YDQQESHAMLVKS  88
           ST  S         YD Q+  AM++ S
Sbjct  64  STFISPPQSATPSVYDPQQ-QAMVITS  89


>C1D3U5 HTH-type transcriptional regulator DdrOP3 [Deinococcus 
deserti (strain DSM 17065 / CIP 109153 / LMG 22923 / VCD115)]
Length=129

 Score = 41.6 bits (96),  Expect = 9e-09
 Identities = 22/56 (39%), Positives = 33/56 (59%), Gaps = 0/56 (0%)

Query  17  QIKRHRQEQGLKLSEVAQIAGISQGMLSKIENAQVSTSLETLSRLCDVLGIPMSTL  72
           +++  RQE+GL+L ++A  A IS   LS +E  + + SLETL  L    GI +  L
Sbjct  6   RLRELRQERGLRLKDIAGAAQISVPYLSDLERGRTNPSLETLQSLASTYGITVHDL  61


>C1CYP4 HTH-type transcriptional regulator DdrOC [Deinococcus 
deserti (strain DSM 17065 / CIP 109153 / LMG 22923 / VCD115)]
Length=129

 Score = 40.4 bits (93),  Expect = 2e-08
 Identities = 21/56 (38%), Positives = 33/56 (59%), Gaps = 0/56 (0%)

Query  17  QIKRHRQEQGLKLSEVAQIAGISQGMLSKIENAQVSTSLETLSRLCDVLGIPMSTL  72
           +++  R E+GL+L +VA++A IS   LS +E  + + SLETL  L     I +  L
Sbjct  6   RLRELRSERGLRLKDVAEVAQISVPYLSDLERGRTNPSLETLQTLAGAYNITVHDL  61


>P44030 Uncharacterized HTH-type transcriptional regulator HI_0659 
[Haemophilus influenzae (strain ATCC 51907 / DSM 11121 
/ KW20 / Rd)]
Length=98

 Score = 37.4 bits (85),  Expect = 2e-07
 Identities = 17/49 (35%), Positives = 30/49 (61%), Gaps = 0/49 (0%)

Query  22  RQEQGLKLSEVAQIAGISQGMLSKIENAQVSTSLETLSRLCDVLGIPMS  70
           RQ+ G+   ++  ++G+ Q M+++IE  Q +  LETL +L   LG  +S
Sbjct  41  RQQLGISQKQLETLSGVKQPMIARIEKGQTNPQLETLLKLLAPLGKTLS  89


>P9WMI0 HTH-type transcriptional regulator RamB [Mycobacterium 
tuberculosis (strain CDC 1551 / Oshkosh)]
Length=474

 Score = 37.4 bits (85),  Expect = 8e-07
 Identities = 19/65 (29%), Positives = 37/65 (57%), Gaps = 0/65 (0%)

Query  13  YIGIQIKRHRQEQGLKLSEVAQIAGISQGMLSKIENAQVSTSLETLSRLCDVLGIPMSTL  72
           Y+G ++++ R E+G   + +AQ+  IS   L++IE+     ++  L R+ +V G+  +  
Sbjct  5   YVGSRVRQLRNERGFSQAALAQMLEISPSYLNQIEHDVRPLTVAVLLRITEVFGVDATFF  64

Query  73  FSQYD  77
            SQ D
Sbjct  65  ASQDD  69


 Score = 17.3 bits (33),  Expect = 2.5
 Identities = 5/16 (31%), Positives = 11/16 (69%), Gaps = 0/16 (0%)

Query  132  FPTFAHPGTEMLYLVE  147
            + TFA+PG  ++ + +
Sbjct  357  YETFANPGKILVQIAQ  372


>P9WMI1 HTH-type transcriptional regulator RamB [Mycobacterium 
tuberculosis (strain ATCC 25618 / H37Rv)]
Length=474

 Score = 37.4 bits (85),  Expect = 8e-07
 Identities = 19/65 (29%), Positives = 37/65 (57%), Gaps = 0/65 (0%)

Query  13  YIGIQIKRHRQEQGLKLSEVAQIAGISQGMLSKIENAQVSTSLETLSRLCDVLGIPMSTL  72
           Y+G ++++ R E+G   + +AQ+  IS   L++IE+     ++  L R+ +V G+  +  
Sbjct  5   YVGSRVRQLRNERGFSQAALAQMLEISPSYLNQIEHDVRPLTVAVLLRITEVFGVDATFF  64

Query  73  FSQYD  77
            SQ D
Sbjct  65  ASQDD  69


 Score = 17.3 bits (33),  Expect = 2.5
 Identities = 5/16 (31%), Positives = 11/16 (69%), Gaps = 0/16 (0%)

Query  132  FPTFAHPGTEMLYLVE  147
            + TFA+PG  ++ + +
Sbjct  357  YETFANPGKILVQIAQ  372


>Q8TK90 Putative HTH-type transcriptional regulatory protein MA_3524 
[Methanosarcina acetivorans (strain ATCC 35395 / DSM 
2834 / JCM 12185 / C2A)]
Length=328

 Score = 37.0 bits (84),  Expect = 1e-06
 Identities = 17/61 (28%), Positives = 36/61 (59%), Gaps = 3/61 (5%)

Query  13   YIGIQ---IKRHRQEQGLKLSEVAQIAGISQGMLSKIENAQVSTSLETLSRLCDVLGIPM  69
            YI I+   +K+ R +Q + L  +A + G+S+  +SK E   +  S++ + +L D+ G+ +
Sbjct  124  YISIEGDLLKKARTDQSMSLGTLASMVGVSRRTISKYEEEGMDASIDVVLQLEDIFGVEL  183

Query  70   S  70
            +
Sbjct  184  A  184


 Score = 15.4 bits (28),  Expect = 10.0
 Identities = 4/14 (29%), Positives = 9/14 (64%), Gaps = 0/14 (0%)

Query  63   DVLGIPMSTLFSQY  76
            D+L + + TL+  +
Sbjct  95   DILALNVQTLYDYF  108


>Q8FHF3 Antitoxin HipB [Escherichia coli O6:H1 (strain CFT073 
/ ATCC 700928 / UPEC)]
Length=94

 Score = 33.9 bits (76),  Expect = 3e-06
 Identities = 19/53 (36%), Positives = 29/53 (55%), Gaps = 0/53 (0%)

Query  18  IKRHRQEQGLKLSEVAQIAGISQGMLSKIENAQVSTSLETLSRLCDVLGIPMS  70
           +K  RQ+ G   SE+A+  GI Q  +S  EN   +TSL T  ++   L + M+
Sbjct  23  MKLVRQQNGWTQSELAKKIGIKQATISNFENNPDNTSLTTFFKILQSLELSMT  75


>P23873 Antitoxin HipB [Escherichia coli (strain K12)]
Length=88

 Score = 33.1 bits (74),  Expect = 5e-06
 Identities = 20/64 (31%), Positives = 33/64 (52%), Gaps = 0/64 (0%)

Query  18  IKRHRQEQGLKLSEVAQIAGISQGMLSKIENAQVSTSLETLSRLCDVLGIPMSTLFSQYD  77
           +K  RQ+ G   SE+A+  GI Q  +S  EN   +T+L T  ++   L + M+   ++  
Sbjct  17  MKLVRQQNGWTQSELAKKIGIKQATISNFENNPDNTTLTTFFKILQSLELSMTLCDAKNA  76

Query  78  QQES  81
             ES
Sbjct  77  SPES  80



Lambda      K        H        a         alpha
   0.319    0.135    0.385    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 348404


  Database: d0da4841fadff97a65b9ebf61e362e7e.SwissProt.fasta
    Posted date:  May 20, 2024  9:21 AM
  Number of letters in database: 2,696
  Number of sequences in database:  14



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40