BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 4c45e3182855df64718d7a592c597c61.SwissProt.fasta
17 sequences; 6,992 total letters
Query= ACIAD2554
Length=289
Score E
Sequences producing significant alignments: (Bits) Value
Q46339 Formyltetrahydrofolate deformylase [Corynebacterium sp. (s... 296 6e-104
P9WHM3 Formyltetrahydrofolate deformylase [Mycobacterium tubercul... 222 1e-74
P9WHM2 Formyltetrahydrofolate deformylase [Mycobacterium tubercul... 222 1e-74
P0A5T7 Formyltetrahydrofolate deformylase [Mycobacterium bovis (s... 222 1e-74
Q55135 Formyltetrahydrofolate deformylase [Synechocystis sp. (str... 220 3e-74
O34990 Formyltetrahydrofolate deformylase [Bacillus subtilis (str... 218 5e-73
P37051 Formyltetrahydrofolate deformylase [Escherichia coli (stra... 196 1e-64
P0A440 Formyltetrahydrofolate deformylase [Escherichia coli O6:H1... 194 4e-64
P0A441 Formyltetrahydrofolate deformylase [Shigella flexneri] 194 4e-64
Q03432 Formyltetrahydrofolate deformylase [Haemophilus influenzae... 184 4e-60
F4JP46 Formyltetrahydrofolate deformylase 2, mitochondrial [Arabi... 177 8e-57
Q93YQ3 Formyltetrahydrofolate deformylase 1, mitochondrial [Arabi... 169 7e-54
Q5HH12 Phosphoribosylglycinamide formyltransferase [Staphylococcu... 85.5 2e-23
P08179 Phosphoribosylglycinamide formyltransferase [Escherichia c... 82.4 5e-22
P22102 Phosphoribosylamine--glycine ligase / Phosphoribosylformyl... 85.5 9e-22
Q64737 Phosphoribosylamine--glycine ligase / Phosphoribosylformyl... 84.0 3e-21
P21872 Phosphoribosylamine--glycine ligase / Phosphoribosylformyl... 83.6 4e-21
>Q46339 Formyltetrahydrofolate deformylase [Corynebacterium sp.
(strain P-1)]
Length=286
Score = 296 bits (757), Expect = 6e-104
Identities = 147/281 (52%), Positives = 198/281 (70%), Gaps = 0/281 (0%)
Query 8 QYVLKISCPAASGIVAAVSNCLAGNDCYISEMAQYDDEITGRFFSRIVFRFNEGQGDLEL 67
++VL + CP GIV AV+ L + I E+ QYDD GR F R+ F + L+
Sbjct 6 RHVLTLQCPEGIGIVHAVTGFLVRHQRTIVELKQYDDMSAGRLFLRVDFAGDSAPDLLDA 65
Query 68 LKEKFADVTAKFAMKADFYEKKNPMKVLIMVSKFDHCLLNLLYRHHKGELDFQITAIVSN 127
L+ +F++V AKF M E+ KVLIMVSKF+HCL +LL+R H G+L ++ + SN
Sbjct 66 LRSEFSEVAAKFDMDWQLRERGQKTKVLIMVSKFEHCLQDLLFRMHSGDLPIEVVGVASN 125
Query 128 HLDLRAIAEREGIRFIYLPVSKDTKQQQEQELLKIVDETKTELVILARYMQILSNNLCTQ 187
H D R++ E GI F ++P+SKDTK + E LL+++D+T ELV+LARYMQ+LS++L ++
Sbjct 126 HPDHRSLVEWYGIGFHHIPISKDTKPRAEAALLELIDQTGAELVVLARYMQVLSDHLASE 185
Query 188 LSGRAINIHHSFLPGFKGAKPYHQAFERGVKLIGATAHFVTSDLDEGPIIEQEVQRVDHA 247
L+G+ INIHHSFLP FKGAKPYHQA+ERGVK +GATAH+V S+LDEGPII Q+V VDH
Sbjct 186 LTGKTINIHHSFLPSFKGAKPYHQAWERGVKTVGATAHYVNSELDEGPIIAQQVVEVDHT 245
Query 248 YMPDDLVSVGRDTETVALSKAVKYFVEHRVFMNDDRTVVFK 288
Y P DLV+ GRD+E ALS AV++ E RVF+ +RTVV +
Sbjct 246 YGPQDLVAAGRDSECKALSNAVRWHCEGRVFLYGNRTVVLR 286
>P9WHM3 Formyltetrahydrofolate deformylase [Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv)]
Length=310
Score = 222 bits (565), Expect = 1e-74
Identities = 124/279 (44%), Positives = 168/279 (60%), Gaps = 3/279 (1%)
Query 11 LKISCPAASGIVAAVSNCLAGNDCYISEMAQYDDEITG-RFFSRIVFRFNEGQGDLELLK 69
L + C GI+AAVS LA I + Q+ G F R +F ++ L+
Sbjct 33 LLLRCHDRPGIIAAVSTFLARAGANIISLDQHSTAPEGGTFLQRAIFHLPGLTAAVDELQ 92
Query 70 EKFADVTA-KFAMKADFYEKKNPMKVLIMVSKFDHCLLNLLYRHHKGELDFQITAIVSNH 128
F A KF + F E P +V IM S DHCLL+LL+R+ +GEL+ + +++NH
Sbjct 93 RDFGSTVADKFGIDYRFAEAAKPKRVAIMASTEDHCLLDLLWRNRRGELEMSVVMVIANH 152
Query 129 LDLRAIAEREGIRFIYLPVSKDTKQQQEQELLKIVDETKTELVILARYMQILSNNLCTQL 188
DL A G+ FI++P ++DT+ + EQ L+++ +LV+LARYMQILS +
Sbjct 153 PDLAAHVRPFGVPFIHIPATRDTRTEAEQRQLQLLSGN-VDLVVLARYMQILSPGFLEAI 211
Query 189 SGRAINIHHSFLPGFKGAKPYHQAFERGVKLIGATAHFVTSDLDEGPIIEQEVQRVDHAY 248
INIHHSFLP F GA PY +A ERGVKLIGATAH+VT LDEGPIIEQ+V RVDH +
Sbjct 212 GCPLINIHHSFLPAFTGAAPYQRARERGVKLIGATAHYVTEVLDEGPIIEQDVVRVDHTH 271
Query 249 MPDDLVSVGRDTETVALSKAVKYFVEHRVFMNDDRTVVF 287
DDLV VG D E LS+AV + + RV ++ ++T+VF
Sbjct 272 TVDDLVRVGADVERAVLSRAVLWHCQDRVIVHHNQTIVF 310
>P9WHM2 Formyltetrahydrofolate deformylase [Mycobacterium tuberculosis
(strain CDC 1551 / Oshkosh)]
Length=310
Score = 222 bits (565), Expect = 1e-74
Identities = 124/279 (44%), Positives = 168/279 (60%), Gaps = 3/279 (1%)
Query 11 LKISCPAASGIVAAVSNCLAGNDCYISEMAQYDDEITG-RFFSRIVFRFNEGQGDLELLK 69
L + C GI+AAVS LA I + Q+ G F R +F ++ L+
Sbjct 33 LLLRCHDRPGIIAAVSTFLARAGANIISLDQHSTAPEGGTFLQRAIFHLPGLTAAVDELQ 92
Query 70 EKFADVTA-KFAMKADFYEKKNPMKVLIMVSKFDHCLLNLLYRHHKGELDFQITAIVSNH 128
F A KF + F E P +V IM S DHCLL+LL+R+ +GEL+ + +++NH
Sbjct 93 RDFGSTVADKFGIDYRFAEAAKPKRVAIMASTEDHCLLDLLWRNRRGELEMSVVMVIANH 152
Query 129 LDLRAIAEREGIRFIYLPVSKDTKQQQEQELLKIVDETKTELVILARYMQILSNNLCTQL 188
DL A G+ FI++P ++DT+ + EQ L+++ +LV+LARYMQILS +
Sbjct 153 PDLAAHVRPFGVPFIHIPATRDTRTEAEQRQLQLLSGN-VDLVVLARYMQILSPGFLEAI 211
Query 189 SGRAINIHHSFLPGFKGAKPYHQAFERGVKLIGATAHFVTSDLDEGPIIEQEVQRVDHAY 248
INIHHSFLP F GA PY +A ERGVKLIGATAH+VT LDEGPIIEQ+V RVDH +
Sbjct 212 GCPLINIHHSFLPAFTGAAPYQRARERGVKLIGATAHYVTEVLDEGPIIEQDVVRVDHTH 271
Query 249 MPDDLVSVGRDTETVALSKAVKYFVEHRVFMNDDRTVVF 287
DDLV VG D E LS+AV + + RV ++ ++T+VF
Sbjct 272 TVDDLVRVGADVERAVLSRAVLWHCQDRVIVHHNQTIVF 310
>P0A5T7 Formyltetrahydrofolate deformylase [Mycobacterium bovis
(strain ATCC BAA-935 / AF2122/97)]
Length=310
Score = 222 bits (565), Expect = 1e-74
Identities = 124/279 (44%), Positives = 168/279 (60%), Gaps = 3/279 (1%)
Query 11 LKISCPAASGIVAAVSNCLAGNDCYISEMAQYDDEITG-RFFSRIVFRFNEGQGDLELLK 69
L + C GI+AAVS LA I + Q+ G F R +F ++ L+
Sbjct 33 LLLRCHDRPGIIAAVSTFLARAGANIISLDQHSTAPEGGTFLQRAIFHLPGLTAAVDELQ 92
Query 70 EKFADVTA-KFAMKADFYEKKNPMKVLIMVSKFDHCLLNLLYRHHKGELDFQITAIVSNH 128
F A KF + F E P +V IM S DHCLL+LL+R+ +GEL+ + +++NH
Sbjct 93 RDFGSTVADKFGIDYRFAEAAKPKRVAIMASTEDHCLLDLLWRNRRGELEMSVVMVIANH 152
Query 129 LDLRAIAEREGIRFIYLPVSKDTKQQQEQELLKIVDETKTELVILARYMQILSNNLCTQL 188
DL A G+ FI++P ++DT+ + EQ L+++ +LV+LARYMQILS +
Sbjct 153 PDLAAHVRPFGVPFIHIPATRDTRTEAEQRQLQLLSGN-VDLVVLARYMQILSPGFLEAI 211
Query 189 SGRAINIHHSFLPGFKGAKPYHQAFERGVKLIGATAHFVTSDLDEGPIIEQEVQRVDHAY 248
INIHHSFLP F GA PY +A ERGVKLIGATAH+VT LDEGPIIEQ+V RVDH +
Sbjct 212 GCPLINIHHSFLPAFTGAAPYQRARERGVKLIGATAHYVTEVLDEGPIIEQDVVRVDHTH 271
Query 249 MPDDLVSVGRDTETVALSKAVKYFVEHRVFMNDDRTVVF 287
DDLV VG D E LS+AV + + RV ++ ++T+VF
Sbjct 272 TVDDLVRVGADVERAVLSRAVLWHCQDRVIVHHNQTIVF 310
>Q55135 Formyltetrahydrofolate deformylase [Synechocystis sp.
(strain PCC 6803 / Kazusa)]
Length=284
Score = 220 bits (561), Expect = 3e-74
Identities = 117/277 (42%), Positives = 173/277 (62%), Gaps = 1/277 (0%)
Query 11 LKISCPAASGIVAAVSNCLAGNDCYISEMAQYDDEITGRFFSRIVFRFNEGQGDLELLKE 70
L +SCP GIVA ++ + N I Q+ D +G F +R+ ++ + + L
Sbjct 8 LLVSCPDQPGIVAQIAQFIYQNQGNIIHADQHTDFSSGLFLNRVEWQLDNFRLSRPELLS 67
Query 71 KFADVTAKFAMKADFYEKKNPMKVLIMVSKFDHCLLNLLYRHHKGELDFQITAIVSNHLD 130
++ + + + ++ + VSK DHCLL++L+R GEL +I I+SNH D
Sbjct 68 AWSQLAEQLQATWQIHFSDQLPRLALWVSKQDHCLLDILWRWRSGELRCEIPLIISNHPD 127
Query 131 LRAIAEREGIRFIYLPVSKDTKQQQEQELLKIVDETKTELVILARYMQILSNNLCTQLSG 190
L++IA++ GI F LP++K+ K QE L ++ + + +LV+LA+Y+QIL+ + Q
Sbjct 128 LKSIADQFGIDFHCLPITKENKLAQETAELALLKQYQIDLVVLAKYLQILTTDFVVQFPN 187
Query 191 RAINIHHSFLPGFKGAKPYHQAFERGVKLIGATAHFVTSDLDEGPIIEQEVQRVDHAYMP 250
INIHHSFLP F GA PYH+A ERGVK+IGATAH+ T+ LDEGPIIEQ+V RV H
Sbjct 188 -IINIHHSFLPAFPGANPYHRAHERGVKIIGATAHYATAQLDEGPIIEQDVVRVSHRDNV 246
Query 251 DDLVSVGRDTETVALSKAVKYFVEHRVFMNDDRTVVF 287
DDL+ GRD E V L++AV+ ++HR+ + D+RTVVF
Sbjct 247 DDLIRKGRDLERVVLARAVRLHLQHRILVYDNRTVVF 283
>O34990 Formyltetrahydrofolate deformylase [Bacillus subtilis
(strain 168)]
Length=300
Score = 218 bits (554), Expect = 5e-73
Identities = 121/282 (43%), Positives = 174/282 (62%), Gaps = 1/282 (0%)
Query 7 DQYVLKISCPAASGIVAAVSNCLAGNDCYISEMAQYD-DEITGRFFSRIVFRFNEGQGDL 65
D+ L +SCP GIV+AVS L + I E QY D GRFF RI F +
Sbjct 18 DKGRLLVSCPDQPGIVSAVSAFLFEHGANIIESNQYTTDPEGGRFFLRIEFDCAGIREKK 77
Query 66 ELLKEKFADVTAKFAMKADFYEKKNPMKVLIMVSKFDHCLLNLLYRHHKGELDFQITAIV 125
L+ FA V KF M +V I VSK HCL L++ G L +I ++
Sbjct 78 SSLQAAFASVAEKFDMTWSLTLASELKRVAIFVSKELHCLHELIWEWQTGNLMAEIAVVI 137
Query 126 SNHLDLRAIAEREGIRFIYLPVSKDTKQQQEQELLKIVDETKTELVILARYMQILSNNLC 185
SNH + R + ER I F Y+ +KD + + E++ L+++++ ++++LARYMQIL+ +
Sbjct 138 SNHEEARELVERLNIPFHYMKANKDIRAEVEKKQLELLEQYDVDVIVLARYMQILTPDFV 197
Query 186 TQLSGRAINIHHSFLPGFKGAKPYHQAFERGVKLIGATAHFVTSDLDEGPIIEQEVQRVD 245
+ R INIHHSFLP F GA PY +A+ERGVKLIGAT+H+VT+DLDEGPIIEQ+++RVD
Sbjct 198 SAHPNRIINIHHSFLPAFIGANPYKRAYERGVKLIGATSHYVTNDLDEGPIIEQDIERVD 257
Query 246 HAYMPDDLVSVGRDTETVALSKAVKYFVEHRVFMNDDRTVVF 287
H + L ++GR E L++AVK+ +E RV +++++T+VF
Sbjct 258 HRDNAEALKNIGRTIERSVLARAVKWHLEDRVIVHENKTIVF 299
>P37051 Formyltetrahydrofolate deformylase [Escherichia coli (strain
K12)]
Length=280
Score = 196 bits (497), Expect = 1e-64
Identities = 110/282 (39%), Positives = 169/282 (60%), Gaps = 15/282 (5%)
Query 10 VLKISCPAASGIVAAVSNCLAGNDCYISEMAQYDDEITGRFFSRIVFR--FNEGQGDLEL 67
VL+ CP G++A ++N ++ I + ++ D TGRFF R FN D L
Sbjct 8 VLRTICPDQKGLIARITNICYKHELNIVQNNEFVDHRTGRFFMRTELEGIFN----DSTL 63
Query 68 LKEKFADVTAKFAMKADFYEKKNPM---KVLIMVSKFDHCLLNLLYRHHKGELDFQITAI 124
L AD+ + A+ + NP +++I+V+K HCL +LL + + G LD +I A+
Sbjct 64 L----ADLDS--ALPEGSVRELNPAGRRRIVILVTKEAHCLGDLLMKANYGGLDVEIAAV 117
Query 125 VSNHLDLRAIAEREGIRFIYLPVSKDTKQQQEQELLKIVDETKTELVILARYMQILSNNL 184
+ NH LR++ ER I F + T+ + +Q++ +D + + V+LA+YM++L+
Sbjct 118 IGNHDTLRSLVERFDIPFELVSHEGLTRNEHDQKMADAIDAYQPDYVVLAKYMRVLTPEF 177
Query 185 CTQLSGRAINIHHSFLPGFKGAKPYHQAFERGVKLIGATAHFVTSDLDEGPIIEQEVQRV 244
+ + INIHHSFLP F GA+PYHQA+ERGVK+IGATAH+V +LDEGPII Q+V V
Sbjct 178 VARFPNKIINIHHSFLPAFIGARPYHQAYERGVKIIGATAHYVNDNLDEGPIIMQDVIHV 237
Query 245 DHAYMPDDLVSVGRDTETVALSKAVKYFVEHRVFMNDDRTVV 286
DH Y +D++ GRD E LS+A+ + RVF+ +RT++
Sbjct 238 DHTYTAEDMMRAGRDVEKNVLSRALYKVLAQRVFVYGNRTII 279
>P0A440 Formyltetrahydrofolate deformylase [Escherichia coli O6:H1
(strain CFT073 / ATCC 700928 / UPEC)]
Length=280
Score = 194 bits (493), Expect = 4e-64
Identities = 109/282 (39%), Positives = 169/282 (60%), Gaps = 15/282 (5%)
Query 10 VLKISCPAASGIVAAVSNCLAGNDCYISEMAQYDDEITGRFFSRIVFR--FNEGQGDLEL 67
VL+ CP G++A ++N ++ I + ++ D TGRFF R FN D L
Sbjct 8 VLRTICPDQKGLIARITNICYKHELNIVQNNEFVDHRTGRFFMRTELEGIFN----DSTL 63
Query 68 LKEKFADVTAKFAMKADFYEKKNPM---KVLIMVSKFDHCLLNLLYRHHKGELDFQITAI 124
L AD+ + A+ + NP +++I+V+K HCL +LL + + G LD +I A+
Sbjct 64 L----ADLDS--ALPEGSVRELNPAGRRRIVILVTKEAHCLGDLLMKANYGGLDVEIAAV 117
Query 125 VSNHLDLRAIAEREGIRFIYLPVSKDTKQQQEQELLKIVDETKTELVILARYMQILSNNL 184
+ NH LR++ ER I F + ++ + +Q++ +D + + V+LA+YM++L+
Sbjct 118 IGNHDTLRSLVERFDIPFELVSHEGLSRNEHDQKMADAIDAYQPDYVVLAKYMRVLTPEF 177
Query 185 CTQLSGRAINIHHSFLPGFKGAKPYHQAFERGVKLIGATAHFVTSDLDEGPIIEQEVQRV 244
+ + INIHHSFLP F GA+PYHQA+ERGVK+IGATAH+V +LDEGPII Q+V V
Sbjct 178 VARFPNKIINIHHSFLPAFIGARPYHQAYERGVKIIGATAHYVNDNLDEGPIIMQDVIHV 237
Query 245 DHAYMPDDLVSVGRDTETVALSKAVKYFVEHRVFMNDDRTVV 286
DH Y +D++ GRD E LS+A+ + RVF+ +RT++
Sbjct 238 DHTYTAEDMMRAGRDVEKNVLSRALYKVLAQRVFVYGNRTII 279
>P0A441 Formyltetrahydrofolate deformylase [Shigella flexneri]
Length=280
Score = 194 bits (493), Expect = 4e-64
Identities = 109/282 (39%), Positives = 169/282 (60%), Gaps = 15/282 (5%)
Query 10 VLKISCPAASGIVAAVSNCLAGNDCYISEMAQYDDEITGRFFSRIVFR--FNEGQGDLEL 67
VL+ CP G++A ++N ++ I + ++ D TGRFF R FN D L
Sbjct 8 VLRTICPDQKGLIARITNICYKHELNIVQNNEFVDHRTGRFFMRTELEGIFN----DSTL 63
Query 68 LKEKFADVTAKFAMKADFYEKKNPM---KVLIMVSKFDHCLLNLLYRHHKGELDFQITAI 124
L AD+ + A+ + NP +++I+V+K HCL +LL + + G LD +I A+
Sbjct 64 L----ADLDS--ALPEGSVRELNPAGRRRIVILVTKEAHCLGDLLMKANYGGLDVEIAAV 117
Query 125 VSNHLDLRAIAEREGIRFIYLPVSKDTKQQQEQELLKIVDETKTELVILARYMQILSNNL 184
+ NH LR++ ER I F + ++ + +Q++ +D + + V+LA+YM++L+
Sbjct 118 IGNHDTLRSLVERFDIPFELVSHEGLSRNEHDQKMADAIDAYQPDYVVLAKYMRVLTPEF 177
Query 185 CTQLSGRAINIHHSFLPGFKGAKPYHQAFERGVKLIGATAHFVTSDLDEGPIIEQEVQRV 244
+ + INIHHSFLP F GA+PYHQA+ERGVK+IGATAH+V +LDEGPII Q+V V
Sbjct 178 VARFPNKIINIHHSFLPAFIGARPYHQAYERGVKIIGATAHYVNDNLDEGPIIMQDVIHV 237
Query 245 DHAYMPDDLVSVGRDTETVALSKAVKYFVEHRVFMNDDRTVV 286
DH Y +D++ GRD E LS+A+ + RVF+ +RT++
Sbjct 238 DHTYTAEDMMRAGRDVEKNVLSRALYKVLAQRVFVYGNRTII 279
>Q03432 Formyltetrahydrofolate deformylase [Haemophilus influenzae
(strain ATCC 51907 / DSM 11121 / KW20 / Rd)]
Length=278
Score = 184 bits (466), Expect = 4e-60
Identities = 100/284 (35%), Positives = 166/284 (58%), Gaps = 9/284 (3%)
Query 5 LVDQYVLKISCPAASGIVAAVSNCLAGNDCYISEMAQYDDEITGRFFSRIVFR--FNEGQ 62
++++ +L CP G++A ++N + I ++ D T FF R FNE
Sbjct 1 MIEKKILLTDCPDDKGLIAKITNICYKHQLNILHNNEFVDFETKHFFMRTELEGIFNEAT 60
Query 63 GDLELLKEKFADVTAKFAMKADFYEKKNPMKVLIMVSKFDHCLLNLLYRHHKGELDFQIT 122
LL++ + + + ++K +++I+V+K HCL ++L +++ G LD +I
Sbjct 61 ----LLEDLKYSLPEETNCRLIGTQRK---RIVILVTKEAHCLGDILMKNYYGALDVEIA 113
Query 123 AIVSNHLDLRAIAEREGIRFIYLPVSKDTKQQQEQELLKIVDETKTELVILARYMQILSN 182
A++ NH +LR + ER I F + T+ + ++ L + +DE + ++LA+YM++L+
Sbjct 114 AVIGNHDNLRELVERFNIPFHLVSHENLTRVEHDKLLAEKIDEYTPDYIVLAKYMRVLNP 173
Query 183 NLCTQLSGRAINIHHSFLPGFKGAKPYHQAFERGVKLIGATAHFVTSDLDEGPIIEQEVQ 242
+ R INIHHSFLP F GAKPY QA++RGVK+IGATAHF+ ++LD+GPII Q V
Sbjct 174 EFVARYPNRVINIHHSFLPAFIGAKPYQQAYKRGVKIIGATAHFINNELDQGPIIMQNVI 233
Query 243 RVDHAYMPDDLVSVGRDTETVALSKAVKYFVEHRVFMNDDRTVV 286
VDH Y + ++ GRD E LS+A+ + R+F+ ++TVV
Sbjct 234 NVDHTYNAEAMMRAGRDVEKTVLSRALDLALHDRIFVYKNKTVV 277
>F4JP46 Formyltetrahydrofolate deformylase 2, mitochondrial [Arabidopsis
thaliana]
Length=328
Score = 177 bits (448), Expect = 8e-57
Identities = 109/282 (39%), Positives = 149/282 (53%), Gaps = 13/282 (5%)
Query 15 CPAASGIVAAVSNCLAGNDCYISEMAQYDDEITGRFFSRIVFRFNEGQGDLELLKEKFAD 74
CP GIVA +S+C+A I + E F+SR F F+ + + E F
Sbjct 51 CPDVVGIVAKLSDCIAAKGGNILGYDVFVPENKNVFYSRSEFIFDPVKWPRRQMDEDFQT 110
Query 75 VTAKFAMKADFYEKKN---PMKVLIMVSKFDHCLLNLLYRHHKGELDFQITAIVSNH--- 128
+ KF+ + + K+ +++SK DHCL+ +L++ G+L IT ++SNH
Sbjct 111 IAQKFSALSSVVRVPSLDPKYKIALLLSKQDHCLVEMLHKWQDGKLPVDITCVISNHERA 170
Query 129 --LDLRAIAEREGIRFIYLPVSKDTKQQQEQELLKIVDETKTELVILARYMQILSNNLCT 186
+ +R GI + YLP + K E+E+L++V T + ++LARYMQ+LS N
Sbjct 171 PNTHVMRFLQRHGISYHYLPTTDQNKI--EEEILELVKGT--DFLVLARYMQLLSGNFLK 226
Query 187 QLSGRAINIHHSFLPGFKGAKPYHQAFERGVKLIGATAHFVTSDLDEGPIIEQEVQRVDH 246
INIHH LP FKG P QAF+ GVKLIGAT HFVT +LD GPIIEQ V+RV H
Sbjct 227 GYGKDVINIHHGLLPSFKGRNPVKQAFDAGVKLIGATTHFVTEELDSGPIIEQMVERVSH 286
Query 247 AYMPDDLVSVGRDTETVALSKAVKYFVEHRVF-MNDDRTVVF 287
V D E L KA+K + E RV RTVVF
Sbjct 287 RDNLRSFVQKSEDLEKKCLMKAIKSYCELRVLPYGTQRTVVF 328
>Q93YQ3 Formyltetrahydrofolate deformylase 1, mitochondrial [Arabidopsis
thaliana]
Length=323
Score = 169 bits (428), Expect = 7e-54
Identities = 104/282 (37%), Positives = 151/282 (54%), Gaps = 13/282 (5%)
Query 15 CPAASGIVAAVSNCLAGNDCYISEMAQYDDEITGRFFSRIVFRFNEGQGDLELLKEKFAD 74
C A GIVA +S+C+A I + E F+SR F F+ + + E F
Sbjct 46 CQDAVGIVAKLSDCIAAKGGNILGYDVFVPENNNVFYSRSEFIFDPVKWPRSQVDEDFQT 105
Query 75 VTAKFAMKADFYEKKN---PMKVLIMVSKFDHCLLNLLYRHHKGELDFQITAIVSNH--- 128
+ ++ + K+ +++SK DHCL+ +L++ G+L IT ++SNH
Sbjct 106 IAQRYGALNSVVRVPSIDPKYKIALLLSKQDHCLVEMLHKWQDGKLPVDITCVISNHERA 165
Query 129 --LDLRAIAEREGIRFIYLPVSKDTKQQQEQELLKIVDETKTELVILARYMQILSNNLCT 186
+ ER GI + Y+ +K+ K+ E ++L++V +T + ++LARYMQILS N
Sbjct 166 SNTHVMRFLERHGIPYHYVSTTKENKR--EDDILELVKDT--DFLVLARYMQILSGNFLK 221
Query 187 QLSGRAINIHHSFLPGFKGAKPYHQAFERGVKLIGATAHFVTSDLDEGPIIEQEVQRVDH 246
INIHH LP FKG P QAF+ GVKLIGAT+HFVT +LD GPIIEQ V+ V H
Sbjct 222 GYGKDVINIHHGLLPSFKGGYPAKQAFDAGVKLIGATSHFVTEELDSGPIIEQMVESVSH 281
Query 247 AYMPDDLVSVGRDTETVALSKAVKYFVEHRVF-MNDDRTVVF 287
V D E L++A+K + E RV ++TVVF
Sbjct 282 RDNLRSFVQKSEDLEKKCLTRAIKSYCELRVLPYGTNKTVVF 323
>Q5HH12 Phosphoribosylglycinamide formyltransferase [Staphylococcus
aureus (strain COL)]
Length=188
Score = 85.5 bits (210), Expect = 2e-23
Identities = 51/152 (34%), Positives = 84/152 (55%), Gaps = 4/152 (3%)
Query 92 MKVLIMVSKFDHCLLNLLYRHHKGELD-FQITAIVSNHLDLRAI--AEREGIR-FIYLPV 147
+K+ I S N++ G+L+ ++TA+ ++H + I A++ I +I P
Sbjct 2 VKIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQNAFCIDRAKKHDIPVYINEPK 61
Query 148 SKDTKQQQEQELLKIVDETKTELVILARYMQILSNNLCTQLSGRAINIHHSFLPGFKGAK 207
D+K EQ L+ +++E K E +ILA YM+++ +L G+ +NIH S LP +KG
Sbjct 62 QFDSKAAYEQHLVTLLNEDKVEWIILAGYMRLIGPDLLASFEGKILNIHPSLLPKYKGID 121
Query 208 PYHQAFERGVKLIGATAHFVTSDLDEGPIIEQ 239
QA+ G + G+T H+V S +D G IIEQ
Sbjct 122 AIGQAYHSGDTITGSTVHYVDSGMDTGEIIEQ 153
>P08179 Phosphoribosylglycinamide formyltransferase [Escherichia
coli (strain K12)]
Length=212
Score = 82.4 bits (202), Expect = 5e-22
Identities = 54/194 (28%), Positives = 98/194 (51%), Gaps = 3/194 (2%)
Query 92 MKVLIMVSKFDHCLLNLLYRHHKGELDFQITAIVSNHLDLRAI--AEREGIRFIYLPVSK 149
M +++++S L ++ ++ + A+ SN D + A + GI L S
Sbjct 1 MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASA 60
Query 150 -DTKQQQEQELLKIVDETKTELVILARYMQILSNNLCTQLSGRAINIHHSFLPGFKGAKP 208
D+++ ++EL+ +D ++V+LA +M+ILS + +GR +NIH S LP + G
Sbjct 61 FDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHT 120
Query 209 YHQAFERGVKLIGATAHFVTSDLDEGPIIEQEVQRVDHAYMPDDLVSVGRDTETVALSKA 268
+ QA E G + G + HFVT +LD GP+I Q V DD+ + + E
Sbjct 121 HRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLV 180
Query 269 VKYFVEHRVFMNDD 282
+ +F + R+ M+++
Sbjct 181 ISWFADGRLKMHEN 194
>P22102 Phosphoribosylamine--glycine ligase / Phosphoribosylformylglycinamidine
cyclo-ligase / Phosphoribosylglycinamide formyltransferase
[Homo sapiens]
Length=1010
Score = 85.5 bits (210), Expect = 9e-22
Identities = 64/197 (32%), Positives = 99/197 (50%), Gaps = 19/197 (10%)
Query 86 YEKKNPMKVLIMVSKFDHCLLNLLYRHHKGELDFQITAIVSNHLDLRAI--AEREGI--R 141
+EKK +V +++S L L+ + QI ++SN + + AER GI R
Sbjct 803 FEKKKA-RVAVLISGTGSNLQALIDSTREPNSSAQIDIVISNKAAVAGLDKAERAGIPTR 861
Query 142 FIYLPVSKDTKQQQEQELLKIVDETKTELVILARYMQILSNNLCTQLSGRAINIHHSFLP 201
I + K+ + + + + +++E ++V LA +M+ILS + +G+ +NIH S LP
Sbjct 862 VINHKLYKN-RVEFDSAIDLVLEEFSIDIVCLAGFMRILSGPFVQKWNGKMLNIHPSLLP 920
Query 202 GFKGAKPYHQAFERGVKLIGATAHFVTSDLDEGPIIEQEVQRVDHAYMPDDLVSVGRDTE 261
FKG+ + QA E GV + G T HFV D+D G II QE V V R
Sbjct 921 SFKGSNAHEQALETGVTVTGCTVHFVAEDVDAGQIILQEA------------VPVKRGDT 968
Query 262 TVALSKAVKYFVEHRVF 278
LS+ VK EH++F
Sbjct 969 VATLSERVK-LAEHKIF 984
>Q64737 Phosphoribosylamine--glycine ligase / Phosphoribosylformylglycinamidine
cyclo-ligase / Phosphoribosylglycinamide formyltransferase
[Mus musculus]
Length=1010
Score = 84.0 bits (206), Expect = 3e-21
Identities = 61/202 (30%), Positives = 99/202 (49%), Gaps = 18/202 (9%)
Query 81 MKADFYEKKNPMKVLIMVSKFDHCLLNLLYRHHKGELDFQITAIVSNHLDLRAI--AERE 138
+K++F ++ +V +++S L L+ + I ++SN + + AER
Sbjct 797 LKSNFPVQQKKARVAVLISGTGSNLQALIDSTRDPKSSSHIVLVISNKAAVAGLDRAERA 856
Query 139 GI--RFIYLPVSKDTKQQQEQELLKIVDETKTELVILARYMQILSNNLCTQLSGRAINIH 196
GI R I + K+ + + + + +++E ++V LA +M+ILS + G+ +NIH
Sbjct 857 GIPTRVINHKLYKN-RVEFDNAVDHVLEEFSVDIVCLAGFMRILSGPFVRKWDGKMLNIH 915
Query 197 HSFLPGFKGAKPYHQAFERGVKLIGATAHFVTSDLDEGPIIEQEVQRVDHAYMPDDLVSV 256
S LP FKG+ + Q E GV + G T HFV D+D G II QE V V
Sbjct 916 PSLLPSFKGSNAHEQVLEAGVTITGCTVHFVAEDVDAGQIILQEA------------VPV 963
Query 257 GRDTETVALSKAVKYFVEHRVF 278
R LS+ VK EH++F
Sbjct 964 RRGDTVATLSERVK-VAEHKIF 984
Score = 19.6 bits (39), Expect = 2.0
Identities = 8/26 (31%), Positives = 15/26 (58%), Gaps = 0/26 (0%)
Query 196 HHSFLPGFKGAKPYHQAFERGVKLIG 221
+HS + +K Y A+ +GV++ G
Sbjct 331 NHSAVTVVMASKGYPGAYTKGVEITG 356
>P21872 Phosphoribosylamine--glycine ligase / Phosphoribosylformylglycinamidine
cyclo-ligase / Phosphoribosylglycinamide formyltransferase
[Gallus gallus]
Length=1003
Score = 83.6 bits (205), Expect = 4e-21
Identities = 63/192 (33%), Positives = 97/192 (51%), Gaps = 16/192 (8%)
Query 90 NPMKVLIMVSKFDHCLLNLLYRHHKGELDFQITAIVSNHLDLRAI--AEREGIRFIYLPV 147
N +KV +++S L L+ K +I +VSN + + AER GI +
Sbjct 802 NKVKVAVLISGTGTNLEALINSTKKPTSFAEIVLVVSNKAGVEGLRKAERAGIPTRVIDH 861
Query 148 SK-DTKQQQEQELLKIVDETKTELVILARYMQILSNNLCTQLSGRAINIHHSFLPGFKGA 206
+ ++ + + + ++++E EL+ LA +M+ILS + G+ +NIH S LP FKGA
Sbjct 862 KQYGSRTEFDSAVDRVLEEFSVELICLAGFMRILSGPFVKKWEGKILNIHPSLLPSFKGA 921
Query 207 KPYHQAFERGVKLIGATAHFVTSDLDEGPIIEQEVQRVDHAYMPDDLVSVGRDTETVALS 266
+ E GV++ G T HFV ++D G II QE +P V +G ET LS
Sbjct 922 NAHKLVLEAGVRVTGCTVHFVAEEVDAGAIIFQEA-------VP---VKIGDTVET--LS 969
Query 267 KAVKYFVEHRVF 278
+ VK EHR F
Sbjct 970 ERVKE-AEHRAF 980
Lambda K H a alpha
0.325 0.139 0.403 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1488416
Database: 4c45e3182855df64718d7a592c597c61.SwissProt.fasta
Posted date: May 8, 2024 10:13 AM
Number of letters in database: 6,992
Number of sequences in database: 17
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
Loading
Data ...
