BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 8e3b3e160857ad9d334e6a2510b4f137.SwissProt.fasta
21 sequences; 25,778 total letters
Query= ACIAD2612
Length=1279
Score E
Sequences producing significant alignments: (Bits) Value
Q4ZX02 Phosphoribosylformylglycinamidine synthase [Pseudomonas sy... 1488 0.0
Q48LX3 Phosphoribosylformylglycinamidine synthase [Pseudomonas sa... 1485 0.0
Q886W6 Phosphoribosylformylglycinamidine synthase [Pseudomonas sy... 1484 0.0
Q3KHL4 Phosphoribosylformylglycinamidine synthase [Pseudomonas fl... 1480 0.0
Q8DF81 Phosphoribosylformylglycinamidine synthase [Vibrio vulnifi... 1471 0.0
Q4KHS6 Phosphoribosylformylglycinamidine synthase [Pseudomonas fl... 1469 0.0
Q32D15 Phosphoribosylformylglycinamidine synthase [Shigella dysen... 1467 0.0
P15254 Phosphoribosylformylglycinamidine synthase [Escherichia co... 1467 0.0
Q8XA46 Phosphoribosylformylglycinamidine synthase [Escherichia co... 1467 0.0
Q8FF26 Phosphoribosylformylglycinamidine synthase [Escherichia co... 1467 0.0
Q0TET1 Phosphoribosylformylglycinamidine synthase [Escherichia co... 1466 0.0
Q1R8H7 Phosphoribosylformylglycinamidine synthase [Escherichia co... 1466 0.0
P74881 Phosphoribosylformylglycinamidine synthase [Salmonella typ... 1443 0.0
O14228 Phosphoribosylformylglycinamidine synthase [Schizosaccharo... 1157 0.0
Q9M8D3 Probable phosphoribosylformylglycinamidine synthase, chlor... 773 0.0
O15067 Phosphoribosylformylglycinamidine synthase [Homo sapiens] 720 0.0
P35421 Phosphoribosylformylglycinamidine synthase [Drosophila mel... 701 0.0
P11282 Probable membrane antigen 75 [Saimiriine herpesvirus 2 (st... 163 3e-43
Q5SMH8 Phosphoribosylformylglycinamidine synthase subunit PurL [T... 154 3e-41
P26500 Phosphoribosylformylglycinamidine synthase subunit PurL [M... 152 2e-40
P9WHL7 Phosphoribosylformylglycinamidine synthase subunit PurL [M... 150 1e-39
>Q4ZX02 Phosphoribosylformylglycinamidine synthase [Pseudomonas
syringae pv. syringae (strain B728a)]
Length=1298
Score = 1488 bits (3852), Expect = 0.0
Identities = 766/1304 (59%), Positives = 953/1304 (73%), Gaps = 34/1304 (3%)
Query 1 MFIVAGAPAHSSFKKAQLLTRLSS-ISSVQSFDSQWVYLFD--QALNEQQHQSALQLLND 57
M I+ GAPA S+F+ ++LL +L +S+V +++ + D L ++ Q +LL
Sbjct 1 MLILRGAPALSAFRHSKLLEQLKQKVSAVSGLYAEFAHFADVNDVLTSEEQQVLDRLLKY 60
Query 58 GSSFELRQAATDEIQVLVTPRIGTISPWSSKATDIFKNCN-TPIHRLERGILFTLKGMSE 116
G S +++ + LV PR GTISPWSSKA+DI +NC + I RLERGI F ++G
Sbjct 61 GPSVPVQEPSGRLF--LVLPRFGTISPWSSKASDIARNCGLSKIQRLERGIAFYVEGQFS 118
Query 117 MTNE--VKQALHDRMTETVFAEIDSANALFLETSPKPLNSIDILGEGKAALVKANNEFGF 174
T + +LHDRMT+ V +++ A LF PKPL ++DILG G+AAL KAN E G
Sbjct 119 ETEAQAIADSLHDRMTQLVLGDLEQAANLFSHAQPKPLTAVDILGGGRAALEKANVELGL 178
Query 175 ALSEQEIDYLTDAFTQLGRNPNDIELMMFAQANSEHCRHKIFGSEWTIDGEVQPLSLFQM 234
AL+E EIDYL +F LGRNP+DIELMMFAQANSEHCRHKIF + W IDG+ Q SLF M
Sbjct 179 ALAEDEIDYLITSFNGLGRNPHDIELMMFAQANSEHCRHKIFNASWDIDGQSQEKSLFGM 238
Query 235 IKNTYKESPDEVLSAYKDNASVIVGYDTQRFYPKKDNDTGHYIYKYKSQAAHILMKVETH 294
IKNTY+ + VLSAYKDNASVIVG RF+P D +T Y + HILMKVETH
Sbjct 239 IKNTYQMHSEGVLSAYKDNASVIVGNVAGRFFP--DPETRQY--GAVQEPVHILMKVETH 294
Query 295 NHPTAISPFAGAATGSGGEIRDEGATGRGGKPKAGLTGFTVSNLNIPGFEQPWEENYGKP 354
NHPTAI+PF GAATGSGGEIRDEGATGRG KPKAGLTGFTVSNL IPGF QPWE YGKP
Sbjct 295 NHPTAIAPFPGAATGSGGEIRDEGATGRGAKPKAGLTGFTVSNLQIPGFVQPWEVPYGKP 354
Query 355 SRMASPLQIMIEGPLGGAAFNNEFGRPALNGYFRTFEQNVN----GEVKGFHKPIMIAGG 410
R+ + L IMIEGPLGGAAFNNEFGRPAL GYFRTFEQ++ EV+G+HKPIM+AGG
Sbjct 355 ERIVTALDIMIEGPLGGAAFNNEFGRPALTGYFRTFEQSITTPHGDEVRGYHKPIMLAGG 414
Query 411 YGNIRPDHVEKDAIQPGDLLIVLGGPAMLIGLGGGAASSVDSGTMGESLDFASVQRENPE 470
GNIR DHV+K I G LIVLGGPAMLIGLGGGAASS+ +GT LDFASVQRENPE
Sbjct 415 MGNIREDHVQKGEITVGSKLIVLGGPAMLIGLGGGAASSMATGTSSADLDFASVQRENPE 474
Query 471 MERRCQEVIDTCWRLEDFNPIVSVHDVGAGGLSNAMPELVNDHELGAILNLRKIPSLEPG 530
MERRCQEVID CW+L D NPI +HDVGAGGLSNA PELVND + G LR +P+ EPG
Sbjct 475 MERRCQEVIDRCWQLGDRNPISFIHDVGAGGLSNAFPELVNDGDRGGRFELRNVPNDEPG 534
Query 531 MSPMEIWSNEAQERYVLAIRPESLAQFEEICARERCPFAVLGEATEARHLTVEDPLFENN 590
M+P+EIWSNE+QERYVLA+ E +F+ IC RERCPFAV+GEAT LTV D F N+
Sbjct 535 MAPLEIWSNESQERYVLAVGVEDFERFKAICERERCPFAVVGEATAEPQLTVTDSHFGNS 594
Query 591 AVDIPMQVMLGGTPRMQRSYESIEREGTPFDTTQIDLKDAIFRVLKNPTVASKSFLITIG 650
VD+P++V+LG PRM RS E G FD + +D+++++ RVL++P VASKSFLITIG
Sbjct 595 PVDMPLEVLLGKAPRMHRSVAREEEIGDDFDPSTLDIEESVQRVLRHPAVASKSFLITIG 654
Query 651 DRSITGMVARDQMVGPWQVPVADAAVTTTSLQGYTGEAMAMGERPPVALLNPAASARLAV 710
DRSITG+VARDQMVGPWQVPVAD AVT TS TGEAMAMGER P+ALL+ AS R+A+
Sbjct 655 DRSITGLVARDQMVGPWQVPVADCAVTATSFDVNTGEAMAMGERTPLALLDAPASGRMAI 714
Query 711 AEAITNIASANIEQIGDIKLSANWMAAAGQKGEDQALFEGVKAIGMEMCPALGIAIPVGK 770
E +TNIA++ IE++ DIKLSANWM+AAG GED L++ VKA+GME+CP LGI IPVGK
Sbjct 715 GETLTNIAASLIEKLSDIKLSANWMSAAGHPGEDARLYDTVKAVGMELCPELGITIPVGK 774
Query 771 DSLSMRTTWNDDGEDKAVTSPMSGVITAFAPVSDVRKTLTPELKKFDESV--LVRIDLSK 828
DS+SM+T W+D+G +K+VTSP+S ++T FAPV D+R+TLTPEL + D+ + L+ IDL +
Sbjct 775 DSMSMKTRWSDEGTEKSVTSPLSLIVTGFAPVVDIRQTLTPEL-RMDKGITDLILIDLGR 833
Query 829 GQFRLGASILTQVYKAIGTVTPDVDSFDDLKAFFALVQDWNNRSLIQAYHDIGDGGLLAT 888
GQ R+GASIL Q + +G V PDVD +DLKAFFA++Q N+ I +YHD DGGLL +
Sbjct 834 GQNRMGASILAQTHGKLGRVAPDVDDAEDLKAFFAVIQGLNSDGHILSYHDRSDGGLLVS 893
Query 889 VAEMMFASRLGVAFEQQSIES--------LFAEEIGAVVQLKAADWDAVQAEIAASGLKD 940
EM FA G+ + LF EE+GAV+Q++ V A+ +A+GL+D
Sbjct 894 TLEMAFAGHCGLNLHLDGVADNVSELSAILFNEELGAVIQVRQDATPLVLAQFSAAGLED 953
Query 941 AISVVGRVNSSDQLSVN-----GLTFERAELQRAWAEVSHQIQRLRDNVETADQEFALIS 995
++V+G+ ++D++S++ + +R LQR WAE S+QIQRLRDN E ADQEF +
Sbjct 954 CVAVIGQPINNDEVSISFHGEPVFSGQRRLLQRQWAETSYQIQRLRDNAECADQEFDALL 1013
Query 996 DQNHKGLIAQATFDLNEPVEAPFIATR-RPNMAILREQGVNGHVEMAAAFDKVGFNTIDV 1054
++++ GL + FD+N+ + AP+I T RP +A+LREQGVNG VEMAAAFD+ GFN IDV
Sbjct 1014 EEDNPGLTVKLGFDVNDDIAAPYIKTGVRPQVAVLREQGVNGQVEMAAAFDRAGFNAIDV 1073
Query 1055 HMSDLLAGRVDLQDFEGLVACGGFSYGDVMGAGGGWAKSVLFNPKLRDQFESFFHRDSTF 1114
HMSD+LAGRVDL DF+G+VACGGFSYGDV+GAG GWAKS LFN + RD F+ FF R +F
Sbjct 1074 HMSDILAGRVDLNDFKGMVACGGFSYGDVLGAGEGWAKSALFNSRARDAFQGFFERSDSF 1133
Query 1115 SLGICNGCQMLSQLAPLIPGADAWPRFHRNVSEVFEARSVNVRVEKSVSVLLQDMQGSIL 1174
+LG+CNGCQMLS L LIPG++ WP F RN SE FEAR V+V++S S+ LQ M GS +
Sbjct 1134 TLGVCNGCQMLSNLHELIPGSEFWPHFVRNRSEQFEARVAMVQVQESASIFLQGMAGSRM 1193
Query 1175 PIAVAHGEGRV-VTTDAHLASLNANQQVTLRYVDSLGNPTQHYPLNPNGSPEAVTGVTSK 1233
PIA+AHGEG D L + + V LR+VD+ G T+ YP NPNGSP + G+T+
Sbjct 1194 PIAIAHGEGHAEFRNDDALLEADVSGTVALRFVDNHGKVTETYPANPNGSPRGIGGMTTL 1253
Query 1234 DGRATIMMPHPERNFRAIQHSWSPENWTEDGAWLRMFRNARKFI 1277
DGR TIMMPHPER FRA+Q+SW PE+W EDGAW+RMFRNAR ++
Sbjct 1254 DGRVTIMMPHPERVFRAVQNSWRPEDWNEDGAWMRMFRNARAWV 1297
>Q48LX3 Phosphoribosylformylglycinamidine synthase [Pseudomonas
savastanoi pv. phaseolicola (strain 1448A / Race 6)]
Length=1298
Score = 1485 bits (3844), Expect = 0.0
Identities = 765/1304 (59%), Positives = 951/1304 (73%), Gaps = 34/1304 (3%)
Query 1 MFIVAGAPAHSSFKKAQLLTRLSS-ISSVQSFDSQWVYLFD--QALNEQQHQSALQLLND 57
M I+ GAPA S+F+ ++LL +L +S+V +++ + D L ++ Q +LL
Sbjct 1 MLILRGAPALSAFRHSKLLEQLKQKVSAVSGLYAEFAHFADVNDVLTSEEQQVLDRLLKY 60
Query 58 GSSFELRQAATDEIQVLVTPRIGTISPWSSKATDIFKNCN-TPIHRLERGILFTLKGM-- 114
G S +++ + LV PR GTISPWSSKA+DI +NC T I R+ERGI F ++G
Sbjct 61 GPSVPVQEPSGRLF--LVLPRFGTISPWSSKASDIARNCGLTKIQRIERGIAFYVEGQFS 118
Query 115 SEMTNEVKQALHDRMTETVFAEIDSANALFLETSPKPLNSIDILGEGKAALVKANNEFGF 174
+ +LHDRMT+ V + + A +LF PKPL ++DILG G+AAL KAN E G
Sbjct 119 EAQAQAIADSLHDRMTQLVLGDHEQAASLFSHAQPKPLTAVDILGGGRAALEKANVELGL 178
Query 175 ALSEQEIDYLTDAFTQLGRNPNDIELMMFAQANSEHCRHKIFGSEWTIDGEVQPLSLFQM 234
AL+E EIDYL +F LGRNP+DIELMMFAQANSEHCRHKIF + W IDG+ Q SLF M
Sbjct 179 ALAEDEIDYLITSFNGLGRNPHDIELMMFAQANSEHCRHKIFNASWDIDGQSQEKSLFGM 238
Query 235 IKNTYKESPDEVLSAYKDNASVIVGYDTQRFYPKKDNDTGHYIYKYKSQAAHILMKVETH 294
IKNTY+ + VLSAYKDNASVIVG RF+P D +T Y + HILMKVETH
Sbjct 239 IKNTYQMHSEGVLSAYKDNASVIVGNVAGRFFP--DPETRQY--GAVQEPVHILMKVETH 294
Query 295 NHPTAISPFAGAATGSGGEIRDEGATGRGGKPKAGLTGFTVSNLNIPGFEQPWEENYGKP 354
NHPTAI+PF GAATGSGGEIRDEGATGRG KPKAGLTGFTVSNL IPGF QPWE YGKP
Sbjct 295 NHPTAIAPFPGAATGSGGEIRDEGATGRGAKPKAGLTGFTVSNLQIPGFVQPWEVPYGKP 354
Query 355 SRMASPLQIMIEGPLGGAAFNNEFGRPALNGYFRTFEQNVN----GEVKGFHKPIMIAGG 410
R+ + L IMIEGPLGGAAFNNEFGRPAL GYFRTFEQ++ EV+G+HKPIM+AGG
Sbjct 355 ERIVTALDIMIEGPLGGAAFNNEFGRPALTGYFRTFEQSITTPHGDEVRGYHKPIMLAGG 414
Query 411 YGNIRPDHVEKDAIQPGDLLIVLGGPAMLIGLGGGAASSVDSGTMGESLDFASVQRENPE 470
GNIR DHV+K I G LIVLGGPAMLIGLGGGAASS+ +GT LDFASVQRENPE
Sbjct 415 MGNIREDHVQKGEITVGSKLIVLGGPAMLIGLGGGAASSMATGTSSADLDFASVQRENPE 474
Query 471 MERRCQEVIDTCWRLEDFNPIVSVHDVGAGGLSNAMPELVNDHELGAILNLRKIPSLEPG 530
MERRCQEVID CW+L D NPI +HDVGAGGLSNA PELVND + G LR +P+ EPG
Sbjct 475 MERRCQEVIDRCWQLGDRNPISFIHDVGAGGLSNAFPELVNDGDRGGRFELRNVPNDEPG 534
Query 531 MSPMEIWSNEAQERYVLAIRPESLAQFEEICARERCPFAVLGEATEARHLTVEDPLFENN 590
M+P+EIWSNE+QERYVLA+ E +F+ IC RERCPFAV+GEAT LTV D F N+
Sbjct 535 MAPLEIWSNESQERYVLAVGVEDFDRFKAICERERCPFAVVGEATAEPQLTVTDSHFGNS 594
Query 591 AVDIPMQVMLGGTPRMQRSYESIEREGTPFDTTQIDLKDAIFRVLKNPTVASKSFLITIG 650
VD+P++V+LG PRM RS E G FD + +D+++++ RVL++P VASKSFLITIG
Sbjct 595 PVDMPLEVLLGKVPRMHRSVEREAEIGDDFDPSTLDIEESVQRVLRHPAVASKSFLITIG 654
Query 651 DRSITGMVARDQMVGPWQVPVADAAVTTTSLQGYTGEAMAMGERPPVALLNPAASARLAV 710
DRSITG+VARDQMVGPWQVPVAD AVT TS TGEAMAMGER P+ALL+ AS R+A+
Sbjct 655 DRSITGLVARDQMVGPWQVPVADCAVTATSFDVNTGEAMAMGERTPLALLDAPASGRMAI 714
Query 711 AEAITNIASANIEQIGDIKLSANWMAAAGQKGEDQALFEGVKAIGMEMCPALGIAIPVGK 770
E +TNIA++ IE++ DIKLSANWM+AAG GED L++ VKA+GME+CP LGI IPVGK
Sbjct 715 GETLTNIAASCIEKLSDIKLSANWMSAAGHPGEDARLYDTVKAVGMELCPELGITIPVGK 774
Query 771 DSLSMRTTWNDDGEDKAVTSPMSGVITAFAPVSDVRKTLTPELKKFDESV--LVRIDLSK 828
DS+SM+T W+D+G +K+VTSP+S ++T FAPV D+R+TLTPEL + D+ + L+ IDL +
Sbjct 775 DSMSMKTRWSDEGTEKSVTSPLSLIVTGFAPVVDIRQTLTPEL-RMDKGITDLILIDLGR 833
Query 829 GQFRLGASILTQVYKAIGTVTPDVDSFDDLKAFFALVQDWNNRSLIQAYHDIGDGGLLAT 888
GQ R+GASIL Q + +G V PDVD +DLKAFFA++Q N+ I +YHD DGGLL +
Sbjct 834 GQNRMGASILAQTHGKLGRVAPDVDDAEDLKAFFAVIQGLNSDGHILSYHDRSDGGLLVS 893
Query 889 VAEMMFASRLGVAFEQQSIES--------LFAEEIGAVVQLKAADWDAVQAEIAASGLKD 940
EM FA G+ + LF EE+GAV+Q++ V A+ +A+GL+D
Sbjct 894 TLEMAFAGHCGLNLHLDGVADNVSELSAILFNEELGAVIQVRQDATPLVLAQFSAAGLED 953
Query 941 AISVVGRVNSSDQLSVN-----GLTFERAELQRAWAEVSHQIQRLRDNVETADQEFALIS 995
++V+G+ ++D++S++ + +R LQR WAE S+QIQRLRDN E ADQEF +
Sbjct 954 CVAVIGQPINNDEVSISFHGEPVFSGQRRLLQRQWAETSYQIQRLRDNAECADQEFDALL 1013
Query 996 DQNHKGLIAQATFDLNEPVEAPFIATR-RPNMAILREQGVNGHVEMAAAFDKVGFNTIDV 1054
++++ GL + FD+NE + AP+I T RP +A+LREQGVNG VEMAAAFD+ GFN IDV
Sbjct 1014 EEDNPGLTVKLGFDVNEDIAAPYIKTGVRPQVAVLREQGVNGQVEMAAAFDRAGFNAIDV 1073
Query 1055 HMSDLLAGRVDLQDFEGLVACGGFSYGDVMGAGGGWAKSVLFNPKLRDQFESFFHRDSTF 1114
HMSD+LAGRVDL DF+G+VACGGFSYGDV+GAG GWAKS LFN + RD F+ FF R +F
Sbjct 1074 HMSDILAGRVDLNDFKGMVACGGFSYGDVLGAGEGWAKSALFNSRARDAFQGFFERADSF 1133
Query 1115 SLGICNGCQMLSQLAPLIPGADAWPRFHRNVSEVFEARSVNVRVEKSVSVLLQDMQGSIL 1174
+LG+CNGCQMLS L LIPG++ WP F RN SE FEAR V+V++S S+ LQ M GS +
Sbjct 1134 TLGVCNGCQMLSNLHELIPGSEFWPHFVRNRSEQFEARVAMVQVQESASIFLQGMAGSRM 1193
Query 1175 PIAVAHGEGRV-VTTDAHLASLNANQQVTLRYVDSLGNPTQHYPLNPNGSPEAVTGVTSK 1233
PIA+AHGEG D L + + V LR+VD+ G T+ YP NPNGSP + G+T+
Sbjct 1194 PIAIAHGEGHAEFRNDDALLEADVSGTVALRFVDNHGKVTETYPANPNGSPRGIGGMTTL 1253
Query 1234 DGRATIMMPHPERNFRAIQHSWSPENWTEDGAWLRMFRNARKFI 1277
DGR TIMMPHPER FRA+Q+SW PE+W ED AW+RMFRNAR ++
Sbjct 1254 DGRVTIMMPHPERVFRAVQNSWRPEDWNEDAAWMRMFRNARAWV 1297
>Q886W6 Phosphoribosylformylglycinamidine synthase [Pseudomonas
syringae pv. tomato (strain ATCC BAA-871 / DC3000)]
Length=1298
Score = 1484 bits (3841), Expect = 0.0
Identities = 767/1304 (59%), Positives = 949/1304 (73%), Gaps = 34/1304 (3%)
Query 1 MFIVAGAPAHSSFKKAQLLTRLSS-ISSVQSFDSQWVYLFD--QALNEQQHQSALQLLND 57
M I+ GAPA S+F+ ++LL +L +S+V +++ + D L ++ Q +LL
Sbjct 1 MLILRGAPALSAFRHSKLLEQLKQKVSAVSGLYAEFAHFADVNDVLTGEEQQVLDRLLKY 60
Query 58 GSSFELRQAATDEIQVLVTPRIGTISPWSSKATDIFKNCN-TPIHRLERGILFTLKGMSE 116
G S +++ A LV PR GTISPWSSKA+DI +NC T I R+ERGI F ++G
Sbjct 61 GPSVPVQEPAGRLF--LVLPRFGTISPWSSKASDIARNCGLTKIQRIERGIAFYVEGQFS 118
Query 117 MTNE--VKQALHDRMTETVFAEIDSANALFLETSPKPLNSIDILGEGKAALVKANNEFGF 174
+ + +LHDRMT+ V + A LF PKPL ++DILG G+AAL KAN E G
Sbjct 119 DADAQAIADSLHDRMTQLVLGDHAQAAGLFSHAEPKPLTAVDILGGGRAALEKANVELGL 178
Query 175 ALSEQEIDYLTDAFTQLGRNPNDIELMMFAQANSEHCRHKIFGSEWTIDGEVQPLSLFQM 234
AL+E EIDYL +F LGRNP+DIELMMFAQANSEHCRHKIF + W IDG+ Q SLF M
Sbjct 179 ALAEDEIDYLITSFNGLGRNPHDIELMMFAQANSEHCRHKIFNASWDIDGQSQEKSLFGM 238
Query 235 IKNTYKESPDEVLSAYKDNASVIVGYDTQRFYPKKDNDTGHYIYKYKSQAAHILMKVETH 294
IKNTY+ + VLSAYKDNASVIVG RF+P D DT Y + HILMKVETH
Sbjct 239 IKNTYEMHSEGVLSAYKDNASVIVGSVAGRFFP--DPDTRQY--GAVQEPVHILMKVETH 294
Query 295 NHPTAISPFAGAATGSGGEIRDEGATGRGGKPKAGLTGFTVSNLNIPGFEQPWEENYGKP 354
NHPTAI+PF GAATGSGGEIRDEGATGRG KPKAGLTGFTVSNL IPGF QPWE YGKP
Sbjct 295 NHPTAIAPFPGAATGSGGEIRDEGATGRGAKPKAGLTGFTVSNLQIPGFVQPWEVPYGKP 354
Query 355 SRMASPLQIMIEGPLGGAAFNNEFGRPALNGYFRTFEQNVN----GEVKGFHKPIMIAGG 410
R+ + L IMIEGPLGGAAFNNEFGRPAL GYFRTFEQ++ EV+G+HKPIM+AGG
Sbjct 355 ERIVTALDIMIEGPLGGAAFNNEFGRPALTGYFRTFEQSITTPHGDEVRGYHKPIMLAGG 414
Query 411 YGNIRPDHVEKDAIQPGDLLIVLGGPAMLIGLGGGAASSVDSGTMGESLDFASVQRENPE 470
GNIR DHV+K I G LIVLGGPAMLIGLGGGAASS+ +GT LDFASVQRENPE
Sbjct 415 MGNIREDHVQKAEITVGSKLIVLGGPAMLIGLGGGAASSMATGTSSADLDFASVQRENPE 474
Query 471 MERRCQEVIDTCWRLEDFNPIVSVHDVGAGGLSNAMPELVNDHELGAILNLRKIPSLEPG 530
MERRCQEVID CW+L D NPI +HDVGAGGLSNA PELVND + G LR +P+ EPG
Sbjct 475 MERRCQEVIDRCWQLGDRNPISFIHDVGAGGLSNAFPELVNDGDRGGRFELRNVPNDEPG 534
Query 531 MSPMEIWSNEAQERYVLAIRPESLAQFEEICARERCPFAVLGEATEARHLTVEDPLFENN 590
M+P+EIWSNE+QERYVLA+ +F+ IC RERCPFAV+GEAT LTV D F N+
Sbjct 535 MAPLEIWSNESQERYVLAVGVADYERFKAICERERCPFAVVGEATAEPQLTVTDSHFGNS 594
Query 591 AVDIPMQVMLGGTPRMQRSYESIEREGTPFDTTQIDLKDAIFRVLKNPTVASKSFLITIG 650
VD+P++V+LG PRM RS G FD + +D+++++ RVL++P VASKSFLITIG
Sbjct 595 PVDMPLEVLLGKAPRMHRSVAREAEIGDDFDPSTLDIEESVQRVLRHPAVASKSFLITIG 654
Query 651 DRSITGMVARDQMVGPWQVPVADAAVTTTSLQGYTGEAMAMGERPPVALLNPAASARLAV 710
DRSITG+VARDQMVGPWQVPVAD AVT TS TGEAMAMGER P+ALL+ AS R+A+
Sbjct 655 DRSITGLVARDQMVGPWQVPVADCAVTATSFDVNTGEAMAMGERTPLALLDAPASGRMAI 714
Query 711 AEAITNIASANIEQIGDIKLSANWMAAAGQKGEDQALFEGVKAIGMEMCPALGIAIPVGK 770
E +TNIA++ IE++ DIKLSANWM+AAG GED L++ VKA+GME+CP LGI IPVGK
Sbjct 715 GETLTNIAASRIEKLSDIKLSANWMSAAGHPGEDARLYDTVKAVGMELCPELGITIPVGK 774
Query 771 DSLSMRTTWNDDGEDKAVTSPMSGVITAFAPVSDVRKTLTPELKKFDESV--LVRIDLSK 828
DS+SM+T W+D+G +K+VTSP+S ++T FAPV D+RKTLTPEL + D+ + L+ IDL +
Sbjct 775 DSMSMKTRWSDEGTEKSVTSPLSLIVTGFAPVVDIRKTLTPEL-RMDKGITDLILIDLGR 833
Query 829 GQFRLGASILTQVYKAIGTVTPDVDSFDDLKAFFALVQDWNNRSLIQAYHDIGDGGLLAT 888
GQ R+GASIL Q + +G V PDVD +DLKAFFA++Q N+ I +YHD DGGLL +
Sbjct 834 GQNRMGASILAQTHGKLGRVAPDVDDAEDLKAFFAVIQGLNSDGHILSYHDRSDGGLLVS 893
Query 889 VAEMMFASRLGVAFEQQSIES--------LFAEEIGAVVQLKAADWDAVQAEIAASGLKD 940
EM FA G+ + LF EE+GAV+Q++ V A+ +A+GL+D
Sbjct 894 TLEMAFAGHCGLNLHLDGLADNVSELSAILFNEELGAVIQVRQDATPLVLAQFSAAGLED 953
Query 941 AISVVGRVNSSDQLSVNGL-----TFERAELQRAWAEVSHQIQRLRDNVETADQEFALIS 995
++V+G+ ++D++S++ L + +R LQR WAE S+QIQRLRDN E ADQEF +
Sbjct 954 CVAVIGQPINNDEVSISFLGEPVFSGQRRLLQRQWAETSYQIQRLRDNAECADQEFDALL 1013
Query 996 DQNHKGLIAQATFDLNEPVEAPFIATR-RPNMAILREQGVNGHVEMAAAFDKVGFNTIDV 1054
++++ GL + FD+NE + AP+I T RP +A+LREQGVNG VEMAAAFD+ GFN IDV
Sbjct 1014 EEDNPGLTVKLGFDVNEDIAAPYIKTGVRPQVAVLREQGVNGQVEMAAAFDRAGFNAIDV 1073
Query 1055 HMSDLLAGRVDLQDFEGLVACGGFSYGDVMGAGGGWAKSVLFNPKLRDQFESFFHRDSTF 1114
HMSD+LAGRVDL DF+G+VACGGFSYGDV+GAG GWAKS LFN + RD F+ FF R +F
Sbjct 1074 HMSDILAGRVDLNDFKGMVACGGFSYGDVLGAGEGWAKSALFNSRARDAFQGFFERSDSF 1133
Query 1115 SLGICNGCQMLSQLAPLIPGADAWPRFHRNVSEVFEARSVNVRVEKSVSVLLQDMQGSIL 1174
+LG+CNGCQMLS L LIPG++ WP F RN SE FEAR V+V++S S+ LQ M GS +
Sbjct 1134 TLGVCNGCQMLSNLHELIPGSEFWPHFVRNRSEQFEARVAMVQVQESASIFLQGMAGSRM 1193
Query 1175 PIAVAHGEGRV-VTTDAHLASLNANQQVTLRYVDSLGNPTQHYPLNPNGSPEAVTGVTSK 1233
PIA+AHGEG D L + + V LR+VD+ G T+ YP NPNGSP + G+T+
Sbjct 1194 PIAIAHGEGHAEFRNDDALLEADVSGTVALRFVDNHGKVTESYPANPNGSPRGIGGMTTL 1253
Query 1234 DGRATIMMPHPERNFRAIQHSWSPENWTEDGAWLRMFRNARKFI 1277
DGR TIMMPHPER FRA+Q+SW PE+W ED AW+RMFRNAR ++
Sbjct 1254 DGRVTIMMPHPERVFRAVQNSWRPEDWNEDAAWMRMFRNARAWV 1297
>Q3KHL4 Phosphoribosylformylglycinamidine synthase [Pseudomonas
fluorescens (strain Pf0-1)]
Length=1298
Score = 1480 bits (3832), Expect = 0.0
Identities = 770/1304 (59%), Positives = 949/1304 (73%), Gaps = 34/1304 (3%)
Query 1 MFIVAGAPAHSSFKKAQLLTRLSS-ISSVQSFDSQWVYLFDQA--LNEQQHQSALQLLND 57
M I+ GAPA S+F+ ++LL +LS + +V +++ + + L + Q +LL
Sbjct 1 MLILRGAPALSAFRHSKLLEQLSQKVPAVSGLYAEFAHFAEVTGVLTGDEQQVLARLLKY 60
Query 58 GSSFELRQAATDEIQVLVTPRIGTISPWSSKATDIFKNCN-TPIHRLERGILFTLKGMSE 116
G S + Q T + LV PR GTISPWSSKA+DI +NC + I RLERGI F + G
Sbjct 61 GPSVPV-QEPTGRL-FLVLPRFGTISPWSSKASDIARNCGLSKIQRLERGIAFYVAGQFS 118
Query 117 MTN--EVKQALHDRMTETVFAEIDSANALFLETSPKPLNSIDILGEGKAALVKANNEFGF 174
T ++ LHDRMT+ V A ++ A LF PKPL +IDILG G+AAL KAN E G
Sbjct 119 ETEAQQIADVLHDRMTQIVLANLEQAAGLFSHAEPKPLTAIDILGGGRAALEKANVELGL 178
Query 175 ALSEQEIDYLTDAFTQLGRNPNDIELMMFAQANSEHCRHKIFGSEWTIDGEVQPLSLFQM 234
AL+E EIDYL +AF L RNP+DIELMMFAQANSEHCRHKIF + W IDGE Q SLF M
Sbjct 179 ALAEDEIDYLVNAFNGLKRNPHDIELMMFAQANSEHCRHKIFNASWDIDGESQEKSLFGM 238
Query 235 IKNTYKESPDEVLSAYKDNASVIVGYDTQRFYPKKDNDTGHYIYKYKSQAAHILMKVETH 294
IKNTY+ + VLSAYKDNASVIVG RF+P D +T Y + HILMKVETH
Sbjct 239 IKNTYQMHSEGVLSAYKDNASVIVGNVAGRFFP--DPETRQY--GAVQEPVHILMKVETH 294
Query 295 NHPTAISPFAGAATGSGGEIRDEGATGRGGKPKAGLTGFTVSNLNIPGFEQPWEENYGKP 354
NHPTAI+PF GA+TGSGGEIRDEGATGRG KPKAGLTGFTVSNL IPGFEQPWE YGKP
Sbjct 295 NHPTAIAPFPGASTGSGGEIRDEGATGRGAKPKAGLTGFTVSNLQIPGFEQPWEVPYGKP 354
Query 355 SRMASPLQIMIEGPLGGAAFNNEFGRPALNGYFRTFEQNVN----GEVKGFHKPIMIAGG 410
R+ + L IMIEGPLGGAAFNNEFGRPAL GYFRTFEQ++ EV+G+HKPIM+AGG
Sbjct 355 ERIVNALDIMIEGPLGGAAFNNEFGRPALTGYFRTFEQSITTPHGDEVRGYHKPIMLAGG 414
Query 411 YGNIRPDHVEKDAIQPGDLLIVLGGPAMLIGLGGGAASSVDSGTMGESLDFASVQRENPE 470
GNIR +HV+K I G L+VLGGPAMLIGLGGGAASS+ +GT LDFASVQRENPE
Sbjct 415 MGNIREEHVKKGEIVVGSKLVVLGGPAMLIGLGGGAASSMATGTSSADLDFASVQRENPE 474
Query 471 MERRCQEVIDTCWRLEDFNPIVSVHDVGAGGLSNAMPELVNDHELGAILNLRKIPSLEPG 530
MERRCQEVID CW+L D NPI +HDVGAGGLSNA PELVND + G LR IP+ EPG
Sbjct 475 MERRCQEVIDRCWQLGDKNPISFIHDVGAGGLSNAFPELVNDGDRGGRFELRNIPNDEPG 534
Query 531 MSPMEIWSNEAQERYVLAIRPESLAQFEEICARERCPFAVLGEATEARHLTVEDPLFENN 590
M+P EIWSNE+QERYVLA+ P +F+ IC RERCPFAV+GEAT LTV D F NN
Sbjct 535 MAPHEIWSNESQERYVLAVGPADFERFKAICERERCPFAVVGEATAEPQLTVTDSHFGNN 594
Query 591 AVDIPMQVMLGGTPRMQRSYESIEREGTPFDTTQIDLKDAIFRVLKNPTVASKSFLITIG 650
VD+P++V+LG PRM RS G FD + +D+ ++I RVL +P VASKSFLITIG
Sbjct 595 PVDMPLEVLLGKAPRMHRSVVREAELGDDFDPSNLDIGESIERVLHHPAVASKSFLITIG 654
Query 651 DRSITGMVARDQMVGPWQVPVADAAVTTTSLQGYTGEAMAMGERPPVALLNPAASARLAV 710
DR+ITG+VARDQMVGPWQVPVAD AVT TS YTGEAMAMGER P+ALL+ AS R+A+
Sbjct 655 DRTITGLVARDQMVGPWQVPVADVAVTATSFDVYTGEAMAMGERTPLALLDAPASGRMAI 714
Query 711 AEAITNIASANIEQIGDIKLSANWMAAAGQKGEDQALFEGVKAIGMEMCPALGIAIPVGK 770
E ITNIA++ I ++ DIKLSANWM+AAG GED L++ VKA+GME+CP LGI IPVGK
Sbjct 715 GETITNIAASRINKLSDIKLSANWMSAAGHPGEDARLYDTVKAVGMELCPELGITIPVGK 774
Query 771 DSLSMRTTWNDDGEDKAVTSPMSGVITAFAPVSDVRKTLTPELKKFDESV--LVRIDLSK 828
DS+SM T WND+GEDK VTSPMS ++T FAPV+D+R+TLTPEL + D+ L+ IDL +
Sbjct 775 DSMSMATRWNDNGEDKTVTSPMSLIVTGFAPVADIRQTLTPEL-RMDKGTTDLILIDLGR 833
Query 829 GQFRLGASILTQVYKAIGTVTPDVDSFDDLKAFFALVQDWNNRSLIQAYHDIGDGGLLAT 888
GQ R+GASIL QV+ +G PDVD +DLKAFFA++Q N + AYHD DGGLL +
Sbjct 834 GQNRMGASILAQVHGKLGKQAPDVDDAEDLKAFFAVIQGLNADGHLLAYHDRSDGGLLTS 893
Query 889 VAEMMFASRLGVAFEQQSIES--------LFAEEIGAVVQLKAADWDAVQAEIAASGLKD 940
V EM FA G++ S+ LF EE+GAV+Q++ + A+ +A+GL D
Sbjct 894 VMEMAFAGHCGLSLNLDSVAESSAEIAAILFNEELGAVIQVRQDATPDILAQFSAAGLGD 953
Query 941 AISVVGRVNSSDQLSV--NGLTF---ERAELQRAWAEVSHQIQRLRDNVETADQEFALIS 995
+SV+G+ ++ Q+++ NG T +R LQR WAE S+QIQRLRDN + A+QEF +
Sbjct 954 CVSVIGQPINNGQINITFNGDTVFEGQRRLLQRQWAETSYQIQRLRDNADCAEQEFDALL 1013
Query 996 DQNHKGLIAQATFDLNEPVEAPFIATR-RPNMAILREQGVNGHVEMAAAFDKVGFNTIDV 1054
++++ GL + ++D+N+ + AP+I RP +A+LREQGVNG VEMAAAFD+ GFN IDV
Sbjct 1014 EEDNPGLSVKLSYDVNQDIAAPYIKKGIRPQVAVLREQGVNGQVEMAAAFDRAGFNAIDV 1073
Query 1055 HMSDLLAGRVDLQDFEGLVACGGFSYGDVMGAGGGWAKSVLFNPKLRDQFESFFHRDSTF 1114
HMSD+LAGRVDL +F+GLVACGGFSYGDV+GAG GWAKS LFN + RD F+ FF R+ +F
Sbjct 1074 HMSDILAGRVDLNEFKGLVACGGFSYGDVLGAGEGWAKSALFNSRARDAFQGFFERNDSF 1133
Query 1115 SLGICNGCQMLSQLAPLIPGADAWPRFHRNVSEVFEARSVNVRVEKSVSVLLQDMQGSIL 1174
+LG+CNGCQM+S L LIPG++ WP F RN SE FEAR V+V++S S+ LQ M GS +
Sbjct 1134 TLGVCNGCQMMSNLHELIPGSEFWPHFVRNRSEQFEARVAMVQVQESNSIFLQGMAGSRM 1193
Query 1175 PIAVAHGEGRV-VTTDAHLASLNANQQVTLRYVDSLGNPTQHYPLNPNGSPEAVTGVTSK 1233
PIA+AHGEG ++ L + + V +R+VD+ G T+ YP NPNGSP +TG+TS+
Sbjct 1194 PIAIAHGEGHAEFESEEALLEADLSGCVAMRFVDNHGKVTEAYPANPNGSPRGITGLTSR 1253
Query 1234 DGRATIMMPHPERNFRAIQHSWSPENWTEDGAWLRMFRNARKFI 1277
DGR TIMMPHPER FRA+Q+SW E+W ED W+RMFRNAR ++
Sbjct 1254 DGRVTIMMPHPERVFRAVQNSWRSEDWNEDAPWMRMFRNARVWV 1297
>Q8DF81 Phosphoribosylformylglycinamidine synthase [Vibrio vulnificus
(strain CMCP6)]
Length=1297
Score = 1471 bits (3807), Expect = 0.0
Identities = 759/1303 (58%), Positives = 948/1303 (73%), Gaps = 31/1303 (2%)
Query 1 MFIVAGAPAHSSFKKAQLLTRLSSIS-SVQSFDSQWVYLFD--QALNEQQHQSALQLLND 57
M I+ G+PA S F+ +LL V +++++ D L+ + + +LL
Sbjct 1 MRILRGSPALSEFRVNKLLELCREQDLPVTGIYAEFMHFADLTSELDAEALEKLEKLLTY 60
Query 58 GSSFELRQAATDEIQVLVTPRIGTISPWSSKATDIFKNCN-TPIHRLERGILFTLKGMSE 116
G + E + + +LVTPR GTISPWSSKATDI +NC + RLERG + ++ SE
Sbjct 61 GPTIEEHEP--QGLLLLVTPRPGTISPWSSKATDIAQNCGLNAVKRLERGTAYYVESSSE 118
Query 117 MTNE----VKQALHDRMTETVFAEIDSANALFLETSPKPLNSIDILGEGKAALVKANNEF 172
+++ VK +HDRM E VF ++++A ALF P P+ +DIL G+ AL +AN
Sbjct 119 LSSVQIDIVKSIIHDRMMEAVFGDLEAAAALFSVAQPAPMTQVDILSGGRLALEEANVSL 178
Query 173 GFALSEQEIDYLTDAFTQLGRNPNDIELMMFAQANSEHCRHKIFGSEWTIDGEVQPLSLF 232
G AL+E EIDYL + FT+LGRNPNDIELMMFAQANSEHCRHKIF ++WTIDG QP SLF
Sbjct 179 GLALAEDEIDYLVENFTKLGRNPNDIELMMFAQANSEHCRHKIFNADWTIDGVEQPKSLF 238
Query 233 QMIKNTYKESPDEVLSAYKDNASVIVGYDTQRFYPKKDNDTGHYIYKYKSQAAHILMKVE 292
+MIKNT++ +PD VLSAYKDNA+V+ G RF+P D +T Y Y ++ AHILMKVE
Sbjct 239 KMIKNTFETTPDHVLSAYKDNAAVMTGSKVGRFFP--DPETRQYNYHHED--AHILMKVE 294
Query 293 THNHPTAISPFAGAATGSGGEIRDEGATGRGGKPKAGLTGFTVSNLNIPGFEQPWEENYG 352
THNHPTAISP+ GA+TGSGGEIRDEGATG GGKPKAGL GFT SNL IPGFEQPWE ++G
Sbjct 295 THNHPTAISPWPGASTGSGGEIRDEGATGIGGKPKAGLVGFTTSNLRIPGFEQPWETDFG 354
Query 353 KPSRMASPLQIMIEGPLGGAAFNNEFGRPALNGYFRTFEQNVNG----EVKGFHKPIMIA 408
KP R+ + L IM+EGPLGGAAFNNEFGRP L GYFRT+E+ V EV+G+HKPIMIA
Sbjct 355 KPGRIVNALDIMLEGPLGGAAFNNEFGRPNLLGYFRTYEEKVTSHAGEEVRGYHKPIMIA 414
Query 409 GGYGNIRPDHVEKDAIQPGDLLIVLGGPAMLIGLGGGAASSVDSGTMGESLDFASVQREN 468
GG GNIR +HV+K I G LIVLGGPAM IGLGGGAASS+ SG E LDFASVQREN
Sbjct 415 GGMGNIRDEHVQKKEIPVGASLIVLGGPAMNIGLGGGAASSMASGQSAEDLDFASVQREN 474
Query 469 PEMERRCQEVIDTCWRLEDFNPIVSVHDVGAGGLSNAMPELVNDHELGAILNLRKIPSLE 528
PEMERRCQEVID CW+L D NPI +HDVGAGG+SNA+PELVND E G LR +P+ E
Sbjct 475 PEMERRCQEVIDRCWQLGDNNPIAFIHDVGAGGISNALPELVNDGERGGKFQLRDVPNDE 534
Query 529 PGMSPMEIWSNEAQERYVLAIRPESLAQFEEICARERCPFAVLGEATEARHLTVEDPLFE 588
PGMSP+EIW NE+QERYVLA+ PE++A F+ IC RER P+AV+G ATE RHLT+ED F+
Sbjct 535 PGMSPLEIWCNESQERYVLAVAPENMAAFDAICKRERAPYAVVGVATEERHLTLEDAHFD 594
Query 589 NNAVDIPMQVMLGGTPRMQRSYESIEREGTPFDTTQIDLKDAIFRVLKNPTVASKSFLIT 648
N +D+PM ++LG P+M R +++ + I+L +A+ RVL+ PTVA K+FLIT
Sbjct 595 NTPIDMPMDILLGKPPKMHREATTLKVDSPAMTRDGIELNEAVDRVLRLPTVAEKTFLIT 654
Query 649 IGDRSITGMVARDQMVGPWQVPVADAAVTTTSLQGYTGEAMAMGERPPVALLNPAASARL 708
IGDR++TG+VARDQMVGPWQVPVA+ AVT S Y GEAM+MGER PVALL+ ASARL
Sbjct 655 IGDRTVTGLVARDQMVGPWQVPVANCAVTAASYDTYHGEAMSMGERTPVALLDFGASARL 714
Query 709 AVAEAITNIASANIEQIGDIKLSANWMAAAGQKGEDQALFEGVKAIGMEMCPALGIAIPV 768
AV E++TNIA+ +I I IKLSANWM+ AG GED L+E VKA+G E+CPALG+ IPV
Sbjct 715 AVGESLTNIAATDIGDIKRIKLSANWMSPAGHPGEDAGLYEAVKAVGEELCPALGLTIPV 774
Query 769 GKDSLSMRTTWNDDGEDKAVTSPMSGVITAFAPVSDVRKTLTPELK-KFDESVLVRIDLS 827
GKDS+SM+T WN++GE+K VTSP+S +ITAFA V DVRKT+TP+L+ E+ LV +DL
Sbjct 775 GKDSMSMKTKWNENGEEKEVTSPLSLIITAFARVEDVRKTITPQLRTDKGETSLVLVDLG 834
Query 828 KGQFRLGASILTQVYKAIGTVTPDVDSFDDLKAFFALVQDWNNRSLIQAYHDIGDGGLLA 887
G+ RLGA+ L QVYK +G DVD+ + LK FF +Q + + AYHD GDGGLL
Sbjct 835 NGKNRLGATALAQVYKQLGDKPADVDNAEQLKGFFDAMQALVRQDKLLAYHDKGDGGLLV 894
Query 888 TVAEMMFASRLGV-----AFEQQSIESLFAEEIGAVVQLKAADWDAVQAEIAASGLKDAI 942
T+AEM FA GV A + +LF EE+GAVVQ+K + D+V + +AA+GL+
Sbjct 895 TLAEMAFAGHCGVNANIAALGDDVLAALFNEELGAVVQVKNDELDSVLSTLAANGLEACS 954
Query 943 SVVGRVNSSDQLSVNG-----LTFERAELQRAWAEVSHQIQRLRDNVETADQEFALISDQ 997
V+G +++SD + L R +L+ WAE +H++Q LRDN ADQEF D
Sbjct 955 HVIGAIDASDNFVIRSGDAVILERSRTDLRVIWAETTHKMQALRDNPACADQEFEAKKDN 1014
Query 998 NHKGLIAQATFDLNEPVEAPFIAT-RRPNMAILREQGVNGHVEMAAAFDKVGFNTIDVHM 1056
+ GL +FD+NE + AP+IA +P MAILREQGVN HVEMAAAFD+ GF D+HM
Sbjct 1015 SDPGLNVSLSFDVNEDIAAPYIAKGAKPKMAILREQGVNSHVEMAAAFDRAGFEATDIHM 1074
Query 1057 SDLLAGRVDLQDFEGLVACGGFSYGDVMGAGGGWAKSVLFNPKLRDQFESFFHRDSTFSL 1116
SD+L G+ L ++ GLVACGGFSYGDV+GAG GWAKSVLFN + R+QF++FF+R++TFSL
Sbjct 1075 SDILTGQAVLDEYHGLVACGGFSYGDVLGAGEGWAKSVLFNAQAREQFQAFFNRENTFSL 1134
Query 1117 GICNGCQMLSQLAPLIPGADAWPRFHRNVSEVFEARSVNVRVEKSVSVLLQDMQGSILPI 1176
G+CNGCQMLS L LIPGAD WPRF RN SE FEAR V V+KS SV M GS +PI
Sbjct 1135 GVCNGCQMLSNLKELIPGADLWPRFVRNESERFEARFSLVEVQKSDSVFFDGMAGSRMPI 1194
Query 1177 AVAHGEGRVVTTDA-HLASLNANQQVTLRYVDSLGNPTQHYPLNPNGSPEAVTGVTSKDG 1235
AV+HGEGRV DA HLA++ A+ V +R+VD+LGNPTQ YP NPNGSP A+TG+T+KDG
Sbjct 1195 AVSHGEGRVEVRDAQHLAAIEASGTVAVRFVDNLGNPTQQYPNNPNGSPNAITGLTTKDG 1254
Query 1236 RATIMMPHPERNFRAIQHSWSPENWTEDGAWLRMFRNARKFIG 1278
R TIMMPHPER FR + +SW+PE W E+GAW+RMF+NARK +G
Sbjct 1255 RVTIMMPHPERVFRTVANSWAPEGWGENGAWMRMFQNARKNLG 1297
>Q4KHS6 Phosphoribosylformylglycinamidine synthase [Pseudomonas
fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)]
Length=1298
Score = 1469 bits (3803), Expect = 0.0
Identities = 765/1304 (59%), Positives = 943/1304 (72%), Gaps = 34/1304 (3%)
Query 1 MFIVAGAPAHSSFKKAQLLTRLSS-ISSVQSFDSQWVYLFDQA--LNEQQHQSALQLLND 57
M I+ GAPA S+F+ ++LL +LS + +V +++ + + L + Q +LL
Sbjct 1 MLILRGAPALSAFRHSKLLEQLSQKVPAVSGLYAEFAHFAEVTGVLTGDEQQVLARLLKY 60
Query 58 GSSFELRQAATDEIQVLVTPRIGTISPWSSKATDIFKNCN-TPIHRLERGILFTLKG-MS 115
G S + Q T + LV PR GTISPWSSKA+DI +NC I RLERGI F + G S
Sbjct 61 GPSVPV-QEPTGRL-FLVLPRFGTISPWSSKASDIARNCGLAKIQRLERGIAFYVAGEFS 118
Query 116 EMTNE-VKQALHDRMTETVFAEIDSANALFLETSPKPLNSIDILGEGKAALVKANNEFGF 174
E + + ALHDRMT+ V A ++ A LF PKPL +IDILG G+AAL +AN+E G
Sbjct 119 EAEAQLIADALHDRMTQIVVANLEQAAGLFSHAEPKPLTAIDILGGGRAALEQANSELGL 178
Query 175 ALSEQEIDYLTDAFTQLGRNPNDIELMMFAQANSEHCRHKIFGSEWTIDGEVQPLSLFQM 234
AL+E EIDYL +AF L RNP+DIELMMFAQANSEHCRHKIF + W IDG+ Q SLF M
Sbjct 179 ALAEDEIDYLMNAFQGLKRNPHDIELMMFAQANSEHCRHKIFNASWDIDGQSQEKSLFGM 238
Query 235 IKNTYKESPDEVLSAYKDNASVIVGYDTQRFYPKKDNDTGHYIYKYKSQAAHILMKVETH 294
IKNTY+ + VLSAYKDNA+VIVG RFYP + Y + HILMKVETH
Sbjct 239 IKNTYQMHNEGVLSAYKDNAAVIVGSVAGRFYPNPETRQ----YGAVQEPVHILMKVETH 294
Query 295 NHPTAISPFAGAATGSGGEIRDEGATGRGGKPKAGLTGFTVSNLNIPGFEQPWEENYGKP 354
NHPTAI+PF GA+TGSGGEIRDEGATGRG KPKAGLTGFTVSNL IPGFEQPWE YGKP
Sbjct 295 NHPTAIAPFPGASTGSGGEIRDEGATGRGAKPKAGLTGFTVSNLQIPGFEQPWEVPYGKP 354
Query 355 SRMASPLQIMIEGPLGGAAFNNEFGRPALNGYFRTFEQNVN----GEVKGFHKPIMIAGG 410
R+ + L IMIEGPLGGAAFNNEFGRPAL GYFRTFEQ++ EV+G+HKPIM+AGG
Sbjct 355 ERIVTALDIMIEGPLGGAAFNNEFGRPALTGYFRTFEQSITTPRGDEVRGYHKPIMLAGG 414
Query 411 YGNIRPDHVEKDAIQPGDLLIVLGGPAMLIGLGGGAASSVDSGTMGESLDFASVQRENPE 470
GNIR +HV+K I G LIVLGGPAMLIGLGGGAASS+ +GT LDFASVQRENPE
Sbjct 415 MGNIRDEHVQKGEITVGSKLIVLGGPAMLIGLGGGAASSMATGTSSADLDFASVQRENPE 474
Query 471 MERRCQEVIDTCWRLEDFNPIVSVHDVGAGGLSNAMPELVNDHELGAILNLRKIPSLEPG 530
MERRCQEVID CW+L D NPI +HDVGAGGLSNA PELVND G LR IP+ EPG
Sbjct 475 MERRCQEVIDRCWQLGDNNPISFIHDVGAGGLSNAFPELVNDGGRGGRFELRNIPNDEPG 534
Query 531 MSPMEIWSNEAQERYVLAIRPESLAQFEEICARERCPFAVLGEATEARHLTVEDPLFENN 590
M+P EIWSNE+QERYVLA+ +F+ IC RERCPFAV+GEAT LTV D F N+
Sbjct 535 MAPHEIWSNESQERYVLAVGAADFERFKAICERERCPFAVVGEATAEPQLTVTDSHFGNS 594
Query 591 AVDIPMQVMLGGTPRMQRSYESIEREGTPFDTTQIDLKDAIFRVLKNPTVASKSFLITIG 650
VD+P++V+LG PRM RS G FD + +D+ ++I RVL +P VASKSFLITIG
Sbjct 595 PVDMPLEVLLGKAPRMHRSAVRENELGDDFDPSTLDIAESIERVLHHPAVASKSFLITIG 654
Query 651 DRSITGMVARDQMVGPWQVPVADAAVTTTSLQGYTGEAMAMGERPPVALLNPAASARLAV 710
DR+ITG+VARDQMVGPWQVPVAD AVT TS YTGEAMAMGER P+ALL+ AS R+A+
Sbjct 655 DRTITGLVARDQMVGPWQVPVADVAVTATSFDVYTGEAMAMGERTPLALLDAPASGRMAI 714
Query 711 AEAITNIASANIEQIGDIKLSANWMAAAGQKGEDQALFEGVKAIGMEMCPALGIAIPVGK 770
E +TNIA++ I +I DIKLSANWM+AAG GED L++ VKA+GME+CP LGI IPVGK
Sbjct 715 GETLTNIAASRINKISDIKLSANWMSAAGHPGEDARLYDTVKAVGMELCPELGITIPVGK 774
Query 771 DSLSMRTTWNDDGEDKAVTSPMSGVITAFAPVSDVRKTLTPELKKFDESV--LVRIDLSK 828
DS+SM T WN++G DK+VTSP+S ++T FAPV+D+R+TLTP+L + D+ L+ IDL +
Sbjct 775 DSMSMATRWNEEGVDKSVTSPLSLIVTGFAPVADIRQTLTPQL-RMDKGTTDLILIDLGR 833
Query 829 GQFRLGASILTQVYKAIGTVTPDVDSFDDLKAFFALVQDWNNRSLIQAYHDIGDGGLLAT 888
GQ R+GASIL Q + +G+ PDVD +DLKAFFA++Q N + AYHD DGGLL +
Sbjct 834 GQNRMGASILAQTHGKLGSQAPDVDDAEDLKAFFAVIQGLNADGHLLAYHDRSDGGLLVS 893
Query 889 VAEMMFASRLGVAFEQQSIES--------LFAEEIGAVVQLKAADWDAVQAEIAASGLKD 940
EM FA G+ ++ LF EE+GAV+Q++ V A+ +A+GL D
Sbjct 894 AVEMAFAGHCGLNLSLDAVAENTAEIAAILFNEELGAVIQVRQDATPDVLAQFSAAGLGD 953
Query 941 AISVVGRV--NSSDQLSVNG---LTFERAELQRAWAEVSHQIQRLRDNVETADQEFALIS 995
++V+G+ N +S NG T +R LQR WAE S+QIQRLRDN + A+QEF ++
Sbjct 954 CVAVIGQPINNGEVSISYNGESVFTGQRRLLQRQWAETSYQIQRLRDNADCAEQEFDVVL 1013
Query 996 DQNHKGLIAQATFDLNEPVEAPFIATR-RPNMAILREQGVNGHVEMAAAFDKVGFNTIDV 1054
++++ GL + FD+N+ + AP+I RP +A+LREQGVNG VEMAAAFD+ GFN IDV
Sbjct 1014 EEDNPGLSVKLGFDVNQDIAAPYIKKGVRPQVAVLREQGVNGQVEMAAAFDRAGFNAIDV 1073
Query 1055 HMSDLLAGRVDLQDFEGLVACGGFSYGDVMGAGGGWAKSVLFNPKLRDQFESFFHRDSTF 1114
HMSD+LAGRVDL DF+G+VACGGFSYGDV+GAG GWAKS LFN + RD F+ FF R +F
Sbjct 1074 HMSDILAGRVDLNDFKGMVACGGFSYGDVLGAGEGWAKSALFNSRARDAFQGFFERTDSF 1133
Query 1115 SLGICNGCQMLSQLAPLIPGADAWPRFHRNVSEVFEARSVNVRVEKSVSVLLQDMQGSIL 1174
+LG+CNGCQM+S L LIPG++ WP F RN SE FEAR V+V++S S+ LQ M GS +
Sbjct 1134 TLGVCNGCQMMSNLHELIPGSEFWPHFVRNRSEQFEARVAMVQVQESNSIFLQGMAGSRM 1193
Query 1175 PIAVAHGEGRV-VTTDAHLASLNANQQVTLRYVDSLGNPTQHYPLNPNGSPEAVTGVTSK 1233
PIA+AHGEG ++ L + + V LR+VD+ G T+ YP NPNGSP +TG+TS+
Sbjct 1194 PIAIAHGEGHAEFESEEALLEADLSGCVALRFVDNHGKVTERYPANPNGSPRGITGLTSR 1253
Query 1234 DGRATIMMPHPERNFRAIQHSWSPENWTEDGAWLRMFRNARKFI 1277
DGR TIMMPHPER FRA+Q+SW P+ W EDGAW+RMFRNAR ++
Sbjct 1254 DGRVTIMMPHPERVFRAVQNSWRPDEWNEDGAWMRMFRNARVWV 1297
>Q32D15 Phosphoribosylformylglycinamidine synthase [Shigella dysenteriae
serotype 1 (strain Sd197)]
Length=1295
Score = 1467 bits (3799), Expect = 0.0
Identities = 760/1301 (58%), Positives = 943/1301 (72%), Gaps = 30/1301 (2%)
Query 1 MFIVAGAPAHSSFKKAQLLTRLSSIS-SVQSFDSQWVYLFD--QALNEQQHQSALQLLND 57
M I+ G+PA S+F+ +LL R + V + +++V+ D LN+ +H +LL
Sbjct 2 MEILRGSPALSAFRINKLLARFQAARLPVHNIYAEYVHFADLNAPLNDDEHAQLERLLKY 61
Query 58 GSSFELRQAATDEIQVLVTPRIGTISPWSSKATDIFKNCNTP-IHRLERGILFTLKG--- 113
G + L A +LVTPR+GTISPWSSKATDI NC ++RLERG+ + ++
Sbjct 62 GPA--LASHAPQGKLLLVTPRLGTISPWSSKATDIAHNCGLQQVNRLERGVAYYIEAGTL 119
Query 114 MSEMTNEVKQALHDRMTETVFAEIDSANALFLETSPKPLNSIDILGEGKAALVKANNEFG 173
+E +V LHDRM ETVF +D A LF P P+ S+D+LG+G+ AL+ AN G
Sbjct 120 TNEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLG 179
Query 174 FALSEQEIDYLTDAFTQLGRNPNDIELMMFAQANSEHCRHKIFGSEWTIDGEVQPLSLFQ 233
AL+E EIDYL DAFT+LGRNPNDIEL MFAQANSEHCRHKIF ++W IDGE QP SLF+
Sbjct 180 LALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGEQQPKSLFK 239
Query 234 MIKNTYKESPDEVLSAYKDNASVIVGYDTQRFYPKKDNDTGHYIYKYKSQAAHILMKVET 293
MIKNT++ +PD VLSAYKDNA+V+ G + R++ D++TG Y + + AHILMKVET
Sbjct 240 MIKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFA--DHETGRY--DFHQEPAHILMKVET 295
Query 294 HNHPTAISPFAGAATGSGGEIRDEGATGRGGKPKAGLTGFTVSNLNIPGFEQPWEENYGK 353
HNHPTAISP+ GAATGSGGEIRDEGATGRG KPKAGL GF+VSNL IPGFEQPWEE++GK
Sbjct 296 HNHPTAISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGK 355
Query 354 PSRMASPLQIMIEGPLGGAAFNNEFGRPALNGYFRTFEQNVNG----EVKGFHKPIMIAG 409
P R+ + L IM EGPLGGAAFNNEFGRPALNGYFRT+E+ VN E++G+HKPIM+AG
Sbjct 356 PERIVTALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAG 415
Query 410 GYGNIRPDHVEKDAIQPGDLLIVLGGPAMLIGLGGGAASSVDSGTMGESLDFASVQRENP 469
G GNIR DHV+K I G L+VLGGPAM IGLGGGAASS+ SG LDFASVQR+NP
Sbjct 416 GIGNIRADHVQKGEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNP 475
Query 470 EMERRCQEVIDTCWRLEDFNPIVSVHDVGAGGLSNAMPELVNDHELGAILNLRKIPSLEP 529
EMERRCQEVID CW+L D NPI+ +HDVGAGGLSNAMPELV+D G LR I S EP
Sbjct 476 EMERRCQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEP 535
Query 530 GMSPMEIWSNEAQERYVLAIRPESLAQFEEICARERCPFAVLGEATEARHLTVEDPLFEN 589
GMSP+EIW NE+QERYVLA+ + L F+E+C RER P+AV+GEATE HL++ D F+N
Sbjct 536 GMSPLEIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDN 595
Query 590 NAVDIPMQVMLGGTPRMQRSYESIEREGTPFDTTQIDLKDAIFRVLKNPTVASKSFLITI 649
+D+P+ V+LG TP+M R ++++ +G I + DA+ RVL PTVA K+FL+TI
Sbjct 596 QPIDLPLDVLLGKTPKMTRDVQTLKAKGDALVREGITIADAVKRVLHLPTVAEKTFLVTI 655
Query 650 GDRSITGMVARDQMVGPWQVPVADAAVTTTSLQGYTGEAMAMGERPPVALLNPAASARLA 709
GDRS+TGMVARDQMVGPWQVPVA+ AVTT SL Y GEAMA+GER PVALL+ AASARLA
Sbjct 656 GDRSVTGMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLA 715
Query 710 VAEAITNIASANIEQIGDIKLSANWMAAAGQKGEDQALFEGVKAIGMEMCPALGIAIPVG 769
V EA+TNIA+ I I IKLSANWMAAAG GED L+E VKA+G E+CPALG+ IPVG
Sbjct 716 VGEALTNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVG 775
Query 770 KDSLSMRTTWNDDGEDKAVTSPMSGVITAFAPVSDVRKTLTPELKKFDESVLVRIDLSKG 829
KDS+SM+T W + E++ +TSP+S VI+AFA + DVR T+TP+L D ++L+ IDL KG
Sbjct 776 KDSMSMKTRWQEGNEEREMTSPLSLVISAFARLEDVRHTITPQLSTEDNALLL-IDLGKG 834
Query 830 QFRLGASILTQVYKAIGTVTPDVDSFDDLKAFFALVQDWNNRSLIQAYHDIGDGGLLATV 889
LGA+ L QVY+ +G DV LK F+ +Q + + AYHD DGGLL T+
Sbjct 835 NNALGATALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTL 894
Query 890 AEMMFASRLGV-----AFEQQSIESLFAEEIGAVVQLKAADWDAVQAEIAASGLKDAISV 944
AEM FA G+ + +LF EE+GAV+Q++AAD +AV++ +A GL D +
Sbjct 895 AEMAFAGHCGIDADIATLGDDRLAALFNEELGAVIQVRAADREAVESVLAQHGLADCVHY 954
Query 945 VGRVNSSDQ--LSVNGLTF---ERAELQRAWAEVSHQIQRLRDNVETADQEFALISDQNH 999
VG+ S D+ ++ NG T R L+ WAE + Q+QRLRDN E ADQE S+
Sbjct 955 VGQAVSGDRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDAD 1014
Query 1000 KGLIAQATFDLNEPVEAPFIAT-RRPNMAILREQGVNGHVEMAAAFDKVGFNTIDVHMSD 1058
GL + +FD+NE V AP+IAT RP +A+LREQGVN HVEMAAAF + GF+ IDVHMSD
Sbjct 1015 PGLNVKLSFDINEDVAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSD 1074
Query 1059 LLAGRVDLQDFEGLVACGGFSYGDVMGAGGGWAKSVLFNPKLRDQFESFFHRDSTFSLGI 1118
LLAGR L+DF LVACGGFSYGDV+GAG GWAKS+LFN ++RD+F +FFHR T +LG+
Sbjct 1075 LLAGRTGLEDFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGV 1134
Query 1119 CNGCQMLSQLAPLIPGADAWPRFHRNVSEVFEARSVNVRVEKSVSVLLQDMQGSILPIAV 1178
CNGCQM+S L LIPG++ WPRF RN S+ FEAR V V +S S+LLQ M GS +PIAV
Sbjct 1135 CNGCQMMSNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAV 1194
Query 1179 AHGEGRVVTTD-AHLASLNANQQVTLRYVDSLGNPTQHYPLNPNGSPEAVTGVTSKDGRA 1237
+HGEGRV D AHLA+L + V LRYVD+ G T+ YP NPNGSP +T VT++ GR
Sbjct 1195 SHGEGRVEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRV 1254
Query 1238 TIMMPHPERNFRAIQHSWSPENWTEDGAWLRMFRNARKFIG 1278
TIMMPHPER FR + +SW PENW EDG W+R+FRNARK +G
Sbjct 1255 TIMMPHPERVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG 1295
>P15254 Phosphoribosylformylglycinamidine synthase [Escherichia
coli (strain K12)]
Length=1295
Score = 1467 bits (3797), Expect = 0.0
Identities = 760/1301 (58%), Positives = 942/1301 (72%), Gaps = 30/1301 (2%)
Query 1 MFIVAGAPAHSSFKKAQLLTRLSSIS-SVQSFDSQWVYLFD--QALNEQQHQSALQLLND 57
M I+ G+PA S+F+ +LL R + V + +++V+ D LN+ +H +LL
Sbjct 2 MEILRGSPALSAFRINKLLARFQAARLPVHNIYAEYVHFADLNAPLNDDEHAQLERLLKY 61
Query 58 GSSFELRQAATDEIQVLVTPRIGTISPWSSKATDIFKNCNTP-IHRLERGILFTLKG--- 113
G + L A +LVTPR GTISPWSSKATDI NC ++RLERG+ + ++
Sbjct 62 GPA--LASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGVAYYIEAGTL 119
Query 114 MSEMTNEVKQALHDRMTETVFAEIDSANALFLETSPKPLNSIDILGEGKAALVKANNEFG 173
+E +V LHDRM ETVF +D A LF P P+ S+D+LG+G+ AL+ AN G
Sbjct 120 TNEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLG 179
Query 174 FALSEQEIDYLTDAFTQLGRNPNDIELMMFAQANSEHCRHKIFGSEWTIDGEVQPLSLFQ 233
AL+E EIDYL DAFT+LGRNPNDIEL MFAQANSEHCRHKIF ++W IDGE QP SLF+
Sbjct 180 LALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWVIDGEQQPKSLFK 239
Query 234 MIKNTYKESPDEVLSAYKDNASVIVGYDTQRFYPKKDNDTGHYIYKYKSQAAHILMKVET 293
MIKNT++ +PD VLSAYKDNA+V+ G + R++ D++TG Y + + AHILMKVET
Sbjct 240 MIKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFA--DHETGRY--DFHQEPAHILMKVET 295
Query 294 HNHPTAISPFAGAATGSGGEIRDEGATGRGGKPKAGLTGFTVSNLNIPGFEQPWEENYGK 353
HNHPTAISP+ GAATGSGGEIRDEGATGRG KPKAGL GF+VSNL IPGFEQPWEE++GK
Sbjct 296 HNHPTAISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGK 355
Query 354 PSRMASPLQIMIEGPLGGAAFNNEFGRPALNGYFRTFEQNVNG----EVKGFHKPIMIAG 409
P R+ + L IM EGPLGGAAFNNEFGRPALNGYFRT+E+ VN E++G+HKPIM+AG
Sbjct 356 PERIVTALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAG 415
Query 410 GYGNIRPDHVEKDAIQPGDLLIVLGGPAMLIGLGGGAASSVDSGTMGESLDFASVQRENP 469
G GNIR DHV+K I G L+VLGGPAM IGLGGGAASS+ SG LDFASVQR+NP
Sbjct 416 GIGNIRADHVQKGEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNP 475
Query 470 EMERRCQEVIDTCWRLEDFNPIVSVHDVGAGGLSNAMPELVNDHELGAILNLRKIPSLEP 529
EMERRCQEVID CW+L D NPI+ +HDVGAGGLSNAMPELV+D G LR+I S EP
Sbjct 476 EMERRCQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELREILSDEP 535
Query 530 GMSPMEIWSNEAQERYVLAIRPESLAQFEEICARERCPFAVLGEATEARHLTVEDPLFEN 589
GMSP+EIW NE+QERYVLA+ + L F+E+C RER P+AV+GEATE HL++ D F+N
Sbjct 536 GMSPLEIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDN 595
Query 590 NAVDIPMQVMLGGTPRMQRSYESIEREGTPFDTTQIDLKDAIFRVLKNPTVASKSFLITI 649
+D+P+ V+LG TP+M R ++++ +G I + DA+ RVL PTVA K+FL+TI
Sbjct 596 QPIDLPLDVLLGKTPKMTRDVQTLKAKGDALAREGITIADAVKRVLHLPTVAEKTFLVTI 655
Query 650 GDRSITGMVARDQMVGPWQVPVADAAVTTTSLQGYTGEAMAMGERPPVALLNPAASARLA 709
GDRS+TGMVARDQMVGPWQVPVA+ AVTT SL Y GEAMA+GER PVALL+ AASARLA
Sbjct 656 GDRSVTGMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLA 715
Query 710 VAEAITNIASANIEQIGDIKLSANWMAAAGQKGEDQALFEGVKAIGMEMCPALGIAIPVG 769
V EA+TNIA+ I I IKLSANWMAAAG GED L+E VKA+G E+CPALG+ IPVG
Sbjct 716 VGEALTNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVG 775
Query 770 KDSLSMRTTWNDDGEDKAVTSPMSGVITAFAPVSDVRKTLTPELKKFDESVLVRIDLSKG 829
KDS+SM+T W + E++ +TSP+S VI+AFA V DVR T+TP+L D ++L+ IDL KG
Sbjct 776 KDSMSMKTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLSTEDNALLL-IDLGKG 834
Query 830 QFRLGASILTQVYKAIGTVTPDVDSFDDLKAFFALVQDWNNRSLIQAYHDIGDGGLLATV 889
LGA+ L QVY+ +G DV LK F+ +Q + + AYHD DGGLL T+
Sbjct 835 NNALGATALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTL 894
Query 890 AEMMFASRLGV-----AFEQQSIESLFAEEIGAVVQLKAADWDAVQAEIAASGLKDAISV 944
AEM FA G+ + +LF EE+GAV+Q++AAD +AV++ +A GL D +
Sbjct 895 AEMAFAGHCGIDADIATLGDDRLAALFNEELGAVIQVRAADREAVESVLAQHGLADCVHY 954
Query 945 VGRVNSSDQ--LSVNGLTF---ERAELQRAWAEVSHQIQRLRDNVETADQEFALISDQNH 999
VG+ S D+ ++ NG T R L+ WAE + Q+QRLRDN E ADQE S+
Sbjct 955 VGQAVSGDRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDAD 1014
Query 1000 KGLIAQATFDLNEPVEAPFIAT-RRPNMAILREQGVNGHVEMAAAFDKVGFNTIDVHMSD 1058
GL + +FD+NE V AP+IAT RP +A+LREQGVN HVEMAAAF + GF+ IDVHMSD
Sbjct 1015 PGLNVKLSFDINEDVAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSD 1074
Query 1059 LLAGRVDLQDFEGLVACGGFSYGDVMGAGGGWAKSVLFNPKLRDQFESFFHRDSTFSLGI 1118
LL GR L+DF LVACGGFSYGDV+GAG GWAKS+LFN ++RD+F +FFHR T +LG+
Sbjct 1075 LLTGRTGLEDFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGV 1134
Query 1119 CNGCQMLSQLAPLIPGADAWPRFHRNVSEVFEARSVNVRVEKSVSVLLQDMQGSILPIAV 1178
CNGCQM+S L LIPG++ WPRF RN S+ FEAR V V +S S+LLQ M GS +PIAV
Sbjct 1135 CNGCQMMSNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAV 1194
Query 1179 AHGEGRVVTTD-AHLASLNANQQVTLRYVDSLGNPTQHYPLNPNGSPEAVTGVTSKDGRA 1237
+HGEGRV D AHLA+L + V LRYVD+ G T+ YP NPNGSP +T VT++ GR
Sbjct 1195 SHGEGRVEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRV 1254
Query 1238 TIMMPHPERNFRAIQHSWSPENWTEDGAWLRMFRNARKFIG 1278
TIMMPHPER FR + +SW PENW EDG W+R+FRNARK +G
Sbjct 1255 TIMMPHPERVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG 1295
>Q8XA46 Phosphoribosylformylglycinamidine synthase [Escherichia
coli O157:H7]
Length=1295
Score = 1467 bits (3797), Expect = 0.0
Identities = 761/1301 (58%), Positives = 942/1301 (72%), Gaps = 30/1301 (2%)
Query 1 MFIVAGAPAHSSFKKAQLLTRLSSIS-SVQSFDSQWVYLFD--QALNEQQHQSALQLLND 57
M I+ G+PA S+F+ +LL R + V + +++V+ D LN+ +H +LL
Sbjct 2 MEILRGSPALSAFRINKLLARFQAARLPVHNIYAEYVHFADLNAPLNDDEHAQLERLLKY 61
Query 58 GSSFELRQAATDEIQVLVTPRIGTISPWSSKATDIFKNCNTP-IHRLERGILFTLKG--- 113
G + L A +LVTPR GTISPWSSKATDI NC ++RLERG+ + ++
Sbjct 62 GPA--LASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGVAYYIEAGTL 119
Query 114 MSEMTNEVKQALHDRMTETVFAEIDSANALFLETSPKPLNSIDILGEGKAALVKANNEFG 173
+E +V LHDRM ETVF +D A LF P P+ S+D+LG+G+ AL+ AN G
Sbjct 120 TNEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLG 179
Query 174 FALSEQEIDYLTDAFTQLGRNPNDIELMMFAQANSEHCRHKIFGSEWTIDGEVQPLSLFQ 233
AL+E EIDYL DAFT+LGRNPNDIEL MFAQANSEHCRHKIF ++W IDGE QP SLF+
Sbjct 180 LALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGEQQPKSLFK 239
Query 234 MIKNTYKESPDEVLSAYKDNASVIVGYDTQRFYPKKDNDTGHYIYKYKSQAAHILMKVET 293
MIKNT++ +PD VLSAYKDNA+V+ G + R++ D++TG Y + + AHILMKVET
Sbjct 240 MIKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFA--DHETGRY--DFHQEPAHILMKVET 295
Query 294 HNHPTAISPFAGAATGSGGEIRDEGATGRGGKPKAGLTGFTVSNLNIPGFEQPWEENYGK 353
HNHPTAISP+ GAATGSGGEIRDEGATGRG KPKAGL GF+VSNL IPGFEQPWEE++GK
Sbjct 296 HNHPTAISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGK 355
Query 354 PSRMASPLQIMIEGPLGGAAFNNEFGRPALNGYFRTFEQNVNG----EVKGFHKPIMIAG 409
P R+ + L IM EGPLGGAAFNNEFGRPALNGYFRT+E+ VN E++G+HKPIM+AG
Sbjct 356 PERIVTALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAG 415
Query 410 GYGNIRPDHVEKDAIQPGDLLIVLGGPAMLIGLGGGAASSVDSGTMGESLDFASVQRENP 469
G GNIR DHV+K I G L+VLGGPAM IGLGGGAASS+ SG LDFASVQR+NP
Sbjct 416 GIGNIRADHVQKGEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNP 475
Query 470 EMERRCQEVIDTCWRLEDFNPIVSVHDVGAGGLSNAMPELVNDHELGAILNLRKIPSLEP 529
EMERRCQEVID CW+L D NPI+ +HDVGAGGLSNAMPELV+D G LR I S EP
Sbjct 476 EMERRCQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEP 535
Query 530 GMSPMEIWSNEAQERYVLAIRPESLAQFEEICARERCPFAVLGEATEARHLTVEDPLFEN 589
GMSP+EIW NE+QERYVLA+ + L F+E+C RER P+AV+GEATE HL++ D F+N
Sbjct 536 GMSPLEIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDN 595
Query 590 NAVDIPMQVMLGGTPRMQRSYESIEREGTPFDTTQIDLKDAIFRVLKNPTVASKSFLITI 649
+D+P+ V+LG TP+M R ++++ +G I + DA+ RVL PTVA K+FL+TI
Sbjct 596 QPIDLPLDVLLGKTPKMTRDVQTLKAKGDALVREGITIADAVKRVLHLPTVAEKTFLVTI 655
Query 650 GDRSITGMVARDQMVGPWQVPVADAAVTTTSLQGYTGEAMAMGERPPVALLNPAASARLA 709
GDRS+TGMVARDQMVGPWQVPVA+ AVTT SL Y GEAMA+GER PVALL+ AASARLA
Sbjct 656 GDRSVTGMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLA 715
Query 710 VAEAITNIASANIEQIGDIKLSANWMAAAGQKGEDQALFEGVKAIGMEMCPALGIAIPVG 769
V EA+TNIA+ I I IKLSANWMAAAG GED L+E VKA+G E+CPALG+ IPVG
Sbjct 716 VGEALTNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVG 775
Query 770 KDSLSMRTTWNDDGEDKAVTSPMSGVITAFAPVSDVRKTLTPELKKFDESVLVRIDLSKG 829
KDS+SM+T W + E++ +TSP+S VI+AFA V DVR T+TP+L D ++L+ IDL KG
Sbjct 776 KDSMSMKTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLSTEDNALLL-IDLGKG 834
Query 830 QFRLGASILTQVYKAIGTVTPDVDSFDDLKAFFALVQDWNNRSLIQAYHDIGDGGLLATV 889
LGA+ L QVY+ +G DV LK F+ +Q + + AYHD DGGLL T+
Sbjct 835 NNALGATALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTL 894
Query 890 AEMMFASRLGV-----AFEQQSIESLFAEEIGAVVQLKAADWDAVQAEIAASGLKDAISV 944
AEM FA G+ + +LF EE+GAV+Q++AAD +AV++ +A GL D +
Sbjct 895 AEMAFAGHCGIDADIATLGDDRLAALFNEELGAVIQVRAADREAVESVLAQHGLADCVHY 954
Query 945 VGRVNSSDQ--LSVNGLTF---ERAELQRAWAEVSHQIQRLRDNVETADQEFALISDQNH 999
VG+ S D+ ++ NG T R L+ WAE + Q+QRLRDN E ADQE S+
Sbjct 955 VGQAVSGDRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDAD 1014
Query 1000 KGLIAQATFDLNEPVEAPFIAT-RRPNMAILREQGVNGHVEMAAAFDKVGFNTIDVHMSD 1058
GL + +FD+NE V AP+IAT RP +A+LREQGVN HVEMAAAF + GF+ IDVHMSD
Sbjct 1015 PGLNVKLSFDINEDVAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSD 1074
Query 1059 LLAGRVDLQDFEGLVACGGFSYGDVMGAGGGWAKSVLFNPKLRDQFESFFHRDSTFSLGI 1118
LLAGR L+DF LVACGGFSYGDV+GAG GWAKS+LFN ++RD+F +FFHR T +LG+
Sbjct 1075 LLAGRTGLEDFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGV 1134
Query 1119 CNGCQMLSQLAPLIPGADAWPRFHRNVSEVFEARSVNVRVEKSVSVLLQDMQGSILPIAV 1178
CNGCQM+S L LIPG++ WPRF RN S+ FEAR V V +S S+LLQ M GS +PIAV
Sbjct 1135 CNGCQMMSNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAV 1194
Query 1179 AHGEGRVVTTD-AHLASLNANQQVTLRYVDSLGNPTQHYPLNPNGSPEAVTGVTSKDGRA 1237
+HGEGRV D AHLA+L + V LRYVD+ G T+ YP NPNGSP +T VT++ GR
Sbjct 1195 SHGEGRVEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRV 1254
Query 1238 TIMMPHPERNFRAIQHSWSPENWTEDGAWLRMFRNARKFIG 1278
TIMMPHPER FR + +SW PENW EDG W+R+FRNARK +G
Sbjct 1255 TIMMPHPERVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG 1295
>Q8FF26 Phosphoribosylformylglycinamidine synthase [Escherichia
coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)]
Length=1295
Score = 1467 bits (3797), Expect = 0.0
Identities = 762/1301 (59%), Positives = 942/1301 (72%), Gaps = 30/1301 (2%)
Query 1 MFIVAGAPAHSSFKKAQLLTRLSSIS-SVQSFDSQWVYLFD--QALNEQQHQSALQLLND 57
M I+ G+PA S+F+ +LL R + V + +++V+ D LN+ +H +LL
Sbjct 2 MEILRGSPALSAFRINKLLARFQAARLPVHNIYAEYVHFADLNAPLNDDEHAQLERLLKY 61
Query 58 GSSFELRQAATDEIQVLVTPRIGTISPWSSKATDIFKNCNTP-IHRLERGILFTLKG--- 113
G + L A +LVTPR GTISPWSSKATDI NC ++RLERG+ + ++
Sbjct 62 GPA--LASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGVAYYIEAGTL 119
Query 114 MSEMTNEVKQALHDRMTETVFAEIDSANALFLETSPKPLNSIDILGEGKAALVKANNEFG 173
+E +V LHDRM ETVF +D A LF P P+ S+D+LG+G+ AL+ AN G
Sbjct 120 TNEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLG 179
Query 174 FALSEQEIDYLTDAFTQLGRNPNDIELMMFAQANSEHCRHKIFGSEWTIDGEVQPLSLFQ 233
AL+E EIDYL DAFT+LGRNPNDIEL MFAQANSEHCRHKIF ++W IDGE QP SLF+
Sbjct 180 LALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGEQQPKSLFK 239
Query 234 MIKNTYKESPDEVLSAYKDNASVIVGYDTQRFYPKKDNDTGHYIYKYKSQAAHILMKVET 293
MIKNT++ +PD VLSAYKDNA+V+ G + R++ D++TG Y + + AHILMKVET
Sbjct 240 MIKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFA--DHETGRY--DFHQEPAHILMKVET 295
Query 294 HNHPTAISPFAGAATGSGGEIRDEGATGRGGKPKAGLTGFTVSNLNIPGFEQPWEENYGK 353
HNHPTAISP+ GAATGSGGEIRDEGATGRG KPKAGL GF+VSNL IPGFEQPWEE++GK
Sbjct 296 HNHPTAISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGK 355
Query 354 PSRMASPLQIMIEGPLGGAAFNNEFGRPALNGYFRTFEQNVNG----EVKGFHKPIMIAG 409
P R+ + L IM EGPLGGAAFNNEFGRPALNGYFRT+E+ VN E++G+HKPIM+AG
Sbjct 356 PERIVTALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAG 415
Query 410 GYGNIRPDHVEKDAIQPGDLLIVLGGPAMLIGLGGGAASSVDSGTMGESLDFASVQRENP 469
G GNIR DHV+K I G L+VLGGPAM IGLGGGAASS+ SG LDFASVQR+NP
Sbjct 416 GIGNIRADHVQKGEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNP 475
Query 470 EMERRCQEVIDTCWRLEDFNPIVSVHDVGAGGLSNAMPELVNDHELGAILNLRKIPSLEP 529
EMERRCQEVID CW+L D NPI+ +HDVGAGGLSNAMPELV+D G LR I S EP
Sbjct 476 EMERRCQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEP 535
Query 530 GMSPMEIWSNEAQERYVLAIRPESLAQFEEICARERCPFAVLGEATEARHLTVEDPLFEN 589
GMSP+EIW NE+QERYVLA+ + L F+E+C RER P+AV+GEATE HL++ D F+N
Sbjct 536 GMSPLEIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDN 595
Query 590 NAVDIPMQVMLGGTPRMQRSYESIEREGTPFDTTQIDLKDAIFRVLKNPTVASKSFLITI 649
+D+P+ V+LG TP+M R ++++ +G I + DA+ RVL PTVA K+FL+TI
Sbjct 596 QPIDLPLDVLLGKTPKMTRDVQTLKAKGDALAREGITIADAVKRVLHLPTVAEKTFLVTI 655
Query 650 GDRSITGMVARDQMVGPWQVPVADAAVTTTSLQGYTGEAMAMGERPPVALLNPAASARLA 709
GDRS+TGMVARDQMVGPWQVPVA+ AVTT SL Y GEAMA+GER PVALL+ AASARLA
Sbjct 656 GDRSVTGMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLA 715
Query 710 VAEAITNIASANIEQIGDIKLSANWMAAAGQKGEDQALFEGVKAIGMEMCPALGIAIPVG 769
V EA+TNIA+ I I IKLSANWMAAAG GED L+E VKA+G E+CPALG+ IPVG
Sbjct 716 VGEALTNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVG 775
Query 770 KDSLSMRTTWNDDGEDKAVTSPMSGVITAFAPVSDVRKTLTPELKKFDESVLVRIDLSKG 829
KDS+SM+T W + E++ +TSP+S VI+AFA V DVR T+TP+L D ++L+ IDL KG
Sbjct 776 KDSMSMKTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLSTEDNALLL-IDLGKG 834
Query 830 QFRLGASILTQVYKAIGTVTPDVDSFDDLKAFFALVQDWNNRSLIQAYHDIGDGGLLATV 889
LGA+ L QVY+ +G DV LK F+ +Q + + AYHD DGGLL T+
Sbjct 835 NNALGATALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTL 894
Query 890 AEMMFASRLGV-----AFEQQSIESLFAEEIGAVVQLKAADWDAVQAEIAASGLKDAISV 944
AEM FA G+ + +LF+EE+GAV+Q++AAD +AV+A +A GL D +
Sbjct 895 AEMAFAGHCGIDADIATLGDDRLAALFSEELGAVIQVRAADREAVEAVLAQHGLADCVHY 954
Query 945 VGRVNSSDQ--LSVNGLTF---ERAELQRAWAEVSHQIQRLRDNVETADQEFALISDQNH 999
VG+ S D+ ++ NG T R L+ WAE + Q+QRLRDN E ADQE S+
Sbjct 955 VGQAVSGDRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDAD 1014
Query 1000 KGLIAQATFDLNEPVEAPFIAT-RRPNMAILREQGVNGHVEMAAAFDKVGFNTIDVHMSD 1058
GL + +FD+NE V APFIAT RP +A+LREQGVN HVEMAAAF + GF+ IDVHMSD
Sbjct 1015 PGLNVKLSFDINEDVAAPFIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSD 1074
Query 1059 LLAGRVDLQDFEGLVACGGFSYGDVMGAGGGWAKSVLFNPKLRDQFESFFHRDSTFSLGI 1118
LLAGR L+ F LVACGGFSYGDV+GAG GWAKS+LFN ++RD+F +FFHR T +LG+
Sbjct 1075 LLAGRTGLEGFHVLVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGV 1134
Query 1119 CNGCQMLSQLAPLIPGADAWPRFHRNVSEVFEARSVNVRVEKSVSVLLQDMQGSILPIAV 1178
CNGCQM+S L LIPG++ WPRF RN S+ FEAR V V +S S+LLQ M GS +PIAV
Sbjct 1135 CNGCQMMSNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAV 1194
Query 1179 AHGEGRVVTTD-AHLASLNANQQVTLRYVDSLGNPTQHYPLNPNGSPEAVTGVTSKDGRA 1237
+HGEGRV D AHLA+L + V LRYVD+ G T+ YP NPNGSP +T VT++ GR
Sbjct 1195 SHGEGRVEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRV 1254
Query 1238 TIMMPHPERNFRAIQHSWSPENWTEDGAWLRMFRNARKFIG 1278
TIMMPHPER FR + +SW PENW EDG W+R+FRNARK +G
Sbjct 1255 TIMMPHPERVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG 1295
>Q0TET1 Phosphoribosylformylglycinamidine synthase [Escherichia
coli O6:K15:H31 (strain 536 / UPEC)]
Length=1295
Score = 1466 bits (3796), Expect = 0.0
Identities = 762/1301 (59%), Positives = 941/1301 (72%), Gaps = 30/1301 (2%)
Query 1 MFIVAGAPAHSSFKKAQLLTRLSSIS-SVQSFDSQWVYLFD--QALNEQQHQSALQLLND 57
M I+ G+PA S+F+ +LL R + V + +++V+ D LN+ +H +LL
Sbjct 2 MEILRGSPALSAFRINKLLARFQAARLPVHTIYAEYVHFADLNAPLNDDEHAQLERLLKY 61
Query 58 GSSFELRQAATDEIQVLVTPRIGTISPWSSKATDIFKNCNTP-IHRLERGILFTLKG--- 113
G + L A +LVTPR GTISPWSSKATDI NC ++RLERG+ + ++
Sbjct 62 GPA--LASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGVAYYIEAGTL 119
Query 114 MSEMTNEVKQALHDRMTETVFAEIDSANALFLETSPKPLNSIDILGEGKAALVKANNEFG 173
+E +V LHDRM ETVF +D A LF P P+ S+D+LG+G+ AL+ AN G
Sbjct 120 TNEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLG 179
Query 174 FALSEQEIDYLTDAFTQLGRNPNDIELMMFAQANSEHCRHKIFGSEWTIDGEVQPLSLFQ 233
AL+E EIDYL DAFT+LGRNPNDIEL MFAQANSEHCRHKIF ++W IDGE QP SLF+
Sbjct 180 LALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWVIDGEQQPKSLFK 239
Query 234 MIKNTYKESPDEVLSAYKDNASVIVGYDTQRFYPKKDNDTGHYIYKYKSQAAHILMKVET 293
MIKNT++ +PD VLSAYKDNA+V+ G + R++ D++TG Y + + AHILMKVET
Sbjct 240 MIKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFA--DHETGRY--DFHQEPAHILMKVET 295
Query 294 HNHPTAISPFAGAATGSGGEIRDEGATGRGGKPKAGLTGFTVSNLNIPGFEQPWEENYGK 353
HNHPTAISP+ GAATGSGGEIRDEGATGRG KPKAGL GF+VSNL IPGFEQPWEE++GK
Sbjct 296 HNHPTAISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGK 355
Query 354 PSRMASPLQIMIEGPLGGAAFNNEFGRPALNGYFRTFEQNVNG----EVKGFHKPIMIAG 409
P R+ + L IM EGPLGGAAFNNEFGRPALNGYFRT+E+ VN E++G+HKPIM+AG
Sbjct 356 PERIVTALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAG 415
Query 410 GYGNIRPDHVEKDAIQPGDLLIVLGGPAMLIGLGGGAASSVDSGTMGESLDFASVQRENP 469
G GNIR DHV+K I G L+VLGGPAM IGLGGGAASS+ SG LDFASVQR+NP
Sbjct 416 GIGNIRADHVQKGEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNP 475
Query 470 EMERRCQEVIDTCWRLEDFNPIVSVHDVGAGGLSNAMPELVNDHELGAILNLRKIPSLEP 529
EMERRCQEVID CW+L D NPI+ +HDVGAGGLSNAMPELV+D G LR I S EP
Sbjct 476 EMERRCQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEP 535
Query 530 GMSPMEIWSNEAQERYVLAIRPESLAQFEEICARERCPFAVLGEATEARHLTVEDPLFEN 589
GMSP+EIW NE+QERYVLA+ + L F+E+C RER P+AV+GEATE HL++ D F+N
Sbjct 536 GMSPLEIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDN 595
Query 590 NAVDIPMQVMLGGTPRMQRSYESIEREGTPFDTTQIDLKDAIFRVLKNPTVASKSFLITI 649
+D+P+ V+LG TP+M R ++++ +G I + DA+ RVL PTVA K+FL+TI
Sbjct 596 QPIDLPLDVLLGKTPKMTRDVQTLKAKGDALAREGITIADAVKRVLHLPTVAEKTFLVTI 655
Query 650 GDRSITGMVARDQMVGPWQVPVADAAVTTTSLQGYTGEAMAMGERPPVALLNPAASARLA 709
GDRS+TGMVARDQMVGPWQVPVA+ AVTT SL Y GEAMA+GER PVALL+ AASARLA
Sbjct 656 GDRSVTGMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLA 715
Query 710 VAEAITNIASANIEQIGDIKLSANWMAAAGQKGEDQALFEGVKAIGMEMCPALGIAIPVG 769
V EA+TNIA+ I I IKLSANWMAAAG GED L+E VKA+G E+CPALG+ IPVG
Sbjct 716 VGEALTNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVG 775
Query 770 KDSLSMRTTWNDDGEDKAVTSPMSGVITAFAPVSDVRKTLTPELKKFDESVLVRIDLSKG 829
KDS+SM+T W + E+ +TSP+S VI+AFA V DVR T+TP+L D ++L+ IDL KG
Sbjct 776 KDSMSMKTRWQEGNEECEMTSPLSLVISAFARVEDVRHTITPQLSTEDNALLL-IDLGKG 834
Query 830 QFRLGASILTQVYKAIGTVTPDVDSFDDLKAFFALVQDWNNRSLIQAYHDIGDGGLLATV 889
LGA+ L QVY+ +G DV LK F+ +Q + + AYHD DGGLL T+
Sbjct 835 NNALGATALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTL 894
Query 890 AEMMFASRLGV-----AFEQQSIESLFAEEIGAVVQLKAADWDAVQAEIAASGLKDAISV 944
AEM FA G+ + +LF+EE+GAV+Q++AAD +AV+A +A GL D +
Sbjct 895 AEMAFAGHCGIDADIATLGDDRLAALFSEELGAVIQVRAADREAVEAVLAQHGLADCVHY 954
Query 945 VGRVNSSDQ--LSVNGLTF---ERAELQRAWAEVSHQIQRLRDNVETADQEFALISDQNH 999
VG+ S D+ ++ NG T R L+ WAE + Q+QRLRDN E ADQE S+
Sbjct 955 VGQAVSGDRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDAD 1014
Query 1000 KGLIAQATFDLNEPVEAPFIAT-RRPNMAILREQGVNGHVEMAAAFDKVGFNTIDVHMSD 1058
GL + +FD+NE V APFIAT RP +A+LREQGVN HVEMAAAF + GF+ IDVHMSD
Sbjct 1015 PGLNVKLSFDINEDVAAPFIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSD 1074
Query 1059 LLAGRVDLQDFEGLVACGGFSYGDVMGAGGGWAKSVLFNPKLRDQFESFFHRDSTFSLGI 1118
LLAGR L+ F LVACGGFSYGDV+GAG GWAKS+LFN ++RD+F +FFHR T +LG+
Sbjct 1075 LLAGRTGLEGFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGV 1134
Query 1119 CNGCQMLSQLAPLIPGADAWPRFHRNVSEVFEARSVNVRVEKSVSVLLQDMQGSILPIAV 1178
CNGCQM+S L LIPG++ WPRF RN S+ FEAR V V +S S+LLQ M GS +PIAV
Sbjct 1135 CNGCQMMSNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAV 1194
Query 1179 AHGEGRVVTTD-AHLASLNANQQVTLRYVDSLGNPTQHYPLNPNGSPEAVTGVTSKDGRA 1237
+HGEGRV D AHLA+L + V LRYVD+ G T+ YP NPNGSP +T VT++ GR
Sbjct 1195 SHGEGRVEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRV 1254
Query 1238 TIMMPHPERNFRAIQHSWSPENWTEDGAWLRMFRNARKFIG 1278
TIMMPHPER FR + +SW PENW EDG W+R+FRNARK +G
Sbjct 1255 TIMMPHPERVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG 1295
>Q1R8H7 Phosphoribosylformylglycinamidine synthase [Escherichia
coli (strain UTI89 / UPEC)]
Length=1295
Score = 1466 bits (3794), Expect = 0.0
Identities = 762/1301 (59%), Positives = 941/1301 (72%), Gaps = 30/1301 (2%)
Query 1 MFIVAGAPAHSSFKKAQLLTRLSSISS-VQSFDSQWVYLFD--QALNEQQHQSALQLLND 57
M I+ G+PA S+F+ +LL R + V + +++V+ D LN+ +H +LL
Sbjct 2 MEILRGSPALSAFRINKLLARFQAARLLVHTIYAEYVHFADLNAPLNDDEHAQLERLLKY 61
Query 58 GSSFELRQAATDEIQVLVTPRIGTISPWSSKATDIFKNCNTP-IHRLERGILFTLKG--- 113
G + L A +LVTPR GTISPWSSKATDI NC ++RLERG+ + ++
Sbjct 62 GPA--LASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGVAYYIEAGTL 119
Query 114 MSEMTNEVKQALHDRMTETVFAEIDSANALFLETSPKPLNSIDILGEGKAALVKANNEFG 173
+E +V LHDRM ETVF +D A LF P P+ S+D+LG+G+ AL+ AN G
Sbjct 120 TNEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLG 179
Query 174 FALSEQEIDYLTDAFTQLGRNPNDIELMMFAQANSEHCRHKIFGSEWTIDGEVQPLSLFQ 233
AL+E EIDYL DAFT+LGRNPNDIEL MFAQANSEHCRHKIF ++W IDGE QP SLF+
Sbjct 180 LALAEDEIDYLQDAFTRLGRNPNDIELYMFAQANSEHCRHKIFNADWVIDGEQQPKSLFK 239
Query 234 MIKNTYKESPDEVLSAYKDNASVIVGYDTQRFYPKKDNDTGHYIYKYKSQAAHILMKVET 293
MIKNT++ +PD VLSAYKDNA+V+ G + R++ D++TG Y + + AHILMKVET
Sbjct 240 MIKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFA--DHETGRY--DFHQEPAHILMKVET 295
Query 294 HNHPTAISPFAGAATGSGGEIRDEGATGRGGKPKAGLTGFTVSNLNIPGFEQPWEENYGK 353
HNHPTAISP+ GAATGSGGEIRDEGATGRG KPKAGL GF+VSNL IPGFEQPWEE++GK
Sbjct 296 HNHPTAISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGK 355
Query 354 PSRMASPLQIMIEGPLGGAAFNNEFGRPALNGYFRTFEQNVNG----EVKGFHKPIMIAG 409
P R+ + L IM EGPLGGAAFNNEFGRPALNGYFRT+E+ VN E++G+HKPIM+AG
Sbjct 356 PERIVTALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAG 415
Query 410 GYGNIRPDHVEKDAIQPGDLLIVLGGPAMLIGLGGGAASSVDSGTMGESLDFASVQRENP 469
G GNIR DHV+K I G L+VLGGPAM IGLGGGAASS+ SG LDFASVQR+NP
Sbjct 416 GIGNIRADHVQKGEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNP 475
Query 470 EMERRCQEVIDTCWRLEDFNPIVSVHDVGAGGLSNAMPELVNDHELGAILNLRKIPSLEP 529
EMERRCQEVID CW+L D NPI+ +HDVGAGGLSNAMPELV+D G LR I S EP
Sbjct 476 EMERRCQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEP 535
Query 530 GMSPMEIWSNEAQERYVLAIRPESLAQFEEICARERCPFAVLGEATEARHLTVEDPLFEN 589
GMSP+EIW NE+QERYVLA+ + L F+E+C RER P+AV+GEATE HL++ D F+N
Sbjct 536 GMSPLEIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDN 595
Query 590 NAVDIPMQVMLGGTPRMQRSYESIEREGTPFDTTQIDLKDAIFRVLKNPTVASKSFLITI 649
+D+P+ V+LG TP+M R ++++ +G I + DA+ RVL PTVA K+FL+TI
Sbjct 596 QPIDLPLDVLLGKTPKMTRDVQTLKAKGDALAREGITIADAVKRVLHLPTVAEKTFLVTI 655
Query 650 GDRSITGMVARDQMVGPWQVPVADAAVTTTSLQGYTGEAMAMGERPPVALLNPAASARLA 709
GDRS+TGMVARDQMVGPWQVPVA+ AVTT SL Y GEAMA+GER PVALL+ AASARLA
Sbjct 656 GDRSVTGMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLA 715
Query 710 VAEAITNIASANIEQIGDIKLSANWMAAAGQKGEDQALFEGVKAIGMEMCPALGIAIPVG 769
V EA+TNIA+ I I IKLSANWMAAAG GED L+E VKA+G E+CPALG+ IPVG
Sbjct 716 VGEALTNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVG 775
Query 770 KDSLSMRTTWNDDGEDKAVTSPMSGVITAFAPVSDVRKTLTPELKKFDESVLVRIDLSKG 829
KDS+SM+T W + E++ +TSP+S VI+AFA V DVR T+TP+L D ++L+ IDL KG
Sbjct 776 KDSMSMKTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLSTEDNALLL-IDLGKG 834
Query 830 QFRLGASILTQVYKAIGTVTPDVDSFDDLKAFFALVQDWNNRSLIQAYHDIGDGGLLATV 889
LGA+ L QVY+ +G DV LK F+ +Q + + AYHD DGGLL T+
Sbjct 835 NNALGATALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTL 894
Query 890 AEMMFASRLGV-----AFEQQSIESLFAEEIGAVVQLKAADWDAVQAEIAASGLKDAISV 944
AEM FA G+ + +LF EE+GAV+Q++AAD +AV+A +A GL D +
Sbjct 895 AEMAFAGHCGIDADIATLGDDRLAALFNEELGAVIQVRAADREAVEAVLAQHGLADCVHY 954
Query 945 VGRVNSSDQ--LSVNGLTF---ERAELQRAWAEVSHQIQRLRDNVETADQEFALISDQNH 999
VG+ S D+ ++ NG T R L+ WAE + Q+QRLRDN E ADQE S+
Sbjct 955 VGQAVSGDRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDAD 1014
Query 1000 KGLIAQATFDLNEPVEAPFIAT-RRPNMAILREQGVNGHVEMAAAFDKVGFNTIDVHMSD 1058
GL + +FD+NE V APFIAT RP +A+LREQGVN HVEMAAAF + GF+ IDVHMSD
Sbjct 1015 PGLNVKLSFDINEDVAAPFIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSD 1074
Query 1059 LLAGRVDLQDFEGLVACGGFSYGDVMGAGGGWAKSVLFNPKLRDQFESFFHRDSTFSLGI 1118
LLAGR L+ F LVACGGFSYGDV+GAG GWAKS+LFN ++RD+F +FFHR T +LG+
Sbjct 1075 LLAGRTGLEGFHVLVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGV 1134
Query 1119 CNGCQMLSQLAPLIPGADAWPRFHRNVSEVFEARSVNVRVEKSVSVLLQDMQGSILPIAV 1178
CNGCQM+S L LIPG++ WPRF RN S+ FEAR V V +S S+LLQ M GS +PIAV
Sbjct 1135 CNGCQMMSNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAV 1194
Query 1179 AHGEGRVVTTD-AHLASLNANQQVTLRYVDSLGNPTQHYPLNPNGSPEAVTGVTSKDGRA 1237
+HGEGRV D AHLA+L + V LRYVD+ G T+ YP NPNGSP +T VT++ GR
Sbjct 1195 SHGEGRVEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRV 1254
Query 1238 TIMMPHPERNFRAIQHSWSPENWTEDGAWLRMFRNARKFIG 1278
TIMMPHPER FR + +SW PENW EDG W+R+FRNARK +G
Sbjct 1255 TIMMPHPERVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG 1295
>P74881 Phosphoribosylformylglycinamidine synthase [Salmonella
typhimurium (strain LT2 / SGSC1412 / ATCC 700720)]
Length=1295
Score = 1443 bits (3735), Expect = 0.0
Identities = 746/1301 (57%), Positives = 936/1301 (72%), Gaps = 30/1301 (2%)
Query 1 MFIVAGAPAHSSFKKAQLLTRLSSIS-SVQSFDSQWVYLFD--QALNEQQHQSALQLLND 57
M I+ G+PA S+F+ +LL R + + V + +++V+ D LN+ + +LL
Sbjct 2 MEILRGSPALSAFRINKLLARFQAANLQVHNIYAEYVHFADLNAPLNDSEQAQLTRLLQY 61
Query 58 GSSFELRQAATDEIQVLVTPRIGTISPWSSKATDIFKNCNTP-IHRLERGILFTLKGMS- 115
G + A + LVTPR GTISPWSSKATDI NC + RLERG+ + ++ +
Sbjct 62 GPALSSHTPAGKLL--LVTPRPGTISPWSSKATDIAHNCGLQQVDRLERGVAYYIEASTL 119
Query 116 --EMTNEVKQALHDRMTETVFAEIDSANALFLETSPKPLNSIDILGEGKAALVKANNEFG 173
E +V LHDRM ETVF+ + A LF+ P P++S+D+LGEG+ AL+ AN G
Sbjct 120 TAEQWRQVAAELHDRMMETVFSSLTDAEKLFIHHQPAPVSSVDLLGEGRQALIDANLRLG 179
Query 174 FALSEQEIDYLTDAFTQLGRNPNDIELMMFAQANSEHCRHKIFGSEWTIDGEVQPLSLFQ 233
AL+E EIDYL +AFT+LGRNPNDIEL MFAQANSEHCRHKIF ++W IDG+ QP SLF+
Sbjct 180 LALAEDEIDYLQEAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGKPQPKSLFK 239
Query 234 MIKNTYKESPDEVLSAYKDNASVIVGYDTQRFYPKKDNDTGHYIYKYKSQAAHILMKVET 293
MIKNT++ +PD VLSAYKDNA+V+ G R++ D++TG Y + + AHILMKVET
Sbjct 240 MIKNTFETTPDYVLSAYKDNAAVMEGSAVGRYFA--DHNTGRY--DFHQEPAHILMKVET 295
Query 294 HNHPTAISPFAGAATGSGGEIRDEGATGRGGKPKAGLTGFTVSNLNIPGFEQPWEENYGK 353
HNHPTAISP+ GAATGSGGEIRDEGATGRG KPKAGL GF+VSNL IPGFEQPWEE++GK
Sbjct 296 HNHPTAISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGK 355
Query 354 PSRMASPLQIMIEGPLGGAAFNNEFGRPALNGYFRTFEQNVNG----EVKGFHKPIMIAG 409
P R+ + L IM EGPLGGAAFNNEFGRPAL GYFRT+E+ VN E++G+HKPIM+AG
Sbjct 356 PERIVTALDIMTEGPLGGAAFNNEFGRPALTGYFRTYEEKVNSHNGEELRGYHKPIMLAG 415
Query 410 GYGNIRPDHVEKDAIQPGDLLIVLGGPAMLIGLGGGAASSVDSGTMGESLDFASVQRENP 469
G GNIR DHV+K I G LIVLGGPAM IGLGGGAASS+ SG LDFASVQR+NP
Sbjct 416 GIGNIRADHVQKGEIVVGAKLIVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNP 475
Query 470 EMERRCQEVIDTCWRLEDFNPIVSVHDVGAGGLSNAMPELVNDHELGAILNLRKIPSLEP 529
EMERRCQEVID CW+L D NPI+ +HDVGAGGLSNAMPELV+D G LR I S EP
Sbjct 476 EMERRCQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEP 535
Query 530 GMSPMEIWSNEAQERYVLAIRPESLAQFEEICARERCPFAVLGEATEARHLTVEDPLFEN 589
GMSP+EIW NE+QERYVLA+ + L F+E+C RER P+AV+G+ATE +HL++ D F+N
Sbjct 536 GMSPLEIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGDATEEQHLSLHDNHFDN 595
Query 590 NAVDIPMQVMLGGTPRMQRSYESIEREGTPFDTTQIDLKDAIFRVLKNPTVASKSFLITI 649
+D+P+ V+LG TP+M R ++++ +G + I + DA+ RVL PTVA K+FL+TI
Sbjct 596 QPIDLPLDVLLGKTPKMTRDVQTLKAKGDALNRADITIADAVKRVLHLPTVAEKTFLVTI 655
Query 650 GDRSITGMVARDQMVGPWQVPVADAAVTTTSLQGYTGEAMAMGERPPVALLNPAASARLA 709
GDR++TGMVARDQMVGPWQVPVAD AVTT SL Y GEAM++GER PVALL+ AASARLA
Sbjct 656 GDRTVTGMVARDQMVGPWQVPVADCAVTTASLDSYYGEAMSIGERAPVALLDFAASARLA 715
Query 710 VAEAITNIASANIEQIGDIKLSANWMAAAGQKGEDQALFEGVKAIGMEMCPALGIAIPVG 769
V EA+TNIA+ I I IKLSANWMAAAG GED L++ VKA+G E+CP LG+ IPVG
Sbjct 716 VGEALTNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYDAVKAVGEELCPQLGLTIPVG 775
Query 770 KDSLSMRTTWNDDGEDKAVTSPMSGVITAFAPVSDVRKTLTPELKKFDESVLVRIDLSKG 829
KDS+SM+T W + E + +TSP+S VI+AFA V DVR TLTP+L D ++L+ IDL KG
Sbjct 776 KDSMSMKTRWQEGNEQREMTSPLSLVISAFARVEDVRHTLTPQLSTEDNALLL-IDLGKG 834
Query 830 QFRLGASILTQVYKAIGTVTPDVDSFDDLKAFFALVQDWNNRSLIQAYHDIGDGGLLATV 889
LGA+ L QVY+ +G DV LK F+ +Q + A+HD DGGLL T+
Sbjct 835 HNALGATALAQVYRQLGDKPADVRDVAQLKGFYDAMQALVAARKLLAWHDRSDGGLLVTL 894
Query 890 AEMMFASRLGV-----AFEQQSIESLFAEEIGAVVQLKAADWDAVQAEIAASGLKDAISV 944
AEM FA GV A + +LF EE+G V+Q++A D DAV+A +A GL D +
Sbjct 895 AEMAFAGHCGVQVDIAALGDDHLAALFNEELGGVIQVRAEDRDAVEALLAQYGLADCVHY 954
Query 945 VGRVNSSDQLSVNG-----LTFERAELQRAWAEVSHQIQRLRDNVETADQEFALISDQNH 999
+G+ + D+ + + R L+ WAE + Q+QRLRDN + ADQE ++
Sbjct 955 LGQALAGDRFVITANDQTVFSESRTTLRVWWAETTWQMQRLRDNPQCADQEHEAKANDTD 1014
Query 1000 KGLIAQATFDLNEPVEAPFIAT-RRPNMAILREQGVNGHVEMAAAFDKVGFNTIDVHMSD 1058
GL + +FD+NE + AP+IAT RP +A+LREQGVN HVEMAAAF + GF+ IDVHMSD
Sbjct 1015 PGLNVKLSFDINEDIAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSD 1074
Query 1059 LLAGRVDLQDFEGLVACGGFSYGDVMGAGGGWAKSVLFNPKLRDQFESFFHRDSTFSLGI 1118
LL GR+ L +F LVACGGFSYGDV+GAG GWAKS+LFN ++RD+FE+FFHR T +LG+
Sbjct 1075 LLGGRIGLGNFHALVACGGFSYGDVLGAGEGWAKSILFNHRVRDEFETFFHRPQTLALGV 1134
Query 1119 CNGCQMLSQLAPLIPGADAWPRFHRNVSEVFEARSVNVRVEKSVSVLLQDMQGSILPIAV 1178
CNGCQM+S L LIPG++ WPRF RN S+ FEAR V V +S S+LLQ M GS +PIAV
Sbjct 1135 CNGCQMMSNLRELIPGSELWPRFVRNHSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAV 1194
Query 1179 AHGEGRV-VTTDAHLASLNANQQVTLRYVDSLGNPTQHYPLNPNGSPEAVTGVTSKDGRA 1237
+HGEGRV V DAHLA+L + V LRYVD+ G T+ YP NPNGSP +T VT+++GR
Sbjct 1195 SHGEGRVEVRDDAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTENGRV 1254
Query 1238 TIMMPHPERNFRAIQHSWSPENWTEDGAWLRMFRNARKFIG 1278
TIMMPHPER FR + +SW PENW ED W+R+FRNARK +G
Sbjct 1255 TIMMPHPERVFRTVANSWHPENWGEDSPWMRIFRNARKQLG 1295
>O14228 Phosphoribosylformylglycinamidine synthase [Schizosaccharomyces
pombe (strain 972 / ATCC 24843)]
Length=1323
Score = 1157 bits (2994), Expect = 0.0
Identities = 635/1334 (48%), Positives = 860/1334 (64%), Gaps = 67/1334 (5%)
Query 1 MFIVAGAPAHSSFKKAQLLTRLSSISSVQSFDSQWVYLFDQALNEQQHQSALQ-LLNDGS 59
M + G A S K ++L ++S V ++ + YL N + +L+ +L+D
Sbjct 1 MLVYYGGSALSVQSKKKILEL--TVSGVSDLNAVYFYLIYTKSNSSLNCESLRPILSDLQ 58
Query 60 SFELRQAATDEIQVLVTPRIGTISPWSSKATDIFKNCN-TPIHRLERGILFTLKGMSEMT 118
E + T V V PR GTISPWSSKAT+I C + R+ERGI +++ +++
Sbjct 59 ESEFKPDGTT--MVYVFPRPGTISPWSSKATNIANVCGYKDVIRIERGIAYSVVFKDDIS 116
Query 119 NEVKQA----LHDRMTETVFAEIDSANALFLETSPKPLNSIDIL----GEGKAA---LVK 167
E+ ++ L+DRMTE + ++ + +F + P PL I++ G+ +AA L
Sbjct 117 EEMLKSALNHLYDRMTEALRFKLPEEDEVFDKHEPAPLVRIELNCGQGGDKQAATERLNH 176
Query 168 ANNEFGFALSEQEIDYLTDAFTQ----LGRNPNDIELMMFAQANSEHCRHKIFGSEWTID 223
AN +FG AL+ EIDYL + +T R P D+EL MF Q NSEHCRHKIF ++WTID
Sbjct 177 ANKKFGLALAPDEIDYLVECYTSEPSLKSREPTDVELFMFGQVNSEHCRHKIFNADWTID 236
Query 224 GEVQPLSLFQMIKNTYKESPDEVLSAYKDNASVIVGYDTQRFYPKKDNDTGHYIYKYKSQ 283
GE + SLF+MI+NT+ ++P +SAY DNA+V G F P I+ K +
Sbjct 237 GEKKDYSLFKMIRNTHLKNPQYTISAYSDNAAVFEGNSGTLFAPVNG------IWSMKDE 290
Query 284 AAHILMKVETHNHPTAISPFAGAATGSGGEIRDEGATGRGGKPKAGLTGFTVSNLNIPGF 343
L KVETHNHPTA+SPF GAATGSGGEIRDEGA G+G KAGL G++VS+LNIPG+
Sbjct 291 PVEFLGKVETHNHPTAVSPFPGAATGSGGEIRDEGAVGQGSLSKAGLAGYSVSDLNIPGY 350
Query 344 EQPWEENYGKPSRMASPLQIMIEGPLGGAAFNNEFGRPALNGYFRTFEQNV-----NGEV 398
+QPWE + GKP +A+ L IM+E P+G +AFNNEFGRP +NGYFRTF V E+
Sbjct 351 KQPWELDVGKPYHIATSLDIMLEAPIGSSAFNNEFGRPCINGYFRTFCMEVPRGDGTLEI 410
Query 399 KGFHKPIMIAGGYGNIRPDHVEKDAIQPGDLLIVLGGPAMLIGLGGGAASSVDSGTMGES 458
+G+HKPIM AGG G IR H K +I PG +IVLGGPA+L+GLGGGAASS+++G E
Sbjct 411 RGYHKPIMAAGGIGRIRKQHAFKKSIAPGSPIIVLGGPALLVGLGGGAASSMNAGEGSEE 470
Query 459 LDFASVQRENPEMERRCQEVIDTCWRLEDFNPIVSVHDVGAGGLSNAMPELVNDHELGAI 518
LDFASVQR NPEM+RR Q VID C +++ N I S+HDVGAGG+SNA+PELV+D LGA
Sbjct 471 LDFASVQRGNPEMQRRAQMVIDACTTMDE-NIIQSIHDVGAGGVSNALPELVHDAGLGAR 529
Query 519 LNLRKIPSLEPGMSPMEIWSNEAQERYVLAIRPESLAQFEEICARERCPFAVLGEATEAR 578
LR IP +EP MSPM+IW E+QERYVL+++ E L F+ IC RERCP+ V+G +T +
Sbjct 530 FELRDIPCIEPSMSPMQIWCCESQERYVLSVKSEDLDTFKSICERERCPYGVVGYSTVEQ 589
Query 579 HLTVEDPLFENNAVDIPMQVMLGGTPRMQRSYESIEREGTPFDT--------TQIDLKDA 630
L + D L+ +D+PM+V+ G P+M R E+ + FD+ + + DA
Sbjct 590 RLILTDRLYNTTPIDLPMEVLFGKPPKMSRVAETQTIPLSKFDSSLKSYLAPSSDPILDA 649
Query 631 IFRVLKNPTVASKSFLITIGDRSITGMVARDQMVGPWQVPVADAAVTTTSL-QGY-TGEA 688
+ RVL+ P VASKSFLITIGDRS+TG++ARDQMVGPWQVPVAD VT TS +G TGEA
Sbjct 650 VERVLRMPAVASKSFLITIGDRSVTGLIARDQMVGPWQVPVADVGVTVTSYGKGINTGEA 709
Query 689 MAMGERPPVALLNPAASARLAVAEAITNIASANIEQIGDIKLSANWMAAAGQKGEDQALF 748
+AMGE+P AL++ AASAR+AVAE I N+ +A+I + I+LSANWMAA GE L+
Sbjct 710 LAMGEKPISALVSAAASARMAVAECIMNLVAASIPALDRIRLSANWMAAPSHPGEGAKLY 769
Query 749 EGVKAIGMEMCPALGIAIPVGKDSLSMRTTWNDDGEDKAVTSPMSGVITAFAPVSDVRKT 808
E V+AIG+E+CP+LGI+IPVGKDS+SM WN+DG +K+VT+P+S +IT F+PV D+
Sbjct 770 EAVQAIGLELCPSLGISIPVGKDSMSMSMKWNEDGREKSVTAPLSLIITGFSPVDDLYSI 829
Query 809 LTPELKKFDE---SVLVRIDLSKGQFRLGASILTQVYKAIGTVTPDVDSFDDLKAFFALV 865
TP+L+K ++ + L+ IDL+ G+ RLG SIL Q YK +G PD+D+ D K F ++
Sbjct 830 WTPQLRKVEDIGSTSLIFIDLANGKQRLGGSILAQSYKQLGDEVPDLDNLDTFKNFINVI 889
Query 866 QDWNNRSLIQAYHDIGDGGLLATVAEMMFASRLGVAFEQQSIES-----LFAEEIGAVVQ 920
+ + IQAYHD DGGL T++EM FA +G+ E S+ S LF EE+GAV+Q
Sbjct 890 TQLHKTNYIQAYHDKSDGGLFVTLSEMAFAGHVGIECELDSLSSDNIAALFNEELGAVIQ 949
Query 921 LKAADWDAVQAEIAASGLKDAISVVGRVNSSDQLSVN-----GLTFE--RAELQRAWAEV 973
+ D V AA+GL + +G+V S +++ + F+ R++L W E
Sbjct 950 VCDRDIAKVLELFAANGLSTCVHRIGKVLSGQAQTISFSRSGKIIFKSTRSKLHGIWHET 1009
Query 974 SHQIQRLRDNVETADQEFALISDQNHKGLIAQATFDLNEPVEAPFIATRRPNMAILREQG 1033
S+++Q +RDN E A QE I+D N GL TFD N V A T RP +AILREQG
Sbjct 1010 SYKMQEIRDNPECARQEMENIADNNDPGLGYHLTFDPNVSVTADLALTSRPKVAILREQG 1069
Query 1034 VNGHVEMAAAFDKVGFNTIDVHMSDLLAGRVDLQDFEGLVACGGFSYGDVMGAGGGWAKS 1093
VNG++EMA AF GF +DVHM+D+L+GRV L DF G+ ACGGFSYGDV+G+G GWA S
Sbjct 1070 VNGYLEMAYAFYASGFTAVDVHMTDILSGRVHLDDFVGIAACGGFSYGDVLGSGNGWATS 1129
Query 1094 VLFNPKLRDQFESFFH-RDSTFSLGICNGCQMLSQLAPLIPGADAWPRFHRNVSEVFEAR 1152
+L + R++F FF+ R TF LGICNGCQ+ S+L LIPGA +WP F N S +E R
Sbjct 1130 ILLHEDARNEFYRFFNERKDTFGLGICNGCQLFSRLKSLIPGAKSWPMFTFNESAQYEGR 1189
Query 1153 SVNVRVEK---SVSVLLQDMQGSILPIAVAHGEGRVV-TTDAHLASLNANQQVTLRYVDS 1208
+V +++++ S S+ + M GS LP+ VAHGEGR V +++ + YV++
Sbjct 1190 AVMLKIDETSGSKSIFTESMAGSSLPVVVAHGEGRAVFDSESDYEQFKKEGLDLIYYVNN 1249
Query 1209 LGNPTQHYPLNPNGSPEAVTGVTSKDGRATIMMPHPERNFRAIQHSWSPEN----WTEDG 1264
T YP NPNGS +A+ GV S GR MMPHPER + +S+ P + W G
Sbjct 1250 YNERTSRYPFNPNGSRDAIAGVRSPCGRFLAMMPHPERVVLKVANSYYPHSKASEWGVHG 1309
Query 1265 AWLRMFRNARKFIG 1278
W+R+F++ARK++G
Sbjct 1310 PWIRLFQSARKWVG 1323
>Q9M8D3 Probable phosphoribosylformylglycinamidine synthase, chloroplastic/mitochondrial
[Arabidopsis thaliana]
Length=1407
Score = 773 bits (1995), Expect = 0.0
Identities = 479/1263 (38%), Positives = 705/1263 (56%), Gaps = 71/1263 (6%)
Query 64 RQAATDEIQVLVTPRIGTISPWSSKATDIFKNCN----TPIHRLERGILFTLKGMSEMTN 119
+Q + V V PR+ + WS+ A I + C T + R R +LF+ + + E N
Sbjct 164 KQEGLHAVIVEVGPRLSFTTAWSTNAVSICRACGLDEVTRLERSRRYLLFSKEPLLE--N 221
Query 120 EVKQ---ALHDRMTETVFAEIDSANALFLETS--PKPLNSIDILGEGKAALVKANNEFGF 174
++K+ +HDRMTE V+ + + ET+ P+ + + ++ +G+ AL + N E G
Sbjct 222 QIKEFAAMVHDRMTECVYTQ----KLVSFETNVVPEEVKYVPVMEKGRKALEEINQEMGL 277
Query 175 ALSEQEIDYLTDAFTQ-LGRNPNDIELMMFAQANSEHCRHKIFGSEWTIDGEVQPLSLFQ 233
A EQ++ Y T F + + R+P ++EL AQ+NSEH RH F IDG+ SL Q
Sbjct 278 AFDEQDLQYYTRLFREDIKRDPTNVELFDIAQSNSEHSRHWFFAGNMVIDGKPMDKSLMQ 337
Query 234 MIKNTYKESPDEVLSAYKDNASVIVGYDTQRFYPKKDNDTGHYIYKYKSQAAHILMKVET 293
++K+T++ + + + +KDN+S I G+ + P + ++ IL ET
Sbjct 338 IVKSTWEANRNNSVIGFKDNSSAIRGFLVNQLRPLLPGSV--CLLDVSARDLDILFTAET 395
Query 294 HNHPTAISPFAGAATGSGGEIRDEGATGRGGKPKAGLTGFTVSNLNIPGFEQPWEEN-YG 352
HN P A++P+ GA TG+GG IRD ATGRG A +G+ V NLN+ G PWE++ +
Sbjct 396 HNFPCAVAPYPGAETGAGGRIRDTHATGRGSFVVASTSGYCVGNLNMEGSYAPWEDSSFQ 455
Query 353 KPSRMASPLQIMIEGPLGGAAFNNEFGRPALNGYFRTFEQNV-NGEVKGFHKPIMIAGGY 411
PS +ASPLQI+I+ G + + N+FG P + GY RTF + +G+ + + KPIM + G
Sbjct 456 YPSNLASPLQILIDASNGASDYGNKFGEPMIQGYTRTFGMRLPSGDRREWLKPIMFSAGI 515
Query 412 GNIRPDHVEKDAIQPGDLLIVLGGPAMLIGLGGGAASSVDSGTMGESLDFASVQRENPEM 471
G I H+ K + G L++ +GGPA IG+GGGAASS+ SG LDF +VQR + EM
Sbjct 516 GQIDHTHITKGEPEVGMLVVKIGGPAYRIGMGGGAASSMVSGQNDAELDFNAVQRGDAEM 575
Query 472 ERRCQEVIDTCWRLEDFNPIVSVHDVGAGGLSNAMPELVNDHELGAILNLRKIPSLEPGM 531
++ V+ C + + NPI+S+HD GAGG N + E++ + GA +++R + + M
Sbjct 576 SQKLYRVVRACIEMGEKNPIISIHDQGAGGNCNVVKEII--YPQGAEIDIRAVVVGDHTM 633
Query 532 SPMEIWSNEAQERYVLAIRPESLAQFEEICARERCPFAVLG-----------EATEARHL 580
S +EIW E QE+ + ++ ES + IC RER AV+G ++T A
Sbjct 634 SVLEIWGAEYQEQDAILVKAESREILQSICKRERLSMAVIGTINGGGRCTLIDSTAAAKC 693
Query 581 TVEDPLFENNAVDIPMQVMLGGTPRMQRSYESIEREGTPFDTTQ-IDLKDAIFRVLKNPT 639
+ E AVD+ ++ +LG P+ + I P D I L DA+ RVL+ P+
Sbjct 694 SKEGLPPPPPAVDLELEKVLGDMPKKTFKFNRIAYAREPLDIAPGITLMDALKRVLRLPS 753
Query 640 VASKSFLITIGDRSITGMVARDQMVGPWQVPVADAAVTTTSLQGYTGEAMAMGERPPVAL 699
V+SK FL T DR +TG+VA+ Q VGP Q+ +AD AV + TG A A+GE+P L
Sbjct 754 VSSKRFLTTKVDRCVTGLVAQQQTVGPLQITLADVAVIAQTFTDLTGGACAIGEQPIKGL 813
Query 700 LNPAASARLAVAEAITNIASANIEQIGDIKLSANWMAAAGQKGEDQALFEGVKAIGMEMC 759
L+P A ARLAV EA+TN+ A + + D+K S NWM AA +GE A+++ A+ M
Sbjct 814 LDPKAMARLAVGEALTNLVWAKVTALSDVKASGNWMYAAKLEGEGSAMYDAAIALSEAMI 873
Query 760 PALGIAIPVGKDSLSMRTTWNDDGEDKAVTSPMSGVITAFAPVSDVRKTLTPELK-KFDE 818
LGIAI GKDSLSM + DGE V +P + VI+A+ D+ KT+TP+LK D+
Sbjct 874 -ELGIAIDGGKDSLSMAA--HADGE--VVKAPGNLVISAYVTCPDITKTVTPDLKLGGDD 928
Query 819 SVLVRIDLSKGQFRLGASILTQVYKAIGTVTPDVDSFDDLKAFFALVQDWNNRSLIQAYH 878
+L+ +DL+KG+ RLG S L QV+ IG PD+D LK F VQ +L+ A H
Sbjct 929 GILLHVDLAKGKRRLGGSALAQVFGQIGNDCPDLDDVPYLKNVFDGVQALIAENLVSAGH 988
Query 879 DIGDGGLLATVAEMMFASRLGVAFEQQS-----IESLFAEEIGAVVQLKAADWDAVQAEI 933
DI DGGL+ T EM FA G+ + S E+LF+EE+G V+++ + DAV ++
Sbjct 989 DISDGGLVVTALEMAFAGNKGINLDLASNGISLFETLFSEELGLVLEISKTNLDAVMEKL 1048
Query 934 AASGLKDAISVVGRVNSSD--QLSVNGLTF---ERAELQRAWAEVSHQ---IQRLRDNVE 985
A + ++G V S ++ V+G+T + + L+ W + S Q +QRL VE
Sbjct 1049 RAFDV--TAEIIGNVTDSPLIEVKVDGITHLSEKTSFLRDMWEDTSFQLEKLQRLASCVE 1106
Query 986 TADQEFALISDQNHKGLIAQATFDLNEPVEAPFIATRRPNMAILREQGVNGHVEMAAAFD 1045
+ + N K ++ + N + +P +A++RE+G NG EM+AAF
Sbjct 1107 MEKEGLKFRHEPNWKLSFIPSSTNNNYMSQ-----DVKPKVAVIREEGSNGDREMSAAFY 1161
Query 1046 KVGFNTIDVHMSDLLAGRVDLQDFEGLVACGGFSYGDVMGAGGGWAKSVLFNPKLRDQFE 1105
GF DV +SDLLAG + L F G+V GGFSY DV+ + GWA S+ FN + QF+
Sbjct 1162 AAGFEPWDVTVSDLLAGDITLDQFRGIVFVGGFSYADVLDSAKGWAASIRFNEPVLSQFQ 1221
Query 1106 SFFHRDSTFSLGICNGCQMLSQL----APLIPGA--DAWPRFHRNVSEVFEARSVNVRVE 1159
F+ R TFSLGICNGCQ+++ L P + G+ + PRF N S FE R +V ++
Sbjct 1222 EFYKRPDTFSLGICNGCQLMALLGWVPGPQVGGSLDTSQPRFVHNESGRFECRFTSVTIK 1281
Query 1160 KSVSVLLQDMQGSILPIAVAHGEGRVVTTD-AHLASLNANQQVTLRYVDSLGNPTQHYPL 1218
S S++L+ M+GS L + AHGEGR D L + + LRY D GN T+ YP
Sbjct 1282 DSPSIMLKGMEGSTLGVWAAHGEGRAYFPDEGVLDHMLHSDLAPLRYCDDDGNVTEAYPF 1341
Query 1219 NPNGSPEAVTGVTSKDGRATIMMPHPERNFRAIQHSWSPENWTEDGA----WLRMFRNAR 1274
N NGSP + + S DGR MMPHPER F Q W P +W + A WL+MF+NAR
Sbjct 1342 NLNGSPLGIAAICSPDGRHLAMMPHPERCFLMWQFPWYPTSWDVEKAGPSPWLKMFQNAR 1401
Query 1275 KFI 1277
++
Sbjct 1402 DWL 1404
>O15067 Phosphoribosylformylglycinamidine synthase [Homo sapiens]
Length=1338
Score = 720 bits (1858), Expect = 0.0
Identities = 475/1334 (36%), Positives = 694/1334 (52%), Gaps = 83/1334 (6%)
Query 7 APAHSSFKKAQLLTRLSSISSVQSFDSQWVYLFDQALNEQQHQSALQ-------LLNDGS 59
AP H+ K L L + + ++ W +AL + L LL+D +
Sbjct 18 APGHTRRKLQGKLPELQGVETELCYNVNWTA---EALPSAEETKKLMWLFGCPLLLDDVA 74
Query 60 SFELRQAATDEIQVLVTPRIGTISPWSSKATDIFKNCNT-PIHRLERGILFTLKGMSEMT 118
++++ + V PR+ +P S+ + + P+ R+E + L +
Sbjct 75 RESWLLPGSNDLLLEVGPRLNFSTPTSTNIVSVCRATGLGPVDRVETTRRYRLSFAHPPS 134
Query 119 NEVKQ----ALHDRMTETVFAEIDSANALFLETSPKPLNS-IDILGEGKAALVKANNEFG 173
EV+ LHDRMTE F + E+ P+PLN I+ILGEG+ AL KAN E G
Sbjct 135 AEVEAIALATLHDRMTEQHFPH--PIQSFSPESMPEPLNGPINILGEGRLALEKANQELG 192
Query 174 FALSEQEIDYLTDAFTQLGRNPNDIELMMFAQANSEHCRHKIFGSEWTIDGEVQPLSLFQ 233
AL ++D+ T F +L RNP+ +E AQ+NSEH RH F + +DG+ SLF+
Sbjct 193 LALDSWDLDFYTKRFQELQRNPSTVEAFDLAQSNSEHSRHWFFKGQLHVDGQKLVHSLFE 252
Query 234 MIKNTYKESPDEVLSAYKDNASVIVGYDTQRFYPKKDNDTGHYIYKYKSQAAHILMKVET 293
I +T + S + + DN+S I G + + P ++ T ++ + H++ ET
Sbjct 253 SIMSTQESSNPNNVLKFCDNSSAIQGKEVRFLRP--EDPTRPSRFQQQQGLRHVVFTAET 310
Query 294 HNHPTAISPFAGAATGSGGEIRDEGATGRGGKPKAGLTGFTVSNLNIPGFEQPWEE-NYG 352
HN PT + PF+GA TG+GG IRD TGRG AG G+ NL+IPG+ PWE+ ++
Sbjct 311 HNFPTGVCPFSGATTGTGGRIRDVQCTGRGAHVVAGTAGYCFGNLHIPGYNLPWEDPSFQ 370
Query 353 KPSRMASPLQIMIEGPLGGAAFNNEFGRPALNGYFRTFE-QNVNGEVKGFHKPIMIAGGY 411
P A PL++ IE G + + N+FG P L G+ R+ Q +G+ + + KPIM +GG
Sbjct 371 YPGNFARPLEVAIEASNGASDYGNKFGEPVLAGFARSLGLQLPDGQRREWIKPIMFSGGI 430
Query 412 GNIRPDHVEKDAIQPGDLLIVLGGPAMLIGLGGGAASSVD-SGTMGESLDFASVQRENPE 470
G++ DH+ K+A +PG ++ +GGP IG+GGGAASSV G LDF +VQR +PE
Sbjct 431 GSMEADHISKEAPEPGMEVVKVGGPVYRIGVGGGAASSVQVQGDNTSDLDFGAVQRGDPE 490
Query 471 MERRCQEVIDTCWRLEDFNPIVSVHDVGAGGLSNAMPELVNDHELGAILNLRKIPSLEPG 530
ME++ VI C NPI S+HD GAGG N + EL + GAI+ + +P
Sbjct 491 MEQKMNRVIRACVEAPKGNPICSLHDQGAGGNGNVLKELSDP--AGAIIYTSRFQLGDPT 548
Query 531 MSPMEIWSNEAQERYVLAIRPESLAQFEEICARERCPFAVLGEATEARHLTVED----PL 586
++ +EIW E QE L +R + + ARERCP +G T R + + D P+
Sbjct 549 LNALEIWGAEYQESNALLLRSPNRDFLTHVSARERCPACFVGTITGDRRIVLVDDRECPV 608
Query 587 FENNA-----------VDIPMQVMLGGTPR----MQRSYESIEREGTPFDTTQIDLKDAI 631
N VD+ ++ +LG PR +QR ++ P + + A+
Sbjct 609 RRNGQGDAPPTPLPTPVDLELEWVLGKMPRKEFFLQRKPPMLQPLALP---PGLSVHQAL 665
Query 632 FRVLKNPTVASKSFLITIGDRSITGMVARDQMVGPWQVPVADAAVTTTSLQGYTGEAMAM 691
RVL+ P VASK +L DRS+ G+VA+ Q VGP Q P+AD AV S + G A A+
Sbjct 666 ERVLRLPAVASKRYLTNKVDRSVGGLVAQQQCVGPLQTPLADVAVVALSHEELIGAATAL 725
Query 692 GERPPVALLNPAASARLAVAEAITNIASANIEQIGDIKLSANWMAAAGQKGEDQALFEGV 751
GE+P +LL+P +ARLAVAEA+TN+ A + + D+K S NWM AA GE AL +
Sbjct 726 GEQPVKSLLDPKVAARLAVAEALTNLVFALVTDLRDVKCSGNWMWAAKLPGEGAALADAC 785
Query 752 KAIGMEMCPALGIAIPVGKDSLSMRTTWNDDGEDKAVTSPMSGVITAFAPVSDVRKTLTP 811
+A+ + + ALG+A+ GKDSLSM + V +P S VI+A+A D+ T+TP
Sbjct 786 EAM-VAVMAALGVAVDGGKDSLSMAARVGTE----TVRAPGSLVISAYAVCPDITATVTP 840
Query 812 ELKKFD-ESVLVRIDLSKGQFRLGASILTQVYKAIGTVTPDVDSFDDLKAFFALVQDWNN 870
+LK + L+ + LS GQ RLG + L Q + +G PD+D ++L F++ Q
Sbjct 841 DLKHPEGRGHLLYVALSPGQHRLGGTALAQCFSQLGEHPPDLDLPENLVRAFSITQGLLK 900
Query 871 RSLIQAYHDIGDGGLLATVAEMMFASRLGVAFE-----QQSIESLFAEEIGAVVQLKAAD 925
L+ + HD+ DGGL+ + EM FA G+ + + LFAEE G V++++ D
Sbjct 901 DRLLCSGHDVSDGGLVTCLLEMAFAGNCGLQVDVPVPRVDVLSVLFAEEPGLVLEVQEPD 960
Query 926 WDAVQAEIAASGLKD-AISVVGRV--NSSDQLSVNG---LTFERAELQRAWAEVSHQIQR 979
V +GL + G ++ ++SVNG L EL+ W E S Q+ R
Sbjct 961 LAQVLKRYRDAGLHCLELGHTGEAGPHAMVRVSVNGAVVLEEPVGELRALWEETSFQLDR 1020
Query 980 LRDNVETADQEFALISDQNHKGLIAQATFDLNEPVEAPFIATRRPNMAILREQGVNGHVE 1039
L+ +E + ++ TF P P +AILRE+G NG E
Sbjct 1021 LQAEPRCVAEEERGLRERMGPSYCLPPTFPKASVPREP--GGPSPRVAILREEGSNGDRE 1078
Query 1040 MAAAFDKVGFNTIDVHMSDLLAGRVDLQDFEGLVACGGFSYGDVMGAGGGWAKSVLFNPK 1099
MA AF GF DV M DL +G + L F G+ GGFSY DV+G+ GWA +V F+P+
Sbjct 1079 MADAFHLAGFEVWDVTMQDLCSGAIGLDTFRGVAFVGGFSYADVLGSAKGWAAAVTFHPR 1138
Query 1100 LRDQFESFFHRDSTFSLGICNGCQMLSQLA---------PLIPGADAWPR-----FHRNV 1145
+ F R TFSLG+CNGCQ+L+ L G D+ P N+
Sbjct 1139 AGAELRRFRKRPDTFSLGVCNGCQLLALLGWVGGDPNEDAAEMGPDSQPARPGLLLRHNL 1198
Query 1146 SEVFEARSVNVRVEKSVSVLLQDMQGSILPIAVAHGEGRVVTTDAHL-ASLNANQQVTLR 1204
S +E+R +VRV +++L+ M+G++LP+ AHGEG V + L A + A L
Sbjct 1199 SGRYESRWASVRVGPGPALMLRGMEGAVLPVWSAHGEGYVAFSSPELQAQIEARGLAPLH 1258
Query 1205 YVDSLGNPTQHYPLNPNGSPEAVTGVTSKDGRATIMMPHPERNFRAIQHSWSPE--NWTE 1262
+ D GNPT+ YPLNPNGSP V G+ S DGR +MPHPER R Q +W P +
Sbjct 1259 WADDDGNPTEQYPLNPNGSPGGVAGICSCDGRHLAVMPHPERAVRPWQWAWRPPPFDTLT 1318
Query 1263 DGAWLRMFRNARKF 1276
WL++F NAR +
Sbjct 1319 TSPWLQLFINARNW 1332
>P35421 Phosphoribosylformylglycinamidine synthase [Drosophila
melanogaster]
Length=1354
Score = 701 bits (1810), Expect = 0.0
Identities = 473/1351 (35%), Positives = 701/1351 (52%), Gaps = 102/1351 (8%)
Query 9 AHSSFKKAQLLTRL-SSISSVQSFDSQWVYLFDQALNEQQHQSAL---------QLLNDG 58
AHS+ ++ +L RL +V S + Y + + + +H AL Q L+ G
Sbjct 11 AHSAAEEESVLRRLREEDGAVVSVRMERCYHLEYSA-QAEHSLALDELLVWLVKQPLSKG 69
Query 59 SSFE----LRQAATDEIQVLVTPRIGTISPWSSKATDIFKNCN-TPIHRLERGILFTLK- 112
S L+ + ++ + + PR +P+S+ +IF+N + + R+E + +
Sbjct 70 QSLSRQPALQSTGSSQLLLEIGPRFNFSTPYSTNCVNIFQNLGYSEVRRMETSTRYLVTF 129
Query 113 GMSEMTNEVKQ---ALHDRMTETVFAEIDSANALFLETSPKPLNS---IDILGEGKAALV 166
G E + L DRMT+ ++ E ++ A F E P+ + + +L EG+AAL
Sbjct 130 GEGSKAPEAARFVPLLGDRMTQCLYTEENTPKASFDEQLPERQANWHFVPVLEEGRAALE 189
Query 167 KANNEFGFALSEQEIDYLTDAFT-QLGRNPNDIELMMFAQANSEHCRHKIFGSEWTIDGE 225
+ N E G A ++ ++DY D F +LGRNP +EL AQ+NSEH RH F IDG
Sbjct 190 RINQELGLAFNDYDLDYYHDLFAKELGRNPTTVELFDCAQSNSEHSRHWFFRGRMVIDGV 249
Query 226 VQPLSLFQMIKNTYKESPDEVLSAYKDNASVIVGYDTQRFYPKKDNDTGHYIYKYKSQAA 285
QP SL +MI +T + + DN+S +VG+D Q P G + +S +
Sbjct 250 EQPKSLIRMIMDTQAHTNPNNTIKFSDNSSAMVGFDHQTIVPSSVVAPG--AVRLQSVQS 307
Query 286 HILMKVETHNHPTAISPFAGAATGSGGEIRDEGATGRGGKPKAGLTGFTVSNLNIPGFEQ 345
++ ETHN PTA++PF+GA TG+GG +RD GRGG P AG G+ V L+IPG++Q
Sbjct 308 DLIFTAETHNMPTAVAPFSGATTGTGGRLRDVQGVGRGGVPIAGTAGYCVGALHIPGYKQ 367
Query 346 PWEE-NYGKPSRMASPLQIMIEGPLGGAAFNNEFGRPALNGYFRTFEQNVNGEVKG---F 401
P+E ++ P+ A PLQ++IE G + + N+FG P ++G+ ++ N + +
Sbjct 368 PYEPLDFKYPATFAPPLQVLIEASNGASDYGNKFGEPVISGFALSYGLNSAADASQRDEY 427
Query 402 HKPIMIAGGYGNIRPDHVEKDAIQPGDLLIVLGGPAMLIGLGGGAASSVDSGTMGES-LD 460
KPIM +GG G + EK G LL +GGP IG+GGGAASSV+ G++ LD
Sbjct 428 VKPIMFSGGLGTMPATMREKLPPARGQLLAKIGGPVYRIGVGGGAASSVEIQGSGDAELD 487
Query 461 FASVQRENPEMERRCQEVIDTCWRLEDFNPIVSVHDVGAGGLSNAMPELVNDHELGAILN 520
F +VQR + EME + V+ C L + NPI+++HD GAGG N + ELV GA++
Sbjct 488 FNAVQRGDAEMENKLNRVVRACLDLGEQNPILAIHDQGAGGNGNVLKELVEPGFAGAVIF 547
Query 521 LRKIPSLEPGMSPMEIWSNEAQERYVLAIRPESLAQFEEICARERCPFAVLGEAT-EARH 579
++ +P ++ +E+W E QE + + E+IC RERCP + +G T + R
Sbjct 548 SKEFQLGDPTITALELWGAEYQENNAILCNADQRELLEKICRRERCPISFVGVVTGDGRV 607
Query 580 LTVEDPL-------------FENNAVDIPMQVMLGGTPRMQRSYESIEREGTPFDTTQID 626
+E P E + D+ ++ +LG P+ R+Y+ ++RE TP +
Sbjct 608 TLLEKPAPKDLEQALNASNRSEVSPFDLELKYVLGDMPK--RTYD-LKREQTPLKELSLP 664
Query 627 ----LKDAIFRVLKNPTVASKSFLITIGDRSITGMVARDQMVGPWQVPVADAAVTTTSLQ 682
L +A+ RVL V SK FL DR + G++A+ Q VGP Q P+AD A+TT S
Sbjct 665 KGLLLDEALERVLSLVAVGSKRFLTNKVDRCVGGLIAQQQCVGPLQAPLADYALTTVSHF 724
Query 683 GYTGEAMAMGERPPVALLNPAASARLAVAEAITNIASANIEQIGDIKLSANWMAAAGQKG 742
++G A ++G +P LL+PAA AR+ VAEA++N+ I ++ D+K S NWM AA G
Sbjct 725 SHSGIATSIGTQPLKGLLDPAAMARMCVAEALSNLVFVKISELADVKCSGNWMWAAKLPG 784
Query 743 EDQALFEGVKAIGMEMCPALGIAIPVGKDSLSMRTTWNDDGEDKAVTSPMSGVITAFAPV 802
E +F+ K + ++ L IAI GKDSLSM + + SP + VI+ +AP
Sbjct 785 EGARMFDACKEL-CQILEELHIAIDGGKDSLSMAAKVGGE----TIKSPGTLVISTYAPC 839
Query 803 SDVRKTLTPELK---KFDESVLVRIDLSKGQFRLGASILTQVYKAIGTVTPDVDSFDDLK 859
DVR +TP+LK ++ L+ I+L RLG S L Q Y G TP++ D L
Sbjct 840 PDVRLKVTPDLKGPGAGSKTSLLWINLENSA-RLGGSALAQAYAQQGKDTPNLTRSDVLG 898
Query 860 AFFALVQDWNNRSLIQAYHDIGDGGLLATVAEMMFASRLGVAFE-----------QQSIE 908
FA+ Q LIQA HD+ DGGLL V EM G+ + +S+E
Sbjct 899 KAFAVTQSLLGDGLIQAGHDVSDGGLLVCVLEMAIGGLSGLRVDLSEPLAKLKNFDKSVE 958
Query 909 SL--------FAEEIGAVVQLKAADWDAVQAEIAASGLKDAISVVGRVNSSDQLSV--NG 958
L FAEE G VV++ D + V++ +G+ + V D V NG
Sbjct 959 KLNRPELAVLFAEECGWVVEVLDTDLERVRSTYEKAGVPNYYLGVTEGFGLDSRVVLKNG 1018
Query 959 ----LTFERAELQRAWAEVSHQIQRLRDNVETADQEFALISDQNHKGLIAQATFDLNEPV 1014
L L + W S+++++L+ N E A+ E+ + + Q N
Sbjct 1019 KSELLDQPLRVLYKKWERTSYELEKLQANPECAEAEYNSLEYRQ----APQYRGPQNVQA 1074
Query 1015 EAPFIATRRP-NMAILREQGVNGHVEMAAAFDKVGFNTIDVHMSDLLAGRVDLQDFEGLV 1073
E + P +A+LRE+GVN EM A + F DV MSDLL G + + GL+
Sbjct 1075 ELTLKRSSAPVRVAVLREEGVNSEREMMACLLRANFEVHDVTMSDLLQGTASVSQYRGLI 1134
Query 1074 ACGGFSYGDVMGAGGGWAKSVLFNPKLRDQFESFFHRDSTFSLGICNGCQMLSQL----- 1128
GGFSY D +G+ GWA ++L NP+L QFE+F R FSLGICNGCQ+++ +
Sbjct 1135 FPGGFSYADTLGSAKGWAANILHNPRLLPQFEAFKRRQDVFSLGICNGCQLMTLIGFVGS 1194
Query 1129 APLIPGADAWPRFHRNVSEVFEARSVNVRVEKSVSVLLQDMQGSILPIAVAHGEGRVVTT 1188
A GAD N S+ FE R V++ + S++L M+ +L VAHGEGR
Sbjct 1195 AKSEVGADPDVALLHNKSQRFECRWATVKIPSNRSIMLGSMKDLVLGCWVAHGEGRFAFR 1254
Query 1189 DAHLAS-LNANQQVTLRYVDSLGNPTQHYPLNPNGSPEAVTGVTSKDGRATIMMPHPERN 1247
D L S L + Q VTL+YVD +G PT+ YPLNPNGSP+ + G+ S DGR +MPHPER
Sbjct 1255 DEKLISHLQSEQLVTLQYVDDVGKPTELYPLNPNGSPQGIAGLCSSDGRHLALMPHPERC 1314
Query 1248 FRAIQHSWSPENW-----TEDGAWLRMFRNA 1273
Q + P ++ + W MF NA
Sbjct 1315 SSMYQWPYVPSSFEVSPTQSESPWQIMFNNA 1345
>P11282 Probable membrane antigen 75 [Saimiriine herpesvirus 2
(strain 11)]
Length=1299
Score = 163 bits (413), Expect = 3e-43
Identities = 198/752 (26%), Positives = 315/752 (42%), Gaps = 113/752 (15%)
Query 573 EATEARHLTVEDPLFENNAVDIPMQVMLGGTPRMQRSYESIEREGTPFDTTQIDLKDAIF 632
+AT + LTV+ P ++ T + Q +E E D I
Sbjct 564 QATSSMTLTVQ-----------PHASVVSATLQPQEPHE----EDESIDWAMFGTSSTIS 608
Query 633 RVLKNPTVASKSFLITIGDRSITGMVARDQMVGPWQVPVADAAVTTTS------------ 680
+L +P VASKS +I DR G++A+ +GP PV+D A+ S
Sbjct 609 NILSHPAVASKSNIIRRLDRCGNGLIAQQPGIGPSDAPVSDYAIICDSSMFPARLENDAQ 668
Query 681 ---------------------------LQGYTGEAMAMGERPPVALLNPAASARLAVAEA 713
L + + +A+GE+ NP + A+AEA
Sbjct 669 SIKKISKQEAQRAYAQIHKWFGTEKLFLNTISAKVIALGEQAYKLSRNPIVGVKYAIAEA 728
Query 714 ITNIASANIEQIGDIKLSANWMAAAGQKGEDQALFEGVKAIGMEMCPALGIAIPVGKDSL 773
ITNI + DI L+ +AA K E AL+ + A EMC L + + + S
Sbjct 729 ITNIMFGPDCVLEDITLT---VAAHWNKQETAALYRVLFAC-KEMCRELNVNLSITDASD 784
Query 774 SMRTTWNDDGEDKAVTSPMSGVITAFAPVSDVRKTLTPELKKFDESVLVRIDLSKGQFRL 833
S T D V V+TA A V+ + + +TP LKK E+ LV + LSK + L
Sbjct 785 SRDTPIQDTDAANTV------VVTASARVTSIER-ITPALKKA-ENALVHVCLSK-ELTL 835
Query 834 GASILTQVYKAIGTVTPDVDSFDDLKAFFALVQDWNNRSLIQAYHDIGDGGLLATVAEMM 893
S+ + A + PD+D+ L+ F V+ +++L+ A HDI DGGL+ T AEM
Sbjct 836 SGSVFENSFTAFSSHLPDLDT-SKLRDMFYAVKHLISKNLVVAGHDISDGGLITTAAEMC 894
Query 894 FASRLGVAFEQQS----IESLFAEEIGAVVQLKAADWDAVQAEIAASGLKDAISVVGRVN 949
FAS GV S + L +E GA++++ V ++ GL VG VN
Sbjct 895 FASTFGVTVNLPSALPALMYLVSETPGALLEVPKEHLSTVTTLLSERGL--TWYAVGTVN 952
Query 950 SSDQLSV--NG---LTFERAELQRAWAEVSHQIQRLRDNVETADQ--EFALISDQNHKGL 1002
+ LS+ NG LT L W + ++ ET + E +D + +
Sbjct 953 NVKNLSIYDNGTHLLTESINILNSKWMSYA------EESFETCEPHIESMYRNDYGNNAM 1006
Query 1003 IAQATFDL--NEPVEAPFIATRRPNMAILREQGVNGHVEMAAAFDKVGFNTIDVHMSDLL 1060
+ DL ++P++ + ++A+L G V AF VGF + + LL
Sbjct 1007 DLKHLEDLCTHKPLQLYTCPSHPVSVAVLTFPGCPDPVATLQAFANVGFLSYPISTEFLL 1066
Query 1061 AGRVDLQDFEGLVACGGFSYGDVMGAGGGWAKSVLFNPKL-RDQFESFFHRDSTFSL--- 1116
G +L F L G ++ + G G A L L ++ + FF R T SL
Sbjct 1067 QGN-NLNAFSCLAVSGSSAF-EEEGTGTRIAIYTLLQCDLAKNCLKEFFQRPDTLSLCCG 1124
Query 1117 ----GICNGCQMLSQLAP----LIPGADAWP-RFHRNVSEVFEARSVNVRVEKSV-SVLL 1166
+ CQ++ P + ++W N S+ +E+ +N V ++ S++L
Sbjct 1125 ELGTQLLAACQVVGDTHPSRGDISSNPESWTLELEPNASKHYESLWLNFHVPQTTKSIIL 1184
Query 1167 QDMQGSILPIAVAHGEGRVVTTDAHLASLNANQQVTLRYVDSLGNP---TQHYPLNPNGS 1223
Q ++G+I + G DA + N + + Y + NP HYP NP+G+
Sbjct 1185 QALRGTIFQDGLWQVLGLRYKHDAQEYIMQQNGTIAMSYHSAKINPYLYAMHYPRNPSGN 1244
Query 1224 PEAVTGVTSKDGRATIMMPHPERNFRAIQHSW 1255
+V G+ SK+GR ++ P +F H+W
Sbjct 1245 -SSVAGICSKNGRHLALLVEPALSF----HTW 1271
Score = 26.9 bits (58), Expect = 0.22
Identities = 25/134 (19%), Positives = 54/134 (40%), Gaps = 9/134 (7%)
Query 452 SGTMGESLDFASVQRENPEMER-RCQEVIDTCWRLEDFNPIVSVHDVGAGGLSNAMPELV 510
SG++ E+ F + P+++ + +++ L N +V+ HD+ GGL E+
Sbjct 836 SGSVFEN-SFTAFSSHLPDLDTSKLRDMFYAVKHLISKNLVVAGHDISDGGLITTAAEMC 894
Query 511 NDHELGAILNLRKIPSLEPGMSPMEIWSNEAQERYVLAIRPESLAQFEEICARERCPFAV 570
G +NL P P ++ +L + E L+ + + +
Sbjct 895 FASTFGVTVNL-------PSALPALMYLVSETPGALLEVPKEHLSTVTTLLSERGLTWYA 947
Query 571 LGEATEARHLTVED 584
+G ++L++ D
Sbjct 948 VGTVNNVKNLSIYD 961
>Q5SMH8 Phosphoribosylformylglycinamidine synthase subunit PurL
[Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)]
Length=725
Score = 154 bits (390), Expect = 3e-41
Identities = 191/737 (26%), Positives = 310/737 (42%), Gaps = 114/737 (15%)
Query 190 QLGRNPNDIELMMFAQANSEHCRHKIFGSEWTIDGEVQPLSLFQMIKNTYKESPDEVLSA 249
+LGR PN +EL++F SEHC +K +PL +K KE + VL
Sbjct 21 RLGREPNRVELLLFKVMWSEHCAYK----------NSRPL-----LKALPKEG-EAVLQG 64
Query 250 YKDNASVI-VGYDTQRFYPKKDNDTGHYIYKYKSQAAHILMKVETHNHPTAISPFAGAAT 308
+NA V+ VG + + K+E+HNHP+A+ PF GAAT
Sbjct 65 PGENAGVVRVG-----------------------EGWAVAFKIESHNHPSAVEPFQGAAT 101
Query 309 GSGGEIRDEGATGRGGKPKAGLTGFTVSNLNIPGFEQPWEENYGKPSRMASPLQIMIEGP 368
G GG +RD G +P A L +G P S + +++G
Sbjct 102 GVGGILRD--IMSMGARPIALLDSL----------------RFGPPEEARS--RYLLKGV 141
Query 369 LGGAAF-NNEFGRPALNG--YFRTFEQNVNGEVKGFHK-PIMIAGGYGNIRPDHVEKDAI 424
+ G AF N G P + G YF +G+ + P++ A G +R +H+++
Sbjct 142 VSGIAFYGNAIGVPTVGGDLYFH----------EGYRENPLVNAMCLGLLREEHLKRSRA 191
Query 425 QPGDLLIVLGGPAMLIGLGGGAASSVDSGTMGESLDFASVQRENPEMERRCQEVIDTCWR 484
G + G G+GG A +S + ++ D +VQ +P + + E
Sbjct 192 SLGRPIYYAGAKTGRDGIGGAAFASRELKEE-KAEDRPAVQVGDPFLGKLLMEATLEAIE 250
Query 485 LEDFNPIVSVHDVGAGGLSNAMPELVNDHELGAILNLRKIPSLEPGMSPMEIWSNEAQER 544
L+ + V D+GA GL++++ EL + LG L+L +P+ E GM+P E+ +E+QER
Sbjct 251 LD---LVEGVQDMGAAGLTSSLSELAHKSGLGVELHLDLVPTREEGMTPEELLLSESQER 307
Query 545 YVLAIRPESLAQFEEICARERCPFAVLGEATEARHLTVEDPLFENNAV-DIPMQVMLGGT 603
VL + EE+ R + R V LF V ++P + +
Sbjct 308 MVLVPKEGKEKALEEVFGRWGLDCVPVARTIPERVFRV---LFRGEVVAEVPTEALAEAP 364
Query 604 P--RMQRSYESIER-EGTPFDTTQIDLKDAIFRVLKNPTVASKSFLITIGDRSITGMVAR 660
R+ R + R TP + D ++ + R+L +P +AS+ + D + A
Sbjct 365 TYVRVGREDPEVRRLRETPIPPLEADPQEVLRRLLASPNLASREAVYERYDHQVGTRTA- 423
Query 661 DQMVGPWQVPVADAAVTTTSLQGYTGEAMAMGERPPVALLNPAASARLAVAEAITNIASA 720
+ P + A + T L G A + + P + L+P A A+AEA N++
Sbjct 424 ---LLPGKGDAAVLWIKGTRL----GVAAKVDQNPRYSRLHPRLGAMHALAEACRNVS-- 474
Query 721 NIEQIGDIKLSANWMAAAGQKGEDQALFEGVKAIG--MEMCPALGIAIPVGKDSLSMRTT 778
+G L+ G + E + I E ALG+ + G SL
Sbjct 475 ---VVGAKPLAYTDGLNLGSPETPEGYHELAETIAGLKEASEALGVPVVSGNVSL----- 526
Query 779 WNDDGEDKAVTSPMSGVITAFAPVSDVRKTLTPELKKFDESVLVRIDLSKGQFRLGASIL 838
+N+ G + + M GV+ V +V K ++ E VL+ I +G+ LGAS +
Sbjct 527 YNESGGKRIPPTAMVGVV----GVLEVDKRAEMGFRRPGE-VLLLIGEERGE--LGASEV 579
Query 839 TQVYKAIGTVTPDVDSFDDLKAFFALVQDWNNRSLIQAYHDIGDGGLLATVAEMMFASRL 898
+ P KA ++D R L + HD+ +GGLL +AEM F +
Sbjct 580 LYLLTGKEFGHPPRLDLGREKAVQEAIRDLIQRGLTRTAHDVAEGGLLLALAEMTFPYGV 639
Query 899 GVAFE--QQSIESLFAE 913
G E ++ +E+LF E
Sbjct 640 GATVEVREEGLEALFGE 656
>P26500 Phosphoribosylformylglycinamidine synthase subunit PurL
[Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM
2133 / JCM 14651 / NBRC 100331 / OCM 82 / Marburg)]
Length=714
Score = 152 bits (384), Expect = 2e-40
Identities = 187/762 (25%), Positives = 321/762 (42%), Gaps = 123/762 (16%)
Query 176 LSEQEIDYLTDAFTQLGRNPNDIELMMFAQANSEHCRHKIFGSEWTIDGEVQPLSLFQMI 235
L++ EI+++ +LGR+PN +E M SEHC +K
Sbjct 3 LTDSEIEFIRK---ELGRDPNPLEYGMLDVMFSEHCSYK--------------------- 38
Query 236 KNTYKESPDEVLSAYK-DNASVIVGYDTQRFYPKKDNDTGHYIYKYKSQAAHILMKVETH 294
S VL + + VI+G +D G + + + A + + +E+H
Sbjct 39 ------SSRPVLGFFPTEGEGVIIG---------PGDDAG--VVEVTDELA-MAIGIESH 80
Query 295 NHPTAISPFAGAATGSGGEIRDEGATGRGGKPKAGLTGFTVSNLNIPGFEQPWEENYGKP 354
NHP+AI P+ GA TG GG +RD G P A L G+ + + Y
Sbjct 81 NHPSAIEPYGGAGTGIGGILRD--IISMGAMPIALLDSLRF------GYLEDQKSRY--- 129
Query 355 SRMASPLQIMIEGPLGGAA-FNNEFGRPALNGYFRTFEQNVNGEVKGFHKPIMIAGGYGN 413
+ E + G + + N G P + G F+ N P++ G
Sbjct 130 ---------LFEHVVKGISDYGNRVGVPTVAGEVE-FDDNFQ------LNPLVNVMCAGL 173
Query 414 IRPDHVEKD-AIQPGDLLIVLGGPAMLIGLGGGAASSVDSGTMGESLDFASVQRENPEME 472
+R D +++ A +PGD+ +++GG G+ G +S + + E D +VQ +P +
Sbjct 174 VRKDEIKRGIAPRPGDVFLLMGGRTGRDGIHGVTFASEELTSSSELEDRPAVQVGDPFTK 233
Query 473 RRCQEVIDTCWRLEDFNPIVSVHDVGAGGLSNAMPELVNDHELGAILNLRKIPSLEPGMS 532
+ V++ + + + + V D+G GGL+ + ELV + GA +NL IP E GM+
Sbjct 234 KM---VMEASFEIMEKIEVSGVKDLGGGGLTCCISELVAKCDNGARVNLEAIPLREEGMT 290
Query 533 PMEIWSNEAQERYVLAIRPESLAQFEEICARERCPFAVLGEATEARHLTVEDPLFENNAV 592
P EI +E+QER + + P+ + + EIC + P AV+GE T+ + VE E +
Sbjct 291 PYEIMLSESQERMIFVLSPDRVDEAMEICRKYELPAAVIGEVTDTGRMIVES---EGKVI 347
Query 593 -DIPMQVMLGGTPRMQRSYESIEREGTPFDTTQIDLKDAIFRVLKNPTVASKSFLITIGD 651
D+P + +L P ++R + + + L +A+ ++L +P +ASK ++ D
Sbjct 348 ADLPAK-LLADPPVIEREAKKPDLPEGQVEVQHPLLTEALLKLLSSPNIASKRWVYRQYD 406
Query 652 RSITGMVARDQMVGPWQVPVADAAVTTTSLQGYTGEAMAMGERPPVALLNPAASARLAVA 711
+ + P DAAV + TG A+ + L+P +V
Sbjct 407 HEV--------QIRTVVKPGDDAAVLRVDEK--TGVALTVDCNSIHTKLDPYGGGAASVG 456
Query 712 EAITNIASANIEQIGDIKLSANWMAAAGQKGEDQALFEGVKAI-GM-EMCPALGIAIPVG 769
EAI N+ S +G L G + + ++ + + GM +M G + G
Sbjct 457 EAIRNVVS-----MGAWPLCIVDCLNFGNPEKPEVFWQFRECVRGMADMAETFGTPVISG 511
Query 770 KDSLSMRTTWNDDGEDKAVTSPMSGVITAFAPVSDVRKTLTPELKKFDESVLVRIDLSKG 829
S +N+ SP+ GV P+ ++ T + K E ++V D
Sbjct 512 NVSF-----YNETEGVTVNPSPVVGV-AGRLPLDSIK---TMDFKAEGEKIIVIGDTKP- 561
Query 830 QFRLGAS-ILTQVYKAIGTVTPDVD---SFDDLKAFFALVQDWNNRSLIQAYHDIGDGGL 885
LGAS L V+ + P+ D FD + +++ + ++ + A HD GG+
Sbjct 562 --ELGASEYLRTVHGIVDGKPPETDLRAEFDAANSVRRIIERFGDK--VTAIHDCSAGGI 617
Query 886 LATVAEMMFASRLGVAFEQQSI--------ESLFAEEIGAVV 919
VAEM S +G + I E+LF+E G +
Sbjct 618 GVAVAEMAIKSGIGATIDTGKIPGSFSNIHEALFSESNGRYI 659
>P9WHL7 Phosphoribosylformylglycinamidine synthase subunit PurL
[Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)]
Length=766
Score = 150 bits (378), Expect = 1e-39
Identities = 187/789 (24%), Positives = 312/789 (40%), Gaps = 110/789 (14%)
Query 191 LGRNPNDIELMMFAQANSEHCRHKIFGSEWTIDGEVQPLSLFQMIKNTYKESPDEVLSAY 250
LGR P D EL M++ SEHC +K GE T E +L+
Sbjct 47 LGRRPTDTELAMYSVMWSEHCSYKSSKVHLRYFGET-----------TSDEMRAAMLAGI 95
Query 251 KDNASVIVGYDTQRFYPKKDNDTGHYIYKYKSQAAHILMKVETHNHPTAISPFAGAATGS 310
+NA V+ D G + KVE+HNHP+ + P+ GAATG
Sbjct 96 GENAGVV--------------DIG--------DGWAVTFKVESHNHPSYVEPYQGAATGV 133
Query 311 GGEIRDEGATGRGGKPKAGLTGFTVSNLNIPGFEQPWEENYGKPSRMASPLQIMIEGPLG 370
GG +RD A G +P A + + P + +++G +
Sbjct 134 GGIVRDIMAMG--ARPVAVMDQLRFGAADAPDTRR------------------VLDGVVR 173
Query 371 G-AAFNNEFGRPALNGYFRTFEQNVNGEVKGFHKPIMIAGGYGNIRPDHVEKD-AIQPGD 428
G + N G P + G F+ G P++ A G +R + + A G+
Sbjct 174 GIGGYGNSLGLPNIGGE-TVFDPCYAGN------PLVNALCVGVLRQEDLHLAFASGAGN 226
Query 429 LLIVLGGPAMLIGLGGGAASSVDS-GTMGESLDFASVQRENPEMERRCQEVIDTCWRLED 487
+I+ G L G+GG + + D+ G SVQ +P ME+ +I+ C L
Sbjct 227 KIILFGARTGLDGIGGVSVLASDTFDAEGSRKKLPSVQVGDPFMEK---VLIECCLELYA 283
Query 488 FNPIVSVHDVGAGGLSNAMPELVNDHELGAILNLRKIPSLEPGMSPMEIWSNEAQERYVL 547
++ + D+G GLS A EL + + G + L +P M+P E+ +E+QER
Sbjct 284 GGLVIGIQDLGGAGLSCATSELASAGDGGMTIQLDSVPLRAKEMTPAEVLCSESQERMCA 343
Query 548 AIRPESLAQFEEICARERCPFAVLGEATEARHLTVEDPLFENNAVDIPMQVMLGGTPRMQ 607
+ P+++ F +C + V+GE T+ L + VD+P + + P Q
Sbjct 344 VVSPKNVDAFLAVCRKWEVLATVIGEVTDGDRLQI--TWHGETVVDVPPRTVAHEGPVYQ 401
Query 608 RSYESIEREGT---------PFDTTQIDLKDAIFRVLKNPTVASKSFLITIGDRSITGMV 658
R + + T +L+ + +L +P + S++F+ DR + G
Sbjct 402 RPVARPDTQDALNADRSAKLSRPVTGDELRATLLALLGSPHLCSRAFITEQYDRYVRGNT 461
Query 659 ARDQMVGPWQVPVADAAVTTTSLQGYTGEAMAMGERPPVALLNPAASARLAVAEAITNIA 718
+ AD + G A++ LL+P A A+LA+AEA N+A
Sbjct 462 VLAEH--------ADGGMLRIDESTGRGIAVSTDASGRYTLLDPYAGAQLALAEAYRNVA 513
Query 719 SANIEQIGDIKLSANWMAAAGQKGEDQALFEGVKAIG--MEMCPALGIAIPVGKDSLSMR 776
G ++ G + +++ +A+ + C LGI + G S
Sbjct 514 VT-----GATPVAVTNCLNFGSPEDPGVMWQFTQAVRGLADGCADLGIPVTGGNVSF--- 565
Query 777 TTWNDDGEDKAVTSPMSGVITAFAPVSDVRKTLTPELKKFDESVLVRIDLSKGQFRLGAS 836
+N G + +P+ GV+ + DVR+ + L L+ + ++ +F S
Sbjct 566 --YNQTGSAAILPTPVVGVL---GVIDDVRRRIPTGLGAEPGETLMLLGDTRDEF--DGS 618
Query 837 ILTQV-YKAIGTVTPDVDSFDDLKAFFALVQDWNNRSLIQAYHDIGDGGLLATVAEMMFA 895
+ QV +G + P VD + K A++ + L+ A HD+ +GGL + E A
Sbjct 619 VWAQVTADHLGGLPPVVDLARE-KLLAAVLSSASRDGLVSAAHDLSEGGLAQAIVESALA 677
Query 896 SRLGVAF----EQQSIESLFAEEIGAV-VQLKAADWDAVQAEIAASGLKDAISVVGRVNS 950
G LF+E G V V + + + A GL A+ +
Sbjct 678 GETGCRIVLPEGADPFVLLFSESAGRVLVAVPRTEESRFRGMCEARGL-PAVRIGVVDQG 736
Query 951 SDQLSVNGL 959
SD + V GL
Sbjct 737 SDAVEVQGL 745
Score = 22.3 bits (46), Expect = 5.5
Identities = 12/34 (35%), Positives = 18/34 (53%), Gaps = 0/34 (0%)
Query 1157 RVEKSVSVLLQDMQGSILPIAVAHGEGRVVTTDA 1190
R + +VL + G +L I + G G V+TDA
Sbjct 455 RYVRGNTVLAEHADGGMLRIDESTGRGIAVSTDA 488
Lambda K H a alpha
0.318 0.134 0.392 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 29438090
Database: 8e3b3e160857ad9d334e6a2510b4f137.SwissProt.fasta
Posted date: May 20, 2024 3:53 AM
Number of letters in database: 25,778
Number of sequences in database: 21
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
Loading
Data ...
