BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 31885700b0962e39ed22cdd4c7022849.SwissProt.fasta
11 sequences; 9,032 total letters
Query= ACIAD2635
Length=210
Score E
Sequences producing significant alignments: (Bits) Value
Q64737 Phosphoribosylamine--glycine ligase / Phosphoribosylformyl... 188 3e-58
P08179 Phosphoribosylglycinamide formyltransferase [Escherichia c... 174 3e-58
P22102 Phosphoribosylamine--glycine ligase / Phosphoribosylformyl... 182 2e-56
P43846 Phosphoribosylglycinamide formyltransferase [Haemophilus i... 169 4e-56
Q59A32 Phosphoribosylamine--glycine ligase / Phosphoribosylformyl... 181 8e-56
Q26255 Phosphoribosylamine--glycine ligase / Phosphoribosylformyl... 181 1e-55
P21872 Phosphoribosylamine--glycine ligase / Phosphoribosylformyl... 175 1e-53
P00967 Phosphoribosylamine--glycine ligase / Phosphoribosylformyl... 165 3e-50
P16340 Phosphoribosylamine--glycine ligase / Phosphoribosylformyl... 163 1e-49
P12040 Phosphoribosylglycinamide formyltransferase [Bacillus subt... 140 2e-45
P52422 Phosphoribosylglycinamide formyltransferase, chloroplastic... 112 4e-33
>Q64737 Phosphoribosylamine--glycine ligase / Phosphoribosylformylglycinamidine
cyclo-ligase / Phosphoribosylglycinamide formyltransferase
[Mus musculus]
Length=1010
Score = 188 bits (477), Expect = 3e-58
Identities = 97/193 (50%), Positives = 130/193 (67%), Gaps = 4/193 (2%)
Query 3 KIAVLVSGNGSNLQALIDANL----SGSIVGVISNKPDAYALKRAEQANIQTKVIEHKTY 58
++AVL+SG GSNLQALID+ S IV VISNK L RAE+A I T+VI HK Y
Sbjct 809 RVAVLISGTGSNLQALIDSTRDPKSSSHIVLVISNKAAVAGLDRAERAGIPTRVINHKLY 868
Query 59 PTRELFDDAMHQQLIEWNIDLVVLAGFMRILSEKFVRQWQGKMINIHPSLLPLYKGMHTH 118
R FD+A+ L E+++D+V LAGFMRILS FVR+W GKM+NIHPSLLP +KG + H
Sbjct 869 KNRVEFDNAVDHVLEEFSVDIVCLAGFMRILSGPFVRKWDGKMLNIHPSLLPSFKGSNAH 928
Query 119 QRVLNTGDVYHGCTVHYVTAELDAGPSLLQGVLKVEQHDTVATLANRIHELEHVIYPQVV 178
++VL G GCTVH+V ++DAG +LQ + V + DTVATL+ R+ EH I+P +
Sbjct 929 EQVLEAGVTITGCTVHFVAEDVDAGQIILQEAVPVRRGDTVATLSERVKVAEHKIFPAAL 988
Query 179 EWICTNIIQYQSD 191
+ + + +Q + D
Sbjct 989 QLVASGAVQLRED 1001
>P08179 Phosphoribosylglycinamide formyltransferase [Escherichia
coli (strain K12)]
Length=212
Score = 174 bits (441), Expect = 3e-58
Identities = 89/203 (44%), Positives = 125/203 (62%), Gaps = 4/203 (2%)
Query 2 IKIAVLVSGNGSNLQALIDA----NLSGSIVGVISNKPDAYALKRAEQANIQTKVIEHKT 57
+ I VL+SGNGSNLQA+IDA + G++ V SNK DA+ L+RA QA I T +
Sbjct 1 MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASA 60
Query 58 YPTRELFDDAMHQQLIEWNIDLVVLAGFMRILSEKFVRQWQGKMINIHPSLLPLYKGMHT 117
+ +RE +D + ++ + D+VVLAGFMRILS FV + G+++NIHPSLLP Y G+HT
Sbjct 61 FDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHT 120
Query 118 HQRVLNTGDVYHGCTVHYVTAELDAGPSLLQGVLKVEQHDTVATLANRIHELEHVIYPQV 177
H++ L GD HG +VH+VT ELD GP +LQ + V D+ + R+ EH IYP V
Sbjct 121 HRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGDSEDDITARVQTQEHAIYPLV 180
Query 178 VEWICTNIIQYQSDQVLLKGKPL 200
+ W ++ + L G+ L
Sbjct 181 ISWFADGRLKMHENAAWLDGQRL 203
>P22102 Phosphoribosylamine--glycine ligase / Phosphoribosylformylglycinamidine
cyclo-ligase / Phosphoribosylglycinamide formyltransferase
[Homo sapiens]
Length=1010
Score = 182 bits (463), Expect = 2e-56
Identities = 95/189 (50%), Positives = 128/189 (68%), Gaps = 4/189 (2%)
Query 3 KIAVLVSGNGSNLQALIDA----NLSGSIVGVISNKPDAYALKRAEQANIQTKVIEHKTY 58
++AVL+SG GSNLQALID+ N S I VISNK L +AE+A I T+VI HK Y
Sbjct 809 RVAVLISGTGSNLQALIDSTREPNSSAQIDIVISNKAAVAGLDKAERAGIPTRVINHKLY 868
Query 59 PTRELFDDAMHQQLIEWNIDLVVLAGFMRILSEKFVRQWQGKMINIHPSLLPLYKGMHTH 118
R FD A+ L E++ID+V LAGFMRILS FV++W GKM+NIHPSLLP +KG + H
Sbjct 869 KNRVEFDSAIDLVLEEFSIDIVCLAGFMRILSGPFVQKWNGKMLNIHPSLLPSFKGSNAH 928
Query 119 QRVLNTGDVYHGCTVHYVTAELDAGPSLLQGVLKVEQHDTVATLANRIHELEHVIYPQVV 178
++ L TG GCTVH+V ++DAG +LQ + V++ DTVATL+ R+ EH I+P +
Sbjct 929 EQALETGVTVTGCTVHFVAEDVDAGQIILQEAVPVKRGDTVATLSERVKLAEHKIFPAAL 988
Query 179 EWICTNIIQ 187
+ + + +Q
Sbjct 989 QLVASGTVQ 997
>P43846 Phosphoribosylglycinamide formyltransferase [Haemophilus
influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)]
Length=212
Score = 169 bits (427), Expect = 4e-56
Identities = 91/206 (44%), Positives = 126/206 (61%), Gaps = 4/206 (2%)
Query 1 MIKIAVLVSGNGSNLQALIDANLSGSIVG----VISNKPDAYALKRAEQANIQTKVIEHK 56
M KIAVL+SG G+NLQ +IDA SG I VISNK DAY L RA+QA I V K
Sbjct 1 MKKIAVLISGQGTNLQTIIDACHSGDIPAKIACVISNKADAYGLVRAKQAQIPQAVFLRK 60
Query 57 TYPTRELFDDAMHQQLIEWNIDLVVLAGFMRILSEKFVRQWQGKMINIHPSLLPLYKGMH 116
+ DDA+ L +DL+VLAG+M+IL+ KF +++ GK++NIHPSLLP Y G++
Sbjct 61 NFSNNLEMDDAIGDYLQSLAVDLIVLAGYMKILTPKFTQRFAGKILNIHPSLLPKYAGLN 120
Query 117 THQRVLNTGDVYHGCTVHYVTAELDAGPSLLQGVLKVEQHDTVATLANRIHELEHVIYPQ 176
T+QR + GD HG TVH+V E+D G +LQ + + D++ + R E E+ IYP
Sbjct 121 TYQRAIEAGDNEHGTTVHFVNEEVDGGAIVLQAKVPIFPEDSIEEVEARTREQEYQIYPL 180
Query 177 VVEWICTNIIQYQSDQVLLKGKPLLK 202
V++W ++ + + L GK L K
Sbjct 181 VIKWFTEGRLRLKDNLAYLDGKALPK 206
>Q59A32 Phosphoribosylamine--glycine ligase / Phosphoribosylformylglycinamidine
cyclo-ligase / Phosphoribosylglycinamide formyltransferase
[Bos taurus]
Length=1010
Score = 181 bits (459), Expect = 8e-56
Identities = 93/189 (49%), Positives = 128/189 (68%), Gaps = 4/189 (2%)
Query 3 KIAVLVSGNGSNLQALIDANLSGS----IVGVISNKPDAYALKRAEQANIQTKVIEHKTY 58
++AVL+SG GSNLQALID+ S IV VISNK L +AE+A I T+VI HK Y
Sbjct 809 RVAVLISGTGSNLQALIDSTREPSSLAHIVIVISNKAAVAGLDKAEKAGIPTRVINHKLY 868
Query 59 PTRELFDDAMHQQLIEWNIDLVVLAGFMRILSEKFVRQWQGKMINIHPSLLPLYKGMHTH 118
R FD A+ + L E++ D+V LAGFMRILS FVR+W GKM+NIHPSLLP +KG + H
Sbjct 869 KNRAAFDTAIDEVLEEFSTDIVCLAGFMRILSGPFVRKWNGKMLNIHPSLLPSFKGSNAH 928
Query 119 QRVLNTGDVYHGCTVHYVTAELDAGPSLLQGVLKVEQHDTVATLANRIHELEHVIYPQVV 178
++VL+ G GCTVH+V ++DAG +LQ + V++ DTV TL+ R+ EH I+P +
Sbjct 929 EQVLDAGVTVTGCTVHFVAEDVDAGQIILQEAVPVKRGDTVETLSERVKLAEHKIFPSAL 988
Query 179 EWICTNIIQ 187
+ + + ++
Sbjct 989 QLVASGAVR 997
>Q26255 Phosphoribosylamine--glycine ligase / Phosphoribosylformylglycinamidine
cyclo-ligase / Phosphoribosylglycinamide formyltransferase
[Chironomus tentans]
Length=1371
Score = 181 bits (458), Expect = 1e-55
Identities = 87/191 (46%), Positives = 130/191 (68%), Gaps = 6/191 (3%)
Query 3 KIAVLVSGNGSNLQALIDANLS------GSIVGVISNKPDAYALKRAEQANIQTKVIEHK 56
++ VL+SG+GSNLQALIDA S IV V+SNK + L+RA +ANI + VI +K
Sbjct 1171 RVGVLISGSGSNLQALIDATKSTNMGMCSEIVFVLSNKAGIFGLERAAKANIPSTVISNK 1230
Query 57 TYPTRELFDDAMHQQLIEWNIDLVVLAGFMRILSEKFVRQWQGKMINIHPSLLPLYKGMH 116
Y TRE FD A+H +LI+ N++++ LAGFMRIL+ FV +W+GK++NIHPSLLP YKG+
Sbjct 1231 DYATREAFDVALHNELIKHNVEIICLAGFMRILTPCFVNKWKGKLLNIHPSLLPKYKGIT 1290
Query 117 THQRVLNTGDVYHGCTVHYVTAELDAGPSLLQGVLKVEQHDTVATLANRIHELEHVIYPQ 176
+ L +GD GCTVH+V +D G ++Q ++ + ++DTV +L RIH EH+ +P+
Sbjct 1291 AQKDALESGDNESGCTVHFVDENVDTGAIIVQEIVPIFENDTVESLTERIHVAEHIAFPK 1350
Query 177 VVEWICTNIIQ 187
+ + + ++
Sbjct 1351 ALRLVASGYVR 1361
Score = 18.5 bits (36), Expect = 4.1
Identities = 15/65 (23%), Positives = 26/65 (40%), Gaps = 0/65 (0%)
Query 78 DLVVLAGFMRILSEKFVRQWQGKMINIHPSLLPLYKGMHTHQRVLNTGDVYHGCTVHYVT 137
D+ + + + E+F+ + + I P+L Y H D + +T
Sbjct 1015 DIAPFSAYGKTFGEEFLEPTKVYVKEISPALKTGYVKALAHITGGGLWDNIPRVLPYNLT 1074
Query 138 AELDA 142
AELDA
Sbjct 1075 AELDA 1079
>P21872 Phosphoribosylamine--glycine ligase / Phosphoribosylformylglycinamidine
cyclo-ligase / Phosphoribosylglycinamide formyltransferase
[Gallus gallus]
Length=1003
Score = 175 bits (443), Expect = 1e-53
Identities = 87/190 (46%), Positives = 129/190 (68%), Gaps = 4/190 (2%)
Query 2 IKIAVLVSGNGSNLQALIDANLS----GSIVGVISNKPDAYALKRAEQANIQTKVIEHKT 57
+K+AVL+SG G+NL+ALI++ IV V+SNK L++AE+A I T+VI+HK
Sbjct 804 VKVAVLISGTGTNLEALINSTKKPTSFAEIVLVVSNKAGVEGLRKAERAGIPTRVIDHKQ 863
Query 58 YPTRELFDDAMHQQLIEWNIDLVVLAGFMRILSEKFVRQWQGKMINIHPSLLPLYKGMHT 117
Y +R FD A+ + L E++++L+ LAGFMRILS FV++W+GK++NIHPSLLP +KG +
Sbjct 864 YGSRTEFDSAVDRVLEEFSVELICLAGFMRILSGPFVKKWEGKILNIHPSLLPSFKGANA 923
Query 118 HQRVLNTGDVYHGCTVHYVTAELDAGPSLLQGVLKVEQHDTVATLANRIHELEHVIYPQV 177
H+ VL G GCTVH+V E+DAG + Q + V+ DTV TL+ R+ E EH +P
Sbjct 924 HKLVLEAGVRVTGCTVHFVAEEVDAGAIIFQEAVPVKIGDTVETLSERVKEAEHRAFPAA 983
Query 178 VEWICTNIIQ 187
++ + + +Q
Sbjct 984 LQLVASGAVQ 993
>P00967 Phosphoribosylamine--glycine ligase / Phosphoribosylformylglycinamidine
cyclo-ligase / Phosphoribosylglycinamide formyltransferase
[Drosophila melanogaster]
Length=1353
Score = 165 bits (418), Expect = 3e-50
Identities = 81/182 (45%), Positives = 117/182 (64%), Gaps = 6/182 (3%)
Query 3 KIAVLVSGNGSNLQALIDAN------LSGSIVGVISNKPDAYALKRAEQANIQTKVIEHK 56
++AVL+SG GSNLQALIDA + +V VISNKP L+RA QA I + VI HK
Sbjct 1155 RVAVLISGTGSNLQALIDATRDSAQGIHADVVLVISNKPGVLGLQRATQAGIPSLVISHK 1214
Query 57 TYPTRELFDDAMHQQLIEWNIDLVVLAGFMRILSEKFVRQWQGKMINIHPSLLPLYKGMH 116
+ +RE++D + + L +DL+ LAGFMR+LS FVR+W+G+++NIHPSLLP Y G+H
Sbjct 1215 DFASREVYDAELTRNLKAARVDLICLAGFMRVLSAPFVREWRGRLVNIHPSLLPKYPGLH 1274
Query 117 THQRVLNTGDVYHGCTVHYVTAELDAGPSLLQGVLKVEQHDTVATLANRIHELEHVIYPQ 176
++ L G+ GCTVH+V +D G ++Q + + D +L RIH+ EH +P+
Sbjct 1275 VQKQALEAGEKESGCTVHFVDEGVDTGAIIVQAAVPILPDDDEDSLTQRIHKAEHWAFPR 1334
Query 177 VV 178
+
Sbjct 1335 AL 1336
>P16340 Phosphoribosylamine--glycine ligase / Phosphoribosylformylglycinamidine
cyclo-ligase / Phosphoribosylglycinamide formyltransferase
[Drosophila pseudoobscura pseudoobscura]
Length=1364
Score = 163 bits (413), Expect = 1e-49
Identities = 83/195 (43%), Positives = 121/195 (62%), Gaps = 6/195 (3%)
Query 3 KIAVLVSGNGSNLQALIDA------NLSGSIVGVISNKPDAYALKRAEQANIQTKVIEHK 56
++AVL+SG GSNLQALIDA + IV VISNK L+RA +A I + VI HK
Sbjct 1157 RVAVLISGKGSNLQALIDAIRDSAQGVYAEIVLVISNKAGVLGLERAAKAGIPSMVISHK 1216
Query 57 TYPTRELFDDAMHQQLIEWNIDLVVLAGFMRILSEKFVRQWQGKMINIHPSLLPLYKGMH 116
+P+RE++D + + L ++ + LAGFMRILS FVR+W+G++INIHPSLLP + G+H
Sbjct 1217 DFPSREVYDVELTRHLKTARVEFICLAGFMRILSVPFVREWRGRLINIHPSLLPKFPGLH 1276
Query 117 THQRVLNTGDVYHGCTVHYVTAELDAGPSLLQGVLKVEQHDTVATLANRIHELEHVIYPQ 176
++ L G+ GCTVHYV +D G ++Q + + D TL RIH EH +P+
Sbjct 1277 VQKQALEAGETESGCTVHYVDEGVDTGAIIVQAAVPILPGDDEETLTQRIHYAEHWAFPR 1336
Query 177 VVEWICTNIIQYQSD 191
+ + + ++ S+
Sbjct 1337 ALALLASGALRRVSE 1351
Score = 24.3 bits (51), Expect = 0.060
Identities = 14/55 (25%), Positives = 29/55 (53%), Gaps = 1/55 (2%)
Query 5 AVLVSGNGSNLQALIDANLSGSIVGVISNKPDAYALKRAEQA-NIQTKVIEHKTY 58
+VLV G+G A+ ++V I P ++ +++ E+ N+ KV++ K +
Sbjct 4 SVLVIGSGGREHAICWKLSQSTLVKQIYALPGSFGIQQVEKCRNLDAKVLDPKDF 58
>P12040 Phosphoribosylglycinamide formyltransferase [Bacillus
subtilis (strain 168)]
Length=195
Score = 140 bits (354), Expect = 2e-45
Identities = 69/183 (38%), Positives = 111/183 (61%), Gaps = 4/183 (2%)
Query 1 MIKIAVLVSGNGSNLQALI----DANLSGSIVGVISNKPDAYALKRAEQANIQTKVIEHK 56
M K AV SGNGSN +A++ + N S ++ +KP A ++RAE +I + E K
Sbjct 1 MKKFAVFASGNGSNFEAIVTRLKEENWDASAALLVCDKPQAKVIERAEAFHIPSFAFEPK 60
Query 57 TYPTRELFDDAMHQQLIEWNIDLVVLAGFMRILSEKFVRQWQGKMINIHPSLLPLYKGMH 116
+Y + F+ A+ +QL ++L+ LAG+MR++ + ++ + GK+INIHPSLLP + G+
Sbjct 61 SYENKAAFEQAIIEQLRLHEVELIALAGYMRLIGDTLLQAYGGKIINIHPSLLPAFPGID 120
Query 117 THQRVLNTGDVYHGCTVHYVTAELDAGPSLLQGVLKVEQHDTVATLANRIHELEHVIYPQ 176
+ G G TVHYV +D GP + Q +++++HDT+ T+ RIH+LEH YP
Sbjct 121 AVGQAFRAGVKVAGITVHYVDEGMDTGPIIAQKAIEIDEHDTLETIEQRIHKLEHKWYPS 180
Query 177 VVE 179
V++
Sbjct 181 VIK 183
>P52422 Phosphoribosylglycinamide formyltransferase, chloroplastic
[Arabidopsis thaliana]
Length=292
Score = 112 bits (279), Expect = 4e-33
Identities = 67/203 (33%), Positives = 112/203 (55%), Gaps = 10/203 (5%)
Query 3 KIAVLVSGNGSNLQAL----IDANLSGSIVGVISNKPDAYALKRAEQANIQTKVI-EHKT 57
K+AV VSG GSN + + D +++G +V +++NK D + A I V + K
Sbjct 79 KLAVFVSGGGSNFRKIHEGCSDGSVNGDVVLLVTNKKDCGGAEYARSNGIPVLVFPKAKR 138
Query 58 YPTRELFDDAMHQQLIEWNIDLVVLAGFMRILSEKFVRQWQGKMINIHPSLLPLYKG--- 114
P+ L + L ++ +D V+LAG+++++ + V+ + +++NIHP+LLP + G
Sbjct 139 EPSDGLSPSELVDVLRKYGVDFVLLAGYLKLIPVELVQAFPKRILNIHPALLPAFGGKGL 198
Query 115 --MHTHQRVLNTGDVYHGCTVHYVTAELDAGPSLLQGVLKVEQHDTVATLANRIHELEHV 172
+ H+ VL +G Y G T+H+V E D G L Q ++V +DT LA R+ EH
Sbjct 199 YGIKVHKAVLESGARYSGPTIHFVNEEYDTGRILAQSAVRVIANDTPEELAKRVLHEEHK 258
Query 173 IYPQVVEWICTNIIQYQSDQVLL 195
+Y +VV IC I+++ D V L
Sbjct 259 LYVEVVGAICEERIKWREDGVPL 281
Lambda K H a alpha
0.324 0.139 0.418 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1387945
Database: 31885700b0962e39ed22cdd4c7022849.SwissProt.fasta
Posted date: May 9, 2024 7:58 AM
Number of letters in database: 9,032
Number of sequences in database: 11
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
