BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 7c7f8de8d1de6a54b896cd6db5ea3123.SwissProt.fasta
20 sequences; 8,388 total letters
Query= ACIAD2680
Length=424
Score E
Sequences producing significant alignments: (Bits) Value
P96110 Glutamate dehydrogenase [Thermotoga maritima (strain ATCC ... 452 2e-161
P80319 Glutamate dehydrogenase [Pyrococcus furiosus (strain ATCC ... 384 1e-134
P27346 NAD-specific glutamate dehydrogenase [Clostridioides diffi... 384 2e-134
O74024 Glutamate dehydrogenase [Thermococcus profundus] 382 1e-133
Q47950 Glutamate dehydrogenase [Pyrococcus abyssi (strain GE5 / O... 376 2e-131
P0CL72 Glutamate dehydrogenase [Pyrococcus horikoshii] 375 8e-131
P0CL73 Glutamate dehydrogenase [Pyrococcus horikoshii (strain ATC... 375 8e-131
Q56304 Glutamate dehydrogenase [Thermococcus litoralis (strain AT... 372 6e-130
Q47951 Glutamate dehydrogenase [Pyrococcus endeavori] 372 9e-130
P29051 NAD-specific glutamate dehydrogenase A [Halobacterium sali... 365 5e-127
Q6GAW8 NAD-specific glutamate dehydrogenase [Staphylococcus aureu... 363 2e-126
Q6GID0 NAD-specific glutamate dehydrogenase [Staphylococcus aureu... 363 2e-126
Q7A6H8 NAD-specific glutamate dehydrogenase [Staphylococcus aureu... 363 2e-126
Q99VD0 NAD-specific glutamate dehydrogenase [Staphylococcus aureu... 363 2e-126
Q5HHC7 NAD-specific glutamate dehydrogenase [Staphylococcus aureu... 363 2e-126
F2Z610 Glutamate dehydrogenase A2 [Halobacterium salinarum] 362 5e-126
Q9HQE1 Glutamate dehydrogenase A2 [Halobacterium salinarum (strai... 362 5e-126
P50735 Cryptic catabolic NAD-specific glutamate dehydrogenase Gud... 360 4e-125
P54386 NADP-specific glutamate dehydrogenase [Synechocystis sp. (... 358 3e-124
O59650 Glutamate dehydrogenase [Thermococcus kodakarensis (strain... 357 1e-123
>P96110 Glutamate dehydrogenase [Thermotoga maritima (strain ATCC
43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)]
Length=416
Score = 452 bits (1163), Expect = 2e-161
Identities = 230/397 (58%), Positives = 287/397 (72%), Gaps = 4/397 (1%)
Query 27 LEADLIPYINTLKRPKRALIVDVPIVMDDGAIQHFEGYRVQHNLSRGPGKGGIRYHPDVE 86
LE+DL L+RPKR LIV+ P+ MDDG ++ F GYRVQHN++RGP KGGIRYHPDV
Sbjct 23 LESDLA---EVLRRPKRVLIVEFPVRMDDGHVEVFTGYRVQHNVARGPAKGGIRYHPDVT 79
Query 87 LNEVMALSAWMTIKTAVLNLPYGGAKGGIRVDPKKLSARELERLTRRFTSEISPIIGPQN 146
L+EV AL+ WMT KTAV+NLP+GG KGG+RVDPKKLS ELERL+RRF SEI IIGP N
Sbjct 80 LDEVKALAFWMTWKTAVMNLPFGGGKGGVRVDPKKLSRNELERLSRRFFSEIQVIIGPYN 139
Query 147 DIPAPDVGTNADIMGWMMDTYSSIKGHTVTGVVTGKPVHLGGSLGRVRATGRGVFVTGLE 206
DIPAPDV TNAD+M W MDTYS GHTV G+VTGKPV LGGS GR ATGRGV V
Sbjct 140 DIPAPDVNTNADVMAWYMDTYSMNVGHTVLGIVTGKPVELGGSKGREEATGRGVKVCAGL 199
Query 207 VAKKINLSIENSRVAVQGFGNVGSEAAYLFN-KANAKVVCAQDHTGTIFNDDGLDVKSLQ 265
+ + + + VAVQGFGNVG AA L + + +KVV D G I+N +G DV+ L
Sbjct 200 AMDVLGIDPKKATVAVQGFGNVGQFAALLISQELGSKVVAVSDSRGGIYNPEGFDVEELI 259
Query 266 EHVAQTGGVAGFPDSSKIEDAEFWNVEMDILVPAALEGQITAERAQTLKAKLVLEGANGP 325
+ + G V +P +I + E +++DILVPAALEG I A A+ +KAK V+EGANGP
Sbjct 260 RYKKEHGTVVTYPKGERITNEELLELDVDILVPAALEGAIHAGNAERIKAKAVVEGANGP 319
Query 326 TYPDADDVLGQRNIIVVPDVLCNAGGVTVSYFEWVQDMSSYFWTEDEINARLDKLMIQAV 385
T P+AD++L +R I+VVPD+L NAGGVTVSYFEWVQD+ S+FW D++ L+K+M A
Sbjct 320 TTPEADEILSRRGILVVPDILANAGGVTVSYFEWVQDLQSFFWDLDQVRNALEKMMKGAF 379
Query 386 DDVWKKAQEKSCTMRTAAYILACERILKARKERGIFP 422
+DV K ++ + MRTAAYILA +R+ A K+RGI+P
Sbjct 380 NDVMKVKEKYNVDMRTAAYILAIDRVAYATKKRGIYP 416
>P80319 Glutamate dehydrogenase [Pyrococcus furiosus (strain ATCC
43587 / DSM 3638 / JCM 8422 / Vc1)]
Length=420
Score = 384 bits (987), Expect = 1e-134
Identities = 196/411 (48%), Positives = 274/411 (67%), Gaps = 5/411 (1%)
Query 13 WQTYLAQVDRVAPYLEADLIPYINTLKRPKRALIVDVPIVMDDGAIQHFEGYRVQHNLSR 72
++ + Q++R A Y+E + LKRP+R + V +P+ MDDG+++ F G+RVQHN +R
Sbjct 7 YEIVIKQLERAAQYMEISE-EALEFLKRPQRIVEVTIPVEMDDGSVKVFTGFRVQHNWAR 65
Query 73 GPGKGGIRYHPDVELNEVMALSAWMTIKTAVLNLPYGGAKGGIRVDPKKLSARELERLTR 132
GP KGGIR+HP+ L+ V AL+AWMT KTAV++LPYGG KGGI VDPKKLS RE ERL R
Sbjct 66 GPTKGGIRWHPEETLSTVKALAAWMTWKTAVMDLPYGGGKGGIIVDPKKLSDREKERLAR 125
Query 133 RFTSEISPIIGPQNDIPAPDVGTNADIMGWMMDTYSSIKGHTVT--GVVTGKPVHLGGSL 190
+ I +I P DIPAPDV TN IM WMMD Y +I G++TGKP+ +GGSL
Sbjct 126 GYIRAIYDVISPYEDIPAPDVYTNPQIMAWMMDEYETISRRKTPAFGIITGKPLSIGGSL 185
Query 191 GRVRATGRGVFVTGLEVAKKINL-SIENSRVAVQGFGNVGSEAAYLFNKA-NAKVVCAQD 248
GR+ AT RG T E AK + +++ +A+QG+GN G A + ++ KVV D
Sbjct 186 GRIEATARGASYTIREAAKVLGWDTLKGKTIAIQGYGNAGYYLAKIMSEDFGMKVVAVSD 245
Query 249 HTGTIFNDDGLDVKSLQEHVAQTGGVAGFPDSSKIEDAEFWNVEMDILVPAALEGQITAE 308
G I+N DGL+ + + + G V FP ++ I + E +E+D+L PAA+E IT +
Sbjct 246 SKGGIYNPDGLNADEVLKWKNEHGSVKDFPGATNITNEELLELEVDVLAPAAIEEVITKK 305
Query 309 RAQTLKAKLVLEGANGPTYPDADDVLGQRNIIVVPDVLCNAGGVTVSYFEWVQDMSSYFW 368
A +KAK+V E ANGP P+AD++L ++ I+ +PD LCNAGGVTVSYFEWVQ+++ Y+W
Sbjct 306 NADNIKAKIVAEVANGPVTPEADEILFEKGILQIPDFLCNAGGVTVSYFEWVQNITGYYW 365
Query 369 TEDEINARLDKLMIQAVDDVWKKAQEKSCTMRTAAYILACERILKARKERG 419
T +E+ RLDK M +A DV+ A+EK+ MR AAY++A +R+ +A +RG
Sbjct 366 TIEEVRERLDKKMTKAFYDVYNIAKEKNIHMRDAAYVVAVQRVYQAMLDRG 416
>P27346 NAD-specific glutamate dehydrogenase [Clostridioides difficile]
Length=421
Score = 384 bits (986), Expect = 2e-134
Identities = 185/387 (48%), Positives = 263/387 (68%), Gaps = 5/387 (1%)
Query 38 LKRPKRALIVDVPIVMDDGAIQHFEGYRVQHNLSRGPGKGGIRYHPDVELNEVMALSAWM 97
LK P R + V +P+ MDDG+I+ F+G+R QHN + GP KGGIR+H +V +EV ALS WM
Sbjct 33 LKEPMRVIEVSIPVKMDDGSIKTFKGFRSQHNDAVGPTKGGIRFHQNVSRDEVKALSIWM 92
Query 98 TIKTAVLNLPYGGAKGGIRVDPKKLSARELERLTRRFTSEISPIIGPQNDIPAPDVGTNA 157
T K +V +PYGG KGGI VDP LS ELERL+R + I +IG + D+PAPDV TN
Sbjct 93 TFKCSVTGIPYGGGKGGIIVDPSTLSQGELERLSRGYIDGIYKLIGEKVDVPAPDVNTNG 152
Query 158 DIMGWMMDTYSSIKGHTVTGVVTGKPVHLGGSLGRVRATGRGVFVTGLEVAKKINLSIEN 217
IM WM+D Y+ + G + GV+TGKPV GGSLGR ATG GV VT E A K+ + ++
Sbjct 153 QIMSWMVDEYNKLTGQSSIGVITGKPVEFGGSLGRTAATGFGVAVTAREAAAKLGIDMKK 212
Query 218 SRVAVQGFGNVGSEAAYLFNKANAKVV-----CAQDHTGTIFNDDGLDVKSLQEHVAQTG 272
+++AVQG GNVGS K VV C + + I+N++GLD +++ +++ + G
Sbjct 213 AKIAVQGIGNVGSYTVLNCEKLGGTVVAMAEWCKSEGSYAIYNENGLDGQAMLDYMKEHG 272
Query 273 GVAGFPDSSKIEDAEFWNVEMDILVPAALEGQITAERAQTLKAKLVLEGANGPTYPDADD 332
+ FP + +I EFW ++DI++PAALE IT E A+++KAKLV E ANGPT P+AD+
Sbjct 273 NLLNFPGAKRISLEEFWASDVDIVIPAALENSITKEVAESIKAKLVCEAANGPTTPEADE 332
Query 333 VLGQRNIIVVPDVLCNAGGVTVSYFEWVQDMSSYFWTEDEINARLDKLMIQAVDDVWKKA 392
V +R I++ PD+L NAGGVTVSYFEWVQ++ Y+W+E+E+ + + M++A + +WK
Sbjct 333 VFAERGIVLTPDILTNAGGVTVSYFEWVQNLYGYYWSEEEVEQKEEIAMVKAFESIWKIK 392
Query 393 QEKSCTMRTAAYILACERILKARKERG 419
+E + TMR AAY+ + +++ +A K RG
Sbjct 393 EEYNVTMREAAYMHSIKKVAEAMKLRG 419
>O74024 Glutamate dehydrogenase [Thermococcus profundus]
Length=419
Score = 382 bits (980), Expect = 1e-133
Identities = 196/405 (48%), Positives = 269/405 (66%), Gaps = 6/405 (1%)
Query 19 QVDRVAPYLEADLIPYINTLKRPKRALIVDVPIVMDDGAIQHFEGYRVQHNLSRGPGKGG 78
Q++R A Y++ + LK+P R + V VPI MDDG+++ F G+RVQHN +RGP KGG
Sbjct 13 QLERAAQYMDISE-EALEWLKKPMRIVEVSVPIEMDDGSVKVFTGFRVQHNWARGPTKGG 71
Query 79 IRYHPDVELNEVMALSAWMTIKTAVLNLPYGGAKGGIRVDPKKLSARELERLTRRFTSEI 138
IR+HP L+ V AL+ WMT K AV++LPYGG KGGI V+PK+LS RE ERL R + +
Sbjct 72 IRWHPAETLSTVKALATWMTWKVAVVDLPYGGGKGGIIVNPKELSEREQERLARAYIRAV 131
Query 139 SPIIGPQNDIPAPDVGTNADIMGWMMDTYSSI---KGHTVTGVVTGKPVHLGGSLGRVRA 195
+IGP DIPAPDV TN IMGWMMD Y +I KG GV+TGKP+ +GGSLGR A
Sbjct 132 YDVIGPWTDIPAPDVYTNPKIMGWMMDEYETIMRRKGPAF-GVITGKPLSIGGSLGRGTA 190
Query 196 TGRGVFVTGLEVAKKINLSIENSRVAVQGFGNVGSEAAYLFNKA-NAKVVCAQDHTGTIF 254
T +G T E AK + + ++ ++AVQG+GN G A L + VV D G I+
Sbjct 191 TAQGAIFTIREAAKALGIDLKGKKIAVQGYGNAGYYTAKLAKEQLGMTVVAVSDSRGGIY 250
Query 255 NDDGLDVKSLQEHVAQTGGVAGFPDSSKIEDAEFWNVEMDILVPAALEGQITAERAQTLK 314
N DGLD + + + G V FP ++ I + E +E+D+L PAA+E IT + A +K
Sbjct 251 NPDGLDPDEVLKWKREHGSVKDFPGATNITNEELLELEVDVLAPAAIEEVITEKNADNIK 310
Query 315 AKLVLEGANGPTYPDADDVLGQRNIIVVPDVLCNAGGVTVSYFEWVQDMSSYFWTEDEIN 374
AK+V E ANGP P+ADD+L ++ I+ +PD LCNAGGVTVSYFEWVQ+++ Y+WTE+E+
Sbjct 311 AKIVAEVANGPVTPEADDILREKGILQIPDFLCNAGGVTVSYFEWVQNINGYYWTEEEVR 370
Query 375 ARLDKLMIQAVDDVWKKAQEKSCTMRTAAYILACERILKARKERG 419
+LDK M +A +V+ ++K+ MR AAY++A R+ +A K+RG
Sbjct 371 EKLDKKMTKAFWEVYNTHKDKNIHMRDAAYVVAVSRVYQAMKDRG 415
Score = 19.2 bits (38), Expect = 4.6
Identities = 5/15 (33%), Positives = 12/15 (80%), Gaps = 0/15 (0%)
Query 115 IRVDPKKLSARELER 129
+ +DP +++ ++LER
Sbjct 2 VEIDPFEMAVKQLER 16
>Q47950 Glutamate dehydrogenase [Pyrococcus abyssi (strain GE5
/ Orsay)]
Length=420
Score = 376 bits (966), Expect = 2e-131
Identities = 193/405 (48%), Positives = 269/405 (66%), Gaps = 5/405 (1%)
Query 19 QVDRVAPYLEADLIPYINTLKRPKRALIVDVPIVMDDGAIQHFEGYRVQHNLSRGPGKGG 78
Q++R A Y++ + LKRP+R + V +P+ MDDG+++ F G+RVQ+N +RGP KGG
Sbjct 13 QLERAAQYMKISE-EALEFLKRPQRIVEVTIPVEMDDGSVKVFTGFRVQYNWARGPTKGG 71
Query 79 IRYHPDVELNEVMALSAWMTIKTAVLNLPYGGAKGGIRVDPKKLSARELERLTRRFTSEI 138
IR+HP+ L+ V AL+AWMT KTAV++LPYGG KGGI VDPKKLS RE ERL R + I
Sbjct 72 IRWHPEETLSTVKALAAWMTWKTAVMDLPYGGGKGGIIVDPKKLSDREKERLARGYIRAI 131
Query 139 SPIIGPQNDIPAPDVGTNADIMGWMMDTYSSIKGHTVT--GVVTGKPVHLGGSLGRVRAT 196
+I P DIPAPDV TN IM WMMD Y +I G++TGKP+ +GGSLGR AT
Sbjct 132 YDVISPYEDIPAPDVYTNPQIMAWMMDEYETIARRKTPAFGIITGKPLSIGGSLGRNEAT 191
Query 197 GRGVFVTGLEVAKKINLS-IENSRVAVQGFGNVGSEAAYLFNKA-NAKVVCAQDHTGTIF 254
RG T E AK + ++ +A+QG+GN G A + ++ KVV D G I+
Sbjct 192 ARGASYTIREAAKVLGWDDLKGKTIAIQGYGNAGYYLAKIMSEDYGMKVVAVSDSKGGIY 251
Query 255 NDDGLDVKSLQEHVAQTGGVAGFPDSSKIEDAEFWNVEMDILVPAALEGQITAERAQTLK 314
N DGL+ + + + G V FP ++ I + E +E+D+L PAA+E IT + A +K
Sbjct 252 NPDGLNADEVLKWKREHGSVKDFPGATNITNEELLELEVDVLAPAAIEEVITKKNADNIK 311
Query 315 AKLVLEGANGPTYPDADDVLGQRNIIVVPDVLCNAGGVTVSYFEWVQDMSSYFWTEDEIN 374
AK+V E ANGP P+AD++L ++ I+ +PD LCNAGGVTVSYFEWVQ+++ Y+WT +E+
Sbjct 312 AKIVAEVANGPVTPEADEILFEKGILQIPDFLCNAGGVTVSYFEWVQNITGYYWTLEEVR 371
Query 375 ARLDKLMIQAVDDVWKKAQEKSCTMRTAAYILACERILKARKERG 419
+LDK M +A DV+ A+EK+ MR AAY++A +R+ +A +RG
Sbjct 372 EKLDKKMTKAFYDVYNTAKEKNIHMRDAAYVVAVQRVYQAMLDRG 416
>P0CL72 Glutamate dehydrogenase [Pyrococcus horikoshii]
Length=420
Score = 375 bits (962), Expect = 8e-131
Identities = 192/405 (47%), Positives = 269/405 (66%), Gaps = 5/405 (1%)
Query 19 QVDRVAPYLEADLIPYINTLKRPKRALIVDVPIVMDDGAIQHFEGYRVQHNLSRGPGKGG 78
Q++R A +++ + LKRP+R + V +P+ MDDG+++ F G+RVQ+N +RGP KGG
Sbjct 13 QLERAAQHMKISE-EALEFLKRPQRIVEVTIPVEMDDGSVKVFTGFRVQYNWARGPTKGG 71
Query 79 IRYHPDVELNEVMALSAWMTIKTAVLNLPYGGAKGGIRVDPKKLSARELERLTRRFTSEI 138
IR+HP+ L+ V AL+AWMT KTAV++LPYGG KGGI VDPKKLS RE ERL R + +
Sbjct 72 IRWHPEETLSTVKALAAWMTWKTAVMDLPYGGGKGGIIVDPKKLSDREKERLARGYIRAV 131
Query 139 SPIIGPQNDIPAPDVGTNADIMGWMMDTYSSIKGHTVT--GVVTGKPVHLGGSLGRVRAT 196
II P DIPAPDV TN IM WMMD Y +I G++TGKP+ +GGSLGR AT
Sbjct 132 YDIISPYEDIPAPDVYTNPQIMAWMMDEYETIARRKTPAFGIITGKPLSIGGSLGRNEAT 191
Query 197 GRGVFVTGLEVAKKINLS-IENSRVAVQGFGNVGSEAAYLFNKA-NAKVVCAQDHTGTIF 254
RG T E AK + ++ +A+QG+GN G A + ++ KVV D G I+
Sbjct 192 ARGASYTIREAAKVLGWDGLKGKTIAIQGYGNAGYYLAKIMSEDYGMKVVAVSDSKGGIY 251
Query 255 NDDGLDVKSLQEHVAQTGGVAGFPDSSKIEDAEFWNVEMDILVPAALEGQITAERAQTLK 314
N DGL+ + + + G V FP ++ I + E +++D+L PAA+E IT + A +K
Sbjct 252 NPDGLNADEVLKWKREHGSVKDFPGATNISNEELLELDVDVLAPAAIEEVITKKNADNIK 311
Query 315 AKLVLEGANGPTYPDADDVLGQRNIIVVPDVLCNAGGVTVSYFEWVQDMSSYFWTEDEIN 374
AK+V E ANGP P+AD++L ++ I+ +PD LCNAGGVTVSYFEWVQ+++ Y+WT +E+
Sbjct 312 AKIVAEVANGPVTPEADEILFEKGILQIPDFLCNAGGVTVSYFEWVQNITGYYWTLEEVR 371
Query 375 ARLDKLMIQAVDDVWKKAQEKSCTMRTAAYILACERILKARKERG 419
RLDK M +A DV+ A+EK+ MR AAY++A +R+ +A +RG
Sbjct 372 ERLDKKMTKAFYDVYNTAKEKNIHMRDAAYVVAVQRVYQAMLDRG 416
>P0CL73 Glutamate dehydrogenase [Pyrococcus horikoshii (strain
ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)]
Length=420
Score = 375 bits (962), Expect = 8e-131
Identities = 192/405 (47%), Positives = 269/405 (66%), Gaps = 5/405 (1%)
Query 19 QVDRVAPYLEADLIPYINTLKRPKRALIVDVPIVMDDGAIQHFEGYRVQHNLSRGPGKGG 78
Q++R A +++ + LKRP+R + V +P+ MDDG+++ F G+RVQ+N +RGP KGG
Sbjct 13 QLERAAQHMKISE-EALEFLKRPQRIVEVTIPVEMDDGSVKVFTGFRVQYNWARGPTKGG 71
Query 79 IRYHPDVELNEVMALSAWMTIKTAVLNLPYGGAKGGIRVDPKKLSARELERLTRRFTSEI 138
IR+HP+ L+ V AL+AWMT KTAV++LPYGG KGGI VDPKKLS RE ERL R + +
Sbjct 72 IRWHPEETLSTVKALAAWMTWKTAVMDLPYGGGKGGIIVDPKKLSDREKERLARGYIRAV 131
Query 139 SPIIGPQNDIPAPDVGTNADIMGWMMDTYSSIKGHTVT--GVVTGKPVHLGGSLGRVRAT 196
II P DIPAPDV TN IM WMMD Y +I G++TGKP+ +GGSLGR AT
Sbjct 132 YDIISPYEDIPAPDVYTNPQIMAWMMDEYETIARRKTPAFGIITGKPLSIGGSLGRNEAT 191
Query 197 GRGVFVTGLEVAKKINLS-IENSRVAVQGFGNVGSEAAYLFNKA-NAKVVCAQDHTGTIF 254
RG T E AK + ++ +A+QG+GN G A + ++ KVV D G I+
Sbjct 192 ARGASYTIREAAKVLGWDGLKGKTIAIQGYGNAGYYLAKIMSEDYGMKVVAVSDSKGGIY 251
Query 255 NDDGLDVKSLQEHVAQTGGVAGFPDSSKIEDAEFWNVEMDILVPAALEGQITAERAQTLK 314
N DGL+ + + + G V FP ++ I + E +++D+L PAA+E IT + A +K
Sbjct 252 NPDGLNADEVLKWKREHGSVKDFPGATNISNEELLELDVDVLAPAAIEEVITKKNADNIK 311
Query 315 AKLVLEGANGPTYPDADDVLGQRNIIVVPDVLCNAGGVTVSYFEWVQDMSSYFWTEDEIN 374
AK+V E ANGP P+AD++L ++ I+ +PD LCNAGGVTVSYFEWVQ+++ Y+WT +E+
Sbjct 312 AKIVAEVANGPVTPEADEILFEKGILQIPDFLCNAGGVTVSYFEWVQNITGYYWTLEEVR 371
Query 375 ARLDKLMIQAVDDVWKKAQEKSCTMRTAAYILACERILKARKERG 419
RLDK M +A DV+ A+EK+ MR AAY++A +R+ +A +RG
Sbjct 372 ERLDKKMTKAFYDVYNTAKEKNIHMRDAAYVVAVQRVYQAMLDRG 416
>Q56304 Glutamate dehydrogenase [Thermococcus litoralis (strain
ATCC 51850 / DSM 5473 / JCM 8560 / NS-C)]
Length=419
Score = 372 bits (956), Expect = 6e-130
Identities = 187/404 (46%), Positives = 268/404 (66%), Gaps = 4/404 (1%)
Query 19 QVDRVAPYLEADLIPYINTLKRPKRALIVDVPIVMDDGAIQHFEGYRVQHNLSRGPGKGG 78
Q++R A Y++ + LKRP+R + V +P+ MDDG+++ F G+RVQ+N +RGP KGG
Sbjct 13 QLERAAQYMDISE-EALEFLKRPQRIVEVSIPVEMDDGSVKVFTGFRVQYNWARGPTKGG 71
Query 79 IRYHPDVELNEVMALSAWMTIKTAVLNLPYGGAKGGIRVDPKKLSARELERLTRRFTSEI 138
IR+HP+ L+ V AL+AWMT KTAV++LPYGG KGG+ +PK++S RE ERL R + I
Sbjct 72 IRWHPEETLSTVKALAAWMTWKTAVMDLPYGGGKGGVICNPKEMSDREKERLARGYVRAI 131
Query 139 SPIIGPQNDIPAPDVGTNADIMGWMMDTYSSI--KGHTVTGVVTGKPVHLGGSLGRVRAT 196
+I P DIPAPDV TN IM WMMD Y +I + GV+TGKP +GG + R+ AT
Sbjct 132 YDVISPYTDIPAPDVYTNPQIMAWMMDEYETISRRKDPSFGVITGKPPSVGGIVARMDAT 191
Query 197 GRGVFVTGLEVAKKINLSIENSRVAVQGFGNVGSEAAYLFNKA-NAKVVCAQDHTGTIFN 255
RG T E AK + + ++ +A+QG+GN G A + ++ KVV D G I+N
Sbjct 192 ARGASYTVREAAKALGMDLKGKTIAIQGYGNAGYYMAKIMSEEYGMKVVAVSDSKGGIYN 251
Query 256 DDGLDVKSLQEHVAQTGGVAGFPDSSKIEDAEFWNVEMDILVPAALEGQITAERAQTLKA 315
DGL+ + +TG V FP ++ I + E +E+D+L P+A+E IT + A +KA
Sbjct 252 PDGLNADEVLAWKKKTGSVKDFPGATNITNEELLELEVDVLAPSAIEEVITKKNADNIKA 311
Query 316 KLVLEGANGPTYPDADDVLGQRNIIVVPDVLCNAGGVTVSYFEWVQDMSSYFWTEDEINA 375
K+V E ANGPT P+AD++L ++ I+++PD LCNAGGVTVSYFEWVQ+++ +WT +E A
Sbjct 312 KIVAELANGPTTPEADEILYEKGILIIPDFLCNAGGVTVSYFEWVQNITGDYWTVEETRA 371
Query 376 RLDKLMIQAVDDVWKKAQEKSCTMRTAAYILACERILKARKERG 419
+LDK M +A DV+ +EK+ MR AAY++A R+ +A K+RG
Sbjct 372 KLDKKMTKAFWDVYNTHKEKNINMRDAAYVVAVSRVYQAMKDRG 415
>Q47951 Glutamate dehydrogenase [Pyrococcus endeavori]
Length=420
Score = 372 bits (955), Expect = 9e-130
Identities = 191/405 (47%), Positives = 266/405 (66%), Gaps = 5/405 (1%)
Query 19 QVDRVAPYLEADLIPYINTLKRPKRALIVDVPIVMDDGAIQHFEGYRVQHNLSRGPGKGG 78
Q++R A Y++ + LKRP+R + V +P+ MDDG ++ F G+RVQ+N +RGP KGG
Sbjct 13 QLERAAQYMKISE-EALEFLKRPQRIVEVTIPVEMDDGTVKVFTGFRVQYNWARGPTKGG 71
Query 79 IRYHPDVELNEVMALSAWMTIKTAVLNLPYGGAKGGIRVDPKKLSARELERLTRRFTSEI 138
IR+HP+ L+ V AL+AWMT KTAV++LPYGG KGGI VDPKKLS RE ERL R + I
Sbjct 72 IRWHPEETLSTVKALAAWMTWKTAVMDLPYGGGKGGIIVDPKKLSDREKERLARGYIRAI 131
Query 139 SPIIGPQNDIPAPDVGTNADIMGWMMDTYSSIKGHTVT--GVVTGKPVHLGGSLGRVRAT 196
+I P DIPAPDV TN IM WMMD Y +I G++TGKP+ +GGSLGR AT
Sbjct 132 YDVISPYEDIPAPDVYTNPQIMAWMMDEYEAISRRKTPAFGIITGKPLSIGGSLGRNEAT 191
Query 197 GRGVFVTGLEVAKKINLS-IENSRVAVQGFGNVGSEAAYLFNKA-NAKVVCAQDHTGTIF 254
RG T E K + ++ +A+QG+GN G A + ++ KVV D G I+
Sbjct 192 ARGASYTIREARKVLGWGDLKGKTIAIQGYGNAGYYLAKIMSEDYGMKVVAVSDSKGGIY 251
Query 255 NDDGLDVKSLQEHVAQTGGVAGFPDSSKIEDAEFWNVEMDILVPAALEGQITAERAQTLK 314
N DGL+ + + + G V FP ++ I + E +E+D+L PAA+E IT + A +K
Sbjct 252 NPDGLNADEVLKWKQEHGSVKDFPGATNITNEELLELEVDVLAPAAIEEVITKKNADNIK 311
Query 315 AKLVLEGANGPTYPDADDVLGQRNIIVVPDVLCNAGGVTVSYFEWVQDMSSYFWTEDEIN 374
AK+V E ANGP P+AD++L ++ I+ +PD LCNAGGVTVSYFEWVQ+++ Y+WT +E+
Sbjct 312 AKIVAEVANGPVTPEADEILFEKGILQIPDFLCNAGGVTVSYFEWVQNITGYYWTLEEVR 371
Query 375 ARLDKLMIQAVDDVWKKAQEKSCTMRTAAYILACERILKARKERG 419
+LDK M +A DV+ A+EK+ MR A Y++A +R+ +A +RG
Sbjct 372 EKLDKKMTKAFYDVYNTAKEKNIHMRDADYVVAVQRVYQAMLDRG 416
>P29051 NAD-specific glutamate dehydrogenase A [Halobacterium
salinarum]
Length=435
Score = 365 bits (938), Expect = 5e-127
Identities = 190/415 (46%), Positives = 261/415 (63%), Gaps = 2/415 (0%)
Query 8 ENNGAWQTYLAQVDRVAPYLEADLIPYINTLKRPKRALIVDVPIVMDDGAIQHFEGYRVQ 67
E A +T Q+ A YL+ D + LK PK+ V +PI DDG ++ F GYR Q
Sbjct 23 EPESALETARRQLYHAASYLDIDQ-NIVERLKYPKKVHEVTIPIERDDGTVEVFTGYRAQ 81
Query 68 HNLSRGPGKGGIRYHPDVELNEVMALSAWMTIKTAVLNLPYGGAKGGIRVDPKKLSAREL 127
H+ RGP KGG+RYHPDV +E + L WMT K AV++LP+GGAKGG+ V+PK+LS E
Sbjct 82 HDSVRGPYKGGLRYHPDVTRDECVGLGMWMTWKCAVMDLPFGGAKGGVAVNPKELSPEEK 141
Query 128 ERLTRRFTSEISPIIGPQNDIPAPDVGTNADIMGWMMDTYSSIKGHTVTGVVTGKPVHLG 187
ERLTRRFT EI +IGP DIPAPD+GT+ M W+MD YS +G T GVVTGKP +G
Sbjct 142 ERLTRRFTQEIRDVIGPNQDIPAPDMGTDPQTMAWLMDAYSMQEGETTPGVVTGKPPVVG 201
Query 188 GSLGRVRATGRGVFVTGLEVAKKINLSIENSRVAVQGFGNVGSEAAYLFNKANAKVVCAQ 247
GS GR A GR V + V + + ++ + VAVQG+G+VG+ AA L +K A +V
Sbjct 202 GSEGREEAPGRSVAIITQLVCEYYDQPLDETTVAVQGYGSVGANAARLLDKWGATIVAIS 261
Query 248 DHTGTIFNDDGLDVKSLQEHVAQTGGVAGFPDSSKIEDAEFWNVEMDILVPAALEGQITA 307
D G ++ DG+D S+ H + V + D + I + E +++D+L+PAAL IT
Sbjct 262 DVNGAMYEPDGIDTASVPSHDEEPEAVTTYAD-TVISNEELLTLDVDVLIPAALGNVITK 320
Query 308 ERAQTLKAKLVLEGANGPTYPDADDVLGQRNIIVVPDVLCNAGGVTVSYFEWVQDMSSYF 367
E A+ + A LV+EGANGPT AD +L R++ V+PD+L NAGGVTVSYFEW+QD++
Sbjct 321 ENAEAIAADLVVEGANGPTTSTADSILADRDVAVIPDILANAGGVTVSYFEWLQDINRRA 380
Query 368 WTEDEINARLDKLMIQAVDDVWKKAQEKSCTMRTAAYILACERILKARKERGIFP 422
W+ + +N L+ M A V + + + T R AAYI+A RI +A + RG++P
Sbjct 381 WSLERVNDELEAEMQAAWRAVKDEYENRDVTWRDAAYIVALSRIAEAHEARGLWP 435
>Q6GAW8 NAD-specific glutamate dehydrogenase [Staphylococcus aureus
(strain MSSA476)]
Length=414
Score = 363 bits (932), Expect = 2e-126
Identities = 179/382 (47%), Positives = 251/382 (66%), Gaps = 1/382 (0%)
Query 38 LKRPKRALIVDVPIVMDDGAIQHFEGYRVQHNLSRGPGKGGIRYHPDVELNEVMALSAWM 97
+K P R L V +P+ MDDG ++ F GYR QHN + GP KGG+R+HPDV+ EV ALS WM
Sbjct 32 IKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWM 91
Query 98 TIKTAVLNLPYGGAKGGIRVDPKKLSARELERLTRRFTSEISPIIGPQNDIPAPDVGTNA 157
T+K ++NLPYGG KGGI DP+++S E+ERL+R + IS +GP DIPAPDV TN+
Sbjct 92 TLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNS 151
Query 158 DIMGWMMDTYSSIKGHTVTGVVTGKPVHLGGSLGRVRATGRGVFVTGLEVAKKINLSIEN 217
IM WMMD YS++ G +TGKP+ LGGS GR R+T GV + + AK+ N+ IE
Sbjct 152 QIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEG 211
Query 218 SRVAVQGFGNVGSEAAYLFNKANAKVVCAQDHTGTIFNDDGLDVKSLQEHVAQTGGVAGF 277
++V +QGFGN GS A AK+V D G + + +GLD+ L + G V
Sbjct 212 AKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNL 271
Query 278 PDSSKIEDAEFWNVEMDILVPAALEGQITAERAQTLKAKLVLEGANGPTYPDADDVLGQR 337
+ + I + E + ++ DILVPAA+ QIT + A +KA +V+E ANGPT P+A +L +R
Sbjct 272 FEET-ISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTER 330
Query 338 NIIVVPDVLCNAGGVTVSYFEWVQDMSSYFWTEDEINARLDKLMIQAVDDVWKKAQEKSC 397
I++VPDVL +AGGVTVSYFEWVQ+ Y+W+E+E+N +L + + A D +++ +Q +
Sbjct 331 GILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKI 390
Query 398 TMRTAAYILACERILKARKERG 419
MR AAYI+ +R +A + RG
Sbjct 391 DMRLAAYIIGIKRTAEAARYRG 412
>Q6GID0 NAD-specific glutamate dehydrogenase [Staphylococcus aureus
(strain MRSA252)]
Length=414
Score = 363 bits (932), Expect = 2e-126
Identities = 179/382 (47%), Positives = 251/382 (66%), Gaps = 1/382 (0%)
Query 38 LKRPKRALIVDVPIVMDDGAIQHFEGYRVQHNLSRGPGKGGIRYHPDVELNEVMALSAWM 97
+K P R L V +P+ MDDG ++ F GYR QHN + GP KGG+R+HPDV+ EV ALS WM
Sbjct 32 IKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWM 91
Query 98 TIKTAVLNLPYGGAKGGIRVDPKKLSARELERLTRRFTSEISPIIGPQNDIPAPDVGTNA 157
T+K ++NLPYGG KGGI DP+++S E+ERL+R + IS +GP DIPAPDV TN+
Sbjct 92 TLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNS 151
Query 158 DIMGWMMDTYSSIKGHTVTGVVTGKPVHLGGSLGRVRATGRGVFVTGLEVAKKINLSIEN 217
IM WMMD YS++ G +TGKP+ LGGS GR R+T GV + + AK+ N+ IE
Sbjct 152 QIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEG 211
Query 218 SRVAVQGFGNVGSEAAYLFNKANAKVVCAQDHTGTIFNDDGLDVKSLQEHVAQTGGVAGF 277
++V +QGFGN GS A AK+V D G + + +GLD+ L + G V
Sbjct 212 AKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNL 271
Query 278 PDSSKIEDAEFWNVEMDILVPAALEGQITAERAQTLKAKLVLEGANGPTYPDADDVLGQR 337
+ + I + E + ++ DILVPAA+ QIT + A +KA +V+E ANGPT P+A +L +R
Sbjct 272 FEET-ISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTER 330
Query 338 NIIVVPDVLCNAGGVTVSYFEWVQDMSSYFWTEDEINARLDKLMIQAVDDVWKKAQEKSC 397
I++VPDVL +AGGVTVSYFEWVQ+ Y+W+E+E+N +L + + A D +++ +Q +
Sbjct 331 GILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKI 390
Query 398 TMRTAAYILACERILKARKERG 419
MR AAYI+ +R +A + RG
Sbjct 391 DMRLAAYIIGIKRTAEAARYRG 412
>Q7A6H8 NAD-specific glutamate dehydrogenase [Staphylococcus aureus
(strain N315)]
Length=414
Score = 363 bits (932), Expect = 2e-126
Identities = 179/382 (47%), Positives = 251/382 (66%), Gaps = 1/382 (0%)
Query 38 LKRPKRALIVDVPIVMDDGAIQHFEGYRVQHNLSRGPGKGGIRYHPDVELNEVMALSAWM 97
+K P R L V +P+ MDDG ++ F GYR QHN + GP KGG+R+HPDV+ EV ALS WM
Sbjct 32 IKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWM 91
Query 98 TIKTAVLNLPYGGAKGGIRVDPKKLSARELERLTRRFTSEISPIIGPQNDIPAPDVGTNA 157
T+K ++NLPYGG KGGI DP+++S E+ERL+R + IS +GP DIPAPDV TN+
Sbjct 92 TLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNS 151
Query 158 DIMGWMMDTYSSIKGHTVTGVVTGKPVHLGGSLGRVRATGRGVFVTGLEVAKKINLSIEN 217
IM WMMD YS++ G +TGKP+ LGGS GR R+T GV + + AK+ N+ IE
Sbjct 152 QIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEG 211
Query 218 SRVAVQGFGNVGSEAAYLFNKANAKVVCAQDHTGTIFNDDGLDVKSLQEHVAQTGGVAGF 277
++V +QGFGN GS A AK+V D G + + +GLD+ L + G V
Sbjct 212 AKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNL 271
Query 278 PDSSKIEDAEFWNVEMDILVPAALEGQITAERAQTLKAKLVLEGANGPTYPDADDVLGQR 337
+ + I + E + ++ DILVPAA+ QIT + A +KA +V+E ANGPT P+A +L +R
Sbjct 272 FEET-ISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTER 330
Query 338 NIIVVPDVLCNAGGVTVSYFEWVQDMSSYFWTEDEINARLDKLMIQAVDDVWKKAQEKSC 397
I++VPDVL +AGGVTVSYFEWVQ+ Y+W+E+E+N +L + + A D +++ +Q +
Sbjct 331 GILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKI 390
Query 398 TMRTAAYILACERILKARKERG 419
MR AAYI+ +R +A + RG
Sbjct 391 DMRLAAYIIGIKRTAEAARYRG 412
>Q99VD0 NAD-specific glutamate dehydrogenase [Staphylococcus aureus
(strain Mu50 / ATCC 700699)]
Length=414
Score = 363 bits (932), Expect = 2e-126
Identities = 179/382 (47%), Positives = 251/382 (66%), Gaps = 1/382 (0%)
Query 38 LKRPKRALIVDVPIVMDDGAIQHFEGYRVQHNLSRGPGKGGIRYHPDVELNEVMALSAWM 97
+K P R L V +P+ MDDG ++ F GYR QHN + GP KGG+R+HPDV+ EV ALS WM
Sbjct 32 IKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWM 91
Query 98 TIKTAVLNLPYGGAKGGIRVDPKKLSARELERLTRRFTSEISPIIGPQNDIPAPDVGTNA 157
T+K ++NLPYGG KGGI DP+++S E+ERL+R + IS +GP DIPAPDV TN+
Sbjct 92 TLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNS 151
Query 158 DIMGWMMDTYSSIKGHTVTGVVTGKPVHLGGSLGRVRATGRGVFVTGLEVAKKINLSIEN 217
IM WMMD YS++ G +TGKP+ LGGS GR R+T GV + + AK+ N+ IE
Sbjct 152 QIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEG 211
Query 218 SRVAVQGFGNVGSEAAYLFNKANAKVVCAQDHTGTIFNDDGLDVKSLQEHVAQTGGVAGF 277
++V +QGFGN GS A AK+V D G + + +GLD+ L + G V
Sbjct 212 AKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNL 271
Query 278 PDSSKIEDAEFWNVEMDILVPAALEGQITAERAQTLKAKLVLEGANGPTYPDADDVLGQR 337
+ + I + E + ++ DILVPAA+ QIT + A +KA +V+E ANGPT P+A +L +R
Sbjct 272 FEET-ISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTER 330
Query 338 NIIVVPDVLCNAGGVTVSYFEWVQDMSSYFWTEDEINARLDKLMIQAVDDVWKKAQEKSC 397
I++VPDVL +AGGVTVSYFEWVQ+ Y+W+E+E+N +L + + A D +++ +Q +
Sbjct 331 GILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKI 390
Query 398 TMRTAAYILACERILKARKERG 419
MR AAYI+ +R +A + RG
Sbjct 391 DMRLAAYIIGIKRTAEAARYRG 412
>Q5HHC7 NAD-specific glutamate dehydrogenase [Staphylococcus aureus
(strain COL)]
Length=414
Score = 363 bits (932), Expect = 2e-126
Identities = 179/382 (47%), Positives = 251/382 (66%), Gaps = 1/382 (0%)
Query 38 LKRPKRALIVDVPIVMDDGAIQHFEGYRVQHNLSRGPGKGGIRYHPDVELNEVMALSAWM 97
+K P R L V +P+ MDDG ++ F GYR QHN + GP KGG+R+HPDV+ EV ALS WM
Sbjct 32 IKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWM 91
Query 98 TIKTAVLNLPYGGAKGGIRVDPKKLSARELERLTRRFTSEISPIIGPQNDIPAPDVGTNA 157
T+K ++NLPYGG KGGI DP+++S E+ERL+R + IS +GP DIPAPDV TN+
Sbjct 92 TLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNS 151
Query 158 DIMGWMMDTYSSIKGHTVTGVVTGKPVHLGGSLGRVRATGRGVFVTGLEVAKKINLSIEN 217
IM WMMD YS++ G +TGKP+ LGGS GR R+T GV + + AK+ N+ IE
Sbjct 152 QIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEG 211
Query 218 SRVAVQGFGNVGSEAAYLFNKANAKVVCAQDHTGTIFNDDGLDVKSLQEHVAQTGGVAGF 277
++V +QGFGN GS A AK+V D G + + +GLD+ L + G V
Sbjct 212 AKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNL 271
Query 278 PDSSKIEDAEFWNVEMDILVPAALEGQITAERAQTLKAKLVLEGANGPTYPDADDVLGQR 337
+ + I + E + ++ DILVPAA+ QIT + A +KA +V+E ANGPT P+A +L +R
Sbjct 272 FEET-ISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTER 330
Query 338 NIIVVPDVLCNAGGVTVSYFEWVQDMSSYFWTEDEINARLDKLMIQAVDDVWKKAQEKSC 397
I++VPDVL +AGGVTVSYFEWVQ+ Y+W+E+E+N +L + + A D +++ +Q +
Sbjct 331 GILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKI 390
Query 398 TMRTAAYILACERILKARKERG 419
MR AAYI+ +R +A + RG
Sbjct 391 DMRLAAYIIGIKRTAEAARYRG 412
>F2Z610 Glutamate dehydrogenase A2 [Halobacterium salinarum]
Length=416
Score = 362 bits (930), Expect = 5e-126
Identities = 189/414 (46%), Positives = 268/414 (65%), Gaps = 2/414 (0%)
Query 10 NGAWQTYLAQVDRVAPYLEADLIPYINTLKRPKRALIVDVPIVMDDGAIQHFEGYRVQHN 69
+G + LAQ+++ Y++ D Y LK P+R L V +P+ MDDG+++ F+ YR Q +
Sbjct 4 SGPLENMLAQMEQAREYVDIDDGIY-ERLKSPERTLSVSLPVRMDDGSVEVFDAYRCQFD 62
Query 70 LSRGPGKGGIRYHPDVELNEVMALSAWMTIKTAVLNLPYGGAKGGIRVDPKKLSARELER 129
+RGP KGGIRYHP V EV AL+ WMT KTA+++LP+GGAKGGI +PK+LS E+E+
Sbjct 63 SARGPYKGGIRYHPTVSEEEVSALAGWMTWKTALVDLPFGGAKGGIVCNPKELSDNEIEQ 122
Query 130 LTRRFTSEISPIIGPQNDIPAPDVGTNADIMGWMMDTYSSIKGHTVTGVVTGKPVHLGGS 189
LTRR+T I +IGP+ DIPAPD+ T+ M W+MDTYS +G+ V VVTGKP +GG+
Sbjct 123 LTRRYTEGIRRMIGPETDIPAPDMNTDPRTMAWVMDTYSVYQGYAVPEVVTGKPPEIGGT 182
Query 190 LGRVRATGRGVFVTGLEVAKKINLSIENSRVAVQGFGNVGSEAAYLFNKANAKVVCAQDH 249
GRV ATGRGV + E + + I+++ VA+QGFGNVGS A L ++ A +V D
Sbjct 183 DGRVEATGRGVSIITEETFEYFDTDIQDADVAIQGFGNVGSVTADLLSERGANIVAVSDV 242
Query 250 TGTIFNDDGLDVKSLQEHVAQTGGVAGFPDSSKIEDAEFWNVEMDILVPAALEGQITAER 309
TG I + GLD+ +Q + GG D+ I + + +++D L+PAA+E IT +
Sbjct 243 TGAIHDPTGLDIADVQAYADANGGRLEGYDAEPISNDDLLTLDVDALIPAAIEDVITVDV 302
Query 310 AQTLKAKLVLEGANGPTYPDADDVLGQRNIIVVPDVLCNAGGVTVSYFEWVQDMSSYFWT 369
A+ L A +++E ANGPT DA VL R + VVPD+L NAGGV VSY EWVQ+ Y W
Sbjct 303 AERLAADVIVEAANGPTTFDAAQVLSDRGVPVVPDILANAGGVIVSYLEWVQNSQQYSWD 362
Query 370 EDEINARLDKLMIQAVDDVWKKAQEKSC-TMRTAAYILACERILKARKERGIFP 422
+E+N L + + A D++ ++++ T+RTAAY +A ER A + RG+FP
Sbjct 363 VEEVNRDLRQRLTGAFDEMLVAYEDRNIPTLRTAAYTIALERSADAHEFRGLFP 416
>Q9HQE1 Glutamate dehydrogenase A2 [Halobacterium salinarum (strain
ATCC 700922 / JCM 11081 / NRC-1)]
Length=416
Score = 362 bits (930), Expect = 5e-126
Identities = 189/414 (46%), Positives = 268/414 (65%), Gaps = 2/414 (0%)
Query 10 NGAWQTYLAQVDRVAPYLEADLIPYINTLKRPKRALIVDVPIVMDDGAIQHFEGYRVQHN 69
+G + LAQ+++ Y++ D Y LK P+R L V +P+ MDDG+++ F+ YR Q +
Sbjct 4 SGPLENMLAQMEQAREYVDIDDGIY-ERLKSPERTLSVSLPVRMDDGSVEVFDAYRCQFD 62
Query 70 LSRGPGKGGIRYHPDVELNEVMALSAWMTIKTAVLNLPYGGAKGGIRVDPKKLSARELER 129
+RGP KGGIRYHP V EV AL+ WMT KTA+++LP+GGAKGGI +PK+LS E+E+
Sbjct 63 SARGPYKGGIRYHPTVSEEEVSALAGWMTWKTALVDLPFGGAKGGIVCNPKELSDNEIEQ 122
Query 130 LTRRFTSEISPIIGPQNDIPAPDVGTNADIMGWMMDTYSSIKGHTVTGVVTGKPVHLGGS 189
LTRR+T I +IGP+ DIPAPD+ T+ M W+MDTYS +G+ V VVTGKP +GG+
Sbjct 123 LTRRYTEGIRRMIGPETDIPAPDMNTDPRTMAWVMDTYSVYQGYAVPEVVTGKPPEIGGT 182
Query 190 LGRVRATGRGVFVTGLEVAKKINLSIENSRVAVQGFGNVGSEAAYLFNKANAKVVCAQDH 249
GRV ATGRGV + E + + I+++ VA+QGFGNVGS A L ++ A +V D
Sbjct 183 DGRVEATGRGVSIITEETFEYFDTDIQDADVAIQGFGNVGSVTADLLSERGANIVAVSDV 242
Query 250 TGTIFNDDGLDVKSLQEHVAQTGGVAGFPDSSKIEDAEFWNVEMDILVPAALEGQITAER 309
TG I + GLD+ +Q + GG D+ I + + +++D L+PAA+E IT +
Sbjct 243 TGAIHDPTGLDIADVQAYADANGGRLEGYDAEPISNDDLLTLDVDALIPAAIEDVITVDV 302
Query 310 AQTLKAKLVLEGANGPTYPDADDVLGQRNIIVVPDVLCNAGGVTVSYFEWVQDMSSYFWT 369
A+ L A +++E ANGPT DA VL R + VVPD+L NAGGV VSY EWVQ+ Y W
Sbjct 303 AERLAADVIVEAANGPTTFDAAQVLSDRGVPVVPDILANAGGVIVSYLEWVQNSQQYSWD 362
Query 370 EDEINARLDKLMIQAVDDVWKKAQEKSC-TMRTAAYILACERILKARKERGIFP 422
+E+N L + + A D++ ++++ T+RTAAY +A ER A + RG+FP
Sbjct 363 VEEVNRDLRQRLTGAFDEMLVAYEDRNIPTLRTAAYTIALERSADAHEFRGLFP 416
>P50735 Cryptic catabolic NAD-specific glutamate dehydrogenase
GudB [Bacillus subtilis (strain 168)]
Length=427
Score = 360 bits (925), Expect = 4e-125
Identities = 184/386 (48%), Positives = 257/386 (67%), Gaps = 6/386 (2%)
Query 38 LKRPKRALIVDVPIVMDDGAIQHFEGYRVQHNLSRGPGKGGIRYHPDV---ELNEVMALS 94
LK P R L V +P+ MDDG+++ F GYR QHN S GP KGGIR+HP+V E+ V ALS
Sbjct 42 LKEPMRLLTVKIPVRMDDGSVKIFTGYRAQHNDSVGPTKGGIRFHPNVTEKEVKAVKALS 101
Query 95 AWMTIKTAVLNLPYGGAKGGIRVDPKKLSARELERLTRRFTSEISPIIGPQNDIPAPDVG 154
WM++K +++LPYGG KGGI DP+ +S RELERL+R + IS I+GP D+PAPDV
Sbjct 102 IWMSLKCGIIDLPYGGGKGGIVCDPRDMSFRELERLSRGYVRAISQIVGPTKDVPAPDVF 161
Query 155 TNADIMGWMMDTYSSIKGHTVTGVVTGKPVHLGGSLGRVRATGRGVFVTGLEVAKKINLS 214
TN+ IM WMMD YS I G +TGKP+ LGGS GR AT +GV + E AKK +
Sbjct 162 TNSQIMAWMMDEYSRIDEFNSPGFITGKPLVLGGSHGRESATAKGVTICIKEAAKKRGID 221
Query 215 IENSRVAVQGFGNVGSEAAYLFNKANAKVVCAQDHTGTIFNDDGLDVKSLQEHVAQTGGV 274
I+ +RV VQGFGN GS A + A AKVV D G +++ +GLD+ L + G V
Sbjct 222 IKGARVVVQGFGNAGSYLAKFMHDAGAKVVGISDAYGGLYDPEGLDIDYLLDRRDSFGTV 281
Query 275 AG-FPDSSKIEDAEFWNVEMDILVPAALEGQITAERAQTLKAKLVLEGANGPTYPDADDV 333
F D+ I + E ++ DILVPAA+E QIT E A ++AK+V+E ANGPT + +
Sbjct 282 TKLFNDT--ITNQELLELDCDILVPAAIENQITEENAHNIRAKIVVEAANGPTTLEGTKI 339
Query 334 LGQRNIIVVPDVLCNAGGVTVSYFEWVQDMSSYFWTEDEINARLDKLMIQAVDDVWKKAQ 393
L R+I++VPDVL +AGGVTVSYFEWVQ+ ++W+E+E+ +L+K+M+++ +++++ A
Sbjct 340 LSDRDILLVPDVLASAGGVTVSYFEWVQNNQGFYWSEEEVEEKLEKMMVKSFNNIYEMAN 399
Query 394 EKSCTMRTAAYILACERILKARKERG 419
+ MR AAY++ ++ +A + RG
Sbjct 400 NRRIDMRLAAYMVGVRKMAEASRFRG 425
>P54386 NADP-specific glutamate dehydrogenase [Synechocystis sp.
(strain PCC 6803 / Kazusa)]
Length=428
Score = 358 bits (919), Expect = 3e-124
Identities = 185/391 (47%), Positives = 252/391 (64%), Gaps = 9/391 (2%)
Query 38 LKRPKRALIVDVPIVMDDGAIQHFEGYRVQHNLSRGPGKGGIRYHPDVELNEVMALSAWM 97
LK PK +L V +P+ MDDG+++ F GYRV+++ +RGPGKGG+RYHP+V ++EV +L+ WM
Sbjct 30 LKYPKTSLSVSIPVRMDDGSLKIFPGYRVRYDDTRGPGKGGVRYHPNVTMDEVQSLAFWM 89
Query 98 TIKTAVLNLPYGGAKGGIRVDPKKLSARELERLTRRFTSEISPIIGPQNDIPAPDVGTNA 157
T K A+LNLP+GGAKGGI ++PK+LS ELERL+R + I+ IGP DI APDV TN
Sbjct 90 TFKCALLNLPFGGAKGGITLNPKELSRAELERLSRGYIEAIADFIGPDIDILAPDVYTNE 149
Query 158 DIMGWMMDTYSSIKGHTVTGVVTGKPVHLGGSLGRVRATGRGVFVTGLEVAKKINLSIEN 217
+MGWMMD YS I+ VVTGKPV +GGS GR ATG G F + K + EN
Sbjct 150 MMMGWMMDQYSIIRRKISPAVVTGKPVTMGGSQGRNTATGTGAFYIMQGMLPKFDQYPEN 209
Query 218 SRVAVQGFGNVGSEAAYLFNKANAKVVCAQDHTGTIFNDDGLDVKSL----QEHVAQTG- 272
+ VAVQGFGN G A + KVV D G I+N+ G+D+ ++ Q H G
Sbjct 210 TTVAVQGFGNAGMVVAECLYQDGYKVVAISDSQGGIYNEQGIDIPAVIDYKQRHRTLAGM 269
Query 273 ----GVAGFPDSSKIEDAEFWNVEMDILVPAALEGQITAERAQTLKAKLVLEGANGPTYP 328
+ ++ +I +AE +++D+L+PAALE QIT + A ++A+ + E ANGPT
Sbjct 270 YCDQAICDLGENQQISNAELLALDVDVLIPAALENQITRDNADQVRARYIFEVANGPTTT 329
Query 329 DADDVLGQRNIIVVPDVLCNAGGVTVSYFEWVQDMSSYFWTEDEINARLDKLMIQAVDDV 388
ADD+L + I V PD+L NAGGVTVSYFEWVQ+ S +W+ E+N RL + M++ + V
Sbjct 330 AADDILASKGIYVFPDILVNAGGVTVSYFEWVQNRSGLYWSAKEVNDRLKEKMVEEAEHV 389
Query 389 WKKAQEKSCTMRTAAYILACERILKARKERG 419
W QE +RTAAYI A R+ +A +G
Sbjct 390 WNITQELDVNVRTAAYIHALNRLSEAMDAKG 420
>O59650 Glutamate dehydrogenase [Thermococcus kodakarensis (strain
ATCC BAA-918 / JCM 12380 / KOD1)]
Length=421
Score = 357 bits (915), Expect = 1e-123
Identities = 192/410 (47%), Positives = 260/410 (63%), Gaps = 14/410 (3%)
Query 19 QVDRVAPYLEADLIPYINTLKRPKRALIVDVPIVMDDGAIQHFEGYRVQHNLSRGPGKGG 78
Q++R A +++ + LKRP R + V VP+ MDDG+++ F G+RVQHN +RGP KGG
Sbjct 13 QLERAAQFMDISE-EALEWLKRPMRIVEVSVPVEMDDGSVKVFTGFRVQHNWARGPTKGG 71
Query 79 IRYHPDVELNEVMALSAWMTIKTAVLNLPYGGAKGGIRVDPKKLSARELERLTRRFTSEI 138
IR+HP L+ V AL+ WMT K AV++LPYGG KGGI VDPKKLS RE ERL R + +
Sbjct 72 IRWHPAETLSTVKALATWMTWKVAVVDLPYGGGKGGIIVDPKKLSEREQERLARSYIRAV 131
Query 139 SPIIGPQNDIPAPDVGTNADIMGWMMDTYSSI--KGHTVTGVVTGKPVHLGGSLGRVRAT 196
+IGP DIPAPDV TN IM WMMD Y +I + GV+TGKP +GG + R+ AT
Sbjct 132 YDVIGPWTDIPAPDVYTNPKIMAWMMDEYETIMRRKGPAFGVITGKPPGVGGIVARMDAT 191
Query 197 GRGVFVTGLEVAKKINL-SIENSRVAVQGFGNVGSEAAYLFNKA-NAKVVCAQDHTGTIF 254
RG T E AK + ++ +A+QG+GN G + ++ KVV D G I+
Sbjct 192 ARGAAFTIREAAKALGWDDLKGKTIAIQGYGNAGYYLHKIMSEEFGMKVVAVSDSKGGIY 251
Query 255 NDDGLD-----VKSLQEHVAQTGGVAGFPDSSKIEDAEFWNVEMDILVPAALEGQITAER 309
N DGL +K +EH G V P + I + E +E+DIL P+A+EG IT E
Sbjct 252 NPDGLPPADEVLKWKKEH----GSVKDMPGTQNITNEELLELEVDILAPSAIEGVITKEN 307
Query 310 AQTLKAKLVLEGANGPTYPDADDVLGQRNIIVVPDVLCNAGGVTVSYFEWVQDMSSYFWT 369
A +KAK+V E ANGP P+AD++L ++ I+ +PD LCNAGGVTVSYFEWVQ+++ ++WT
Sbjct 308 ADNVKAKIVAEVANGPVTPEADEILHEKGILQIPDFLCNAGGVTVSYFEWVQNINGFYWT 367
Query 370 EDEINARLDKLMIQAVDDVWKKAQEKSCTMRTAAYILACERILKARKERG 419
+E RLD M +A DV+ +EK+ MR AAY++A R+ +A K RG
Sbjct 368 VEETRKRLDDKMTKAFWDVFNTHKEKNIHMRDAAYVVAVSRVYEAMKHRG 417
Score = 18.9 bits (37), Expect = 6.0
Identities = 5/15 (33%), Positives = 12/15 (80%), Gaps = 0/15 (0%)
Query 115 IRVDPKKLSARELER 129
+ +DP +++ ++LER
Sbjct 2 VEIDPFEMAVQQLER 16
Lambda K H a alpha
0.319 0.136 0.407 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 2733456
Database: 7c7f8de8d1de6a54b896cd6db5ea3123.SwissProt.fasta
Posted date: May 17, 2024 5:07 AM
Number of letters in database: 8,388
Number of sequences in database: 20
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
