BLASTP 2.12.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: 54a14e504c89a6b07850891a4e846d1a.SwissProt.fasta
           12 sequences; 6,628 total letters



Query= ACIAD2770

Length=540
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

P40871 2,3-dihydroxybenzoate-AMP ligase [Bacillus subtilis (strai...  404     5e-139
O07899 Vibriobactin-specific 2,3-dihydroxybenzoate-AMP ligase [Vi...  368     7e-125
A0A0H2ZF83 Pyochelin synthase PchD [Pseudomonas aeruginosa (strai...  351     2e-118
Q9HWG3 Pyochelin synthase PchD [Pseudomonas aeruginosa (strain AT...  350     9e-118
Q8XBV3 Enterobactin synthase component E [Escherichia coli O157:H7]   349     1e-117
P10378 Enterobactin synthase component E [Escherichia coli (strai...  349     1e-117
Q7X279 Salicylyl-CoA synthase / salicylate adenylyltransferase [S...  321     2e-106
Q1IAK8 Pseudomonine synthase PmsE [Pseudomonas entomophila (strai...  320     2e-105
Q84HC5 2-hydroxy-7-methoxy-5-methyl-1-naphthoate--CoA ligase [Str...  311     1e-102
P71716 Salicyl-AMP ligase / salicyl-S-ArCP synthetase [Mycobacter...  309     9e-102
P80436 Triostin synthetase I [Streptomyces triostinicus]              302     1e-99 
P38135 Medium-chain fatty-acid--CoA ligase [Escherichia coli (str...  176     1e-51 


>P40871 2,3-dihydroxybenzoate-AMP ligase [Bacillus subtilis (strain 
168)]
Length=539

 Score = 404 bits (1038),  Expect = 5e-139
 Identities = 227/535 (42%), Positives = 313/535 (59%), Gaps = 17/535 (3%)

Query  9    QGYVPFPESRAKQYRAEGCWKSNTHFQMLADSVSRFGDCIAAIQDQKQLTYKQLYDYAIR  68
            +G+ P+P+  A+ YR  GCW   T   +L D  +++GD IA        +Y++L   A R
Sbjct  3    KGFTPWPDELAETYRKNGCWAGETFGDLLRDRAAKYGDRIAITCGNTHWSYRELDTRADR  62

Query  69   YGAYLKHKGIRETDFVLLQSPNVIEVFIVIFGLYAIGARPVFCLHGHGAYEIENIARQSR  128
              A  +  GI++ D V++Q PN+ E F VIF L+ +GA PVF L  H + EI      + 
Sbjct  63   LAAGFQKLGIQQMDRVVVQLPNIKEFFEVIFALFRLGALPVFALPSHRSSEITYFCEFAE  122

Query  129  AVGFIKLCGTANEITAVDVCEEFSVPNF--QLWFRETILSQETIAGSLPQ---LKHLNLD  183
            A  +I            D    F   +   Q+  +   L    +AG   +   L+ L+ +
Sbjct  123  AAAYI----------IPDAYSGFDYRSLARQVQSKLPTLKNIIVAGEAEEFLPLEDLHAE  172

Query  184  TNIQALSSSEDIAFLQLSGGTTGLPKLIPRTHADYIYSIEKSVEVAGLNPQTKQLVVLPV  243
                    S D+AFLQLSGG+TGL KLIPRTH DYIYS+++SVEV  L+  T  L  LP+
Sbjct  173  PVKLPEVKSSDVAFLQLSGGSTGLSKLIPRTHDDYIYSLKRSVEVCWLDHSTVYLAALPM  232

Query  244  MHNFCMSSPGFLGVFYAGGTVVLSQLTQPRVCFELIQKYKIEQVSLVPAIATLWLNAESL  303
             HN+ +SSPG LGV YAGG VVLS    P   F LI++ K+   +LVP +A +W++A S 
Sbjct  233  AHNYPLSSPGVLGVLYAGGRVVLSPSPSPDDAFPLIEREKVTITALVPPLAMVWMDAASS  292

Query  304  KDYDLSSLKVIQVGGAKLLPSLAEQIIDQFQVKLQQVYGMAEGLVNFTHLDDTNAVTIQT  363
            +  DLSSL+V+QVGGAK     A ++   F   LQQV+GMAEGLVN+T LDD   + + T
Sbjct  293  RRDDLSSLQVLQVGGAKFSAEAARRVKAVFGCTLQQVFGMAEGLVNYTRLDDPEEIIVNT  352

Query  364  QGKKLSHLDEIRITDHHGQALPINAIGHIQTRGPYTINGYYNLHEINRRSFTDDGFYKTG  423
            QGK +S  DE+R+ D H + +     GH+ TRGPYTI GYY   E N  SFT+DGFY+TG
Sbjct  353  QGKPMSPYDEMRVWDDHDRDVKPGETGHLLTRGPYTIRGYYKAEEHNAASFTEDGFYRTG  412

Query  424  DIGYLDDDLNIVVTGREKEQINRSGEKVTPSEIEEFILQYPTVKDVCVIGVSDEHLGERI  483
            DI  L  D  IVV GR K+QINR GEKV   E+E  +L +P V D  ++ + D+ LGER 
Sbjct  413  DIVRLTRDGYIVVEGRAKDQINRGGEKVAAEEVENHLLAHPAVHDAAMVSMPDQFLGERS  472

Query  484  KAIIIPKHEDHEISLKNIRKFLTGKNIAHFKIPDEIDVVADFKYTHVGKVNRQKL  538
               IIP+ E  + +   ++ FL  + +A +KIPD ++ V  F  T VGKV+++ L
Sbjct  473  CVFIIPRDEAPKAA--ELKAFLRERGLAAYKIPDRVEFVESFPQTGVGKVSKKAL  525


>O07899 Vibriobactin-specific 2,3-dihydroxybenzoate-AMP ligase 
[Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba 
N16961)]
Length=543

 Score = 368 bits (944),  Expect = 7e-125
 Identities = 208/533 (39%), Positives = 301/533 (56%), Gaps = 12/533 (2%)

Query  11   YVPFPESRAKQYRAEGCWKSNTHFQMLADSVSRFGDCIAAIQDQKQLTYKQLYDYAIRYG  70
            + P+PE+ A QYR  G W+  T    L  S  R  + +A + D +Q  Y+ + +   +  
Sbjct  5    FTPWPEALAAQYRQLGYWQDKTLLDYLQQSAERTPNALALVGDNQQWRYQAMLERIEQLA  64

Query  71   AYLKHKGIRETDFVLLQSPNVIEVFIVIFGLYAIGARPVFCLHGHGAYEIENIARQSRAV  130
            A     G+   D V+LQ  NV E ++  F L   G RP+  L  H   EI    + S+A 
Sbjct  65   AGFTELGLGCGDNVVLQLGNVAEFYLCFFALLRQGIRPILALPAHRLAEIRYFCQHSQAK  124

Query  131  GFIKLCGTANEITAVDVCEEF--SVPNFQLWFRETILSQETIAGSLP---QLKHLNLDTN  185
             ++ + G         + +E     P  Q     T++ +     + P   +L      ++
Sbjct  125  AYL-IDGAQRPFDYQALAQELLACCPTLQ-----TVIVRGQTRVTDPKFIELASCYSASS  178

Query  186  IQALSSSEDIAFLQLSGGTTGLPKLIPRTHADYIYSIEKSVEVAGLNPQTKQLVVLPVMH  245
             QA +    IAF QLSGGTTG PKLIPRTH DY YS+  SVE+   +  T+ L VLP  H
Sbjct  179  CQANADPNQIAFFQLSGGTTGTPKLIPRTHNDYAYSVTASVEICRFDQHTRYLCVLPAAH  238

Query  246  NFCMSSPGFLGVFYAGGTVVLSQLTQPRVCFELIQKYKIEQVSLVPAIATLWLNAESLKD  305
            NF +SSPG LGVF+AGG VVLSQ   P+  F+LI+++KI   +LVP +A LW++      
Sbjct  239  NFPLSSPGALGVFWAGGCVVLSQDASPQHAFKLIEQHKITVTALVPPLALLWMDHAEKST  298

Query  306  YDLSSLKVIQVGGAKLLPSLAEQIIDQFQVKLQQVYGMAEGLVNFTHLDDTNAVTIQTQG  365
            YDLSSL  +QVGGAK   + A ++      +LQQV+GMAEGLVN+T LDD+  +   TQG
Sbjct  299  YDLSSLHFVQVGGAKFSEAAARRLPKALGCQLQQVFGMAEGLVNYTRLDDSAELIATTQG  358

Query  366  KKLSHLDEIRITDHHGQALPINAIGHIQTRGPYTINGYYNLHEINRRSFTDDGFYKTGDI  425
            + +S  D++ + D  GQ +     G++ T+GPYTI GYY   + N+R+F   GFY TGD 
Sbjct  359  RPISAHDQLLVVDEQGQPVASGEEGYLLTQGPYTIRGYYRADQHNQRAFNAQGFYITGDK  418

Query  426  GYLDDDLNIVVTGREKEQINRSGEKVTPSEIEEFILQYPTVKDVCVIGVSDEHLGERIKA  485
              L  +  ++VTGR K+QINR GEK+   E+E  +L +P V D  +I +SDE+LGER  A
Sbjct  419  VKLSSEGYVIVTGRAKDQINRGGEKIAAEEVENQLLHHPAVHDAALIAISDEYLGERSCA  478

Query  486  IIIPKHEDHEISLKNIRKFLTGKNIAHFKIPDEIDVVADFKYTHVGKVNRQKL  538
            +I+ K E   ++   +++FL    +A +KIPD+I  +     T VGK+++  L
Sbjct  479  VIVLKPE-QSVNTIQLKRFLHQAGLADYKIPDQIQFIDQLPKTSVGKIDKNAL  530


>A0A0H2ZF83 Pyochelin synthase PchD [Pseudomonas aeruginosa (strain 
UCBPP-PA14)]
Length=547

 Score = 351 bits (901),  Expect = 2e-118
 Identities = 200/533 (38%), Positives = 290/533 (54%), Gaps = 22/533 (4%)

Query  14   FPESRAKQYRAEGCWKSNTHFQMLADSVSRFGDCIAAIQDQKQLTYKQLYDYAIRYGAYL  73
            +P +  ++Y   G W+     + LA S +R    IA   D ++L+Y  L     R  A L
Sbjct  17   WPAAFVRRYLDAGHWQDQNFAEALAASAARHPRRIALCDDDQRLSYADLLQRCRRLAAGL  76

Query  74   KHKGIRETDFVLLQSPNVIEVFIVIFGLYAIGARPVFCLHGHGAYEIENIARQSRAVGFI  133
            +  G+   D V+L  PN I      F L+ +G RPV  L  H  +EI    R + A  +I
Sbjct  77   RQAGLAHGDTVVLHLPNGIAFVETCFALFQLGVRPVLALPAHRQHEISGFCRFAEAKAYI  136

Query  134  ---KLCG-----TANEITAVDVCEEFSVPNFQLWFRETILSQETIAGSLPQLKHLNLDTN  185
               ++ G      A E+ A   C            R  ++  E  A           D  
Sbjct  137  GAERIDGFDPRPMARELLASGAC------------RMALIHGEAEAPLQALAPLYQADAL  184

Query  186  IQALSSSEDIAFLQLSGGTTGLPKLIPRTHADYIYSIEKSVEVAGLNPQTKQLVVLPVMH  245
                + +EDIA  QLSGGTTG PKLIPR H +Y+Y++  S EV G +  T  L  LP+ H
Sbjct  185  EDCAARAEDIACFQLSGGTTGTPKLIPRRHREYLYNVRASAEVCGFDEHTVYLTGLPMAH  244

Query  246  NFCMSSPGFLGVFYAGGTVVLSQLTQPRVCFELIQKYKIEQVSLVPAIATLWLNAESLKD  305
            NF +  PG +G   AGG VV+SQ   P  CF LI + ++   +LVP +A LWL+A+  + 
Sbjct  245  NFTLCCPGVIGTLLAGGRVVVSQRADPEHCFALIARERVTHTALVPPLAMLWLDAQESRR  304

Query  306  YDLSSLKVIQVGGAKLLPSLAEQIIDQFQVKLQQVYGMAEGLVNFTHLDDTNAVTIQTQG  365
             DLSSL+++QVGG++L  S A+++      +LQQV GMAEGL+ +T LDD     + TQG
Sbjct  305  ADLSSLRLLQVGGSRLGSSAAQRVEPVLGCQLQQVLGMAEGLICYTRLDDPPERVLHTQG  364

Query  366  KKLSHLDEIRITDHHGQALPINAIGHIQTRGPYTINGYYNLHEINRRSFTDDGFYKTGDI  425
            + LS  DE+R+ D  G+ +    +G +  RGPYTI GYY L E N ++F+ DGFY+TGD 
Sbjct  365  RPLSPDDEVRVVDAEGREVGPGEVGELTVRGPYTIRGYYRLPEHNAKAFSADGFYRTGDR  424

Query  426  GYLDDDLNIVVTGREKEQINRSGEKVTPSEIEEFILQYPTVKDVCVIGVSDEHLGERIKA  485
               D D  +VV GR+K+QINR GEK+   E+E  ++ +P V D  V+ + D  LGER  A
Sbjct  425  VSRDKDGYLVVEGRDKDQINRGGEKIAAEEVENLLIAHPQVHDATVVAMPDSLLGERTCA  484

Query  486  IIIPKHEDHEISLKNIRKFLTGKNIAHFKIPDEIDVVADFKYTHVGKVNRQKL  538
             +IP+      S   ++++L    +A FK+PD I++V  F  T +GK++++ L
Sbjct  485  FVIPRQP--APSALKLKQYLHACGLAAFKVPDRIELVPAFPQTGIGKISKKDL  535


 Score = 23.9 bits (50),  Expect = 0.18
 Identities = 17/71 (24%), Positives = 32/71 (45%), Gaps = 12/71 (17%)

Query  9    QGYVPFPESRAKQYRAEGCWKSNTHFQ-----------MLADSVSRFGDCIAAIQDQKQL  57
            +GY   PE  AK + A+G +++                   D ++R G+ IAA + +  L
Sbjct  400  RGYYRLPEHNAKAFSADGFYRTGDRVSRDKDGYLVVEGRDKDQINRGGEKIAAEEVENLL  459

Query  58   -TYKQLYDYAI  67
              + Q++D  +
Sbjct  460  IAHPQVHDATV  470


>Q9HWG3 Pyochelin synthase PchD [Pseudomonas aeruginosa (strain 
ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 
/ 1C / PRS 101 / PAO1)]
Length=547

 Score = 350 bits (897),  Expect = 9e-118
 Identities = 199/533 (37%), Positives = 290/533 (54%), Gaps = 22/533 (4%)

Query  14   FPESRAKQYRAEGCWKSNTHFQMLADSVSRFGDCIAAIQDQKQLTYKQLYDYAIRYGAYL  73
            +P +  ++Y   G W+  +  + LA S +R    IA   D ++L+Y  L     R  A L
Sbjct  17   WPAAFVRRYLDAGHWQDQSFAEALATSAARHPRRIALCDDDQRLSYADLLQRCRRLAAGL  76

Query  74   KHKGIRETDFVLLQSPNVIEVFIVIFGLYAIGARPVFCLHGHGAYEIENIARQSRAVGFI  133
            +  G+   D V+L  PN I      F L+ +G RPV  L  H  +EI    R + A  +I
Sbjct  77   RQAGLAHGDTVVLHLPNGIAFVETCFALFQLGVRPVLALPAHRQHEISGFCRFAEAKAYI  136

Query  134  ---KLCG-----TANEITAVDVCEEFSVPNFQLWFRETILSQETIAGSLPQLKHLNLDTN  185
               ++ G      A E+ A   C            R  ++  E  A           D  
Sbjct  137  GAERIDGFDPRPMARELLASGAC------------RMALIHGEAEAPLQALAPLYQADAL  184

Query  186  IQALSSSEDIAFLQLSGGTTGLPKLIPRTHADYIYSIEKSVEVAGLNPQTKQLVVLPVMH  245
                + +EDIA  QLSGGTTG PKLIPR H +Y+Y++  S EV G +  T  L  LP+ H
Sbjct  185  EDCAARAEDIACFQLSGGTTGTPKLIPRRHREYLYNVRASAEVCGFDEHTVYLTGLPMAH  244

Query  246  NFCMSSPGFLGVFYAGGTVVLSQLTQPRVCFELIQKYKIEQVSLVPAIATLWLNAESLKD  305
            NF +  PG +G   A G VV+SQ   P  CF LI + ++   +LVP +A LWL+A+  + 
Sbjct  245  NFTLCCPGVIGTLLASGRVVVSQRADPEHCFALIARERVTHTALVPPLAMLWLDAQESRR  304

Query  306  YDLSSLKVIQVGGAKLLPSLAEQIIDQFQVKLQQVYGMAEGLVNFTHLDDTNAVTIQTQG  365
             DLSSL+++QVGG++L  S A+++      +LQQV GMAEGL+ +T LDD     + TQG
Sbjct  305  ADLSSLRLLQVGGSRLGSSAAQRVEPVLGCQLQQVLGMAEGLICYTRLDDPPERVLHTQG  364

Query  366  KKLSHLDEIRITDHHGQALPINAIGHIQTRGPYTINGYYNLHEINRRSFTDDGFYKTGDI  425
            + LS  DE+R+ D  G+ +    +G +  RGPYTI GYY L E N ++F+ DGFY+TGD 
Sbjct  365  RPLSPDDEVRVVDAEGREVGPGEVGELTVRGPYTIRGYYRLPEHNAKAFSADGFYRTGDR  424

Query  426  GYLDDDLNIVVTGREKEQINRSGEKVTPSEIEEFILQYPTVKDVCVIGVSDEHLGERIKA  485
               D D  +VV GR+K+QINR GEK+   E+E  ++ +P V D  V+ + D  LGER  A
Sbjct  425  VSRDKDGYLVVEGRDKDQINRGGEKIAAEEVENLLIAHPQVHDATVVAMPDSLLGERTCA  484

Query  486  IIIPKHEDHEISLKNIRKFLTGKNIAHFKIPDEIDVVADFKYTHVGKVNRQKL  538
             +IP+      S   ++++L    +A FK+PD I++V  F  T +GK++++ L
Sbjct  485  FVIPRQP--APSALKLKQYLHACGLAAFKVPDRIELVPAFPQTGIGKISKKDL  535


 Score = 23.9 bits (50),  Expect = 0.18
 Identities = 17/71 (24%), Positives = 32/71 (45%), Gaps = 12/71 (17%)

Query  9    QGYVPFPESRAKQYRAEGCWKSNTHFQ-----------MLADSVSRFGDCIAAIQDQKQL  57
            +GY   PE  AK + A+G +++                   D ++R G+ IAA + +  L
Sbjct  400  RGYYRLPEHNAKAFSADGFYRTGDRVSRDKDGYLVVEGRDKDQINRGGEKIAAEEVENLL  459

Query  58   -TYKQLYDYAI  67
              + Q++D  +
Sbjct  460  IAHPQVHDATV  470


>Q8XBV3 Enterobactin synthase component E [Escherichia coli O157:H7]
Length=536

 Score = 349 bits (895),  Expect = 1e-117
 Identities = 206/538 (38%), Positives = 299/538 (56%), Gaps = 25/538 (5%)

Query  12   VPF---PESRAKQYRAEGCWKSNTHFQMLADSVSRFG--DCIAAIQDQKQLTYKQLYDYA  66
            +PF   PE  A++YR +G W+       L D ++R    D IA I  ++QL+Y++L   A
Sbjct  3    IPFTRWPEEFARRYREKGYWQDLP----LTDILTRHAASDSIAVIDGERQLSYRELNQAA  58

Query  67   IRYGAYLKHKGIRETDFVLLQSPNVIEVFIVIFGLYAIGARPVFCLHGHGAYEIENIARQ  126
                  L+ +GI+  +  L+Q  NV E++I  F L  +G  PV  L  H   E+   A Q
Sbjct  59   DNLACSLRRQGIKPGETALVQLGNVAELYITFFALLKLGVAPVLALFSHQRSELNAYASQ  118

Query  127  SRAVGFIK----LCGTANEITAVDVCEEFSVPNFQLWFRETILSQETIAGSLPQLKHLNL  182
                  I        + ++     V E  S+       R   L  ++   +L    +   
Sbjct  119  IEPALLIADRQHALFSGDDFLNTFVAEHSSI-------RVVQLLNDSGEHNLQDAINHPA  171

Query  183  DTNIQALSSSEDIAFLQLSGGTTGLPKLIPRTHADYIYSIEKSVEVAGLNPQTKQLVVLP  242
            D      S ++++ + QLSGGTTG PKLIPRTH DY YS+ +SVE+     QT+ L  +P
Sbjct  172  DGFTATPSPADEVVYFQLSGGTTGTPKLIPRTHNDYYYSVRRSVEICQFTQQTRYLCAIP  231

Query  243  VMHNFCMSSPGFLGVFYAGGTVVLSQLTQPRVCFELIQKYKIEQVSLVPAIATLWLNA--  300
              HN+ MSSPG LGVF AGGTVVL+      +CF LI+K++I   +LVP   +LWL A  
Sbjct  232  AAHNYAMSSPGSLGVFLAGGTVVLAADPSATLCFPLIEKHQINVTALVPPAVSLWLQALT  291

Query  301  ESLKDYDLSSLKVIQVGGAKLLPSLAEQIIDQFQVKLQQVYGMAEGLVNFTHLDDTNAVT  360
            E      L+SLK++QVGGA+L  +LA +I  +   +LQQV+GMAEGLVN+T LDD+    
Sbjct  292  EGESRAQLASLKLLQVGGARLSATLAARIPAEIGCQLQQVFGMAEGLVNYTRLDDSAEKI  351

Query  361  IQTQGKKLSHLDEIRITDHHGQALPINAIGHIQTRGPYTINGYYNLHEINRRSFTDDGFY  420
            I TQG  +   DE+ + D  G  LP   +G + TRGPYT  GYY   + N  +F  +GFY
Sbjct  352  IHTQGYPMCPDDEVWVADAEGNPLPQGEVGRLMTRGPYTFRGYYKSPQHNASAFDANGFY  411

Query  421  KTGDIGYLDDDLNIVVTGREKEQINRSGEKVTPSEIEEFILQYPTVKDVCVIGVSDEHLG  480
             +GD+  +D +  I V GREK+QINR GEK+   EIE  +L++P V    ++ + DE +G
Sbjct  412  CSGDLISIDPEGYITVQGREKDQINRGGEKIAAEEIENLLLRHPAVIYAALVSMEDELMG  471

Query  481  ERIKAIIIPKHEDHEISLKNIRKFLTGKNIAHFKIPDEIDVVADFKYTHVGKVNRQKL  538
            E+  A ++ K     +    +R+FL  + IA FK+PD ++ V     T VGKV++++L
Sbjct  472  EKSCAYLVVK---EPLRAVQVRRFLREQGIAEFKLPDRVECVDSLPLTAVGKVDKKQL  526


>P10378 Enterobactin synthase component E [Escherichia coli (strain 
K12)]
Length=536

 Score = 349 bits (895),  Expect = 1e-117
 Identities = 207/538 (38%), Positives = 299/538 (56%), Gaps = 25/538 (5%)

Query  12   VPF---PESRAKQYRAEGCWKSNTHFQMLADSVSRFG--DCIAAIQDQKQLTYKQLYDYA  66
            +PF   PE  A++YR +G W+       L D ++R    D IA I  ++QL+Y++L   A
Sbjct  3    IPFTRWPEEFARRYREKGYWQDLP----LTDILTRHAASDSIAVIDGERQLSYRELNQAA  58

Query  67   IRYGAYLKHKGIRETDFVLLQSPNVIEVFIVIFGLYAIGARPVFCLHGHGAYEIENIARQ  126
                  L+ +GI+  +  L+Q  NV E++I  F L  +G  PV  L  H   E+   A Q
Sbjct  59   DNLACSLRRQGIKPGETALVQLGNVAELYITFFALLKLGVAPVLALFSHQRSELNAYASQ  118

Query  127  SRAVGFI----KLCGTANEITAVDVCEEFSVPNFQLWFRETILSQETIAGSLPQLKHLNL  182
                  I        + ++     V E  S+   QL      L+          + H   
Sbjct  119  IEPALLIADRQHALFSGDDFLNTFVTEHSSIRVVQL------LNDSGEHNLQDAINHPAE  172

Query  183  DTNIQALSSSEDIAFLQLSGGTTGLPKLIPRTHADYIYSIEKSVEVAGLNPQTKQLVVLP  242
            D      S ++++A+ QLSGGTTG PKLIPRTH DY YS+ +SVE+     QT+ L  +P
Sbjct  173  DFTATP-SPADEVAYFQLSGGTTGTPKLIPRTHNDYYYSVRRSVEICQFTQQTRYLCAIP  231

Query  243  VMHNFCMSSPGFLGVFYAGGTVVLSQLTQPRVCFELIQKYKIEQVSLVPAIATLWLNA--  300
              HN+ MSSPG LGVF AGGTVVL+      +CF LI+K+++   +LVP   +LWL A  
Sbjct  232  AAHNYAMSSPGSLGVFLAGGTVVLAADPSATLCFPLIEKHQVNVTALVPPAVSLWLQALI  291

Query  301  ESLKDYDLSSLKVIQVGGAKLLPSLAEQIIDQFQVKLQQVYGMAEGLVNFTHLDDTNAVT  360
            E      L+SLK++QVGGA+L  +LA +I  +   +LQQV+GMAEGLVN+T LDD+    
Sbjct  292  EGESRAQLASLKLLQVGGARLSATLAARIPAEIGCQLQQVFGMAEGLVNYTRLDDSAEKI  351

Query  361  IQTQGKKLSHLDEIRITDHHGQALPINAIGHIQTRGPYTINGYYNLHEINRRSFTDDGFY  420
            I TQG  +   DE+ + D  G  LP   +G + TRGPYT  GYY   + N  +F  +GFY
Sbjct  352  IHTQGYPMCPDDEVWVADAEGNPLPQGEVGRLMTRGPYTFRGYYKSPQHNASAFDANGFY  411

Query  421  KTGDIGYLDDDLNIVVTGREKEQINRSGEKVTPSEIEEFILQYPTVKDVCVIGVSDEHLG  480
             +GD+  +D +  I V GREK+QINR GEK+   EIE  +L++P V    ++ + DE +G
Sbjct  412  CSGDLISIDPEGYITVQGREKDQINRGGEKIAAEEIENLLLRHPAVIYAALVSMEDELMG  471

Query  481  ERIKAIIIPKHEDHEISLKNIRKFLTGKNIAHFKIPDEIDVVADFKYTHVGKVNRQKL  538
            E+  A ++ K     +    +R+FL  + IA FK+PD ++ V     T VGKV++++L
Sbjct  472  EKSCAYLVVK---EPLRAVQVRRFLREQGIAEFKLPDRVECVDSLPLTAVGKVDKKQL  526


>Q7X279 Salicylyl-CoA synthase / salicylate adenylyltransferase 
[Streptomyces sp]
Length=553

 Score = 321 bits (822),  Expect = 2e-106
 Identities = 187/541 (35%), Positives = 289/541 (53%), Gaps = 14/541 (3%)

Query  8    QQGYVPFPESRAKQYRAEGCWKSNTHFQMLADSVSRFGDCIAAIQDQKQLTYKQLYDYAI  67
            ++G+VP+P+  A +YR  G W+       L +    +GD +A +    +LTY+QL D A 
Sbjct  3    REGFVPWPKEAADRYREAGYWRGRPLGSYLHEWAETYGDTVAVVDGDTRLTYRQLVDRAD  62

Query  68   RYGAYLKHKGIRETDFVLLQSPNVIEVFIVIFGLYAIGARPVFCLHGHGAYEIENIARQS  127
                 L   G+   D +L+Q PN  E   +       G  PV  +  H  +E+  +A  +
Sbjct  63   GLACRLLDSGLNPGDAMLVQLPNGWEFVTLTLACLRAGIAPVMAMPAHRGHELRYLAAHA  122

Query  128  RAVGFI---KLCGTANEITAVDVCEEFSVPNFQLWFRETILSQETIAGSL------PQLK  178
                     +L    ++    +V E+       L    T+ +  T   +L      P   
Sbjct  123  EVTSIAVPDRLGDFDHQALGREVAEDTPSVGLLLVAGGTVGTDATDLRALAEPADDPVTA  182

Query  179  HLNLDTNIQALSSSEDIAFLQLSGGTTGLPKLIPRTHADYIYSIEKSVEVAGLNPQTKQL  238
               LD   +    S DIA   LSGGTTGLPKLI RTH DY Y+  +S EV GL+  +  L
Sbjct  183  RARLD---RIAPDSGDIAVFLLSGGTTGLPKLITRTHDDYEYNARRSAEVCGLDSDSVYL  239

Query  239  VVLPVMHNFCMSSPGFLGVFYAGGTVVLSQLTQPRVCFELIQKYKIEQVSLVPAIATLWL  298
            V LP  HNF ++ PG LG    GG VVL++  +P     L+    +   + VPA+   W+
Sbjct  240  VALPAGHNFPLACPGILGTLMNGGRVVLARTPEPGKVLPLMAAEGVTATAAVPAVVQRWI  299

Query  299  NAESLKDYDLS-SLKVIQVGGAKLLPSLAEQIIDQFQVKLQQVYGMAEGLVNFTHLDDTN  357
            +A +   +    +L+++QVGGA+L P +A +        LQQV+GMAEGL+N+T  DD +
Sbjct  300  DAVASGRHPAPPALRLLQVGGARLAPEVARRAEPVLGGTLQQVFGMAEGLLNYTRPDDPD  359

Query  358  AVTIQTQGKKLSHLDEIRITDHHGQALPINAIGHIQTRGPYTINGYYNLHEINRRSFTDD  417
             + I+TQG+ +   DEI + D     +P   +G + TRGPYT  GYY   E N R+FT D
Sbjct  360  DIKIETQGRPMCPDDEILVVDASDNPVPPGEMGALLTRGPYTPRGYYRAAEHNARAFTPD  419

Query  418  GFYKTGDIGYLDDDLNIVVTGREKEQINRSGEKVTPSEIEEFILQYPTVKDVCVIGVSDE  477
            G+Y+TGD+  L    N+VV GR+K+ INR GEK++  E+E  I + P V  V  +  +D 
Sbjct  420  GWYRTGDVVRLHPSGNLVVEGRDKDLINRGGEKISAEEVENLIYRLPGVARVAAVAKADP  479

Query  478  HLGERIKAIIIPKHEDHEISLKNIRKFLTGKNIAHFKIPDEIDVVADFKYTHVGKVNRQK  537
             LGER+ A+++ +    ++SL+++R  LT   +A +K+P+++ VV +   T VGK+++++
Sbjct  480  DLGERVCAVVVVE-PGTQLSLESVRAALTAMQVARYKLPEDLLVVDELPLTKVGKIDKKR  538

Query  538  L  538
            L
Sbjct  539  L  539


>Q1IAK8 Pseudomonine synthase PmsE [Pseudomonas entomophila (strain 
L48)]
Length=611

 Score = 320 bits (820),  Expect = 2e-105
 Identities = 189/534 (35%), Positives = 288/534 (54%), Gaps = 15/534 (3%)

Query  11   YVPFPESRAKQYRAEGCWKSNTHFQMLADSVSRFGDCIAAIQDQKQLTYKQLYDYAIRYG  70
            +  +P+ RA++YR  G W      ++L          +A I  +++ TY +L   +    
Sbjct  5    FTDWPQDRAQRYRDAGYWIDQPLTEILHSRCQAQPQALAIICGERRFTYGELDTLSSILA  64

Query  71   AYLKHKGIRETDFVLLQSPNVIEVFIVIFGLYAIGARPVFCLHGHGAYEIENIARQSRAV  130
            + L  +G+ + D  L+Q PNV E +IV+F L   G  P+  L  H   E+   A+Q   V
Sbjct  65   SRLAEQGLGQGDTALVQLPNVAEFYIVLFALLKAGIVPLNALFSHRRLELTAYAKQ--IV  122

Query  131  GFIKLCGTANEITAVDV-----CEEFSVPNFQLWFRETILSQETIAGSLPQ-LKHLNLDT  184
              + +    +E+   D       E  + P   L     +L +   A SL   ++      
Sbjct  123  PKLLIASREHEVFRDDAYVQAFAEVGAAPAVTL-----LLGESDPAASLAHWIETPGSQP  177

Query  185  NIQALSSSEDIAFLQLSGGTTGLPKLIPRTHADYIYSIEKSVEVAGLNPQTKQLVVLPVM  244
               A ++++ +A  QLSGG+TG+PKLIPRTH DY Y+     +V  LN  T+ L  +P  
Sbjct  178  VAYAPTAADQVALFQLSGGSTGIPKLIPRTHNDYHYNARACADVCALNAHTRFLCAVPAA  237

Query  245  HNFCMSSPGFLGVFYAGGTVVLSQLTQPRVCFELIQKYKIEQVSLVPAIATLWLNAESLK  304
            HNF +SSPG LGVF+AGG VV++   +P  CF L++++++  V+LVP+   LWL A    
Sbjct  238  HNFLLSSPGALGVFHAGGCVVMAASPEPLSCFALVEQHEVNTVALVPSAVALWLQAAPAH  297

Query  305  DYDLSSLKVIQVGGAKLLPSLAEQIIDQFQVKLQQVYGMAEGLVNFTHLDDTNAVTIQTQ  364
               L SL  +QVGGA    SLA Q+      +LQQV+GMAEGL+N+T LDD++     TQ
Sbjct  298  RDKLQSLAYLQVGGAVFADSLARQVPGVLGCQLQQVFGMAEGLINYTRLDDSDEQIFTTQ  357

Query  365  GKKLSHLDEIRITDHHGQALPINAIGHIQTRGPYTINGYYNLHEINRRSFTDDGFYKTGD  424
            G+ +S  DEI+I D  G  +     G + TRGPYT  GYY   E N  +F  +GFY +GD
Sbjct  358  GRPVSPDDEIKIVDEQGVPVAPGEPGMLATRGPYTFCGYYKAPEQNASAFDAEGFYYSGD  417

Query  425  IGYLDDDLNIVVTGREKEQINRSGEKVTPSEIEEFILQYPTVKDVCVIGVSDEHLGERIK  484
            +  L    ++ V GR K+QINR GEKV   EIE  ++ +P V    ++ + DE LGE+  
Sbjct  418  LVVLTPSGDLRVVGRIKDQINRGGEKVASEEIENLLVLHPEVTHAGLVAMPDEALGEKSC  477

Query  485  AIIIPKHEDHEISLKNIRKFLTGKNIAHFKIPDEIDVVADFKYTHVGKVNRQKL  538
            A ++ ++    +    +R+ L    IA +K+PD I ++     T VGK+++++L
Sbjct  478  AFVVSRNP--SLKAPALRRHLMELGIAEYKLPDRIRLIEAMPLTAVGKIDKKQL  529


 Score = 21.2 bits (43),  Expect = 1.2
 Identities = 19/93 (20%), Positives = 38/93 (41%), Gaps = 11/93 (12%)

Query  10   GYVPFPESRAKQYRAEGCWKSNTHFQM-----------LADSVSRFGDCIAAIQDQKQLT  58
            GY   PE  A  + AEG + S     +           + D ++R G+ +A+ + +  L 
Sbjct  395  GYYKAPEQNASAFDAEGFYYSGDLVVLTPSGDLRVVGRIKDQINRGGEKVASEEIENLLV  454

Query  59   YKQLYDYAIRYGAYLKHKGIRETDFVLLQSPNV  91
                  +A       +  G +   FV+ ++P++
Sbjct  455  LHPEVTHAGLVAMPDEALGEKSCAFVVSRNPSL  487


>Q84HC5 2-hydroxy-7-methoxy-5-methyl-1-naphthoate--CoA ligase 
[Streptomyces carzinostaticus]
Length=558

 Score = 311 bits (797),  Expect = 1e-102
 Identities = 185/551 (34%), Positives = 289/551 (52%), Gaps = 36/551 (7%)

Query  10   GYVPFPESRAKQYRAEGCWKSNTHFQMLADSVSRFGDCIAAIQDQKQLTYKQLYDYAIRY  69
            G+VP+P+  A +Y A G W+  +    LA++  +  + +  +    +++Y +L   A   
Sbjct  12   GFVPWPDDVAARYTAAGHWEGRSLGTHLAEAARKVPEAVCLVDGPVRMSYSELMARADGA  71

Query  70   GAYLKHKGIRETDFVLLQSPNVIEVFIVIFGLYAIGARPVFCLHGHGAYEIENIARQSRA  129
               ++  GIR  D V++Q PN  E  +V      +GA P++ L  +   E+  +   +RA
Sbjct  72   AVRMRGLGIRPADRVVVQLPNCWEHVVVTMACLRLGALPIWALPQYRHRELSGVVTHARA  131

Query  130  VGFIKLCGTANEITAVDVCEEFSVPNFQLWFRETILSQETI-----AGSLPQLKHLNLDT  184
                      + +   DV  EF   + Q    E   +Q T+     AGS  +   ++L  
Sbjct  132  ----------SALVVPDVYREF---DHQALAHEVAEAQPTVRHVLVAGSDVRPDSVDLRA  178

Query  185  NIQALSSSE----------------DIAFLQLSGGTTGLPKLIPRTHADYIYSIEKSVEV  228
              + L + E                ++A L+LSGGTTGLPKL+ RTH D  Y I+++ +V
Sbjct  179  LCEPLDADEAARVAAELDRSAPRGEEVAMLKLSGGTTGLPKLVARTHNDLSYMIKRAAQV  238

Query  229  AGLNPQTKQLVVLPVMHNFCMSSPGFLGVFYAGGTVVLSQLTQPRVCFELIQKYKIEQVS  288
             G    T  L VLP+ H F  + PG LG   AGG VV+S    P   F L+++ ++   S
Sbjct  239  CGFGRDTVYLAVLPLGHGFPNTGPGVLGTLLAGGRVVISGSPAPEAAFALMERERVTATS  298

Query  289  LVPAIATLWLN-AESLKDYDLSSLKVIQVGGAKLLPSLAEQIIDQFQVKLQQVYGMAEGL  347
            +VPAI   WL   +     DL SL+++QVG ++L P +A Q+  +   +LQQV+GMAEGL
Sbjct  299  VVPAIVMRWLQYRDERPGADLGSLELMQVGASRLEPEVARQVGPKLGCRLQQVFGMAEGL  358

Query  348  VNFTHLDDTNAVTIQTQGKKLSHLDEIRITDHHGQALPINAIGHIQTRGPYTINGYYNLH  407
            +  T LDD + V   TQG+ +S  DEIR+ D  G+ + +   G + TRGPYT  GYY+  
Sbjct  359  LCLTRLDDPDDVVHYTQGRPISPDDEIRVVDPEGRTVGVGEPGALLTRGPYTPRGYYDSP  418

Query  408  EINRRSFTDDGFYKTGDIGYLDDDLNIVVTGREKEQINRSGEKVTPSEIEEFILQYPTVK  467
              N R+FT DG+Y+TGD+     D N++V GREK+ INR GEK+   E+E F +Q   V 
Sbjct  419  SANARAFTPDGWYRTGDLVRRTPDGNLIVVGREKDLINRGGEKINAEEVEGFAVQVDGVL  478

Query  468  DVCVIGVSDEHLGERIKAIIIPKHEDHEISLKNIRKFLTGKNIAHFKIPDEIDVVADFKY  527
                +G+ D  LGERI  + +   +   + L ++RK +     A FK+P+ +  +     
Sbjct  479  QAAAVGLPDSELGERI-CLFVVLADGTRVELADVRKVMENAETASFKLPERLITLPSLPT  537

Query  528  THVGKVNRQKL  538
            T +GK++++ L
Sbjct  538  TPMGKIDKKAL  548


>P71716 Salicyl-AMP ligase / salicyl-S-ArCP synthetase [Mycobacterium 
tuberculosis (strain ATCC 25618 / H37Rv)]
Length=565

 Score = 309 bits (791),  Expect = 9e-102
 Identities = 190/552 (34%), Positives = 282/552 (51%), Gaps = 45/552 (8%)

Query  10   GYVPFPESRAKQYRAEGCWKSNTHFQMLADSVSRFGDCIAAIQDQKQ-----LTYKQLYD  64
            G+VPFP  RA  YRA G W   T   +L+D+  R+ D +A      +     L+Y +L  
Sbjct  19   GFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAELDQ  78

Query  65   YAIRYGAYLKHKGIRETDFVLLQSPNVIEVFIVIFGLYAIGARPVFCLHGHGAYEIENIA  124
             A R  A L   GI   D VLLQ PN  +  + +F L   GA PV CL GH A E+ + A
Sbjct  79   RADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGHFA  138

Query  125  RQSRAVGFIKLCGTANEITAVDVCEEFSVPNFQLWFRETILSQETIAGSLPQLKHLNLDT  184
              S A G +            DV   F   +++   RE +          P L+H+ +D 
Sbjct  139  AVSAATGLV----------VADVASGF---DYRPMARELVADH-------PTLRHVIVDG  178

Query  185  NIQALSSSEDI------------------AFLQLSGGTTGLPKLIPRTHADYIYSIEKSV  226
            +     S   +                  A L +SGGTTG+PKLIPRTH DY+++   S 
Sbjct  179  DPGPFVSWAQLCAQAGTGSPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASA  238

Query  227  EVAGLNPQTKQLVVLPVMHNFCMSSPGFLGVFYAGGTVVLSQLTQPRVCFELIQKYKIEQ  286
             +  L+     LVVL   HNF ++ PG LG    G T V +    P   F  I+++ +  
Sbjct  239  ALCRLSADDVYLVVLAAGHNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTV  298

Query  287  VSLVPAIATLWLNAESLKDYDLSSLKVIQVGGAKLLPSLAEQIIDQFQVKLQQVYGMAEG  346
             +LVPA+A LW  +   +     SL+++QVGG+KL P  A ++       LQQV+GMAEG
Sbjct  299  TALVPALAKLWAQSCEWEPVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEG  358

Query  347  LVNFTHLDDTNAVTIQTQGKKLSHLDEIRITDHHGQALPINAIGHIQTRGPYTINGYYNL  406
            L+NFT + D   V   TQG+ L   DE+RI +  G+ +     G +  RGPYT+NGY+  
Sbjct  359  LLNFTRIGDPPEVVEHTQGRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAA  418

Query  407  HEINRRSFTDDGFYKTGDIGYLDDDLNIVVTGREKEQINRSGEKVTPSEIEEFILQYPTV  466
               N R F  DGFY++GD+    DD N+VVTGR K+ I R+GE +  S++EE +L +P +
Sbjct  419  ERDNERCFDPDGFYRSGDLVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAI  478

Query  467  KDVCVIGVSDEHLGERIKAIIIPKHEDHEISLKNIRKFLTGKNIAHFKIPDEIDVVADFK  526
                 +G+ D++LGE+I A ++       I+L  +  +L  + +A    PD++  +    
Sbjct  479  FSAAAVGLPDQYLGEKICAAVV--FAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALP  536

Query  527  YTHVGKVNRQKL  538
             T +GK++++ +
Sbjct  537  TTPIGKIDKRAI  548


>P80436 Triostin synthetase I [Streptomyces triostinicus]
Length=527

 Score = 302 bits (773),  Expect = 1e-99
 Identities = 187/544 (34%), Positives = 281/544 (52%), Gaps = 44/544 (8%)

Query  10   GYVPFPESRAKQYRAEGCWKSNTHFQMLADSVSRFGDCIAAIQDQKQLTYKQLYDYAIRY  69
            G+VP+P+  A +YR  G W       +L DS  R  D +A + D  ++TY +L   A R 
Sbjct  4    GFVPWPDHLADEYRRRGIWLGRPLGDLLHDSCRRHADRVAVVCDGHRMTYAELSRRADRL  63

Query  70   GAYLKHKGIRETDFVLLQSPNVIEVFIVIFGLYAIGARPVFCLHGHGAYEIENIARQSRA  129
               L   GIR  D V++  PN+ E  +++F L   GA PV  L GH   EI ++   S A
Sbjct  64   AGGLIGLGIRPLDRVVVHLPNIPEFVVLVFALLRAGAIPVLALPGHRKSEISHLCAHSGA  123

Query  130  VGFIKLCGTANEITAVDVCEEFSVPNFQLWFRETILSQETIAGSLPQLKHLNLDTNIQAL  189
            V +              V +EF   +++   RE           +P ++H+ +  + Q  
Sbjct  124  VAYA-------------VKDEFGGFDYRELARE-----------IPPVRHVLVSGDAQEF  159

Query  190  SSSEDI---------------AFLQLSGGTTGLPKLIPRTHADYIYSIEKSVEVAGLNPQ  234
            ++ E +               A   LSGGTTGLPKLIPR H DY Y +  + E   +  +
Sbjct  160  TALESVGGDDVPLPRVDPSDPALFLLSGGTTGLPKLIPRAHDDYAYVMRATAEAMHVGEE  219

Query  235  TKQLVVLPVMHNFCMSSPGFLGVFYAGGTVVLSQLTQPRVCFELIQKYKIEQVSLVPAIA  294
               L V PV H   ++ PG  G    GG  VL+   +P   F LI++  +   ++VP++ 
Sbjct  220  VAYLAVNPVAHQAALACPGVFGSLLLGGKAVLTSSVRPDEVFPLIRREHVTVTTVVPSVL  279

Query  295  TLWLNAESLKDYDLSSLKVIQVGGAKLLPSLAEQIIDQFQVKLQQVYGMAEGLVNFTHLD  354
             LW  A+S +  DLS L ++QVG A L P+LA +  +    ++ + YG++EGL+  T  D
Sbjct  280  RLW--ADSGQRPDLSHL-LVQVGSAPLDPALARRAGEVLGCRIMRWYGISEGLLTHTRFD  336

Query  355  DTNAVTIQTQGKKLSHLDEIRITDHHGQALPINAIGHIQTRGPYTINGYYNLHEINRRSF  414
            D   V + T G+ +S  DE+RI D     +P    G +  RGPYTI GYY   E N RSF
Sbjct  337  DPEDVIMGTDGRPMSRDDEVRIVDESLNPVPEGEAGEMIARGPYTIRGYYRAPEENTRSF  396

Query  415  TDDGFYKTGDIGYLDDDLNIVVTGREKEQINRSGEKVTPSEIEEFILQYPTVKDVCVIGV  474
            T DGF++TGD+     + +I + GR K+ INR+GEKV+  E+E  +  +P+V+D  V+GV
Sbjct  397  TPDGFFRTGDLVRRSPEGDITIVGRIKDVINRAGEKVSAEEVERQLRTHPSVQDAAVVGV  456

Query  475  SDEHLGERIKAIIIPKHEDHEISLKNIRKFLTGKNIAHFKIPDEIDVVADFKYTHVGKVN  534
             D  LGER  A ++      +I    +++FL G  +A +KIPD I  +     T +GKV+
Sbjct  457  PDTVLGERTYAFLV--LTGAQIRTSAVKEFLRGCGLATYKIPDRIVPLDQLPRTPMGKVD  514

Query  535  RQKL  538
            ++ L
Sbjct  515  KKTL  518


 Score = 23.5 bits (49),  Expect = 0.24
 Identities = 15/71 (21%), Positives = 34/71 (48%), Gaps = 12/71 (17%)

Query  9    QGYVPFPESRAKQYRAEGCWKSN-----------THFQMLADSVSRFGDCIAAIQDQKQL  57
            +GY   PE   + +  +G +++            T    + D ++R G+ ++A + ++QL
Sbjct  383  RGYYRAPEENTRSFTPDGFFRTGDLVRRSPEGDITIVGRIKDVINRAGEKVSAEEVERQL  442

Query  58   -TYKQLYDYAI  67
             T+  + D A+
Sbjct  443  RTHPSVQDAAV  453


>P38135 Medium-chain fatty-acid--CoA ligase [Escherichia coli 
(strain K12)]
Length=566

 Score = 176 bits (446),  Expect = 1e-51
 Identities = 145/531 (27%), Positives = 237/531 (45%), Gaps = 18/531 (3%)

Query  14   FPESRAKQYRAEGCWKSNTHFQMLADSVSRFGDCIAAIQDQ-KQLTYKQLYDYAIRYGAY  72
            F E R   YR +G W   +       +     D IA + +     TY  L   A     +
Sbjct  25   FNEQRRAAYRQQGLWGDASLADYWQQTARAMPDKIAVVDNHGASYTYSALDHAASCLANW  84

Query  73   LKHKGIRETDFVLLQSPNVIEVFIVIFGLYAIGARPVFCLHGHGAYEIENIARQSRAVGF  132
            +  KGI   D +  Q P   E  ++      IGA  V  L      E+  +  + +A  F
Sbjct  85   MLAKGIESGDRIAFQLPGWCEFTVIYLACLKIGAVSVPLLPSWREAELVWVLNKCQAKMF  144

Query  133  IKLCGTANEITAVDVCEEFS--VPNFQLWFRETILSQETIAGSLPQLKHLNLDTNIQALS  190
                    +   VD+       +P  Q       L+  T + SL Q+   N        +
Sbjct  145  FAPT-LFKQTRPVDLILPLQNQLPQLQQIVGVDKLAPATSSLSLSQIIADNTSLTTAITT  203

Query  191  SSEDIAFLQLSGGTTGLPKLIPRTHADYIYSIEKSVEVAGLNPQTKQLVVLPVMHNFCMS  250
              +++A +  + GT GLPK +  TH + + S         L  Q   ++  P+ H     
Sbjct  204  HGDELAAVLFTSGTEGLPKGVMLTHNNILASERAYCARLNLTWQDVFMMPAPLGH-----  258

Query  251  SPGFL-GV---FYAGGTVVLSQLTQPRVCFELIQKYKIE-QVSLVPAIATLWLNAESLKD  305
            + GFL GV   F  G   VL  +  P  C  L+++ +    +   P +  L LN    + 
Sbjct  259  ATGFLHGVTAPFLIGARSVLLDIFTPDACLALLEQQRCTCMLGATPFVYDL-LNVLEKQP  317

Query  306  YDLSSLKVIQVGGAKLLPSLAEQIIDQFQVKLQQVYGMAEGLVN-FTHLDDTNAVTIQTQ  364
             DLS+L+    GG  +   +A +   Q  +KL  VYG  E   +   +LDD  +  + T 
Sbjct  318  ADLSALRFFLCGGTTIPKKVAREC-QQRGIKLLSVYGSTESSPHAVVNLDDPLSRFMHTD  376

Query  365  GKKLSHLDEIRITDHHGQALPINAIGHIQTRGPYTINGYYNLHEINRRSFTDDGFYKTGD  424
            G   + + EI++ D   + LP    G   +RGP    GY++  E+  R+  ++G+Y +GD
Sbjct  377  GYAAAGV-EIKVVDDARKTLPPGCEGEEASRGPNVFMGYFDEPELTARALDEEGWYYSGD  435

Query  425  IGYLDDDLNIVVTGREKEQINRSGEKVTPSEIEEFILQYPTVKDVCVIGVSDEHLGERIK  484
            +  +D+   I +TGR+K+ I R GE ++  E+E+ +LQ+P + D CV+ +SDE LGER  
Sbjct  436  LCRMDEAGYIKITGRKKDIIVRGGENISSREVEDILLQHPKIHDACVVAMSDERLGERSC  495

Query  485  AIIIPKHEDHEISLKNIRKFLTGKNIAHFKIPDEIDVVADFKYTHVGKVNR  535
            A ++ K   H +SL+ +  F + K +A +K P+ I V+     T  GK+ +
Sbjct  496  AYVVLKAPHHSLSLEEVVAFFSRKRVAKYKYPEHIVVIEKLPRTTSGKIQK  546



Lambda      K        H        a         alpha
   0.322    0.139    0.410    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 2918104


  Database: 54a14e504c89a6b07850891a4e846d1a.SwissProt.fasta
    Posted date:  May 19, 2024  7:24 PM
  Number of letters in database: 6,628
  Number of sequences in database:  12



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40