BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: ead2a0000399eb037f7fb832f9bf13b4.SwissProt.fasta
11 sequences; 60,051 total letters
Query= ACIAD2771
Length=1067
Score E
Sequences producing significant alignments: (Bits) Value
P45745 Dimodular nonribosomal peptide synthase [Bacillus subtilis... 152 2e-39
Q70LM6 ATP-dependent D-leucine adenylase / Leucine racemase [ATP-... 151 5e-39
Q70LM5 ATP-dependent valine adenylase / ATP-dependent D-valine ad... 146 1e-37
Q70LM4 ATP-dependent D-leucine adenylase / Leucine racemase [ATP-... 143 1e-36
A0A348AXX4 Nonribosomal peptide synthetase [Curvularia clavata] 134 9e-34
P0DUV4 Malpibaldin synthetase [Mortierella alpina] 127 8e-32
Q00869 N-methylcyclopeptide synthetase / S-adenosyl-L-methionine-... 124 7e-31
A0A0A1EA36 Nonribosomal peptide synthetase / S-adenosyl-L-methion... 124 7e-31
C7ZBE4 Nonribosomal peptide synthetase 30 [Fusarium vanettenii (s... 120 2e-29
P39847 ATP-dependent glutamate adenylase 2 / ATP-dependent alanin... 116 2e-28
O68008 ATP-dependent isoleucine adenylase / ATP-dependent D-pheny... 116 2e-28
>P45745 Dimodular nonribosomal peptide synthase [Bacillus subtilis
(strain 168)]
Length=2378
Score = 152 bits (384), Expect = 2e-39
Identities = 137/533 (26%), Positives = 238/533 (45%), Gaps = 39/533 (7%)
Query 517 QLILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTALE 576
+++ D F +VL + DD+FF+ GGHS+LA R++ +++ G + IA F+ PT
Sbjct 968 EILCDLFAEVLGLARVGIDDSFFELGGHSLLAARLMSRIREVMGAELGIAKLFDEPTVAG 1027
Query 577 LSQCVEYLSDRVKDSSVADDNREIVAPLTLLQKAFMGFSN-QGRDAMYNIPFAFRFSETV 635
L+ ++ A+ +I PL+ Q+ +G YNIP A R S +
Sbjct 1028 LAAHLDLAQSACPALQRAERPEKI--PLSFAQRRLWFLHCLEGPSPTYNIPVAVRLSGEL 1085
Query 636 NEQAFYDAFLDILKRHHVMRSIFVQADQGEIFQTVIPMDRLNQHPWFWGSEHQVGQSAQQ 695
++ A D++ RH +R+IF ++ QG +Q ++ DR E V + A++
Sbjct 1086 DQGLLKAALYDLVCRHESLRTIFPES-QGTSYQHILDADRACP-------ELHVTEIAEK 1137
Query 696 ILR---AEA-NHSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQA 751
L AEA +SFDL E R +++L +L++HI D WS L R+L A
Sbjct 1138 ELSDRLAEAVRYSFDLAAEPAFRAELFVIGPDEYVLLLLVHHIVGDGWSLTPLTRDLGTA 1197
Query 752 YTSRVDGKAPIWEKTPRQFHEYAMAQDD---------SALQAHIQYWMNTIGKIKKQQPL 802
Y +R G++P W Q+ +YA+ Q + S + + +W T+ + Q L
Sbjct 1198 YAARCHGRSPEWAPLAVQYADYALWQQELLGNEDDPNSLIAGQLAFWKETLKNLPDQLEL 1257
Query 803 LPAYRNDVDMPPPENNLDDVSGAAVEFNFTAIQVEQLYALARQYRSSLFYVVYAGLLLTT 862
Y P E + D G + F ++L LAR R SLF V+ +GL
Sbjct 1258 PTDYSR-----PAEPSHD---GDTIHFRIEPEFHKRLQELARANRVSLFMVLQSGLAALL 1309
Query 863 YYLGAGKKVLSGTSVACRQDPNYQDTLGYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKA 922
LGAG + G+ +A R D D +G F N ++ + S ++L+++V+ A
Sbjct 1310 TRLGAGTDIPIGSPIAGRNDDALGDLVGLFINTLVLRTDTSGDPSFRELLDRVREVNLAA 1369
Query 923 QEYADIPFAIVEDNIRAEGEEWTESPYEVYVQLHAQNALTGVFQLNSGDEIGFELIEPER 982
+ D+PF + + + T ++ + L QN L ++ L
Sbjct 1370 YDNQDLPFERLVEVLNPARSRATHPLFQ--IMLAFQNTPDAELHL---PDMESSLRINSV 1424
Query 983 DTAKFGLHFEVYEEPSSE--KERLRVVINYRVNRYNEIQIQLIRQVAQQVLES 1033
+AKF L E+ E+ ++ + ++ Y + + Q + ++LE+
Sbjct 1425 GSAKFDLTLEISEDRLADGTPNGMEGLLEYSTDLFKRETAQALADRLMRLLEA 1477
Score = 54.7 bits (130), Expect = 2e-09
Identities = 24/66 (36%), Positives = 42/66 (64%), Gaps = 0/66 (0%)
Query 517 QLILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTALE 576
+++ D F +VL P + DD FFD GGHS+LA +++ +++ G+ + I + F APT
Sbjct 2043 EILCDLFMEVLHLPRVGIDDRFFDLGGHSLLAVQLMSRIREALGVELSIGNLFEAPTVAG 2102
Query 577 LSQCVE 582
L++ +E
Sbjct 2103 LAERLE 2108
Score = 47.4 bits (111), Expect = 3e-07
Identities = 62/301 (21%), Positives = 131/301 (44%), Gaps = 34/301 (11%)
Query 60 WMLHQQDP---LASSGPFILAFRLSGEIEISRLSNAIQKLYEGDSNLNLRYDLDDEG--- 113
W Q DP + ++ +I ++G + I+ A++ + + +L++R+ + +G
Sbjct 19 WFAQQLDPDNPIYNTAEYI---EINGPVNIALFEEALRHVIKEAESLHVRFGENMDGPWQ 75
Query 114 ILNKYHDEHTPFEMNIHVVKSEQEAVQYLLSWIQ----KPINLAKAPAIQFTLLPQSHHE 169
++N D ++++ V SE + + L+W++ KP++L AP L
Sbjct 76 MINPSPD----VQLHVIDVSSEPDPEKTALNWMKADLAKPVDLGYAPLFNEALFIAGPDR 131
Query 170 VILGILGHHILLDDSAWQPIFAQLSQNY-AQLDGVLTASNSHIELSSKIPAKVLVNSQNA 228
HHI +D + I +++ Y A + G S S L + + + + +
Sbjct 132 FFWYQRIHHIAIDGFGFSLIAQRVASTYTALIKGQTAKSRSFGSLQAILEEDT--DYRGS 189
Query 229 LQYWKTIFPTGLNQLDWPKFCRAPNVQASIIQYGQNTIFDYEQKAVRCSSSIPLKGLKQL 288
QY K Q +F AP V S+ T + +R ++ +P + L
Sbjct 190 EQYEKD------RQFWLDRFADAPEV-VSLADRAPRTSNSF----LRHTAYLPPSDVNAL 238
Query 289 SERAQ---ASIFHTVVAQFGGYLNHLFGTQSIDLFVPIVEQYEASSLSQIRSSSNILPIR 345
E A+ S ++A Y++ + G++ + L +P++ + ++SL+ N+LP+R
Sbjct 239 KEAARYFSGSWHEVMIAVSAVYVHRMTGSEDVVLGLPMMGRIGSASLNVPAMVMNLLPLR 298
Query 346 I 346
+
Sbjct 299 L 299
Score = 46.2 bits (108), Expect = 6e-07
Identities = 39/150 (26%), Positives = 68/150 (45%), Gaps = 2/150 (1%)
Query 50 VQLSFTEERAWMLHQQDPLASSGPFILAFRLSGEIEISRLSNAIQKLYEGDSNLNLRYDL 109
+ LSF + R W LH + + + +A RLSGE++ L A+ L +L +
Sbjct 1051 IPLSFAQRRLWFLHCLEGPSPTYNIPVAVRLSGELDQGLLKAALYDLVCRHESLRTIFP- 1109
Query 110 DDEGILNKYHDEHTPFEMNIHVVK-SEQEAVQYLLSWIQKPINLAKAPAIQFTLLPQSHH 168
+ +G ++ + +HV + +E+E L ++ +LA PA + L
Sbjct 1110 ESQGTSYQHILDADRACPELHVTEIAEKELSDRLAEAVRYSFDLAAEPAFRAELFVIGPD 1169
Query 169 EVILGILGHHILLDDSAWQPIFAQLSQNYA 198
E +L +L HHI+ D + P+ L YA
Sbjct 1170 EYVLLLLVHHIVGDGWSLTPLTRDLGTAYA 1199
Score = 26.6 bits (57), Expect = 0.58
Identities = 71/422 (17%), Positives = 146/422 (35%), Gaps = 40/422 (9%)
Query 622 MYNIPFAFRFSETVNEQAFYDAFLDILKRHHVMRSIFVQADQGEIFQTVIPMDRLNQHPW 681
+YN + VN F +A ++K + F + G +Q + P + H
Sbjct 30 IYNTAEYIEINGPVNIALFEEALRHVIKEAESLHVRFGENMDGP-WQMINPSPDVQLHVI 88
Query 682 FWGSEHQVGQSAQQILRAEANHSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSS 741
SE ++A ++A+ DL + ++HIA+D +
Sbjct 89 DVSSEPDPEKTALNWMKADLAKPVDLGYAPLFNEALFIAGPDRFFWYQRIHHIAIDGFGF 148
Query 742 GILMRELIQAYTSRVDGKAPIWEKTPRQFHE-YAMAQDDSALQAHIQYWMNTIGKIKKQQ 800
++ + + YT+ + G+ R F A+ ++D+ + QY K +Q
Sbjct 149 SLIAQRVASTYTALIKGQT----AKSRSFGSLQAILEEDTDYRGSEQY-------EKDRQ 197
Query 801 PLLPAYRNDVDMPPPENNLDDVSGAAVEFN--FTAIQVEQLYALARQYRSSLFYVVYAGL 858
L + + ++ + S + + V L AR + S V+ A
Sbjct 198 FWLDRFADAPEVVSLADRAPRTSNSFLRHTAYLPPSDVNALKEAARYFSGSWHEVMIAVS 257
Query 859 LLTTYYLGAGKKVLSGTSVACRQDPNYQDTLGYFTNVVMHYIQFNESLSIKDLVNQVQNN 918
+ + + + V+ G + R + N++ + + S+S +L+ Q+
Sbjct 258 AVYVHRMTGSEDVVLGLPMMGRIGSASLNVPAMVMNLLPLRLTVSSSMSFSELIQQISRE 317
Query 919 IFKAQEYADI-------PFAIVEDNIRAEGEEWTESPYEVYVQLHAQNALTGVFQLNSGD 971
I + + ++ +N R G + P++ + T D
Sbjct 318 IRSIRRHHKYRHEELRRDLKLIGENHRLFGPQINLMPFDYGLDFAGVRGTTHNLSAGPVD 377
Query 972 EIGFELIEPERDTAKFGLHFEVYEEPSSEKERLRVVINYRVNRYNEIQIQLIRQVAQQVL 1031
+ L VY+ R+ V N V Y+E I+L +Q Q+L
Sbjct 378 D----------------LSINVYDRTDGSGLRIDVDANPEV--YSESDIKLHQQRILQLL 419
Query 1032 ES 1033
++
Sbjct 420 QT 421
>Q70LM6 ATP-dependent D-leucine adenylase / Leucine racemase [ATP-hydrolyzing]
/ ATP-dependent alanine adenylase / ATP-dependent
D-valine adenylase / Valine racemase [ATP-hydrolyzing]
[Brevibacillus parabrevis]
Length=5162
Score = 151 bits (381), Expect = 5e-39
Identities = 136/556 (24%), Positives = 242/556 (44%), Gaps = 32/556 (6%)
Query 497 QEHWAQPTSSVQPQVDASITQ-LILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKL 555
+ W Q S+ + T+ L+ + VL + DNFF+ GGHS+LATRV +L
Sbjct 3527 EPEWGQVASAAGYVAPRNQTEVLVASIWADVLGIEQVGVHDNFFELGGHSLLATRVASRL 3586
Query 556 QTQHGLLIKIADFFNAPTALELSQCVEYLSDRVKDSSVADDNREIVAPLTLLQKAFMGFS 615
+ + I F PT ELS+ + + ++ + +RE PL+ Q+
Sbjct 3587 RETFAKEVPIRAIFERPTVAELSETLGAIGQNETEAQMLPVSREAHLPLSFAQQRLWFLD 3646
Query 616 NQGRDA-MYNIPFAFRFSETVNEQAFYDAFLDILKRHHVMRSIFVQADQGEIFQTVIPM- 673
D+ +YNIP A R ++ A+ + +++RH +R+ F D GE Q +
Sbjct 3647 RLMPDSTLYNIPSAVRLLGDLDIAAWEKSLQVLIQRHESLRTTFGDVD-GEAVQVIHSRL 3705
Query 674 -DRLNQHPWFWGSEHQVGQSAQQILRAEANHSFDLMQEFPIRVRFMKDEQGQHILSMLLY 732
+LN + A ++ EA FDL Q +R ++ + + + L+
Sbjct 3706 DGKLNVIDLRGMPADEREAEAHRLAGLEAATPFDLSQGPLLRTTLIRLAEQECVFLFNLH 3765
Query 733 HIAMDEWSSGILMRELIQAYTSRVDGKAPIWEKTPRQFHEYAMAQ----DDSALQAHIQY 788
HI D WS GI ++E+ Y + V +AP + Q+ +YA+ Q + L + Y
Sbjct 3766 HIIFDGWSIGIFLKEMRALYEAFVREEAPELAEITVQYADYAVWQRKWLEGEVLAEQLAY 3825
Query 789 WMNTIGKIKKQQPLLPAYRNDVDMPPPENNLDDVSGAAVEFNFTAIQVEQLYALARQYRS 848
W K+ +PLL D P P D GA + +L L+++ +
Sbjct 3826 WKE---KLSGAEPLLAL---PTDQPRPAVQTHD--GAMHTIKLSGELYAKLNKLSQEEGA 3877
Query 849 SLFYVVYAGLLLTTYYLGAGKKVLSGTSVACRQDPNYQDTLGYFTNVVMHYIQFNESLSI 908
+LF + A + Y + +L G+ VA R + +G+F N ++ + +
Sbjct 3878 TLFMTLLAAFQVLLYRYSGQEDILVGSPVAGRNRQETEPLIGFFINTLVLRTDLSGEPTF 3937
Query 909 KDLVNQVQNNIFKAQEYADIPFAIVEDNIRAEGEEWTESPYEVYVQLHAQNALTGVFQLN 968
++L+ +V+ F+A + D+PF + D + E ++V L QN FQLN
Sbjct 3938 RELLARVRETAFEAYAHQDLPFEKLVDELELERSLSYSPLFQVMFVL--QN-----FQLN 3990
Query 969 SGDEIGFELIEPERD----TAKFGLHFEVYEEPSSEKERLRVVINYRVNRYNEIQIQLIR 1024
++ G + + E D T+K+ L + E+ + L Y ++E ++ +
Sbjct 3991 LDEKAGIRVADFEMDKHLVTSKYDLTLTMAEKQNG----LFATFEYNTALFHEATMERLS 4046
Query 1025 QVAQQVLESFIHIDTQ 1040
Q Q+LE+ +H+ Q
Sbjct 4047 QHFIQLLEAIVHMPDQ 4062
Score = 141 bits (356), Expect = 5e-36
Identities = 131/535 (24%), Positives = 236/535 (44%), Gaps = 36/535 (7%)
Query 515 ITQLILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTA 574
+ +L++ +++VL + DNFF+ GGHS+LAT+V+ + + + + + F T
Sbjct 968 VEELVVRIWEEVLNVSQVGVHDNFFELGGHSLLATQVLSRTAKLFHVRLPMREIFTHQTV 1027
Query 575 LELSQCVEYL-----SDRVKDSSVADDNREIVAPLTLLQKAFMGFSNQGRD-AMYNIPFA 628
EL++ ++ L +D+ + R PL+ Q+ D AMYNIP
Sbjct 1028 AELARRIQALRHGAEADKHSPIQPSALQRADELPLSYAQQRLWFLDRLIPDSAMYNIPVG 1087
Query 629 FRFSETVNEQAFYDAFLDILKRHHVMRSIFVQADQGEIFQTVIPMDRLNQHPWFWGSEHQ 688
FR TV+E A +I++RH +R+ FV D G Q + L+ +
Sbjct 1088 FRLRGTVDELVLERALNEIIQRHESLRTTFVDVD-GRALQVIHTDVHLSLGVTDLRDKPA 1146
Query 689 VGQSAQ--QILRAEANHSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMR 746
+ A+ Q+ +A F L Q +R ++ E+ + +L + ++HI D WS +L+
Sbjct 1147 AAKDAEWKQMAEEDAATPFRLDQWPLLRAMLIRLEEQESVLWLNVHHIISDGWSMDVLVN 1206
Query 747 ELIQAYTSRVDGKAPIWEKTPRQFHEYAMAQ----DDSALQAHIQYWMNTIGKIKKQQPL 802
EL + Y + + G+A P Q+ +YA+ Q D + ++YW N K+ +PL
Sbjct 1207 ELSEVYETLLKGEALPLAALPIQYRDYAVWQREKSQDDVWKEQLRYWKN---KLDGSEPL 1263
Query 803 LPAYRNDVDMPPPENNLDDVSGAAVEFNFTAIQVEQLYALARQYRSSLFYVVYAGLLLTT 862
LP + P + G + F ++L L RQ ++LF + A
Sbjct 1264 LP-----LPTDRPRAVVQSYRGDHLSFYVPGEVGQKLRELGRQEGATLFMTLLAAFKSFL 1318
Query 863 YYLGAGKKVLSGTSVACRQDPNYQDTLGYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKA 922
Y +L GT VA R ++ +G+F N+++ ++ + +L+ +V+ F A
Sbjct 1319 YRYTHANDILIGTPVAGRNRQEIENLIGFFVNMLVLRTDLSDDPTFVELLRRVRETAFDA 1378
Query 923 QEYADIPFAIVEDNIRAEGEEWTESPYEVYVQLHAQNALTGVFQLNSGDEIGFELIEPE- 981
D+PF + D ++ E + SP V Q TGV G+ + I P+
Sbjct 1379 FANEDVPFEKLVDELQIE-RSLSYSPL-FQVLFAVQGMSTGV---REGETLA---IAPDE 1430
Query 982 ---RDTAKFGLHFEVYEEPSSEKERLRVVINYRVNRYNEIQIQLIRQVAQQVLES 1033
T KF L + E + L+ V Y + ++ I+ + + +L++
Sbjct 1431 VTLNQTTKFDLTLTMIE---AADNGLKGVFEYSTDLFDRTTIERMAEHFGNLLQA 1482
Score = 58.5 bits (140), Expect = 1e-10
Identities = 97/428 (23%), Positives = 176/428 (41%), Gaps = 51/428 (12%)
Query 515 ITQLILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTA 574
+ Q + D + VL + DNFF+ GG SIL+ +++ + + G+ + F+ T
Sbjct 4606 VEQTLADIWCAVLRMDRIGIHDNFFELGGDSILSIQIVAR-ANKAGIHLTPKQLFDQQTI 4664
Query 575 LELSQCVEYLSDRVKDSSVADDNREIVAPLTLLQKAFMGFSNQGRDAMYNIPFAFRFSET 634
EL++ V S +V D+ + E+ PL +Q F Q +N + +E
Sbjct 4665 AELAK-VAGQSTKV-DAEQGNVTGEV--PLLPIQTWFFE-QKQPTPHHWNQSMLLQVNEP 4719
Query 635 VNEQAFYDAFLDILKRHHVMRSIFVQADQGEIFQTVIPMDRLNQHPWFWGSEHQVGQSAQ 694
+ E+ A +L H +R + AD G+ QT +D S Q A+
Sbjct 4720 LEEECLSQAVAQLLAHHDALRLRYTFAD-GQWKQTYADVDSEVPLQVEDLSMSPPAQQAR 4778
Query 695 QI--LRAEANHSFDLMQEFPIRVRFMK---DEQGQHILSMLLYHIAMDEWSSGILMRELI 749
+I L +A S DL ++V + D G+ L M+++H+A+D S IL+ +L
Sbjct 4779 KIEKLAQQAQASLDLQNGPLLKVVYFDLGYDRPGR--LLMVIHHLAVDGVSWRILIEDLQ 4836
Query 750 QAYTSRVDG-------KAPIWEKTPRQFHEYAMAQDDSALQAHIQYWMNTIGKIKKQQPL 802
AY G K ++ + H+YA ++ + YW+ ++
Sbjct 4837 TAYGQAEKGNKIQLPPKTTSYKAWAEKLHKYASSE---RMLVDQDYWLKAADELSGH--- 4890
Query 803 LPAYRNDVDMPPPENNLDDVSGAAVEFNFTAIQVEQLYALARQYRSSLFYVVYAGLLLTT 862
P P ++ + + A ++ E+ AL ++ S + V +LLT
Sbjct 4891 ----------PLPVHDWAENTEANGRMWTIHLEEEETDALLQKV-PSRYRVQINDILLTA 4939
Query 863 YYLGAGKKVLSGTSV-----------ACRQDPNYQDTLGYFTNVVMHYIQFNESLSIKDL 911
L GK +G S +D + T+G+FT++ IQ + S +D
Sbjct 4940 LALAYGK--WTGESALLVNLEGHGREELFEDVDLSRTVGWFTSMYPLLIQLEPNTSSEDA 4997
Query 912 VNQVQNNI 919
+ +V+ +
Sbjct 4998 LARVKEKL 5005
Score = 57.8 bits (138), Expect = 2e-10
Identities = 96/433 (22%), Positives = 180/433 (42%), Gaps = 45/433 (10%)
Query 505 SSVQPQVDASITQLILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIK 564
S V+PQ D + + + + +++VL + DNFF+ GG SIL +++ + Q GL +
Sbjct 2024 SFVEPQSD--VERKLAEIWQEVLGVETIGVHDNFFELGGDSILTIQIVSR-ANQAGLQLT 2080
Query 565 IADFFNAPTALELSQCVEYLSDRVKDSSVADDNREIVAPLTLLQKAFMGFSNQGRDA-MY 623
F+A T EL+ L ++ + PLT +Q F F R +
Sbjct 2081 PKHLFDAQTLAELAASAVVL-EKAPEMQAEQGIVTGELPLTPIQTWF--FEQDVRHVHHW 2137
Query 624 NIPFAFRFSETVNEQAFYDAFLDILKRHHVMRSIFV------QADQGEIF-QTVIPMDRL 676
N E ++ A AF + ++H +R F QA GEI + V+ + L
Sbjct 2138 NQSVMLAVREELDMTALTQAFAALPRQHDALRLRFQQVNGTWQAAHGEIADEDVLLVADL 2197
Query 677 NQHPWFWGSEHQVGQSAQQILRAEANHSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAM 736
+ P ++ + + E S D+ ++ P+ + L ++++H+ +
Sbjct 2198 SSVP------EAEREARMRHITDELQASLDI-EKGPLHRAAYFQLGAEQRLFIVIHHLVV 2250
Query 737 DEWSSGILMRELIQAYTSRVDGKAPIWEKTPRQFHEYAMAQDDSALQAHI-QYWMNTIGK 795
D S I++ +L AY G+ W + F +A A Q+ + +YW G
Sbjct 2251 DGVSWRIILEDLQTAYEQVKAGQKIAWPQKTTSFKSWAEELTTYAEQSAVDEYW---TGM 2307
Query 796 IKKQQPLLPAYRNDVDMPPPENNLDDVSGAAVEFNFTAIQVEQLYALARQ----YRSSLF 851
+Q LP VD P +N G AV+ + ++ AL ++ YR+ +
Sbjct 2308 DSEQACGLP-----VDHPQGKN----TEGLAVQVK-AKLSADETRALLQEVPAAYRTQIN 2357
Query 852 YVVYAGLLLTTYYLGAGKKVLSGTSVACRQDP-----NYQDTLGYFTNVVMHYIQFNESL 906
V+ + L T K+ L + ++P + T+G+FT++ ++ L
Sbjct 2358 DVLLSA-LTRTITDWTNKRALYVSVEGHGREPIVDGVDVSRTVGWFTSLYPVLLETEPDL 2416
Query 907 SIKDLVNQVQNNI 919
+ DL+ ++ +
Sbjct 2417 AWGDLLKSIKEQV 2429
Score = 54.3 bits (129), Expect = 2e-09
Identities = 79/359 (22%), Positives = 139/359 (39%), Gaps = 30/359 (8%)
Query 599 EIVAPLTLLQKAFMGFS---NQGRDAMYNIPFAFRFSETVNEQAFYDAFLDILKRHHVMR 655
E V LT LQ+ + S G D Y + A + E VN +AF A+ +++RH ++R
Sbjct 2582 ENVYTLTPLQEGMLFHSLYEQAGGD--YVVQLALKL-EHVNVEAFSAAWQKVVERHAILR 2638
Query 656 SIFVQADQGEIFQTVIPMDRLNQHPWFW----GSEHQVGQSAQQILRAEANHSFDLMQEF 711
+ F+ + + Q V + W +E + G Q L + FDL +
Sbjct 2639 TSFLWSGLEKPHQVVHAKVKTFVERLDWRHLTAAEQEAG--LQTYLEQDRKRGFDLARPP 2696
Query 712 PIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTSRVDGKAPIWEKTPRQFH 771
+R ++ + +H+ +D WS+ I+ ++ Y + GK P F
Sbjct 2697 LMRWTLIRLDASTFQFVWSFHHMLLDGWSTPIVFQDWQAFYAAASHGKEASLPAIP-PFS 2755
Query 772 EYAMAQDDSALQAHIQYWMNTIGKIKKQQPLLPAYRNDVDMPPPENNLDDVSGAAVEFNF 831
Y L+ QYW + + PL P E A +
Sbjct 2756 AYIAWLKRQNLEEAQQYWRDYLQGFGVPTPLGMGKSGGSAGQPKEY-------ADHKLLL 2808
Query 832 TAIQVEQLYALARQYRSSLFYVVY-AGLLLTTYYLGAGKKVLSGTSVACRQD-PNYQDTL 889
+ L A AR+++ +L VV A L+ Y G + V T++ D P+ + +
Sbjct 2809 SERATANLLAFARKHQLTLNTVVQGAWALILARYAGEAEVVFGTTNLGRPTDLPDAEAMV 2868
Query 890 GYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQEYADIPFAIVEDNIRAEGEEWTESP 948
G F N + + F E ++ D + +Q + ++Y P + + W+E P
Sbjct 2869 GLFINTLPVRVLFPEQTTVIDWLQSLQQAQSEMRQYEFTPLVDI--------QSWSEVP 2919
Score = 53.1 bits (126), Expect = 5e-09
Identities = 93/445 (21%), Positives = 180/445 (40%), Gaps = 56/445 (13%)
Query 35 EHYTENQIINIEKNG-VQLSFTEERAWMLHQQDPLASSGPFILAFRLSGEIEISRLSNAI 93
++ TE Q++ + + + LSF ++R W L + P ++ A RL G+++I+ ++
Sbjct 3617 QNETEAQMLPVSREAHLPLSFAQQRLWFLDRLMPDSTLYNIPSAVRLLGDLDIAAWEKSL 3676
Query 94 QKLYEGDSNLNLRY-DLDDEGILNKYHDEHTPFEMNIHVV------KSEQEAVQYLLSWI 146
Q L + +L + D+D E + H+ + ++V+ E+EA + L+ +
Sbjct 3677 QVLIQRHESLRTTFGDVDGEAV----QVIHSRLDGKLNVIDLRGMPADEREAEAHRLAGL 3732
Query 147 Q--KPINLAKAPAIQFTLLPQSHHEVILGILGHHILLDD-------SAWQPIFAQLSQNY 197
+ P +L++ P ++ TL+ + E + HHI+ D + ++ +
Sbjct 3733 EAATPFDLSQGPLLRTTLIRLAEQECVFLFNLHHIIFDGWSIGIFLKEMRALYEAFVREE 3792
Query 198 AQLDGVLTASNSHIELSSK--IPAKVLVNSQNALQYWKTIFPTGLNQLDWPKFCRAPNVQ 255
A +T + + + + +VL L YWK L P P VQ
Sbjct 3793 APELAEITVQYADYAVWQRKWLEGEVLAEQ---LAYWKEKLSGAEPLLALPTDQPRPAVQ 3849
Query 256 ASIIQYGQNTIFDYEQKAVRCSSSIPLKGLKQLSERAQASIFHTVVAQFGGYLNHLFGTQ 315
D ++ S + K L +LS+ A++F T++A F L G +
Sbjct 3850 T----------HDGAMHTIKLSGELYAK-LNKLSQEEGATLFMTLLAAFQVLLYRYSGQE 3898
Query 316 SIDLFVPIVEQYEASSLSQIRSSSNILPIRILRPEYSEQESNIENKEKESIVNVRNQILQ 375
I + P+ + + I N L +LR + S E +E + VR +
Sbjct 3899 DILVGSPVAGRNRQETEPLIGFFINTL---VLRTDLSG-----EPTFRELLARVRETAFE 3950
Query 376 GMVH-NISIEQILSATKTKRNTIPNVLVTQFIDGSQFLKLEQVETSTLIIPPIHSD---- 430
H ++ E+++ + +R+ + L Q + Q +L E + + + D
Sbjct 3951 AYAHQDLPFEKLVDELELERSLSYSPLF-QVMFVLQNFQLNLDEKAGIRVADFEMDKHLV 4009
Query 431 ---YDLTLAFQIKADEIH--FELTT 450
YDLTL K + + FE T
Sbjct 4010 TSKYDLTLTMAEKQNGLFATFEYNT 4034
Score = 48.5 bits (114), Expect = 1e-07
Identities = 66/345 (19%), Positives = 132/345 (38%), Gaps = 25/345 (7%)
Query 601 VAPLTLLQKAFMGFS--NQGRDAMYNIPFAFRFSETVNEQAFYDAFLDILKRHHVMRSIF 658
+ PLT +Q+ + S ++G ++ + F ++ + +++RH ++R++F
Sbjct 9 IYPLTPMQEGMLFHSLLDEGSESYFE-QMRFTIKGLIDPAILEQSLNALIERHDILRTVF 67
Query 659 VQADQGEIFQTVIP--MDRLNQHPWFWGSEHQVGQSAQQILRAEANHSFDLMQEFPIRVR 716
+ + Q V+ ++ SE + + + + SFDL ++ IR+
Sbjct 68 LLEKVQKPRQIVLRERKTKVQVLDITHLSEGEQAAYLEDFAQKDRQASFDLAKDVLIRLT 127
Query 717 FMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTSRVDGKAPIWEKTPRQFHEYAMA 776
++ H L +HI +D W I++ + Q Y R G P+ + Y
Sbjct 128 LVRTSADTHTLFWSHHHILLDGWCIPIVLNDFFQIYQQR-KGGLPVELGPVYPYSTYISW 186
Query 777 QDDSALQAHIQYWMNTIGKIKKQQPLLPAYRNDVDMPPPENNLDDVSGAAVEFNFTAIQV 836
+ + W I + + + A + F
Sbjct 187 LGEQDAEEAKASWAEYISGYE-----------PTSFIHKQGGKNSYRQAELVFAIEQGLT 235
Query 837 EQLYALARQYR---SSLFYVVYAGLLLTTYYLGAGKKVLSGTSVACRQD--PNYQDTLGY 891
+ L LA+Q ++LF ++ GL+L + V+ G+ V+ R PN + +G
Sbjct 236 DSLNKLAKQLHVTLNNLFRAIW-GLMLQRQC--NTEDVVFGSVVSGRPSHLPNVEQMVGL 292
Query 892 FTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQEYADIPFAIVEDN 936
F N V +Q + +LV QVQ +Y + A ++ N
Sbjct 293 FINTVPIRVQAGAEQTFSELVKQVQQEALSLAKYHYLSLADIQGN 337
Score = 43.5 bits (101), Expect = 4e-06
Identities = 92/467 (20%), Positives = 185/467 (40%), Gaps = 53/467 (11%)
Query 52 LSFTEERAWMLHQQDPLASSGPFILAFRLSGEIEISRLSNAIQKLYEGDSNLNLRY-DLD 110
LS+ ++R W L + P ++ + FRL G ++ L A+ ++ + +L + D+D
Sbjct 1062 LSYAQQRLWFLDRLIPDSAMYNIPVGFRLRGTVDELVLERALNEIIQRHESLRTTFVDVD 1121
Query 111 DEGILNKYHDEHTPFEMNIHVVKSEQEAVQYLLSWIQ-------KPINLAKAPAIQFTLL 163
+ + D H + + ++ + A + W Q P L + P ++ L+
Sbjct 1122 GRALQVIHTDVH--LSLGVTDLRDKPAAAKD-AEWKQMAEEDAATPFRLDQWPLLRAMLI 1178
Query 164 PQSHHEVILGILGHHILLDDSAWQPIFAQLSQNYAQLDGVLTASNSHIELSSKIPAKVLV 223
E +L + HHI+ D + + +LS+ Y L + + + + A V
Sbjct 1179 RLEEQESVLWLNVHHIISDGWSMDVLVNELSEVYETLLKGEALPLAALPIQYRDYA-VWQ 1237
Query 224 NSQNALQYWKTIFPTGLNQLDW--PKFCRAPNVQASIIQ-YGQNTIFDYEQKAVRCSSSI 280
++ WK N+LD P + +++Q Y + + Y V
Sbjct 1238 REKSQDDVWKEQLRYWKNKLDGSEPLLPLPTDRPRAVVQSYRGDHLSFYVPGEVG----- 1292
Query 281 PLKGLKQLSERAQASIFHTVVAQFGGYLNHLFGTQSIDLFVPIVEQYEASSLSQIRSSSN 340
+ L++L + A++F T++A F +L I + P+ + + I N
Sbjct 1293 --QKLRELGRQEGATLFMTLLAAFKSFLYRYTHANDILIGTPVAGRNRQEIENLIGFFVN 1350
Query 341 ILPIRILRPEYSEQESNIENKEKESIVNVRNQILQGMVH-NISIEQILSATKTKRNTIPN 399
+L +LR + S+ + + E + VR + ++ E+++ + +R+ +
Sbjct 1351 ML---VLRTDLSDDPTFV-----ELLRRVRETAFDAFANEDVPFEKLVDELQIERSLSYS 1402
Query 400 VLVTQFIDGSQFLKLEQVETSTLIIPPIH------SDYDLTLAFQIKADE---------- 443
L Q + Q + E TL I P + +DLTL AD
Sbjct 1403 PLF-QVLFAVQGMSTGVREGETLAIAPDEVTLNQTTKFDLTLTMIEAADNGLKGVFEYST 1461
Query 444 IHFELTTGEKLSKKIGLLLLEQWIEFLHLDAQQRLEEAAIFAFGHQA 490
F+ TT E++++ G LL + + D Q++ E + Q+
Sbjct 1462 DLFDRTTIERMAEHFGNLL-----QAIAADPGQKIVELPLLGGAEQS 1503
Score = 34.3 bits (77), Expect = 0.003
Identities = 28/150 (19%), Positives = 56/150 (37%), Gaps = 6/150 (4%)
Query 58 RAWMLHQQDPLASSGPFILAFRLSGEIEISRLSNAIQKLYEGDSNLNLRYDLDDEGILNK 117
+ W Q+ P + +++ +E LS A+ +L L LRY D
Sbjct 4694 QTWFFEQKQPTPHHWNQSMLLQVNEPLEEECLSQAVAQLLAHHDALRLRYTFADGQWKQT 4753
Query 118 YHDEHTPFEMNIHVVKSEQEA-----VQYLLSWIQKPINLAKAPAIQFTLLPQSHHEV-I 171
Y D + + + + A ++ L Q ++L P ++ +
Sbjct 4754 YADVDSEVPLQVEDLSMSPPAQQARKIEKLAQQAQASLDLQNGPLLKVVYFDLGYDRPGR 4813
Query 172 LGILGHHILLDDSAWQPIFAQLSQNYAQLD 201
L ++ HH+ +D +W+ + L Y Q +
Sbjct 4814 LLMVIHHLAVDGVSWRILIEDLQTAYGQAE 4843
Score = 32.7 bits (73), Expect = 0.008
Identities = 42/193 (22%), Positives = 81/193 (42%), Gaps = 14/193 (7%)
Query 15 LFESK-LQDIGLSERISTEAVEHYTENQIINIEKNGVQLSFTEERAWMLHQQDPLASSGP 73
LF+++ L ++ S + +A E E I+ E L T + W Q
Sbjct 2084 LFDAQTLAELAASAVVLEKAPEMQAEQGIVTGE-----LPLTPIQTWFFEQDVRHVHHWN 2138
Query 74 FILAFRLSGEIEISRLSNAIQKLYEGDSNLNLRYDLDDEGILNKYHDEHTPFEMNI---- 129
+ + E++++ L+ A L L LR+ G H E ++ +
Sbjct 2139 QSVMLAVREELDMTALTQAFAALPRQHDALRLRFQ-QVNGTWQAAHGEIADEDVLLVADL 2197
Query 130 -HVVKSEQEA-VQYLLSWIQKPINLAKAPAIQFTLLPQSHHEVILGILGHHILLDDSAWQ 187
V ++E+EA ++++ +Q +++ K P + Q E L I+ HH+++D +W+
Sbjct 2198 SSVPEAEREARMRHITDELQASLDIEKGPLHRAAYF-QLGAEQRLFIVIHHLVVDGVSWR 2256
Query 188 PIFAQLSQNYAQL 200
I L Y Q+
Sbjct 2257 IILEDLQTAYEQV 2269
Score = 28.5 bits (62), Expect = 0.15
Identities = 26/75 (35%), Positives = 31/75 (41%), Gaps = 4/75 (5%)
Query 134 SEQEAVQYLLSWIQKP----INLAKAPAIQFTLLPQSHHEVILGILGHHILLDDSAWQPI 189
SE E YL + QK +LAK I+ TL+ S L HHILLD +
Sbjct 96 SEGEQAAYLEDFAQKDRQASFDLAKDVLIRLTLVRTSADTHTLFWSHHHILLDGWCIPIV 155
Query 190 FAQLSQNYAQLDGVL 204
Q Y Q G L
Sbjct 156 LNDFFQIYQQRKGGL 170
>Q70LM5 ATP-dependent valine adenylase / ATP-dependent D-valine
adenylase / Valine racemase [ATP-hydrolyzing] / ATP-dependent
tryptophan adenylase / ATP-dependent tryptophan/phenylalanine/tyrosine
adenylase [Brevibacillus parabrevis]
Length=7756
Score = 146 bits (369), Expect = 1e-37
Identities = 133/535 (25%), Positives = 232/535 (43%), Gaps = 36/535 (7%)
Query 517 QLILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTA-- 574
+LI + QVL + DNFF+ GGHS+LATRVI +L+ G+ + F PT
Sbjct 984 ELIASIWSQVLGVEKVGIHDNFFELGGHSLLATRVISRLREVFGVEQSVRSIFEHPTIDA 1043
Query 575 -LELSQCVEYLSDRVKDSS--VADDNREIVAPLTLLQKAFMGFSNQGRD-AMYNIPFAFR 630
E + ++ DSS + R+ PL+ Q+ F D MYNIPFA R
Sbjct 1044 WSEQTAALQLGGPGTDDSSTQIQPVPRDGALPLSFAQQRLWFFDQLMPDNPMYNIPFALR 1103
Query 631 FSETVNEQAFYDAFLDILKRHHVMRSIFVQADQGEIFQTVIP-MD-RLNQHPWFWGSEHQ 688
++ A+ + I+ RH +R+ F D G+ Q + P +D +L+ S +
Sbjct 1104 LQGELDVAAWEKSLQAIIARHESLRTTFTDID-GQAVQVIHPQLDWKLDTVDLRDRSSEE 1162
Query 689 VGQSAQQILRAEANHSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMREL 748
Q++ ++ +A FDL Q +R ++ E+ H+ + ++HI D WS G+ +REL
Sbjct 1163 KQQASARLAADDAARPFDLRQGPLMRATMIRTEEQAHVFLINMHHIVSDGWSVGVFLREL 1222
Query 749 IQAYTSRVDGKAPIWEKTPRQFHEYAMAQ----DDSALQAHIQYWMNTIGKIKKQQPLLP 804
Y + G+ P P Q+ ++A Q + L+ + YW +G +PLL
Sbjct 1223 FAHYEAYSKGEVPQLAPMPIQYADFAAWQREWLEGEVLEQQVAYWKEKLG---GAEPLLA 1279
Query 805 AYRNDVDMPPPENNLDDVSGAAVEFNFTAIQVEQLYALARQYRSSLFYVVYAGLLLTTYY 864
D P P L GA +F+ + +L L+++ + L + + Y
Sbjct 1280 L---PTDRPRPA--LQSYEGATYTTSFSHDLLAKLKKLSKEAQHDLVHDIARRFPNVLYR 1334
Query 865 LGAGKKVLSGTSVACRQDPNYQDTLGYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQE 924
+ ++ G+ VA R + +G+F N + + L +L+ +V+ A
Sbjct 1335 YSGQEDIVVGSPVAGRNRQETEKLIGFFVNTLALRTSLSGDLPFTELLARVRETALAAYA 1394
Query 925 YADIPFAIVEDNIRAEGEEWTESPYEVYVQLHAQNALTGVFQLNSGDEIGFEL----IEP 980
+ D+PF + D ++ E ++V L QN F L + G + E
Sbjct 1395 HQDVPFEKLVDELQLERSLSYSQLFQVMFVL--QN-----FPLEDVETAGLHVAPVDTES 1447
Query 981 ERDTAKFGLHFEVYEEPSSEKERLRVVINYRVNRYNEIQIQLIRQVAQQVLESFI 1035
T+KF L + E +++ L Y + ++ I+ + + Q +L S +
Sbjct 1448 HLTTSKFDLTLTMRE----KEDTLVAAFEYSTDLFDRTTIERMAEHLQHLLASIV 1498
Score = 141 bits (356), Expect = 5e-36
Identities = 134/601 (22%), Positives = 250/601 (42%), Gaps = 37/601 (6%)
Query 466 WIEFLHLDAQQRLEEAAIFAFGHQASPYGSDQEHWAQPTSSVQPQVDASITQLILDEFKQ 525
W+E + L +++ A+ A YG H + V P+ I +++ + + Q
Sbjct 6108 WLEKIPLTVNGKVDRRAL-----PAPDYG----HAETGKAYVAPR--KPIEEIVANIWAQ 6156
Query 526 VLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTALELSQCVEYLS 585
VL + D+FF+ GGHS+LAT+ + +L+ G+ + + F P +S+ + L
Sbjct 6157 VLSVERVGVYDDFFELGGHSLLATQAVSRLKEAFGVNVPLRTLFEHPDVAGMSEKLAGLL 6216
Query 586 DR---VKDSSVADDNREIVAPLTLLQKAFMGFSNQGRD-AMYNIPFAFRFSETVNEQAFY 641
+ V + R+ PL+ Q+ D A+YNIP A R +N +A+
Sbjct 6217 EEQSGVTSIPLVPVPRDKQLPLSFAQQRLWFLDRLMPDSALYNIPSAVRIQGQLNIRAWE 6276
Query 642 DAFLDILKRHHVMRSIFVQADQGEIFQTVIPMD--RLNQHPWFWGSEHQVGQSAQQILRA 699
+ I++RH +R+ F GE Q + M RL + + + + Q++ +A
Sbjct 6277 RSLQTIIERHESLRTTFTDIG-GEAVQVIHEMMEWRLVEIDLRDLPDEEREAAVQRLEKA 6335
Query 700 EANHSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTSRVDGK 759
EA+ F+L +R ++ + + + ++HI D WS I M EL Y + G
Sbjct 6336 EASQPFNLRTGPLLRATLIQTGEEDFVFLLNMHHIVSDGWSMSIFMGELATIYEALSKGD 6395
Query 760 APIWEKTPRQFHEYAMAQDD----SALQAHIQYWMNTIGKIKKQQPLLPAYRNDVDMPPP 815
P + P Q+ ++A Q D L+ + YW +G + P D P P
Sbjct 6396 TPQLAEMPLQYADFAAWQRDWLQGEVLEQQLAYWREKLGAAE------PMLALPTDRPRP 6449
Query 816 ENNLDDVSGAAVEFNFTAIQVEQLYALARQYRSSLFYVVYAGLLLTTYYLGAGKKVLSGT 875
+ GA F E+L+AL+RQ ++LF + A Y ++ G+
Sbjct 6450 A--VQTHHGALYTTAFPLALTEKLHALSRQEGATLFMTLLAAFQTLLYRYSGQDDIIVGS 6507
Query 876 SVACRQDPNYQDTLGYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQEYADIPFAIVED 935
VA R + +G+F N + + + + ++L+ +V++ +A + D+PF + D
Sbjct 6508 PVAGRNKQETESMIGFFINTLAMRTDMSGAPTFRELLARVRDTALEAYTHQDLPFEKLID 6567
Query 936 NIRAEGEEWTESPYEVYVQLHAQNALTGVFQLNSGDEIGFELIEPERDTAKFGLHFEVYE 995
+ E ++V L LT F+ G E++ E +++
Sbjct 6568 ELELERSLSYSPLFQVMFALQNFQMLTREFE-------GIEIVPFESKNEAVMSKYDISL 6620
Query 996 EPSSEKERLRVVINYRVNRYNEIQIQLIRQVAQQVLESFIHIDTQSEECTQIDVMEIRHQ 1055
+ + L +Y + ++ I + Q+LE + S + + + R Q
Sbjct 6621 TMAETQNGLVATFDYNTDLFDHSTIVRMVNHFHQLLEGIVARPDSSIQALPLLATDEREQ 6680
Query 1056 L 1056
L
Sbjct 6681 L 6681
Score = 138 bits (347), Expect = 6e-35
Identities = 106/437 (24%), Positives = 196/437 (45%), Gaps = 25/437 (6%)
Query 517 QLILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTALE 576
+++ + + Q+L + D+FF+ GGHS+LAT+ I +L+ G+ + + F+ PT
Sbjct 3564 EMVANIWAQLLSVEKIGVHDDFFERGGHSLLATQAISRLRQAFGVELPLRMLFDHPTTAA 3623
Query 577 LSQCVEYL---SDRVKDSSVADDNREIVAPLTLLQKAFMGFSNQGRDA-MYNIPFAFRFS 632
+S + L ++ + R+ PL+ Q+ ++ +YNIP A R
Sbjct 3624 ISTQIASLLQGETALRSQPIVPVPRDQHVPLSFAQQRLWFLDRLIPNSFLYNIPSAARLH 3683
Query 633 ETVNEQAFYDAFLDILKRHHVMRSIFVQADQGEIFQTVIP-----MDRLNQHPWFWGSEH 687
++ +A+ + +++RH +R+ F D GE Q + P + R++ W +E
Sbjct 3684 GELDVEAWERSLKLLIQRHESLRTTFSDRD-GEAVQIIHPAIEWSLGRVDLREW---AEA 3739
Query 688 QVGQSAQQILRAEANHSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRE 747
+ A Q+ +A FDL + +R + Q +++ + L+HI D WS + M E
Sbjct 3740 EREAKALQLAIEDAKRPFDLERGPLLRASLLVMAQQEYVFLLNLHHIVADGWSMNVFMEE 3799
Query 748 LIQAYTSRVDGKAPIWEKTPRQFHEYAMAQDD----SALQAHIQYWMNTIGKIKKQQPLL 803
L+ Y + G+ P + P Q+ +YA Q D L+ + YW K+ +PLL
Sbjct 3800 LVTIYEALSAGETPQLAELPLQYADYAAWQRDWLQGDVLEQQLAYWK---AKVGGAEPLL 3856
Query 804 PAYRNDVDMPPPENNLDDVSGAAVEFNFTAIQVEQLYALARQYRSSLFYVVYAGLLLTTY 863
D P P + GA A ++ L L+R+ S+LF + A Y
Sbjct 3857 AL---PTDRPRPA--VQSHKGAMHTITLPAERLAALKTLSREEGSTLFMTLLAAFQTLLY 3911
Query 864 YLGAGKKVLSGTSVACRQDPNYQDTLGYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQ 923
++ G+ VA R + +G+F N + + + +DL+ +V+ +A
Sbjct 3912 RYSGQSDIVVGSPVAGRNRQETESLIGFFINTLAMRTDLSGEPTFRDLLGKVRETALEAY 3971
Query 924 EYADIPFAIVEDNIRAE 940
+ D+PF + D + E
Sbjct 3972 AHQDLPFEKLVDELELE 3988
Score = 67.8 bits (164), Expect = 2e-13
Identities = 72/328 (22%), Positives = 132/328 (40%), Gaps = 12/328 (4%)
Query 604 LTLLQKAFMGFSNQGRDAMYNIPFAFRFSETVNEQAFYDAFLDILKRHHVMRSIFVQADQ 663
LT LQ+ + S + Y I + ++ F A+ +++RH ++R+ F+ +
Sbjct 13 LTPLQEGMLFHSLYSEGSAYMIQTTAILTGELDIVPFEKAWKKVIQRHSILRTGFIWEET 72
Query 664 GEIFQTV---IPMDRLNQHPWF-WGSEHQVGQSAQQILRAEANHSFDLMQEFPIRVRFMK 719
+ Q V +P + Q W +GS+ Q A L+ E FDL + +RV +K
Sbjct 73 EKPLQAVFESVPFS-IRQKDWSSYGSDEQESMLAA-FLQNEKAAGFDLSEAPLMRVTIIK 130
Query 720 DEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTSRVDGKAPIWEKTPRQFHEYAMAQDD 779
+ H L +H+ +D WSS I+ +E++ Y + GK + R F +Y
Sbjct 131 LGEAVHRLIWSFHHLLLDGWSSPIVFQEVLDFYEAYRQGK-DLRLPQARPFKDYVSWLRR 189
Query 780 SALQAHIQYWMNTIGKIKKQQPLLPAYRNDVDMPPPENNLDDVSGAAVEFNFTAIQVEQL 839
A Q+W +G ++ P+ + L+ G A T + L
Sbjct 190 QDKTASEQFWREFLGPMENPTPI--PFETHAKRTAGHEGLEKQIGEATR-ALTGQVTKAL 246
Query 840 YALARQYRSSLFYVVYAGLLLTTYYLGAGKKVLSGTSVACRQD--PNYQDTLGYFTNVVM 897
LAR + ++ +V + L + V+ G + + R P + +G F N +
Sbjct 247 AKLARTNKVTVNTIVQGAWAILLSRLSGEENVVYGVTGSGRPSDLPGVEQMVGMFINTLP 306
Query 898 HYIQFNESLSIKDLVNQVQNNIFKAQEY 925
+ S+ D +Q K ++Y
Sbjct 307 MKAKIEPEQSLADWFKALQEQQSKVRQY 334
Score = 59.7 bits (143), Expect = 5e-11
Identities = 78/356 (22%), Positives = 145/356 (41%), Gaps = 23/356 (6%)
Query 584 LSDRVKDSSVADDNR-EIVAPLTLLQKAFMGFS---NQGRDAMYNIPFAFRFSETVNEQA 639
L R D+ V D E V PLT LQ+ + S + G D Y + F+ V
Sbjct 2590 LDQRAIDNYVGRDRSIENVYPLTPLQEGMLFHSLYEHAGGD--YVVQFSMTMHH-VEVDV 2646
Query 640 FYDAFLDILKRHHVMRSIFVQADQGEIFQTVIPMDRL--NQHPWFWGSEHQVGQSAQQIL 697
F A+ ++ RH ++R+ F+ Q V ++ ++ W Q L
Sbjct 2647 FQQAWQKVVDRHSILRTSFIWDGVSTPHQIVRKHVQVVVDEQDWRHVPADQQKAEWDAFL 2706
Query 698 RAEANHSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTSRVD 757
+ SF + + +R ++ + +H+ +D WS ++M++ AY + D
Sbjct 2707 EEDRKRSFAITEPPLMRWTLLRISDTAYRFIWSFHHVLLDGWSVPLVMKDWFAAYMALAD 2766
Query 758 GKAPIWEKTPRQFHEYAMAQDDSALQAHIQYWMNTIGKIKKQQPLLPAYRNDVDMPPPEN 817
GK I F +Y LQA ++W N + I P + V
Sbjct 2767 GK-DIQFGAVHPFSQYVAWIQRQDLQAAERFWRNHLKGI--YAPTQVNFGQTVQPVGETK 2823
Query 818 NLDDVSGAAVEFNFTAIQVEQLYALARQYRSSLFYVVYA--GLLLTTYYLGAGKKVLSGT 875
+ D+ S F+A + +L A ARQ++ +L +V + ++L TY A V+ G
Sbjct 2824 SYDERS-----IRFSAERTRELQAFARQHQVTLNTLVQSAWAMILGTYSKEA--DVVFGA 2876
Query 876 SVACRQD--PNYQDTLGYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQEYADIP 929
+ + R P ++ +G F N + + + +++ + ++Q + ++Y P
Sbjct 2877 TGSGRPADLPGVENMVGLFINTLPIRVTLDPGKKVREWLRELQELQVELRQYEYTP 2932
Score = 57.4 bits (137), Expect = 3e-10
Identities = 92/456 (20%), Positives = 174/456 (38%), Gaps = 58/456 (13%)
Query 599 EIVAPLTLLQKAFMGFS---NQGRDAMYNIPFAFRFSETVNEQAFYDAFLDILKRHHVMR 655
E V PL+ LQ + S +G D + + E ++ +AF A+ ++ RH ++R
Sbjct 5184 ENVYPLSPLQGGMLFHSLYEQEGGDYVVQLAMTV---EGLDVEAFEQAWQKVVDRHSILR 5240
Query 656 SIFV--------QADQGEIFQTVIPMDRLNQHPWFWGSEHQVGQSAQQILRAEANHSFDL 707
+ F+ Q + ++ V +D + P Q + L A+ SF++
Sbjct 5241 TSFIWEGLTEPHQVVRKQVKACVEKIDLRHLTP------DQQKAELSEYLAADRRRSFEI 5294
Query 708 MQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTSRVDGK--APIWEK 765
+R + + + + +H+ +D WS I++++ AY S +GK A + +
Sbjct 5295 AVAPLMRWTLFRLSESAYRFTWSFHHVLLDGWSIPIVLKDWFSAYLSLAEGKEVAHSFVQ 5354
Query 766 TPRQFHEYAMAQDDSALQAHIQYWMNTIGKIKKQQPLLPAYRNDVDMPPPENNLDDVSGA 825
+ E+ QD LQA Q+W + + PL P+ +
Sbjct 5355 PFAHYVEWVQRQD---LQAAEQFWREQLAGFYEPTPLAMGNSTGGRADLPKGYEEQ---- 5407
Query 826 AVEFNFTAIQVEQLYALARQYRSSLFYVVY-AGLLLTTYYLGAGKKVLSGTSVACRQD-P 883
E +L A R ++ +L +V A L+ Y G V T D P
Sbjct 5408 --EIRLAKDATARLQAFVRTHQLTLNTLVQGAWALMLGRYGGTDDVVFGATGSGRPADLP 5465
Query 884 NYQDTLGYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQEYADIPFAIVEDNIRAEGEE 943
+ +G F N + + + + S+++ + +Q + ++Y P ++
Sbjct 5466 GVESMVGLFINTLPIRVALDANQSVREWLRGMQEQQVELRQYEYTPLVDIQG-------- 5517
Query 944 WTESPYEVYVQLHAQNALTGVFQLNSGDEIGFELIEPERDTAKFGLHFEVYEEPS----- 998
W+E + AL + IG E ++ E+ + E E+ +
Sbjct 5518 WSE--------MTRNTALFESIFIFENYPIG-ESVKDEQHQLRLS-DVETIEQTNYPLTV 5567
Query 999 --SEKERLRVVINYRVNRYNEIQIQLIRQVAQQVLE 1032
E L V I Y NR+ QI+ + Q Q+L+
Sbjct 5568 VCGPGEELIVKIKYEQNRFAPEQIERVLQQMSQLLQ 5603
Score = 55.8 bits (133), Expect = 8e-10
Identities = 114/554 (21%), Positives = 215/554 (39%), Gaps = 71/554 (13%)
Query 519 ILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTALELS 578
+ D +K VL ++ DNFF+ GG SIL+ +++ + Q G+ + F T EL
Sbjct 2051 LADIWKTVLGVADVGIHDNFFELGGDSILSIQIVAR-ANQLGIRLTPKQLFENQTIAELL 2109
Query 579 QCVEYLSDRVKDSSVADDNREIV----APLTLLQKAFMGFSNQGRDAMYNIPFAFRFSET 634
+ V +D + +N + + PLT +QK F ++Q +N +
Sbjct 2110 RVV---ADSSQLPHTKWENEQGIVTGNVPLTPIQKWFFA-ADQPSLHHWNQSLLLTVQQP 2165
Query 635 VNEQAFYDAFLDILKRHHVMRSIFVQADQGEIFQTVIPMDRLNQHPWF-------WGSEH 687
V+ A +L H +R F D Q M+ L H F ++
Sbjct 2166 VDVSVLERAIASLLSHHDALRMSFSFVDGAWTQQ----MNGLGDHTPFRCVDLSDLSTQE 2221
Query 688 QVGQSAQQILRAEANHSFDLMQEFPIR-VRFMKDEQGQHILSMLLYHIAMDEWSSGILMR 746
Q + + + +E S ++ + ++ V F EQ L ++++H+ +D S IL+
Sbjct 2222 QEQAARLEEIASEVQASLNIAEGNVVQAVYFNLGEQKAGRLLLVVHHLVVDGVSWRILLE 2281
Query 747 ELIQAYTSRVD-------GKAPIWEKTPRQFHEYAMAQDDSALQAHIQYWMNTIGKIKKQ 799
+L AY + K ++ + +YA D AL+ YW+ +
Sbjct 2282 DLQHAYEQLANHADVSFPAKTTSFKMWAEKLADYA---DSDALEQEKAYWLQ---QSSGG 2335
Query 800 QPLLPAYRNDVDMPPPENNLDDVSGAAVEFNFTAIQVEQ-LYALARQYRSSLFYVVYAGL 858
PL VD P N + + V + A + L+ YR + V+ A L
Sbjct 2336 SPL------PVDHPYEPNENTEAAAKQVTLSLRADETRALLHETLTAYRLQINDVLLAAL 2389
Query 859 -----------LLTTYYLGAGK-KVLSGTSVACRQDPNYQDTLGYFTNVVMHYIQFNESL 906
L + G G+ +++ G ++ T+G+FT++ + F++S
Sbjct 2390 AKAMQRWTGQKTLHVHLEGHGREEIIEGADLS--------RTVGWFTSMYPVQLDFDQSK 2441
Query 907 SIKDLVNQVQNNIFKAQEYADIPFAIVEDNIRAEGEEWTESPYEVYVQLHAQNALTGVFQ 966
++ V+ + + I + I++ + +EW E + Y + G F
Sbjct 2442 PWGHVLKAVKEQLRHIPQ-KGIGYGILQ--YLSNDDEWKEQ-LQAYTKPEISFNYLGQFD 2497
Query 967 LNSGDEIGFELIEPER--DTAKFGLHFEVYEEPSS-EKERLRVVINYRVNRYNEIQIQLI 1023
F + E R + A + + + S+ E+L + Y N +N+ + I
Sbjct 2498 QVVSAGAKFAMAEESRGANIAADAIRAHLIDVNSAISGEQLHITWMYNANIHNQ---ETI 2554
Query 1024 RQVAQQVLESFIHI 1037
+A+ +ES I
Sbjct 2555 EALARDYMESLREI 2568
Score = 54.7 bits (130), Expect = 2e-09
Identities = 93/462 (20%), Positives = 179/462 (39%), Gaps = 65/462 (14%)
Query 38 TENQIINIEKNG-VQLSFTEERAWMLHQQDPLASSGPFILAFRLSGEIEISRLSNAIQKL 96
+ QI + ++G + LSF ++R W Q P A RL GE++++ ++Q +
Sbjct 1061 SSTQIQPVPRDGALPLSFAQQRLWFFDQLMPDNPMYNIPFALRLQGELDVAAWEKSLQAI 1120
Query 97 YEGDSNLNLRY-DLDDEGILNKYHDEHTPFEMNIHVV--------KSEQEAVQYLLSWIQ 147
+L + D+D + + H + + V + +Q + +
Sbjct 1121 IARHESLRTTFTDIDGQAV----QVIHPQLDWKLDTVDLRDRSSEEKQQASARLAADDAA 1176
Query 148 KPINLAKAPAIQFTLLPQSHHEVILGILGHHILLDDSAWQPIFAQLSQNY-----AQLDG 202
+P +L + P ++ T++ + I HHI+ D + +L +Y ++
Sbjct 1177 RPFDLRQGPLMRATMIRTEEQAHVFLINMHHIVSDGWSVGVFLRELFAHYEAYSKGEVPQ 1236
Query 203 VLTASNSHIELSS----KIPAKVLVNSQNALQYWKTIFPTGLNQLDWPKFCRAPNVQASI 258
+ + + ++ + +VL + + YWK L P P +Q+
Sbjct 1237 LAPMPIQYADFAAWQREWLEGEVL---EQQVAYWKEKLGGAEPLLALPTDRPRPALQS-- 1291
Query 259 IQYGQNTIFDYEQKAVRCSSSIPLKG-LKQLSERAQASIFHTVVAQFGGYLNHLFGTQSI 317
YE S S L LK+LS+ AQ + H + +F L G + I
Sbjct 1292 ----------YEGATYTTSFSHDLLAKLKKLSKEAQHDLVHDIARRFPNVLYRYSGQEDI 1341
Query 318 DLFVPIVEQYEASSLSQIRSSSNILPIRILRPEYSEQESNIENKEKESIVNVRNQILQGM 377
+ P+ + + I N L +R + + E + VR L
Sbjct 1342 VVGSPVAGRNRQETEKLIGFFVNTLALR--------TSLSGDLPFTELLARVRETALAAY 1393
Query 378 VH-NISIEQILSATKTKRNTIPNVLVTQFIDGSQFLKLEQVETSTLIIPPIH-------S 429
H ++ E+++ + +R+ + L Q + Q LE VET+ L + P+ S
Sbjct 1394 AHQDVPFEKLVDELQLERSLSYSQLF-QVMFVLQNFPLEDVETAGLHVAPVDTESHLTTS 1452
Query 430 DYDLTLAFQIKADEI---------HFELTTGEKLSKKIGLLL 462
+DLTL + K D + F+ TT E++++ + LL
Sbjct 1453 KFDLTLTMREKEDTLVAAFEYSTDLFDRTTIERMAEHLQHLL 1494
Score = 53.5 bits (127), Expect = 4e-09
Identities = 86/415 (21%), Positives = 161/415 (39%), Gaps = 59/415 (14%)
Query 50 VQLSFTEERAWMLHQQDPLASSGPFILAFRLSGEIEISRLSNAIQKLYEGDSNLNLRY-D 108
V LSF ++R W L + P + A RL GE+++ +++ L + +L + D
Sbjct 3652 VPLSFAQQRLWFLDRLIPNSFLYNIPSAARLHGELDVEAWERSLKLLIQRHESLRTTFSD 3711
Query 109 LDDEGILNKYHDEHTPFEMNIHVV--------KSEQEAVQYLLSWIQKPINLAKAPAIQF 160
D E + H E ++ V + E +A+Q + ++P +L + P ++
Sbjct 3712 RDGEAV----QIIHPAIEWSLGRVDLREWAEAEREAKALQLAIEDAKRPFDLERGPLLRA 3767
Query 161 TLLPQSHHEVILGILGHHILLDDSAWQPIFAQLSQNYAQLDGVLTASNSHIELS------ 214
+LL + E + + HHI+ D + +L Y L T + + L
Sbjct 3768 SLLVMAQQEYVFLLNLHHIVADGWSMNVFMEELVTIYEALSAGETPQLAELPLQYADYAA 3827
Query 215 ---SKIPAKVLVNSQNALQYWKTIFPTGLNQLDWPKFCRAPNVQASIIQYGQNTIFDYEQ 271
+ VL + L YWK L P P VQ+
Sbjct 3828 WQRDWLQGDVL---EQQLAYWKAKVGGAEPLLALPTDRPRPAVQS--------------H 3870
Query 272 KAVRCSSSIP---LKGLKQLSERAQASIFHTVVAQFGGYLNHLFGTQSIDLFVPIVEQYE 328
K + ++P L LK LS +++F T++A F L G I + P+ +
Sbjct 3871 KGAMHTITLPAERLAALKTLSREEGSTLFMTLLAAFQTLLYRYSGQSDIVVGSPVAGRNR 3930
Query 329 ASSLSQIRSSSNILPIRILRPEYSEQESNIENKEKESIVNVRNQILQGMVH-NISIEQIL 387
+ S I N L +R + + E ++ + VR L+ H ++ E+++
Sbjct 3931 QETESLIGFFINTLAMR--------TDLSGEPTFRDLLGKVRETALEAYAHQDLPFEKLV 3982
Query 388 SATKTKRNTIPNVLVTQFIDGSQFLKLEQVETSTLIIPPIH-------SDYDLTL 435
+ +R+ + L Q + Q + ++ S + + P H + +D+TL
Sbjct 3983 DELELERSLSYSPLF-QVMFVLQNIPMDAQALSHIRLEPFHIGQEGVSAKFDITL 4036
Score = 51.6 bits (122), Expect = 1e-08
Identities = 89/440 (20%), Positives = 173/440 (39%), Gaps = 54/440 (12%)
Query 24 GLSERIS--TEAVEHYTENQIINIEKNG-VQLSFTEERAWMLHQQDPLASSGPFILAFRL 80
G+SE+++ E T ++ + ++ + LSF ++R W L + P ++ A R+
Sbjct 6207 GMSEKLAGLLEEQSGVTSIPLVPVPRDKQLPLSFAQQRLWFLDRLMPDSALYNIPSAVRI 6266
Query 81 SGEIEISRLSNAIQKLYEGDSNLNLRY-DLDDEGILNKYHD--EHTPFEMNIHVVKSEQE 137
G++ I ++Q + E +L + D+ E + H+ E E+++ + E+
Sbjct 6267 QGQLNIRAWERSLQTIIERHESLRTTFTDIGGEAV-QVIHEMMEWRLVEIDLRDLPDEER 6325
Query 138 --AVQYL-LSWIQKPINLAKAPAIQFTLLPQSHHEVILGILGHHILLDDSAWQPIFAQLS 194
AVQ L + +P NL P ++ TL+ + + + HHI+ D + +L+
Sbjct 6326 EAAVQRLEKAEASQPFNLRTGPLLRATLIQTGEEDFVFLLNMHHIVSDGWSMSIFMGELA 6385
Query 195 QNYAQLDGVLTASNSHIELS---------SKIPAKVLVNSQNALQYWKTIFPTGLNQLDW 245
Y L T + + L + +VL + L YW+ L
Sbjct 6386 TIYEALSKGDTPQLAEMPLQYADFAAWQRDWLQGEVL---EQQLAYWREKLGAAEPMLAL 6442
Query 246 PKFCRAPNVQASIIQYGQNTIFDYEQKAVRCSSSIPL---KGLKQLSERAQASIFHTVVA 302
P P VQ +++ PL + L LS + A++F T++A
Sbjct 6443 PTDRPRPAVQT--------------HHGALYTTAFPLALTEKLHALSRQEGATLFMTLLA 6488
Query 303 QFGGYLNHLFGTQSIDLFVPIVEQYEASSLSQIRSSSNILPIRILRPEYSEQESNIENKE 362
F L G I + P+ + + + S I N L +R + +
Sbjct 6489 AFQTLLYRYSGQDDIIVGSPVAGRNKQETESMIGFFINTLAMR--------TDMSGAPTF 6540
Query 363 KESIVNVRNQILQGMVH-NISIEQILSATKTKRNTIPNVLVTQFIDGSQFLKLEQVETST 421
+E + VR+ L+ H ++ E+++ + +R+ + L F L +
Sbjct 6541 RELLARVRDTALEAYTHQDLPFEKLIDELELERSLSYSPLFQVMFALQNFQMLTREFEGI 6600
Query 422 LIIP------PIHSDYDLTL 435
I+P + S YD++L
Sbjct 6601 EIVPFESKNEAVMSKYDISL 6620
Score = 46.6 bits (109), Expect = 5e-07
Identities = 62/288 (22%), Positives = 118/288 (41%), Gaps = 20/288 (7%)
Query 523 FKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTALELSQCVE 582
+K VL ++ DNFF+ GG SIL+ +++ + Q G+ + T EL+ V
Sbjct 4634 WKNVLGLADVGIHDNFFELGGDSILSIQIVSR-ANQAGIRLTPKQLLANQTIAELAS-VA 4691
Query 583 YLSDRVKDSSVADDNREIV--APLTLLQKAFMGFSNQGRDAMYNIPFAFRFSETVNEQAF 640
++D + + + ++ + PLT +Q F S Q +N + V+
Sbjct 4692 TVTDESEATKLPNEQGIVTGDVPLTPIQTWFFA-SEQPSVHHWNQSLLLTVQQPVDLAVL 4750
Query 641 YDAFLDILKRHHVMRSIFVQADQG-----EIFQTVIPMDRLNQHPWFWGSEHQVGQSAQQ 695
+L H +R + + +QG E IP ++ + +E ++ +
Sbjct 4751 ERTIECLLAHHDALRMRYSRTEQGWTQRIEGLPETIPFRSVDLSAFPTTAEQEM---RLE 4807
Query 696 ILRAEANHSFDLMQEFPI--RVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYT 753
+ +E S DL E P+ V F + L ++ +H+ +D S IL+ +L AY
Sbjct 4808 EIASEVQASLDL-TEGPVVQAVYFQLGAEQPGRLLIVAHHLVVDGVSWRILLEDLQTAYE 4866
Query 754 SRVDGKAPIWEKTPRQFHEYA----MAQDDSALQAHIQYWMNTIGKIK 797
G+A F +A + AL+ +W+ + ++K
Sbjct 4867 QLAKGQAVQLAAKTTSFKTWAEQLRLYATSEALRQEKAFWLEQMDEVK 4914
Score = 43.1 bits (100), Expect = 6e-06
Identities = 62/295 (21%), Positives = 118/295 (40%), Gaps = 33/295 (11%)
Query 515 ITQLILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTA 574
+ +++ +K+VL + DNFF+ GG SIL+ +++ + Q G+ + +P
Sbjct 7205 VEKVLAQIWKEVLGVEEVGIHDNFFELGGDSILSIQIVAR-AGQSGIRL-------SPKL 7256
Query 575 LELSQCVEYLSDRVKDS-SVADDNREIVAPLTLLQKAFMGFSNQGRDAMYNIPFAFRFSE 633
L +Q + LS V DS + + + + LL F + D + +
Sbjct 7257 LFENQTIAELSHAVGDSVHICAEQGLVTGEVPLLPIQHWFFEQKLADRNHWNQSVLLTVQ 7316
Query 634 TVNEQAFYDAFLDILKRHHVMRSIFVQAD-----QGEIFQTVIPMDRLNQHPWFWGSEHQ 688
++ + AF +L H +R F + G + +IP + +
Sbjct 7317 PIDPEILKQAFYHLLGHHDALRLRFYHQNGAWKQAGAEWTDIIPFYVVEL------GDLP 7370
Query 689 VGQSAQQI--LRAEANHSFDLMQEFPIRVRFMKDEQGQH-ILSMLLYHIAMDEWSSGILM 745
Q +QI L EA S L +R + GQ L ++++H+A+D S I+
Sbjct 7371 ANQQVEQIEKLSGEAQASLHLADGPLLRAVYFDMGAGQEGRLLIVIHHLAVDGVSWRIIT 7430
Query 746 RELIQAYTSRVDG-------KAPIWEKTPRQFHEYAMAQDDSALQAHIQYWMNTI 793
+L +A + G K ++ + EYA + +L YW++ +
Sbjct 7431 EDLNKACNQLLQGKQVQLPPKTSSYKYWAEKLVEYAAS---DSLTEEADYWLSRL 7482
Score = 41.2 bits (95), Expect = 2e-05
Identities = 36/171 (21%), Positives = 74/171 (43%), Gaps = 16/171 (9%)
Query 55 TEERAWMLHQQDPLASSGPFILAFRLSGEIEISRLSNAIQKLYEGDSNLNLRYDLDDEGI 114
T + W + P L + ++++ L I+ L L +RY ++G
Sbjct 4716 TPIQTWFFASEQPSVHHWNQSLLLTVQQPVDLAVLERTIECLLAHHDALRMRYSRTEQGW 4775
Query 115 LNKYHD--EHTPF---EMNIHVVKSEQEA-VQYLLSWIQKPINLAKAPAIQ---FTLLPQ 165
+ E PF +++ +EQE ++ + S +Q ++L + P +Q F L +
Sbjct 4776 TQRIEGLPETIPFRSVDLSAFPTTAEQEMRLEEIASEVQASLDLTEGPVVQAVYFQLGAE 4835
Query 166 SHHEVILGILGHHILLDDSAWQPIFAQLSQNYAQLDGVLTASNSHIELSSK 216
++ I+ HH+++D +W+ + L Y QL A ++L++K
Sbjct 4836 QPGRLL--IVAHHLVVDGVSWRILLEDLQTAYEQL-----AKGQAVQLAAK 4879
Score = 40.4 bits (93), Expect = 4e-05
Identities = 35/156 (22%), Positives = 65/156 (42%), Gaps = 12/156 (8%)
Query 55 TEERAWMLHQQDPLASSGPFILAFRLSGEIEISRLSNAIQKLYEGDSNLNLRYDLDDEGI 114
T + W P L + +++S L AI L L + + D
Sbjct 2137 TPIQKWFFAADQPSLHHWNQSLLLTVQQPVDVSVLERAIASLLSHHDALRMSFSFVDGAW 2196
Query 115 LNKYHD--EHTPFEM----NIHVVKSEQEA-VQYLLSWIQKPINLAKAPAIQ---FTLLP 164
+ + +HTPF ++ + EQ A ++ + S +Q +N+A+ +Q F L
Sbjct 2197 TQQMNGLGDHTPFRCVDLSDLSTQEQEQAARLEEIASEVQASLNIAEGNVVQAVYFNLGE 2256
Query 165 QSHHEVILGILGHHILLDDSAWQPIFAQLSQNYAQL 200
Q ++L + HH+++D +W+ + L Y QL
Sbjct 2257 QKAGRLLLVV--HHLVVDGVSWRILLEDLQHAYEQL 2290
Score = 24.3 bits (51), Expect = 3.0
Identities = 17/65 (26%), Positives = 31/65 (48%), Gaps = 1/65 (2%)
Query 137 EAVQYLLSWIQKPINLAKAPAIQFTLLPQ-SHHEVILGILGHHILLDDSAWQPIFAQLSQ 195
E ++ L Q ++LA P ++ + E L I+ HH+ +D +W+ I L++
Sbjct 7376 EQIEKLSGEAQASLHLADGPLLRAVYFDMGAGQEGRLLIVIHHLAVDGVSWRIITEDLNK 7435
Query 196 NYAQL 200
QL
Sbjct 7436 ACNQL 7440
>Q70LM4 ATP-dependent D-leucine adenylase / Leucine racemase [ATP-hydrolyzing]
/ ATP-dependent tryptophan adenylase / ATP-dependent
glycine adenylase / Linear gramicidin--PCP reductase
[Brevibacillus parabrevis]
Length=5085
Score = 143 bits (361), Expect = 1e-36
Identities = 139/561 (25%), Positives = 251/561 (45%), Gaps = 45/561 (8%)
Query 500 WAQPTSS-VQPQVDASITQLILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQ 558
W Q T++ V P+ + ++I + F +VL + DDNFF+ GGHS+LAT+ + +L+
Sbjct 3535 WGQITAAYVAPR--NPLEEMIANVFAEVLAVEKVGIDDNFFELGGHSLLATQTVSRLREI 3592
Query 559 HGLLIKIADFFNAPTALELSQCVEYL---SDRVKDSSVADDNREIVAPLTLLQKAFMGFS 615
G+ +++ F PT L + +E L S R + +R+ PL+ Q+ + F
Sbjct 3593 VGVELQLRTLFEHPTVAGLGEQLELLTKQSSRKLAPPIGKVSRKEPLPLSFTQQR-LWFL 3651
Query 616 NQ--GRDAMYNIPFAFRFSETVNEQAFYDAFLDILKRHHVMRSIFVQADQGEIFQTVIP- 672
Q ++ NIP R ++ A+ +F I+ RH +R+ F D G Q + P
Sbjct 3652 EQFTQNSSINNIPSFLRIQGELDVAAWEASFSAIILRHESLRTSFEVRD-GRPVQVIQPH 3710
Query 673 ----MDRLNQHPWFWGS-EHQVGQSAQQILRAEANHSFDLMQEFPIRVRFMKDEQGQHIL 727
M R++ E ++ + A+Q + FDL + +R ++ + +
Sbjct 3711 GDWAMTRIDLRALEPAEREAEIKRLAEQAIV----QPFDLTKGLLLRASLVQLDANDFVF 3766
Query 728 SMLLYHIAMDEWSSGILMRELIQAYTSRVDGKAPIWEKTPRQFHEYAMAQDD----SALQ 783
+++HIA D WS GIL+ EL+ Y + G+A + P Q+ ++A+ Q + L
Sbjct 3767 LFVMHHIASDGWSMGILLSELMTNYKAFRQGEASPLGELPIQYADFAVWQREWLSGEVLA 3826
Query 784 AHIQYWMNTIGKIKKQQPLLPAYRNDVDMPPPENNLDDVSGAAVEFNFTAIQVEQLYALA 843
+ YW K+K +PLL D P P + G + F A ++QL +L+
Sbjct 3827 EQLGYWRE---KLKGSEPLLQL---PTDRPRPP--VQTYEGEKMSVQFGAELLKQLQSLS 3878
Query 844 RQYRSSLFYVVYAGLLLTTYYLGAGKKVLSGTSVACRQDPNYQDTLGYFTNVVMHYIQFN 903
R+ ++LF ++A Y +L GT +A R + +GYF N ++ +
Sbjct 3879 RKEGATLFMTLFAAFQTLLYRYTNQDDILVGTPIAGRNKQETEQLIGYFINTLVLRTDMS 3938
Query 904 ESLSIKDLVNQVQNNIFKAQEYADIPFAIVEDNIRAEGEEWTESPYEVYVQLH---AQNA 960
S ++L+ +V+ +A + D+PF + D ++ E ++V L Q
Sbjct 3939 GHPSFRELLARVRETALEAYAHQDVPFEKLLDELQLERSMSYSPLFQVMFILQNIPVQAE 3998
Query 961 LTGVFQLNSGDEIGFELIEPERDTAKFGLHFEVYEEPSSEKERLRVVINYRVNRYNEIQI 1020
G QL+S D +E T+KF + + E P + L + Y ++ I
Sbjct 3999 PAGDIQLSSFD------LELGAVTSKFDMTVTMVETP----DGLLATLEYNKALFDSSTI 4048
Query 1021 QLIRQVAQQVLESFIHIDTQS 1041
+ + +++E + QS
Sbjct 4049 TRMVEHFHKLMEEIVANPDQS 4069
Score = 141 bits (356), Expect = 5e-36
Identities = 107/437 (24%), Positives = 200/437 (46%), Gaps = 25/437 (6%)
Query 517 QLILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTALE 576
+++ + + QVL + + D+FF+ GGHS+LAT+ + +L+ G+ + + F T +
Sbjct 969 EMVANIWSQVLSVERVGSFDDFFELGGHSLLATQTVSRLKEAFGVDLPLRVLFECSTVNK 1028
Query 577 LSQCVEYLSDRVKDSS---VADDNREIVAPLTLLQKAFMGFSN-QGRDAMYNIPFAFRFS 632
LS+ + + S + +R+ PL+ Q+ F A+YNIP A R
Sbjct 1029 LSEWIAAAGEDKSGLSRIPLVPVSRDRHLPLSFAQQRLWFFDRLMPNSALYNIPTAVRLQ 1088
Query 633 ETVNEQAFYDAFLDILKRHHVMRSIFVQADQGEIFQTVIP-----MDRLNQHPWFWGSEH 687
++ A + I++RH +R+ F + GE + P ++R++ SE
Sbjct 1089 GELDMDALEQSLQTIIQRHESLRTTFTDHN-GEAVSVIHPEIDWKLERIDLRE---RSEE 1144
Query 688 QVGQSAQQILRAEANHSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRE 747
++ ++ + EAN FDL+ +R ++ ++ I + ++HI D WS+GIL+RE
Sbjct 1145 MRNEAGLRLAKEEANRPFDLVTGPLMRATIIQTDERDFIFLLNVHHIIADGWSAGILIRE 1204
Query 748 LIQAYTSRVDGKAPIWEKTPRQFHEYAMAQDD----SALQAHIQYWMNTIGKIKKQQPLL 803
L Y + +AP + P Q+ +YA Q + L + YW K+ +PLL
Sbjct 1205 LFHCYQAFAKAEAPQLAELPIQYADYAYWQREWLTSDVLDEQLSYWR---AKLGGAEPLL 1261
Query 804 PAYRNDVDMPPPENNLDDVSGAAVEFNFTAIQVEQLYALARQYRSSLFYVVYAGLLLTTY 863
D P P + +G+++ F L AL+++ ++LF + A + Y
Sbjct 1262 AL---PTDRPRPA--VQSYAGSSISLLFDDELRANLLALSKREGTTLFMTLLAAFQVFLY 1316
Query 864 YLGAGKKVLSGTSVACRQDPNYQDTLGYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQ 923
+L GT A R + +G+F N ++ + S K+++ +V+ A
Sbjct 1317 RYTGQDDILVGTPEAGRSRQETEGLIGFFINTLVMRTDLSGEPSFKEVLARVRETALGAY 1376
Query 924 EYADIPFAIVEDNIRAE 940
+ D+PF + D + E
Sbjct 1377 AHQDLPFEKLVDELNVE 1393
Score = 62.0 bits (149), Expect = 1e-11
Identities = 75/347 (22%), Positives = 136/347 (39%), Gaps = 18/347 (5%)
Query 596 DNREIVAPLTLLQKAFMGFSN-QGRDAMYNIPFAFRFSETVNEQAFYDAFLDILKRHHVM 654
+N E P+T LQ+ + S + Y + + +N F A+ ++ RH +
Sbjct 2 NNIETYYPVTPLQQGLIFHSLLEPESGAYIVQMGLKLQGPLNIPLFEQAWQCLVDRHAIF 61
Query 655 RSIFVQADQGEIFQTVIPMDRLN--QHPWFWGSEHQVGQSAQQILRAEANHSFDLMQEFP 712
R+ FV E Q V+ +++ +H S + + + FD+ Q
Sbjct 62 RTRFVGGKVKEYVQVVLKDLKISLVEHDLIHLSSSEQEAFLHHFAKEDRKRGFDIEQAPL 121
Query 713 IRVR-FMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTSRVDGKAPIWEKTPRQFH 771
+R+ F + + H L L+H+ +D WS ++ E+ AY G+ P+ R +
Sbjct 122 MRLNVFHLNSETVHFL-WTLHHVLIDGWSMPLVFGEVFAAYEMLSKGQ-PLSLPPVRAYR 179
Query 772 EYAMAQDDSALQAHIQYWMNTIGKIKKQQPLL--PAYRNDVDMPPPENNLDDVSGAAVEF 829
+Y + LQ +W + + PL AY+N LD ++
Sbjct 180 DYIVWLKKQDLQQAEAFWRTYMQGFTEATPLSFGRAYKNPY--------LDQKQYRELDL 231
Query 830 NFTAIQVEQLYALARQYRSSLFYVVY-AGLLLTTYYLGAGKKVLSGTSVACRQD-PNYQD 887
+ + L LARQ+R ++ +V A LL Y G V T D P +
Sbjct 232 TVSEQTSKALQTLARQHRLTVNTIVQGAWALLLNRYSGQDDIVFGATVSGRPADLPGVET 291
Query 888 TLGYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQEYADIPFAIVE 934
+G F N + +Q N S+ + + +Q ++Y P ++
Sbjct 292 MIGLFINTLPVRVQVNAEESVINWLKTLQQQQADFRQYEYTPLVEIQ 338
Score = 60.8 bits (146), Expect = 2e-11
Identities = 88/409 (22%), Positives = 169/409 (41%), Gaps = 48/409 (12%)
Query 523 FKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTALELSQCVE 582
+K VL + DNFF+ GG SIL+ +++ + Q GL + F T EL++ VE
Sbjct 2036 WKDVLGIEQIGIHDNFFELGGDSILSIQIVSR-ANQAGLSLAPKQLFEYQTIAELAEIVE 2094
Query 583 YLSDRVKDSSVADDNREIVAPLTLL--QKAFMGFSNQGRDAMYNIPFAFRFSETVNEQAF 640
+ ++V + + L LL QK F RD +N ++ A
Sbjct 2095 ------EKAAVQAEQGAVTGELPLLPIQKWFFRLPLANRD-HWNQSVLLSIQAGIDPAAL 2147
Query 641 YDAFLDILKRHHVMRSIFVQADQGEIFQTVIPMDRLNQHPWFWGSEHQVGQSAQ-QILRA 699
A ++ +H R + Q++ G + P + + P+ Q+ Q + A
Sbjct 2148 KQAVGQLMFQHDAFRMRYTQSESGWLQAMDAPSETI---PFRVEDLSQLAPEEQSSAIEA 2204
Query 700 EANHSFDLMQ----EFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTS- 754
AN + + + + F ++ L ++ +H+ +D S I++ +L AY
Sbjct 2205 IANETQTQLSLRAGQVVQTIYFHLGKEVPGRLLIVAHHLVVDGVSWRIILEDLQHAYQQI 2264
Query 755 ------RVDGKAPIWEKTPRQFHEYAMAQDDSALQAHIQYWMNTIGKIKKQQPLLPAYRN 808
++ K +++ ++ YA ++ A + YW++ K LPA
Sbjct 2265 AAGQEVKLPAKTTSYKEWAQELERYAHSE---AFKHEKSYWLS---KSSVHSTELPA--- 2315
Query 809 DVDMPPPENNLDDVSGAAVEFNFTAIQVEQLYALARQ----YRSSLFYVVYAGLLLTTYY 864
DMP N + A V+ ++ VE+ AL +Q YR+ + V+ A L
Sbjct 2316 --DMPDSAENTE----ATVKSVHFSLTVEETKALLQQVPQAYRTQINDVLLAALAKALGQ 2369
Query 865 LGAGKKVLSGTSVACRQD----PNYQDTLGYFTNVVMHYIQFNESLSIK 909
+ V R++ + T+G+FT++ ++Q++E+ S++
Sbjct 2370 WTGKRSVFVNVEGHGREELAEHLDLSRTVGWFTSMYPVHLQWDETFSVR 2418
Score = 50.4 bits (119), Expect = 3e-08
Identities = 76/365 (21%), Positives = 144/365 (39%), Gaps = 39/365 (11%)
Query 47 KNGVQLSFTEERAWMLHQQDPLASSGPFILAFRLSGEIEISRLSNAIQKLYEGDSNLNLR 106
K + LSFT++R W L Q +S R+ GE++++ + + +L
Sbjct 3636 KEPLPLSFTQQRLWFLEQFTQNSSINNIPSFLRIQGELDVAAWEASFSAIILRHESLRTS 3695
Query 107 YDLDDEGILNKYHDEHTPFEMN------IHVVKSEQEAVQYLLSWIQKPINLAKAPAIQF 160
+++ D G + H + M + + E E + I +P +L K ++
Sbjct 3696 FEVRD-GRPVQVIQPHGDWAMTRIDLRALEPAEREAEIKRLAEQAIVQPFDLTKGLLLRA 3754
Query 161 TLLPQSHHEVILGILGHHILLDDSAWQPIFAQLSQNY-------AQLDGVLTASNSHIEL 213
+L+ ++ + + HHI D + + ++L NY A G L + +
Sbjct 3755 SLVQLDANDFVFLFVMHHIASDGWSMGILLSELMTNYKAFRQGEASPLGELPIQYADFAV 3814
Query 214 SSK--IPAKVLVNSQNALQYWKTIFPTGLNQLDWPKFCRAPNVQASIIQYGQNTIFDYEQ 271
+ + +VL L YW+ L P P VQ ++ E+
Sbjct 3815 WQREWLSGEVLAEQ---LGYWREKLKGSEPLLQLPTDRPRPPVQT----------YEGEK 3861
Query 272 KAVRCSSSIPLKGLKQLSERAQASIFHTVVAQFGGYLNHLFGTQSIDLFVPIVEQYEASS 331
+V+ + + LK L+ LS + A++F T+ A F L I + PI + + +
Sbjct 3862 MSVQFGAEL-LKQLQSLSRKEGATLFMTLFAAFQTLLYRYTNQDDILVGTPIAGRNKQET 3920
Query 332 LSQIRSSSNILPIRILRPEYSEQESNIENKEKESIVNVRNQILQGMVH-NISIEQILSAT 390
I N L +LR + S S +E + VR L+ H ++ E++L
Sbjct 3921 EQLIGYFINTL---VLRTDMSGHPS-----FRELLARVRETALEAYAHQDVPFEKLLDEL 3972
Query 391 KTKRN 395
+ +R+
Sbjct 3973 QLERS 3977
Score = 48.1 bits (113), Expect = 2e-07
Identities = 89/441 (20%), Positives = 165/441 (37%), Gaps = 52/441 (12%)
Query 52 LSFTEERAWMLHQQDPLASSGPFILAFRLSGEIEISRLSNAIQKLYEGDSNLNLRYDLDD 111
LSF ++R W + P ++ A RL GE+++ L ++Q + + +L + +
Sbjct 1059 LSFAQQRLWFFDRLMPNSALYNIPTAVRLQGELDMDALEQSLQTIIQRHESLRTTFTDHN 1118
Query 112 EGILNKYHDEHTPFEMNIHVVKSEQE-----AVQYLLSWIQKPINLAKAPAIQFTLLPQS 166
++ H E I + + +E ++ +P +L P ++ T++
Sbjct 1119 GEAVSVIHPEIDWKLERIDLRERSEEMRNEAGLRLAKEEANRPFDLVTGPLMRATIIQTD 1178
Query 167 HHEVILGILGHHILLDDSAWQPIFAQLSQNYAQLDGVLTASNSHIELS---------SKI 217
+ I + HHI+ D + + +L Y + + + +
Sbjct 1179 ERDFIFLLNVHHIIADGWSAGILIRELFHCYQAFAKAEAPQLAELPIQYADYAYWQREWL 1238
Query 218 PAKVLVNSQNALQYWKTIFPTGLNQLDWPKFCRAPNVQASIIQYGQNTIFDYEQKAVRCS 277
+ VL L YW+ L P P VQ S + +FD E +A
Sbjct 1239 TSDVL---DEQLSYWRAKLGGAEPLLALPTDRPRPAVQ-SYAGSSISLLFDDELRA---- 1290
Query 278 SSIPLKGLKQLSERAQASIFHTVVAQFGGYLNHLFGTQSIDLFVPIVEQYEASSLSQIRS 337
L LS+R ++F T++A F +L G I + P + + I
Sbjct 1291 ------NLLALSKREGTTLFMTLLAAFQVFLYRYTGQDDILVGTPEAGRSRQETEGLIGF 1344
Query 338 SSNILPIRILRPEYSEQESNIENKEKESIVNVRNQILQGMVH-NISIEQILSATKTKRN- 395
N L ++R + S + S KE + VR L H ++ E+++ +R+
Sbjct 1345 FINTL---VMRTDLSGEPS-----FKEVLARVRETALGAYAHQDLPFEKLVDELNVERSL 1396
Query 396 ----------TIPNVLV-TQFIDGSQFLKLE---QVETSTLIIPPIHSDYDLTLAFQIKA 441
+ N+ V +DG + L LE QVET+ + ++ LA +
Sbjct 1397 SYSPLFQVMFVLQNIPVQADALDGIRILPLEGSQQVETTKFDLTLTMAEAANGLAATFEY 1456
Query 442 DEIHFELTTGEKLSKKIGLLL 462
+ FE T E++ LL
Sbjct 1457 NTALFERNTVERMIGHFSSLL 1477
Score = 44.3 bits (103), Expect = 2e-06
Identities = 44/170 (26%), Positives = 76/170 (45%), Gaps = 8/170 (5%)
Query 595 DDNREIVAPLTLLQKAFMGFSNQGRDAM-YNIPFAFRFSETVNEQAFYDAFLDILKRHHV 653
D E V L+ LQ+ + S +D+ Y + FA F + ++ A+ ++L RH +
Sbjct 2575 DRQIEDVYTLSPLQQGMLFHSLYNQDSGDYVVQFAVTF-QNLDVSVLEKAWQNVLDRHSI 2633
Query 654 MRSIFVQADQGEIFQTVIPMDR--LNQHPWFWGSEHQVGQSAQQILRAEANHSFDLMQEF 711
+R+ FV E Q V + L + W + L + SFD+ Q
Sbjct 2634 LRTHFVWEGLSEPHQVVRKDVKVTLTKEDWRHLQADVQDEMLAAFLEEDRRRSFDIAQAP 2693
Query 712 PIR--VRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTSRVDGK 759
R V KDE+ + + S +H+ +D WS I++ EL+ Y + +G+
Sbjct 2694 LSRWVVFQTKDEEYRFVWSF--HHVLLDGWSVPIVLNELLAHYAAISEGR 2741
Score = 43.9 bits (102), Expect = 3e-06
Identities = 24/76 (32%), Positives = 41/76 (54%), Gaps = 2/76 (3%)
Query 507 VQPQVDASITQLILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIA 566
V PQ I ++ + VL + DNFF+ GGHS+LAT++I K++ + L + +
Sbjct 4600 VAPQTPVEI--MLHAHWAAVLEMETIGVHDNFFEIGGHSLLATQLIFKVREELQLEVPLR 4657
Query 567 DFFNAPTALELSQCVE 582
F PT +++ +E
Sbjct 4658 ILFETPTIAGMAKTIE 4673
Score = 31.6 bits (70), Expect = 0.018
Identities = 43/196 (22%), Positives = 81/196 (41%), Gaps = 19/196 (10%)
Query 32 EAVEHYTENQIINIEKNGV--QLSFTEERAWMLHQQDPLASSGPFILAFRLSGE--IEIS 87
E E E + E+ V +L + W PLA+ + + LS + I+ +
Sbjct 2088 ELAEIVEEKAAVQAEQGAVTGELPLLPIQKWFFRL--PLANRDHWNQSVLLSIQAGIDPA 2145
Query 88 RLSNAIQKLYEGDSNLNLRYDLDDEGILNKYH--DEHTPF---EMNIHVVKSEQEAVQYL 142
L A+ +L +RY + G L E PF +++ + + A++ +
Sbjct 2146 ALKQAVGQLMFQHDAFRMRYTQSESGWLQAMDAPSETIPFRVEDLSQLAPEEQSSAIEAI 2205
Query 143 LSWIQKPINLAKAPAIQFTLLPQSHHEVI--LGILGHHILLDDSAWQPIFAQLSQNYAQL 200
+ Q ++L +Q T+ EV L I+ HH+++D +W+ I L Y Q+
Sbjct 2206 ANETQTQLSLRAGQVVQ-TIYFHLGKEVPGRLLIVAHHLVVDGVSWRIILEDLQHAYQQI 2264
Query 201 DGVLTASNSHIELSSK 216
A+ ++L +K
Sbjct 2265 -----AAGQEVKLPAK 2275
Score = 25.4 bits (54), Expect = 1.3
Identities = 17/74 (23%), Positives = 34/74 (46%), Gaps = 2/74 (3%)
Query 129 IHVVKSEQEAV--QYLLSWIQKPINLAKAPAIQFTLLPQSHHEVILGILGHHILLDDSAW 186
IH+ SEQEA + ++ ++ +AP ++ + + V HH+L+D +
Sbjct 91 IHLSSSEQEAFLHHFAKEDRKRGFDIEQAPLMRLNVFHLNSETVHFLWTLHHVLIDGWSM 150
Query 187 QPIFAQLSQNYAQL 200
+F ++ Y L
Sbjct 151 PLVFGEVFAAYEML 164
Score = 23.9 bits (50), Expect = 3.9
Identities = 29/148 (20%), Positives = 65/148 (44%), Gaps = 15/148 (10%)
Query 62 LHQQDPLASSGPFILAFRLSGE-IEISRLSNAIQKLYEGDSNLNLRYDLDDEGILNKYHD 120
L+ QD SG +++ F ++ + +++S L A Q + + S L + EG+ +
Sbjct 2596 LYNQD----SGDYVVQFAVTFQNLDVSVLEKAWQNVLDRHSILRTHFVW--EGLSEPHQV 2649
Query 121 EHTPFEMNI------HVVKSEQEAV--QYLLSWIQKPINLAKAPAIQFTLLPQSHHEVIL 172
++ + H+ Q+ + +L ++ ++A+AP ++ + E
Sbjct 2650 VRKDVKVTLTKEDWRHLQADVQDEMLAAFLEEDRRRSFDIAQAPLSRWVVFQTKDEEYRF 2709
Query 173 GILGHHILLDDSAWQPIFAQLSQNYAQL 200
HH+LLD + + +L +YA +
Sbjct 2710 VWSFHHVLLDGWSVPIVLNELLAHYAAI 2737
>A0A348AXX4 Nonribosomal peptide synthetase [Curvularia clavata]
Length=13041
Score = 134 bits (337), Expect = 9e-34
Identities = 127/542 (23%), Positives = 242/542 (45%), Gaps = 36/542 (7%)
Query 503 PTSSVQPQVDASITQLILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLL 562
P+ V P D + +++ +EF VL + DNFFDFGGHS++AT++ ++ +
Sbjct 9938 PSVRVPPTND--MERILCEEFADVL-GVEVGITDNFFDFGGHSLMATKLAARISRRVNAR 9994
Query 563 IKIADFFNAPTALELSQCVEYLSDRVKDSSVADDNREIVAPLTLLQKAFMGFSNQGRDAM 622
+ + F+ P ++L+ ++ S K + + F+ N G +
Sbjct 9995 VSVKSVFDHPVLVDLASTIKQDSIMHKPIPQTAYTGPVEQSFAQGRLWFLDQLNFGA-SW 10053
Query 623 YNIPFAFRFSETVNEQAFYDAFLDILKRHHVMRSIFVQADQGEIFQTVIPMDRLNQHPWF 682
Y +P A R +++ ++ A + +RH +R+ F + D G Q V P ++ +
Sbjct 10054 YLMPLALRLQGSLHVKSLTTALFALEQRHETLRTTFEEQD-GVGIQIVHPANKKDLRILD 10112
Query 683 WGSEHQVGQSAQQILRAEANHSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSG 742
E + ++L E DL E RV ++ + HILS++++HI D WS
Sbjct 10113 VSKEQNSDYA--KVLHKERTIPIDLTSEPGWRVSLIRLGEDDHILSIVMHHIISDGWSVD 10170
Query 743 ILMRELIQAYTSRVDGKAPI--WEKTPRQFHEYAMAQ----DDSALQAHIQYWMNTIGKI 796
+L +EL Q YT+ + G+ P+ + P Q+ ++++ Q + Q ++YW +
Sbjct 10171 VLRQELKQFYTAALKGQDPLAQIDALPIQYRDFSLWQKLPDQVAEHQRQLEYWAEQLADN 10230
Query 797 KKQQPLLPAYRNDVDMPPPENNLDDVSG--AAVEFNFTAIQVEQLYALARQYRSSLFYVV 854
+ L D+P P D +SG AV+ +QL A R +++++F V+
Sbjct 10231 TPAELL-------TDLPRP----DVLSGKAGAVQLTIDGPVFDQLQAFCRAHQTTMFTVL 10279
Query 855 YAGLLLTTYYLGAGKKVLSGTSVACRQDPNYQDTLGYFTNVVMHYIQFNESLSIKDLVNQ 914
A T Y L GT +A R P + +G+F N I + + + LV Q
Sbjct 10280 LAVFRTTHYRLTGATDATIGTPIANRNRPELERLVGFFVNTQCIRITVDVEDTFEALVRQ 10339
Query 915 VQNNIFKAQEYADIPFAIVEDNIRAEGEEWTESPY-EVYVQLHAQNALTGVFQLNSGDEI 973
V + A D+PF + I + + +P ++ +H+Q ++ FQL D
Sbjct 10340 VHSTSTTAFANQDVPFERIVSTILPGSRDASRNPLAQLMFAVHSQRDIS-KFQLEGLDTK 10398
Query 974 GFELIEPERDTAKFGLHFEVYEEPSSEKERLRVVINYRVNRYNEIQ--IQLIRQVAQQVL 1031
P + +F + F ++++ +E+ RV+ + IQ + + +++ ++ L
Sbjct 10399 PI----PTAASTRFDIEFHMFQQ--AERLSGRVLFAEDLFELETIQGMVVIFKEILRRGL 10452
Query 1032 ES 1033
E+
Sbjct 10453 ET 10454
Score = 133 bits (335), Expect = 2e-33
Identities = 111/465 (24%), Positives = 192/465 (41%), Gaps = 45/465 (10%)
Query 515 ITQLILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTA 574
+ ++ +EF VL + DNFFD GGHS++AT++ ++ + + D F+ P
Sbjct 11433 VEAVLCEEFTDVL-GVEVGITDNFFDLGGHSLMATKLAARISKHLDARVSVKDVFDYPVV 11491
Query 575 LELSQCVEYLSDRVKDSSVADDNREIVAPLTLLQKA--FMGFSNQGRDAMYNIPFAFRFS 632
+L+ +E S + + + N + Q F+ N G +Y +P A R
Sbjct 11492 ADLAASIERNS--IPHNPIPSTNYSGPVEQSFAQGRLWFLDQLNMGVSELYLMPLALRLR 11549
Query 633 ETVNEQAFYDAFLDILKRHHVMRSIFVQADQGEIFQTVIPMDRLNQHPWFWGSEHQVGQS 692
+ AF A + RH +R+ F+ D G Q ++P + +
Sbjct 11550 GPLRVDAFAAAVSALEARHETLRTTFMDHD-GVGMQVILPSNSKKLRVIDASENDYI--- 11605
Query 693 AQQILRAEANHSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAY 752
ILR E F+L E R+ ++ Q ILS++++HI D WS +L REL + Y
Sbjct 11606 --DILRQERTAPFNLTTEPGFRIALLQLGQTDFILSIVMHHIIYDGWSIDVLCRELGRFY 11663
Query 753 TSRVDGKAP---------------IWEKTPRQFHEYAMAQDDSALQAHIQYWMNTIGKIK 797
++ + G+ P IW+K P Q E+ + +QYW +
Sbjct 11664 SAALQGQDPLAQVSPLPIQYRDFSIWQKRPEQVAEH---------ERQLQYWTEQLADSS 11714
Query 798 KQQPLLPAYRNDVDMPPPENNLDDVSGAAVEFNFTAIQVEQLYALARQYRSSLFYVVYAG 857
+ L D+P P + V+ E+L A R ++++ F V+ A
Sbjct 11715 PAELL-------TDLPRP--LVPTGKAGIVQLTIEGAVYERLRAFCRVHQTTSFAVLLAA 11765
Query 858 LLLTTYYLGAGKKVLSGTSVACRQDPNYQDTLGYFTNVVMHYIQFNESLSIKDLVNQVQN 917
T Y L + G+ +A R P + +G+F N + E + LV QV+
Sbjct 11766 FRATHYRLTGAEDATIGSPIANRNRPELESLIGFFVNTQCIRVTIREDDTFDKLVQQVRA 11825
Query 918 NIFKAQEYADIPFAIVEDNIRAEGEEWTESP-YEVYVQLHAQNAL 961
AQ D+PF + + + + +P ++ LH+Q+ L
Sbjct 11826 TTTAAQVNQDVPFERIVSALMPGSRDTSRNPLVQLSFALHSQHDL 11870
Score = 132 bits (331), Expect = 5e-33
Identities = 116/491 (24%), Positives = 211/491 (43%), Gaps = 31/491 (6%)
Query 515 ITQLILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTA 574
I ++ +EF +L + DNFFD GGHS++AT + +L + I + D F+ P
Sbjct 1870 IEAVLCEEFAHIL-GVEIGVTDNFFDLGGHSLMATTLAARLARRLNASISVKDVFDQPIV 1928
Query 575 LELSQCVEYLSDRVKDSSVADDNREIVAPLTLLQKAFMGFSNQGRDAMYNIPFAFRFSET 634
L+ ++ S + + + F+ N G A Y++P A R
Sbjct 1929 ANLAATIKRGSTPHNAIPPTKYSGPVEQSFAQGRLWFLDQLNLGA-AWYHMPLAVRLRGP 1987
Query 635 VNEQAFYDAFLDILKRHHVMRSIFVQADQGEIFQTVIPMDRLNQHPWFWGSEHQVGQSAQ 694
++ +A A + +RH +R++F + D G Q V P + P +
Sbjct 1988 LHLEALTAALHALEERHETLRTVFEEQD-GVGMQIVRPSSKT---PLRIIDVSTKERGYA 2043
Query 695 QILRAEANHSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTS 754
++L+ E FDL E RV ++ + HILS++++HI D WS IL EL Q Y +
Sbjct 2044 ELLKQEQTTPFDLATELGWRVALLRQGKDDHILSIVIHHIISDGWSLDILCEELGQFYAA 2103
Query 755 RVDGKAPIWEKTPR--QFHEYAM--AQDDSALQAH--IQYWMNTIGKIKKQQPLLPAYRN 808
+ G+ P+ + +P Q+ ++++ Q + + H ++YW + + L
Sbjct 2104 VLRGQDPLAQISPLPIQYRDFSLWQKQPEQVAEHHRQLEYWTTQLEGSVPAELL------ 2157
Query 809 DVDMPPPENNLDDVSGAAVEFNFTAIQVEQLYALARQYRSSLFYVVYAGLLLTTYYLGAG 868
D+P P + + E+L A +R ++++ F V+ A T Y L
Sbjct 2158 -TDLPRP--TIQSGKAGVIPITVNGPVYERLRAFSRAHQTTAFAVLLAAFRATHYRLSGV 2214
Query 869 KKVLSGTSVACRQDPNYQDTLGYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQEYADI 928
GT +A R P ++ +G+F N I + + + LV Q++ A D+
Sbjct 2215 ADATIGTPIANRNRPELENMIGFFVNAQCMRITVEQDDTFETLVRQIRFTATAAFANQDV 2274
Query 929 PFAIVEDNIRAEGEEWTESP-YEVYVQLHAQNALTGVFQLNSGDEIGFELIEPERDT--A 985
PF + + + + + +P ++ LHA L + E+ + EP T
Sbjct 2275 PFEHIVSALMPDSRDTSRNPLVQLMFALHAYKDLGKI-------ELEGYVAEPVHTTLST 2327
Query 986 KFGLHFEVYEE 996
+F L F +++E
Sbjct 2328 RFDLEFHMFQE 2338
Score = 131 bits (329), Expect = 8e-33
Identities = 115/492 (23%), Positives = 211/492 (43%), Gaps = 41/492 (8%)
Query 518 LILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTALEL 577
++ +EF VL + DNFFD GGHS++AT++ ++ + + + D F+ P ++L
Sbjct 3361 VLCEEFTDVL-GLEVGITDNFFDLGGHSLMATKLAARISRRLDARVSVKDVFDQPVIVDL 3419
Query 578 SQCVEYLSDRVKDSSVADDNREIVAPLTLLQKAFMGFSNQGRDAMYNIPFAFRFSETVNE 637
+ + S + + + + + F+ N G ++Y +P A R +
Sbjct 3420 AASIRRGSTPHNPITPTEYSGPVEQSFAQGRLWFLDQLNLGA-SLYLMPLALRLRGPLRI 3478
Query 638 QAFYDAFLDILKRHHVMRSIFVQADQGEIFQTVIPMDRLNQHPWFWGSEHQVGQSA---Q 694
A A + +RH +R++F + D G Q + P + + SA
Sbjct 3479 DALTAALFALEQRHETLRTVFKEQD-GVGIQIIQPSQKKKLRT--------IDVSAGDFS 3529
Query 695 QILRAEANHSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTS 754
+ L E FDL E RV ++ E H+LS++++HI D WS IL +EL Q Y +
Sbjct 3530 EALHHERTAPFDLASEPGFRVALLQLEPSDHVLSIVMHHIIYDGWSIDILCQELGQFYAA 3589
Query 755 RVDGKAPIWEKTPR--QFHEYAMAQDD----SALQAHIQYWMNTIGKIKKQQPLLPAYRN 808
+ G+ P+ + +P Q+ ++++ Q + + + YW++ + + L
Sbjct 3590 AIQGQDPLGQVSPLPIQYRDFSVWQKQPEQVAEHERQLAYWIDQLADSAPAEFL------ 3643
Query 809 DVDMPPPENNLDDVSGAAVEFNFTAIQVEQLYALARQYRSSLFYVVYAGLLLTTYYLGAG 868
VD+P P D V ++L A R ++++ F V+ A T Y L
Sbjct 3644 -VDLPRPPVLSGD--AGLVHLTIDGPIYDRLRAFCRVHQTTTFAVLLAAFRATHYRLTGA 3700
Query 869 KKVLSGTSVACRQDPNYQDTLGYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQEYADI 928
+ GT +A R P ++ +G+F N I + + + LV QV++ A D+
Sbjct 3701 EDATVGTPIANRNRPELENLVGFFVNTQCMRISVGDDDTFEQLVRQVRSTATAAFANQDV 3760
Query 929 PFAIVEDNIRAEGEEWTESPYEVYVQLHAQNALTGVFQLNSGDEIGFELIE----PERDT 984
PF + + + +P VQL + V L +I FE + P
Sbjct 3761 PFERIVSTLLPGSRDTARNP---LVQL-----MFAVHSLKDLGKIQFEGLVGETIPTASF 3812
Query 985 AKFGLHFEVYEE 996
+F + F +++E
Sbjct 3813 TRFDVEFHLFQE 3824
Score = 129 bits (325), Expect = 2e-32
Identities = 125/530 (24%), Positives = 232/530 (44%), Gaps = 38/530 (7%)
Query 510 QVDASITQLILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFF 569
+++A++ ++ +D L+ + DNFF+ GGHS++AT++ ++ + I + D F
Sbjct 7390 EIEAALCEVFVD-----LLGTEVSITDNFFNLGGHSLMATKLAARISRRLDARISVKDVF 7444
Query 570 NAPTALELSQCVEYLSDRVKDSSVADDNREIVAPLTLLQKAFMGFSNQGRDAMYNIPFAF 629
+ P +L+ V+ S + + + F+ N G Y P A
Sbjct 7445 DYPVLADLAGAVQRGSTPHNPIVATPYSGPVEQSFAQGRLWFLDQLNAG-SLWYIQPIAV 7503
Query 630 RFSETVNEQAFYDAFLDILKRHHVMRSIFVQADQGEIFQTVIPMDRLNQHPWFWGSEHQV 689
R ++N A A + KRH +R+ F + D G Q V P + +Q
Sbjct 7504 RVRGSLNIGALTTALNALEKRHEPLRTTFEEHD-GIGVQVVQPHQPKKLRIVDTVANYQ- 7561
Query 690 GQSAQQILRAEANHSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELI 749
+ LR E F+L E RV ++ + +ILS++++HI D WS IL ++L
Sbjct 7562 -GDFIRALRKEQQTLFNLATEPGWRVSLLRIGEDDNILSIVMHHIISDGWSVDILRQDLK 7620
Query 750 QAYTSRVDGKAPIWEKTPRQFHEYAMAQDD----SALQAHIQYWMNTIGKIKKQQPLLPA 805
Y + + + P + P Q+ ++A Q + Q + YW+ + K + +
Sbjct 7621 LFYAAALKSQEPQVDALPIQYRDFAFWQKQPEQVAEHQRQLDYWIEQLKDSKPAELI--- 7677
Query 806 YRNDVDMPPPENNLDDVSGAA--VEFNFTAIQVEQLYALARQYRSSLFYVVYAGLLLTTY 863
D P PE +SG A V+ E L A R ++++ F V+ A Y
Sbjct 7678 ----TDFPRPEV----LSGTAGIVQLAVDGQVYEGLRAFCRIHQTTSFVVLLAAFRAAHY 7729
Query 864 YLGAGKKVLSGTSVACRQDPNYQDTLGYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQ 923
L + G+ +A R P + +G+F N I E + + LV QV++ A
Sbjct 7730 RLTGTEDATIGSPIANRNRPELESLIGFFVNTQCMRIMVGEDDTFERLVQQVRSTTTAAF 7789
Query 924 EYADIPFAIVEDNIRAEGEEWTESP-YEVYVQLHAQNALTGVFQLNSGDEIGFELIEPER 982
D+PF + ++++ + + +P ++ LH+Q + G+ +L G E R
Sbjct 7790 ANQDVPFERIVSSVQSTSRDASRNPLVQLMFALHSQQGI-GLMELE-----GVETEPIAR 7843
Query 983 D-TAKFGLHFEVYEEPSSEKERLRVVINYRVNRYNEIQIQLIRQVAQQVL 1031
D + +F + F +Y+ ++E L V+++ + + IQ + V Q++L
Sbjct 7844 DVSTRFDIEFHLYQ----KEESLHGVVHFAADLFEPETIQGLVSVFQEIL 7889
Score = 128 bits (322), Expect = 5e-32
Identities = 121/524 (23%), Positives = 226/524 (43%), Gaps = 30/524 (6%)
Query 515 ITQLILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTA 574
I ++ +E+ +VL + DNFFD GGHS++AT++ + + + + D F+ P
Sbjct 4417 IETILCEEYAEVL-GVEVGVMDNFFDLGGHSLMATKLAARATRRLDAKLSVKDIFDYPIL 4475
Query 575 LELSQCVEYLSDRVKDSSVADDNREIVAPLTLLQKAFMGFSNQGRDAMYNIPFAFRFSET 634
L+ V+ S + + + F+ N G + Y P A R +
Sbjct 4476 ANLAAAVQRGSTPHNAILATTYSGPVEQSFAQGRLWFLDQLNVGSN-WYLQPIAIRIRGS 4534
Query 635 VNEQAFYDAFLDILKRHHVMRSIFVQADQGEIFQTVIPMDRLNQHPWFWGSEHQVGQSAQ 694
+N A A + +RH +R+ F + D G Q V D + +++ +
Sbjct 4535 LNINALTTALHALEQRHETLRTTFEEED-GVGMQVVQEYDPIELRIMDIAADYDGDYT-- 4591
Query 695 QILRAEANHSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTS 754
+ L+ E FDL E RV ++ HILS++L+HI D WS +L +EL Q Y +
Sbjct 4592 EALKGEQTTPFDLESEPGWRVSLLRMNDNDHILSLVLHHIISDGWSVDVLRQELKQFYAA 4651
Query 755 RVDGKAPI--WEKTPRQFHEYAMAQDD----SALQAHIQYWMNTIGKIKKQQPLLPAYRN 808
+ G P+ + P Q+ ++++ Q + + ++YW+ + L
Sbjct 4652 ALQGLDPLSGADPLPIQYRDFSLWQKQPEQVAEHERQLKYWVEQLADNSPATLL------ 4705
Query 809 DVDMPPPENNLDDVSGAAVEFNFTAIQVEQLYALARQYRSSLFYVVYAGLLLTTYYLGAG 868
D P P ++ +V + E+L A R ++++ F V+ A + L
Sbjct 4706 -ADRPRP--SVLSGQAGSVPLSIEGQVYEKLQAFCRAHQTTSFSVLLAAFRAAHFRLTGV 4762
Query 869 KKVLSGTSVACRQDPNYQDTLGYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQEYADI 928
G +A R P + +G+F N I E + + L+ QV + A D+
Sbjct 4763 DDATIGIPIANRNRPELEHLIGFFVNRQCMRITVGEDDTFESLIRQVHSTATAAYANQDV 4822
Query 929 PFAIVEDNIRAEGEEWTESP-YEVYVQLHAQNALTGVFQLNSGDEIGFELIEPERDTAKF 987
PF + ++ + + + +P ++ +H+Q L G F+L ++ E + T +F
Sbjct 4823 PFERIVSSLLSGSRDTSRNPLVQLVFAVHSQKNL-GKFEL---QDLTSEPVAGAIST-RF 4877
Query 988 GLHFEVYEEPSSEKERLRVVINYRVNRYNEIQIQLIRQVAQQVL 1031
F +++ E+ERL V+ Y + ++ IQ + V Q++L
Sbjct 4878 DAEFHLFQ----EEERLNGVVYYATDLFDAETIQGVVSVFQEIL 4917
Score = 128 bits (321), Expect = 7e-32
Identities = 120/511 (23%), Positives = 217/511 (42%), Gaps = 50/511 (10%)
Query 507 VQPQVDASITQLILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIA 566
+QP+ + + ++ +EF +VL + DNFFD GGHS++AT++ + + + +
Sbjct 5896 IQPRNE--VEAVLCEEFSEVL-GVEVGVTDNFFDLGGHSLMATKLAARTGRRLDAKVSVK 5952
Query 567 DFFNAPTALELSQCVEYLSDRVKDSSVADDNREIVAPLTLLQKAFMGFSNQGRDAMYNIP 626
D F+ P +L+ ++ S + + + + F+ N + Y +P
Sbjct 5953 DVFDHPVLADLAAAIQRGSTPHSAIVTTEYSGPVEQSYAQGRLWFLEQLNF-KATWYLLP 6011
Query 627 FAFRFSETVNEQAFYDAFLDILKRHHVMRSIFVQADQGEIFQTVIPMDRLNQHPWFWGSE 686
A R +N +A A + +RH +R+ F++ D G Q V P ++
Sbjct 6012 LAVRIRGPLNIKALTTALHALEQRHETLRTTFIERD-GVGKQAVQPFQPKELEIVDIAAD 6070
Query 687 HQVGQSAQQILRAEANHSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMR 746
HQ ++LR E F+L + RV + +Q H LS++++HI D WS +L
Sbjct 6071 HQ--GDYLKVLRDEQTTMFNLATQPGWRVTLHRVDQNTHNLSIVMHHIISDGWSVDVLRH 6128
Query 747 ELIQAYTSRVDGKAP---------------IWEKTPRQFHEYAMAQDDSALQAHIQYWMN 791
EL Q Y + + G+ P +W+K P Q E+A ++YW
Sbjct 6129 ELRQFYAAALRGQDPLAHISPLPIQYRDFSLWQKQPDQIIEHA---------KQLEYWTK 6179
Query 792 TIGKIKKQQPLLPAYRNDVDMPPPENNLDDVSGAA--VEFNFTAIQVEQLYALARQYRSS 849
+ + LP D+P P +SG A V + E+L A + ++++
Sbjct 6180 QLADSSPAE--LP-----TDLPRPA----VLSGKAGEVALSVKGPLYERLQAFCKTHQTT 6228
Query 850 LFYVVYAGLLLTTYYLGAGKKVLSGTSVACRQDPNYQDTLGYFTNVVMHYIQFNESLSIK 909
F + A T + L + GT +A R P ++ +G+F N I + + +
Sbjct 6229 AFATLLAAFRATHHRLTGAEDATIGTPIANRNRPELENLIGFFVNAQCMRITIDGDETFE 6288
Query 910 DLVNQVQNNIFKAQEYADIPFAIVEDNIRAEGEEWTESP-YEVYVQLHAQNALTGVFQLN 968
L+ QV+ A D+PF + +++ + + +P ++ LH+Q L G QL
Sbjct 6289 SLIRQVRATATAAIANQDVPFERIVSTMQSTSRDTSRNPLVQLMFALHSQQDL-GKIQLE 6347
Query 969 SGDEIGFELIEPERDTAKFGLHFEVYEEPSS 999
+ P +F L F +Y+E S
Sbjct 6348 GCETEPI----PRAVRTRFDLEFHLYQEQGS 6374
Score = 123 bits (309), Expect = 2e-30
Identities = 118/496 (24%), Positives = 213/496 (43%), Gaps = 40/496 (8%)
Query 515 ITQLILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTA 574
I L+ +EF +VL + +D+FFD GGHS++AT++ + + + + D F+ P
Sbjct 8876 IEALLCEEFAEVL-GVEVGINDDFFDLGGHSLMATKLAARSSRRFDAKVSVKDVFDHPIL 8934
Query 575 LELSQCVEYLSDRVKDSSVADDNREIVAPLTLLQKAFMGFSNQGRDAMYNIPFAFRFSET 634
+L+ ++ S + + + F+ N Y P A R
Sbjct 8935 ADLAASIQRGSTPHNPILATQYSGPVEQSFAQGRLWFLEQLNVS-STWYLQPIAVRMRGP 8993
Query 635 VNEQAFYDAFLDILKRHHVMRSIFVQADQGEIFQTVIPMDRLNQHPWFWGSEHQVGQSAQ 694
+ +A AF + +RH +R+ F + D G Q V P +EH +
Sbjct 8994 LKIEALAAAFHALEERHETLRTTFEEHD-GIGMQVVQPHRPKELRVIDVQAEHDGDYT-- 9050
Query 695 QILRAEANHSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTS 754
Q L E +F+L E RV + + +ILS++++HI D WS IL +E+ + Y +
Sbjct 9051 QALHTEQTTTFNLETEPGWRVSVFRLNEDDNILSIVMHHIISDGWSFDILRKEIREFYNA 9110
Query 755 RVDGKAPIWEKTPRQFHEYAMAQDDSALQAHIQY-----WMNTIGKIKKQQPLLPAY-RN 808
+ GK P+ + +P HIQY W + +I + + L + +N
Sbjct 9111 ALKGKDPLAQMSP----------------LHIQYRDFSVWQKQLNQITEHKRQLDYWTKN 9154
Query 809 DVDMPPPENNLD-----DVSGAA--VEFNFTAIQVEQLYALARQYRSSLFYVVYAGLLLT 861
D P E D +SG A ++ + T ++L A R ++++LF V+ T
Sbjct 9155 LADNTPAELPTDLPRPAVLSGKAGVIQLSITGPVYDRLRAFCRVHQTTLFTVLLTVFRAT 9214
Query 862 TYYLGAGKKVLSGTSVACRQDPNYQDTLGYFTNVVMHYIQFNESLSIKDLVNQVQNNIFK 921
Y L + GT +A R P ++ +G+F N I E + + L++QV+
Sbjct 9215 HYRLTGAEDATIGTPIANRNRPELENLIGFFVNTQCMRITVEEEDTFETLIHQVRTTTTA 9274
Query 922 AQEYADIPFAIVEDNIRAEGEEWTESPY-EVYVQLHAQNALTGVFQLNSGDEIGFELIEP 980
A D+PF + + + + +P ++ +H+Q ++ + D + E I
Sbjct 9275 AFANQDVPFERIVSALLPGSRDTSRNPLSQIMFAVHSQKNISKI----ELDGLESEAISR 9330
Query 981 ERDTAKFGLHFEVYEE 996
T +F L F +++E
Sbjct 9331 ATST-RFDLEFHLFQE 9345
Score = 123 bits (308), Expect = 2e-30
Identities = 124/519 (24%), Positives = 212/519 (41%), Gaps = 35/519 (7%)
Query 523 FKQVLMNPN-LQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTALELSQCV 581
F+ + + PN + NFF+ GG SI A R++ + GLL+ I+D F P+ L +
Sbjct 802 FQSLGLKPNSTRHKSNFFNLGGDSIAAIRMVNMARAA-GLLLSISDIFQNPSLAGLINVM 860
Query 582 EYLSDRVKDSSVADDNREIVAPLTLLQKAFMGFSNQGRDAMYNIPFAFRFSETVNEQAFY 641
+ S + + + + F+ G + Y +P A R + QA
Sbjct 861 QQSSTAQDAIPATEYSGPVEQSFAQGRLWFLDQLTTGA-SWYLMPLAVRIHGPLRVQALS 919
Query 642 DAFLDILKRHHVMRSIFVQADQGEIFQTVIPMDRLNQHPWFWGSEHQVGQSAQQILRAEA 701
A + +RH +R+ F Q D G Q V P + + G Q+L+ E
Sbjct 920 SALHALEQRHETLRTTFEQQD-GMGVQIVHPSSKRELRVIDVSGKQNGGYD--QVLKREQ 976
Query 702 NHSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTSRVDGKAP 761
DL +E R ++ +HILS++++HI D WS G+L EL Y + + G P
Sbjct 977 TTPIDLAKEPGWRAALLRVGDDEHILSIVIHHIIYDGWSLGVLREELGDLYAAALRGPDP 1036
Query 762 IWEKTPR--QFHEYAM----AQDDSALQAHIQYWMNTIGKIKKQQPLLPAYRNDVDMPPP 815
+ P Q+ ++++ Q + Q + YW + + L D P P
Sbjct 1037 LAHMAPLPIQYRDFSVWQKQPQQVAQHQQQLVYWTKQLEDSAPAELL-------TDFPRP 1089
Query 816 ENNLDDVSGAAVEFNFT--AIQVEQLYALARQYRSSLFYVVYAGLLLTTYYLGAGKKVLS 873
++SG A E FT + L A R ++++ F V+ A Y L +
Sbjct 1090 A----ELSGRAGEVRFTIEGSVFDSLLAFRRVHQTTSFAVLLAVFRAAHYRLTGTEDATI 1145
Query 874 GTSVACRQDPNYQDTLGYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQEYADIPFAIV 933
GT +A R + +G+F N I + + LV+QV + A E+ D+PF +
Sbjct 1146 GTPIANRTRAEVEKLIGFFVNTQCMRIAVADDDTFASLVSQVWSVATAAFEHQDVPFERI 1205
Query 934 EDNIRAEGEEWTESPY-EVYVQLHAQNALTGVFQLNSGDEIGFELIEPERDTAKFGLHFE 992
+ + + +P ++ LH + L D+I E + E F+
Sbjct 1206 VSALLPGARDTSRNPLAQLLFALHLEQDL---------DKINLEGLACETVPTPMATRFD 1256
Query 993 VYEEPSSEKERLRVVINYRVNRYNEIQIQLIRQVAQQVL 1031
V E +RL V+N+ + + I + V Q++L
Sbjct 1257 VEFHLFQEDDRLNGVVNFSTDLFEPQTIHSLVSVFQEIL 1295
Score = 52.8 bits (125), Expect = 7e-09
Identities = 101/429 (24%), Positives = 165/429 (38%), Gaps = 52/429 (12%)
Query 40 NQIINIEKNG-VQLSFTEERAWMLHQQDPLASSGPFI--LAFRLSGEIEISRLSNAIQKL 96
N I+ +G V+ SF + R W L Q + A S +I +A R+ G + I L+ A+ L
Sbjct 7464 NPIVATPYSGPVEQSFAQGRLWFLDQLN--AGSLWYIQPIAVRVRGSLNIGALTTALNAL 7521
Query 97 YEGDSNLNLRYDLDDEGILNKYHDEHTPFEMNI--HVVKSEQEAVQYLLSWIQKPINLAK 154
+ L ++ + +GI + H P ++ I V + + ++ L Q NLA
Sbjct 7522 EKRHEPLRTTFE-EHDGIGVQVVQPHQPKKLRIVDTVANYQGDFIRALRKEQQTLFNLAT 7580
Query 155 APAIQFTLLPQSHHEVILGILGHHILLDDSAWQPIFAQLSQNYA--------QLDGVLTA 206
P + +LL + IL I+ HHI+ D + + L YA Q+D L
Sbjct 7581 EPGWRVSLLRIGEDDNILSIVMHHIISDGWSVDILRQDLKLFYAAALKSQEPQVD-ALPI 7639
Query 207 SNSHIELSSKIPAKVLVNSQNALQYW----KTIFPTGLNQLDWPKFCRAPNVQASIIQYG 262
K P +V Q L YW K P L D+P+ P V +
Sbjct 7640 QYRDFAFWQKQPEQV-AEHQRQLDYWIEQLKDSKPAEL-ITDFPR----PEVLSGTAGIV 7693
Query 263 QNTIFDYEQKAVRCSSSIPLKGLKQLSERAQASIFHTVVAQFGGYLNHLFGTQSIDLFVP 322
Q + +GL+ Q + F ++A F L GT+ + P
Sbjct 7694 QLAV-----------DGQVYEGLRAFCRIHQTTSFVVLLAAFRAAHYRLTGTEDATIGSP 7742
Query 323 IVEQYEASSLSQIRSSSNILPIRILRPEYSEQESNIENKEKESIVNVRNQILQGMVHNIS 382
I + S I N +RI+ E E ++ + NQ ++
Sbjct 7743 IANRNRPELESLIGFFVNTQCMRIMVGEDDTFERLVQQVRSTTTAAFANQ-------DVP 7795
Query 383 IEQILSATK-TKRNTIPNVLVTQFI-----DGSQFLKLEQVETSTLIIPPIHSDYDLTLA 436
E+I+S+ + T R+ N LV G ++LE VET I + + +D+
Sbjct 7796 FERIVSSVQSTSRDASRNPLVQLMFALHSQQGIGLMELEGVETEP-IARDVSTRFDIEFH 7854
Query 437 FQIKADEIH 445
K + +H
Sbjct 7855 LYQKEESLH 7863
Score = 51.6 bits (122), Expect = 1e-08
Identities = 52/195 (27%), Positives = 82/195 (42%), Gaps = 15/195 (8%)
Query 50 VQLSFTEERAWMLHQQDPLASSGPFILAFRLSGEIEISRLSNAIQKLYEGDSNLNLRYDL 109
V+ SF + R W L Q + AS LA RL G + + L+ A+ L + L ++
Sbjct 10032 VEQSFAQGRLWFLDQLNFGASWYLMPLALRLQGSLHVKSLTTALFALEQRHETLRTTFEE 10091
Query 110 DDEGILNKYHDEHTPFEMNIHVVKSEQEA--VQYLLSWIQKPINLAKAPAIQFTLLPQSH 167
D + H + ++ I V EQ + + L PI+L P + +L+
Sbjct 10092 QDGVGIQIVHPANKK-DLRILDVSKEQNSDYAKVLHKERTIPIDLTSEPGWRVSLIRLGE 10150
Query 168 HEVILGILGHHILLDDSAWQPIFAQLSQNY----------AQLDGVLTASNSHIELSSKI 217
+ IL I+ HHI+ D + + +L Q Y AQ+D L L K+
Sbjct 10151 DDHILSIVMHHIISDGWSVDVLRQELKQFYTAALKGQDPLAQID-ALPIQYRDFSLWQKL 10209
Query 218 PAKVLVNSQNALQYW 232
P +V Q L+YW
Sbjct 10210 PDQV-AEHQRQLEYW 10223
Score = 50.1 bits (118), Expect = 4e-08
Identities = 44/151 (29%), Positives = 66/151 (44%), Gaps = 3/151 (2%)
Query 50 VQLSFTEERAWMLHQQDPLASSGPFILAFRLSGEIEISRLSNAIQKLYEGDSNLNLRYDL 109
V+ SF + R W L Q AS LA R+ G + + LS+A+ L + L ++
Sbjct 879 VEQSFAQGRLWFLDQLTTGASWYLMPLAVRIHGPLRVQALSSALHALEQRHETLRTTFEQ 938
Query 110 DDEGILNKYHDEHTPFEMNIHVVKSEQEAV--QYLLSWIQKPINLAKAPAIQFTLLPQSH 167
D + H + E+ + V +Q Q L PI+LAK P + LL
Sbjct 939 QDGMGVQIVHPS-SKRELRVIDVSGKQNGGYDQVLKREQTTPIDLAKEPGWRAALLRVGD 997
Query 168 HEVILGILGHHILLDDSAWQPIFAQLSQNYA 198
E IL I+ HHI+ D + + +L YA
Sbjct 998 DEHILSIVIHHIIYDGWSLGVLREELGDLYA 1028
Score = 48.1 bits (113), Expect = 2e-07
Identities = 87/452 (19%), Positives = 179/452 (40%), Gaps = 69/452 (15%)
Query 522 EFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTALELSQCV 581
EF +VL + DNFFD GGHS+LAT++ ++ + + + D F+ P +L+ V
Sbjct 12507 EFAEVL-GVEVGITDNFFDLGGHSLLATKLAARISRRLDTRVSVKDVFDQPVPADLALKV 12565
Query 582 -EYLS------------------------------DRVKDSSVADDNREI--VAPLTLLQ 608
Y+S DR +A + +I V P+T +Q
Sbjct 12566 SSYISQGHAMDNGTLSTTNSIPFQLLHFEDSQKFIDRDIVPQLAHQSAKIVDVYPVTWIQ 12625
Query 609 KAFMGFSNQGRDAMYNIPFAFRFSETVNEQAFYDAFLDILKRHHVMRSIFVQADQGEIFQ 668
K F+ G ++ F F + +A +++ + R++FVQA G +Q
Sbjct 12626 KHFLVDPATGLPRTPSL-FFVDFPANADCDKICNASRSLIQLFDIFRTVFVQA-AGNFYQ 12683
Query 669 TVIPMDRLNQHPWFWGSEHQVGQSAQQILRAEANHSFDLMQEFPIRVRFMKDEQGQHILS 728
V ++ L+ P + + + + + + Q F +R +K ++
Sbjct 12684 VV--LEELD-IPISVIETEDISTATRVLKEQDQQNPLQFGQGF-LRFAVVKTRSAVRLV- 12738
Query 729 MLLYHIAMDEWSSGILMRELIQAYTSRVDGKAPIWEKTPRQ--FHEYAMAQDDSALQAHI 786
+ + H D G+ ++Q+ + +G ++ P Q F +Y DS + +
Sbjct 12739 LRISHCLYD----GLSFEHVVQSLHALYNG-----DRIPTQPKFVQYVQHLTDSRKEGY- 12788
Query 787 QYWMNTIGKIKKQQPLLPAYRNDVDMPPPENN--LDDVSGAAVEFNFTAIQVEQLYALAR 844
+W++ + + ++ R + PE ++ + A + N I ++ A
Sbjct 12789 DFWLSVLE--ESSMTVVETGRRAQQLSSPEGAWFVEKIIKAVIPANSDGITQATVFTTA- 12845
Query 845 QYRSSLFYVVYAGLLLTTYYLGAGKKVLSGTSVACRQDPNYQDTLGYFTNVVMHYIQFNE 904
S++ G T+ +++SG D Q +G TN+V I+ +
Sbjct 12846 ---STILLARMTGSSDITF-----SRLVSGRQSLPIND---QHIVGPCTNIVPVRIRMTD 12894
Query 905 SLSIKDLVNQVQNNIFKAQEYADIPFAIVEDN 936
+ ++L+ VQ+ + + + F +++N
Sbjct 12895 GTNARELLGMVQDQYIDSLPFETLGFDDIKEN 12926
Score = 47.0 bits (110), Expect = 4e-07
Identities = 84/375 (22%), Positives = 146/375 (39%), Gaps = 36/375 (10%)
Query 42 IINIEKNG-VQLSFTEERAWMLHQQDPLASSGPFILAFRLSGEIEISRLSNAIQKLYEGD 100
I+ E +G V+ S+ + R W L Q + A+ LA R+ G + I L+ A+ L +
Sbjct 5977 IVTTEYSGPVEQSYAQGRLWFLEQLNFKATWYLLPLAVRIRGPLNIKALTTALHALEQRH 6036
Query 101 SNLNLRYDLDDEGILNKYHDEHTPFEMNIHVVKSEQEA--VQYLLSWIQKPINLAKAPAI 158
L + ++ +G+ + P E+ I + ++ + ++ L NLA P
Sbjct 6037 ETLRTTF-IERDGVGKQAVQPFQPKELEIVDIAADHQGDYLKVLRDEQTTMFNLATQPGW 6095
Query 159 QFTLLPQSHHEVILGILGHHILLDDSAWQPIFAQLSQNY-AQLDG--------VLTASNS 209
+ TL + L I+ HHI+ D + + +L Q Y A L G L
Sbjct 6096 RVTLHRVDQNTHNLSIVMHHIISDGWSVDVLRHELRQFYAAALRGQDPLAHISPLPIQYR 6155
Query 210 HIELSSKIPAKVLVNSQNALQYWKTIFPTGLNQLDWPKFCRAPNVQASIIQYGQNTIFDY 269
L K P +++ +++ L+YW QL P + +
Sbjct 6156 DFSLWQKQPDQIIEHAKQ-LEYW-------TKQLADSSPAELPT------DLPRPAVLSG 6201
Query 270 EQKAVRCSSSIPL-KGLKQLSERAQASIFHTVVAQFGGYLNHLFGTQSIDLFVPIVEQYE 328
+ V S PL + L+ + Q + F T++A F + L G + + PI +
Sbjct 6202 KAGEVALSVKGPLYERLQAFCKTHQTTAFATLLAAFRATHHRLTGAEDATIGTPIANRNR 6261
Query 329 ASSLSQIRSSSNILPIRILRPEYSEQESNIENKEKESIVNVRNQILQGMVHNISIEQILS 388
+ I N +RI ES I + + NQ ++ E+I+S
Sbjct 6262 PELENLIGFFVNAQCMRITIDGDETFESLIRQVRATATAAIANQ-------DVPFERIVS 6314
Query 389 ATK-TKRNTIPNVLV 402
+ T R+T N LV
Sbjct 6315 TMQSTSRDTSRNPLV 6329
Score = 45.8 bits (107), Expect = 8e-07
Identities = 53/219 (24%), Positives = 88/219 (40%), Gaps = 17/219 (8%)
Query 25 LSERISTEAVEHYTENQIINIEKNG-VQLSFTEERAWMLHQQDPLASSGPFI-LAFRLSG 82
L+ I ++ H N I + +G V+ SF + R W L Q + S + LA RL G
Sbjct 11494 LAASIERNSIPH---NPIPSTNYSGPVEQSFAQGRLWFLDQLNMGVSELYLMPLALRLRG 11550
Query 83 EIEISRLSNAIQKLYEGDSNLNLRYDLDDEGILNKYHDEHTPFEMNIHVVKSEQEAVQYL 142
+ + + A+ L L + +D +G+ + ++ + + SE + + L
Sbjct 11551 PLRVDAFAAAVSALEARHETLRTTF-MDHDGVGMQVILPSNSKKLRV-IDASENDYIDIL 11608
Query 143 LSWIQKPINLAKAPAIQFTLLPQSHHEVILGILGHHILLDDSAWQPIFAQLSQNY-AQLD 201
P NL P + LL + IL I+ HHI+ D + + +L + Y A L
Sbjct 11609 RQERTAPFNLTTEPGFRIALLQLGQTDFILSIVMHHIIYDGWSIDVLCRELGRFYSAALQ 11668
Query 202 G--------VLTASNSHIELSSKIPAKVLVNSQNALQYW 232
G L + K P +V + LQYW
Sbjct 11669 GQDPLAQVSPLPIQYRDFSIWQKRPEQV-AEHERQLQYW 11706
>P0DUV4 Malpibaldin synthetase [Mortierella alpina]
Length=5541
Score = 127 bits (320), Expect = 8e-32
Identities = 121/507 (24%), Positives = 222/507 (44%), Gaps = 43/507 (8%)
Query 506 SVQPQVDASITQLILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKI 565
S Q +++ ++ ++ + +VL P + DNFF GGHS+LA R++ ++ T G + +
Sbjct 2001 SPQGRIECALAEI----WAEVLKVPRVGRHDNFFLLGGHSLLAVRLMNRISTL-GAQLPL 2055
Query 566 ADFFNAPTALELSQCVEYLSDRVKDSSVADDNREIVAPLTLLQKAFMGFSNQ-------- 617
+ F +PT +Q + S D + ++ ++ + + FS Q
Sbjct 2056 SALFASPTLSSFAQAFK------GQLSQDDQSHNVIPRVSRSEPLELSFSQQRLWFLAQM 2109
Query 618 -GRDAMYNIPFAFRFSETVNEQAFYDAFLDILKRHHVMRSIFVQADQGEIFQTVIPMDR- 675
G +Y+IP R T+N +A+ + RH +R++F Q + ++P D
Sbjct 2110 EGVSEIYHIPSVLRLRGTLNLEAWQRTLDTLFARHESLRTVFSTV-QSQPQIKILPADLG 2168
Query 676 --LNQHPWFWGSEHQVGQSAQQILRAEANHSFDLMQEFPIRVRFMKDEQGQHILSMLLYH 733
L H E S + + AEA FDL + IR + ++ +HI + +H
Sbjct 2169 LPLVHHDL--RGEQDKHASLKLLSAAEAIMPFDLERGPLIRAQLIQLTDDEHIFLLTQHH 2226
Query 734 IAMDEWSSGILMRELIQAYTSRVDGKAPIWEKTPRQFHEYAMAQ----DDSALQAHIQYW 789
I D WS GIL+REL + Y + +G Q+ +YA Q ++ L+A YW
Sbjct 2227 IVSDGWSFGILIRELRELYIAYRNGLPNPLRPLAIQYPDYAAWQRCWLNEGRLEAQSAYW 2286
Query 790 MNTIGKIKKQQPLLPAYRNDVDMPPPENNLDDVSGAAVEFNFTAIQVEQLYALARQYRSS 849
T+ + P+ D PP ++ +GA+V A + L AL++++ ++
Sbjct 2287 KKTLA----EAPVSIELPTDRPRPPQQS----FTGASVPVRVDAHVTQALKALSQKHGAT 2338
Query 850 LFYVVYAGLLLTTYYLGAGKKVLSGTSVACRQDPNYQDTLGYFTNVVMHYIQFNESLSIK 909
+F VV + L ++ G+ A R + +G+F N + + + +++
Sbjct 2339 MFMVVLSAWSAVLSRLSGQDDIVIGSPSANRGHEQVEQLIGFFVNTLALRVDLSGQPNME 2398
Query 910 DLVNQVQNNIFKAQEYADIPFAIVEDNIRAEGEEWTESPYEVYVQLHAQNALTGVFQLNS 969
L+ +V+ AQ + D+PF V + I ++P V QN + +L
Sbjct 2399 QLLKRVRETTVSAQAHQDLPFEQVVE-IAQPPRRMDQTPL-FQVLFAWQNNDIEMLRL-- 2454
Query 970 GDEIGFELIEPERDTAKFGLHFEVYEE 996
++ + E D KF L E+YE+
Sbjct 2455 -PDLDVTVEELSYDIVKFDLELELYED 2480
Score = 51.6 bits (122), Expect = 1e-08
Identities = 33/101 (33%), Positives = 53/101 (52%), Gaps = 8/101 (8%)
Query 504 TSSVQPQVDASITQLILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLI 563
TS P D I + + + ++L + DNFF GGHS+LA R+ G ++++ GL +
Sbjct 5215 TSYELPSGDVEIG--LAEIWAELLSLDRVGRHDNFFMLGGHSLLAVRMAGSVRSRLGLDL 5272
Query 564 KIADFFNAPTALELSQCVEYLSDRVKDSSVADDNREIVAPL 604
K+ F APT EL+Q + V+ + DD ++ PL
Sbjct 5273 KLHSLFAAPTVAELAQKL------VQGGANEDDEYSVIFPL 5307
Score = 48.1 bits (113), Expect = 2e-07
Identities = 84/443 (19%), Positives = 173/443 (39%), Gaps = 68/443 (15%)
Query 536 DNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTALELSQCVE-----YLSDRVKD 590
D+FF GGHS+L +++ +L + GL + + F +PT L+Q + + +
Sbjct 927 DSFFALGGHSLLVVKMLDRLH-RLGLTVSVRVLFESPTLSVLAQDLSKHQAMIIPPNLIT 985
Query 591 SSVADDNREIVAPLTLLQKAFMGFSNQGRDAMYNIPFAFR-------------------- 630
+ E++ + L Q +Q ++NI +
Sbjct 986 LETSKLTPEMLPLIDLKQDDIDRIISQVPGGIHNIQDVYSLAPLQDGILFHHLLAAEGDP 1045
Query 631 --------FSETVNEQAFYDAFLDILKRHHVMRSIFVQADQGEIFQTVIPMDRLNQHPWF 682
F + V + DAF ++ RH ++R+ Q V+ L+
Sbjct 1046 YLLISHLAFRDRVLVDRYLDAFQKVVDRHDILRTAVFWDALSTPAQVVLRSAPLSV---- 1101
Query 683 WGSEHQVGQSAQQI---LRAEANHS---FDLMQEFPIRVRFMKDEQGQHILSMLLYHIAM 736
+EH + +A + L NHS DL Q +R +D G+ I++ +++H+ +
Sbjct 1102 --TEHVLDPAAGPVADKLSQRYNHSKYRMDLTQAPLLRFALAEDIDGRWIMAQMMHHLII 1159
Query 737 DEWSSGILMRELIQAYTSRVDGKAPIWEKTPRQFHE-YAMAQDDSALQAHIQYWMNTIGK 795
D + ++ E+ R D + TP QF + A + + H ++ +G
Sbjct 1160 DHAAIEVMNAEVEAVLEGREDTLS-----TPPQFRDLVAQVRAGPTQEEHEHFFAEMLGD 1214
Query 796 IKKQQPLLPAYRNDVDMPPPENNLDDVSGAAVEFNFTAIQ--VEQLYALARQYRSSLFYV 853
I ++P P +V +N D+V E + T Q ++L A A++ +L +
Sbjct 1215 I--EEPTFPFGLTEV-----HSNGDEVK----EAHMTVPQDLNDRLRAQAKRLGVTLAAL 1263
Query 854 VYAGLLLTTYYLGAGKKVLSGTSV--ACRQDPNYQDTLGYFTNVVMHYIQFNESLSIKDL 911
+ V+ GT + + + + Q +G N + ++ S+++
Sbjct 1264 CHTAWAQVLARTSGQDHVVFGTVLVGGLQGEQSDQSGMGISINTLPFRCDMDDR-SVQEC 1322
Query 912 VNQVQNNIFKAQEYADIPFAIVE 934
V+Q+ + + E+ + A+ +
Sbjct 1323 VSQIHSRLAALVEHENASLALAQ 1345
Score = 42.7 bits (99), Expect = 7e-06
Identities = 85/415 (20%), Positives = 160/415 (39%), Gaps = 44/415 (11%)
Query 50 VQLSFTEERAWMLHQQDPLASSGPFILAFRLSGEIEISRLSNAIQKLYEGDSNLNLRYDL 109
++LSF+++R W L Q + ++ RL G + + + L+ +L +
Sbjct 2094 LELSFSQQRLWFLAQMEGVSEIYHIPSVLRLRGTLNLEAWQRTLDTLFARHESLRTVFST 2153
Query 110 DDEGILNKYHDEHTPFEMNIHVVKSEQE--AVQYLLSWIQ--KPINLAKAPAIQFTLLPQ 165
K + H ++ EQ+ A LLS + P +L + P I+ L+
Sbjct 2154 VQSQPQIKILPADLGLPLVHHDLRGEQDKHASLKLLSAAEAIMPFDLERGPLIRAQLIQL 2213
Query 166 SHHEVILGILGHHILLDDSAWQPIFAQLSQNY-AQLDGVLTASNSHIELSSKIPAKVL-- 222
+ E I + HHI+ D ++ + +L + Y A +G+ N L+ + P
Sbjct 2214 TDDEHIFLLTQHHIVSDGWSFGILIRELRELYIAYRNGL---PNPLRPLAIQYPDYAAWQ 2270
Query 223 --------VNSQNALQYWKTIFPTGLNQLDWPKFCRAPNVQASIIQYGQNTIFDYEQKAV 274
+ +Q+A YWK ++ P P Q+ F V
Sbjct 2271 RCWLNEGRLEAQSA--YWKKTLAEAPVSIELPTDRPRPPQQS----------FTGASVPV 2318
Query 275 RCSSSIPLKGLKQLSERAQASIFHTVVAQFGGYLNHLFGTQSIDLFVPIVEQYEASSLSQ 334
R + + + LK LS++ A++F V++ + L+ L G I + P +
Sbjct 2319 RVDAHV-TQALKALSQKHGATMFMVVLSAWSAVLSRLSGQDDIVIGSPSANRGHEQVEQL 2377
Query 335 IRSSSNILPIRILRPEYSEQESNIENKEKESIVNVRNQILQGMVH-NISIEQILSATKTK 393
I N L +R+ + S Q N+E + + VR + H ++ EQ++ +
Sbjct 2378 IGFFVNTLALRV---DLSGQ-PNME----QLLKRVRETTVSAQAHQDLPFEQVVEIAQPP 2429
Query 394 R----NTIPNVLVTQFIDGSQFLKLEQVETSTLIIPPIHSDYDLTLAFQIKADEI 444
R + VL + + L+L ++ + + +DL L DEI
Sbjct 2430 RRMDQTPLFQVLFAWQNNDIEMLRLPDLDVTVEELSYDIVKFDLELELYEDKDEI 2484
Score = 42.4 bits (98), Expect = 9e-06
Identities = 89/468 (19%), Positives = 175/468 (37%), Gaps = 88/468 (19%)
Query 523 FKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPT--------- 573
+ ++L + DNFF GGHS+LA ++IG+L+ + G ++ + F P
Sbjct 3071 WSELLKVDKIGRQDNFFMLGGHSLLAVQMIGQLR-RIGFVMSVRALFETPVLSVLAASIT 3129
Query 574 -----------------------------ALELSQ-CVEYLSDRVKDSSVADDNREIVAP 603
++LSQ ++ ++D++ N + +
Sbjct 3130 RGCEVPETPATPVNLITATTAKITPDLLPLIDLSQDDIDRITDQIPGGVA---NIQDIYS 3186
Query 604 LTLLQKAFMGFSNQG-RDAMYNIPFAFRFSETVNEQAFYDAFLDILKRHHVMRSIFVQAD 662
L+ LQ + D Y + F + + + DA I+ RH ++R+ V +
Sbjct 3187 LSPLQDGILFHHMMATEDDPYLLTICTAFRDRDLLERYLDAIQQIVDRHDILRTAIVWRN 3246
Query 663 QGEIFQTV-----IPMDRLNQHPWFWGSEHQVGQSAQQILRAEANHSFDLMQEFPIRVRF 717
Q V I + L P + + + +++ A H +L R
Sbjct 3247 MTTPAQVVLRKAAISVTELTLDP----ANSPIIEQLRKLYDAR-KHRIELDVAPLNRYAV 3301
Query 718 MKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTSRVDGKAPIWEKTPRQFHE-YAMA 776
+D G+ I+ +L+HI D + ++ E+ + ++ R + A P+ F A
Sbjct 3302 AQDTDGRWIMIQMLHHIVGDHSTLELMDEEIQKIFSGRGETLA-----APQPFRNLIAQV 3356
Query 777 QDDSALQAHIQYWMNTIGKIKKQQPLLPAYRNDVDMPPPENNLDDVSGAAVEFNFTAIQV 836
+ Q H +++ + +D+D P L DV T + +
Sbjct 3357 RSGLTFQEHEEFFSKML--------------SDIDAPALPYGLSDVHREGANVTETQLML 3402
Query 837 EQ-----LYALARQY---RSSLFYVVYAGLLLTTYYLGAGKKVLSGTSVACRQD--PNYQ 886
Q L + AR+ +SL ++ +A ++ T V+ GT + R
Sbjct 3403 PQKLNDRLRSQARRLGVSLASLCHLAWAQVIAAT---SGQYHVVFGTVLFGRMQGGSGAD 3459
Query 887 DTLGYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQEYADIPFAIVE 934
+G F N + + E SI + V++VQ ++ E+ A+ +
Sbjct 3460 RAMGLFINTLPLRVDV-EKGSILESVHKVQTDLATLLEHEHASLALAQ 3506
Score = 39.7 bits (91), Expect = 6e-05
Identities = 99/501 (20%), Positives = 191/501 (38%), Gaps = 98/501 (20%)
Query 496 DQEHWAQPTSSV-------QPQVDASITQLILDEFKQVLMNPNLQADDNFFDFGGHSILA 548
D+ H P +S P+ D I+ + + + +L + DNFF GGHS+LA
Sbjct 4121 DRRHLPAPDASAFVAQDYEAPRGDIEIS--LAEMWTDLLKIDQVGRHDNFFTLGGHSLLA 4178
Query 549 TRVIGKLQTQHGLLIKIADFFNAPT----------------------------------- 573
++I +L+ + GL + + F+ P
Sbjct 4179 VQMIEQLR-RIGLSLSVRALFDTPVLSVLAASLNTHQAAPETPANLITAATTVITPDLLP 4237
Query 574 ALELSQ-CVEYLSDRVKDSSVADDNREIVAPLTLLQKAFM---GFSNQGRDAMYNIPFAF 629
++L+Q ++ + D+V N + V L+ LQ + + +G + ++F
Sbjct 4238 LIDLTQGDIDCIVDQVPGGVA---NVQDVYSLSPLQDGILFHHMMATEGDPYLLIAGYSF 4294
Query 630 RFSETVNEQAFYDAFLDILKRHHVMRSIFVQAD-----QGEIFQTVIPMDRLNQHPWFWG 684
R E ++ + DA I+ RH ++R+ V + Q + + + + L P
Sbjct 4295 RDRELLDR--YLDAVQQIVDRHDILRTAIVSENLTVPAQVVLRKAPLSITELKLDP---- 4348
Query 685 SEHQVGQSAQQILRAEANHSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGIL 744
S+ + Q+ A + +L R +D G+ I+ LL+HI D + I+
Sbjct 4349 SDGAITSQLMQLYDAR-KYRIELRSAPLTRFIIAQDADGRWIMVQLLHHIIGDHSTLEIM 4407
Query 745 MRELIQAYTSRVDGKAPIWEKTPRQFHE-YAMAQDDSALQAHIQYWMNTIGKIKKQQPLL 803
E+ + + GKA P+ F A + +Q H +++ +
Sbjct 4408 DEEI----KTILGGKANTL-PAPQPFRNLVAQVRLGLTVQEHEEFFSKML---------- 4452
Query 804 PAYRNDVDMPPPENNLDDV--SGAAVEFNFTAIQVEQLYALARQYR------SSLFYVVY 855
+D+D P L DV GA V + L R + +SL ++ +
Sbjct 4453 ----SDIDTPALPYGLSDVHREGAGVTETHLMLPPNLNDRLRRHAKRLGVSPASLCHLAW 4508
Query 856 AGLLLTTYYLGAGKKVLSGTSVACRQD--PNYQDTLGYFTNVVMHYIQFNESLSIKDLVN 913
A ++ T + V+ GT + R T+G F N + + E+ ++ + V
Sbjct 4509 AQVIAAT---SGQRHVVFGTVLFGRMQGGSGADRTMGLFINTLPLRVDI-ENNTVLESVR 4564
Query 914 QVQNNIFKAQEYADIPFAIVE 934
+VQ ++ E+ A+ +
Sbjct 4565 KVQTDLATLLEHEHASLALAQ 4585
Score = 28.1 bits (61), Expect = 0.20
Identities = 59/303 (19%), Positives = 112/303 (37%), Gaps = 38/303 (13%)
Query 69 ASSGPFILAFRLS--GEIEISRLSNAIQKLYEGDSNLNLRYDLDDEGILNKYHDEHTPFE 126
A P++L L+ + + R +A QK+ + L D + P
Sbjct 1041 AEGDPYLLISHLAFRDRVLVDRYLDAFQKVVDRHDILRTAVFWDALSTPAQVVLRSAPLS 1100
Query 127 MNIHVVKSEQEAVQYLLSW----IQKPINLAKAPAIQFTLLPQSHHEVILGILGHHILLD 182
+ HV+ V LS + ++L +AP ++F L I+ + HH+++D
Sbjct 1101 VTEHVLDPAAGPVADKLSQRYNHSKYRMDLTQAPLLRFALAEDIDGRWIMAQMMHHLIID 1160
Query 183 DSAWQPIFAQLSQNYAQLDGVLTASNSHIELSSKIPAKVLVNSQNALQYWKTIFPTGLNQ 242
+A + + A++ + L+ +L +++ A + F L
Sbjct 1161 HAAIEVMNAEVEAVLEGREDTLSTPPQFRDLVAQVRAGPTQEEH------EHFFAEMLGD 1214
Query 243 LDWPKFCRAPNVQASIIQYGQNTIFDYEQKAVRCSSSIPLKGLKQLSERAQ------ASI 296
++ P F +G + + ++P +L +A+ A++
Sbjct 1215 IEEPTF-----------PFGLTEVHSNGDEVKEAHMTVPQDLNDRLRAQAKRLGVTLAAL 1263
Query 297 FHT----VVAQFGGYLNHLFGTQSIDLFVPIVEQYEASSLSQIRSSSNILPIRILRPEYS 352
HT V+A+ G + +FGT + Q E S S + S N LP R + S
Sbjct 1264 CHTAWAQVLARTSGQDHVVFGTVLVGGL-----QGEQSDQSGMGISINTLPFRCDMDDRS 1318
Query 353 EQE 355
QE
Sbjct 1319 VQE 1321
>Q00869 N-methylcyclopeptide synthetase / S-adenosyl-L-methionine-dependent
N-methyltransferase [Fusarium equiseti]
Length=3131
Score = 124 bits (312), Expect = 7e-31
Identities = 130/535 (24%), Positives = 232/535 (43%), Gaps = 44/535 (8%)
Query 538 FFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTALELSQCVEYLSDRVKDSSVADDN 597
FF+ GG+SI+A +++ ++ +G+ +K++D + PT L V + + S +
Sbjct 1040 FFEMGGNSIIAIKMVNMARS-NGIELKVSDIYQNPTLAGLKAIV--IGTSLPYSLIPKVT 1096
Query 598 REIVAPLTLLQKAFMGFSNQGRD--AMYNIPFAFRFSETVNEQAFYDAFLDILKRHHVMR 655
R+ + M F +Q + + Y IPFA R V+ A A L + +RH +R
Sbjct 1097 RQGPVSEQSYAQNRMWFLDQLSEGASWYLIPFAVRMRGPVDVDALTRALLALEQRHETLR 1156
Query 656 SIFVQADQGEIFQTVIPMDRLNQHPWFWGSEHQVGQSAQQILRAEANHSFDLMQEFPIRV 715
+ F D + I DRL++ + + + + E +FD+ E
Sbjct 1157 TTFENQDGVGV---QIIHDRLSKELQVIDALDGDEGGLKTLYKVETT-TFDITSEAGWSS 1212
Query 716 RFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTSRVDGKAPIWEKTPR--QFHEY 773
++ + HILS++++HI D WS +L RELIQ Y + + GK P TP Q+ ++
Sbjct 1213 TLIRLGKDDHILSIVMHHIISDGWSIDVLRRELIQLYAAALQGKDPSSALTPLPIQYSDF 1272
Query 774 AMAQDDSALQA----HIQYWMNTIGKIKKQQPLLPAYRNDVDMPPPENNLDDVSGAAVEF 829
A+ Q A A +QYW KKQ + D P P+ D V
Sbjct 1273 AVWQKQEAQAAEHERQLQYW-------KKQLADSSPAKIPTDFPRPDLLSGDAGVVPVAI 1325
Query 830 NFTAIQVEQLYALARQYRSSLFYVVYAGLLLTTYYLGAGKKVLSGTSVACRQDPNYQDTL 889
+ Q +L ++ S+ F ++ A Y L A + G +A R ++ +
Sbjct 1326 DGELYQ--KLRGFCNKHNSTAFSILLAAFRAAHYRLTAVDDAVIGIPIANRNRWELENMI 1383
Query 890 GYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQEYADIPFAIVEDNIRAEGEEWTESPY 949
G+F N I +E+ + + LV QV++ A + D+PF V ++ + + +P
Sbjct 1384 GFFVNTQCMRIAVDETDTFESLVRQVRSTTTAAFAHEDVPFERVVSALQPGHRDLSRTPL 1443
Query 950 -EVYVQLHAQNALTGVFQLNSGDEIGFELIEPERDTAKFGLHFEVYEEPSSEKERLRVVI 1008
++ +H+Q L G F+L E I+ E +K F+V + + L+
Sbjct 1444 AQIMFAVHSQKDL-GRFEL--------EGIQSEPIASKAYTRFDVEFHLFQQADGLKGSC 1494
Query 1009 NYRVNRYNEIQIQLIRQVAQQVLE----------SFIHIDTQSEECTQIDVMEIR 1053
N+ + + IQ + V Q+L S + + EE ++D++EI+
Sbjct 1495 NFATDLFKPETIQNVVSVFFQILRHGLDQPETCISVLPLTDGVEELRRLDLLEIK 1549
Score = 49.3 bits (116), Expect = 7e-08
Identities = 118/578 (20%), Positives = 230/578 (40%), Gaps = 77/578 (13%)
Query 494 GSDQEHWAQPTSSVQPQVDASITQLILDEFKQVLMNPNLQADDNFFDFGGHSILATRV-- 551
G D++ W+ S V P+ + + +++ +EF L P + DNFFD GGHS++AT++
Sbjct 2587 GQDKQGWS---SRVAPRTE--VEKMLCEEFAAGLGVP-VGITDNFFDLGGHSLMATKLAV 2640
Query 552 -IG----------------------KLQTQH-------GLLIKIADFFNAPTALELSQCV 581
IG KL++ H G I++AD + A L+L
Sbjct 2641 RIGRRLIRHHSQGHLRLPCAFQLAKKLESSHSKSYEESGDDIQMAD-YTAFQLLDLEDPQ 2699
Query 582 EYLSDRVKDS-SVADDNREIVAPLTLLQKAFMGFSNQGRDAMYNIPFAFRFSETVNEQAF 640
+++ +++ + V P T +QKAF+ F + +PF F + +
Sbjct 2700 DFVQSQIRPQLDSCYGTIQDVYPSTQMQKAFL-FDPTTGEPRGLVPFYIDFPSNADAETL 2758
Query 641 YDAFLDILKRHHVMRSIFVQADQGEIFQTVIPMDRLNQHPWFWGSEHQVGQSAQQILRAE 700
A ++ + + R++F++A G+++Q V+ + LN +E V + L
Sbjct 2759 TKAIGALVDKLDMFRTVFLEA-AGDLYQVVV--EHLNLPIETIETEKNVNTATGDYLDVH 2815
Query 701 ANHSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTSRVDGKA 760
L I+ +K +L + + H D S ++R L Y+ R
Sbjct 2816 GKDPVRLGHPC-IQFAILKTASSVRVL-LRMSHALYDGLSFEYIVRGLHVLYSGR---NL 2870
Query 761 PIWEKTPRQFHEYAMAQDDSALQAHIQYWMNTIGKIKKQQPLLPAYRNDVDMPPPENNLD 820
P P QF Y S + + +W ++ + P+ + + M E
Sbjct 2871 P----PPTQFARYMQYAAHSREEGY-PFWR----EVLQNAPMTVLHDTNNGMSEQEM--- 2918
Query 821 DVSGAAVEFNFTAIQVEQLYALARQYRSSLFYVVYAGLLLTTYYLGAGKKVLSGTSVACR 880
+ AV + Q + ++++F A +L + V+ G V+ R
Sbjct 2919 -PASKAVHLSEVVNVPAQAIRNSTNTQATVFNTACALVLAKE---SGSQDVVFGRIVSGR 2974
Query 881 Q--DPNYQDTLGYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQEYADIPFAIVEDNIR 938
Q +QD +G TN V + + ++ + + ++ +++ + + + F ++ N
Sbjct 2975 QGLPVVWQDIIGPCTNAVPVHARVDDG-NPQRIIRDLRDQYLRTLPFESLGFEEIKRNCT 3033
Query 939 AEGEEWTESPYEVYVQLHAQNALTGVFQLNSGDEIGF--ELIEPERDTAKFGLHFEVYEE 996
EE T + V V H N E+G + +E + + L + E
Sbjct 3034 DWPEELTN--FSVCVTYHNFEYHPESEVDNQKVEMGVLAKYVELSENEPLYDL--AIAGE 3089
Query 997 PSSEKERLRVVINYRVNRYNEIQIQLIRQVAQQVLESF 1034
++ L+V + + YNE + IR V ++V ++F
Sbjct 3090 VEADGVNLKVTVVAKARLYNEAR---IRHVLEEVCKTF 3124
Score = 47.0 bits (110), Expect = 4e-07
Identities = 28/111 (25%), Positives = 55/111 (50%), Gaps = 3/111 (3%)
Query 502 QPTSSVQPQVDASITQLILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGL 561
Q T++ P S ++ L E + ++ D+FF GGHS+LAT++I ++Q + +
Sbjct 2495 QQTAAPVPDFPISDIEITLCEEATEVFGMKVEISDHFFQLGGHSLLATKLISRIQHRLHV 2554
Query 562 LIKIADFFNAPTALELSQCVEY---LSDRVKDSSVADDNREIVAPLTLLQK 609
+ + D F++P +L+ + + + V + VAP T ++K
Sbjct 2555 RVTVKDVFDSPVFADLAVIIRQGLAMQNPVAEGQDKQGWSSRVAPRTEVEK 2605
Score = 41.2 bits (95), Expect = 2e-05
Identities = 43/190 (23%), Positives = 73/190 (38%), Gaps = 10/190 (5%)
Query 53 SFTEERAWMLHQQDPLASSGPFILAFRLSGEIEISRLSNAIQKLYEGDSNLNLRYDLDDE 112
S+ + R W L Q AS A R+ G +++ L+ A+ L + L ++ D
Sbjct 1105 SYAQNRMWFLDQLSEGASWYLIPFAVRMRGPVDVDALTRALLALEQRHETLRTTFENQDG 1164
Query 113 GILNKYHDEHTPFEMNIHVVKSEQEAVQYLLSWIQKPINLAKAPAIQFTLLPQSHHEVIL 172
+ HD + I + ++ ++ L ++ TL+ + IL
Sbjct 1165 VGVQIIHDRLSKELQVIDALDGDEGGLKTLYKVETTTFDITSEAGWSSTLIRLGKDDHIL 1224
Query 173 GILGHHILLDDSAWQPIFAQLSQNY-AQLDG--------VLTASNSHIELSSKIPAKVLV 223
I+ HHI+ D + + +L Q Y A L G L S + K A+
Sbjct 1225 SIVMHHIISDGWSIDVLRRELIQLYAAALQGKDPSSALTPLPIQYSDFAVWQKQEAQA-A 1283
Query 224 NSQNALQYWK 233
+ LQYWK
Sbjct 1284 EHERQLQYWK 1293
>A0A0A1EA36 Nonribosomal peptide synthetase / S-adenosyl-L-methionine-dependent
N-methyltransferase [Fusarium oxysporum]
Length=3132
Score = 124 bits (312), Expect = 7e-31
Identities = 130/535 (24%), Positives = 232/535 (43%), Gaps = 44/535 (8%)
Query 538 FFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTALELSQCVEYLSDRVKDSSVADDN 597
FF+ GG+SI+A +++ ++ +G+ +K++D + PT L V + + S +
Sbjct 1040 FFEMGGNSIIAIKMVNMARS-NGIELKVSDIYQNPTLAGLKAIV--IGTSLPYSLIPKVT 1096
Query 598 REIVAPLTLLQKAFMGFSNQGRD--AMYNIPFAFRFSETVNEQAFYDAFLDILKRHHVMR 655
R+ + M F +Q + + Y IPFA R V+ A A L + +RH +R
Sbjct 1097 RQGPVSEQSYAQNRMWFLDQLSEGASWYLIPFAVRMRGPVDVDALTRALLALEQRHETLR 1156
Query 656 SIFVQADQGEIFQTVIPMDRLNQHPWFWGSEHQVGQSAQQILRAEANHSFDLMQEFPIRV 715
+ F D + I DRL++ + + + + E +FD+ E
Sbjct 1157 TTFENQDGVGV---QIIHDRLSKELQVIDALDGDEGGLKTLYKVETT-TFDITSEAGWSS 1212
Query 716 RFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTSRVDGKAPIWEKTPR--QFHEY 773
++ + HILS++++HI D WS +L RELIQ Y + + GK P TP Q+ ++
Sbjct 1213 TLIRLGKDDHILSIVMHHIISDGWSIDVLRRELIQLYAAALQGKDPSSALTPLPIQYSDF 1272
Query 774 AMAQDDSALQA----HIQYWMNTIGKIKKQQPLLPAYRNDVDMPPPENNLDDVSGAAVEF 829
A+ Q A A +QYW KKQ + D P P+ D V
Sbjct 1273 AVWQKQEAQAAEHERQLQYW-------KKQLADSSPAKIPTDFPRPDLLSGDAGVVPVAI 1325
Query 830 NFTAIQVEQLYALARQYRSSLFYVVYAGLLLTTYYLGAGKKVLSGTSVACRQDPNYQDTL 889
+ Q +L ++ S+ F ++ A Y L A + G +A R ++ +
Sbjct 1326 DGELYQ--KLRGFCNKHNSTAFSILLAAFRAAHYRLTAVDDAVIGIPIANRNRWELENMI 1383
Query 890 GYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQEYADIPFAIVEDNIRAEGEEWTESPY 949
G+F N I +E+ + + LV QV++ A + D+PF V ++ + + +P
Sbjct 1384 GFFVNTQCMRIAVDETDTFESLVRQVRSTTTAAFAHEDVPFERVVSALQPGHRDLSRTPL 1443
Query 950 -EVYVQLHAQNALTGVFQLNSGDEIGFELIEPERDTAKFGLHFEVYEEPSSEKERLRVVI 1008
++ +H+Q L G F+L E I+ E +K F+V + + L+
Sbjct 1444 AQIMFAVHSQKDL-GRFEL--------EGIQSEPIASKAYTRFDVEFHLFQQADGLKGSC 1494
Query 1009 NYRVNRYNEIQIQLIRQVAQQVLE----------SFIHIDTQSEECTQIDVMEIR 1053
N+ + + IQ + V Q+L S + + EE ++D++EI+
Sbjct 1495 NFATDLFKPETIQNVVSVFFQILRHGLDQPETCISVLPLTDGVEELRRLDLLEIK 1549
Score = 55.5 bits (132), Expect = 1e-09
Identities = 115/578 (20%), Positives = 226/578 (39%), Gaps = 76/578 (13%)
Query 494 GSDQEHWAQPTSSVQPQVDASITQLILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIG 553
G D++ W+ S V P+ + + +++ +EF L P + DNFFD GGHS++AT++
Sbjct 2587 GQDKQGWS---SRVAPRTE--VEKMLCEEFAAGLGVP-VGITDNFFDLGGHSLMATKLAV 2640
Query 554 KLQTQHGLLIKIADFFNAPTALELS------------------QCVEYLSDRVKDSSVAD 595
++ + I + D F+ P +L+ Q +Y + ++ D
Sbjct 2641 RIGRRLDTAITVKDIFDYPVLFQLAKKLESSHSKSYEESGDDIQMADYTAFQLLDLEDPQ 2700
Query 596 D---------------NREIVAPLTLLQKAFMGFSNQGRDAMYNIPFAFRFSETVNEQAF 640
D + V P T +QKAF+ F + +PF F + +
Sbjct 2701 DFVQSQIRPQLDSCYGTIQDVYPSTQMQKAFL-FDPTTGEPRGLVPFYIDFPSNADAETL 2759
Query 641 YDAFLDILKRHHVMRSIFVQADQGEIFQTVIPMDRLNQHPWFWGSEHQVGQSAQQILRAE 700
A ++ + + R++F++A G+++Q V+ + LN +E V + L
Sbjct 2760 TKAIGALVDKLDMFRTVFLEA-AGDLYQVVV--EHLNLPIETIETEKNVNTATGDYLDVH 2816
Query 701 ANHSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTSRVDGKA 760
L I+ +K +L + + H D S ++R L Y+ R
Sbjct 2817 GKDPVRLGHPC-IQFAILKTASSVRVL-LRMSHALYDGLSFEYIVRGLHVLYSGR---NL 2871
Query 761 PIWEKTPRQFHEYAMAQDDSALQAHIQYWMNTIGKIKKQQPLLPAYRNDVDMPPPENNLD 820
P P QF Y S + + +W ++ + P+ + + M E
Sbjct 2872 P----PPTQFARYMQYAAHSREEGY-PFWR----EVLQNAPMTVLHDTNNGMSEQEM--- 2919
Query 821 DVSGAAVEFNFTAIQVEQLYALARQYRSSLFYVVYAGLLLTTYYLGAGKKVLSGTSVACR 880
+ AV + Q + ++++F A +L + V+ G V+ R
Sbjct 2920 -PASKAVHLSEVVNVPAQAIRNSTNTQATVFNTACALVLAKE---SGSQDVVFGRIVSGR 2975
Query 881 Q--DPNYQDTLGYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQEYADIPFAIVEDNIR 938
Q +QD +G TN V + + ++ + + ++ +++ + + + F ++ N
Sbjct 2976 QGLPVVWQDIIGPCTNAVPVHARVDDG-NPQRIIRDLRDQYLRTLPFESLGFEEIKRNCT 3034
Query 939 AEGEEWTESPYEVYVQLHAQNALTGVFQLNSGDEIGF--ELIEPERDTAKFGLHFEVYEE 996
EE T + V V H N E+G + +E + + L + E
Sbjct 3035 DWPEELTN--FSVCVTYHNFEYHPESEVDNQKVEMGVLAKYVELSENEPLYDL--AIAGE 3090
Query 997 PSSEKERLRVVINYRVNRYNEIQIQLIRQVAQQVLESF 1034
++ L+V + + YNE + IR V ++V ++F
Sbjct 3091 VEADGVNLKVTVVAKARLYNEAR---IRHVLEEVCKTF 3125
Score = 47.0 bits (110), Expect = 4e-07
Identities = 28/111 (25%), Positives = 55/111 (50%), Gaps = 3/111 (3%)
Query 502 QPTSSVQPQVDASITQLILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGL 561
Q T++ P S ++ L E + ++ D+FF GGHS+LAT++I ++Q + +
Sbjct 2495 QQTAAPVPDFPISDIEITLCEEATEVFGMKVEISDHFFQLGGHSLLATKLISRIQHRLHV 2554
Query 562 LIKIADFFNAPTALELSQCVEY---LSDRVKDSSVADDNREIVAPLTLLQK 609
+ + D F++P +L+ + + + V + VAP T ++K
Sbjct 2555 RVTVKDVFDSPVFADLAVIIRQGLAMQNPVAEGQDKQGWSSRVAPRTEVEK 2605
Score = 41.2 bits (95), Expect = 2e-05
Identities = 43/190 (23%), Positives = 73/190 (38%), Gaps = 10/190 (5%)
Query 53 SFTEERAWMLHQQDPLASSGPFILAFRLSGEIEISRLSNAIQKLYEGDSNLNLRYDLDDE 112
S+ + R W L Q AS A R+ G +++ L+ A+ L + L ++ D
Sbjct 1105 SYAQNRMWFLDQLSEGASWYLIPFAVRMRGPVDVDALTRALLALEQRHETLRTTFENQDG 1164
Query 113 GILNKYHDEHTPFEMNIHVVKSEQEAVQYLLSWIQKPINLAKAPAIQFTLLPQSHHEVIL 172
+ HD + I + ++ ++ L ++ TL+ + IL
Sbjct 1165 VGVQIIHDRLSKELQVIDALDGDEGGLKTLYKVETTTFDITSEAGWSSTLIRLGKDDHIL 1224
Query 173 GILGHHILLDDSAWQPIFAQLSQNY-AQLDG--------VLTASNSHIELSSKIPAKVLV 223
I+ HHI+ D + + +L Q Y A L G L S + K A+
Sbjct 1225 SIVMHHIISDGWSIDVLRRELIQLYAAALQGKDPSSALTPLPIQYSDFAVWQKQEAQA-A 1283
Query 224 NSQNALQYWK 233
+ LQYWK
Sbjct 1284 EHERQLQYWK 1293
>C7ZBE4 Nonribosomal peptide synthetase 30 [Fusarium vanettenii
(strain ATCC MYA-4622 / CBS 123669 / FGSC 9596 / NRRL 45880
/ 77-13-4)]
Length=5911
Score = 120 bits (300), Expect = 2e-29
Identities = 130/548 (24%), Positives = 229/548 (42%), Gaps = 56/548 (10%)
Query 479 EEAAIFAFGHQASPYGSDQEHWAQ------PTSSVQPQVDASITQLILDEFKQVLMNPNL 532
E + F+F H A Q+ + PT+ ++ Q+ A +++ + +
Sbjct 4219 EIGSSFSFQHLAEVANQVQDDENETKARRPPTTPLECQMQAIWVRIL------GISPDRI 4272
Query 533 QADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTALELSQCVEYLSDRVKDSS 592
DD+F GG SI A +V+G+ + L I +AD P ++ +
Sbjct 4273 SLDDSFIRLGGDSIAAMKVVGEARKHGSLDITVADLLRRPKLCDIIATMTKNKATGASRR 4332
Query 593 VADDNREIVAPLTLLQKAFMGFSNQGR----DAMYN------IPFAFRFSETVNEQAFYD 642
+ D+ E + ++ QGR D +Y +PF RF + A +
Sbjct 4333 LPRDDDEPIPHTKYAGPVDQSYA-QGRLWFLDRLYPGLTWCLMPFTARFRGILRLDALHI 4391
Query 643 AFLDILKRHHVMRSIFVQADQGEI--FQTVIPMD-RLNQHPWFWGSEHQVGQSAQQILRA 699
A + RH +R+ F+ D ++ IP + +L + P E +S Q+ L
Sbjct 4392 ALQAVENRHEALRTTFMSRDNVDLQEIHPFIPRELKLVELPRGAKGE----ESLQRALFK 4447
Query 700 EANHSFDLMQEFPIRV---RFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTSRV 756
E DL E RV R +E+ H+LS+L++HI D WS +L REL Y + V
Sbjct 4448 ERTTPLDLSTETGWRVTVYRLGPEEENHHVLSILMHHIISDGWSLNVLRRELDIFYAAAV 4507
Query 757 DGKAPI--WEKTPRQFHEYAMAQ----DDSALQAHIQYWMNTIGKIKKQQPLLPAYRNDV 810
+ P+ + P Q+ +YA Q Q + YW++ + + + L
Sbjct 4508 NSLDPLSQIDPLPIQYRDYASWQKQRFHQDEYQRQLDYWVSQLQTSRPAEFL-------C 4560
Query 811 DMPPPENNLDDVSGAA--VEFNFTAIQVEQLYALARQYRSSLFYVVYAGLLLTTYYLGAG 868
D P P D +SG A EF ++L + + F V+ A T + L
Sbjct 4561 DKPRP----DTLSGGAGVHEFTIANTMYDRLQKFCAEAEVTPFVVLLAAFRATHFRLTGV 4616
Query 869 KKVLSGTSVACRQDPNYQDTLGYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQEYADI 928
GT+ A R ++ +G+F N+ I+ + +S +DLV QVQ + + +
Sbjct 4617 DDATIGTANANRDRWEVKELIGFFVNLQCLRIKMEQGVSFEDLVQQVQETAAASFDNQHV 4676
Query 929 PFAIVEDNIRAEGEEWTESPYEVYVQLHAQNALTGVFQLNSGDEIGFELIEPERDTAKFG 988
PF + + + +V LH++ +G +L GD++ E+++P T++F
Sbjct 4677 PFEKIVSQLNTPRDLSRHPLVQVIFALHSRGT-SGPVKL--GDDLESEMLDP-IPTSQFD 4732
Query 989 LHFEVYEE 996
L F V+++
Sbjct 4733 LEFHVFDD 4740
Score = 56.2 bits (134), Expect = 6e-10
Identities = 66/303 (22%), Positives = 110/303 (36%), Gaps = 39/303 (13%)
Query 535 DDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTALELSQCV------------- 581
+D+FF GG SI A +V+ + Q + + +AD P E + V
Sbjct 918 NDSFFQLGGDSISAMKVVRDAREQLEVELSVADILQHPRLSEAAAIVARGTKLFKSDEVP 977
Query 582 ------------EYLSDRVKDSSVADDNREIVAPLTLLQK--AFMGFSNQGRDAMYNIPF 627
E + +K V + E P T LQ+ F+ + G D +
Sbjct 978 AAFSLLPGNNAREAIDPALKSHGVQSLSVEDAFPCTPLQEGLVFLSLKSPG-DYIMQTTL 1036
Query 628 AFRFSETVNEQAFYDAFLDILKRHHVMRSIFVQADQGEIFQTVIPMDRLNQHPWFWGSEH 687
S N F A+ ++ H +R+ FV +D +T + L + W
Sbjct 1037 DLSTSSYSNAHKFRQAWEHVVAEHPALRTRFVHSDG----ETGLAQVVLRPEAFAW--NE 1090
Query 688 QVGQSAQQILRAEANHSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRE 747
S + L + L Q F R + D+ ++H D WS ++M
Sbjct 1091 VANSSLNEYLETDRRQPMSLGQAF-ARCALVHDKGAPRWFVWTMHHALYDGWSIRLIMNA 1149
Query 748 LIQAYTSRVDGKAPIWEKTPRQ---FHEYAMAQDDSALQAHIQYWMNTIGKIKKQQ-PLL 803
+AY S G + T F +Y ++Q SA + +YW T+ + Q P +
Sbjct 1150 FQRAYRSLEAGSNLVTGTTNASYPAFIKYILSQSVSADGSMAKYWKKTLSDCEAAQFPAV 1209
Query 804 PAY 806
P +
Sbjct 1210 PLH 1212
Score = 44.7 bits (104), Expect = 2e-06
Identities = 81/414 (20%), Positives = 165/414 (40%), Gaps = 66/414 (16%)
Query 502 QPTSSVQPQVDASITQLILDEFKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGL 561
QPTS ++ ++ +++ E +++ + DD+FF GG SI A + +G+ T+ +
Sbjct 2001 QPTSELEAEMQQIWARVLSFEPERIGL------DDSFFRLGGDSIAAMKAVGE-ATKASI 2053
Query 562 LIKIADFFNAPTALELSQCVEYLSDRVKDS-SVADDNREIVAP--LTLLQKAFMGFSNQG 618
+ +ADFF T + Y S+ +S S+A ++ ++AP + +K G + Q
Sbjct 2054 RVTVADFFEHRTLRNICSHSYYCSEMAAESLSIAVESFSLLAPDSIETREKLVQGLAAQL 2113
Query 619 RDAMYNIPFAF---------------RFSETVNEQ-------------AFYDAFLDILKR 650
R I A+ R + + +Q F DA+ +
Sbjct 2114 RTTTSRIQDAYPCTPLQEGLVSLASKRTGDYIMQQVLELSPDMLNNIDTFKDAWQKAVHA 2173
Query 651 HHVMRSIFVQADQGEIFQTVIPMDRLNQHPWFWGSEHQVGQSAQQILRAEANHSFDLMQE 710
V+R+ VQ ++ + Q + LN G E L+++ L Q
Sbjct 2174 VPVLRTRIVQHEKLGLLQVL-----LNHQD--EGIEWTEAMGLDWYLKSDRQKPMGLGQP 2226
Query 711 FPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTSRVDGKAPIWEKTPRQ- 769
R ++D G+ + H A+ + G+ + +++ + G++ + Q
Sbjct 2227 L-ARYALVRDRTGRPKWFVWTVHHALYD---GLSLPMILEEVDRTMQGQSVEQARPQAQA 2282
Query 770 FHEYAMAQDDSALQAHIQYWMNTIGKIKKQQPLLPAYRNDVDMPPPENNLDDVSGAAVEF 829
F +Y D + L++ YW T+G + P+ + ++ P NNL +
Sbjct 2283 FIKYIQQHDSNELKS---YWQATLGD-SGECVSYPSLPSGLERPIMSNNLIE-------- 2330
Query 830 NFTAIQVEQLYALARQYRSSLFYVVYAGLLLTTYYLGAGKKVLSGTSVACRQDP 883
Q+ + + + +++ ++ A L T + V+ G +V+ R P
Sbjct 2331 ----HQIPRAWVSSSSNETTVSTMLRAAWGLVTSQMTGSDDVVFGATVSGRNAP 2380
Score = 40.4 bits (93), Expect = 4e-05
Identities = 22/56 (39%), Positives = 34/56 (61%), Gaps = 8/56 (14%)
Query 535 DDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTALELSQCVEYLSDRVKD 590
DDNFFD GGHSILA R + + + + + + +AD F S+C+E L+ R ++
Sbjct 5387 DDNFFDIGGHSILAMRAVSEAR-KVDIELTVADIFR-------SKCLEALARRQEE 5434
Score = 35.4 bits (80), Expect = 0.001
Identities = 33/124 (27%), Positives = 60/124 (48%), Gaps = 14/124 (11%)
Query 484 FAFGHQASPYGSDQEHWAQPTSSVQPQVDASITQLILDEFKQVLMNPNLQADDNFFDFGG 543
FA + G+ + QP+++ Q ++ I ILD L + DD FF GG
Sbjct 3094 FAAARKTREQGTPSQE--QPSTNAQRELQ-QIWSRILD-----LPTDLIGLDDGFFSLGG 3145
Query 544 HSILATRVIGKLQTQHGLLIKIADFFNAPTALELSQCVEYLSDRVKDSSVADDNREIVAP 603
S+ A +V+G+ + + G+ + +AD F T ++ + + R D +VA+ I+ P
Sbjct 3146 DSVSAMKVVGEAR-KAGIELAVADIFTHRTLRLIADNSKSIK-REGDQTVAN----IIPP 3199
Query 604 LTLL 607
+L+
Sbjct 3200 FSLI 3203
>P39847 ATP-dependent glutamate adenylase 2 / ATP-dependent alanine/valine
adenylase [Bacillus subtilis (strain 168)]
Length=2555
Score = 116 bits (291), Expect = 2e-28
Identities = 122/537 (23%), Positives = 225/537 (42%), Gaps = 52/537 (10%)
Query 514 SITQLILDE-FKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAP 572
++T++ L + ++ VL N + DNFFD GGHS+ AT ++ ++ + + + + D F P
Sbjct 970 NVTEMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRIAKEFDVQVPLKDVFAHP 1029
Query 573 TALELSQCVEYLSDRVKDSSVADDNREIVAPLTLLQKAFMGFSNQGRDAMYNIPFAFRFS 632
T L+ + +D ++ + +E + ++ ++ + YN+P
Sbjct 1030 TVEGLATVIREGTDSPYEAIKPAEKQETYPVSSAQKRIYVLQQLEDGGTGYNMPAVLELE 1089
Query 633 ETVNEQAFYDAFLDILKRHHVMRSIFVQADQGEIFQTVIPMDRLNQHPWFWGSEHQVGQS 692
+N + AF +++KRH +R+ F Q G+ P+ R++ F +G
Sbjct 1090 GKLNLERMDRAFKELIKRHESLRTAFEQDAGGD------PVQRIHDEVPFTLQTTVLGAR 1143
Query 693 AQQILRAEANHSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAY 752
++ A FDL Q R + +K +H+L + ++HI D S IL+RE + Y
Sbjct 1144 TEEEAAAAFIKPFDLSQAPLFRAQIVKVSDERHLLLVDMHHIISDGVSVNILIREFGELY 1203
Query 753 TSRVDGKAPIWEKTPRQFHEYAMAQD----DSALQAHIQYWMNTIGKIKKQQPL--LPAY 806
+R K P Q+ +YA+ Q+ A + YW+ +++ + P+ LPA
Sbjct 1204 NNR---KLPALR---IQYKDYAVWQEGFKTGDAYKTQGAYWLK---QLEGELPVLDLPA- 1253
Query 807 RNDVDMPPPENNLDDVSGAAVEFNFTAIQVEQLYALARQYRSSLFYVVYAGLLLTTYYLG 866
D PP + +G V F LY LAR+ S+L+ V+ A L
Sbjct 1254 --DHARPP----MRSFAGDKVSFTLDQEVTSGLYKLARENGSTLYMVLLAAYTAFLSRLS 1307
Query 867 AGKKVLSGTSVACRQDPNYQDTLGYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQEYA 926
+ ++ G+ +A R + + LG F N + + + +V+ +A E+
Sbjct 1308 GQEDIIVGSPIAGRPHKDLEPILGMFVNTLALRTRPEGGKPFVQYLQEVRETAMEAFEHQ 1367
Query 927 DIPFAIVEDNIRAEGEEWTESPYEVYVQLHAQNALTGVFQLNSGDEIGFELIE------- 979
D PF + D + + ++V +F L + D+ EL E
Sbjct 1368 DYPFEELVDKLELTRDMSRNPLFDV------------MFVLQNMDQESLELDELCLKPAA 1415
Query 980 -PERDTAKFGLHFEVYEEPSSEKERLRVVINYRVNRYNEIQIQLIRQVAQQVLESFI 1035
T+KF L E+P + L + + + Y + I+ Q +L S I
Sbjct 1416 NNGHQTSKFDLTLYAQEQP---RGLLTFQMEFSTDLYKKKTIEKWLQYFNNMLLSII 1469
Score = 55.8 bits (133), Expect = 7e-10
Identities = 64/338 (19%), Positives = 145/338 (43%), Gaps = 25/338 (7%)
Query 601 VAPLTLLQKAFMGFSNQGRDAM-YNIPFAFRFSETVNEQAFYDAFLDILKRHHVMRSIFV 659
+ PL+ +Q+ + S + Y +F ++ + F + + R+ + R+ F+
Sbjct 10 IYPLSFMQEGMLFHSLYDEQSRAYFEQASFTIHGQLDLERFQKSMDAVFDRYDIFRTAFI 69
Query 660 QADQGEIFQTVIPMDRLNQHPWFWG--SEHQVGQSAQQILRAEANHSFDLMQEFPIRVRF 717
+ + Q V+ H +E + + + FDL + +R+
Sbjct 70 YKNVAKPRQVVLKQRHCPIHIEDISHLNERDKEHCTEAFKEQDKSKGFDLQTDVLMRISI 129
Query 718 MKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTSRVDGKAPIWEKTPRQ----FHEY 773
+K ++ +HI MD W GI++++ + Y + G+ P + P Q + ++
Sbjct 130 LKWAPDHYVCIWSHHHILMDGWCLGIVIKDFLHIYQALGKGQLP--DLPPVQPYGTYIKW 187
Query 774 AMAQDDSALQAHIQYWMNTIGKIKKQQPLLPAYRNDVDMPPPENNLDDVSGAAVEFNFTA 833
M QD + +YW + +K P LP + + P L ++ A E
Sbjct 188 LMQQD---REEAAEYWKKRLQHFEKSTP-LPKRTDQI----PNGTLQQITFAIPEKE--T 237
Query 834 IQVEQLYALARQYRSSLFYVVYAGLLLTTYYLGAGKKVLSGTSVACRQD--PNYQDTLGY 891
+++++ A + +++F ++ G++L + + G+ ++ R + ++ +G
Sbjct 238 AELQKIAAASGATLNTVFQALW-GIMLQK--VNRSSDAVFGSVISGRPSELKDVENMVGL 294
Query 892 FTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQEYADIP 929
F N + Q ++SLS DLV ++Q ++ +A+ Y+ P
Sbjct 295 FINTIPIRAQ-SDSLSFSDLVRRMQKDMNEAEAYSYFP 331
Score = 55.5 bits (132), Expect = 9e-10
Identities = 114/566 (20%), Positives = 216/566 (38%), Gaps = 69/566 (12%)
Query 523 FKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTALELSQCVE 582
+++VL + +D+FF+ GG SI A +V +L ++GL ++++D F P +LS +
Sbjct 2016 WQEVLGIQRIGIEDSFFELGGDSIKALQVSARL-GRYGLSLQVSDLFRHPKIKDLSPFIR 2074
Query 583 YLSDRVKDSSVADDNREIVAPLTLLQKAFMGFSNQGRDAMYNIPFAFRFSETVNEQAFYD 642
++ + D P T +Q+ F + R +N S ++E A
Sbjct 2075 KSERIIEQGPIQGD-----VPWTPVQQWFFSQDIEERH-HFNQSVMLFHSGRLSENALRP 2128
Query 643 AFLDILKRHHVMRSIF-------VQADQG--EIFQTVIPMDRLNQHPWFWGSEHQVGQSA 693
A + + H +R ++ +Q +QG E + + L+Q W E ++ Q
Sbjct 2129 ALKKLAEHHDALRMVYRNDDRRWIQINQGIHESQLYSLRISDLSQSESGW--ETKIKQEV 2186
Query 694 QQILRAEANHSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAY- 752
A+ S +L + + K G + L + ++H+ +D S IL+ +L Y
Sbjct 2187 -----ADLQQSINLQEGPLLHAALFKTLTGDY-LFLAIHHLVVDGVSWRILLEDLSAGYQ 2240
Query 753 ------TSRVDGKAPIWEKTPRQFHEYAMAQDDSALQAHIQYWMNTIGKIKKQQPLLPAY 806
T ++ K +++ R+ EYA + S L YW + +++QQ Y
Sbjct 2241 QAAAGQTIQLPPKTDSYQEYARRIQEYAQS---SKLIREEAYWRS----VEEQQAAELPY 2293
Query 807 RNDVDMPPPENNLDDVSGAAVEFNFT-AIQVEQLYALARQYRSSLFYVVYAGLLLTTYYL 865
P N+D ++ F+ T A L + Y + ++ L
Sbjct 2294 E-----IPHHVNIDFSKRDSLSFSLTEADTAVLLQNVNHAYGTDTQDILLTAASLAICEW 2348
Query 866 GAGKKVLSGTSVACRQ----DPNYQDTLGYFTNVVMHYIQFNES--------LSIKDLVN 913
G K+ R+ + + T+G+FT++ I F ++KD +
Sbjct 2349 TGGSKLRIAMEGHGREHILPELDISRTVGWFTSMYPALISFENHRDELGTSVKTVKDTLG 2408
Query 914 QVQNNIFKAQEYADIPFAIVEDNIRAEGEEWTESPYEVYVQLH--AQNALTGVFQLNSGD 971
++ N K Y + + +N + E + Q + + L SG
Sbjct 2409 RIPN---KGVGYGMLKYLTHPENKSITFSKTPEISFNYLGQFNDIERQDTFRPSSLGSGK 2465
Query 972 EIGF-----ELIEPERDTAKFGLHFEVYEEPSSEKERLRVVINYRVNRYNEIQIQLIRQV 1026
+I ++IE A LHF + P+ R + +NR + +++
Sbjct 2466 DITHTWKREQIIEMSAMAADKKLHFNLSYPPARFH---RNTMEQLINRIEHFLLDIMKHC 2522
Query 1027 AQQVLESFIHIDTQSEECTQIDVMEI 1052
A Q D S+ T D+ I
Sbjct 2523 AGQQKAEKTLSDFSSQSLTAEDLDSI 2548
Score = 54.7 bits (130), Expect = 2e-09
Identities = 87/434 (20%), Positives = 176/434 (41%), Gaps = 45/434 (10%)
Query 52 LSFTEERAWMLHQQDPLASSGPFILAFRLSGEIEISRLSNAIQKLYEGDSNLNLRYDLDD 111
+S ++R ++L Q + + L G++ + R+ A ++L + +L ++ D
Sbjct 1060 VSSAQKRIYVLQQLEDGGTGYNMPAVLELEGKLNLERMDRAFKELIKRHESLRTAFEQDA 1119
Query 112 EGI-LNKYHDEHTPFEMNIHVV--KSEQEAVQYLLSWIQKPINLAKAPAIQFTLLPQSHH 168
G + + HDE PF + V+ ++E+EA + KP +L++AP + ++ S
Sbjct 1120 GGDPVQRIHDE-VPFTLQTTVLGARTEEEAAAAFI----KPFDLSQAPLFRAQIVKVSDE 1174
Query 169 EVILGILGHHILLDDSAWQPIFAQLSQ--NYAQLDGVLTASNSHIELSSKIPAKVLVNSQ 226
+L + HHI+ D + + + + N +L + + +Q
Sbjct 1175 RHLLLVDMHHIISDGVSVNILIREFGELYNNRKLPALRIQYKDYAVWQEGFKTGDAYKTQ 1234
Query 227 NALQYWKTIFPTGLNQLDWPKFCRAPNVQASIIQYGQNTIFDYEQKAVRCSSSIPLKGLK 286
A YW L LD P P +++ G F +Q+ GL
Sbjct 1235 GA--YWLKQLEGELPVLDLPADHARPPMRSFA---GDKVSFTLDQEVT--------SGLY 1281
Query 287 QLSERAQASIFHTVVAQFGGYLNHLFGTQSIDLFVPIVEQYEASSLSQIRSSSNILPIRI 346
+L+ ++++ ++A + +L+ L G + I + PI + + N L +R
Sbjct 1282 KLARENGSTLYMVLLAAYTAFLSRLSGQEDIIVGSPIAGRPHKDLEPILGMFVNTLALR- 1340
Query 347 LRPEYSEQESNIENKEKESIVNVRNQILQGMVH-NISIEQILSATKTKRNTIPNVLV-TQ 404
RPE + + + VR ++ H + E+++ + R+ N L
Sbjct 1341 TRPEGGK-------PFVQYLQEVRETAMEAFEHQDYPFEELVDKLELTRDMSRNPLFDVM 1393
Query 405 FIDGSQFLKLEQVETSTLIIPPI------HSDYDLTL-AFQIKADEIHFELTTGEKLSKK 457
F+ Q + E +E L + P S +DLTL A + + F++ L KK
Sbjct 1394 FV--LQNMDQESLELDELCLKPAANNGHQTSKFDLTLYAQEQPRGLLTFQMEFSTDLYKK 1451
Query 458 IGLLLLEQWIEFLH 471
+E+W+++ +
Sbjct 1452 ---KTIEKWLQYFN 1462
Score = 35.0 bits (79), Expect = 0.002
Identities = 28/125 (22%), Positives = 56/125 (45%), Gaps = 7/125 (6%)
Query 81 SGEIEISRLSNAIQKLYEGDSNLNLRYDLDDEGIL--NKYHDEHTPFEMNIHVVKSEQEA 138
SG + + L A++KL E L + Y DD + N+ E + + I + +
Sbjct 2118 SGRLSENALRPALKKLAEHHDALRMVYRNDDRRWIQINQGIHESQLYSLRISDLSQSESG 2177
Query 139 ----VQYLLSWIQKPINLAKAPAIQFTLLPQSHHEVILGILGHHILLDDSAWQPIFAQLS 194
++ ++ +Q+ INL + P + L + + + HH+++D +W+ + LS
Sbjct 2178 WETKIKQEVADLQQSINLQEGPLLHAALFKTLTGDYLFLAI-HHLVVDGVSWRILLEDLS 2236
Query 195 QNYAQ 199
Y Q
Sbjct 2237 AGYQQ 2241
Score = 23.9 bits (50), Expect = 3.8
Identities = 11/38 (29%), Positives = 22/38 (58%), Gaps = 2/38 (5%)
Query 1020 IQLIRQVAQQVLESFIHIDTQSEECTQIDVMEIRHQLS 1057
+Q +++V + +E+F H D EE +D +E+ +S
Sbjct 1350 VQYLQEVRETAMEAFEHQDYPFEEL--VDKLELTRDMS 1385
>O68008 ATP-dependent isoleucine adenylase / ATP-dependent D-phenylalanine
adenylase / ATP-dependent histidine adenylase /
ATP-dependent D-aspartate adenylase / ATP-dependent asparagine
adenylase / Aspartate racemase / Phenylalanine racemase
[ATP hydrolyzing] [Bacillus licheniformis]
Length=6359
Score = 116 bits (291), Expect = 2e-28
Identities = 105/504 (21%), Positives = 203/504 (40%), Gaps = 36/504 (7%)
Query 523 FKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTALELSQCVE 582
++ VL N+ NFF+ GGHS+ A + KL + + + + F PT ++ +E
Sbjct 3510 WEDVLGIENIGISHNFFELGGHSLKAAALTAKLHKEMKIEVPLRQLFETPTIKDIGDFIE 3569
Query 583 YLSDRVKDSSVADDNREIVAPLTLLQKAFMGFSNQGRDAMYNIPFAFRFSETVNEQAFYD 642
+ + S + +E A + ++ ++ + YN+PFA + + + F D
Sbjct 3570 SMKESPYASITQAEEKEYYALSSAQRRLYILNQIEPGGLSYNMPFAMKIAGDFDVDRFED 3629
Query 643 AFLDILKRHHVMRSIFVQADQGEIFQTVIPMDRLNQHPWFWGSEHQVGQSAQQILRAEAN 702
AF +++RH +R+ FV D GE P+ ++ + F ++GQ +
Sbjct 3630 AFRQLIERHEALRTAFVMVD-GE------PVQKIEKEVDFKVKYGRLGQDPLEEKIKAFI 3682
Query 703 HSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTSRVDGKAPI 762
F L + +R +K +H+L + ++HI D S I REL + Y + I
Sbjct 3683 KPFALEKAPLLRAEVLKASGDEHVLMLDMHHIISDGVSMAIFTRELAELYEGKTLPPLTI 3742
Query 763 WEKTPRQFHEYAMAQDDSALQAHIQYWMNTIGKIKKQQPLLPAYRNDVDMPPPENNLDDV 822
K ++ + +D+ Q YW+N Q +P D P+ +
Sbjct 3743 QYKDFSEWQKLFYQKDEVKRQE--DYWLNVF------QGEVPVLNLPADEKRPQKR--SI 3792
Query 823 SGAAVEFNFTAIQVEQLYALARQYRSSLFYVVYAGLLLTTYYLGAGKKVLSGTSVACRQD 882
G V+F L LA++ ++++ ++ AG + ++ G+ +A R
Sbjct 3793 EGDIVQFEIDGETSAMLNKLAKENGATMYMLLLAGYTTLLAKYTGQEDIVVGSPIAGRHH 3852
Query 883 PNYQDTLGYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQEYADIPFAIVEDNIRAEGE 942
+ + +G F N + + D + +V+ KA E D PF + + + + +
Sbjct 3853 SDLKHVIGLFINTLAMRNHPKGDMPFADYLKEVKETALKAYENQDYPFDELVEKLDVKRD 3912
Query 943 EWTESPYEVYVQLHAQNALTGVFQLNSGDE-----IGFELIEPERDTAKFGLHFEVYEEP 997
++ + V Q GDE + F+ ++ E + +KF L E
Sbjct 3913 MSRHPLFDTML----------VLQNFDGDEADIDGLTFQPLQTEVNISKFDLTLTAAE-- 3960
Query 998 SSEKERLRVVINYRVNRYNEIQIQ 1021
E ++ V NY + I+
Sbjct 3961 --TNEGIQCVFNYSTKLFKRSTIE 3982
Score = 101 bits (251), Expect = 1e-23
Identities = 98/472 (21%), Positives = 198/472 (42%), Gaps = 38/472 (8%)
Query 535 DDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTALELSQCVEYLSDRVKDSSVA 594
+D+FF+ GGHS+ A + +++ + I + F PT L + + D V S
Sbjct 986 NDHFFEMGGHSLKAAAMAARIRKELKAEIPLGQIFKTPTIKGLGEYIRSTKDSVYSSIQK 1045
Query 595 DDNREIVAPLTLLQKAFMGFSNQGRDAMYNIPFAFRFSETVNEQAFYDAFLDILKRHHVM 654
+ +E + ++ ++ +G YNIPF + + + F +A I++RH +
Sbjct 1046 VEEKEYYRLSSAQKRLYILDQIEGSGLSYNIPFTMKVKGRFDIRRFENALKTIIQRHEAL 1105
Query 655 RSIFVQADQGEIFQTVIPMDRLNQHPWFWGSEHQVGQSAQQILRAEANHSFDLMQEFPIR 714
R+ F+ AD GE P+ ++ + F ++ + Q + + FDL + R
Sbjct 1106 RTSFLMAD-GE------PVQKIEKEVDFSIKCSKIQSLSIQEIIKQFVRPFDLKKAPLFR 1158
Query 715 VRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTSRVDGKAPIWEKTPRQFHEYA 774
+K + +HI+ ++HI D S G+L +E+ Y + + Q+ +Y+
Sbjct 1159 TEVVKVDDEEHIILFDMHHIISDGASMGVLTKEICDLYGGKE------LKPLSLQYKDYS 1212
Query 775 MAQDD----SALQAHIQYWMNTIGKIKKQQPLLPAYRNDVDMPPPENNLDDVSGAAVEFN 830
Q D ++ +YW+N + +P D P P+ + V G + F
Sbjct 1213 EWQRDFYQKDEMKRQKEYWLNIF------KGEIPVLNMPTDYPRPQ--MHSVEGDRIGFA 1264
Query 831 FTAIQVEQLYALARQYRSSLFYVVYAG--LLLTTYYLGAGKKVLSGTSVACRQDPNYQDT 888
++L +A+ ++++ ++ A +LL TY + V+ GT + R+ +
Sbjct 1265 IDGELTKKLKRIAKDNGATMYMLLLAAYTVLLRTY--SGQEDVIIGTPIQGRKHHELKHV 1322
Query 889 LGYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQEYADIPFAIVEDNIRAEGEEWTESP 948
+G F N + + + + V+ KA E D F + + + E + + +P
Sbjct 1323 IGMFVNTLAMRNHPKGDKTFAEYLQDVKETALKAYENQDYQFDDLVEQLDLE-RDMSRNP 1381
Query 949 Y--EVYVQLHAQNALTGVFQLNSGDEIGFELIEPERDTAKFGLHFEVYEEPS 998
++V + + A + + + FE E + +KF L E+ S
Sbjct 1382 LFDTMFVLQNLEKADAEI------EGLTFEPFESDIHISKFDLTLSAIEKDS 1427
Score = 82.8 bits (203), Expect = 5e-18
Identities = 111/462 (24%), Positives = 187/462 (40%), Gaps = 51/462 (11%)
Query 599 EIVAPLTLLQKAFMGFSNQGRDAM-YNIPFAFRFSETVNEQAFYDAFLDILKRHHVMRSI 657
E + PL +Q+ + + + +++ Y A ++E+ F + F DI++RH ++R+
Sbjct 5089 EKIYPLANMQRGMLFHALEDKESQAYFEQMAINMKGLIDERLFAETFNDIMERHEILRAS 5148
Query 658 FVQADQGEIFQTVIPMDR---LNQHPWFWGSEHQVGQSAQQILRAEANHSFDLMQEFPIR 714
++ + + + VI DR L+ H S + Q Q +A+ F L E IR
Sbjct 5149 -IEYEITDEPRNVIIKDRKINLDYHDLRKQSPAEREQVIQAYRKADREKGFRLNSEPLIR 5207
Query 715 VRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTSRVDGKAPIWEKTPRQFHEY- 773
M+ E + +HI +D WS GI+M EL Y + + E+ R + +Y
Sbjct 5208 AALMRTEDDSYTFIWTNHHILLDGWSRGIIMGELFHMYHMKEARQKHRLEEA-RPYSDYI 5266
Query 774 --AMAQDDSALQAHIQYWMNTIGKIKKQQPL---------LPAYRNDVDMPPPENNLDDV 822
QD A +A YW N + ++ P+ R + + PE +
Sbjct 5267 GWLQQQDKEAAKA---YWRNYLSGFTEKSPISVLAGSSGHAKYKRKEAVIEFPEQLTGRI 5323
Query 823 SGAAVEFNFTAIQVEQLYALARQYRSSLFYVVYAGLLLTTYYLGAGKKVLSGTSVACR-- 880
+ A N T V Q G+LL Y V+ GT ++ R
Sbjct 5324 TELASRNNVTFHTVLQ---------------CIWGMLLARY--NQTDDVVFGTVISGRDA 5366
Query 881 QDPNYQDTLGYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQEYADIPFAIVEDNIRAE 940
Q + +G F N V I+ ++S S K+L+ VQ + + Y D+ + V+ +
Sbjct 5367 QVTGIEKMVGLFINTVPTRIRLDKSQSFKELIKSVQEQALEGRTYHDMNLSEVQSLSELK 5426
Query 941 GEEWTE-SPYEVYVQLHAQNALTGVFQLNSGDEIGFELIEPERDTAKFGLHFEVYEEPSS 999
E +E Y + +G G FE I E T +G F + P
Sbjct 5427 RELLDHILIFENYAVDQSAFETSG----KRGAGFVFEEIHAEEQT-NYG--FNIVAVPG- 5478
Query 1000 EKERLRVVINYRVNRYNEIQIQLIRQVAQQVLESFIHIDTQS 1041
ERL + + Y N Y++ I I+ QQV+E + + QS
Sbjct 5479 --ERLVIKLTYDGNIYHDHIIAGIKGHLQQVMEQVVQHEDQS 5518
Score = 78.2 bits (191), Expect = 1e-16
Identities = 85/348 (24%), Positives = 143/348 (41%), Gaps = 28/348 (8%)
Query 599 EIVAPLTLLQKA--FMGFSNQGRDAMYNIPFAFRFSETVNEQAFYDAFLDILKRHHVMRS 656
E + PL +QK F + DA + V+ +F DI+KRH ++R+
Sbjct 2542 EKIYPLANMQKGMLFHAIEDHTSDAYFQ-QTVMDIEGYVDPAILEASFNDIMKRHEILRA 2600
Query 657 IFVQADQGEIFQTVIPMDRLNQHPWF---WGSEHQVGQSAQQILRAEANHSFDLMQEFPI 713
+ E Q +I +R +F S Q +++L + FDL ++ +
Sbjct 2601 SYEYEIVEEPRQIIIE-NRSIDFTYFNIAKSSAQQQEMFIERLLNEDRKKGFDLSKDVLM 2659
Query 714 RVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTSRVDGKA-PIWEKTPRQFHE 772
R +K + + L +HI +D W GI+MREL Y +R++GKA P+ E P + +
Sbjct 2660 RAYLLKTAERSYRLVWSHHHILLDGWCLGIIMRELFVIYENRMNGKASPLKETKP--YSD 2717
Query 773 YAMAQDDSALQAHIQYWMNTIGKIKKQQPLLPAYRNDVDMP--PPENNLDDVSGAAVEFN 830
Y + + QYW + L Y +P +
Sbjct 2718 YIKWLERQDQEEARQYW----------REYLKGYEEQAQLPTLTKRKKSSRYDRREKVIH 2767
Query 831 FTAIQVEQLYALARQYRSSLFYVVYA--GLLLTTYYLGAGKKVLSGTSVACRQD--PNYQ 886
+ +QL LA + +L V+ GL+LT Y V+ GT V+ R+ +
Sbjct 2768 LSKQLTKQLKELAAKNSVTLHTVIQTIWGLMLTRY--TKIDDVVFGTVVSGREANVDGIE 2825
Query 887 DTLGYFTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQEYADIPFAIVE 934
D +G F N + I+FNE D + +VQ + ++ Y + A V+
Sbjct 2826 DMIGLFINTIPTRIRFNEQARFNDCLQKVQEDAIQSNRYNYMNLAEVQ 2873
Score = 72.8 bits (177), Expect = 5e-15
Identities = 82/338 (24%), Positives = 148/338 (44%), Gaps = 35/338 (10%)
Query 467 IEFLHLDAQQRLEEAAIFAFGHQASPYGSDQEHWAQPTSSVQPQVDASITQLILDEFKQV 526
IE + L A +++ AA+ P + + P + + + ++ +++V
Sbjct 4510 IEKMPLSANGKIDTAAL------PEPQPGKETEYEPPRNETEEK--------LVQIWEEV 4555
Query 527 LMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTALELSQCVEYLSD 586
L + +FF GG SI A ++I +L ++ GL +++ D F P LS+ V+ SD
Sbjct 4556 LGIDKIGITHHFFAAGGDSIKALQMISRL-SREGLSLEMKDLFANPQIKSLSRYVKAESD 4614
Query 587 RVKDSSVADDNREIVAPLTLLQKAFMGFSNQGRDAMYNIPFAFRFSETVNEQAFYDAFLD 646
K +S E++ LT +Q+ + + R+ YN +E F +
Sbjct 4615 --KSASYETVEGEVL--LTPIQQEYFSLNKTDRN-HYNHAVMLYRKNGFDESIVKRVFKE 4669
Query 647 ILKRHHVMRSIFVQADQGEIFQTVIPMDR--LNQHPWFWGSEHQVGQSAQQILRAEANHS 704
I+K H +R++F + D G+I Q D+ + + SE+ Q Q L E S
Sbjct 4670 IIKHHDALRTVFTEED-GKIIQYNRGPDKQLFDLFVYDVSSENDQPQKVYQ-LATELQQS 4727
Query 705 FDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTSRVDG-KAPIW 763
D+ +++ K G H+L ++++H+ +D S IL +L Y+ +G K +
Sbjct 4728 IDIETGPLVKLAVFKTNNGDHLL-IIIHHLVVDGISWRILFEDLAIGYSQLANGEKVEFY 4786
Query 764 EKT------PRQFHEYAMAQDDSALQAHIQYWMNTIGK 795
KT R EYA + L + QYW+ I +
Sbjct 4787 PKTASYQAYARHIAEYAKS---VKLLSEKQYWLKAIAE 4821
Score = 64.7 bits (156), Expect = 2e-12
Identities = 92/465 (20%), Positives = 188/465 (40%), Gaps = 33/465 (7%)
Query 599 EIVAPLTLLQKA--FMGFSNQGRDAMYNIPFAFRFSETVNEQAFYDAFLDILKRHHVMRS 656
E + PL+ +QK F ++ A + F V+E+ F ++ +++KRH ++R+
Sbjct 6 EKIYPLSNMQKGMLFHAMKDEASHAYFE-QFIIELKGDVDERMFEESLNEVMKRHEILRA 64
Query 657 IFVQADQGEIFQTVIPMDRLNQHPWF-WGSEHQVGQSAQQILRAEANHSFDLMQEFPIRV 715
F + VI DR + + H ++ L + FDL ++ +R
Sbjct 65 SFHHRLDEPLH--VIIKDRHMKFDYLDIRGRHDQDGVLERYLAEDRQKGFDLAKDTLMRA 122
Query 716 RFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTSRVDGKAPIWEKTPRQFHEYAM 775
++ + +HI +D W GI++ EL+ Y + G+ E PR + +Y
Sbjct 123 CLIRMSDDSYQFVWTYHHILLDGWCLGIILDELLTIYEMKRKGQNHQLE-DPRPYSDYIK 181
Query 776 AQDDSALQAHIQYWMNTIGKIKKQQPLLPAYRNDVDMPPPENNLDDVSGAAVEFNFTAIQ 835
+D + YW + + Q+ LP R P E +
Sbjct 182 WLEDQDKEEAQSYWESYLSGY-DQKNSLPKLRT-----PSETGF---KRREKTIECSKEL 232
Query 836 VEQLYALARQYRSSLFYVVYA--GLLLTTYYLGAGKKVLSGTSVACR--QDPNYQDTLGY 891
+L LA + ++ V+ + G++L Y + V+ GT V+ R + + +G
Sbjct 233 TNRLIKLANRNHVTINTVLQSIWGVILAKY--NNSEDVVFGTVVSGRDAEVEGIETMVGV 290
Query 892 FTNVVMHYIQFNESLSIKDLVNQVQNNIFKAQEYADIPFAIVEDNIRAEGEEWTESPYEV 951
F N + I+ ++ KD++ Q Q + ++ Y + A ++A E + V
Sbjct 291 FINTIPTRIRLDKDKLFKDVLRQTQADALESSRYNYMNLA----EVQALSELKNDLIDHV 346
Query 952 YVQLHAQNALTGVFQLNSGDEIGFELIEPERDTAKFGLHFEVYEEPSSEKERLRVVINYR 1011
V +N +++GFE++ + + HF + ++ ++L+++ Y
Sbjct 347 MV---FENYAVDQKAFEEKNDVGFEMVNVSGE-EQTNYHFSI---SAALDDQLKLLFIYD 399
Query 1012 VNRYNEIQIQLIRQVAQQVLESFIHIDTQSEECTQIDVMEIRHQL 1056
N Y+ I+ + + V E +TQ+ + E +H++
Sbjct 400 ENVYDTTIIETLEKHIITVAEQVAEDETQTLRDINLVSKEEQHRI 444
Score = 59.3 bits (142), Expect = 7e-11
Identities = 92/443 (21%), Positives = 176/443 (40%), Gaps = 36/443 (8%)
Query 24 GLSERISTEAVEHYTENQIINIEKNGVQLSFTEERAWMLHQQDPLASSGPFILAFRLSGE 83
GL E I + Y+ Q + EK +LS ++R ++L Q + S ++ G
Sbjct 1027 GLGEYIRSTKDSVYSSIQKVE-EKEYYRLSSAQKRLYILDQIEGSGLSYNIPFTMKVKGR 1085
Query 84 IEISRLSNAIQKLYEGDSNLNLRYDLDDEGILNKYHDEHTPFEMNIHVVKSEQEAVQYLL 143
+I R NA++ + + L + + D + K E + +I K + ++Q ++
Sbjct 1086 FDIRRFENALKTIIQRHEALRTSFLMADGEPVQKIEKE---VDFSIKCSKIQSLSIQEII 1142
Query 144 SWIQKPINLAKAPAIQFTLLPQSHHEVILGILGHHILLDDSAWQPIFAQLSQNYA--QLD 201
+P +L KAP + ++ E I+ HHI+ D ++ + ++ Y +L
Sbjct 1143 KQFVRPFDLKKAPLFRTEVVKVDDEEHIILFDMHHIISDGASMGVLTKEICDLYGGKELK 1202
Query 202 GVLTASNSHIELSSKIPAKVLVNSQNALQYWKTIFPTGLNQLDWPKFCRAPNVQASIIQY 261
+ + E K + Q +YW IF + L+ P P + +
Sbjct 1203 PLSLQYKDYSEWQRDFYQKDEMKRQK--EYWLNIFKGEIPVLNMPTDYPRPQMHS---VE 1257
Query 262 GQNTIFDYEQKAVRCSSSIPLKGLKQLSERAQASIFHTVVAQFGGYLNHLFGTQSIDLFV 321
G F + + K LK++++ A+++ ++A + L G + + +
Sbjct 1258 GDRIGFAIDGELT--------KKLKRIAKDNGATMYMLLLAAYTVLLRTYSGQEDVIIGT 1309
Query 322 PIVEQYEASSLSQIRSSSNILPIRILRPEYSEQESNIENKEKESIVNVRNQILQ--GMVH 379
PI + I N L +R +++ ++ ++ NQ Q +V
Sbjct 1310 PIQGRKHHELKHVIGMFVNTLAMRNHPKGDKTFAEYLQDVKETALKAYENQDYQFDDLVE 1369
Query 380 NISIEQILSATKTKRNTIPNVLVTQFIDGSQFLKLEQVETSTLIIPPIHSD-----YDLT 434
+ +E+ +S RN + T F+ Q L+ E L P SD +DLT
Sbjct 1370 QLDLERDMS-----RNPL---FDTMFV--LQNLEKADAEIEGLTFEPFESDIHISKFDLT 1419
Query 435 LAFQIKADEIHFELTTGEKLSKK 457
L+ K +I F+L KL K+
Sbjct 1420 LSAIEKDSKIEFDLEYCTKLFKR 1442
Score = 58.2 bits (139), Expect = 1e-10
Identities = 86/397 (22%), Positives = 173/397 (44%), Gaps = 41/397 (10%)
Query 409 SQFLKLEQVETSTLII--PPIHSDYDLTLAFQIKADEIHFELTTGEKLSKKIGLLLLEQW 466
+Q LKL++++ + +I HSDY L I + E E L K++ ++ +
Sbjct 1902 NQLLKLDKIDEAAVIARKDDDHSDY---LCAYIVSKEDWTSTEISEWLEKELPHYMIPAY 1958
Query 467 IEFLHLDAQQRLEEAAIFAFGHQASPYGSDQEHWAQPTSSVQPQVDASITQLILDEFKQV 526
F+ LD +L + +A P + H A P+ D ++D ++ V
Sbjct 1959 --FVRLD---KLPLTSNDKVDRKALP--APDRHVATGAVYEAPRNDTEAK--LVDIWRDV 2009
Query 527 LMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTALELSQCVEYLSD 586
L ++ +FF GG SI A +++ +L ++ GL +++ D F P +L++ V+ S
Sbjct 2010 LGAGDIGISHHFFAAGGDSIKALQIVSRL-SRLGLKLEMKDLFANPRIKDLAKYVKKQSQ 2068
Query 587 RVKDSSVADDNREIVAPLTLLQKAFMGFSNQGRDAMYNIPFAFRFSETVNEQAFYDAFLD 646
R +++ + E LT +QK + + + D +N F +E AF
Sbjct 2069 RKNANTIVTGHAE----LTPIQKWYFANNKEELD-HFNQSFVLFRKGGFDESCVKKAFNK 2123
Query 647 ILKRHHVMRSIFVQADQGEIFQTVIPMDRLNQHPWFWGSEHQV---GQSAQQI--LRAEA 701
I+++H +R I+ ++G F I +R + F + V + A+++ L
Sbjct 2124 IMEQHDALRMIY--EEKGGDF---IQYNRSFREDLFDLDVYDVRGLDRQAEKVYELATSI 2178
Query 702 NHSFDLMQEFPIRVRFMKDEQGQHILSMLLYHIAMDEWSSGILMRELIQAYTSRVDG--- 758
+ + + + + ++G H+L ++++H+ +D S IL + Y+ + G
Sbjct 2179 QKLSSIRKGKLVHLGIFRADEGDHLL-IVIHHLVVDGVSWRILFEDFETLYSQALKGQTL 2237
Query 759 ----KAPIWEKTPRQFHEYAMAQDDSALQAHIQYWMN 791
K +++ R+ YA ++ L +YW N
Sbjct 2238 EIGYKTDSYQEFARRLKAYAHSR---TLSKEAEYWRN 2271
Score = 57.4 bits (137), Expect = 3e-10
Identities = 97/463 (21%), Positives = 187/463 (40%), Gaps = 53/463 (11%)
Query 12 LLSLFESK-LQDIGLSERISTEAVEHYTENQIINI----EKNGVQLSFTEERAWMLHQQD 66
L LFE+ ++DIG + +E E+ +I EK LS + R ++L+Q +
Sbjct 3552 LRQLFETPTIKDIG-------DFIESMKESPYASITQAEEKEYYALSSAQRRLYILNQIE 3604
Query 67 PLASSGPFILAFRLSGEIEISRLSNAIQKLYEGDSNLNLRYDLDDEGILNKYHDEHTPFE 126
P S A +++G+ ++ R +A ++L E L + + D + K E +
Sbjct 3605 PGGLSYNMPFAMKIAGDFDVDRFEDAFRQLIERHEALRTAFVMVDGEPVQKIEKE---VD 3661
Query 127 MNIHVVKSEQEAVQYLLSWIQKPINLAKAPAIQFTLLPQSHHEVILGILGHHILLDDSAW 186
+ + Q+ ++ + KP L KAP ++ +L S E +L + HHI+ D +
Sbjct 3662 FKVKYGRLGQDPLEEKIKAFIKPFALEKAPLLRAEVLKASGDEHVLMLDMHHIISDGVSM 3721
Query 187 QPIFAQLSQNY--AQLDGVLTASNSHIELSSKIPAKVLVNSQNALQYWKTIFPTGLNQLD 244
+L++ Y L + E K V Q YW +F + L+
Sbjct 3722 AIFTRELAELYEGKTLPPLTIQYKDFSEWQKLFYQKDEVKRQE--DYWLNVFQGEVPVLN 3779
Query 245 WPKFCRAP---NVQASIIQYGQNTIFDYEQKAVRCSSSIPLKGLKQLSERAQASIFHTVV 301
P + P +++ I+Q+ D E A+ L +L++ A+++ ++
Sbjct 3780 LPADEKRPQKRSIEGDIVQFE----IDGETSAM----------LNKLAKENGATMYMLLL 3825
Query 302 AQFGGYLNHLFGTQSIDLFVPIVEQYEASSLSQIRSSSNILPIRILRPEYSEQESNIENK 361
A + L G + I + PI ++ + I N L +R P+ ++ +
Sbjct 3826 AGYTTLLAKYTGQEDIVVGSPIAGRHHSDLKHVIGLFINTLAMR-NHPKGDMPFADYLKE 3884
Query 362 EKESIVNV---RNQILQGMVHNISIEQILSATKTKRNTIPNVLVTQFIDGSQF----LKL 414
KE+ + ++ +V + +++ +S + +LV Q DG + L
Sbjct 3885 VKETALKAYENQDYPFDELVEKLDVKRDMS----RHPLFDTMLVLQNFDGDEADIDGLTF 3940
Query 415 EQVETSTLIIPPIHSDYDLTLAFQIKADEIHFELTTGEKLSKK 457
+ ++T I S +DLTL + I KL K+
Sbjct 3941 QPLQTEVNI-----SKFDLTLTAAETNEGIQCVFNYSTKLFKR 3978
Score = 38.9 bits (89), Expect = 1e-04
Identities = 18/68 (26%), Positives = 34/68 (50%), Gaps = 0/68 (0%)
Query 523 FKQVLMNPNLQADDNFFDFGGHSILATRVIGKLQTQHGLLIKIADFFNAPTALELSQCVE 582
++ +L + + N FD G +S+ + +L + G + D F+ PT ELS ++
Sbjct 6060 WEDILNIEQIGINANIFDIGANSLNVMSFVSRLYAELGFRVPFKDIFSKPTIKELSDFLK 6119
Query 583 YLSDRVKD 590
+ D +KD
Sbjct 6120 HAQDLLKD 6127
Score = 38.1 bits (87), Expect = 2e-04
Identities = 20/79 (25%), Positives = 46/79 (58%), Gaps = 4/79 (5%)
Query 125 FEMNIHVVKSEQEAVQ---YLLSWIQKPINLAKAPAIQFTLLPQSHHEVILGILGHHILL 181
F++ ++ V SE + Q L + +Q+ I++ P ++ + ++ + +L I+ HH+++
Sbjct 4700 FDLFVYDVSSENDQPQKVYQLATELQQSIDIETGPLVKLAVFKTNNGDHLLIII-HHLVV 4758
Query 182 DDSAWQPIFAQLSQNYAQL 200
D +W+ +F L+ Y+QL
Sbjct 4759 DGISWRILFEDLAIGYSQL 4777
Score = 33.5 bits (75), Expect = 0.005
Identities = 51/260 (20%), Positives = 107/260 (41%), Gaps = 23/260 (9%)
Query 147 QKPINLAKAPAIQFTLLPQSHHEVILGILGHHILLDDSAWQPIFAQLSQNYA-QLDGVLT 205
+K +L+K ++ LL + L HHILLD I +L Y +++G +
Sbjct 2648 KKGFDLSKDVLMRAYLLKTAERSYRLVWSHHHILLDGWCLGIIMRELFVIYENRMNGKAS 2707
Query 206 ASNSHIELSSKIPAKVLVNSQNALQYWKTIFPTGLNQLDWPKFCRAPNVQASIIQYGQNT 265
S I + + A QYW+ Q P ++ + +++
Sbjct 2708 PLKETKPYSDYIKWLERQDQEEARQYWREYLKGYEEQAQLP----------TLTKRKKSS 2757
Query 266 IFDYEQKAVRCSSSIPLKGLKQLSERAQASIFHTVVAQFGGYLNHLFGTQSIDLFVPIVE 325
+D +K + S + K LK+L+ + ++ HTV+ G + + +F +V
Sbjct 2758 RYDRREKVIHLSKQL-TKQLKELAAKNSVTL-HTVIQTIWGLMLTRYTKIDDVVFGTVVS 2815
Query 326 QYEAS---SLSQIRSSSNILPIRILRPEYSEQESNIENKEKESIVNVRNQILQGMVHNIS 382
EA+ I N +P RI E + ++ ++++I + R + ++
Sbjct 2816 GREANVDGIEDMIGLFINTIPTRIRFNEQARFNDCLQKVQEDAIQSNR-------YNYMN 2868
Query 383 IEQILSATKTKRNTIPNVLV 402
+ ++ + + K++ I ++LV
Sbjct 2869 LAEVQALSSLKKDLIDHILV 2888
Score = 33.1 bits (74), Expect = 0.006
Identities = 86/412 (21%), Positives = 159/412 (39%), Gaps = 61/412 (15%)
Query 57 ERAWMLHQQDPLASSGPFI-LAFRLSGEIEISRLSNAIQKLYEGDSNL--NLRYDLDDE- 112
+R + H + S F +A + G I+ + + E L ++ Y++ DE
Sbjct 5098 QRGMLFHALEDKESQAYFEQMAINMKGLIDERLFAETFNDIMERHEILRASIEYEITDEP 5157
Query 113 -GILNK-------YHD--EHTPFEMNIHVVKSEQEAVQYLLSWIQKPINLAKAPAIQFTL 162
++ K YHD + +P E EQ Y + +K L P I+ L
Sbjct 5158 RNVIIKDRKINLDYHDLRKQSPAER-------EQVIQAYRKADREKGFRLNSEPLIRAAL 5210
Query 163 LPQSHHEVILGILGHHILLDDSAWQPIFAQLSQNYAQLDGVLTASNSHIELSSKIPAKVL 222
+ HHILLD + I +L Y + A H L P
Sbjct 5211 MRTEDDSYTFIWTNHHILLDGWSRGIIMGELFHMYHMKE----ARQKH-RLEEARPYSDY 5265
Query 223 V------NSQNALQYWKTIFPTGLNQLDWPKFCRAPNVQASIIQYGQNTIFDYEQKAVRC 276
+ + + A YW+ + +G + ++P S++ G + Y++K
Sbjct 5266 IGWLQQQDKEAAKAYWRN-YLSGFTE-------KSP---ISVLA-GSSGHAKYKRKEAVI 5313
Query 277 SSSIPLKG-LKQLSERAQASIFHTVVAQFGGYLNHLFGTQSIDLFVPIVEQYEASSL--- 332
L G + +L+ R + FHTV+ G L + +F ++ +A
Sbjct 5314 EFPEQLTGRITELASRNNVT-FHTVLQCIWGMLLARYNQTDDVVFGTVISGRDAQVTGIE 5372
Query 333 SQIRSSSNILPIRILRPEYSEQESNIENKEKESIVNVRNQILQGMV-HNISIEQILSATK 391
+ N +P RI R + S+ KE I +V+ Q L+G H++++ ++ S ++
Sbjct 5373 KMVGLFINTVPTRI-RLDKSQ-------SFKELIKSVQEQALEGRTYHDMNLSEVQSLSE 5424
Query 392 TKRNTIPNVLVTQ--FIDGSQFLKLEQVETSTLIIPPIHSDYDLTLAFQIKA 441
KR + ++L+ + +D S F + + + IH++ F I A
Sbjct 5425 LKRELLDHILIFENYAVDQSAF-ETSGKRGAGFVFEEIHAEEQTNYGFNIVA 5475
Score = 32.7 bits (73), Expect = 0.008
Identities = 34/165 (21%), Positives = 75/165 (45%), Gaps = 13/165 (8%)
Query 82 GEIEISRLSNAIQKLYEGDSNLNLRYDLDDEGILNKYHDEHTP--FEMNIHVVKS---EQ 136
G + S + A K+ E L + Y+ + G +Y+ F+++++ V+ +
Sbjct 2110 GGFDESCVKKAFNKIMEQHDALRMIYE-EKGGDFIQYNRSFREDLFDLDVYDVRGLDRQA 2168
Query 137 EAVQYLLSWIQKPINLAKAPAIQFTLLPQSHHEVILGILGHHILLDDSAWQPIFAQLSQN 196
E V L + IQK ++ K + + + +L ++ HH+++D +W+ +F
Sbjct 2169 EKVYELATSIQKLSSIRKGKLVHLGIFRADEGDHLLIVI-HHLVVDGVSWRILFEDFETL 2227
Query 197 YAQ-LDG----VLTASNSHIELSSKIPAKVLVNS-QNALQYWKTI 235
Y+Q L G + ++S+ E + ++ A + +YW+ I
Sbjct 2228 YSQALKGQTLEIGYKTDSYQEFARRLKAYAHSRTLSKEAEYWRNI 2272
Lambda K H a alpha
0.320 0.134 0.389 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 58822341
Database: ead2a0000399eb037f7fb832f9bf13b4.SwissProt.fasta
Posted date: May 19, 2024 9:05 PM
Number of letters in database: 60,051
Number of sequences in database: 11
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
