BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 250d27764c932d43552d88b924e9ed70.SwissProt.fasta
10 sequences; 32,416 total letters
Query= ACIAD2784
Length=2001
Score E
Sequences producing significant alignments: (Bits) Value
Q7CGD9 Toxin CdiA [Yersinia pestis] 294 3e-82
I1WVY3 tRNA nuclease CdiA-2 [Burkholderia pseudomallei (strain 10... 280 5e-78
D5CBA0 16S rRNA endonuclease CdiA [Enterobacter cloacae subsp. cl... 254 3e-70
A0A1S4NYE3 tRNA nuclease CdiA [Escherichia coli (strain STEC_O31)] 236 1e-64
Q3YL96 Toxin CdiA [Escherichia coli] 235 2e-64
B3BM48 tRNA nuclease CdiA [Escherichia coli O157:H7 (strain EC869)] 232 2e-63
Q0T963 tRNA nuclease CdiA [Escherichia coli O6:K15:H31 (strain 53... 232 2e-63
P0DSI1 tRNA nuclease CdiA [Escherichia coli (strain NC101)] 221 5e-60
P12255 Filamentous hemagglutinin [Bordetella pertussis (strain To... 197 1e-52
C4SGN7 tRNA nuclease CdiA [Yersinia mollaretii (strain ATCC 43969... 196 2e-52
>Q7CGD9 Toxin CdiA [Yersinia pestis]
Length=3295
Score = 294 bits (752), Expect = 3e-82
Identities = 281/888 (32%), Positives = 416/888 (47%), Gaps = 108/888 (12%)
Query 1 MNKNRYRVVYNQARQMFMAVAENVKSQTKTSGQSTASSVTVEQSQPFHQLWQVKCLVASM 60
MNKN YR+V+NQAR M M VA+ S S S+ T + + L+A
Sbjct 1 MNKNLYRIVFNQARGMLMVVADIAASGRAASSPSSGVGHTQRRRVSALSPLSFRLLIALG 60
Query 61 SLWMPLAPVYAQIQADNSANAGNRPVIGVGQNSQGQNVPVVNIQTPTNG-VSHNIYKQMD 119
+ + A I AD SA +P I S P VNIQTP++G VS N Y+Q D
Sbjct 61 CISLS---AQAAIVADGSAPGNQQPTI----ISSANGTPQVNIQTPSSGGVSRNAYRQFD 113
Query 120 VLPEGVVLNNSRTGANSSLVGTVGANPFLAKGEARIILNEVNSSVASRFEGNLEVAGQRA 179
V GV+LNN R + + G V NP+LA+GEA +ILNEVNS S+ G +EVAG++A
Sbjct 114 VDNRGVILNNGRGVNQTQIAGLVDGNPWLARGEASVILNEVNSRDPSQLNGYIEVAGRKA 173
Query 180 DVIIANPAGINIKGGGFINANKAILTTGKPQLNADGSIQQFVVDQGKITISANSGSSLGL 239
V+IANPAGI +G GFINAN+A LTTG+ QLN +G + + V++G+I I G
Sbjct 174 QVVIANPAGITCEGCGFINANRATLTTGQAQLN-NGQLTGYDVERGEIVIQ-------GK 225
Query 240 GGNKNNADYVDLYARALELNAQLYANKDIQAITGANNISADLQQISTRTGTGT-TPTLAI 298
G + D+ DL AR++++NA ++AN ++ TG N + A Q I+T G P +A+
Sbjct 226 GLDSRGQDHTDLIARSVKVNAGIWAN-ELNITTGRNQVDAAHQNINTNAADGRHRPAVAV 284
Query 299 DVKNLGGMYANNIYLLGNEKGLGVSNAGTIRA-VNNLVVTSAGKIEHKGSLEST------ 351
DV NLGGMYA I L+G E G+GV NAG I A ++V+T+ G + ++G + S
Sbjct 285 DVANLGGMYAGKIRLIGTETGVGVHNAGEIGASAGDIVITADGMLVNRGQISSAQQLAVN 344
Query 352 -----SNTQGLVSIQTTQTGDNGNINSSGSITSKSMLSIDAANHLNITGNQVIVNQGVVS 406
N+ L TQ G +++SG++ + I AA +N + N V+ G+ S
Sbjct 345 TPSGIENSGVLYGKGNTQLTTAGKLSNSGTVAAAGDTLIRAA-EVNSSRNSVL-GAGIKS 402
Query 407 PLLLSAQGDINVSNGAIIKNVQTGGDIYLDAQNINVG----ENTQIANVGLVNLNAAAAI 462
+G +++ A + G +I AQ N +Q + L I
Sbjct 403 DNSAITRGTLDIK--ARGQLTAQGKNISGTAQTFNANRIDLSGSQTQSGDLTFTTEGGDI 460
Query 463 DIKKSARVKAVNDLNIIAKQGLSVADANLVAEKGNMNLQSNSNITLQGTTLDLTKDLNIN 522
D+ A + A L++ L ANL AE+ ++ Q+ +N+ T LT D N+N
Sbjct 461 DL-TGANLFANRRLSVSTPSLLRTDKANLFAEQIALDAQALANVGGVITQTGLT-DFNLN 518
Query 523 GTGNVN------LSSLNFSLLNGSSTLQNINAYSGLNLVWDQTAKALPQISGNVTLEAAN 576
G+++ L+ NF LL N + G + D K P+ NVT A
Sbjct 519 LPGDIDNRDGTLLTRGNF-LLQAEHLTSNSQSLLGAGIQSD--GKLAPRGDLNVTTRHA- 574
Query 577 LIDLKGSNLSGKGDLKLQGKALNVGADLTAGKSLNLTATQSDLILNKTLNAQGNIDIASL 636
+ +G L+ G L L G L++ LT K + LTAT+ D+ L N A
Sbjct 575 -LIAQGKTLTA-GTLALSGSRLDLTDSLTQAKYMRLTATEGDIALTGATVMAANTLFADT 632
Query 637 DGKLNATGLNATSSQGKLSIFGAKD----TVLTNSGTVKTTLKGNQGVNVGTIST-GNLT 691
L + T+ Q L+ + + V SG + L G G + T GNL
Sbjct 633 RQILRSDKAYLTADQINLTAYSLSNVEGRVVQKGSGDFRLDLPGYLDNRGGVLLTKGNLA 692
Query 692 LQNTVLESQNGAIV---VTSEG--------QNTLTDSIITAKGNIELFAKDNLTLDGIK- 739
LQ L S + +++ + ++G Q T ++I N+ A +TL G +
Sbjct 693 LQAERLTSNSQSLLGAGIQADGSKASKGDLQANTTQALIAQGQNV---AAGTMTLSGSRV 749
Query 740 --SSSQQHTALNSKKNIYINSQAGTGDSVNFSSTKITELNSTGTLSL--ISDKNQNLQNT 795
+ SQ H + NI I A GD +T IT GTLS+ +++ Q L N
Sbjct 750 DLTGSQTHAS-----NITIT--ARDGDVTTREATLIT----PGTLSMTAVANPEQTLNN- 797
Query 796 RLTGGAILLEAGGTLNTPKVIEFNATGSNLLKNDSKLNSLNGDLSIQT 843
GG L+ N+ N +KL + NG+++ T
Sbjct 798 ----------RGGKLH----------ADNIQLNLAKLENSNGEIAAAT 825
Score = 73.2 bits (178), Expect = 5e-15
Identities = 205/964 (21%), Positives = 372/964 (39%), Gaps = 163/964 (17%)
Query 73 IQADNSANAGNRPVIGVGQNSQGQNVPVVNIQTPTNGVSHNIYKQMDVLPEGVV-LNNSR 131
+QA++ + ++ ++G G S G+ P ++ T H + Q L G + L+ SR
Sbjct 538 LQAEH-LTSNSQSLLGAGIQSDGKLAPRGDLNVTTR---HALIAQGKTLTAGTLALSGSR 593
Query 132 TGANSSLVGTVGANPFLAKGEARIILNEVNSSVASRFEGNLEVAGQRADVIIANPAGINI 191
SL + + EG++ + G A V+ AN +
Sbjct 594 LDLTDSLT-------------------QAKYMRLTATEGDIALTG--ATVMAANTLFADT 632
Query 192 KGGGFINANKAILTTGKPQLNADG--SIQQFVVDQGKITISANSGSSL-GLGGNKNNADY 248
+ + ++KA LT + L A +++ VV +G + L GG
Sbjct 633 RQ--ILRSDKAYLTADQINLTAYSLSNVEGRVVQKGSGDFRLDLPGYLDNRGGVLLTKGN 690
Query 249 VDLYARALELNAQLYANKDIQAITGANNISADLQQISTRTGTGTTPTLAIDVKNLGGMYA 308
+ L A L N+Q IQA G+ DLQ TT L +N+ A
Sbjct 691 LALQAERLTSNSQSLLGAGIQA-DGSKASKGDLQ-------ANTTQALIAQGQNVA---A 739
Query 309 NNIYLLGNEKGLGVSNAGTIRAVNNLVVTSA-GKIEHKGSLESTSNTQGLVSIQTTQTGD 367
+ L G+ L G+ +N+ +T+ G + + E+T T G +S+ T
Sbjct 740 GTMTLSGSRVDL----TGSQTHASNITITARDGDVTTR---EATLITPGTLSM-TAVANP 791
Query 368 NGNINSSGSITSKSMLSIDAANHLNITGNQVIVNQGVVSPLLLSAQGDINVSNGAIIKNV 427
+N+ G + ++ A N G + L L Q D GA +
Sbjct 792 EQTLNNRGGKLHADNIQLNLAKLENSNGEIA-----AATDLWLRLQSDFIHQAGA---RL 843
Query 428 QTGGDIYLDAQN-------INVGENTQIANVGLVNLNAAAAIDIKKSARVKAVNDLNIIA 480
G D+ +++ + G + Q+ + + N +A + S+ ++A
Sbjct 844 TAGRDLLFNSRGALINQYKLEAGRDMQLTALSIRNTSADRNTNADNSS---------LLA 894
Query 481 KQGLSVADANLVAEKGNMNLQSNSNITLQGTTLDLTK---DLNINGTGNVNLSSLNFSLL 537
+GLS++ +L +G + T+ G T ++ + + + T NL++
Sbjct 895 GRGLSLSTDSLF-NRGAIYTTGVGQFTVNGNTENIGEIYTEQQLTFTATGNLANRGVMQT 953
Query 538 NGSSTLQNINAYSGLNLVWDQTAKALPQISGNVT----LEAAN---------LIDLKGSN 584
G L + +++ + I+GN+T L AN +D +GS
Sbjct 954 RGEMQLSAQGDVNNSGMLYSAGDQMRLSIAGNLTNEGKLHVANGEMRLLTEGNLDNRGSL 1013
Query 585 L-SGKGDLKLQGKALNVGADLTAGKSLNLTATQSDLILNKTLNAQGNI-----DIASLDG 638
+G D+ QG A+N G+ T G L T+ + + ++ A G++ D+ S +
Sbjct 1014 YGAGNSDITTQGNAVNTGSVYTQGALQWL--TKGSVRNSASIAALGDLQLRANDLLSDNQ 1071
Query 639 KLNATGLNATSSQ---GKLSIFGAKDTVLTNSGTVKTTLKGNQGVNVGTISTGNLTLQNT 695
L A GL A S+ G L++ T + + Q + G+++ + T
Sbjct 1072 SLMAAGLKADGSRSDSGNLAV-----------STEQALIAQGQNIAAGSLALAGSQIDLT 1120
Query 696 VLESQNGAIVVTSE-GQNTLTDSIITAKGNIELFAKDNLTLDGIKSSSQQHTALNSKKNI 754
++Q AI +T++ G TLT ++I A + + T L + ++
Sbjct 1121 GSQTQANAISLTAKSGDITLTSAVIKAATQLLV------------------TQLAATRSS 1162
Query 755 YINSQAGTGDSVNFSSTKITELNS----TGTLSLISDKNQNLQNTRLTGGAILLEAGGT- 809
+I + S SST+ + S T SLI+D+ G ++ + G T
Sbjct 1163 FIPPSSIPPSSTQSSSTQASASPSAWLRTDKASLIADQLTFDVQALSNLGGVIAQTGATD 1222
Query 810 --LNTPKVIEFNATGSNLLKNDSKLNS--LNGDLSIQTKESLTIDPNIHTLKAIGDIELA 865
LN P ++ N G+ L K + + + L+ D + D L GD+ +
Sbjct 1223 FNLNLPGYLD-NRGGTILSKGNVAIQAQGLDSDSGSLLGAGVQSDGK---LTNAGDLAVT 1278
Query 866 SKQGTLILAGYGGQAGNGSEKVLNLTTTGGGISLEGASVELQGAQLNAEK--------NI 917
+Q LI G AG +T TG G+ L G+ + +G + A K NI
Sbjct 1279 VRQ-DLIAHGQSLAAG-------AMTLTGSGVDLTGSQTQARGITITANKGDVSTQRANI 1330
Query 918 KILANNENIQIISIKNKLNNSKLS-DSNKLLVDLVEIDNKLKKISINNQYTELFLADVKI 976
L + + LNN S +N + ++L ++DN+ KI+ + +D I
Sbjct 1331 LSLGSLAINAGANAGQTLNNQGGSLQANNIALNLGQLDNRTGKIAASQDLVLGLQSDFNI 1390
Query 977 LENA 980
L ++
Sbjct 1391 LADS 1394
Score = 63.5 bits (153), Expect = 4e-12
Identities = 179/839 (21%), Positives = 337/839 (40%), Gaps = 134/839 (16%)
Query 31 SGQSTASSVTVEQSQPFHQLWQVKCLVASMSLWMPLAPVYAQIQADNSANAGNRPVIGVG 90
+G++ AS EQ+Q F QL+ S LAP ++ A+ A V+
Sbjct 1897 TGRTVASDYRSEQAQ-FEQLFAAG---VQYSKAFNLAPG-TRLSAEQMATLTGNIVLMEN 1951
Query 91 QNSQGQNV--PVVNIQTPTNGVSHNIYKQMDVL--PEGVVLNNSRTGANSSLVGTVGANP 146
++ GQ V PVV + GV + L E + L + AN+ G + A+
Sbjct 1952 RDVAGQTVLVPVVYLA----GVKPGDLRANGALIAAENISLTEVQGFANA---GAISASN 2004
Query 147 FLAKGEARIILNEVNSSVASRFEGN-LEVAGQRADVIIANPAGINIKGGGFINANKAILT 205
L A+ I +N+ GN L+++ +D+ + + A +N + IL
Sbjct 2005 NLQISMAKDIT--LNNRCGLLQAGNHLQLSTLNSDIDLTS-ARLNATNLQLDSGRDVILR 2061
Query 206 TGKPQLNA-DGSIQQFVVDQGKITISANSGSSLGLGGNKNNADYVDLYARALELNAQLYA 264
T Q ++ +G++Q+ G + +SL + N D + +N
Sbjct 2062 TASDQYSSGNGAVQRTQTILGPL-------ASLNISNNAVITAQRDFIQQGAGINI---- 2110
Query 265 NKDIQAITGANNISADLQ---QISTRTGTGTTPT-----LAIDVKNLGGMYANNIYLLGN 316
KD+Q TG + + + +Q QIS + G G+ + L +VK G + AN + N
Sbjct 2111 GKDLQVNTGGDWLLSTVQRSDQISAQYGGGSATSGSLRHLGSEVKVGGALSAN----VDN 2166
Query 317 EKGLGVS-NAGTI--RAVNNLVVTSAGKIEHKGSLESTSNTQGLVSIQTTQTGDNGNINS 373
+G NAGTI RA N + + + G S +T + T G +N+
Sbjct 2167 LTAVGARVNAGTIDVRAQNITLSAATDSLSVTGGSSSKRHTSSVNLYDETLLGSQ--LNA 2224
Query 374 SGSITSKSMLSIDAANHLNITGNQVIVNQGVVSPLLLSAQGDINVSNGAIIKNVQ---TG 430
+G I ++ N + ++ + V + L L+A GD+ +++ + Q TG
Sbjct 2225 TGDI------NLQTVNDITLSASAVQTD----GALKLAAGGDVTLTSQTEQHDEQRNHTG 2274
Query 431 GDIYLDAQNINVGENTQIANVGLVNLNAAAAIDIKKSARVKAVNDLNIIAKQGLSVADAN 490
L + E + + + ++ +A +ID+ + Q ++VA ++
Sbjct 2275 TKKGLLSSTTTRSEEGRSQTLAVGSMLSAGSIDV---------------SSQNIAVAGSS 2319
Query 491 LVAEKGNMNLQSNSNITLQ-------GTTLDLTKDLNINGTGNVN--LSSLNFSLLNGSS 541
+VA+K ++ L++ N+T+ G+ L K + TG + + + + +
Sbjct 2320 VVADK-DIRLRAQENLTVSTAQQSESGSQLFEQKKSGLMSTGGIGVFIGTSRQKTTDQTQ 2378
Query 542 TLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANLIDLKGSNLSGKGDLKLQGKALNVG 601
T+ ++ + G ++GNV LEA N + L GS++ DL L G + +
Sbjct 2379 TVSHVGSTVG-------------SLTGNVRLEAGNQLTLHGSDVVAGKDLALTGADVAIS 2425
Query 602 A-------DLTA-GKSLNLT---------ATQSDLILNKTLNAQGNIDIASLDG-KLNAT 643
A TA K LT A + + K + +A L G K +
Sbjct 2426 AAENSRSQQYTAESKQRGLTVALSGPVGSAVNTAVTTAKAAREENTGRLAGLQGVKAALS 2485
Query 644 GLNATSSQGKLSIFGAKDT----VLTNSGTVKTTLKGNQ---GVNVGTISTGNLTLQNTV 696
G+ A + + G T V + G+ K++ + Q V+ ++ GN N
Sbjct 2486 GVQAVQAGQLVQAQGGGITEMVGVSVSLGSQKSSSQQQQEQTQVSGSALTAGN----NLS 2541
Query 697 LESQNGAIVVTSEGQNTLTDSIITAKGNIELF-AKDNLTLDGIKSSSQQHTALN---SKK 752
+++ I++ D+ + A +++L A + DG SS ++ S
Sbjct 2542 IKASGSDILIAGSQLKAGGDTRLDAARDVQLLGAANRQKTDGSNSSRGGSVGVSVGGSGL 2601
Query 753 NIYINSQAGTGDSVNFSS-TKITELNSTGTLSLISDKNQNLQNTRLTGGAILLEAGGTL 810
+++ N+ G G+ + T ++S G SL S ++ L +++ + + G L
Sbjct 2602 SVFANANKGQGNERGDGTFWTETTVDSGGMFSLRSGRDTALTGAQVSAETVKADVGRNL 2660
Score = 48.1 bits (113), Expect = 2e-07
Identities = 158/733 (22%), Positives = 272/733 (37%), Gaps = 117/733 (16%)
Query 135 NSSLVGTVGANPFLAKGEARIILNEVNSSVASRFEGNLEVAGQRADVIIANPAGINIKGG 194
N+ V T GA +L KG R ++S+A+ + L +D AG+ G
Sbjct 1029 NTGSVYTQGALQWLTKGSVRN-----SASIAALGDLQLRANDLLSDNQSLMAAGLKADGS 1083
Query 195 GFINANKAILTTGKPQLNADGSIQQFVVDQGKITISANS----GSSLGLGGNKNNADYVD 250
+ N A+ T +Q ++ QG+ I+A S GS + L G++ A+ +
Sbjct 1084 RSDSGNLAVST------------EQALIAQGQ-NIAAGSLALAGSQIDLTGSQTQANAIS 1130
Query 251 LYARALEL---NAQLYANKDIQAITGANNISADLQQISTRTGTGTTPTLAIDVKNLGGMY 307
L A++ ++ +A + A + A S+ + S + + + +
Sbjct 1131 LTAKSGDITLTSAVIKAATQLLVTQLAATRSSFIPPSSIPPSSTQSSSTQASASPSAWLR 1190
Query 308 ANNIYLLGNEKGLGVSNAGTIRAVNNLVVTSAGKIEHKGSLESTSNTQGLVSIQTTQTGD 367
+ L+ ++ V +A++NL G I G+ + N G +
Sbjct 1191 TDKASLIADQLTFDV------QALSNL----GGVIAQTGATDFNLNLPGYLD-------- 1232
Query 368 NGNINSSGSITSKSMLSIDAANHLNITGNQVIVNQGVVSPLLLSAQGDINVS-NGAIIKN 426
N G+I SK ++I A + +G+ ++ GV S L+ GD+ V+ +I +
Sbjct 1233 ----NRGGTILSKGNVAIQAQGLDSDSGS--LLGAGVQSDGKLTNAGDLAVTVRQDLIAH 1286
Query 427 VQ---------TGGDIYLDAQNINVGENTQIANVGLVNLNAAAAIDIKKSARVKAVNDLN 477
Q TG + L T AN G V+ A + + A N
Sbjct 1287 GQSLAAGAMTLTGSGVDLTGSQTQARGITITANKGDVSTQRANILSLGSLAINAGANAGQ 1346
Query 478 IIAKQGLSVADANLVAEKGNMNLQSNSNITLQGTTLDLTKDLNINGTGNVNLSSLNFSLL 537
+ QG S+ N+ G ++ ++ Q L L D NI + + +FS
Sbjct 1347 TLNNQGGSLQANNIALNLGQLDNRTGKIAASQDLVLGLQSDFNILADSTLQ-AGRDFSFT 1405
Query 538 NGSSTLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANLIDLKGSN-LSGKGDLKLQGK 596
+ + +G L T +GN+ A DL+ S L+ +G++ +G
Sbjct 1406 THGALTNDGQLLAGRKL---STRSNSLLNNGNIRAVQA---DLRASGALTNRGEILTRG- 1458
Query 597 ALNVGADLTAGKSLNLTATQSDLILNKTLNAQGNIDIASLDGKLNATGLNATSSQGKLSI 656
L+ A+ + AT TLNA+ I + + + AT N T + +
Sbjct 1459 GLSTDANTLFNSGTLIGAT-------ATLNARERITNSGPNALIGATDKNGTLAL-LAPV 1510
Query 657 FGAKDTVLTNSGTVKTTLKGNQGV-------NVGTISTGNLTLQ-NTVLESQNGAIVVTS 708
DTV TTL G V N G S+ L + ++ES N +V
Sbjct 1511 IENSDTVTRTDTAPTTTLLGMGKVILAGGQDNSGNYSSAAQVLNLSGLIESGNDLLVYA- 1569
Query 709 EGQNTLTD--SIITAKGNIELFAKDNLTLDGIKSSSQQHTALNSKKN------IYINSQA 760
TLT+ I+TA T D I ++ A + +N Y A
Sbjct 1570 ---KTLTNRRQILTA------------TTDFIVGDTETGAAYWTAENPDIPGGRYTQPPA 1614
Query 761 GTGDSVNFSSTKITELNSTGTLSLISDKNQNLQNTRLTGGAILLEAGGTLNTPKVIE--- 817
G + ++ T T + + IS + Q L GG + L+ G N +
Sbjct 1615 GGPMNSDYIGTNYTSTVAYNRIDQISPEAQ-----LLAGGNLTLQVGTLENNWSKVSAQG 1669
Query 818 -FNATGSNLLKND 829
+ TG L ++D
Sbjct 1670 VIDLTGVTLQQDD 1682
Score = 45.4 bits (106), Expect = 1e-06
Identities = 275/1381 (20%), Positives = 487/1381 (35%), Gaps = 272/1381 (20%)
Query 124 GVVLNNSRTGANSSLVGTVG--ANPFLAKGEARIILNEVNSSVASRFEGNLEVAGQRADV 181
GV+ T N +L G + L+KG I ++S G+L AG ++D
Sbjct 1213 GVIAQTGATDFNLNLPGYLDNRGGTILSKGNVAIQAQGLDSD-----SGSLLGAGVQSDG 1267
Query 182 IIANPAGINIKGGGFINANKAILTTGKPQLNADGSIQQFVVDQGK-ITISANSGSSLGLG 240
+ N + + + A+ L G L G Q + ITI+AN G
Sbjct 1268 KLTNAGDLAVTVRQDLIAHGQSLAAGAMTLTGSGVDLTGSQTQARGITITANKGDV---- 1323
Query 241 GNKNNADYVDLYARALELNAQLYANKDIQAITG---ANNISADLQQISTRTGTGTTPTLA 297
+ A+ + L +L +NA A + + G ANNI+ +L Q+ RTG
Sbjct 1324 -STQRANILSL--GSLAINAGANAGQTLNNQGGSLQANNIALNLGQLDNRTGK------- 1373
Query 298 IDVKNLGGMYANNIYLLGNEKGLGVSNAGTIRAVNNLVVTSAGKIEHKGSL--------- 348
+ A+ +LG + + T++A + T+ G + + G L
Sbjct 1374 --------IAASQDLVLGLQSDFNILADSTLQAGRDFSFTTHGALTNDGQLLAGRKLSTR 1425
Query 349 -ESTSNTQGLVSIQTTQTGDNGNINSSGSITSKSMLSIDAANHLN----------ITGNQ 397
S N + ++Q +G + + G I ++ LS DA N + +
Sbjct 1426 SNSLLNNGNIRAVQADLRA-SGALTNRGEILTRGGLSTDANTLFNSGTLIGATATLNARE 1484
Query 398 VIVNQGVVSPLLLSAQGDINVSNGAIIKNVQTGGDIYLDAQNINVGENTQIANVGLVNLN 457
I N G P L D N + + ++ + + T + +G V L
Sbjct 1485 RITNSG---PNALIGATDKNGTLALLAPVIENSDTV----TRTDTAPTTTLLGMGKVILA 1537
Query 458 AAAAIDIKKSARVKAVNDLNIIAKQGLSVADANLVAEKGNMNLQSNSNITLQGTTLDLTK 517
S+ + +N +I E GN L +T + L T
Sbjct 1538 GGQDNSGNYSSAAQVLNLSGLI--------------ESGNDLLVYAKTLTNRRQILTATT 1583
Query 518 DLNINGT--GNVNLSSLNFSLLNGSSTLQNINA-----YSGLNLVWDQTAKALPQIS--- 567
D + T G ++ N + G T Y G N + QIS
Sbjct 1584 DFIVGDTETGAAYWTAENPDIPGGRYTQPPAGGPMNSDYIGTNYTSTVAYNRIDQISPEA 1643
Query 568 -----GNVTLEAANLIDLKGSNLSGKGDLKLQGKALNVGADLTAGKSLNLTATQSDLILN 622
GN+TL+ L + S +S +G + L G L D + + L T S
Sbjct 1644 QLLAGGNLTLQVGTL-ENNWSKVSAQGVIDLTGVTLQQD-DWGSQQRLVEQTTSSGEYRY 1701
Query 623 KTLNAQGNIDIASLDGKLNATGLNATSSQGKLSIFGAKDTVLTNSGTVKTTLKGNQGVNV 682
+T + + KL A+S K LT SGTV N G
Sbjct 1702 RTYKGKLWGIAWGPEMKLRLNNQYASSITAK---------TLTGSGTVINNTVINNGAAP 1752
Query 683 GTISTG---NLTLQNTVLESQNGAIVVTSEGQNTLTDSIITAKGNIELFAKDNLTLDGIK 739
G I + T +N +E A+ + G L T KG+ + L+L I
Sbjct 1753 GAIVAPRDRDSTGKNIAVEFNGIALTLPRSGLYQLK----TDKGDYAPGPEAALSLANIS 1808
Query 740 SSSQQHTALNSKKNIYINSQAGTGDSVNFSSTKITELNSTGTLSLISDKNQNLQNTRLTG 799
S L++TG + + +L T L
Sbjct 1809 PPSS--------------------------------LDATGPRG-VPPPSDDLNRTGLVT 1835
Query 800 GAILLEAGGTLNTPKVIEFNATGSNLLKNDSKLNSLNGDLSIQTKESLTIDPNIHTLKAI 859
+ G + T A+ +N +D L L+ D S+ K + N + + +
Sbjct 1836 PDRAVSGGYLVETHPAF---ASLNNWKGSDLYLQQLSSDPSVIHKR---LGDNAYEQRLL 1889
Query 860 GDIELASKQGTLILAGYGGQ---------AGNGSEKVLNL------------TTTGGGIS 898
D LA G + + Y + AG K NL T TG +
Sbjct 1890 RDQVLALT-GRTVASDYRSEQAQFEQLFAAGVQYSKAFNLAPGTRLSAEQMATLTGNIVL 1948
Query 899 LE-----GASVELQGAQLNAEKNIKILANN-----ENIQIISIKNKLNNSKLSDSNKLLV 948
+E G +V + L K + AN ENI + ++ N +S SN L +
Sbjct 1949 MENRDVAGQTVLVPVVYLAGVKPGDLRANGALIAAENISLTEVQGFANAGAISASNNLQI 2008
Query 949 DLVEIDNKLKKISINNQYTELFLAD---VKILENAYDI-AFNFNPSAYKEDASYRKGSDK 1004
+ K I++NN+ L + + L + D+ + N + + D+ G D
Sbjct 2009 SMA------KDITLNNRCGLLQAGNHLQLSTLNSDIDLTSARLNATNLQLDS----GRDV 2058
Query 1005 DIQFFNEVY---DGFVKKYSDIIEPNIYSQQLNGTKYSTQISIAVPFGDGDYARKEDILS 1061
++ ++ Y +G V++ I+ P + S ++ T + G G K+ ++
Sbjct 2059 ILRTASDQYSSGNGAVQRTQTILGP-LASLNISNNAVITAQRDFIQQGAGINIGKDLQVN 2117
Query 1062 PNGYFKYKYDQNKIRSEINYLSQLNGYEHFSSKLVSNSGSIDITSSKGISISGSELISKK 1121
G + Q + Y G +S + + GS ++ +S + L +
Sbjct 2118 TGGDWLLSTVQRSDQISAQY-----GGGSATSGSLRHLGS-EVKVGGALSANVDNLTAVG 2171
Query 1122 GLVNIEALGALSQNYTSTIHGKDNKPKTLGASIIIDGSQDFYDKGNENDQKYRFRTILKP 1181
VN + +QN T + D+ T G+S K + + T+L
Sbjct 2172 ARVNAGTIDVRAQNITLSA-ATDSLSVTGGSS----------SKRHTSSVNLYDETLL-- 2218
Query 1182 TLINGDKGVTIRATGNSNQ---DNLVLQATGITAANGDVRIEANKNILFDAAIEQSYDRS 1238
G + ATG+ N +++ L A+ + +G +++ A ++ + EQ ++
Sbjct 2219 -------GSQLNATGDINLQTVNDITLSASAVQT-DGALKLAAGGDVTLTSQTEQHDEQR 2270
Query 1239 TTTEKKSSWGGLKKKYIT--------TVSENNQANAASVDISGKNIFIESKEKNPANNID 1290
T K GL T T++ + +A S+D+S +NI +
Sbjct 2271 NHTGTKK---GLLSSTTTRSEEGRSQTLAVGSMLSAGSIDVSSQNIAV------------ 2315
Query 1291 IYSGKFIANGGQVSILSGGNINLYTVQESSSSNEDITKKSS----------FSGI-KYNT 1339
+G + + + + N+ + T Q+S S ++ +K S F G + T
Sbjct 2316 --AGSSVVADKDIRLRAQENLTVSTAQQSESGSQLFEQKKSGLMSTGGIGVFIGTSRQKT 2373
Query 1340 SKTNATRNQISELPGILKADYIGIKADNDVRLVGTEFEYLQAAKIQAGRNLSLLTASTTV 1399
+ T + + G L + + ++A N + L G++ + AG++L+L A +
Sbjct 2374 TDQTQTVSHVGSTVGSLTGN-VRLEAGNQLTLHGSD--------VVAGKDLALTGADVAI 2424
Query 1400 T 1400
+
Sbjct 2425 S 2425
Score = 38.1 bits (87), Expect = 2e-04
Identities = 128/630 (20%), Positives = 226/630 (36%), Gaps = 103/630 (16%)
Query 1169 NDQKYRFRTILKPTLINGDKGVTIRATGNSNQDNLVLQATGITAANGDVRIEANKNI-LF 1227
+ Q+ + +T + + + ++I+A+G+ +L A A GD R++A +++ L
Sbjct 2519 SSQQQQEQTQVSGSALTAGNNLSIKASGSD-----ILIAGSQLKAGGDTRLDAARDVQLL 2573
Query 1228 DAAIEQSYDRSTTTEKKS---SWGGLKKKYITTVSENNQANAASVDISGKNIFIESKEKN 1284
AA Q D S ++ S S GG + +S AN + G F +
Sbjct 2574 GAANRQKTDGSNSSRGGSVGVSVGG------SGLSVFANANKGQGNERGDGTFWTETTVD 2627
Query 1285 PANNIDIYSGKFIA-NGGQVSILS-----GGNINLYTVQESSSSNEDITKKSSFSGIKYN 1338
+ SG+ A G QVS + G N+ L + Q+ N D + + GI
Sbjct 2628 SGGMFSLRSGRDTALTGAQVSAETVKADVGRNLTLQSQQDRD--NYDAKQSRASGGISVP 2685
Query 1339 TSKTNATRNQISELPGILKADYIGIKADNDVRLVGTEFEYLQAAKIQAGRNLSL---LTA 1395
+ A N +S L + Y ++A + F I+ G + L + A
Sbjct 2686 VAGGGAAVN-LSMSRDRLSSQYDSVQAQTGI------FAGSGGVDIRVGEHTQLDGAVIA 2738
Query 1396 STTVTETLKKDKNSVVWQSMQDKGSVTETAQLPRFNGPTPPEFKAAGGLIVQIPIGEKDQ 1455
ST + D ++ + +++K T Q G L P+G
Sbjct 2739 STAAADKNTLDTGTLGFSDIKNKAVFTVEHQ--------------GGSLSTGGPVGSDLL 2784
Query 1456 NKIEIRDQILILANQPGNEYLK----QLVNRNDVDWQKVILAQKDWDYKSQGLTGAGAAI 1511
+ + ++LA Y + V+ + + Q++ D S+ A +I
Sbjct 2785 SNLGG----MVLAGLGNGGYAEGTTQAAVSEGTITVRDTENQQQNVDDLSRDTGNANGSI 2840
Query 1512 IAIIVVMVTAGAGSAV--VGALGGSATTLGGSAVVMTQAAVTSLATQASVSLINNGGDLG 1569
I V +G +GG A + +TQ + + D
Sbjct 2841 GPIFDKEKEQNRLKEVQLIGEIGGQALDIA--------------STQGKIIATHAANDKM 2886
Query 1570 KTLKD----LGSKDSVKNLAASVVTAGLLSQ--VGSALNLKPDTSGFSARLLNNFTTAVG 1623
K +K K K TA ++Q +A N + SGF
Sbjct 2887 KAVKPEDIAAAEKQWEKAHPGKAATAEDINQQIYQTAYNQAFNESGFGTGGPVQRGMQAA 2946
Query 1624 STLVQTAIKGGDLEDNLKVALLAGLAGAMQGELASQIGTHLDKVDPNVFEYAIHKIAHAA 1683
+ VQ + GG N+ AL A + G + G + A + +AHA
Sbjct 2947 TAAVQ-GLAGG----NMGAALTGASAPYLAGVIKQSTGDNP----------AANTMAHAV 2991
Query 1684 VGCAVAAATKSSCEAGAIGAGVGEIVASLMPDPVNGIEYN-----EDEKTKIRNTGKIVA 1738
+G A A+ ++ AGA GA E++A P ++ + ++ E +K + + A
Sbjct 2992 LGAVTAYASGNNALAGAAGAATAELMA---PTIISALGWDKNTLTEGQKQAVSALSTLAA 3048
Query 1739 GVVSAYAG---YDVNTAANSADIAIQNNSL 1765
G+ G D + A++NN L
Sbjct 3049 GLAGGLTGDSTADALAGGQAGKNAVENNLL 3078
Score = 30.8 bits (68), Expect = 0.032
Identities = 73/334 (22%), Positives = 125/334 (37%), Gaps = 59/334 (18%)
Query 582 GSNLSGKGDLKLQGKALNVG-ADLTAGKSLNLTATQSDLILN-KTLNAQG--NIDIASLD 637
G G G + L G A L G+ + ++++ K L+++G + D+ +
Sbjct 182 GITCEGCGFINANRATLTTGQAQLNNGQLTGYDVERGEIVIQGKGLDSRGQDHTDLIARS 241
Query 638 GKLNA----TGLNATSSQGKLSIFGAKDTVLTNSGTVKTTLKGNQGVNVGTISTGNLTLQ 693
K+NA LN T+ + ++ D N T + V V + G +
Sbjct 242 VKVNAGIWANELNITTGRNQV------DAAHQNINTNAADGRHRPAVAVDVANLGGMYAG 295
Query 694 NTVLESQNGAIVVTSEGQNTLTDSIITAKGNIELFAKDNLTLDGIKSSSQQHTALNSKKN 753
L + V + G+ I + G+I + A L G SS+QQ
Sbjct 296 KIRLIGTETGVGVHNAGE------IGASAGDIVITADGMLVNRGQISSAQQ--------- 340
Query 754 IYINSQAGTGDSVNFSSTKITELNSTGTLSLISDKNQNLQNTRLTGGAILLEAGGTLNTP 813
+ +N+ +G +S T+L + G LS + AG TL
Sbjct 341 LAVNTPSGIENSGVLYGKGNTQLTTAGKLS---------------NSGTVAAAGDTLI-- 383
Query 814 KVIEFNATGSNLLKNDSKLNS---LNGDLSIQTKESLTIDPNIHTLKAIGDIELASKQGT 870
+ E N++ +++L K ++ G L I+ + LT K I
Sbjct 384 RAAEVNSSRNSVLGAGIKSDNSAITRGTLDIKARGQLTAQG-----KNISGTAQTFNANR 438
Query 871 LILAGYGGQAGNGSEKVLNLTTTGGGISLEGASV 904
+ L+G Q+G+ L TT GG I L GA++
Sbjct 439 IDLSGSQTQSGD-----LTFTTEGGDIDLTGANL 467
Score = 30.4 bits (67), Expect = 0.042
Identities = 69/311 (22%), Positives = 113/311 (36%), Gaps = 65/311 (21%)
Query 1309 GNINLYTVQESSSSNEDITKKS---SFSGIKYNTSKTNATRNQISELPGILKADYIGIKA 1365
GN+ + T Q + ++I S + S I S+T A ++ G + IKA
Sbjct 1088 GNLAVSTEQALIAQGQNIAAGSLALAGSQIDLTGSQTQANAISLTAKSGDITLTSAVIKA 1147
Query 1366 DNDV---RLVGTEFEYLQAAKIQAGRNLSLLT-ASTTVTETLKKDKNSVVW-------QS 1414
+ +L T ++ + I S T AS + + L+ DK S++ Q+
Sbjct 1148 ATQLLVTQLAATRSSFIPPSSIPPSSTQSSSTQASASPSAWLRTDKASLIADQLTFDVQA 1207
Query 1415 MQDKGSVTETAQLPRFNGPTPPEFKAAGGLIVQIPIGEKDQNKIEIRDQILILANQPGNE 1474
+ + G V FN P GG I+ + + I+ Q L
Sbjct 1208 LSNLGGVIAQTGATDFNLNLPGYLDNRGGTILS-------KGNVAIQAQGL--------- 1251
Query 1475 YLKQLVNRNDVDWQKVILAQKDWDYKSQGLTGAGAAIIAIIVVMVTAGAGSAVVGALGGS 1534
D D ++ A D K LT AG + + ++ G +L
Sbjct 1252 ---------DSDSGSLLGAGVQSDGK---LTNAGDLAVTVRQDLIAHGQ------SLAAG 1293
Query 1535 ATTLGGSAVVMTQA-----AVTSLATQASVSL------------INNGGDLGKTLKDLGS 1577
A TL GS V +T + +T A + VS IN G + G+TL + G
Sbjct 1294 AMTLTGSGVDLTGSQTQARGITITANKGDVSTQRANILSLGSLAINAGANAGQTLNNQGG 1353
Query 1578 KDSVKNLAASV 1588
N+A ++
Sbjct 1354 SLQANNIALNL 1364
Score = 30.0 bits (66), Expect = 0.055
Identities = 93/456 (20%), Positives = 178/456 (39%), Gaps = 80/456 (18%)
Query 1202 NLVLQATGITAANGDVRIEANKNILFDAAIEQSYDRSTTTEKKSSWGGLKKKYITT-VSE 1260
NL LQA R+ +N L A I+ K+S G L+ +++
Sbjct 690 NLALQAE---------RLTSNSQSLLGAGIQAD-------GSKASKGDLQANTTQALIAQ 733
Query 1261 NNQANAASVDISGKNIFIESKEKNPANNIDIYSGKFIANGGQVSILSGGNINLYTVQESS 1320
A ++ +SG + + + + A+NI I + + ++++ G +++ V
Sbjct 734 GQNVAAGTMTLSGSRVDLTGSQTH-ASNITITARDGDVTTREATLITPGTLSMTAVANPE 792
Query 1321 SSNEDITKKSSFSGIKYNTSKTNATRNQISELPGI---LKADYIG-----IKADNDVRLV 1372
+ + K I+ N +K + +I+ + L++D+I + A D+ L
Sbjct 793 QTLNNRGGKLHADNIQLNLAKLENSNGEIAAATDLWLRLQSDFIHQAGARLTAGRDL-LF 851
Query 1373 GTEFEYLQAAKIQAGRNLSLLTAS---TTVTETLKKDKNSVV--------WQSMQDKGSV 1421
+ + K++AGR++ L S T+ D +S++ S+ ++G++
Sbjct 852 NSRGALINQYKLEAGRDMQLTALSIRNTSADRNTNADNSSLLAGRGLSLSTDSLFNRGAI 911
Query 1422 TETAQLPRF--NGPTPP----------EFKAAGGLIVQIPIGEKDQNKIEIRDQILILAN 1469
T + +F NG T F A G L + + + + ++ + + N
Sbjct 912 YTTG-VGQFTVNGNTENIGEIYTEQQLTFTATGNLANRGVMQTRGEMQLSAQGDV----N 966
Query 1470 QPGNEY-----LKQLVNRNDVDWQKVILAQKDWDYKSQG-------LTGAGAAIIAIIVV 1517
G Y ++ + N + K+ +A + ++G L GAG + I
Sbjct 967 NSGMLYSAGDQMRLSIAGNLTNEGKLHVANGEMRLLTEGNLDNRGSLYGAGNSDITTQGN 1026
Query 1518 MVTAGAGSAVVGALGGSATTLGGSAVVMTQAAVTSLATQASVSLINNGGDLGKTLKDLGS 1577
V G+ GAL T G + AA+ L +A+ L +N + LK GS
Sbjct 1027 AVNTGS-VYTQGAL--QWLTKGSVRNSASIAALGDLQLRANDLLSDNQSLMAAGLKADGS 1083
Query 1578 KDSVKNLAASV----------VTAGLLSQVGSALNL 1603
+ NLA S + AG L+ GS ++L
Sbjct 1084 RSDSGNLAVSTEQALIAQGQNIAAGSLALAGSQIDL 1119
Score = 27.7 bits (60), Expect = 0.27
Identities = 26/94 (28%), Positives = 42/94 (45%), Gaps = 16/94 (17%)
Query 1729 KIRNTGKIVAGVVSAYAGYDVNTAANS---ADIAIQNNSLVK---------LATSTGKIL 1776
K+ N+G + A + +VN++ NS A I N+++ + T+ GK +
Sbjct 368 KLSNSGTVAAAGDTLIRAAEVNSSRNSVLGAGIKSDNSAITRGTLDIKARGQLTAQGKNI 427
Query 1777 VKTLDEFNALR--KAGKQVTKDDLVTSFKKQGAD 1808
T FNA R +G Q DL +F +G D
Sbjct 428 SGTAQTFNANRIDLSGSQTQSGDL--TFTTEGGD 459
Score = 27.3 bits (59), Expect = 0.36
Identities = 42/198 (21%), Positives = 76/198 (38%), Gaps = 13/198 (7%)
Query 1180 KPTLINGDKGVTIRATGN--SNQDNLVLQATGITAANGDVRIEANKNILFDAAIEQS--- 1234
K LI + GV + G ++ ++V+ A G+ G + + + IE S
Sbjct 296 KIRLIGTETGVGVHNAGEIGASAGDIVITADGMLVNRGQISSAQQLAVNTPSGIENSGVL 355
Query 1235 YDRSTTTEKKSSWGGLKKKYITTVSENNQANAASVDISGKNIFIES-KEKNPA---NNID 1290
Y + T + ++ G L + + AA V+ S ++ K N A +D
Sbjct 356 YGKGNT--QLTTAGKLSNSGTVAAAGDTLIRAAEVNSSRNSVLGAGIKSDNSAITRGTLD 413
Query 1291 IYS-GKFIANGGQVS-ILSGGNINLYTVQESSSSNEDITKKSSFSGIKYNTSKTNATRNQ 1348
I + G+ A G +S N N + S + + D+T + I + A R
Sbjct 414 IKARGQLTAQGKNISGTAQTFNANRIDLSGSQTQSGDLTFTTEGGDIDLTGANLFANRRL 473
Query 1349 ISELPGILKADYIGIKAD 1366
P +L+ D + A+
Sbjct 474 SVSTPSLLRTDKANLFAE 491
Score = 27.3 bits (59), Expect = 0.36
Identities = 47/240 (20%), Positives = 94/240 (39%), Gaps = 42/240 (18%)
Query 1187 DKGVTIRATGNSNQDNLVLQATGITAANGDVRIEANKNILFDAAIEQSYDRSTTTEKKSS 1246
++G TI + GN + +QA G+ + +G + + D + + D + T +
Sbjct 1233 NRGGTILSKGN-----VAIQAQGLDSDSGSL---LGAGVQSDGKLTNAGDLAVTVRQD-- 1282
Query 1247 WGGLKKKYITTVSENNQANAASVDISGKNIFIESKEKNPANNIDIYSGKFIANGGQVSIL 1306
++ A ++ ++G + + + A I I AN G VS
Sbjct 1283 ----------LIAHGQSLAAGAMTLTGSGVDLTGSQTQ-ARGITI-----TANKGDVSTQ 1326
Query 1307 SGGNINLYTVQESSSSNEDITKKSSFSGIKYNTSKTNATRNQISELPGILKADY---IGI 1363
++L ++ ++ +N T + ++ N N Q+ G + A +G+
Sbjct 1327 RANILSLGSLAINAGANAGQTLNNQGGSLQANNIALNL--GQLDNRTGKIAASQDLVLGL 1384
Query 1364 KADNDVRLVGTEFEYLQAAKIQAGRNLSLLT--ASTTVTETLKKDKNSVVWQSMQDKGSV 1421
++D F L + +QAGR+ S T A T + L K S S+ + G++
Sbjct 1385 QSD---------FNILADSTLQAGRDFSFTTHGALTNDGQLLAGRKLSTRSNSLLNNGNI 1435
>I1WVY3 tRNA nuclease CdiA-2 [Burkholderia pseudomallei (strain
1026b)]
Length=3122
Score = 280 bits (716), Expect = 5e-78
Identities = 287/1075 (27%), Positives = 470/1075 (44%), Gaps = 151/1075 (14%)
Query 1 MNKNRYRVVYNQARQMFMAVAENVKSQTKTSGQSTASSVTVE--QSQPFHQLWQVKCLVA 58
MNKNRYRVV+N+AR M V EN ++ + + + V PF ++ +
Sbjct 1 MNKNRYRVVFNRARGALMVVQENGRASHGSGSRDARAGVVPAWLSLSPF----ALRHVAL 56
Query 59 SMSLWMPLAPVYAQIQADNSANAGNRPVIGVGQNSQGQNVPVVNIQTP-TNGVSHNIYKQ 117
++ + + P++ Q A + P + QN Q VNI P +GVS N Y Q
Sbjct 57 AVLVAAGVVPIWVNAQV--VAGGAHAPSVIQTQNGLQQ----VNINRPGASGVSMNTYNQ 110
Query 118 MDVLPEGVVLNNSRTGANSSLVGTVGANP-FLAKGEARIILNEVNSSVASRFEGNLEVAG 176
DV G++LNNS + L G +G NP F A AR+I+N+VNS+ S G +E+ G
Sbjct 111 FDVPKPGIILNNSPINVQTQLGGIIGGNPNFQAGDAARLIVNQVNSNNPSFIRGKVEIGG 170
Query 177 QRADVIIANPAGINIKGGGFINANKAILTTGKPQLNADGSIQQFVVDQGKITISANSGSS 236
A ++IAN AG+ + GGGF+N ++A LTTG P DGS+ F V+QG I++
Sbjct 171 AAAQLVIANQAGLVVDGGGFLNTSRATLTTGNPNFGPDGSLTGFNVNQGLISV------- 223
Query 237 LGLGGNKNNADYVDLYARALELNAQLYANKDIQAITGANNISADLQQISTRTGTGTTPTL 296
+G G + N D VDL ARA+++NA+ YA K + + G+N + + + G PT+
Sbjct 224 VGAGLDTANVDQVDLLARAVQINAKAYA-KTLNVVAGSNQVDYNTLNATPIAANGPAPTI 282
Query 297 AIDVKNLGGMYANNIYLLGNEKGLGVSNAG---------TIRAVNNLVVT----SAG--K 341
AIDV LGGMYAN ++L+ +E G+GV+NAG T++A LV++ +AG
Sbjct 283 AIDVSQLGGMYANRVFLVSSENGVGVANAGDIAAQAGDLTLQANGRLVLSGHTNAAGNMS 342
Query 342 IEHKGSLESTSNTQGLVSIQTTQTGDNGNINSSGSITSKSMLSIDAANHLNITGNQVIVN 401
+ G ++++ T G S+ T D + +SG++T++ L+ + + LN TG +
Sbjct 343 LSASGGIQNSGVTYGKQSVTITTGAD---LTNSGALTAQQNLTANVGS-LNSTGT---LG 395
Query 402 QGVVSPLLLSAQGDINVSNGAIIKNVQT---GGDIYLDAQNINVGENTQIAN-------- 450
G+ + GD+NV++ + T G+ +N+ + AN
Sbjct 396 AGINVDSTVGTSGDLNVTSSGQLTATGTNSAAGNATFTGSGVNLSNSATAANGNLALTAT 455
Query 451 VGLVNL-----NAAAAIDIKKSARVKAVNDL-NIIAKQGLSVADANLVAEKGNMNLQSNS 504
G VNL +A A++ + S V VND N+ + G+++ +L + G N Q
Sbjct 456 AGDVNLAGSTVSAKGAVNAQASGTV--VNDRGNLSSGAGMTLGGGSLSNQGGRANSQGPL 513
Query 505 NITLQGTTLDLTKDLNINGTGNVNLSSL--NFSLLN--GSSTLQNINAYSGLNLVWDQTA 560
++ + GT + L+ T +V S++ N L+ G T+ + + + A
Sbjct 514 SVQMAGTVSNQNGMLSSQSTADVRGSAIQNNAGLIQSAGKQTIAGASIDNSAGRLISLNA 573
Query 561 KALPQISGNVTLEA--ANLIDLKGSNLSGKGDLKLQGKALNVGADLTAGKSLNL------ 612
L + A AN+ G + GKGD+ +QG + ++A +L++
Sbjct 574 DGLSVTATGALTNAAGANVSGDPGGVIGGKGDVTVQGNTVTNSGSMSADATLHVIGQSVD 633
Query 613 ----------TAT----------------QSDLILNKTL-NAQGNIDIA--SLDGK--LN 641
T T QS ++ TL N+QG ++ A SL+G LN
Sbjct 634 NGNGALHAGQTTTVDAGNHLSNAGGRVEGQSAVLNGATLDNSQGTVNAATVSLNGTTLLN 693
Query 642 ATGLNATSSQGKLSIF----------GAKDTVLTNSGTVKTTLKGNQGVNVGTISTGNLT 691
G + G +++ G T T+ TTL + G + + G LT
Sbjct 694 HGGTVTQTGTGPMTVAITDTLDNSNNGLIQTRSTDLSLTSTTLINDNGGTITHVGPGTLT 753
Query 692 LQNTVLESQNGAIVVTSEGQ-----NTLTDSIITAKG--NIELFAKDNLTLDGIKSSSQQ 744
+ N N A + S G+ T+ +S +A G + + A D++T G K +S
Sbjct 754 VGNGSGTVSNKAGAIASNGRTVLQGKTIDNSAGSASGQTGLSVNAADSITNLGGKLTSNA 813
Query 745 H-------TALNSKKNIYINSQAGTGDSVNFSST--KITELNSTGTLSLISDKNQNLQNT 795
+ +N + + A T S + S+ KI T T++ + D N QN
Sbjct 814 NVDVTAGGALVNDGGELGSKTAATTIHSASLSNLNGKIVSPTLTATVAGLLD---NSQNG 870
Query 796 RLTGGAILLEAGGTLNTPKVIEFNATGSNLLKNDSKLNSLNGDLSIQTKESLTIDPNI-- 853
+ L A N I +G L L++ NG + LT+ P +
Sbjct 871 DFEANQLALTAANLKNQGGHISQWQSGPTTLAVSGTLDNSNGGVIQTNSTDLTLAPAVLD 930
Query 854 -----HTLKAIGDIELASKQGTLILAGYGGQAGNGSEKVLNLTTTGGGISLEGASVELQG 908
T G + L G L GG G + ++ + G + A + L
Sbjct 931 NSKGTITHGGTGTLTLTPGNGAGALQNTGGTIGTNGQAIVKAGSLDNGSGVIAAKLGLSA 990
Query 909 AQLNAEKNIK-ILANNENIQIISIKNKLNNSK-------LSDSNKLLVDLVEIDN 955
A N + ++ +N + IIS L+N + D++ L + IDN
Sbjct 991 TIAGAMNNTQGLMRSNAALSIIS-NGALSNHQGHIEAGTPGDTSTLSIQAASIDN 1044
Score = 86.3 bits (212), Expect = 5e-19
Identities = 150/667 (22%), Positives = 271/667 (41%), Gaps = 106/667 (16%)
Query 323 SNAGTIRAVNNLVVTSAGKIEHKGSLESTSNTQGLVSIQTTQTGDNGNINSSGSITSKSM 382
+N+GT++A L + G+L+S GL S+ TT GN++ + +
Sbjct 1803 TNSGTVKADTTLALQGKQIDNAFGALQSG----GLTSLDTT-----GNVDLTSANVKAGS 1853
Query 383 LSIDAANHLNI-----TGNQVIVNQGVVSPLLLSAQGDINVSNGAIIKNVQTGGDIYLDA 437
L ++A N L + T +QV + L ++NV+ A IK TGGD +A
Sbjct 1854 LDLNAGNKLILDTATQTTHQVSRDGATSDKTTLGPAANLNVAGDASIK---TGGDFQQNA 1910
Query 438 QNINVGENTQIANVGLVNLNAAAAIDIKKSARVKAVNDLNIIAKQGLSVADANLVAEKGN 497
N+NVG N AN+G N N + ++++ K V N ++ L+ A + V G
Sbjct 1911 GNLNVGGNLN-ANIG-GNWN----LGVQQTGEHKVVQRANGVSDTDLNSATGSTVNVGGK 1964
Query 498 MNLQSNSNITLQGTTLDLTKDLNINGTGNVNL--SSLNFSLLNGSSTLQNINAYSGLNLV 555
+ ++T QG LD + + GNV +S ++ SS Q +Y+
Sbjct 1965 SAIGVGGDLTAQGARLDFGQGGTVAAKGNVTFGAASTTSTINANSSGDQGNRSYAETRHG 2024
Query 556 WDQT--------AKALPQISGNVTLEAANLIDLK--GSNLSGKGDLKL---------QGK 596
DQ L +SG + IDLK +NL GD+ + +
Sbjct 2025 SDQALTGTTVKGGDTLNVVSGKDINVIGSTIDLKKGDANLLAAGDVNVGAVTERHVYNSR 2084
Query 597 ALNVGADLTAGKSLNLTATQSDLILNKTLNAQGNIDIASLDGK-LNATGLNATSSQGKLS 655
+ + + +G + + + + N +L + + I S GK +N G + ++
Sbjct 2085 ETHSRSGVVSGTKIASSQDATSTVANGSLISADGVSIGS--GKDINVQGSTVVGTH-DVA 2141
Query 656 IFGAKDTVLTNSGTVKTTLKGNQGVNVGTISTGNLTLQ--NTVLESQNGAIVVTS----- 708
+ A D +T S + Q + G +S G L+ N+ L QN + VT+
Sbjct 2142 LNAAHDVNITTSQDTSQSSTTYQEQHSGLMSGGGLSFSVGNSKLAQQNQSSSVTNNASTV 2201
Query 709 ---EGQNTL-TDSIITAKGNIELFAKD------NLTLDGIKSSSQQ-HTALNSKKNIYIN 757
+G T+ + + KG+ + KD N+ +D +++Q SK + +
Sbjct 2202 GSVDGNLTVNAGNTLHVKGSDLVAGKDVTGTAANIVVDSATDTTRQAQQQQTSKSGLTVG 2261
Query 758 SQAGTGDSVNFSSTKITELNSTGTLSLISDKNQNLQNTRLTGGAILLEAGGTLNTPKVIE 817
GD++N I+E + + S+ + ++ G + A G L +++
Sbjct 2262 LSGSVGDAIN---NAISETQAARESAKDSNGRASALHSIAAAGDV---AFGGLGAKALLD 2315
Query 818 FNATGSNLLKNDSKLNSLNGDLSIQTKESLTIDPNIHTLKAIGDIELASKQGTLILAGYG 877
A G +++ + S+Q+ E TI ++G+ I AG
Sbjct 2316 -GAKGPQAPSIGVQVSVGSSHSSMQSSEDQTI-----------------QRGSSINAG-- 2355
Query 878 GQAGNGSEKVLNLTTTGGGISLEGASVELQGAQLNAEKNIKILANNENIQIISIKNKLNN 937
GN L TG G +G ++ + G+ +NA N+ ++ANN+ +++ N +
Sbjct 2356 ---GNA-----KLIATGNGTPKDG-NITIAGSNVNA-ANVALIANNQ----VNLVNTTDT 2401
Query 938 SKLSDSN 944
K SN
Sbjct 2402 DKTQSSN 2408
Score = 81.6 bits (200), Expect = 1e-17
Identities = 220/982 (22%), Positives = 340/982 (35%), Gaps = 225/982 (23%)
Query 85 PVIGVGQNSQGQNVPVVNIQTPTNGVSHNIYKQMDVLPEGVVLN--------NSRTGANS 136
P G + G NV I G+ Q+D+L V +N N G+N
Sbjct 203 PNFGPDGSLTGFNVNQGLISVVGAGLDTANVDQVDLLARAVQINAKAYAKTLNVVAGSNQ 262
Query 137 SLVGTVGANPFLAKGEARIILNEVNSSVASRFEGNLEVAGQRADVIIANPAGINIKGGGF 196
T+ A P A G A I +V S + + + + V +AN I + G
Sbjct 263 VDYNTLNATPIAANGPAPTIAIDV-SQLGGMYANRVFLVSSENGVGVANAGDIAAQAGDL 321
Query 197 -INANKAILTTGKPQ------LNADGSIQQFVVDQGKITISANSGSSLGLGGNKNNADYV 249
+ AN ++ +G L+A G IQ V GK +++ +G+ L G +
Sbjct 322 TLQANGRLVLSGHTNAAGNMSLSASGGIQNSGVTYGKQSVTITTGADLTNSGALTAQQNL 381
Query 250 DLYARALELNAQLYANKDIQAITGANNISADLQQISTR--TGTGTTPTLAIDVKNLGGMY 307
+L L A ++ + G S DL S+ T TGT
Sbjct 382 TANVGSLNSTGTLGAGINVDSTVGT---SGDLNVTSSGQLTATGTNSA------------ 426
Query 308 ANNIYLLGNEKGLGVSNAGTIRAVNNLVVTSAGKIEHKGSLESTSNTQGLVSIQTTQT-- 365
A N G+ G+ +SN+ T N + +AG + GS T + +G V+ Q + T
Sbjct 427 AGNATFTGS--GVNLSNSATAANGNLALTATAGDVNLAGS---TVSAKGAVNAQASGTVV 481
Query 366 GDNGNINSSGSITSKSMLSIDAANHLNITGNQVIVNQGVVSPL--LLSAQGDINVSNGAI 423
D GN++S +T + N G + G VS +LS+Q +V AI
Sbjct 482 NDRGNLSSGAGMTLGGGSLSNQGGRANSQGPLSVQMAGTVSNQNGMLSSQSTADVRGSAI 541
Query 424 IKN---VQTGGD---------------IYLDAQNINVGENTQIANVGLVNLNA--AAAID 463
N +Q+ G I L+A ++V + N N++ I
Sbjct 542 QNNAGLIQSAGKQTIAGASIDNSAGRLISLNADGLSVTATGALTNAAGANVSGDPGGVIG 601
Query 464 IKKSARVKAVNDLNIIAKQGLSVADANL-----VAEKGNMNLQSNSNIT----------- 507
K V+ N + G ADA L + GN L + T
Sbjct 602 GKGDVTVQG----NTVTNSGSMSADATLHVIGQSVDNGNGALHAGQTTTVDAGNHLSNAG 657
Query 508 ---------LQGTTLDLTKDLNINGTGNVNLSSLN-FSLLNGSSTLQNI----------- 546
L G TLD N GT N SLN +LLN T+
Sbjct 658 GRVEGQSAVLNGATLD-----NSQGTVNAATVSLNGTTLLNHGGTVTQTGTGPMTVAITD 712
Query 547 ---NAYSGL-------------NLVWDQTAKALPQISGNVTL-EAANLIDLKGSNLSGKG 589
N+ +GL L+ D G +T+ + + K ++ G
Sbjct 713 TLDNSNNGLIQTRSTDLSLTSTTLINDNGGTITHVGPGTLTVGNGSGTVSNKAGAIASNG 772
Query 590 DLKLQGKALNVGADLTAGKS-LNLTATQSDLILNKTLNAQGNIDI--------------- 633
LQGK ++ A +G++ L++ A S L L + N+D+
Sbjct 773 RTVLQGKTIDNSAGSASGQTGLSVNAADSITNLGGKLTSNANVDVTAGGALVNDGGELGS 832
Query 634 ------------ASLDGKLNATGLNATSS----QGKLSIFGAKDTVLT-----NSG---- 668
++L+GK+ + L AT + + F A LT N G
Sbjct 833 KTAATTIHSASLSNLNGKIVSPTLTATVAGLLDNSQNGDFEANQLALTAANLKNQGGHIS 892
Query 669 ---------TVKTTLKGNQGVNVGTISTGNLTLQNTVLESQNGAIVVTSEGQNTLTDSII 719
V TL + G + T ST +LTL VL++ G I G TLT
Sbjct 893 QWQSGPTTLAVSGTLDNSNGGVIQTNST-DLTLAPAVLDNSKGTITHGGTGTLTLT---- 947
Query 720 TAKGNIELFAKDNLTLDGIKSSSQQHTALNSKKNIYINSQAGTGDSVNFSSTKITELNST 779
G + + Q+T N +AG+ D N S +L +
Sbjct 948 ----------------PGNGAGALQNTGGTIGTNGQAIVKAGSLD--NGSGVIAAKLGLS 989
Query 780 GTLSLISDKNQNLQNTRLTGGAILLEAGGTLNTPKVIEFNATGSNLLKNDSKLNSLNGDL 839
T++ + Q L R ++ G N IE G L
Sbjct 990 ATIAGAMNNTQGLM--RSNAALSIISNGALSNHQGHIEAGTPGD------------TSTL 1035
Query 840 SIQTKESLTIDPNIHTLKAIGDIELASKQGTLI-------LAGYGGQAGNGSEKV--LNL 890
SIQ D +H G ++ + G+ I + G G G G + ++
Sbjct 1036 SIQAASIDNTDGAVHD---FGTGKMTVQGGSQIVNSHAGGVDGMGQMTGQGDVTIGAASI 1092
Query 891 TTTGGGISLEGASVELQGAQLN 912
+ T GG L GA++ +QGA L+
Sbjct 1093 SNTQGG-QLMGANLLIQGATLD 1113
Score = 73.2 bits (178), Expect = 5e-15
Identities = 252/1234 (20%), Positives = 434/1234 (35%), Gaps = 160/1234 (13%)
Query 565 QISGNVTLEAANLIDLKGSNLSGKGDLKLQGKALNVGADLTAGKSLN---LTATQSDLIL 621
Q++G L DL+G S L L G + +L G SL+ + A +++I+
Sbjct 1705 QLTGKAVL--GPYTDLQGMYQS----LMLAGAEWSKSLNLPLGMSLSAQQVAALTTNVII 1758
Query 622 NKTLNAQGNIDIASLDGKLNATGLNATSSQGKLSIFGAKDT-VLTNSGTVKT----TLKG 676
+T G + + A NA K+T V TNSGTVK L+G
Sbjct 1759 MQTETVGGQQVLVPVVYLAKADQQNANGPLITAGNIDLKNTQVFTNSGTVKADTTLALQG 1818
Query 677 NQGVNV-GTISTGNLTLQNTVLESQNGAIVVTSEGQNTLTDSIITAKGNIELFAKDNLTL 735
Q N G + +G LT +T G LT + + A G+++L A + L L
Sbjct 1819 KQIDNAFGALQSGGLTSLDTT-------------GNVDLTSANVKA-GSLDLNAGNKLIL 1864
Query 736 DGIKSSSQQ---------HTALNSKKNIYINSQAGTGDSVNFSSTKITELNSTGTLSLIS 786
D ++ Q T L N+ + A +F LN G L+
Sbjct 1865 DTATQTTHQVSRDGATSDKTTLGPAANLNVAGDASIKTGGDFQQ-NAGNLNVGGNLNANI 1923
Query 787 DKNQNLQNTRLTGGAILLEAGGTLNTPKVIEFNATGSNLLKNDSKLNSLNGDLSIQTKES 846
N NL + ++ A G +T +ATGS + + GDL T +
Sbjct 1924 GGNWNLGVQQTGEHKVVQRANGVSDTDL---NSATGSTVNVGGKSAIGVGGDL---TAQG 1977
Query 847 LTID-PNIHTLKAIGDIEL-ASKQGTLILAGYGGQAGN--------GSEKVLNLTTTGGG 896
+D T+ A G++ A+ + I A G GN GS++ L TT GG
Sbjct 1978 ARLDFGQGGTVAAKGNVTFGAASTTSTINANSSGDQGNRSYAETRHGSDQALTGTTVKGG 2037
Query 897 ISLEGASVELQGAQLNAEKNIKILANNENIQIISIKNKLNNSKLSDSNKLLVDLVEIDNK 956
+L S K+I ++ + ++ K D+N L V +
Sbjct 2038 DTLNVVS----------GKDINVIGSTIDL------------KKGDANLLAAGDVNVGAV 2075
Query 957 LKKISINNQYTEL---FLADVKILENAYDIAFNFNPSAYKEDASYRKGSDKDIQFFNEVY 1013
++ N++ T ++ KI + + N S D GS KDI V
Sbjct 2076 TERHVYNSRETHSRSGVVSGTKIASSQDATSTVANGSLISAD-GVSIGSGKDI----NVQ 2130
Query 1014 DGFVKKYSDIIEPNIYSQQLNGTKYSTQISIAVPFGDGDYARKEDILSPNGYFKYKYDQN 1073
V D+ + + ++ ++Q S Y + L G + +
Sbjct 2131 GSTVVGTHDVALNAAHDVNITTSQDTSQSSTT-------YQEQHSGLMSGGGLSFSVGNS 2183
Query 1074 KIRSEINYLSQLNGYEHFSSKLVSNSGSIDITSSKGISISGSELISKKGLVNIEALGALS 1133
K+ + +Q + + +S + S G++ + + + + GS+L++ K + A +
Sbjct 2184 KLAQQ----NQSSSVTNNASTVGSVDGNLTVNAGNTLHVKGSDLVAGKDVTGTAANIVVD 2239
Query 1134 QNYTSTIHGKDNKPKTLGASIIIDGSQDFYDKGNENDQKYRFRTILKPTLINGDKGVTIR 1193
+T + + G ++ + GS IN T
Sbjct 2240 SATDTTRQAQQQQTSKSGLTVGLSGSVG--------------------DAINNAISETQA 2279
Query 1194 ATGNSNQDNLVLQATGITAANGDVRIE--ANKNILFDAAIEQSYDRSTTTEKKSSWGGLK 1251
A ++ N A AA GDV K +L A Q+ SS ++
Sbjct 2280 ARESAKDSNGRASALHSIAAAGDVAFGGLGAKALLDGAKGPQAPSIGVQVSVGSSHSSMQ 2339
Query 1252 KKYITTVSENNQANAASVDISGKNIFIESKEKNPANNIDIYSGKFIANGGQVSILSGGNI 1311
T+ + NA G I + P + +G + N V++++ +
Sbjct 2340 SSEDQTIQRGSSINA-----GGNAKLIATGNGTPKDGNITIAGSNV-NAANVALIANNQV 2393
Query 1312 NLYTVQESSSSNEDITKKSSFSGIKYNTSKTNATRNQISELPGILKADYIGIKADNDVRL 1371
NL ++ + + S G+ T N I + +A G ++D +
Sbjct 2394 NLVNTTDTDKTQSSNSSSGSSVGVSIGT-------NGIGVSASMQRAHGDG---NSDAAI 2443
Query 1372 V-GTEFEYLQAAKIQAGRNLSLLTASTTVTETLKKDKNSVVWQSMQDKGSVTETAQLPRF 1430
T Q A I +G + +++ A+ + + ++ S+QD +V+ Q
Sbjct 2444 QNNTHINASQTATIVSGGDTNVIGANVNANKVVADVGGNLNVASVQDT-TVSAAHQSSAG 2502
Query 1431 NGPTPPEFKAAGGLIVQIPIGEKDQNKIEIRDQILILANQPGNEYLKQLVNRNDVDWQKV 1490
G T + GG G D N + +Q I A G + + + + D +
Sbjct 2503 GGFTISQ--TGGGASFSAQNGHADGNYAGVNEQAGIQAGSGGFD----VTVKGNTDLKGA 2556
Query 1491 ILAQKDWDYKSQGLTGAGAAIIAIIVVMVTAGAGSAVVGALGGSATTLGGSAVVMTQAAV 1550
+A K+ TG +A + GA G +T G + V V
Sbjct 2557 YIASTADASKNSLTTGTLTTSDIENHSHYSANSAGFSAGASVGVSTKAVGPSSVSGSGGV 2616
Query 1551 TSLATQASVSLINNGGDLGKTLKDLGSKDSVKNLAASVVTAGLLSQVGSALNLK------ 1604
T + Q N+ GD T K S ++ T + + A NL
Sbjct 2617 TPMVFQ------NDSGDQSATTKSAVSAGAINITKPGEQTQDVANLNRDATNLNGTVSKT 2670
Query 1605 PDTSGFSARLLN--NFTTAVGSTLVQTAIKGGDLEDNLKVALLAGLAGAMQGELASQIGT 1662
PD ++ + N A G T+ Q G + K A+ A A +G+L + + +
Sbjct 2671 PDVQKMLSQQADTMNAAQAAGQTVSQGI--GLYADGKRKDAIDAAKAAYERGDLVA-MQS 2727
Query 1663 HLDKVDPNVFEYAIHKIAHAAVGCAVAAATKSSCEAGAIGAGVGEIVASLMPDPVNGIEY 1722
++D+ + E + A G A+ AIG G +SL+ I
Sbjct 2728 YIDQA-KSWDEGGASRAGLQATGGALIGGLGGGSVLTAIGGAAGAGTSSLLAGQAEKISK 2786
Query 1723 NEDEKTKIRNTGKIVAGVVSAYAGYDVNTAANSA 1756
+ + T G I A V + G V +A +A
Sbjct 2787 SVGDMTGSSLVGNIAANVAATVGGALVGGSAGAA 2820
Score = 72.8 bits (177), Expect = 6e-15
Identities = 207/957 (22%), Positives = 351/957 (37%), Gaps = 186/957 (19%)
Query 78 SANAGNRPVIGVGQNSQGQNVPVVNIQTPTNGVSHNIYKQMDVLPEGVVLNNSRTGANSS 137
+A A V G S G + + G N + V G V N + ++ S
Sbjct 473 NAQASGTVVNDRGNLSSGAGMTLGGGSLSNQGGRANSQGPLSVQMAGTVSNQNGMLSSQS 532
Query 138 LVGTVG------ANPFLAKGEARIILNEVNSSVASRFEGNLEVAGQRADVIIANPAGINI 191
G A + G+ I +++S N + A + N AG N+
Sbjct 533 TADVRGSAIQNNAGLIQSAGKQTIAGASIDNSAGRLISLNADGLSVTATGALTNAAGANV 592
Query 192 KG--GGFINANKAILTTGKPQLN-----ADGSIQQF--VVDQGKITISANSGSSLGLGGN 242
G GG I + G N AD ++ VD G + A +++ G +
Sbjct 593 SGDPGGVIGGKGDVTVQGNTVTNSGSMSADATLHVIGQSVDNGNGALHAGQTTTVDAGNH 652
Query 243 KNNADYVDLYARALELNAQLYANKD--IQAITGANNISADLQQISTRTGTGTTPTLAIDV 300
+NA + ++ LN N + A T + N + L T T TGT P
Sbjct 653 LSNAGG-RVEGQSAVLNGATLDNSQGTVNAATVSLNGTTLLNHGGTVTQTGTGPMTVAIT 711
Query 301 KNLGGMYANNIYLLGNEKGLGVSNAGTIRAVNNLVVTSAGKIEHKGSLEST-SNTQGLVS 359
L +NN + L +++ L+ + G I H G T N G VS
Sbjct 712 DTLDN--SNNGLIQTRSTDLSLTST-------TLINDNGGTITHVGPGTLTVGNGSGTVS 762
Query 360 IQTTQTGDNGNI--------NSSGSITSKSMLSIDAANHLNITGNQVIVNQGVVSPLLLS 411
+ NG NS+GS + ++ LS++AA+ + G + L+
Sbjct 763 NKAGAIASNGRTVLQGKTIDNSAGSASGQTGLSVNAADSITNLGGK------------LT 810
Query 412 AQGDINVSNGAIIKNVQTGGDIYLDAQNINVGENTQIANVGLVNLNA-----------AA 460
+ +++V+ G + N GG++ T I + L NLN A
Sbjct 811 SNANVDVTAGGALVN--DGGELGSKTAA------TTIHSASLSNLNGKIVSPTLTATVAG 862
Query 461 AIDIKKSARVKAVNDLNIIA----KQGLSVAD----ANLVAEKGNMN------LQSNS-N 505
+D ++ +A N L + A QG ++ +A G ++ +Q+NS +
Sbjct 863 LLDNSQNGDFEA-NQLALTAANLKNQGGHISQWQSGPTTLAVSGTLDNSNGGVIQTNSTD 921
Query 506 ITLQGTTLDLTKD-LNINGTGNVNLSSLNFSLLNGSSTLQNINAYSGLNLVWDQTAKALP 564
+TL LD +K + GTG + L+ N G+ LQN G N
Sbjct 922 LTLAPAVLDNSKGTITHGGTGTLTLTPGN-----GAGALQNTGGTIGTN----------- 965
Query 565 QISGNVTLEAANLIDLKGSNLSGKGDLKLQGKALNVGADLTAGKSLNLTATQSDLILNKT 624
G ++A +L N SG KL A GA + A S +
Sbjct 966 ---GQAIVKAGSL-----DNGSGVIAAKLGLSATIAGAMNNTQGLMRSNAALSIISNGAL 1017
Query 625 LNAQGNIDIASLDGKLNATGLNATS-----------SQGKLSIFGAKDTVLTNSGTV--- 670
N QG+I+ A G + + A S GK+++ G V +++G V
Sbjct 1018 SNHQGHIE-AGTPGDTSTLSIQAASIDNTDGAVHDFGTGKMTVQGGSQIVNSHAGGVDGM 1076
Query 671 -KTTLKGNQGVNVGTIST--------GNLTLQNTVLESQNGAIV----------VTSEGQ 711
+ T +G+ + +IS NL +Q L++ G + V G
Sbjct 1077 GQMTGQGDVTIGAASISNTQGGQLMGANLLIQGATLDNSGGQVGNVANATGDVNVAMSGA 1136
Query 712 NTLTDSIITAKGNIELFAKDNLTLDGIKSSSQQHTALNSKKNIYINSQA----------- 760
T T+ IT+ ++ + A + L G S+ + A+N + + Q
Sbjct 1137 VTNTNGSITSTRDLSVAA--STLLGGGAYSAARDAAINLQGDFTTTPQTQFNIGRDLTFT 1194
Query 761 --GT-GDSVNFSSTKITELNS-----TGTL---SLISDKNQNLQNT-RLTGGAILLEAGG 808
GT +S N S +N+ TG + SL+S + +L N + GG++ ++A G
Sbjct 1195 LPGTFANSANLQSVHNLTVNAGNIVNTGAMTAGSLLSTHSGDLTNYGAMVGGSVAIQASG 1254
Query 809 TLNT--PKVIEFNATGSNLLKNDSKLNSLNGDLSIQTKESLTIDPNIHTLKAIGDIELAS 866
T++ P + + S LL+ + I+ ++ T+ ++ T G
Sbjct 1255 TVSNLGPVALIGASDTSGLLEIVAH--------DIENRDDTTLGDSMPTTTIFG------ 1300
Query 867 KQGTLILAGYGGQAGNGSEKVLNLTTTGGGISLEGASVELQGAQLNAEKNIKILANN 923
G + LAG G+ NG+ L GAS+EL ++ + + + N
Sbjct 1301 -LGKVALAG--GKDANGNYTNAALINNSSAAIQSGASMELHADKVTNTRRVMQTSGN 1354
Score = 57.8 bits (138), Expect = 2e-10
Identities = 185/881 (21%), Positives = 326/881 (37%), Gaps = 109/881 (12%)
Query 328 IRAVNNLVVTSAGKIEHKGSLESTSNTQGLVSIQTTQTG-DNGNINSSGSITSKSMLSID 386
+R V V+ +AG + + + + S+ TQ G NIN G+ S +S++
Sbjct 51 LRHVALAVLVAAGVVPIWVNAQVVAGGAHAPSVIQTQNGLQQVNINRPGA----SGVSMN 106
Query 387 AANHLNITGNQVIVNQGVVSPLLLSAQ-GDINVSNGAIIKNVQTGGDIYLDAQNINVGEN 445
N ++ +I+N SP+ + Q G I N N Q G L +N
Sbjct 107 TYNQFDVPKPGIILNN---SPINVQTQLGGIIGGN----PNFQAGDAARLIVNQVNSNNP 159
Query 446 TQIANVGLVNLNAAAAIDIKKSARVKAVNDLNIIAKQGLSVADANLVAEKGNMNLQSNSN 505
+ I G V + AAA ++ N ++ G + + GN N + +
Sbjct 160 SFIR--GKVEIGGAAA-------QLVIANQAGLVVDGGGFLNTSRATLTTGNPNFGPDGS 210
Query 506 IT----LQGTTLDLTKDLNINGTGNVNLSSLNFSLLNGSSTLQNINAYSGLNLVWDQTAK 561
+T QG + L+ V+L + + N + + +N +G N V T
Sbjct 211 LTGFNVNQGLISVVGAGLDTANVDQVDLLARAVQI-NAKAYAKTLNVVAGSNQVDYNTLN 269
Query 562 ALPQISGNVTLEAANLIDLKGSNLSGKGDLKLQGKALNVG--ADLTAGKSLNLTATQSDL 619
A P + A + G + + L + V D+ A L
Sbjct 270 ATPIAANGPAPTIAIDVSQLGGMYANRVFLVSSENGVGVANAGDIAAQAGDLTLQANGRL 329
Query 620 ILNKTLNAQGNIDIASLDGKLNATGLNATSSQGKLSIFGAKDTVLTNSGTVKTTLKGNQG 679
+L+ NA GN+ + S G + +G+ + GK S+ LTNSG + T + N
Sbjct 330 VLSGHTNAAGNMSL-SASGGIQNSGV----TYGKQSVTITTGADLTNSGAL--TAQQNLT 382
Query 680 VNVGTI-STGNL----TLQNTVLESQNGAIVVTSEGQNTLTDSIITAKGNIELFAKDNLT 734
NVG++ STG L + +TV +G + VTS GQ +TA G T
Sbjct 383 ANVGSLNSTGTLGAGINVDSTV--GTSGDLNVTSSGQ-------LTATGTNSAAGNATFT 433
Query 735 LDGIKSSSQQHTALNSKKNIYINSQAGTGDSVNFSSTKITELNSTGTLSLISDKNQNLQN 794
G+ S+ TA N N+ + + AG + + + +N+ + ++++D+
Sbjct 434 GSGVNLSNSA-TAANG--NLALTATAGDVNLAGSTVSAKGAVNAQASGTVVNDRGNLSSG 490
Query 795 TRLT-GGAILLEAGGTLNTPKVIEFNATGSNLLKNDSKLNSLNGDLSIQTKESL---TID 850
+T GG L GG N+ + G+ +++ NG LS Q+ + I
Sbjct 491 AGMTLGGGSLSNQGGRANSQGPLSVQMAGT--------VSNQNGMLSSQSTADVRGSAIQ 542
Query 851 PNIHTLKAIGDIELA-----SKQGTLILAGYGGQAGNGSEKVLNLTTTG-----GGISLE 900
N +++ G +A + G LI G + + + N GG+
Sbjct 543 NNAGLIQSAGKQTIAGASIDNSAGRLISLNADGLSVTATGALTNAAGANVSGDPGGVIGG 602
Query 901 GASVELQGAQLNAEKNIKILANNENIQIISIKNKLNNSKLSDSNKLLVDLVEIDNKLKKI 960
V +QG N N ++ + + +I N L VD N L
Sbjct 603 KGDVTVQG---NTVTNSGSMSADATLHVIGQSVDNGNGALHAGQTTTVDA---GNHLSNA 656
Query 961 S--INNQYTELFLADVKILE---NAYDIAFNFNPSAYKEDASYRKGSDKDIQFFNEVYD- 1014
+ Q L A + + NA ++ N + G+ + D
Sbjct 657 GGRVEGQSAVLNGATLDNSQGTVNAATVSLNGTTLLNHGGTVTQTGTGPMTVAITDTLDN 716
Query 1015 ---GFVKKYS---DIIEPNIYSQQLNGTKYSTQISIAVPFGDGDYARKEDILSPNG--YF 1066
G ++ S + + + + ++ V G G + K ++ NG
Sbjct 717 SNNGLIQTRSTDLSLTSTTLINDNGGTITHVGPGTLTVGNGSGTVSNKAGAIASNGRTVL 776
Query 1067 KYKYDQNKIRSEINY----LSQLNGYEHFSSKLVSNSGSIDITSSKGISISGSELISKKG 1122
+ K N S ++ + + KL SN+ ++D+T+ + G EL SK
Sbjct 777 QGKTIDNSAGSASGQTGLSVNAADSITNLGGKLTSNA-NVDVTAGGALVNDGGELGSKTA 835
Query 1123 LVNIEALGALSQNYTSTIHGKDNKPKTLGASI--IIDGSQD 1161
I + S ++GK P TL A++ ++D SQ+
Sbjct 836 ATTIHSAS------LSNLNGKIVSP-TLTATVAGLLDNSQN 869
Score = 56.6 bits (135), Expect = 5e-10
Identities = 170/761 (22%), Positives = 279/761 (37%), Gaps = 123/761 (16%)
Query 79 ANAGNRPVIGVG-----QNSQGQNVPVVNIQTPTNGVSHNIYKQMD--VLPEGVVLNNSR 131
A AG+ G+G ++G P + +Q G SH+ + + + G +N
Sbjct 2298 AAAGDVAFGGLGAKALLDGAKGPQAPSIGVQVSV-GSSHSSMQSSEDQTIQRGSSIN--- 2353
Query 132 TGANSSLVGTVGANPFLAKGEARIILNEVNSSVASRFEGNLE--VAGQRADVIIANPAGI 189
G N+ L+ T P G I + VN++ + N V D ++ +
Sbjct 2354 AGGNAKLIATGNGTP--KDGNITIAGSNVNAANVALIANNQVNLVNTTDTDKTQSSNSSS 2411
Query 190 NIKGGGFINANKAILTTGKPQLNADGSIQQFVVDQGKITISANSGSSLGLGGNKNNADYV 249
G I N ++ + + DG+ + Q I+A+ +++ GG+ N
Sbjct 2412 GSSVGVSIGTNGIGVSASMQRAHGDGNSDAAI--QNNTHINASQTATIVSGGDTN----- 2464
Query 250 DLYARALELNAQLYANKDIQAITGANNISADLQQISTRTGTGTTPTLAIDVKNLGG---M 306
+ A + ANK + + G N+ A +Q + ++ + GG
Sbjct 2465 -------VIGANVNANKVVADVGGNLNV-ASVQDTTVSAAHQSSAGGGFTISQTGGGASF 2516
Query 307 YANNIYLLGNEKGLGVSNAGTIRAVNNLVVTSAGKIEHKGS-LESTSNTQGLVSIQTTQT 365
A N + GN G+ AG VT G + KG+ + ST++
Sbjct 2517 SAQNGHADGNYAGVN-EQAGIQAGSGGFDVTVKGNTDLKGAYIASTADA----------- 2564
Query 366 GDNGNINSSGSITSKSMLSIDAANHLNITGN--------QVIVNQGVVSPLLLSAQGDIN 417
S S+T+ ++ + D NH + + N V V+ V P +S G +
Sbjct 2565 -------SKNSLTTGTLTTSDIENHSHYSANSAGFSAGASVGVSTKAVGPSSVSGSGGVT 2617
Query 418 ---VSNGAIIKNVQTGGDIYLDAQNI-NVGENTQ-IANVG--LVNLNAAAA--IDIKKSA 468
N + ++ T + A NI GE TQ +AN+ NLN + D++K
Sbjct 2618 PMVFQNDSGDQSATTKSAVSAGAINITKPGEQTQDVANLNRDATNLNGTVSKTPDVQKML 2677
Query 469 RVKAVNDLNIIAKQGLSVADANLVAEKGNMN--------LQSNSNITLQGTTLDLTKDLN 520
+A + +N G +V+ + G ++ + +D K +
Sbjct 2678 SQQA-DTMNAAQAAGQTVSQGIGLYADGKRKDAIDAAKAAYERGDLVAMQSYIDQAKSWD 2736
Query 521 INGTGNVNLSSLNFSL---LNGSSTLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANL 577
G L + +L L G S L I +G A ++G + ++
Sbjct 2737 EGGASRAGLQATGGALIGGLGGGSVLTAIGGAAG--------AGTSSLLAGQAEKISKSV 2788
Query 578 IDLKGSNLSGKGDLKLQGKALNVGADLTAGKSLNLTATQSDLIL--NKTLNAQGNIDIAS 635
D+ GS+L G + A VG L G + A+ +L N IA
Sbjct 2789 GDMTGSSLVGNIAANV---AATVGGALVGGSAGAAMASNVELYNAGNDPQKTDDRATIAG 2845
Query 636 LDGKLN------ATGL----NATSSQGKLSIFGAKDTVLTNSGT-VKTTLKGNQGVN-VG 683
L G LN A GL NA ++ G +I GA D+ GT +K +G +
Sbjct 2846 LQGLLNQAVAAGAKGLSTIANARNAIGN-AISGALDSAADQFGTLMKRDAEGKMSQSPAE 2904
Query 684 TISTGNLTLQNTVLESQNGAIVVTSEGQNTLTDSIITAKGNIELFAKDNL-TLDGIKSSS 742
+S G NTVL S+ G + DS+ N L A D + I S+S
Sbjct 2905 LVSQGVANGINTVLGSKGGEPPLAGPSA-VAVDSLTGQAANAALGATDRTPPSNAILSNS 2963
Query 743 QQHTALNSKKNIYINSQAGTGDSVNFSSTKITELNSTGTLS 783
NS N SQ+GT TK +TG+LS
Sbjct 2964 ------NSDNNSTQGSQSGT-------VTKTPNPEATGSLS 2991
Score = 45.8 bits (107), Expect = 9e-07
Identities = 144/775 (19%), Positives = 289/775 (37%), Gaps = 85/775 (11%)
Query 77 NSANAGNRPVIGVGQNSQGQNVPVVNIQTPTNGVSHNIYKQMDVLPEGVVLNNSRTGANS 136
++ N G + IGVG + Q + Q T N+ + N+S N
Sbjct 1957 STVNVGGKSAIGVGGDLTAQGARLDFGQGGTVAAKGNVTFGAASTTSTINANSSGDQGNR 2016
Query 137 SLVGTVGANPFLAKG---EARIILNEVNSSVASRFEGNLEVAGQRADVIIANPAGINIKG 193
S T + G + LN V+ ++ V G D+ N+
Sbjct 2017 SYAETRHGSDQALTGTTVKGGDTLNVVSGK-------DINVIGSTIDL---KKGDANLLA 2066
Query 194 GGFINANKAILTTGKPQLNADGSIQQFVVDQGKITISANSGSSLGLGGNKNNADYVDLYA 253
G +N T + N+ + + V G S+ +S G+ +AD V +
Sbjct 2067 AGDVNVGAV---TERHVYNSRETHSRSGVVSGTKIASSQDATSTVANGSLISADGVSI-G 2122
Query 254 RALELNAQ---LYANKDIQAITGANNISADLQQISTRTGTGTTPTLAIDVKNLGGM---Y 307
++N Q + D+ A+ A++++ Q ++++ T T + + GG+
Sbjct 2123 SGKDINVQGSTVVGTHDV-ALNAAHDVNITTSQDTSQSST-TYQEQHSGLMSGGGLSFSV 2180
Query 308 ANNIYLLGNEKGLGVSNAGTIRAVN-NLVVTSAGKIEHKGS-LESTSNTQGLVSIQTTQT 365
N+ N+ +NA T+ +V+ NL V + + KGS L + + G + +
Sbjct 2181 GNSKLAQQNQSSSVTNNASTVGSVDGNLTVNAGNTLHVKGSDLVAGKDVTGTAANIVVDS 2240
Query 366 GDNGNINSSGSITSKSMLSIDAANHLNITGNQVIVNQGVVSPLLLSAQGDINVSNG--AI 423
+ + TSKS L++ + + N I +A+ SNG +
Sbjct 2241 ATDTTRQAQQQQTSKSGLTVGLSGSVGDAINNAISE-------TQAARESAKDSNGRASA 2293
Query 424 IKNVQTGGDIYLDAQNINVGENTQIANVGLVNLNAAAAIDIKKSARVKAVNDLNIIAKQG 483
+ ++ GD V L A A +D K + ++ +
Sbjct 2294 LHSIAAAGD------------------VAFGGLGAKALLDGAKGPQAPSIGVQVSVGSSH 2335
Query 484 LSVADANLVAEKGNMNLQSNSNITLQGTTLDLTKDLNINGTGNVNLSSLNFSLLNGSSTL 543
S+ + + ++ + N L T KD NI G+ N+++ N +L+ +
Sbjct 2336 SSMQSSEDQTIQRGSSINAGGNAKLIATGNGTPKDGNITIAGS-NVNAANVALIANN--- 2391
Query 544 QNINAYSGLNLVWDQTAKALPQISGNVTLEAANLIDLKGSNLSGKGDLKLQGKALNVGAD 603
+N + + Q++ + S V++ N I + S GD A+
Sbjct 2392 -QVNLVNTTDTDKTQSSNSSSGSSVGVSI-GTNGIGVSASMQRAHGDGN-SDAAIQNNTH 2448
Query 604 LTAGKSLNLTATQSDLILNKTLNAQGNIDIASLDGKLNATGLNAT--SSQGKLSIFGAKD 661
+ A ++ + + ++ +NA N +A + G LN + T S+ + S G
Sbjct 2449 INASQTATIVSGGDTNVIGANVNA--NKVVADVGGNLNVASVQDTTVSAAHQSSAGGGFT 2506
Query 662 TVLTNSGTVKTTLKGNQGVNVGTISTGNLTLQNTVLESQNGAIVVTSEGQNTLTDSIITA 721
T G + G+ N ++ + +++ +G VT +G L + I +
Sbjct 2507 ISQTGGGASFSAQNGHADGNYAGVN------EQAGIQAGSGGFDVTVKGNTDLKGAYIAS 2560
Query 722 KGNIELFAKDNLTLDGIKSS---SQQHTALNSKKNIYINSQAGTGDSVNFSSTKITELNS 778
+ +K++LT + +S + H + NS AG V+ + + ++
Sbjct 2561 TADA---SKNSLTTGTLTTSDIENHSHYSANS-----AGFSAGASVGVSTKAVGPSSVSG 2612
Query 779 TGTLSLISDKNQNLQNTRLTGGAILLEAGGTLNTPKVIEFNATGSNLLKNDSKLN 833
+G ++ + +N + + T A+ + G +N K E +NL ++ + LN
Sbjct 2613 SGGVTPMVFQNDSGDQSATTKSAV---SAGAINITKPGEQTQDVANLNRDATNLN 2664
Score = 40.0 bits (92), Expect = 5e-05
Identities = 158/738 (21%), Positives = 261/738 (35%), Gaps = 104/738 (14%)
Query 1099 SGSIDITSSKGISISGSE-------LISKKGLVNIEALGALSQNYTSTIHGKDNKPKTLG 1151
+G++ +++S GI SG + + L N AL A QN T+ + G N TLG
Sbjct 338 AGNMSLSASGGIQNSGVTYGKQSVTITTGADLTNSGALTA-QQNLTANV-GSLNSTGTLG 395
Query 1152 ASIIIDGSQDFYDKGNENDQKYRFRTILKPTLINGDKGVTIRATGNSNQDNLVLQATG-- 1209
A I +D + G D L T N G N N A G
Sbjct 396 AGINVDSTV-----GTSGDLNVTSSGQLTATGTNSAAGNATFTGSGVNLSNSATAANGNL 450
Query 1210 -ITAANGDVRIEANKNILFDAAIEQSYDRSTTTEKK--SSWGGLKKKYITTVSENNQANA 1266
+TA GDV + A + A+ + ++ SS G+ + ++ +AN+
Sbjct 451 ALTATAGDVNL-AGSTVSAKGAVNAQASGTVVNDRGNLSSGAGMTLGGGSLSNQGGRANS 509
Query 1267 A---SVDISGKNIFIESKEKNPANNIDIYSGKFIANGGQVSILSGGNINLYTVQESSSSN 1323
SV ++G + ++ + + D+ N G + S G + +S+
Sbjct 510 QGPLSVQMAG-TVSNQNGMLSSQSTADVRGSAIQNNAGLIQ--SAGKQTIAGASIDNSAG 566
Query 1324 EDITKKSSFSGIKYNTSKTNATRNQISELPGIL---KADYI----------GIKADNDVR 1370
I+ + + + TNA +S PG + K D + AD +
Sbjct 567 RLISLNADGLSVTATGALTNAAGANVSGDPGGVIGGKGDVTVQGNTVTNSGSMSADATLH 626
Query 1371 LVGTEFEYL-------QAAKIQAGRNLSLLTASTTVTETLKKDKNSVVWQSMQDKGSVTE 1423
++G + Q + AG +LS A V + +++V+ + D T
Sbjct 627 VIGQSVDNGNGALHAGQTTTVDAGNHLS--NAGGRV-----EGQSAVLNGATLDNSQGTV 679
Query 1424 TAQLPRFNGPTPPEFKAAGGLIVQIPIG-----------EKDQNKIEIRDQILILANQPG 1472
A NG T GG + Q G + I+ R L L +
Sbjct 680 NAATVSLNGTT---LLNHGGTVTQTGTGPMTVAITDTLDNSNNGLIQTRSTDLSLTSTTL 736
Query 1473 NEYLKQLVNRNDVDWQKVILAQKDWDYKSQGLTGAGAAIIAIIVVMVTAGAGSAVVGA-- 1530
+ V K+ + G ++ + +AG+ S G
Sbjct 737 INDNGGTITHVGPGTLTVGNGSGTVSNKAGAIASNGRTVLQGKTIDNSAGSASGQTGLSV 796
Query 1531 -LGGSATTLGGSAVVMTQAAVTSLATQASVSLINNGGDLG-KTLKDLGSKDSVKNLAASV 1588
S T LGG VT A +L+N+GG+LG KT S+ NL +
Sbjct 797 NAADSITNLGGKLTSNANVDVT-----AGGALVNDGGELGSKTAATTIHSASLSNLNGKI 851
Query 1589 VT-------AGLL--SQVG---------SALNLKPDTSGFSARLLNNFTTAVGSTLVQTA 1630
V+ AGLL SQ G +A NLK S T AV TL +
Sbjct 852 VSPTLTATVAGLLDNSQNGDFEANQLALTAANLKNQGGHISQWQSGPTTLAVSGTLDNS- 910
Query 1631 IKGGDLEDNLKVALLAGLAGAMQGELASQIGTHLDKVDPNVFEYAIHKIAHAAVGCAVAA 1690
GG ++ N LA + GT + P A+ G +
Sbjct 911 -NGGVIQTNSTDLTLAPAVLDNSKGTITHGGTGTLTLTPGNGAGALQN-----TGGTIGT 964
Query 1691 ATKSSCEAGAIGAGVGEIVASL-MPDPVNGIEYNEDEKTKIRNTGKIVA-GVVSAYAGY- 1747
++ +AG++ G G I A L + + G N + I++ G +S + G+
Sbjct 965 NGQAIVKAGSLDNGSGVIAAKLGLSATIAGAMNNTQGLMRSNAALSIISNGALSNHQGHI 1024
Query 1748 DVNTAANSADIAIQNNSL 1765
+ T +++ ++IQ S+
Sbjct 1025 EAGTPGDTSTLSIQAASI 1042
Score = 38.5 bits (88), Expect = 1e-04
Identities = 98/481 (20%), Positives = 180/481 (37%), Gaps = 87/481 (18%)
Query 133 GANSSLVGTVGANPFLAKGEARIILNEVNSS---VASRFEGNLEVAGQRADV--IIANPA 187
GA + GT+G N G+A + +++ +A++ + +AG + ++ + A
Sbjct 953 GALQNTGGTIGTN-----GQAIVKAGSLDNGSGVIAAKLGLSATIAGAMNNTQGLMRSNA 1007
Query 188 GINIKGGGFINANKAILTTGKPQL------------NADGSIQQF-----VVDQGKITIS 230
++I G ++ ++ + G P N DG++ F V G ++
Sbjct 1008 ALSIISNGALSNHQGHIEAGTPGDTSTLSIQAASIDNTDGAVHDFGTGKMTVQGGSQIVN 1067
Query 231 ANSGSSLGLGGNKNNADYVDLYARALELNAQLYANKDIQAITGANNI--SADLQQISTRT 288
+++G G+G D + + A +N + GAN + A L +
Sbjct 1068 SHAGGVDGMGQMTGQGD--------VTIGAASISNTQGGQLMGANLLIQGATLDNSGGQV 1119
Query 289 GTGTTPTLAIDVKNLGGMYANNIYLLGNEKGLGVSNAGTIRAVNNLVVTSAGKIEHKGSL 348
G T ++V + G N + + + L V+ A T+ I +G
Sbjct 1120 GNVANATGDVNVA-MSGAVTNTNGSITSTRDLSVA-ASTLLGGGAYSAARDAAINLQGDF 1177
Query 349 ESTSNTQGLVSIQTTQTGDNGNINSSGSITSKSMLSIDAANHLNITGNQVIVNQGVVSP- 407
+T TQ + T T G +S ++ S L+++A N IVN G ++
Sbjct 1178 TTTPQTQFNIGRDLTFTLP-GTFANSANLQSVHNLTVNAGN---------IVNTGAMTAG 1227
Query 408 -LLLSAQGDINVSNGAIIKNVQTGGDIYLDAQNINVGENTQIANVGLVNLNAAAAIDIKK 466
LL + GD+ + GA++ GG + + A G + + V L+ + + +
Sbjct 1228 SLLSTHSGDLT-NYGAMV-----GGSVAIQAS----GTVSNLGPVALIGASDTSGL---- 1273
Query 467 SARVKAVNDLNIIAKQGLSVADANLVAEKGNMNLQSNSNITLQGTTLDLTKDLNINGTGN 526
L I+A + D L + + L G KD N N T
Sbjct 1274 ---------LEIVAHDIENRDDTTLGDSMPTTTIFGLGKVALAGG-----KDANGNYT-- 1317
Query 527 VNLSSLNFSLLNGSSTLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANLIDLKGSNLS 586
N +L+N SS A L+ + + Q SGN + L+ G ++S
Sbjct 1318 ------NAALINNSSAAIQSGASMELHADKVTNTRRVMQTSGNTSQVDPALLQQLGISMS 1371
Query 587 G 587
G
Sbjct 1372 G 1372
Score = 26.2 bits (56), Expect = 0.80
Identities = 26/97 (27%), Positives = 39/97 (40%), Gaps = 22/97 (23%)
Query 1508 GAAIIAIIVVMVTAGAGSAVVGALGGSATTLGGSAVVMTQAAVTSLATQASVSLINNGGD 1567
G++++ I V A G A+VG G+A ++V L N G D
Sbjct 2793 GSSLVGNIAANVAATVGGALVGGSAGAAMA-------------------SNVELYNAGND 2833
Query 1568 LGKTLKDLGSKDSVKNLAASVVTAGL--LSQVGSALN 1602
KT D + ++ L V AG LS + +A N
Sbjct 2834 PQKT-DDRATIAGLQGLLNQAVAAGAKGLSTIANARN 2869
Score = 25.8 bits (55), Expect = 1.0
Identities = 35/146 (24%), Positives = 59/146 (40%), Gaps = 14/146 (10%)
Query 1523 AGSAVVGALGGSATTLGGSAVVMT--QAAVTSLATQASVSLINNGGDLGK---------T 1571
A + + A G T +V++ A +++ AS + N+G GK
Sbjct 309 ANAGDIAAQAGDLTLQANGRLVLSGHTNAAGNMSLSASGGIQNSGVTYGKQSVTITTGAD 368
Query 1572 LKDLGSKDSVKNLAASVVTAGLLSQVGSALNLKPDTSGFSARLLNNFTTAVGSTLVQTAI 1631
L + G+ + +NL A+V + +G+ +N+ T G S L N T++ T T
Sbjct 369 LTNSGALTAQQNLTANVGSLNSTGTLGAGINV-DSTVGTSGDL--NVTSSGQLTATGTNS 425
Query 1632 KGGDLEDNLKVALLAGLAGAMQGELA 1657
G+ L+ A A G LA
Sbjct 426 AAGNATFTGSGVNLSNSATAANGNLA 451
>D5CBA0 16S rRNA endonuclease CdiA [Enterobacter cloacae subsp.
cloacae (strain ATCC 13047 / DSM 30054 / NBRC 13535 / NCTC
10005 / WDCM 00083 / NCDC 279-56)]
Length=3321
Score = 254 bits (650), Expect = 3e-70
Identities = 270/920 (29%), Positives = 413/920 (45%), Gaps = 119/920 (13%)
Query 54 KCLVASMSLWMPLAPVYAQIQADNSANAGNRPVIGVGQNSQGQNVPVVNIQTPT-NGVSH 112
+ L A +S+ + P+ + A + + + + VPVVNI TP +G+SH
Sbjct 12 RALSALLSVLLATQPLLPAVAASITPSGNTQ------MDKAANGVPVVNIATPNQSGISH 65
Query 113 NIYKQMDVLPEGVVLNNSRTGANSS-LVGTVGANPFLAKG-EARIILNEVNSSVASRFEG 170
N Y +V EG++LNN+ N + L G + NP L G EA+ I+NEV + S +G
Sbjct 66 NKYNDYNVGKEGLILNNATGQLNQTQLGGLIQNNPNLKAGQEAKGIINEVTGANRSNLQG 125
Query 171 NLEVAGQRADVIIANPAGINIKGGGFINANKAILTTGKPQLNADGSIQQFVVDQGKITIS 230
EVAG+ A+VI+ANP GI G GFIN LTTGKP L+A G +Q V QG +TI
Sbjct 126 YTEVAGKAANVIVANPYGITCNGCGFINTPNVTLTTGKPVLDASGKLQSLDVTQGAVTIE 185
Query 231 ANSGSSLGLGGNKNNADYVDLYARALELNAQLYANKDIQAITGANNISADLQQISTRTGT 290
G G N + +D V + +RA E+N QL+A KD++ + GAN ++AD +S G
Sbjct 186 -------GAGLNGSQSDAVSIISRATEINVQLHA-KDLRVVAGANRVAAD-GSVSALKGE 236
Query 291 GTTPTLAIDVKNLGGMYANNIYLLGNEKGLGVSNAGTIRA-VNNLVVTSAGKIEHKGSLE 349
GT P +A+D LGGMYAN I L+ +E G+GV N G + A ++ ++SAGK+ K +L
Sbjct 237 GTAPKVAVDTGALGGMYANRIRLVSSETGVGV-NLGNLNARQGDIALSSAGKVVLKNTLA 295
Query 350 STSNTQGLVSIQTTQTGDN---GNINSSGSITSKSMLSIDAANHLNITGNQVIVNQGVVS 406
S S T + T GD+ GN+ SG ++ L++D A H+ N
Sbjct 296 SGSTTVSAADV--TLRGDHKAGGNVTVSG----QTALTLDQA-HVAADNN---------- 338
Query 407 PLLLSAQGDINVSNGAIIKNVQTGGDIYLDAQNINVGENTQIANVGLVNLNAAAAIDIKK 466
L L+ +G + + GA + A + + T I + V+ A+A +
Sbjct 339 -LQLTTRGTLTQNGGA-----------FTAANDATLAATTLIQS---VDAQASAGRHLAV 383
Query 467 SARVKAVNDLNIIAKQGLSVADANLVAEKGNMNLQSNSNITLQGTTLDLTKDLNINGTGN 526
+A A + +++A Q LSV LV ++GN+ S S I L TL N +GN
Sbjct 384 NAEKNAALNGSVVAGQQLSVKGGELV-QQGNL---SASEIALNAQTLTQESRSTTNASGN 439
Query 527 VNLSSLNFSLLNGSSTLQNINAYSGLNLVWDQTAKALPQ------ISGNVTLEAANLIDL 580
+ L++ S L GS+T A S +L A+ I N N + +
Sbjct 440 ITLTTSGHSQLKGSTTAGQSLAVSAGSLANHGALAAVADTRINTGIFSNTGTVQGNSLTV 499
Query 581 KGSNLSGKGDLKLQGKALNVGAD---------------LTAGKSLNLTATQ-SDLILNKT 624
G++++ G LK L++ AD +TA +LN + T SD L T
Sbjct 500 SGTDITSSGALK-SASTLDIRADNATLSGETGAKGKTTVTASGNLNNSGTLISDDTL--T 556
Query 625 LNAQGNIDIASLDGKLNATGLNATSSQGKLSIFGAKDTVLTNSGTVKTTLKGNQGVNVGT 684
LNA ++ +L G T T + S+ + V N+ TTL G G
Sbjct 557 LNAAQIVNSGTLSGVRGLTTSGKTFTASATSVTQSDGDVALNN--TDTTLAGETSAG-GA 613
Query 685 ISTGNLTLQNTVLESQNGAIVVTSEGQNTLTDSIITAKGNIELFAKDNLTLDGIKSSSQQ 744
++ +L NT +Q V QN + AKGN+ L A +L G S+S
Sbjct 614 VTVQGRSL-NTTATAQTQGNSVGVAVQNAKLEGTQAAKGNMTLKADSSLNHTGKSSAS-- 670
Query 745 HTALNSKKNIYINSQAGTGDSVNFSSTKITE---LNSTGTLSLISDKNQNLQNTRLTGGA 801
L + NS T ++ S ++ +++ TLSL++ N + L +
Sbjct 671 --GLKVETGHLSNSGTLTASALVIDSPEVINGGLIHAGQTLSLVTRLLDNRSSGVLYSPS 728
Query 802 ILLEAGGTLNTPKVIEFNA----TGSNLLKN------------DSKLNSLNGDLSIQTKE 845
L + LN +I +A +GSNL + ++ NS G L Q
Sbjct 729 ALSLSLSELNNAGIITSDAALSLSGSNLTNSGELSGTSLAIDYETLKNSAEGMLLAQGAN 788
Query 846 SLTIDPNIHTLKAIGDIELASKQGTLILAG--YGGQAGNGSEKVLNL-----TTTGGGIS 898
+T +G+ L L AG G A + + +LNL T TGG +
Sbjct 789 RITAQSVSSAGSMVGN-TLTLNADRLESAGLLQGDSALSLTAGILNLLTGSRTLTGGALG 847
Query 899 LEGASVELQGAQLNAEKNIK 918
L G ++ G + +I+
Sbjct 848 LSGTTLTTAGQLQGQDVSIR 867
Score = 84.3 bits (207), Expect = 2e-18
Identities = 177/815 (22%), Positives = 330/815 (40%), Gaps = 161/815 (20%)
Query 178 RADVIIANPAGINIK-----GGGFINANKAILTTGKPQLNA-DGSIQQFVVDQGKITISA 231
R+ ++ +P+ +++ G I ++ A+ +G N+ + S +D + SA
Sbjct 719 RSSGVLYSPSALSLSLSELNNAGIITSDAALSLSGSNLTNSGELSGTSLAIDYETLKNSA 778
Query 232 NSGSSLGLGGNKNNADYVD----LYARALELNAQLYANKDIQAITGANNISADLQQISTR 287
G L G N+ A V + L LNA + + A +++A + + T
Sbjct 779 E-GMLLAQGANRITAQSVSSAGSMVGNTLTLNADRLESAGLLQGDSALSLTAGILNLLTG 837
Query 288 TGTGTTPTLAIDVKNLGGMYANNIYLLGNEKGLGVS-------NAGTIRAVNNLVVTSAG 340
+ T T L G+ + G +G VS N G+ A +L VT+AG
Sbjct 838 SRTLTGGAL--------GLSGTTLTTAGQLQGQDVSIRSHDWTNRGSSLATGSLDVTTAG 889
Query 341 KIEHKGSLESTSNTQGLVSIQTTQTGDNGNINSSG--SITSKSMLSIDAANHLNITGNQ- 397
+ + G L S QG ++ T ++GN+ S+G S+ K++ + +T +Q
Sbjct 890 TLSNTGELMS----QGNGTLNAVTTVNSGNMLSAGDLSLNGKTLRNSGTLQGNRVTAHQD 945
Query 398 VIVNQGV---VSPLLLSAQGD--------INVSNGAIIKNVQ---TGGDIYLDAQNINVG 443
I N G ++ L+L+A+ + +N ++G+++ + TGGD+ +N
Sbjct 946 TITNSGTLTGIAALMLAARLEMAAPLLTLVNDASGSLLTAGELSVTGGDL----RNAGQW 1001
Query 444 ENTQIANVGLVNLNAAAAIDIKKSARVKAVNDLNIIAKQGLSVADANLVAEKGNMNLQSN 503
+ ++ L++ A + ++A N L+ L+ + + G + L
Sbjct 1002 QGKRV----LIHAQA-----LTNGGAIQAENLLDAQIDSTLTGTAGSKITSNGELAL--- 1049
Query 504 SNITLQGTTLDLTKDLNINGTGNVNLSSLNFSLLNGSSTLQNINAYSGLNLVWDQTAKAL 563
S +TL + + K L + G+STL N +G+ + +
Sbjct 1050 SALTLANSGQWIAKHLTL-----------------GASTLNNSGEITGVVALSVALTQLN 1092
Query 564 PQISGNVTLEAANLIDLKGSNLSGKGDLKLQGKALNVGADLTAGKSLNLTATQSDLILNK 623
Q G + A +D++ + +G ++QGKA V TAG+ +N Q + +
Sbjct 1093 NQAGGKLLSAGALTLDVENATNAG----QIQGKATTV----TAGQLINSGRLQGEAL--- 1141
Query 624 TLNAQGNIDIASLDGKLNATGLNAT----SSQGKLSIFGAKD----TVLTNSGTV----K 671
TLNA G ++ + L+ L + ++QG L G T + N G + K
Sbjct 1142 TLNASGALNNTASGVLLSENALTVSTATLNNQGTLQGGGESSVKATTRVQNDGKMLSGGK 1201
Query 672 TTLKGNQGVNVGTISTGNLTLQNTVLESQNGAIVVTS----------EGQNTLTDSIITA 721
TL + N + + L V+++ NG V+ + + TL + + A
Sbjct 1202 LTLTAPELANSSSGLVQAVRLLLDVVKAVNGGNVLATTRAELRGSSLDNSGTLQGADLQA 1261
Query 722 K-----GNIELFAKDNLTLDGIKSSSQQHTALNS--KKNIYINSQAGTGDSVNFSSTKIT 774
+ + +LT++G + + L S K + + + +G GD V+ T +
Sbjct 1262 NYQSVTNSGTVLGTTSLTINGDALDNTESGKLYSGDKLLLDVRNYSGRGDVVSLGDTTLK 1321
Query 775 ELN---STGTLSL-----ISDKNQNLQNTRLTGGAILLEAGGTLNTPKVIEFNATGSNLL 826
+N +TGTL+ +S +N + + G AI L AGG
Sbjct 1322 LVNALVNTGTLAASKTLSVSSQNAMTNSGVMQGNAIALSAGGAFT--------------- 1366
Query 827 KNDSKLNSLNGDLSIQTKESLTIDPNIHTLKAIGDIELASKQGTLILAGYGGQAGNGSEK 886
N+ L + NG S +SL ++ + +L+A GD++L S++ + NG
Sbjct 1367 -NNGTLTTGNGS-STFNAQSLLLNAS-GSLQAGGDVQLTSRENITV---------NG--- 1411
Query 887 VLNLTTTGGGISLEGASVELQGAQLNAEKNIKILA 921
T T G +++ A L A + A NI + A
Sbjct 1412 ---FTGTAGSLTMTAAGTLLNTALIYAGNNISLFA 1443
Score = 82.4 bits (202), Expect = 7e-18
Identities = 143/670 (21%), Positives = 276/670 (41%), Gaps = 127/670 (19%)
Query 351 TSNTQGLVSIQTTQTGDNGNINSSGSITSKSMLSIDAANHLNITGNQVIVNQGVVSP--- 407
T ++ ++S Q INS +I +++ LSID++N L+ +N G++S
Sbjct 1984 TVHSGSVISGNNVQLAGGNVINSGSTIAAQNGLSIDSSNSLS------NLNAGLLSAGGG 2037
Query 408 LLLSAQGDINVSNGAIIKNVQTGGDIYLDAQNINVGENTQIANVGLVNLNAAAAIDIKKS 467
L LSA GDIN + G+ I G + A +IN Q NV N++ + D+ K+
Sbjct 2038 LNLSALGDIN-NIGSTISGKTVG--LESVAGSINNITRAQQWNVDAGNVHFSGT-DVGKT 2093
Query 468 ARVKAVNDLNIIAKQGLSVADANLVAEKGNMNLQSNSNITLQGTTLDLTKDLNINGTGNV 527
A + A + L + A Q ++V AN+ A G +L + +IN T N
Sbjct 2094 ASITATDGLTMRAGQDINVTGANVSA----------------GGSLGMAAGNDINITANE 2137
Query 528 NLSSLNFSLLNGSSTLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANLIDLKGSNLSG 587
++S + N ++T + G L ++TL+A N ++ + + ++
Sbjct 2138 IVTSEGRAGRNRATTETASVTHQGSTL----------SAGDDLTLQAGNDVNARAAAIAA 2187
Query 588 KGDLKLQGKALNVGADLTAGKSLNLTATQS--DLILNKTLNAQGNIDIASLDGKLNATGL 645
+GD+ +Q DL A S+ +++Q+ +++++ QG +IAS + G
Sbjct 2188 EGDVGIQA---GRDVDLLAEASMERSSSQAKKKTAIDESVRQQGT-EIASGGNTVILAGR 2243
Query 646 NAT------SSQGKLSIFGAKDTVLTNSGTVKTTLKGNQGVNVGTISTGNL-TLQNTVLE 698
+ T ++QG + + +D LT + + + G +S T++
Sbjct 2244 DVTAQAADVTAQGDIGVAAGRDVNLTTATESDYRYREQTKTSSGFLSKKTTHTIEEESAT 2303
Query 699 SQNGAI-----VVTSEGQN-TLTDSIITAKGNIELFAKDNLTL----------------- 735
+ G++ V S G N + S + G++ L A +N+ +
Sbjct 2304 REKGSLLSGDNVTVSAGNNLRVLGSAVAGDGDVALSAGNNVDIVAATNTDTAWRFKETKK 2363
Query 736 DGIKSSSQQHTALNSKKNIYINSQAGTGDSVNFSSTKITELNSTGTLSLISDKNQNL--- 792
G+ + + S K+ + + GT S +FS+ T G +S+ + K ++
Sbjct 2364 SGLMGTGGIGFTIGSSKSTHDLREQGTTQSESFSTVGST----GGNVSIAAGKQAHIGGA 2419
Query 793 -----QNTRLTGGAILLEAGGTLNT-PKVIEFNATG---------------------SNL 825
++ LTG ++++E G T + E ++G S
Sbjct 2420 DIIAQKDISLTGDSVVIEPGHDKRTRDEKFEQKSSGLTVALSGAAGSAVNNAVTTAQSAK 2479
Query 826 LKNDSKLNSLNGDLS----IQTKESLTIDPNIHTLKAIGDIELASKQGTLILAGYGGQAG 881
+DS+L +L G + +Q +++ +D + GD + + + A G Q+
Sbjct 2480 QSSDSRLAALQGTQAALSGVQAGQAVALD------QVKGDSDKRNNNTIGVSASIGSQSS 2533
Query 882 NGSEKVLNLTTTGGGIS--------LEGASVELQGAQLNAEKNIKILANNENIQIISIKN 933
S + + TTTG +S G+ + + G+Q+ A K++ + A + I S
Sbjct 2534 KSSSHMESETTTGSTLSAGNNVTIKATGSDITVAGSQIKAGKDVTLDAARDVNLIASQDT 2593
Query 934 KLNNSKLSDS 943
+ K S S
Sbjct 2594 QQTTGKNSSS 2603
Score = 73.6 bits (179), Expect = 4e-15
Identities = 244/1184 (21%), Positives = 437/1184 (37%), Gaps = 230/1184 (19%)
Query 750 SKKNIYINSQAG-TGDSVNFSSTKITELNSTGTLSLISDKNQNLQNTRLTGGAILLEAGG 808
S K++ ++S + +G++V + + +NS T++ + + + N+ A LL AGG
Sbjct 1979 SPKDVTVHSGSVISGNNVQLAGGNV--INSGSTIAAQNGLSIDSSNSLSNLNAGLLSAGG 2036
Query 809 TLNTPKVIEFNATGSNLLKNDSKLNSLNGDLSIQTK-ESLTIDP-NIH------------ 854
LN + + N GS + L S+ G ++ T+ + +D N+H
Sbjct 2037 GLNLSALGDINNIGSTISGKTVGLESVAGSINNITRAQQWNVDAGNVHFSGTDVGKTASI 2096
Query 855 ------TLKAIGDIELASKQGTLILAG--YGGQAGNGSEKVLNLTTTGGG------ISLE 900
T++A DI + G + AG G AGN N T G + E
Sbjct 2097 TATDGLTMRAGQDINVT---GANVSAGGSLGMAAGNDINITANEIVTSEGRAGRNRATTE 2153
Query 901 GASVELQGAQLNAEKNIKILANNE--------------NIQIISIKNKLNNSKLSDSNKL 946
ASV QG+ L+A ++ + A N+ IQ + L + + S+
Sbjct 2154 TASVTHQGSTLSAGDDLTLQAGNDVNARAAAIAAEGDVGIQAGRDVDLLAEASMERSSSQ 2213
Query 947 LVDLVEIDNKLKK--ISINNQYTELFLADVKILENAYDIAFNFNPS-AYKEDASYRKGSD 1003
ID +++ I + + LA + A D+ + A D + ++
Sbjct 2214 AKKKTAIDESVRQQGTEIASGGNTVILAGRDVTAQAADVTAQGDIGVAAGRDVNLTTATE 2273
Query 1004 KDIQFFNEVY--DGFV-KKYSDIIEPNIYSQQLNGTKYSTQISIAVP----------FGD 1050
D ++ + GF+ KK + IE +++ ++++ GD
Sbjct 2274 SDYRYREQTKTSSGFLSKKTTHTIEEESATREKGSLLSGDNVTVSAGNNLRVLGSAVAGD 2333
Query 1051 GDYARK-----EDILSPNGYFKYKYDQNK----------------IRSEINYLSQLNGYE 1089
GD A + + + N +++ + K +S + Q
Sbjct 2334 GDVALSAGNNVDIVAATNTDTAWRFKETKKSGLMGTGGIGFTIGSSKSTHDLREQGTTQS 2393
Query 1090 HFSSKLVSNSGSIDITSSKGISISGSELISKKGLVNIEALGALSQNYTSTIHGKDNKPKT 1149
S + S G++ I + K I G+++I++K +
Sbjct 2394 ESFSTVGSTGGNVSIAAGKQAHIGGADIIAQKDI------------------------SL 2429
Query 1150 LGASIIIDGSQDFYDKGNENDQKYRFRTILKPTLING--DKGVTIRATGNSNQDNLVLQA 1207
G S++I+ D + + +QK T+ + VT + + D+ +
Sbjct 2430 TGDSVVIEPGHDKRTRDEKFEQKSSGLTVALSGAAGSAVNNAVTTAQSAKQSSDSRLAAL 2489
Query 1208 TGITAANGDVRIEANKNILFDAAIEQSYDRSTTTEKKSSWGGLKKKYITTVSENNQANAA 1267
G AA V +A + + D S R+ T S+ G + ++ E+ +
Sbjct 2490 QGTQAALSGV--QAGQAVALDQVKGDSDKRNNNTIGVSASIGSQSSKSSSHMESETTTGS 2547
Query 1268 SVDISGKNIFIESKEKNPANNIDI-YSGKFIANGGQVSILSGGNINLYTVQESSSSNEDI 1326
++ +G N+ I+ A DI +G I G V++ + ++NL Q++ +
Sbjct 2548 TLS-AGNNVTIK------ATGSDITVAGSQIKAGKDVTLDAARDVNLIASQDTQQT---- 2596
Query 1327 TKKSSFSG-------------------IKYNTSKTNATRNQISELPGILKA-DYIGIKAD 1366
T K+S SG N+SK + N + + + A + + I
Sbjct 2597 TGKNSSSGGSLGVGVGVGSGGAGISISANANSSKGHEKGNGVWQNETTVDAGNRVTINTG 2656
Query 1367 NDVRLVGTEFEYLQAAKIQAGRNLSLLTASTTVTETLKKDKNSVVWQSMQDKGS------ 1420
D + G + + GR+L++ AST ++ +NSV + G+
Sbjct 2657 RDATIAGAQVSG-ETVVADIGRDLTI--ASTQDSDHYNSKQNSVSGGAGYTFGAGGFSGS 2713
Query 1421 --VTETAQLPRFNGPTPPEFKAAGGLIVQIPIGEKDQNKIEIRDQILILANQPGNEYLKQ 1478
V+ ++ AG + +G Q D +I + ++
Sbjct 2714 INVSRDKMTSDYDSVQEQSGLFAGNGGFDVTVGNHTQ-----LDSGVIASTATADK---- 2764
Query 1479 LVNRNDVDWQKVILAQKDWDYKSQGLTGAGAAIIAIIVVMVTAGAGSAVVGALGGSATTL 1538
NR D D+K++ GAG + I +A++ G S
Sbjct 2765 --NRLDTGTLGFSDIHNQADFKTEH-QGAGISSGGSIGKQFAGNMANALLAGGGNS---- 2817
Query 1539 GGSAVVMTQAAVT--SLATQASVSLINNGGDLGK-------TLKDLGSKDSVKNLAASVV 1589
G A TQAAV+ +L + + + DL + ++ + K+ + V
Sbjct 2818 -GHAEGTTQAAVSEGTLIIRDKENQKQDVADLSRDAEHANGSISPIFDKEKEQQRLQEVQ 2876
Query 1590 TAGLL-SQVGSALNLKPDTSGFSA---RLLNNFTTAVGS-------TLVQTAIK------ 1632
G + SQV N + + +G +A L + T G+ Q A++
Sbjct 2877 LIGEIGSQVVDIANTQGEINGLNAGRKELADKGITEPGADASDEVKAAYQNALRETDAYK 2936
Query 1633 --------GGDLEDNLKVA-----------LLAGLAGAMQGELASQIGTHLDKVDPNVFE 1673
G DL+ ++ A L A LAGA ELA +IG H +D N
Sbjct 2937 TTTAKYGTGSDLQRGIQAATAALQGLAGSDLTAALAGASAPELAYRIG-HGMGIDNNT-- 2993
Query 1674 YAIHKIAHAAVGCAVAAATKSSCEAGAIGAGVGEIVAS-----LMPDPVNGIEYNEDEKT 1728
A IAHA +G AVAA +S AGA GA GE+ A L PD + +E++K
Sbjct 2994 -AAKTIAHAILGGAVAALQGNSAAAGAAGAATGELAAKAIAGMLYPDVKDLSTLSEEQKQ 3052
Query 1729 KIRNTGKIVAGVVSAYAGYDVNTA---ANSADIAIQNNSLVKLA 1769
+ I AG+ AG +A + A +NNSL +A
Sbjct 3053 TVSALATISAGMAGGLAGDSTGSAVAGGQAGKNAAENNSLALVA 3096
Score = 72.8 bits (177), Expect = 6e-15
Identities = 179/853 (21%), Positives = 326/853 (38%), Gaps = 141/853 (17%)
Query 11 NQARQMFMAVAENVKSQTKTSGQSTASSVTVEQSQPFHQ--LWQVKCLVASMSLWMP--- 65
+Q R + + AE Q KT G ++T EQ + LW + ++ +P
Sbjct 1922 DQMRYLMDSAAE----QQKTLGLKFGVALTAEQVAALDKSMLWWESATINGQTVMIPKVY 1977
Query 66 LAPVYAQIQADNSANAGNRPVIGVGQNSQGQNVPVVN-IQTPTNGVSHNIYKQMDVLPEG 124
L+P + + + + N + G + G + N + ++ N+ +L G
Sbjct 1978 LSPKDVTVHSGSVISGNNVQLAGGNVINSGSTIAAQNGLSIDSSNSLSNL--NAGLLSAG 2035
Query 125 VVLNNSRTGANSSLVGTVGANPFLAKGEARIILNEVNSSVASRFEGNLEVAG-------- 176
LN S G +++ T+ + A I N + + GN+ +G
Sbjct 2036 GGLNLSALGDINNIGSTISGKTVGLESVAGSINNITRAQQWNVDAGNVHFSGTDVGKTAS 2095
Query 177 --------QRADVIIANPAGINIKGGGF----------INANKAILTTGKPQLNADGSIQ 218
RA I N G N+ GG I AN+ + + G+ N +
Sbjct 2096 ITATDGLTMRAGQDI-NVTGANVSAGGSLGMAAGNDINITANEIVTSEGRAGRNRATTET 2154
Query 219 QFVVDQGKITISANSGSSLGLGGNKNNADYVDLYARALELNAQLYANKDIQAITGANNIS 278
V QG T+SA +L G + N A A E + + A +D+ + A+
Sbjct 2155 ASVTHQGS-TLSAGDDLTLQAGNDVN----ARAAAIAAEGDVGIQAGRDVDLLAEAS--- 2206
Query 279 ADLQQISTRTGTGTTPTLAID--VKNLGGMYA---NNIYLLGNE---KGLGVSNAGTI-- 328
R+ + AID V+ G A N + L G + + V+ G I
Sbjct 2207 ------MERSSSQAKKKTAIDESVRQQGTEIASGGNTVILAGRDVTAQAADVTAQGDIGV 2260
Query 329 RAVNNLVVTSAGKIEHKGSLESTSNTQGLVSIQTTQT-GDNGNINSSGSITSKSMLSIDA 387
A ++ +T+A + +++ E T + G +S +TT T + GS+ S +++ A
Sbjct 2261 AAGRDVNLTTATESDYRYR-EQTKTSSGFLSKKTTHTIEEESATREKGSLLSGDNVTVSA 2319
Query 388 ANHLNITGNQVIVNQGVVSPLLLSAQGDI------NVSNGAIIKNVQTGGDIYLDAQNIN 441
N+L + G+ V + V LSA ++ N K + G +
Sbjct 2320 GNNLRVLGSAVAGDGDVA----LSAGNNVDIVAATNTDTAWRFKETKKSGLMGTGGIGFT 2375
Query 442 VG--------------ENTQIANVGLVNLNAAAAIDIKKSARVKAVNDLNIIAKQGLSVA 487
+G ++ + VG N + A + + + +IIA++ +S+
Sbjct 2376 IGSSKSTHDLREQGTTQSESFSTVGSTGGNVSIA-----AGKQAHIGGADIIAQKDISLT 2430
Query 488 DANLVAEKGNMNLQSNSNITLQGTTLDLTKDLNINGTGNVNLSSLNFSLLNGSSTLQNI- 546
++V E G+ + + + L + N +++ + + S L +
Sbjct 2431 GDSVVIEPGHDKRTRDEKFEQKSSGLTVALSGAAGSAVNNAVTTAQSAKQSSDSRLAALQ 2490
Query 547 NAYSGLNLVWDQTAKALPQISGNVTLEAANLIDLKGS--NLSGKGDLKLQGKALNVGADL 604
+ L+ V A AL Q+ G+ N I + S + S K ++ + G+ L
Sbjct 2491 GTQAALSGVQAGQAVALDQVKGDSDKRNNNTIGVSASIGSQSSKSSSHMESET-TTGSTL 2549
Query 605 TAGKSLNLTATQSDLIL---------NKTLNAQGNIDIASLDGKLNATGLNATSSQGKLS 655
+AG ++ + AT SD+ + + TL+A ++++ + TG N +SS G L
Sbjct 2550 SAGNNVTIKATGSDITVAGSQIKAGKDVTLDAARDVNLIASQDTQQTTGKN-SSSGGSLG 2608
Query 656 I------FGAKDTVLTNSGTVKTTLKGNQGV--NVGTISTGNLTLQNTVLESQNGAIVVT 707
+ GA ++ N+ + K KGN GV N T+ GN NT ++ T
Sbjct 2609 VGVGVGSGGAGISISANANSSKGHEKGN-GVWQNETTVDAGNRVTINTGRDA-------T 2660
Query 708 SEGQNTLTDSIITAKGNIELFAKDNLTLDGIKSSSQQHTALNSKKNI------YINSQAG 761
G ++++ G +LT+ +S+Q NSK+N Y G
Sbjct 2661 IAGAQVSGETVVADIGR-------DLTI----ASTQDSDHYNSKQNSVSGGAGYTFGAGG 2709
Query 762 TGDSVNFSSTKIT 774
S+N S K+T
Sbjct 2710 FSGSINVSRDKMT 2722
Score = 71.6 bits (174), Expect = 1e-14
Identities = 261/1235 (21%), Positives = 449/1235 (36%), Gaps = 239/1235 (19%)
Query 129 NSRTGANS-SLVGTVGANPFLAKGEARIILNEVNSSVASRFEGNLEVAGQRA-------- 179
N+R G + S G V LA G + +V + GN+ V+GQ A
Sbjct 274 NARQGDIALSSAGKVVLKNTLASGSTTVSAADVTLRGDHKAGGNVTVSGQTALTLDQAHV 333
Query 180 ----DVIIANPAGINIKGGGFINANKAIL--TTGKPQLNADGSIQQFVVDQGKITISANS 233
++ + + GG F AN A L TT ++A S + + + + N
Sbjct 334 AADNNLQLTTRGTLTQNGGAFTAANDATLAATTLIQSVDAQASAGRHLAVNAEKNAALNG 393
Query 234 GSSLGLGGNKNNADYV---DLYARALELNAQLYANKDIQAITGANNISADLQQISTRTGT 290
G + + V +L A + LNAQ + + NI+ S G+
Sbjct 394 SVVAGQQLSVKGGELVQQGNLSASEIALNAQTLTQESRSTTNASGNITLTTSGHSQLKGS 453
Query 291 GTT-PTLAIDVKNLGGMYANNIYLLGNEKGLGV-SNAGTIRA----VNNLVVTSAGKIEH 344
T +LA+ +L + + G+ SN GT++ V+ +TS+G ++
Sbjct 454 TTAGQSLAVSAGSLAN-HGALAAVADTRINTGIFSNTGTVQGNSLTVSGTDITSSGALKS 512
Query 345 KGSLESTSNTQGL-----VSIQTTQTGDNGNINSSGSITSKSMLSIDAANHLN---ITGN 396
+L+ ++ L +TT T +GN+N+SG++ S L+++AA +N ++G
Sbjct 513 ASTLDIRADNATLSGETGAKGKTTVTA-SGNLNNSGTLISDDTLTLNAAQIVNSGTLSGV 571
Query 397 QVIVNQGVV----SPLLLSAQGDINVSNG--AIIKNVQTGGDIYLDAQNINVGENTQI-- 448
+ + G + + + GD+ ++N + GG + + +++N Q
Sbjct 572 RGLTTSGKTFTASATSVTQSDGDVALNNTDTTLAGETSAGGAVTVQGRSLNTTATAQTQG 631
Query 449 --ANVGLVNLNAAAAIDIKKSARVKAVNDLNIIAKQ---GLSVADANLVAEKGNMNLQS- 502
V + N K + +KA + LN K GL V +L + G + +
Sbjct 632 NSVGVAVQNAKLEGTQAAKGNMTLKADSSLNHTGKSSASGLKVETGHL-SNSGTLTASAL 690
Query 503 --------NSNITLQGTTLDLTKDLNINGTGNVNLS----SLNFSLLNGS---------- 540
N + G TL L L N + V S SL+ S LN +
Sbjct 691 VIDSPEVINGGLIHAGQTLSLVTRLLDNRSSGVLYSPSALSLSLSELNNAGIITSDAALS 750
Query 541 ---STLQNINAYSGLNLVWD-QTAKALPQISGNVTLEAANLIDLKGSNLSGKGDLKLQGK 596
S L N SG +L D +T K + G + + AN I + + +G + G
Sbjct 751 LSGSNLTNSGELSGTSLAIDYETLKNSAE--GMLLAQGANRITAQSVSSAGS----MVGN 804
Query 597 ALNVGAD-------LTAGKSLNLTATQSDLILNK-------------TLNAQG-----NI 631
L + AD L +L+LTA +L+ TL G ++
Sbjct 805 TLTLNADRLESAGLLQGDSALSLTAGILNLLTGSRTLTGGALGLSGTTLTTAGQLQGQDV 864
Query 632 DIASLD----GKLNATGLNATSSQGKLSIFGAKDTVLTNSGTVK--TTLKGNQGVNVGTI 685
I S D G ATG ++ G LS G + + +GT+ TT+ ++ G +
Sbjct 865 SIRSHDWTNRGSSLATGSLDVTTAGTLSNTG--ELMSQGNGTLNAVTTVNSGNMLSAGDL 922
Query 686 STGNLTLQNTVLESQNGAIV----VTSEGQNT----------------LTDSIITAKGNI 725
S TL+N+ N +T+ G T L + A G++
Sbjct 923 SLNGKTLRNSGTLQGNRVTAHQDTITNSGTLTGIAALMLAARLEMAAPLLTLVNDASGSL 982
Query 726 ELFAKDNLTLDGIKSSSQQHTALNSKKNIYINSQAGT-GDSVNFSSTKITELNSTGTLSL 784
+ ++T ++++ Q K + I++QA T G ++ + +++ST T +
Sbjct 983 LTAGELSVTGGDLRNAGQWQG-----KRVLIHAQALTNGGAIQAENLLDAQIDSTLTGTA 1037
Query 785 ISDKNQNLQNTRLTGGAILLEAGGTLNTPKVIEFNAT-GSNLLKNDSKLNSLNGDLSIQT 843
S N G + L A N+ + I + T G++ L N ++ + T
Sbjct 1038 GSKITSN--------GELALSALTLANSGQWIAKHLTLGASTLNNSGEITGVVALSVALT 1089
Query 844 KESLTIDPNIHTLKAIG-DIELASKQG------TLILAGYGGQAGN--GSEKVLN----L 890
+ + + + A+ D+E A+ G T + AG +G G LN L
Sbjct 1090 QLNNQAGGKLLSAGALTLDVENATNAGQIQGKATTVTAGQLINSGRLQGEALTLNASGAL 1149
Query 891 TTTGGGISLEGASVELQGAQLNAEKNIKILANNENIQIISIKNKLNNSKLSDSNKLLVDL 950
T G+ L ++ + A LN N L + + N+ K+ KL +
Sbjct 1150 NNTASGVLLSENALTVSTATLN---NQGTLQGGGESSVKATTRVQNDGKMLSGGKLTLTA 1206
Query 951 VEIDNKLKKISINNQYTELFLADVKILENAYDIAFNFNPSAYKEDASYRKGSDKDIQFFN 1010
E+ N + Q L L VK + +A + +GS D
Sbjct 1207 PELANSSSGLV---QAVRLLLDVVKAVNGGNVLATT---------RAELRGSSLDNSGTL 1254
Query 1011 EVYDGFVKKYSDIIEPNIYSQQLNGTKYSTQISIAVPFGDGDYARKEDILSPNGYFKYKY 1070
+ D ++ N S +GT T L+ NG
Sbjct 1255 QGAD---------LQANYQSVTNSGTVLGTTS-----------------LTINGDALDNT 1288
Query 1071 DQNKIRSEINYLSQLNGYEHFSSKLVSNSGSIDITSSKGISISGSELISKKGLVNIEALG 1130
+ K+ S L + Y SG D+ +S+ + L LVN L
Sbjct 1289 ESGKLYSGDKLLLDVRNY----------SGRGDV-----VSLGDTTLKLVNALVNTGTLA 1333
Query 1131 ALSQNYTSTIHGKDNKPKTLGASIIIDGSQDFYDKGNENDQKYRFRTILKPTLINGDKGV 1190
A S+ + N G +I + F + G TL G+
Sbjct 1334 ASKTLSVSSQNAMTNSGVMQGNAIALSAGGAFTNNG---------------TLTTGNGSS 1378
Query 1191 TIRATGNSNQDNLVLQATGITAANGDVRIEANKNI 1225
T N +L+L A+G A GDV++ + +NI
Sbjct 1379 TF------NAQSLLLNASGSLQAGGDVQLTSRENI 1407
Score = 59.3 bits (142), Expect = 7e-11
Identities = 146/669 (22%), Positives = 258/669 (39%), Gaps = 112/669 (17%)
Query 183 IANPAGINIKGGGFINANKAI-----LTTGKPQLNA-----DGSIQQFVVDQGKITISAN 232
++N + +G G +NA + L+ G LN G++Q V + TI+ N
Sbjct 891 LSNTGELMSQGNGTLNAVTTVNSGNMLSAGDLSLNGKTLRNSGTLQGNRVTAHQDTIT-N 949
Query 233 SGSSLGLGGNKNNADYVDLYARALELNAQLYANKDIQAITGANNISADLQQISTRTGTGT 292
SG+ G+ + A LE+ A L +T N+ S L + TG
Sbjct 950 SGTLTGIAAL--------MLAARLEMAAPL--------LTLVNDASGSLLTAGELSVTGG 993
Query 293 TPTLAIDVKNLGGMYANNIYLLGNEKGLGVSNAGTIRAVN--------NLVVTSAGKIEH 344
D++N G + + ++N G I+A N L T+ KI
Sbjct 994 ------DLRNAGQWQGKRVLIHAQ----ALTNGGAIQAENLLDAQIDSTLTGTAGSKITS 1043
Query 345 KGSLESTSNTQGLVS--IQTTQTGDNGNINSSGSITSKSMLSIDAANHLNITGNQVIVNQ 402
G L ++ T I T +N+SG IT LS+ N G +
Sbjct 1044 NGELALSALTLANSGQWIAKHLTLGASTLNNSGEITGVVALSVALTQLNNQAGGK----- 1098
Query 403 GVVSPLLLSAQGDINVSNGAIIKNVQTGGDIYLDAQNINVGENTQIANVGLVNLNAAAAI 462
LLSA G + + ++N G I A + G Q+ N G + A+
Sbjct 1099 ------LLSA-GALTLD----VENATNAGQIQGKATTVTAG---QLINSGRLQ---GEAL 1141
Query 463 DIKKSARVKAVNDLNIIAKQGLSVADANLVAEKGNMNLQSNSNITLQGTTLDLTKDLNIN 522
+ S + ++++ L+V+ A L LQ +++ TT ++
Sbjct 1142 TLNASGALNNTASGVLLSENALTVSTATL---NNQGTLQGGGESSVKATTRVQNDGKMLS 1198
Query 523 GTGNVNLSSLNFSLLNGSSTLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANLIDLKG 582
G G + L++ L N SS L + L+ D KA+ GNV A +L+G
Sbjct 1199 G-GKLTLTAPE--LANSSSGL-----VQAVRLLLD-VVKAVN--GGNVL--ATTRAELRG 1245
Query 583 SNLSGKGDLKLQGKALNVGADLTAGKSLNLTA----------TQS------DLILNKTLN 626
S+L G L+ N + +G L T+ T+S D +L N
Sbjct 1246 SSLDNSGTLQGADLQANYQSVTNSGTVLGTTSLTINGDALDNTESGKLYSGDKLLLDVRN 1305
Query 627 AQGNIDIASLDGKLNATGLNATSSQGKLSIFGAKDTVLTNSGTVKTTLKGNQGVNVGTIS 686
G D+ SL G +NA + G L+ A T+ +S T QG N +S
Sbjct 1306 YSGRGDVVSL-GDTTLKLVNALVNTGTLA---ASKTLSVSSQNAMTNSGVMQG-NAIALS 1360
Query 687 TGNLTLQNTVLESQNGAIVVTSEGQNTLTDSIITAKGNIELFAKDNLTLDGIKSSSQQHT 746
G N L + NG+ ++ + A G+++L +++N+T++G ++ T
Sbjct 1361 AGGAFTNNGTLTTGNGSSTFNAQSLLLNASGSLQAGGDVQLTSRENITVNGFTGTAGSLT 1420
Query 747 ALNSKKNIYINSQAGTGDSVNFSSTKITELNSTGTLSLISDKNQNLQNTRL-TGGAILLE 805
+ + + + G++++ + +I + +++D + +Q + A ++
Sbjct 1421 -MTAAGTLLNTALIYAGNNISLFAARIHNIYG----DILADNSLWMQKNAVGEANAEVVN 1475
Query 806 AGGTLNTPK 814
GT+ T +
Sbjct 1476 RSGTIETTR 1484
Score = 42.7 bits (99), Expect = 8e-06
Identities = 67/354 (19%), Positives = 137/354 (39%), Gaps = 44/354 (12%)
Query 1091 FSSKLVSNSGSIDITSSKGISISGSELISKKGLVNIEALGALSQNYTSTIHGKDNKPKTL 1150
F ++ VSN+ ++ T S+ I+ GS+L + L++ A T+ K T
Sbjct 1896 FDTRYVSNA-ILNQTGSRYINGIGSDLDQMRYLMDSAA------EQQKTLGLKFGVALTA 1948
Query 1151 GASIIIDGSQDFYDKGNENDQKYRFRTILKPTLINGDKGVTIRATGNSNQDNLVLQATGI 1210
+D S +++ N Q T++ P + K VT+ + + +N+ Q G
Sbjct 1949 EQVAALDKSMLWWESATINGQ-----TVMIPKVYLSPKDVTVHSGSVISGNNV--QLAGG 2001
Query 1211 TAANGDVRIEANKNILFDAAIEQSYDRSTTTEKKSSWGGLKKKYITTVSE---------- 1260
N I A + D++ S + S+ GGL + ++
Sbjct 2002 NVINSGSTIAAQNGLSIDSSNSLS---NLNAGLLSAGGGLNLSALGDINNIGSTISGKTV 2058
Query 1261 ---------NNQANAASVDISGKNIFIESKEKNPANNIDIYSGKFIANGGQVSIL----- 1306
NN A ++ N+ + +I G + G +++
Sbjct 2059 GLESVAGSINNITRAQQWNVDAGNVHFSGTDVGKTASITATDGLTMRAGQDINVTGANVS 2118
Query 1307 SGGNINLYTVQESSSSNEDITKKSSFSGIKYNTSKTNATRNQISELPGILKADYIGIKAD 1366
+GG++ + + + + +I +G T++T + +Q S L D + ++A
Sbjct 2119 AGGSLGMAAGNDINITANEIVTSEGRAGRNRATTETASVTHQGSTLSA---GDDLTLQAG 2175
Query 1367 NDVRLVGTEFEYLQAAKIQAGRNLSLLTASTTVTETLKKDKNSVVWQSMQDKGS 1420
NDV IQAGR++ LL ++ + + K + + +S++ +G+
Sbjct 2176 NDVNARAAAIAAEGDVGIQAGRDVDLLAEASMERSSSQAKKKTAIDESVRQQGT 2229
Score = 39.7 bits (91), Expect = 7e-05
Identities = 116/565 (21%), Positives = 207/565 (37%), Gaps = 61/565 (11%)
Query 1092 SSKLVSNSGSIDITSS-----KGISISGSEL-ISKKGLVNIEALGALSQNYTSTIHGKDN 1145
S + SG+I +T+S KG + +G L +S L N AL A++ +T G +
Sbjct 430 SRSTTNASGNITLTTSGHSQLKGSTTAGQSLAVSAGSLANHGALAAVADTRINT--GIFS 487
Query 1146 KPKTL-GASIIIDGSQDFYDKGNENDQKYRFRTILKPTLINGDKGV----TIRATGNSNQ 1200
T+ G S+ + G+ ++ R ++G+ G T+ A+GN N
Sbjct 488 NTGTVQGNSLTVSGTDITSSGALKSASTLDIRA--DNATLSGETGAKGKTTVTASGNLNN 545
Query 1201 DNLVLQATGITAANGDVRIEANKNILFDAAIEQSYDRSTTTEKKSSWGGLKKKYITTVSE 1260
++ +T + + + ++ T S G + T
Sbjct 546 SGTLISDDTLTLNAAQIVNSGTLSGVRGLTTSGKTFTASATSVTQSDGDVALNNTDTTLA 605
Query 1261 NNQANAASVDISGKNIFIESKEKNPANNIDIYSGKFIANGGQVSILSGGNINLYTVQESS 1320
+ +V + G+++ + + N++ + G Q + GN+ T++ S
Sbjct 606 GETSAGGAVTVQGRSLNTTATAQTQGNSVGVAVQNAKLEGTQAA---KGNM---TLKADS 659
Query 1321 SSNEDITKKSSFSGIKYNTSKTNATRNQISELPGILKADYIGIKADNDVRLVGTEFEYLQ 1380
S N T KSS SG+K T + + G L A + I + E +
Sbjct 660 SLNH--TGKSSASGLKVETGHLSNS--------GTLTASALVIDSP----------EVIN 699
Query 1381 AAKIQAGRNLSLLTA---STTVTETLKKDKNSVVWQSMQDKGSVTETAQLPRFNGPTPPE 1437
I AG+ LSL+T + + S+ + + G +T A L +G
Sbjct 700 GGLIHAGQTLSLVTRLLDNRSSGVLYSPSALSLSLSELNNAGIITSDAALS-LSGSNLTN 758
Query 1438 FKAAGGLIVQIPIGEKDQNKIEIRDQILILANQPGNEYLKQLVNRNDVDWQKVILAQKDW 1497
G + I D ++ + ++LA Q N Q V+ + D
Sbjct 759 SGELSGTSLAI-----DYETLKNSAEGMLLA-QGANRITAQSVSSAGSMVGNTLTLNADR 812
Query 1498 DYKSQGLTGAGAAIIAIIVVMVTAGAGSAVVGALGGSATTL-------GGSAVVMTQAAV 1550
+ L G A + ++ + G+ + GALG S TTL G + +
Sbjct 813 LESAGLLQGDSALSLTAGILNLLTGSRTLTGGALGLSGTTLTTAGQLQGQDVSIRSHDWT 872
Query 1551 TSLATQASVSL-INNGGDLGKTLKDLGSKDSVKNLAASVVTAGLLSQVGSALNLKPDTSG 1609
++ A+ SL + G L T + + + N +V + +LS +LN K T
Sbjct 873 NRGSSLATGSLDVTTAGTLSNTGELMSQGNGTLNAVTTVNSGNMLSAGDLSLNGK--TLR 930
Query 1610 FSARLLNNFTTAVGSTLVQTAIKGG 1634
S L N TA T+ + G
Sbjct 931 NSGTLQGNRVTAHQDTITNSGTLTG 955
Score = 37.4 bits (85), Expect = 3e-04
Identities = 158/823 (19%), Positives = 295/823 (36%), Gaps = 128/823 (16%)
Query 1158 GSQDFYDK-GNENDQKYRFRTILKPTLINGDKGVTIRATGNSNQDNLVLQATGITAANGD 1216
GS F D+ G D+ YRF GD R N+ +L TG NG
Sbjct 1872 GSSYFLDRLGLNPDRDYRFL---------GDAAFDTRYVSNA-----ILNQTGSRYINGI 1917
Query 1217 VRIEANKNILFDAAIEQ------------------SYDRSTTTEKKSSWGG----LKKKY 1254
L D+A EQ + D+S + ++ G + K Y
Sbjct 1918 GSDLDQMRYLMDSAAEQQKTLGLKFGVALTAEQVAALDKSMLWWESATINGQTVMIPKVY 1977
Query 1255 IT----TVSENNQANAASVDISGKNIFIESKEKNPANNIDIYSGKFIANGGQVSILSGGN 1310
++ TV + + +V ++G N+ N + I S ++N + +GG
Sbjct 1978 LSPKDVTVHSGSVISGNNVQLAGGNVINSGSTIAAQNGLSIDSSNSLSNLNAGLLSAGGG 2037
Query 1311 INLYTVQESSSSNEDITKKS----SFSGIKYNTSK----------TNATRNQISELPGIL 1356
+NL + + ++ I+ K+ S +G N ++ + + + + I
Sbjct 2038 LNLSALGDINNIGSTISGKTVGLESVAGSINNITRAQQWNVDAGNVHFSGTDVGKTASIT 2097
Query 1357 KADYIGIKADNDVRLVGTEFEYLQAAKIQAGRNLSLLTASTTVTETLKKDKNSVVWQSMQ 1416
D + ++A D+ + G + + AG +++ +TA+ VT + +N
Sbjct 2098 ATDGLTMRAGQDINVTGANVSAGGSLGMAAGNDIN-ITANEIVTSEGRAGRNR------- 2149
Query 1417 DKGSVTETAQLPRFNGPTPPEFKAAGGLIVQIPIGEKDQN----KIEIRDQILILANQPG 1472
+ TETA + G T A L +Q D N I + I A +
Sbjct 2150 ---ATTETASVTH-QGST---LSAGDDLTLQ---AGNDVNARAAAIAAEGDVGIQAGRDV 2199
Query 1473 NEYLKQLVNRNDVDWQKVILAQKDWDYKSQGLTGAGAAIIAIIVVMVTAGAGSAVVGALG 1532
+ + + R+ +K + + + G +I + A G +G
Sbjct 2200 DLLAEASMERSSSQAKKKTAIDESVRQQGTEIASGGNTVILAGRDVTAQAADVTAQGDIG 2259
Query 1533 GSATTLGGSAVVMTQAAVTSLATQASVSLINNGGDLGKTLKDLGSKDSVKNLAASVVTAG 1592
+A G V +T A + + + G L K ++S S+++
Sbjct 2260 VAA----GRDVNLTTATESDYRYREQTK--TSSGFLSKKTTHTIEEESATREKGSLLSGD 2313
Query 1593 LLSQVGSALNLKPDTSGFSARLLNNFTTAVGSTLVQTAIKGGDLEDNLKVALLAGL--AG 1650
++ V + NL+ G + + + G+ + A D K +GL G
Sbjct 2314 NVT-VSAGNNLR--VLGSAVAGDGDVALSAGNNVDIVAATNTDTAWRFKETKKSGLMGTG 2370
Query 1651 AMQGELASQIGTHLDKVDPNVFEYAIHKIAHAAVGCAVAAATKSSCEAGAIGAGVGEIVA 1710
+ + S TH + + + ++AA ++ I + +
Sbjct 2371 GIGFTIGSSKSTHDLREQGTTQSESFSTVGSTGGNVSIAAGKQAHIGGADI---IAQKDI 2427
Query 1711 SLMPDPV----NGIEYNEDEKTKIRNTGKIVAGVVSAYAGYDVNTAANSADIAIQNNSLV 1766
SL D V + DEK + +++G VA +S AG VN A +A A Q++
Sbjct 2428 SLTGDSVVIEPGHDKRTRDEKFEQKSSGLTVA--LSGAAGSAVNNAVTTAQSAKQSSD-S 2484
Query 1767 KLATSTGKILVKTLDEFNALRKAGKQVTKDDLVTSFKKQGADELIGIADDLLTVFGRSSS 1826
+LA G T + + +AG+ V D + K+ + IG++ + + +SSS
Sbjct 2485 RLAALQG-----TQAALSGV-QAGQAVALDQVKGDSDKRN-NNTIGVSASIGSQSSKSSS 2537
Query 1827 SFDRALAAIDLIVGTDLKPGKGESLKIAKNELEKLKTDRSYVQTVYQNKIDVITRNRLNG 1886
+ + G+ L G ++K +++ TV ++I G
Sbjct 2538 HMES-----ETTTGSTLSAGNNVTIKATGSDI-----------TVAGSQIKA-------G 2574
Query 1887 KEFETSAASKLGIQRNTDRQMITVKTERDGQINIIPDAFGNGG 1929
K+ AA + + + D Q T K G + G+GG
Sbjct 2575 KDVTLDAARDVNLIASQDTQQTTGKNSSSGGSLGVGVGVGSGG 2617
Score = 33.1 bits (74), Expect = 0.006
Identities = 145/743 (20%), Positives = 257/743 (35%), Gaps = 112/743 (15%)
Query 132 TGANSSLVGTVGANPFLAKGEARIILNEVNSSVASRFEGN-------LEVAGQRADVIIA 184
TG NSS G++G + G A I ++ +S +GN AG R +
Sbjct 2597 TGKNSSSGGSLGVGVGVGSGGAGISISANANSSKGHEKGNGVWQNETTVDAGNRVTINTG 2656
Query 185 NPAGINIKGGGFINANKAILTTGKPQLNADGSIQQFVVDQGKITISANSGSSLGLGG--- 241
A I G ++ + G+ L + + + ++S +G + G GG
Sbjct 2657 RDATI---AGAQVSGETVVADIGR-DLTIASTQDSDHYNSKQNSVSGGAGYTFGAGGFSG 2712
Query 242 ------NKNNADYVDLYARALELNAQLYANKDIQAITGANNISADLQQISTRTGTGTTPT 295
+K +DY +++ + L+A +T N+ D I++ T T
Sbjct 2713 SINVSRDKMTSDY-----DSVQEQSGLFAGNGGFDVTVGNHTQLDSGVIAS---TATADK 2764
Query 296 LAIDVKNLGGMYANNIYLLGNE-KGLGVSNAGTIRA-----VNNLVVTSAGKIEHKGSLE 349
+D LG +N E +G G+S+ G+I + N ++ G H
Sbjct 2765 NRLDTGTLGFSDIHNQADFKTEHQGAGISSGGSIGKQFAGNMANALLAGGGNSGHAEGTT 2824
Query 350 STSNTQGLVSIQT--TQTGDNGNIN-----SSGSIT-----SKSMLSIDAANHLNITGNQ 397
+ ++G + I+ Q D +++ ++GSI+ K + + G+Q
Sbjct 2825 QAAVSEGTLIIRDKENQKQDVADLSRDAEHANGSISPIFDKEKEQQRLQEVQLIGEIGSQ 2884
Query 398 VIV---NQGVVSPL-----------LLSAQGDINVSNGAIIKNVQTGGDIY-LDAQNINV 442
V+ QG ++ L + D + A +N D Y
Sbjct 2885 VVDIANTQGEINGLNAGRKELADKGITEPGADASDEVKAAYQNALRETDAYKTTTAKYGT 2944
Query 443 GENTQIA-NVGLVNLNAAAAIDIKKSARVKAVNDLNIIAKQGLSVADANLVAEKGNMNLQ 501
G + Q L A D+ + + +L G+ + D N A+ +
Sbjct 2945 GSDLQRGIQAATAALQGLAGSDLTAALAGASAPELAYRIGHGMGI-DNNTAAKTIAHAIL 3003
Query 502 SNSNITLQGTTLDL------TKDLNINGTGNV------NLSSLNFSLLNGSSTLQNINAY 549
+ LQG + T +L + +LS+L+ S L I+A
Sbjct 3004 GGAVAALQGNSAAAGAAGAATGELAAKAIAGMLYPDVKDLSTLSEEQKQTVSALATISAG 3063
Query 550 SGLNLVWDQTAKALP--QISGNVTLEAANLIDLKGSNLSGKGDLKLQGKALNVGADL--- 604
L D T A+ Q N + + +G ++ K+ + L +GA
Sbjct 3064 MAGGLAGDSTGSAVAGGQAGKNAAENNSLALVARGCAVAAPCRTKVAEQLLEIGAKAGIA 3123
Query 605 ----TAGKSLNLTATQSDLILNKTLNAQGNIDIASLDGKLNATGLNATSSQGKLSIFGAK 660
A K + T +L TL GN +I + L + + G L
Sbjct 3124 GLAGAAVKDMADKMTSDELEHLVTLEMMGNDEIIAKYVSLLHDKYAPSHTGGNL------ 3177
Query 661 DTVLTNSGTVKTTLKGNQGVNVGTISTGNLTLQNTVLESQNGAIVV--TSEGQNTLTDSI 718
+ TL G+ G N G++ TG NT ++ +G+ T NT ++
Sbjct 3178 ---------LPETLPGHTGNNTGSVDTGPNHTGNTNRQNDSGSNNTGNTEGAPNTGGNTT 3228
Query 719 ITAKGNIELFAKDNLTLDGIKSSSQQHTALN---------SKKNIYINSQAGTGDSVNFS 769
IT N +KD++ +K Q A N K + Q D N+
Sbjct 3229 ITPIPNGP--SKDDIAYLALKGKEAQEAASNLGFDRRIPPQKAPFNSHGQPVFYDGKNYI 3286
Query 770 STKITELNSTGTLSLISDKNQNL 792
+ I N T + + K + +
Sbjct 3287 TPDIDSHNVTNGWKMFNSKGKRI 3309
Score = 26.6 bits (57), Expect = 0.61
Identities = 43/205 (21%), Positives = 77/205 (38%), Gaps = 23/205 (11%)
Query 1184 INGDKGVTIRATGNSNQDNLVLQATGITAANGDVRIEANKNILFDAAIEQSYDR------ 1237
++G +T+ + +NL L G NG AN L + QS D
Sbjct 320 VSGQTALTLDQAHVAADNNLQLTTRGTLTQNGGAFTAANDATLAATTLIQSVDAQASAGR 379
Query 1238 --STTTEKKSSWGG-------LKKKYITTVSENNQANAASVDISGKNIFIESKE-KNPAN 1287
+ EK ++ G L K V + N +A+ + ++ + + ES+ N +
Sbjct 380 HLAVNAEKNAALNGSVVAGQQLSVKGGELVQQGN-LSASEIALNAQTLTQESRSTTNASG 438
Query 1288 NIDIYSG-----KFIANGGQVSILSGGNINLYTVQESSSSNEDITKKSSFSGIKYNTSKT 1342
NI + + K GQ +S G++ + + + T S +G S T
Sbjct 439 NITLTTSGHSQLKGSTTAGQSLAVSAGSLANHGALAAVADTRINTGIFSNTGTVQGNSLT 498
Query 1343 NATRNQISELPGILKADYIGIKADN 1367
+ I+ + A + I+ADN
Sbjct 499 -VSGTDITSSGALKSASTLDIRADN 522
Score = 23.1 bits (48), Expect = 6.9
Identities = 38/164 (23%), Positives = 53/164 (32%), Gaps = 27/164 (16%)
Query 1586 ASVVTAGLLSQVGSALNLKPDTSGFSARLLNNFTTAVGSTLVQTAIKGGDLEDNLKVALL 1645
A+ G L+ A L PD S T + + GG D+ A+
Sbjct 3019 AAGAATGELAAKAIAGMLYPDVKDLSTLSEEQKQTVSALATISAGMAGGLAGDSTGSAVA 3078
Query 1646 AGLAGAMQGELASQIGTHLDKVDPNVFEYAIHKIAHAAVGCAVAAATKSS-----CEAGA 1700
G AG E S +A A GCAVAA ++ E GA
Sbjct 3079 GGQAGKNAAENNS--------------------LALVARGCAVAAPCRTKVAEQLLEIGA 3118
Query 1701 IG--AGVGEIVASLMPDPVNGIEYNEDEKTKIRNTGKIVAGVVS 1742
AG+ M D + E ++ +I+A VS
Sbjct 3119 KAGIAGLAGAAVKDMADKMTSDELEHLVTLEMMGNDEIIAKYVS 3162
>A0A1S4NYE3 tRNA nuclease CdiA [Escherichia coli (strain STEC_O31)]
Length=3253
Score = 236 bits (602), Expect = 1e-64
Identities = 355/1433 (25%), Positives = 580/1433 (40%), Gaps = 237/1433 (17%)
Query 85 PVIGVGQNSQGQNVPVVNIQTPTN-GVSHNIYKQMDVLPEGVVLNNSRTGAN-SSLVGTV 142
P G G + VPVVNI TP G+SHN + +V EG++LNN+ N + L G +
Sbjct 36 PQNGAGMDKAANGVPVVNIATPNGAGISHNRFTDYNVGKEGLILNNATGKLNPTQLGGLI 95
Query 143 GANPFL-AKGEARIILNEVNSSVASRFEGNLEVAGQRADVIIANPAGINIKGGGFINANK 201
NP L A GEA+ I+NEV S +G EVAG+ A+V++ANP GI G GFIN +
Sbjct 96 QNNPNLKAGGEAKGIINEVTGGNRSLLQGYTEVAGKAANVMVANPYGITCDGCGFINTPR 155
Query 202 AILTTGKPQLNADGSIQQFVVDQGKITISANSGSSLGLGGNKNNADYVDLYARALELNAQ 261
A LTTG+P +NADGS+Q V +G ITI+ G G + +D V + ARA E+NA
Sbjct 156 ATLTTGRPVMNADGSLQALEVTEGSITIN-------GAGLDGTRSDAVSIIARATEVNAA 208
Query 262 LYANKDIQAITGANNISADLQQISTRTGTGTTPTLAIDVKNLGGMYANNIYLLGNEKGLG 321
L+A KD+ GAN ++AD ++S G G P +A+D LGGMYA I+L E G+G
Sbjct 209 LHA-KDLTVTAGANRVTAD-GRVSALKGEGDVPKVAVDTGALGGMYARRIHLTSTESGVG 266
Query 322 VSNAGTIRAVNNLVVTSAGKIEHKGSLESTSNTQGLVSIQTTQTGDNGNINSSGSITSKS 381
V+ +++++S+GK+ K SL + TT TG +++ SG +
Sbjct 267 VNLGNLYAREGDIILSSSGKLVLKNSLAGGN---------TTVTGT--DVSLSGDNKAGG 315
Query 382 MLSIDAANHLNITGNQVIVNQGVVSPLLLSAQGDINVSNGAIIKNVQTGGDIYLDAQNIN 441
LS+ L + ++++ ++ L+LS+ G I V NG + G + L AQ++N
Sbjct 316 NLSVTGTTGLTLNQSRLVTDKN----LVLSSSGQI-VQNGG---ELTAGQNAMLSAQHLN 367
Query 442 VGENTQIANVGLVNLNAAAAIDIKKSARVKAVNDLNIIAKQGLSVADANLVAEKGNMNLQ 501
+NAA + + + I +G SVA L G++N
Sbjct 368 QTSGA---------VNAAENVTLTTTGG---------ITLKGRSVAGKTLTVSSGSLN-- 407
Query 502 SNSNITLQGTTLDLTKDLNINGTGNVNLSSLNFSLLNGSSTLQNINAYSGLNLVWDQTAK 561
G TL +D + + T N A G L T
Sbjct 408 -------NGGTLGAGRDATVK-----------------TGTFSNTGAVQGNGLKVTAT-- 441
Query 562 ALPQISGNVTLEAANLIDLKGSNLSGKGDLKLQGKA-------LNVGADLTAGKSLNLTA 614
++ ++++ + +D+ N + GD + A L L + L L+A
Sbjct 442 ---DLTSTGSIKSGSTLDISARNATLSGDAGAKDSARVTVSGTLENRGRLVSDDVLTLSA 498
Query 615 TQSDLILNKTLNAQGNIDIASLDGKLNATGLNATSSQGKLSIFGAKDTV---LTNSGTVK 671
TQ +N + G ++ + L T + T+S G L + A T+ + GTV
Sbjct 499 TQ----INNSGTLSGAKELVASADTLTTTEKSVTNSDGNLMLNSASSTLAGETSAGGTV- 553
Query 672 TTLKGNQGVNVGTIST-GN---LTLQNTVLE-SQNGAIVVTSEGQNTLTDSIITAKGNIE 726
++KGN T T GN + +QN L+ +Q ++T LT S ++ ++
Sbjct 554 -SVKGNSLKTTTTAQTQGNSVSVDVQNAQLDGTQAARDILTLNASEKLTHSGKSSAPSLS 612
Query 727 LFAKDNLTLDGIKSSSQQHTALNSKKNIYINSQAGTGDSVNFSSTKITELNSTGTLSLIS 786
L A + LT G+ +S ALN++ NS G++ +T+ + GTL +
Sbjct 613 LSAPE-LTSSGVLVAS----ALNTQSQTLTNSGLLQGEASLTVNTQRLDNQQNGTLYSAA 667
Query 787 DKNQNLQNTRLTGGAILLEAGGTLNTPKV----------IEFNAT---GSNLLKNDSKL- 832
D ++ + R G I + G TLNT + + AT G LL+ + L
Sbjct 668 DLTLDIPDIR-NSGLITGDNGLTLNTASLSNPGKITADTLNVRATTLDGDGLLQGAAALA 726
Query 833 ---NSLN----------GDLSIQTK----------ESLTID----PNIHTLKAIGDIELA 865
++L+ GDLS++ K ++LT+ N ++ A G++ A
Sbjct 727 LAGDTLSQGSHGRWLTAGDLSLRGKTLNTAGTTQGQNLTVQADRWANSGSVLATGNL-TA 785
Query 866 SKQGTLILAGYGGQAGNGSEKVLNLTTT--------GGGISLEGASVELQGA-------- 909
S G L G + + LN TT G +SL+G S++ G
Sbjct 786 SATGQLTST---GDIMSQGDTTLNAATTDNRGSLLSAGTLSLDGNSLDNSGTVQGNHVTL 842
Query 910 QLNAEKNIKILANNENIQIISIKNKLNNSKLSDSNKLLVDLVEIDNKLKKISINNQYTEL 969
+ N + + + S N+ L N L++ ++ N + N
Sbjct 843 HHRSTDNSGTVTGLSGLTLHSADGLTNSGALLSQNSLVLSAGDVTNSGRIQGQNITLDAS 902
Query 970 FLADVKILENAYDIAFNFNPSAYKEDASYRKGSDKDIQFFNEVYDGFVKKYSDIIEPNIY 1029
L +++A D+A + S + + D + +V + +E N
Sbjct 903 SLTSSGAVQSALDLALTLSGDVIAATGS-KITALGDARLTGKVLGNQGLISAKTLEVNGD 961
Query 1030 SQQLNGTKYSTQISIAVPFGDGDYARKEDILSPNGYFKYKYDQNKIRSEINYLSQLNGYE 1089
S N + S S+ V L +G N +I+ QL G +
Sbjct 962 SLS-NSGEISGVNSLNVTLSGN--------LQQHGKMLTGGALNVNARDISNSGQLQGAD 1012
Query 1090 H-FSSKLVSNSGSIDITSSKGISISGSELISKKGLV---NIEALGALSQNYTSTIHGKDN 1145
+ ++ ++NSG + S +++ + G++ N+ AL A TI G N
Sbjct 1013 NRITASSLANSGRVQGESGLTLTLLNALTNQTSGVLLSQNVSALSAPVLTNDGTIQG--N 1070
Query 1146 KPKTLGASIIIDGSQDFYDKGNENDQKYRFRTILKPTLINGDKGVTIRATGNSNQDNLVL 1205
TL A+ S G T P +G +L+L
Sbjct 1071 GKTTLSAATQAHNSGKILSGGE--------LTFTTP---------DYSGSGWLQATDLLL 1113
Query 1206 QATGITAANGDVRIEANK-----NILFDAAIEQSYDRSTTTEKKSSWGGLKKKYITTVSE 1260
+ A NG V + AN+ N L + + Q+ + T+ ++ G L T+
Sbjct 1114 NVAKL-AGNGTV-MAANQATLTGNSLTNRGLFQAAQLNVNTQTITNSGTLLGNQGLTIKG 1171
Query 1261 NNQANAASVDISGKNIFIESKEKNPANNIDIYSGKFIANGGQVSILSGG----NINLYTV 1316
NN NA SG ++ E + A G+ +A G L+ G +
Sbjct 1172 NNLNNAGGKVFSGGDMLAEMVSLSGA-------GQLVALGNLTLKLTRGLTAQGVIAANK 1224
Query 1317 QESSSSNEDITKKSSF--SGIKYNTSKTNATRNQISELPGILKADYIGIKADNDVRLVGT 1374
Q S SS DIT ++ +GI N + Q++ + L G+
Sbjct 1225 QLSVSSQGDITNGATLQGNGITLNAAGRLTNNGQLT-------------AGNGTTALSGS 1271
Query 1375 EFEYLQAAKIQAGRNLSLLTASTTVTETLKKDKNSVVWQSMQDKGSVTETAQL 1427
+ +QAG ++SL + + S++ + G+V TA L
Sbjct 1272 GIAMNASGSLQAGGDVSLTSRGDITLDAFTGTTGSLM---LTAAGAVINTALL 1321
Score = 103 bits (256), Expect = 4e-24
Identities = 205/914 (22%), Positives = 353/914 (39%), Gaps = 169/914 (18%)
Query 145 NPFLAKGEARIILN------EVNSSVASRFEGNLEVAGQRADVIIANPAGINIKGGGFIN 198
N L +GEA + +N + N ++ S + L++ R +I G+ + N
Sbjct 638 NSGLLQGEASLTVNTQRLDNQQNGTLYSAADLTLDIPDIRNSGLITGDNGLTLNTASLSN 697
Query 199 ANKAI---LTTGKPQLNADGSIQQFVVDQGKITISANSGSSLGLGGNKNNADYVDLYARA 255
K L L+ DG +Q G + A +G +L G + DL R
Sbjct 698 PGKITADTLNVRATTLDGDGLLQ------GAAAL-ALAGDTLSQGSHGRWLTAGDLSLRG 750
Query 256 LELN-------------AQLYANKDIQAITGANNISADLQQIST---------------- 286
LN A +AN TG SA Q ST
Sbjct 751 KTLNTAGTTQGQNLTVQADRWANSGSVLATGNLTASATGQLTSTGDIMSQGDTTLNAATT 810
Query 287 --RTGTGTTPTLAID---VKNLGGMYANNIYL-------LGNEKGL---------GVSNA 325
R + TL++D + N G + N++ L G GL G++N+
Sbjct 811 DNRGSLLSAGTLSLDGNSLDNSGTVQGNHVTLHHRSTDNSGTVTGLSGLTLHSADGLTNS 870
Query 326 GTIRAVNNLVVTSAGKIEHKGSLES---TSNTQGLVSIQTTQTGDNGNINSSGSITSKSM 382
G + + N+LV+ SAG + + G ++ T + L S Q+ + + SG + + +
Sbjct 871 GALLSQNSLVL-SAGDVTNSGRIQGQNITLDASSLTSSGAVQSALDLALTLSGDVIAATG 929
Query 383 LSIDAANHLNITGNQVIVNQGVVSPLLLSAQGD----------INVSNGAIIKNVQ---- 428
I A +TG +V+ NQG++S L GD +N N + N+Q
Sbjct 930 SKITALGDARLTG-KVLGNQGLISAKTLEVNGDSLSNSGEISGVNSLNVTLSGNLQQHGK 988
Query 429 --TGGDIYLDAQNINVGENTQIANVGLVNLNAAAAIDIKKSARVKAVNDLNIIAKQGLSV 486
TGG + ++A++I+ Q A+ N A + S RV+ + GL++
Sbjct 989 MLTGGALNVNARDISNSGQLQGAD------NRITASSLANSGRVQG--------ESGLTL 1034
Query 487 ADANLVAEKGNMNLQSNSNITLQGTTLDLTKDLNINGTGNVNLSSLNFS-----LLNGSS 541
N + + + L S + L L T D I G G LS+ + +L+G
Sbjct 1035 TLLNALTNQTSGVLLSQNVSALSAPVL--TNDGTIQGNGKTTLSAATQAHNSGKILSGGE 1092
Query 542 TLQNINAYSGLNLVWDQTAKAL---PQISGNVTLEAANLIDLKGSNLSGKGDLKLQGKAL 598
YSG W Q L +++GN T+ AAN L G++L+ +G Q L
Sbjct 1093 LTFTTPDYSGSG--WLQATDLLLNVAKLAGNGTVMAANQATLTGNSLTNRG--LFQAAQL 1148
Query 599 NVGADLTAGKSLNLTATQSDLIL-NKTLNAQGNIDIASLDGKLNATG-----LNATSSQG 652
NV T T S +L N+ L +GN ++ + GK+ + G + + S G
Sbjct 1149 NVNTQ---------TITNSGTLLGNQGLTIKGN-NLNNAGGKVFSGGDMLAEMVSLSGAG 1198
Query 653 KLSIFGAKDTVLTNSGTVKTTLKGNQGVNVGTIS--TGNLTLQNTVLESQNGAIVVTSEG 710
+L G LT T + + N+ ++V + T TLQ + + N A +T+ G
Sbjct 1199 QLVALGNLTLKLTRGLTAQGVIAANKQLSVSSQGDITNGATLQGNGI-TLNAAGRLTNNG 1257
Query 711 QNTLTDSIITAKGN-IELFAKDNLTLDGIKSSSQQHTALNSKKNIYINSQAGTGDSVNFS 769
Q T + G+ I + A +L G +L S+ +I +++ GT S+ +
Sbjct 1258 QLTAGNGTTALSGSGIAMNASGSLQAGG-------DVSLTSRGDITLDAFTGTTGSLMLT 1310
Query 770 ST----KITELNSTGTLSLISDKNQNLQNTRLTGGAILLEAGGTLNTPKVIEFNATGSNL 825
+ L + LSL + +N L G +++++ + A + +
Sbjct 1311 AAGAVINTALLYAGNNLSLFASTIRNHHGDMLAGDSLVMQKDVS---------GAANAEV 1361
Query 826 LKNDSKLNSLNGDLSIQTKESLTIDPNIHTLKAIGDIELAS----KQGTLILAGYGGQAG 881
+ + + GD++I+T L I+ K+ +E + + G G+ G
Sbjct 1362 INTSGNIETTRGDITIRTGHLLNQREGINETKSYIPVENVAVPDGANSVSVRVGDLGEDG 1421
Query 882 NGSEKVLNLTTTGGGISLEGASVELQGAQLNAEKNIKILANNENIQIISIKNKLNNSKLS 941
G T GGG E + K L + + + ++++S
Sbjct 1422 WGYYVKSWSGTAGGGFDAWAVPTEKGATR-------KFLTGTTRVDVGATGG---DARIS 1471
Query 942 DSNKLLVDLVEIDN 955
N LL+D ++DN
Sbjct 1472 AGNNLLIDADKLDN 1485
Score = 87.8 bits (216), Expect = 2e-19
Identities = 281/1345 (21%), Positives = 500/1345 (37%), Gaps = 242/1345 (18%)
Query 125 VVLNNSRTGANSSLVGTVGANPFLAKGEARIILNEVNSSVASRFEGNLEVAGQRADVI-- 182
+VL NS G N+++ GT +V+ S ++ GNL V G +
Sbjct 287 LVLKNSLAGGNTTVTGT-----------------DVSLSGDNKAGGNLSVTGTTGLTLNQ 329
Query 183 --IANPAGINIKGGGFINANKAILTTGKPQLNADGSIQQFVVDQGKITISAN----SGSS 236
+ + + G I N LT G+ NA S Q G + + N +
Sbjct 330 SRLVTDKNLVLSSSGQIVQNGGELTAGQ---NAMLSAQHLNQTSGAVNAAENVTLTTTGG 386
Query 237 LGLGGNKNNADYVDLYARALELNAQLYANKDIQAITGANNISADLQQISTR-TGTGTTPT 295
+ L G + + + +L L A +D TG + + +Q + T T T T
Sbjct 387 ITLKGRSVAGKTLTVSSGSLNNGGTLGAGRDATVKTGTFSNTGAVQGNGLKVTATDLTST 446
Query 296 LAIDVKNLGGMYANNIYLLGNEKGLGVSNAGTIRAVNNLVVTSAGKIEHKGSLESTSNTQ 355
+I + + A N L G+ AG A ++ VT +G +E++G L S
Sbjct 447 GSIKSGSTLDISARNATLSGD--------AG---AKDSARVTVSGTLENRGRLVSDD--- 492
Query 356 GLVSIQTTQTGDNGNINSSGS-ITSKSMLSIDAANHLNITGNQVIVNQGVVSPLLLSAQG 414
++++ TQ ++G ++ + + S L+ + N GN ++ + SA G
Sbjct 493 -VLTLSATQINNSGTLSGAKELVASADTLTTTEKSVTNSDGNLMLNSASSTLAGETSAGG 551
Query 415 DINVSNGAI--IKNVQT-GGDIYLDAQNINVGENTQIANVGLVNLNAAAAIDIK-KSARV 470
++V ++ QT G + +D QN + + TQ A ++ LNA+ + KS+
Sbjct 552 TVSVKGNSLKTTTTAQTQGNSVSVDVQNAQL-DGTQAAR-DILTLNASEKLTHSGKSSAP 609
Query 471 KAVNDLNIIAKQGLSVADANLVAEKGNMNLQSNSNITLQGTTLDLTKDLNINGTGNVNLS 530
+ G+ VA A +N QS + LT + G ++ ++
Sbjct 610 SLSLSAPELTSSGVLVASA--------LNTQSQT----------LTNSGLLQGEASLTVN 651
Query 531 SLNFSLLNGSSTLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANLIDLKGSNLSGKGD 590
+ QN YS +L D +P I + + N + L ++LS G
Sbjct 652 TQRLD------NQQNGTLYSAADLTLD-----IPDIRNSGLITGDNGLTLNTASLSNPG- 699
Query 591 LKLQGKALNVGADLTAGKSLNLTATQSDLILNKTLNAQGNIDIASLDGKLNATGLNATSS 650
K+ LNV A G L QG +A L+ +
Sbjct 700 -KITADTLNVRATTLDGDGL----------------LQGAAALALAGDTLSQGSHGRWLT 742
Query 651 QGKLSIFGAKDTVLTNSGTVK---TTLKGNQGVNVGTI-STGNLTLQNTVLESQNGAIVV 706
G LS+ G L +GT + T++ ++ N G++ +TGNLT T + G I+
Sbjct 743 AGDLSLRGK---TLNTAGTTQGQNLTVQADRWANSGSVLATGNLTASATGQLTSTGDIM- 798
Query 707 TSEGQNTLTDSIITAKGNIELFAKDNLTLDGIKSSSQQHTALNSKKNIYINSQAGTGDSV 766
S+G TL + +G+ L + L+LDG S T + ++ S +G
Sbjct 799 -SQGDTTLNAATTDNRGS--LLSAGTLSLDG-NSLDNSGTVQGNHVTLHHRSTDNSGTVT 854
Query 767 NFSSTKITELNSTGTLSLISDKNQNLQNTRLTGGAILLEAGGTLNTPKVIEFNATGSNLL 826
S L+L S L+ +++L AG N+ ++ G N+
Sbjct 855 GLSG-----------LTLHSADGLTNSGALLSQNSLVLSAGDVTNSGRI-----QGQNIT 898
Query 827 KNDSKLNSLNGDLSIQTKESLTIDPNI-----HTLKAIGDIELASK----QGTL---ILA 874
+ S L S +G + +LT+ ++ + A+GD L K QG + L
Sbjct 899 LDASSLTS-SGAVQSALDLALTLSGDVIAATGSKITALGDARLTGKVLGNQGLISAKTLE 957
Query 875 GYGGQAGNGSE----KVLNLTTTGGGISLEGASVELQGAQLNAEKNIKILANNENIQIIS 930
G N E LN+T +G +L+ L G LN N + ++N+ +Q
Sbjct 958 VNGDSLSNSGEISGVNSLNVTLSG---NLQQHGKMLTGGALNV--NARDISNSGQLQ--G 1010
Query 931 IKNKLNNSKLSDSNKL-------LVDLVEIDNKLKKISINNQYTELFLADVKILENAYDI 983
N++ S L++S ++ L L + N+ + ++ + L +L N I
Sbjct 1011 ADNRITASSLANSGRVQGESGLTLTLLNALTNQTSGVLLSQNVSAL---SAPVLTNDGTI 1067
Query 984 AFNFNPSAYKEDASYRKG---SDKDIQFFNEVYDGFVKKYSDIIEPNIYSQQLNGTKYST 1040
N + ++ G S ++ F Y G + + N+ NGT +
Sbjct 1068 QGNGKTTLSAATQAHNSGKILSGGELTFTTPDYSGSGWLQATDLLLNVAKLAGNGTVMAA 1127
Query 1041 QISIAVPFGDGDYARKEDILSPNGYFKYKYDQNKIRSEINYLSQLNGYEHFSSKLVSNSG 1100
+ + L+ G F+ +QLN +++ ++NSG
Sbjct 1128 NQATLTG----------NSLTNRGLFQ--------------AAQLN----VNTQTITNSG 1159
Query 1101 SIDITSSKGISISGS-----------------ELISKKGLVNIEALGALSQNYTS--TIH 1141
++ ++G++I G+ E++S G + ALG L+ T T
Sbjct 1160 TL--LGNQGLTIKGNNLNNAGGKVFSGGDMLAEMVSLSGAGQLVALGNLTLKLTRGLTAQ 1217
Query 1142 GKDNKPKTLGASIIIDGSQDFYDKGNENDQKYRFRTILKPTLINGDKGVTIRATGNSNQD 1201
G K L S D + +GN R L G+ + +G
Sbjct 1218 GVIAANKQLSVSSQGDITNGATLQGNGITLNAAGRLTNNGQLTAGNGTTALSGSG----- 1272
Query 1202 NLVLQATGITAANGDVRIEANKNILFDAAIEQSYDRSTTTEKKSSWGGLKKKYITTVSEN 1261
+ + A+G A GDV + + +I DA + +T + ++ G + + N
Sbjct 1273 -IAMNASGSLQAGGDVSLTSRGDITLDA-----FTGTTGSLMLTAAGAVINTALLYAGNN 1326
Query 1262 NQANAASV-----DISGKNIFIESKEKNPANNIDIY--SGKFIANGGQVSILSGGNINLY 1314
A+++ D+ + + K+ + A N ++ SG G ++I +G +N
Sbjct 1327 LSLFASTIRNHHGDMLAGDSLVMQKDVSGAANAEVINTSGNIETTRGDITIRTGHLLN-- 1384
Query 1315 TVQESSSSNEDITKKSSFSGIKYNTSKTNATRNQISELPGILKADYIGIKADNDVRLVGT 1374
E I + S+ ++ A N +S G L D G + G
Sbjct 1385 -------QREGINETKSYIPVENVAVPDGA--NSVSVRVGDLGEDGWGYYVKSWSGTAGG 1435
Query 1375 EFEYLQAAKIQAGRNLSLLTASTTV 1399
F+ A + G LT +T V
Sbjct 1436 GFD-AWAVPTEKGATRKFLTGTTRV 1459
Score = 67.4 bits (163), Expect = 3e-13
Identities = 133/628 (21%), Positives = 239/628 (38%), Gaps = 139/628 (22%)
Query 399 IVNQGVVSPLLLSAQGDINVSNGAIIK---------NVQTGGDIYLDAQNINVGENTQIA 449
I Q V+ P + + D+ + NG+II NV G + N+ + +
Sbjct 1820 IKGQTVMVPEVYLSPKDVTLQNGSIISGQNVHLAGGNVTNSGSTLMAQNNLTIDSADSLG 1879
Query 450 NVGLVNLNAAAAIDIKKSARVKAVNDLNIIAKQ--GLSVADANLVAEKGNMNLQSN---- 503
N+ +NA A+ +K A+ D+N I+ G +V +L N+ S+
Sbjct 1880 NLESGLINAGGALGLK------AMGDINNISATITGKTVRLESLAGNVNNLTRYSHWQLD 1933
Query 504 ---SNITLQGT------------TLDLTKDLNINGTGNVNLSSLNFSLLNGSSTLQNINA 548
++ L+ T +LD+ D NI+ TG + +L+ G+ ++NA
Sbjct 1934 APEDSLALKHTYTGSIASVSAMDSLDIRADKNISVTGAEISAGDRAALIAGNDL--SLNA 1991
Query 549 YSGLNLVWDQTAKALPQISGNVTLEAANLIDLK-GSNLSGKGDLKLQGKALNVGADLTAG 607
++ +++ + +G T+ A + + L G ++S +G G A + AG
Sbjct 1992 IDRVSSRRHANSESHQRSAGLTTITAGDSVMLSAGRDVSSQG----AGIAAEDNITVRAG 2047
Query 608 KSLNLTATQS----------DLILNKTLNAQGNIDIASLDGKLNATGLNATS------SQ 651
+ +NL A +S ++++T+ QG +IAS G + T+ +
Sbjct 2048 RDVNLLAEESVTGSSSYSKKKTVIDETVRQQG-AEIASGGDTTITAGRDITAVASSVTAT 2106
Query 652 GKLSIFGAKDTVLTNSGTVKTTLKGNQGVNVGTISTGNLTLQNTVLESQNGAIVVTSEGQ 711
G +S+ +D LT + T + S G L+ + T S+N A T E
Sbjct 2107 GNISVNAGRDVALTTA-----TESDYHYLETKKKSGGFLSKKTTHTISENSA---TREAG 2158
Query 712 NTLTDSIITAKGNIELFAKDNLTLDGIKSSSQQHTALNSKKNIYINSQAGTGDSVNFSST 771
L+ + +T A DNLT+ G + + +L + ++ + + T S F T
Sbjct 2159 ALLSGNRVTVN------AGDNLTVQGSDVVADRDVSLAAGNHVDVLAATSTDTSWRFKET 2212
Query 772 KITELNSTGTLSLISDKNQNLQNTRLTGGAILLEAGGTLNTPKVIEFNATGSNLLKNDSK 831
K + L TG + ++ + R GT + +T N+ K
Sbjct 2213 KKSGLMGTGGIGFTIGSSKTTHDRR---------EAGTTQSQSASTIGSTAGNVSITAGK 2263
Query 832 LNSLNG-------DLSIQTKESLTIDPNIHTLKAIGDIELASKQG-TLILAGYGGQAGNG 883
++G D+SI T +S+ +DP H + + + K G T+ L+G G A N
Sbjct 2264 QAHISGSDVIANRDISI-TGDSVVVDPG-HDRRTVDEKFEQKKSGLTVALSGTVGSAINN 2321
Query 884 SE--------------KVLNLTTTG----------------GGISLEGASVEL------- 906
+ K L T T G + G S+ L
Sbjct 2322 AVTSAQETKESSDSRLKALQATKTALSGVQAGQAAAMATATGDPNATGVSLSLTTQKSKS 2381
Query 907 ---------QGAQLNAEKNIKILANNEN 925
G+ LNA N+ ++A +N
Sbjct 2382 QQHSESDTVSGSTLNAGNNLSVVATGKN 2409
Score = 66.6 bits (161), Expect = 4e-13
Identities = 244/1217 (20%), Positives = 436/1217 (36%), Gaps = 223/1217 (18%)
Query 673 TLKGNQGVNVGTISTGNLTLQNTVLESQNGAIVVTSEGQNT-LTDSIITAKGNIELFAKD 731
T+KG T+ + L + QNG+I+ GQN L +T G+ L A++
Sbjct 1819 TIKGQ------TVMVPEVYLSPKDVTLQNGSII---SGQNVHLAGGNVTNSGST-LMAQN 1868
Query 732 NLTLDGIKSSSQQHTALNSKKNIYINSQAGTGDSVNFSSTKITELNSTGTLSLISDKNQN 791
NLT+D S + L +N+ G L L + + N
Sbjct 1869 NLTIDSADSLGNLESGL---------------------------INAGGALGLKAMGDIN 1901
Query 792 LQNTRLTGGAILLE--AGGTLNTPKVI--EFNATGSNLLKNDSKLNSLNGDLSIQTKESL 847
+ +TG + LE AG N + + +A +L + S+ S+ +SL
Sbjct 1902 NISATITGKTVRLESLAGNVNNLTRYSHWQLDAPEDSLALKHTYTGSI---ASVSAMDSL 1958
Query 848 TI--DPNIHTLKAIGDIELASKQGTLILAG---------------YGGQAGNGSEKVLNL 890
I D NI A E+++ ++AG + + L
Sbjct 1959 DIRADKNISVTGA----EISAGDRAALIAGNDLSLNAIDRVSSRRHANSESHQRSAGLTT 2014
Query 891 TTTGGGISLE-GASVELQGAQLNAEKNIKILANNENIQIISIKNKLNNSKLSDSNKLLVD 949
T G + L G V QGA + AE NI + A + + +++ ++ +S S ++ +
Sbjct 2015 ITAGDSVMLSAGRDVSSQGAGIAAEDNITVRAGRD-VNLLAEESVTGSSSYSKKKTVIDE 2073
Query 950 LVEIDNKLKKISINNQYTELFLADVKILENAYDIAFNFNPSAYKEDASYRKGSDKDIQFF 1009
V +I+ T D+ + ++ N + +A + D + ++ D +
Sbjct 2074 TVRQQGA--EIASGGDTTITAGRDITAVASSVTATGNISVNAGR-DVALTTATESDYHYL 2130
Query 1010 N--EVYDGFV-KKYSDIIEPNIYSQQLNGTKYSTQISIAVPFGDGDYARKEDILSPNGYF 1066
+ GF+ KK + I N +++ ++++ GD + D+++
Sbjct 2131 ETKKKSGGFLSKKTTHTISENSATREAGALLSGNRVTVNA--GDNLTVQGSDVVADRDVS 2188
Query 1067 KYKYDQNKIRSEINYLSQLNGYEHFSSKLVSNSG-SIDITSSKGI----------SISGS 1115
+ + + + + E S L+ G I SSK S S S
Sbjct 2189 LAAGNHVDVLAATSTDTSWRFKETKKSGLMGTGGIGFTIGSSKTTHDRREAGTTQSQSAS 2248
Query 1116 ELISKKGLVNIEALGALSQNYTSTIHGKDNKPKTLGASIIIDGSQDFYDKGNENDQKYRF 1175
+ S G V+I A + + I +D G S+++D D + +QK
Sbjct 2249 TIGSTAGNVSITAGKQAHISGSDVIANRDIS--ITGDSVVVDPGHDRRTVDEKFEQKKSG 2306
Query 1176 RTILKPTLINGDKGVTIRATGNSNQDNLVLQATGITAANGDVRIEANKNILFDAAIEQSY 1235
T+ ++G G I S Q+ + + A ++A K L Q+
Sbjct 2307 LTVA----LSGTVGSAINNAVTSAQETKESSDSRLKA------LQATKTALSGVQAGQAA 2356
Query 1236 DRSTTTEKKSSWGGLKKKYITTVSENNQANAASVDISGK------NIFIESKEKNPANNI 1289
+T T ++ G +TT +Q ++ S +SG N+ + + KN +N
Sbjct 2357 AMATATGDPNATG--VSLSLTTQKSKSQQHSESDTVSGSTLNAGNNLSVVATGKNRGDN- 2413
Query 1290 DIYSGKFIANGGQVSILSGGNINLYTVQE----SSSSNEDITKKSSFSGIKYNTSKTNAT 1345
G + G Q+ +GGN +L + +++ + T ++S SG S
Sbjct 2414 ---RGDIVIAGSQLK--AGGNTSLDAANDILLSGAANTQKTTGRNSSSGGGVGVSIGAGK 2468
Query 1346 RNQISELPGILKADYIGIKADNDVRLVGTEFEYLQAAKIQAGRNLSLLTASTTVTETLKK 1405
IS + A G + N T + + I +GR+ L A +
Sbjct 2469 GAGISVFASVNAAK--GSEKGNGTEWTETTTDSGKTVTINSGRDTVLNGAQVNGNRIIAD 2526
Query 1406 DKNSVVWQSMQDK------------------GSVTETAQLP--------RFNGPTPPEFK 1439
+ ++ S QD GS+T + + RF+
Sbjct 2527 VGHDLLISSQQDTSKYDSKQTSVAAGGSFTFGSMTGSGYIAASRDKMKSRFDSVAEQTGM 2586
Query 1440 AAGGLIVQIPIGEKDQNKIEIRDQILILANQPGNEYLKQ-LVNRNDVDWQKVILAQKDWD 1498
AG I +G Q + ++ P +L + +D+ + D+
Sbjct 2587 FAGDGGFDITVGRHTQ----LDGAVIASTATPDKNHLDTGTLGFSDLH------NEADYK 2636
Query 1499 YKSQGLTGAGAAIIAIIVVMVTAGAGSAVVGALGGSATTLGGS---AVVMTQAAVT--SL 1553
G++ +G G G + G + GG A TQAAV ++
Sbjct 2637 VSHSGISLSGGGSF-----------GDKFQGNMPGGMISAGGHSGHAEGTTQAAVAEGTI 2685
Query 1554 ATQASVSLINNGGDLGKTLKDLGSKDSVKNL------AASVVTAGLLSQVGSALNLKPDT 1607
+ + N DL + + DS+ + + T GL+S +GS + T
Sbjct 2686 TIRDRDNQKQNPADLSRD--PAHANDSISPIFDKEKEQRRLQTVGLISDIGSQVADIART 2743
Query 1608 SGFSARLLNNFTTAVGSTLVQTAIK-------------------------GGDLEDNLKV 1642
G L A G TL A + G +++ ++
Sbjct 2744 QG-ELNALKAAKEATGETLPANATEKQRQEYLAKLRDTPEYKKEQEKYGTGSEIQLGIQA 2802
Query 1643 ALLA-------GLAGAMQGELASQIGTHLDKVDPNVFEYAIHKIAHAAVGCAVAAATKSS 1695
A A LAGA+ G A ++ L + + A++ IAHA +G AVAA ++
Sbjct 2803 ATAALQGLAGGNLAGALAGASAPELAHLLKSTEKDP---AVNAIAHAILGGAVAAMQGNN 2859
Query 1696 CEAGAIGAGVGEI----VASLMPDPVNGIEYNEDEKTKIRNTGKIVAGVVSAYAGYDVNT 1751
AGA GA GE+ +A ++ V + +E++K I + AG+ G +
Sbjct 2860 VAAGAAGAATGELAARAIAGMLYPGVKQSDLSEEQKQTISTLATVSAGLAGGLTGNSSAS 2919
Query 1752 A---ANSADIAIQNNSL 1765
A A S A+ NN L
Sbjct 2920 AAVGAQSGKNAVDNNYL 2936
Score = 62.0 bits (149), Expect = 1e-11
Identities = 149/718 (21%), Positives = 282/718 (39%), Gaps = 128/718 (18%)
Query 298 IDVKNLGGMYANNIYLLGNEKGLGVSNAG-TIRAVNNLVVTSAGKIEHKGSLESTSNTQG 356
+ ++N + N++L G V+N+G T+ A NNL + SA + G+LES G
Sbjct 1837 VTLQNGSIISGQNVHLAGGN----VTNSGSTLMAQNNLTIDSADSL---GNLESGLINAG 1889
Query 357 ----------LVSIQTTQTGDN-------GNINSSGSITSKSMLSIDAANH---LNITGN 396
+ +I T TG GN+N+ +T S +DA L T
Sbjct 1890 GALGLKAMGDINNISATITGKTVRLESLAGNVNN---LTRYSHWQLDAPEDSLALKHTYT 1946
Query 397 QVIVNQGVVSPLLLSAQGDINVSNGAIIKNVQT----GGDIYLDA-----QNINVGENTQ 447
I + + L + A +I+V+ I + G D+ L+A + +
Sbjct 1947 GSIASVSAMDSLDIRADKNISVTGAEISAGDRAALIAGNDLSLNAIDRVSSRRHANSESH 2006
Query 448 IANVGLVNLNAA---------------AAIDIKKSARVKAVNDLNIIAKQGLS------- 485
+ GL + A A I + + V+A D+N++A++ ++
Sbjct 2007 QRSAGLTTITAGDSVMLSAGRDVSSQGAGIAAEDNITVRAGRDVNLLAEESVTGSSSYSK 2066
Query 486 ---VADANL------VAEKGNMNLQSNSNITLQGTTLDLTKDLNINGTGNVNLSSLNFSL 536
V D + +A G+ + + +IT +++ T ++++N +V L++ S
Sbjct 2067 KKTVIDETVRQQGAEIASGGDTTITAGRDITAVASSVTATGNISVNAGRDVALTTATESD 2126
Query 537 LNGSSTLQNINAYSGLNLVW-----DQTAKALPQISGN-VTLEAANLIDLKGSNLSGKGD 590
+ T + + T +A +SGN VT+ A + + ++GS++ D
Sbjct 2127 YHYLETKKKSGGFLSKKTTHTISENSATREAGALLSGNRVTVNAGDNLTVQGSDVVADRD 2186
Query 591 LKLQ-GKALNVGADLTAGKSLNLTATQSDLILNKTLNAQGNIDIASLDGKLNATGLNATS 649
+ L G ++V A + S T+ ++ G I K A +
Sbjct 2187 VSLAAGNHVDVLAATSTDTSWRFKETKKSGLMGT-----GGIGFTIGSSKTTHDRREAGT 2241
Query 650 SQGKLSIFGAKDTVLTNSGTVKTTLKGNQGVNVGTISTGN----LTLQNTVLESQNGAIV 705
+Q + + T+ + +G V T G Q G+ N +T + V++ +
Sbjct 2242 TQSQ-----SASTIGSTAGNVSITA-GKQAHISGSDVIANRDISITGDSVVVDPGHDRRT 2295
Query 706 VTSEGQNTLTDSIITAKGNIELFAKDNLTL--DGIKSSSQQHTALNSKKNIYINSQAGTG 763
V + + + + G + + +T + +SS + AL + K QAG
Sbjct 2296 VDEKFEQKKSGLTVALSGTVGSAINNAVTSAQETKESSDSRLKALQATKTALSGVQAGQA 2355
Query 764 DSVNFSSTKITELNSTG-TLSLISDKNQNLQNTRLTGGAILLEAGGTLNTPKVIEFNATG 822
++ +T + N+TG +LSL + K+++ Q++ +G TLN + ATG
Sbjct 2356 AAM---ATATGDPNATGVSLSLTTQKSKSQQHSESD-----TVSGSTLNAGNNLSVVATG 2407
Query 823 SNLLKN-------DSKLNSLNGDLSIQTKESLTIDPNIHTLKAIG---------DIELAS 866
N N S+L + G+ S+ + + +T K G + + +
Sbjct 2408 KNRGDNRGDIVIAGSQLKA-GGNTSLDAANDILLSGAANTQKTTGRNSSSGGGVGVSIGA 2466
Query 867 KQGTLIL------AGYGGQAGNGSEKVLNLTTTGGGISL-EGASVELQGAQLNAEKNI 917
+G I A G + GNG+E T +G +++ G L GAQ+N + I
Sbjct 2467 GKGAGISVFASVNAAKGSEKGNGTEWTETTTDSGKTVTINSGRDTVLNGAQVNGNRII 2524
Score = 58.2 bits (139), Expect = 2e-10
Identities = 138/712 (19%), Positives = 275/712 (39%), Gaps = 108/712 (15%)
Query 183 IANPAGINIKGGGFINANKAILTTGKPQLNADGSIQQFVVDQGKITISANSGSSLGLG-- 240
I + +++ GG N+ ++ +++ S+ ++ G I N+G +LGL
Sbjct 1844 IISGQNVHLAGGNVTNSGSTLMAQNNLTIDSADSLGN--LESGLI----NAGGALGLKAM 1897
Query 241 GNKNNADYVDLYARALELNAQLYANKDIQAITGANNISADLQQIST---RTGTGTTPTLA 297
G+ NN + + + L + L N + +T ++ D + S T TG+ +++
Sbjct 1898 GDINNIS-ATITGKTVRLES-LAGN--VNNLTRYSHWQLDAPEDSLALKHTYTGSIASVS 1953
Query 298 IDVKNLGGMYANNIYLLGNEKGLGVSNAGTIRAVNNLVVTSAGKIEHKGSLESTSNTQGL 357
+ +L NI + G E G + + A N+L + + ++ + S S+ Q
Sbjct 1954 A-MDSLDIRADKNISVTGAEISAG--DRAALIAGNDLSLNAIDRVSSRRHANSESH-QRS 2009
Query 358 VSIQTTQTGDN------GNINSSGS-ITSKSMLSIDAANHLN------ITGNQVIVNQGV 404
+ T GD+ +++S G+ I ++ +++ A +N +TG+ +
Sbjct 2010 AGLTTITAGDSVMLSAGRDVSSQGAGIAAEDNITVRAGRDVNLLAEESVTGSSSYSKKKT 2069
Query 405 VSPLLLSAQGDINVSNGAIIKNVQTGGDIYLDAQNINVGENTQIANVGLVNLNAAAAIDI 464
V + QG S G + G DI A ++ N + V L A D
Sbjct 2070 VIDETVRQQGAEIASGGDT--TITAGRDITAVASSVTATGNISVNAGRDVALTTATESDY 2127
Query 465 ------KKSARVKAVNDLNIIAKQGLSVADANLVAEKGNMNLQSNSNITLQGTTLDLTKD 518
KKS + + I++ + +A + + + + N+T+QG+ + +D
Sbjct 2128 HYLETKKKSGGFLSKKTTHTISENS-ATREAGALLSGNRVTVNAGDNLTVQGSDVVADRD 2186
Query 519 LNINGTGNVNL-----------------------SSLNFSLLNGSSTLQNINAYSGLNLV 555
+++ +V++ + F++ GSS + +G
Sbjct 2187 VSLAAGNHVDVLAATSTDTSWRFKETKKSGLMGTGGIGFTI--GSSKTTHDRREAGTTQ- 2243
Query 556 WDQTAKALPQISGNVTLEAANLIDLKGSNLSGKGDLKLQGKALNV--GAD---------- 603
Q+A + +GNV++ A + GS++ D+ + G ++ V G D
Sbjct 2244 -SQSASTIGSTAGNVSITAGKQAHISGSDVIANRDISITGDSVVVDPGHDRRTVDEKFEQ 2302
Query 604 LTAGKSLNLTATQSDLILNKTLNAQGNIDIASLDGKLNA--------TGLNATSSQGKLS 655
+G ++ L+ T I N +AQ + S D +L A +G+ A + +
Sbjct 2303 KKSGLTVALSGTVGSAINNAVTSAQETKE--SSDSRLKALQATKTALSGVQAGQAAAMAT 2360
Query 656 IFGAKDTVLTNSGTVKTTLKGNQGVNVGTISTGNLTLQNTVLESQNGAIVVTSEGQNTLT 715
G + + K Q T+S L N + G + G +
Sbjct 2361 ATGDPNATGVSLSLTTQKSKSQQHSESDTVSGSTLNAGNNLSVVATGKNRGDNRGDIVIA 2420
Query 716 DSIITAKGNIELFAKDNLTLDGIKSSSQQHTALNSKK----NIYINSQAGTGDSV----- 766
S + A GN L A +++ L G +++Q+ T NS + I + G G SV
Sbjct 2421 GSQLKAGGNTSLDAANDILLSG-AANTQKTTGRNSSSGGGVGVSIGAGKGAGISVFASVN 2479
Query 767 --------NFSSTKITELNSTGTLSLISDKNQNLQNTRLTGGAILLEAGGTL 810
N + T +S T+++ S ++ L ++ G I+ + G L
Sbjct 2480 AAKGSEKGNGTEWTETTTDSGKTVTINSGRDTVLNGAQVNGNRIIADVGHDL 2531
Score = 50.8 bits (120), Expect = 3e-08
Identities = 136/704 (19%), Positives = 269/704 (38%), Gaps = 137/704 (19%)
Query 95 GQNVPVVNIQTPTNGVSHNIYKQMDVLPEGVVLNNSRTGANSSLVGTVGANPFLAKGEAR 154
G+ V + ++ N ++ + Q+D + + L ++ TG+ +S+
Sbjct 1909 GKTVRLESLAGNVNNLTRYSHWQLDAPEDSLALKHTYTGSIASV---------------- 1952
Query 155 IILNEVNSSVASRFEGNLEVAGQRADVIIANPAGINIKGGGFINANKAILTTGKPQLNAD 214
S+ R + N+ V G A++ + A + G ++ N + + N++
Sbjct 1953 ----SAMDSLDIRADKNISVTG--AEISAGDRAA--LIAGNDLSLNAIDRVSSRRHANSE 2004
Query 215 GSIQQFVVDQGKITISANSGSSLGLGGNKNNADYVDLYARALELNAQLYANKDI-----Q 269
+ G TI+A L G + ++ A E N + A +D+ +
Sbjct 2005 SHQR----SAGLTTITAGDSVMLSAGRDVSSQG----AGIAAEDNITVRAGRDVNLLAEE 2056
Query 270 AITGANNIS---------ADLQQISTRTGTGTTPTLAIDVKNLGGMYANNIYLLGNEKGL 320
++TG+++ S Q +G TT T D+ + A+++ GN
Sbjct 2057 SVTGSSSYSKKKTVIDETVRQQGAEIASGGDTTITAGRDITAV----ASSVTATGNI--- 2109
Query 321 GVSNAGTIRAVNNLVVTSAGKIEHKGSLESTSNTQGLVSIQTTQT-GDNGNINSSGSITS 379
++ A ++ +T+A + ++ LE+ + G +S +TT T +N +G++ S
Sbjct 2110 ------SVNAGRDVALTTATESDYH-YLETKKKSGGFLSKKTTHTISENSATREAGALLS 2162
Query 380 KSMLSIDAANHLNITGNQVIVNQGVVSPLLLSAQGDINV------SNGAIIKNVQTGGDI 433
+ ++++A ++L + G+ V+ ++ V L+A ++V K + G +
Sbjct 2163 GNRVTVNAGDNLTVQGSDVVADRDV----SLAAGNHVDVLAATSTDTSWRFKETKKSGLM 2218
Query 434 YLDAQNINVGEN-----------TQIANVGLVNLNAA-AAIDIKKSARVKAVNDLNIIAK 481
+G + TQ + + A +I K A ++ ++IA
Sbjct 2219 GTGGIGFTIGSSKTTHDRREAGTTQSQSASTIGSTAGNVSITAGKQAH---ISGSDVIAN 2275
Query 482 QGLSVADANLVAEKGNMNLQSNSNITLQGTTLDLTKDLNINGTGNVNLSSLNFSLLNGSS 541
+ +S+ ++V + G+ T+D + +G ++ ++ N +
Sbjct 2276 RDISITGDSVVVDPGH-----------DRRTVDEKFEQKKSGLTVALSGTVGSAINNAVT 2324
Query 542 TLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANLIDLKGSNLSGKGDLKLQGKALNVG 601
+ Q S L Q K +SG +AA + G A V
Sbjct 2325 SAQETKESSDSRLKALQATKT--ALSGVQAGQAAAMATATG-----------DPNATGVS 2371
Query 602 ADLTAGKSLNLTATQSDLILNKTLNAQGNIDIASLDGKLNATGLNATSSQGKLSIFGAKD 661
LT KS + ++SD + TLNA N+ + ATG N ++G + I G++
Sbjct 2372 LSLTTQKSKSQQHSESDTVSGSTLNAGNNLSVV-------ATGKNRGDNRGDIVIAGSQ- 2423
Query 662 TVLTNSGTVKTTLKGNQGVNVGTISTGNLTLQNTVLESQNGAIVVTSEGQNTLTDSIITA 721
+G + N + G +T T +N+ S G + V SI
Sbjct 2424 ---LKAGGNTSLDAANDILLSGAANTQKTTGRNS---SSGGGVGV----------SIGAG 2467
Query 722 KG-NIELFAKDNLTLDGIKSSSQQ--HTALNSKKNIYINSQAGT 762
KG I +FA N K + + T +S K + INS T
Sbjct 2468 KGAGISVFASVNAAKGSEKGNGTEWTETTTDSGKTVTINSGRDT 2511
Score = 44.7 bits (104), Expect = 2e-06
Identities = 121/518 (23%), Positives = 190/518 (37%), Gaps = 105/518 (20%)
Query 161 NSSVASRFEGNLEVAGQRADVIIANPAGINIKGGGFINANKAILTTGKPQLNADGSIQQF 220
N AS + V G+ + A N G ++ N + L+ P L DG+IQ
Sbjct 1013 NRITASSLANSGRVQGESGLTLTLLNALTNQTSGVLLSQNVSALSA--PVLTNDGTIQ-- 1068
Query 221 VVDQGKITISA-----NSGSSLGLGG-NKNNADYVD---LYARALELN-AQLYANKDIQA 270
GK T+SA NSG L G DY L A L LN A+L N + A
Sbjct 1069 --GNGKTTLSAATQAHNSGKILSGGELTFTTPDYSGSGWLQATDLLLNVAKLAGNGTVMA 1126
Query 271 ITGANNISADLQQISTRTGTGTTPTLAIDVKNLGGMYANNIYLLGNE----KGLGVSNAG 326
A L T G L ++ + + N+ LLGN+ KG ++NAG
Sbjct 1127 ANQATLTGNSL----TNRGLFQAAQLNVNTQTI----TNSGTLLGNQGLTIKGNNLNNAG 1178
Query 327 TIRAVNNLVVTSAGKIEHKGSLESTSN-----TQGLVSIQTTQTGDNGNINSSGSITSKS 381
++ + G L + N T+GL + +++S G IT+ +
Sbjct 1179 GKVFSGGDMLAEMVSLSGAGQLVALGNLTLKLTRGLTAQGVIAANKQLSVSSQGDITNGA 1238
Query 382 ML-----SIDAANHLNITGNQVIVNQGVVSPLLLSAQGDINVSNGAIIKNVQTGGDIYLD 436
L +++AA L G Q+ G + LS G ++G++ Q GGD+ L
Sbjct 1239 TLQGNGITLNAAGRLTNNG-QLTAGNGTTA---LSGSGIAMNASGSL----QAGGDVSLT 1290
Query 437 AQNINVGENTQIANVGLVNLNAAAAIDIKKSARVKAVNDLNIIAK-----QGLSVADANL 491
++ ++ + G + L AA A+ +A + A N+L++ A G +A +L
Sbjct 1291 SRG-DITLDAFTGTTGSLMLTAAGAVI--NTALLYAGNNLSLFASTIRNHHGDMLAGDSL 1347
Query 492 VAEKGNMNLQSNSNITLQGTTLDLTKDLNINGTGNVNLSSLNFSLLNGSSTLQNINAYSG 551
V +K + I G D+ I TG++ + ++N+ G
Sbjct 1348 VMQKDVSGAANAEVINTSGNIETTRGDITIR-TGHLLNQREGINETKSYIPVENVAVPDG 1406
Query 552 LNLV------------------WDQTAK------ALPQ---------------------- 565
N V W TA A+P
Sbjct 1407 ANSVSVRVGDLGEDGWGYYVKSWSGTAGGGFDAWAVPTEKGATRKFLTGTTRVDVGATGG 1466
Query 566 ----ISGNVTLEAANLIDLKGSNLSGKGDLKLQGKALN 599
+GN L A+ +D GS+L G + L G LN
Sbjct 1467 DARISAGNNLLIDADKLDNTGSHLLASGFVSLSGSQLN 1504
Score = 38.5 bits (88), Expect = 1e-04
Identities = 44/174 (25%), Positives = 67/174 (39%), Gaps = 18/174 (10%)
Query 77 NSANAGNR-PVIGVGQNSQGQN---VPVVNIQTPTNGVSHNIYKQMDVLPEGVVLNNSRT 132
++ NAGN V+ G+N +G N + + Q G + ++ D+L G T
Sbjct 2393 STLNAGNNLSVVATGKN-RGDNRGDIVIAGSQLKAGG-NTSLDAANDILLSGAANTQKTT 2450
Query 133 GANSSLVGTVGANPFLAKGEARIILNEVNSSVASRFEGN----LEVAGQRADVIIANPAG 188
G NSS G VG + KG + VN++ S +GN E + N
Sbjct 2451 GRNSSSGGGVGVSIGAGKGAGISVFASVNAAKGSE-KGNGTEWTETTTDSGKTVTINSGR 2509
Query 189 INIKGGGFINANKAILTTGKPQLNAD-------GSIQQFVVDQGKITISANSGS 235
+ G +N N+ I G L + S Q V G T + +GS
Sbjct 2510 DTVLNGAQVNGNRIIADVGHDLLISSQQDTSKYDSKQTSVAAGGSFTFGSMTGS 2563
Score = 28.5 bits (62), Expect = 0.16
Identities = 108/531 (20%), Positives = 192/531 (36%), Gaps = 94/531 (18%)
Query 317 EKGLGVSNAGTIRAVNNLVVTSAGKIEHKG-----SLESTSNT-----QGLVSIQTTQTG 366
+ GL V+ +GT+ + N VTSA + + +L++T G + T TG
Sbjct 2304 KSGLTVALSGTVGSAINNAVTSAQETKESSDSRLKALQATKTALSGVQAGQAAAMATATG 2363
Query 367 DNGNINSSGSITSKSMLSIDAANHLNITGNQVIVNQGVVSPLLLSAQGDINVSNGAIIKN 426
D S S+T++ S + ++G+ + + +GD
Sbjct 2364 DPNATGVSLSLTTQKSKSQQHSESDTVSGSTLNAGNNLSVVATGKNRGD----------- 2412
Query 427 VQTGGDIYLDAQNINVGENTQIANVGLVNLNAAAAIDIKKSARVKAVND---LNIIAKQG 483
GDI + + G NT + + L+ AA K + R + ++I A +G
Sbjct 2413 --NRGDIVIAGSQLKAGGNTSLDAANDILLSGAANTQ-KTTGRNSSSGGGVGVSIGAGKG 2469
Query 484 LSVA-----DANLVAEKGNMNLQSNSNITLQGTTLDLT--KDLNINGT---GNVNLSSLN 533
++ +A +EKGN + T G T+ + +D +NG GN ++ +
Sbjct 2470 AGISVFASVNAAKGSEKGN-GTEWTETTTDSGKTVTINSGRDTVLNGAQVNGNRIIADVG 2528
Query 534 FSLLNGSSTLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANLIDLKGSNLSGKGDLKL 593
LL S Q+ + Y QT+ A ++ + I + + D
Sbjct 2529 HDLLISSQ--QDTSKYDS-----KQTSVAAGGSFTFGSMTGSGYIAASRDKMKSRFDSVA 2581
Query 594 QGKAL---NVGADLTAGKSLNLTATQSDLILNKTLNAQGNIDIASLDGKLNATGLNATSS 650
+ + + G D+T G+ L +I + + ++D G L + L+ +
Sbjct 2582 EQTGMFAGDGGFDITVGRHTQLDGA---VIASTATPDKNHLDT----GTLGFSDLH-NEA 2633
Query 651 QGKLSIFGAKDTVLTNSGTVKTTLKGNQGVNVGTISTGNLTLQNTVLESQNGAIVVTSEG 710
K+S G L+ G+ +GN + G IS G G
Sbjct 2634 DYKVSHSGIS---LSGGGSFGDKFQGN--MPGGMISAGG------------------HSG 2670
Query 711 QNTLTDSIITAKGNIELFAKDNLTLDGIKSSSQQHTALNSKKNIYINSQAGTGDSVNFSS 770
T A+G I + +DN +Q+ A S+ + N DS++
Sbjct 2671 HAEGTTQAAVAEGTITIRDRDN---------QKQNPADLSRDPAHAN------DSISPIF 2715
Query 771 TKITELNSTGTLSLISDKNQNLQNTRLTGGAILLEAGGTLNTPKVIEFNAT 821
K E T+ LISD + + T G + T + + NAT
Sbjct 2716 DKEKEQRRLQTVGLISDIGSQVADIARTQGELNALKAAKEATGETLPANAT 2766
Score = 26.6 bits (57), Expect = 0.61
Identities = 29/107 (27%), Positives = 44/107 (41%), Gaps = 9/107 (8%)
Query 1520 TAGAGSAVVGALGGSATT--LGGSAVVMTQAAVTSLATQASVSLINNGGDLGKTLKDLGS 1577
T GAG G + T + G+ + +T +TS + S S ++ D G+
Sbjct 411 TLGAGRDATVKTGTFSNTGAVQGNGLKVTATDLTSTGSIKSGSTLDISARNATLSGDAGA 470
Query 1578 KDSVKNLAASVVTAGLLSQVGSALNLKPDTSGFSARLLNNFTTAVGS 1624
KDS A V +G L G ++ D SA +NN T G+
Sbjct 471 KDS-----ARVTVSGTLENRGRLVS--DDVLTLSATQINNSGTLSGA 510
Score = 25.8 bits (55), Expect = 1.0
Identities = 38/159 (24%), Positives = 60/159 (38%), Gaps = 30/159 (19%)
Query 1504 LTGAGAAIIAIIVVMVTAGAGSAVVGALGGSATTLGGSAVVMTQAAVTSLATQASVSLIN 1563
LT A+++ + T+GA +A + TT GG + + +V S +N
Sbjct 353 LTAGQNAMLSAQHLNQTSGAVNAAENV---TLTTTGG--ITLKGRSVAGKTLTVSSGSLN 407
Query 1564 NGGDLGKTLKDLGSKDSVKNLAASVVTAGLLSQVGSALNLKPDTSGFSARLLNNFTTAVG 1623
NGG LG +D+ V G S G+ G ++ T+ G
Sbjct 408 NGGTLG------AGRDAT-------VKTGTFSNTGAV-------QGNGLKVTATDLTSTG 447
Query 1624 STLVQTAIKGGDLEDNLKVALLAGLAGAMQGELASQIGT 1662
S G L+ + + A L+G AGA + GT
Sbjct 448 SIK-----SGSTLDISARNATLSGDAGAKDSARVTVSGT 481
Score = 25.0 bits (53), Expect = 1.8
Identities = 16/44 (36%), Positives = 21/44 (48%), Gaps = 9/44 (20%)
Query 1187 DKGVTIR-ATGNSNQDNLVLQATGITAANGDVRIEANKNILFDA 1229
+KG T + TG + D + A GD RI A N+L DA
Sbjct 1445 EKGATRKFLTGTTRVD--------VGATGGDARISAGNNLLIDA 1480
>Q3YL96 Toxin CdiA [Escherichia coli]
Length=3132
Score = 235 bits (600), Expect = 2e-64
Identities = 257/905 (28%), Positives = 405/905 (45%), Gaps = 148/905 (16%)
Query 56 LVASMSLWMPLAPVYAQIQADNSANAGNRPVIGVGQNSQGQNVPVVNIQTPTN-GVSHNI 114
LV+++ PL P + P G G + VPVVNI TP G+SHN
Sbjct 16 LVSAIIAGQPLLPAVGAVIT---------PQNGAGMDKAANGVPVVNIATPNGAGISHNR 66
Query 115 YKQMDVLPEGVVLNNSRTGAN-SSLVGTVGANPFL-AKGEARIILNEVNSSVASRFEGNL 172
+ +V EG++LNN+ N + L G + NP L A GEA+ I+NEV S +G
Sbjct 67 FTDYNVGKEGLILNNATGKLNPTQLGGLIQNNPNLKAGGEAKGIINEVTGGKRSLLQGYT 126
Query 173 EVAGQRADVIIANPAGINIKGGGFINANKAILTTGKPQLNADGSIQQFVVDQGKITISAN 232
EVAG+ A+V++ANP GI G GFIN A LTTGKP +NADGS+Q V +G ITI+
Sbjct 127 EVAGKAANVMVANPYGITCDGCGFINTPHATLTTGKPVMNADGSLQALEVTEGSITIN-- 184
Query 233 SGSSLGLGGNKNNADYVDLYARALELNAQLYANKDIQAITGANNISADLQQISTRTGTGT 292
G G + +D V + ARA E+NA L+A KD+ GAN I+AD ++S G G
Sbjct 185 -----GAGLDGTRSDAVSIIARATEVNAALHA-KDLTVTAGANRITAD-GRVSALKGEGN 237
Query 293 TPTLAIDVKNLGGMYANNIYLLGNEKGLGVSNAGTIRAVNNLVVTSAGKIEHKGSLESTS 352
P +A+D LGGMYA I+L E G+GV+ +++++S+GK+ K SL +
Sbjct 238 VPKVAVDTGALGGMYARRIHLTSTESGVGVNLGNLYAREGDIILSSSGKLVLKNSLAGGN 297
Query 353 NTQGLVSIQTTQTGDNGNINSSGSITSKSMLSIDAANHLNITGNQVIVNQGVVSPLLLSA 412
TT TG +++ SG + LS+ L + ++++ ++ L+LS+
Sbjct 298 ---------TTVTGT--DVSLSGDNKAGGNLSVTGTTGLTLNQSRLVTDKN----LVLSS 342
Query 413 QGDINVSNGAIIKNVQTGGDIYLDAQNINVGENTQIANVGLVNLNAAAAIDIKKSARVKA 472
G I V NG + G + L AQ++N T +NAA ++ +
Sbjct 343 SGQI-VQNGG---ELTAGQNAMLSAQHLNQTSGT---------VNAA------ENVTLTT 383
Query 473 VNDLNIIAKQGLSVADANLVAEKGNMNLQSNSNITLQGTTLDLTKDLNINGTGNVNLSSL 532
+D + +G SVA L G++N G TL +D +
Sbjct 384 TDDTTL---KGRSVAGKTLTVSSGSLN---------NGGTLVAGRDATVK---------- 421
Query 533 NFSLLNGSSTLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANLIDLKGSNLSGKGDLK 592
+ T N G L T ++ ++++ + +D+ N + GD
Sbjct 422 -------TGTFSNTGTVQGNGLKVTAT-----DLTSTGSIKSGSTLDISARNATLSGDAG 469
Query 593 LQGKAL--------NVGADLTAGKSLNLTATQSDLILNKTLNAQGNIDIASLDGKLNATG 644
+ +AL N G L + L L+ATQ +N + G ++ + L T
Sbjct 470 AKDRALVTVSGTLENRGR-LVSDDVLTLSATQ----INNSGTLSGAKELVASADTLTTTE 524
Query 645 LNATSSQGKLSIFGAKDTV---LTNSGTVKTTLKGNQGVNVGTIST-GN---LTLQNTVL 697
+ T+S G L + A T+ + GTV ++KGN T T GN + +QN L
Sbjct 525 KSVTNSDGNLMLDSASSTLAGETSAGGTV--SVKGNSLKTTTTAQTQGNSVSVDVQNAQL 582
Query 698 E-SQNGAIVVTSEGQNTLTDSIITAKGNIELFAKDNLTLDGIKSSSQQHTALNSKKNIYI 756
+ +Q ++T LT S ++ ++ L A + LT G+ S ALN++
Sbjct 583 DGTQAARDILTLNASEKLTHSGKSSAPSLSLSAPE-LTSSGVLVGS----ALNTQSQTLT 637
Query 757 NSQAGTGDSVNFSSTKITELNSTGTLSLISDKNQNLQNTRLTG-----GAILLEAGGTLN 811
NS G + +T+ + GTL +D ++ + R +G ++L A N
Sbjct 638 NSGLLQGKASLTVNTQRLDNQQNGTLYSAADLTLDIPDIRNSGLITGDNGLMLNAVSLSN 697
Query 812 TPKVI-EFNATGSNLLKNDSKLNSLNGDLSIQTKESLTIDPNIHTLKAIGDIELASK--- 867
K+I + + + L D L G L++ ++L++ N L A GD+ L K
Sbjct 698 PGKIIADTLSVRATTLDGDGLLQGA-GALAL-AGDTLSLGSNGRWLTA-GDLSLRGKTLH 754
Query 868 -----QGTLILAGYGGQAGNGSEKVL---------NLTTTG-----GGISLEGASVELQG 908
QG + A +GS + LT+TG G +L A+ + +G
Sbjct 755 TAGTTQGQNLTVQADRWANSGSVQATGNLTASATGQLTSTGDIMSQGDTTLNAATTDNRG 814
Query 909 AQLNA 913
+ L+A
Sbjct 815 SLLSA 819
Score = 87.4 bits (215), Expect = 2e-19
Identities = 211/915 (23%), Positives = 363/915 (40%), Gaps = 133/915 (15%)
Query 72 QIQADNSANA----GNRPVIGVGQNSQG-QNVPVVNIQTPTNGVSHNI----YKQMDVLP 122
+I AD +A GN P + V + G +++ + +GV N+ ++ D++
Sbjct 222 RITADGRVSALKGEGNVPKVAVDTGALGGMYARRIHLTSTESGVGVNLGNLYAREGDIIL 281
Query 123 EG---VVLNNSRTGANSSLVGTVGANPFLAKGEARIILNEVNSSVASRFEGNLEVAGQRA 179
+VL NS G N+++ GT +V+ S ++ GNL V G
Sbjct 282 SSSGKLVLKNSLAGGNTTVTGT-----------------DVSLSGDNKAGGNLSVTGTTG 324
Query 180 DVI----IANPAGINIKGGGFINANKAILTTGKPQLNADGSIQQFVVDQGKITISAN--- 232
+ + + + G I N LT G+ NA S Q G + + N
Sbjct 325 LTLNQSRLVTDKNLVLSSSGQIVQNGGELTAGQ---NAMLSAQHLNQTSGTVNAAENVTL 381
Query 233 -SGSSLGLGGNKNNADYVDLYARALELNAQLYANKDIQAITGANNISADLQQISTR-TGT 290
+ L G + + + +L L A +D TG + + +Q + T T
Sbjct 382 TTTDDTTLKGRSVAGKTLTVSSGSLNNGGTLVAGRDATVKTGTFSNTGTVQGNGLKVTAT 441
Query 291 GTTPTLAIDVKNLGGMYANNIYLLGNEKGLGVSNAGTIRAVNNLVVTSAGKIEHKGSLES 350
T T +I + + A N L G+ AG A + +VT +G +E++G L S
Sbjct 442 DLTSTGSIKSGSTLDISARNATLSGD--------AG---AKDRALVTVSGTLENRGRLVS 490
Query 351 TSNTQGLVSIQTTQTGDNGNINSSGS-ITSKSMLSIDAANHLNITGNQVIVNQGVVSPLL 409
++++ TQ ++G ++ + + S L+ + N GN ++ +
Sbjct 491 DD----VLTLSATQINNSGTLSGAKELVASADTLTTTEKSVTNSDGNLMLDSASSTLAGE 546
Query 410 LSAQGDINVSNGAI--IKNVQT-GGDIYLDAQNINVGENTQIANVGLVNLNAAAAIDIK- 465
SA G ++V ++ QT G + +D QN + + TQ A ++ LNA+ +
Sbjct 547 TSAGGTVSVKGNSLKTTTTAQTQGNSVSVDVQNAQL-DGTQAAR-DILTLNASEKLTHSG 604
Query 466 KSARVKAVNDLNIIAKQGLSVADANLVAEKGNMN---LQSNSNITLQGTTLDLTKDLNIN 522
KS+ + G+ V A + N LQ +++T+ LD ++ +
Sbjct 605 KSSAPSLSLSAPELTSSGVLVGSALNTQSQTLTNSGLLQGKASLTVNTQRLDNQQNGTLY 664
Query 523 GTGNVNLSS---LNFSLLNGSSTLQNINAYSGLN---LVWDQTAKALPQISGNVTLEAAN 576
++ L N L+ G + L +NA S N ++ D + + G+ L+ A
Sbjct 665 SAADLTLDIPDIRNSGLITGDNGLM-LNAVSLSNPGKIIADTLSVRATTLDGDGLLQGAG 723
Query 577 LIDLKGSNLS--------GKGDLKLQGKALNVGADLTAGKSLNLTATQSDLILNK-TLNA 627
+ L G LS GDL L+GK L+ A T G++L + Q+D N ++ A
Sbjct 724 ALALAGDTLSLGSNGRWLTAGDLSLRGKTLHT-AGTTQGQNLTV---QADRWANSGSVQA 779
Query 628 QGNIDIASLDGKLNATGLNATSSQGKLSIFGAKDT---VLTNSGTVKTTLKGNQGVNVGT 684
GN+ AS G+L +TG SQG ++ A L ++GT+ +L GN N GT
Sbjct 780 TGNLT-ASATGQLTSTG--DIMSQGDTTLNAATTDNRGSLLSAGTL--SLDGNSLDNSGT 834
Query 685 ISTGNLTLQNTVLESQNGAIVVTSEGQNTLTDSIITAKGNIELFAKDNLTLDGIKSSSQQ 744
+ ++T++ QNG VT+ G TLT I A LTL +
Sbjct 835 VQGNHVTIR------QNG---VTNSG--TLTG--IAA-----------LTLAARMDMASP 870
Query 745 HTALNSKKNIYINSQAGTGDSVNFSSTKITELNSTGTLSLISDKNQNLQNTRLTGGAILL 804
AL + + S T + + +++ + + T L + + + G + L
Sbjct 871 QPALMNNGGSLLTSGDLTITAGSLANSGAIQAADSLTARLTGELVSTAGSKVTSNGEMAL 930
Query 805 EAGGTLNTPKVIEFNATGSNLLKNDSKLNSLNGDLSIQTKESLTIDPNIHTLKAIGDIEL 864
A N+ + I N T K NSL I ++LT+ N TL +L
Sbjct 931 SALNLSNSGQWIAKNLT--------LKANSLTSAGDITGVDALTLTVN-QTLNNHASGKL 981
Query 865 ASKQGTLILAGY-----GGQAGNGSEKVLNLTTTGGGISLEGASVELQGAQLNAEKNIKI 919
S G L L G GN + T GG + E ++ G N + +
Sbjct 982 LSA-GVLTLKADSVKNDGQLQGNATTITAGQLTNGGHLQGETLTLAASGGVNNRSGGVLM 1040
Query 920 LANNENIQIISIKNK 934
N N+ ++ N+
Sbjct 1041 SRNALNVSTATLSNQ 1055
Score = 70.9 bits (172), Expect = 2e-14
Identities = 152/770 (20%), Positives = 283/770 (37%), Gaps = 149/770 (19%)
Query 298 IDVKNLGGMYANNIYLLGNEKGLGVSNAGT-IRAVNNLVVTSAGKIEHKGSLESTSNTQG 356
I + N + NN+ L G ++N+G+ I A N+L++ G I++ + N G
Sbjct 1816 ITLHNGSVISGNNVQLAGGN----ITNSGSSINAQNDLLLDRTGSIDNLNA--GLINAGG 1869
Query 357 LVSIQTTQTGDNGNINSSGSITSKSMLSIDAA-------------------NHLNITGNQ 397
++++ GD GNI+S + S +S+++A NH + T
Sbjct 1870 ALNLKAI--GDIGNISS---VISGKTVSLESATGNISNLTRTEQWAMNNGYNHFSGTDTG 1924
Query 398 VIVNQGVVSPLLLSAQGDINVSNGAIIKN----VQTGGDIYLDAQNINVGENTQIANVGL 453
+ L + A GDI+++ A+ + G D+ ++A I GE + G
Sbjct 1925 PLAAVRATDSLFMGAAGDISITGAAVSAGDSVLLAAGNDLNMNA--IQAGERRRYGGSGW 1982
Query 454 VNLNAAA-AIDIKKSARVKAVNDLN-----IIAKQGLSVA---DANLVAEK--------- 495
+A A + S + A D+N I A+ + + D N+ AE
Sbjct 1983 YETHAVAPTVTAGNSLMLSAGRDVNSQAAGITAENSMDIRAGRDVNMAAESTGAGDHDST 2042
Query 496 --------------------GNMNLQSNSNITLQGTTLDLTKDLNINGTGNVNLSSLNFS 535
G++ + + +IT T + D+ +N ++ L + S
Sbjct 2043 FSMKTVHDSVRQQGTDMTSGGDITVTAGRDITSVATAVTAKGDIRVNAGHDIVLGTATES 2102
Query 536 LLNGSSTLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANLIDLKGSNLSGKGDLKLQG 595
+ S + + N L+ QT + + + S VT E KGS LSG G
Sbjct 2103 DYHYSESGETRN-----RLLSHQTTRTITEDS--VTRE-------KGSLLSGNRVTVNAG 2148
Query 596 KALNV-GADLTAGKSLNLTATQS-DLILNKTLNAQGNIDIASLDGKLNATGLNATSSQGK 653
L V G+D+ A + ++L A D++ + + G G+ T+ K
Sbjct 2149 NNLTVQGSDVVADRDVSLAADNHVDVLAATSTDTSWRFKETKTSGLTGTGGIGFTTGSSK 2208
Query 654 LSIFGAKDTVLTNSGTVKT--TLKGNQGVNVGT---ISTGNLTLQNTVLESQNGAIVVTS 708
+ ++ T S + T + GN + G IS ++ + + + +V
Sbjct 2209 TT-HDRREAGTTQSQSASTIGSTAGNVSITAGKQAHISGSDVIANRDISITGDSVVVDPG 2267
Query 709 EGQNTLTDSIITAKGNIELFAKD----------NLTLDGIKSSSQQHTALNSKKNIYINS 758
+ T+ + K + + + + ++S + AL + +
Sbjct 2268 HDRRTVDEKFEQKKSGLTVALSGAVGSAINNAVTMAREAKETSDSRLAALKGTQAVLSGV 2327
Query 759 QAGTGDSVNFSSTKITELNSTGTLSLISDKNQNLQNTRLTGGAILLEAGGTLNTPKVIEF 818
QAG + S + N+ +S+ + Q+ T+ + +G TL+ +
Sbjct 2328 QAGVNHGLQQQSA---DPNNGIGVSISLNHQQSKSETKYQHDIV---SGSTLSAGNNVSV 2381
Query 819 NATGSNLLKNDSKLNSLNGDLSIQTKESLTIDPNIHTLKAIGDIELASKQGTLILAGYGG 878
ATG N N+S GD+ I + + N +L A DI LA+ T G
Sbjct 2382 TATGKNKDHNNS------GDMLITGSQIKS--GNDTSLNAQNDILLAAAADTRQTTGKNS 2433
Query 879 QAGNGSEKVLNLTTTGGGISL-----------EGASVELQGAQLNAEKNIKILANNENI- 926
G G T GGG+S+ +G L+A KN+ + + +
Sbjct 2434 SKGGGVGVSFGGGTNGGGLSIFAGINGSEGREKGNGTTWTETTLDAGKNVSLTSGRDTTL 2493
Query 927 ---------QIISIKNKLNNSKLSDSNKLLVDLVEIDNKLKKISINNQYT 967
+ N L S L DS++ D++ +++ +T
Sbjct 2494 SGAQVSGEKVTADVGNNLTISSLQDSDR-------YDSRQNRVAAGGSFT 2536
Score = 67.8 bits (164), Expect = 2e-13
Identities = 180/853 (21%), Positives = 326/853 (38%), Gaps = 129/853 (15%)
Query 134 ANSSLVGTVGANPFLAKGEARIILNEVNSSVASRFEGN--------LEVAGQRA--DVII 183
A+S+L G A G + N + ++ ++ +GN ++ G +A D++
Sbjct 539 ASSTLAGETSAG-----GTVSVKGNSLKTTTTAQTQGNSVSVDVQNAQLDGTQAARDILT 593
Query 184 ANPAGINIKGGGFINANKAILTTGKPQLNADGSIQQFVVDQGKITISANSGSSLGLGGNK 243
N + G ++ L+ P+L + G + ++ T++ NSG G
Sbjct 594 LNASEKLTHSG---KSSAPSLSLSAPELTSSGVLVGSALNTQSQTLT-NSGLLQGKASLT 649
Query 244 NNADYVD------LYARALELNAQLYANKDIQAITGANNISADLQQISTRTGTGTTPTLA 297
N +D LY+ A +L + ++ ITG N + + +S G TL+
Sbjct 650 VNTQRLDNQQNGTLYSAA-DLTLDIPDIRNSGLITGDNGLMLNAVSLSN-PGKIIADTLS 707
Query 298 IDVKNLGG----MYANNIYLLGNEKGLGVSNAGTIRAVNNLVVTSAGKIEHKG-SLESTS 352
+ L G A + L G+ LG SN + +AG + +G +L +
Sbjct 708 VRATTLDGDGLLQGAGALALAGDTLSLG-SNGRWL---------TAGDLSLRGKTLHTAG 757
Query 353 NTQGL-VSIQTTQTGDNGNINSSGSITSKSMLSIDAANHLNITGNQVIVNQGVVSPLLLS 411
TQG +++Q + ++G++ ++G++T+ + + + + G+ + + L
Sbjct 758 TTQGQNLTVQADRWANSGSVQATGNLTASATGQLTSTGDIMSQGDTTLNAATTDNRGSLL 817
Query 412 AQGDINVSNGAIIKNVQTGGDIYLDAQNINVGENTQIANVGLVNLNAAAAIDIKKSARVK 471
+ G +++ ++ + G+ QN G G+ L AA +D+
Sbjct 818 SAGTLSLDGNSLDNSGTVQGNHVTIRQN---GVTNSGTLTGIAALTLAARMDMASPQPAL 874
Query 472 AVNDLNIIAKQGLSVADANLVAEKGNMNLQSNSNITLQGTTLDLTKDLNINGTGNVNLSS 531
N +++ L++ +L A G + + L G + T + G + LS+
Sbjct 875 MNNGGSLLTSGDLTITAGSL-ANSGAIQAADSLTARLTGELVS-TAGSKVTSNGEMALSA 932
Query 532 LNFS------------LLNGSSTLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANLID 579
LN S N ++ +I L L +QT SG L +A ++
Sbjct 933 LNLSNSGQWIAKNLTLKANSLTSAGDITGVDALTLTVNQTLNN--HASGK--LLSAGVLT 988
Query 580 LKGSNLSGKGDLKLQGKALNVGADLTAGKSLNLTATQSDLILNKTLNAQGNIDIASLDGK 639
LK ++ K D +LQG A + TAG+ N Q + + TL A G ++ S
Sbjct 989 LKADSV--KNDGQLQGNATTI----TAGQLTNGGHLQGETL---TLAASGGVNNRSGGVL 1039
Query 640 LNATGLNATSSQGKLSIFGAKDTVLTNSGTVKTTLKGNQGVNVGT----------ISTGN 689
++ LN +++ L+N GT++ G GV++ +S N
Sbjct 1040 MSRNALNVSTA------------TLSNQGTIQ----GGGGVSLNATDRLQNDGKILSGSN 1083
Query 690 LTLQNTVLESQNGAIVVTS----EGQNTLTDSIITAKGNIELFA---KDNLTLDGIKSSS 742
LTL VL + +V + + NT+ + A G+ ++ + T G
Sbjct 1084 LTLTAQVLANTGSGLVQAATLLLDVVNTVNGGRVLATGSADVKGTTLNNTGTFQGADLLV 1143
Query 743 QQHTALNSKKNIYINSQAGTGDSVNFSSTKITELNSTGTLSLISDKNQNLQNTRLTGGAI 802
HT NS + + G S+ + T L S G L L + TG
Sbjct 1144 NYHTFSNSGTLLGTSGLGVKGSSLLQNGTG--RLYSAGNLLLDAQDFSGQGQVVATGDVT 1201
Query 803 L-----LEAGGTLNTPKVIEFNATGSNLLKNDSKLNSLNGD-LSIQTKESLTIDPNIHTL 856
L L GTL K + + T N + N + GD + + E+ T N TL
Sbjct 1202 LKLIAALTNHGTLAAGKTL--SVTSQNAVTNGGVMQ---GDAMVLGAGEAFT---NNGTL 1253
Query 857 KAIGDIELASKQGTLILAGYGGQAGNGSE-------KVLNLTTTGGGISLEGASVELQGA 909
A + S Q + A QAG + T T G +++ A L A
Sbjct 1254 TAGKGNSVFSAQRLFLNAPGSLQAGGDVSLNSRSDITISGFTGTAGSLTMNVAGTLLNSA 1313
Query 910 QLNAEKNIKILAN 922
+ A N+K+ +
Sbjct 1314 LIYAGNNLKLFTD 1326
Score = 66.6 bits (161), Expect = 4e-13
Identities = 185/822 (23%), Positives = 312/822 (38%), Gaps = 155/822 (19%)
Query 94 QGQNVPVVNIQTPTNGVSHNIYKQMDVLPEGVVLNNSR--TGANSSLVGTVG-ANPFLAK 150
QG+ VN Q N + +Y D+ + + NS TG N ++ V +NP
Sbjct 643 QGKASLTVNTQRLDNQQNGTLYSAADLTLDIPDIRNSGLITGDNGLMLNAVSLSNP---- 698
Query 151 GEARIILNEVNSSVASRF-EGNLEVAGQRA---DVIIANPAGINIKGGGFINANKAILTT 206
+II + ++ + +G L+ AG A D + G + G K + T
Sbjct 699 --GKIIADTLSVRATTLDGDGLLQGAGALALAGDTLSLGSNGRWLTAGDLSLRGKTLHTA 756
Query 207 GKPQ-----LNAD-----GSIQQFVVDQGKITISA-----NSGSSLGLGGNKNNADYVD- 250
G Q + AD GS+Q G +T SA ++G + G NA D
Sbjct 757 GTTQGQNLTVQADRWANSGSVQA----TGNLTASATGQLTSTGDIMSQGDTTLNAATTDN 812
Query 251 ----LYARALELNAQLYANKDIQAITGANNISADLQQISTRTGTGTTPTLAIDVKNLGGM 306
L A L L+ N T N Q T +GT T A+ + M
Sbjct 813 RGSLLSAGTLSLDGNSLDNSG----TVQGNHVTIRQNGVTNSGT-LTGIAALTLAARMDM 867
Query 307 YANNIYLLGNEKGL-----------GVSNAGTIRAVNNLVVTSAGKIEHKGSLESTSNTQ 355
+ L+ N L ++N+G I+A ++L G++ + TSN
Sbjct 868 ASPQPALMNNGGSLLTSGDLTITAGSLANSGAIQAADSLTARLTGELVSTAGSKVTSN-- 925
Query 356 GLVSIQTTQTGDNGN-INSSGSITSKSMLS---IDAANHLNITGNQVIVNQGVVSPLLLS 411
G +++ ++G I + ++ + S+ S I + L +T NQ + N S LLS
Sbjct 926 GEMALSALNLSNSGQWIAKNLTLKANSLTSAGDITGVDALTLTVNQTLNNH--ASGKLLS 983
Query 412 AQGDINVSNGAIIKNVQTGGDIYLDAQNINVGENTQIANVGLVNLNAAAAIDIKKSARVK 471
A G + + +V+ G + +A I G Q+ N G +
Sbjct 984 A-GVLTLK----ADSVKNDGQLQGNATTITAG---QLTNGGHLQ---------------- 1019
Query 472 AVNDLNIIAKQGLSVADANLVAEKGNMNLQSNSNITLQGTTLDLTKDLNINGTGNVNLSS 531
L + A G++ ++ + +N+ S + ++ QGT I G G V+
Sbjct 1020 -GETLTLAASGGVNNRSGGVLMSRNALNV-STATLSNQGT---------IQGGGGVS--- 1065
Query 532 LNFSLLNGSSTLQNI-NAYSGLNLVWDQTAKALPQISGNVTLEAANLID----LKGSNLS 586
LN + LQN SG NL TA+ L + A L+D + G +
Sbjct 1066 -----LNATDRLQNDGKILSGSNLT--LTAQVLANTGSGLVQAATLLLDVVNTVNGGRVL 1118
Query 587 GKGDLKLQGKALN-----VGADLTAGKSLNLTATQSDLILNKTLNAQGNIDIASLDGKLN 641
G ++G LN GADL + + + L+ L +G+ + + G+L
Sbjct 1119 ATGSADVKGTTLNNTGTFQGADLLV--NYHTFSNSGTLLGTSGLGVKGSSLLQNGTGRLY 1176
Query 642 ATG---LNATSSQGKLSIFGAKDTVLTNSGTVKTTLKGNQGVNVGTISTG---NLTLQNT 695
+ G L+A G+ + D L + N GT++ G ++T QN
Sbjct 1177 SAGNLLLDAQDFSGQGQVVATGDVTLKLIAAL---------TNHGTLAAGKTLSVTSQNA 1227
Query 696 VLES--QNGAIVVTSEGQNTLTDSIITAKGNIELFAKDNLTLDGIKS-SSQQHTALNSKK 752
V G +V G+ + +TA +F+ L L+ S + +LNS+
Sbjct 1228 VTNGGVMQGDAMVLGAGEAFTNNGTLTAGKGNSVFSAQRLFLNAPGSLQAGGDVSLNSRS 1287
Query 753 NIYINSQAGTGDSVNFSSTKITELNST-----GTLSLISDKNQNLQNTRLTGGAILL--E 805
+I I+ GT S+ + T LNS L L +D+ N L G ++ + +
Sbjct 1288 DITISGFTGTAGSLTMNVAG-TLLNSALIYAGNNLKLFTDRLHNQHGDILAGNSLWVQKD 1346
Query 806 AGGTLNTPKVIEFNATGSNLLKNDSKLNSLNGDLSIQTKESL 847
+ GT N S ++ + + GD+++ T L
Sbjct 1347 SSGTAN-----------SEIINRSGNIETTRGDITMNTAHLL 1377
Score = 62.8 bits (151), Expect = 7e-12
Identities = 170/841 (20%), Positives = 305/841 (36%), Gaps = 131/841 (16%)
Query 1092 SSKLVSNSGSIDITSSKGISISGSELISKKGLVNIEALGALSQNYTSTIHGKDNKPKTLG 1151
+S + S +G++ IT+ K ISGS++I+ + + G
Sbjct 2224 ASTIGSTAGNVSITAGKQAHISGSDVIANRDI------------------------SITG 2259
Query 1152 ASIIIDGSQDFYDKGNENDQKYRFRTILKPTLING--DKGVTIRATGNSNQDNLVLQATG 1209
S+++D D + +QK T+ + + VT+ D+ + G
Sbjct 2260 DSVVVDPGHDRRTVDEKFEQKKSGLTVALSGAVGSAINNAVTMAREAKETSDSRLAALKG 2319
Query 1210 ITAANGDVRIEANKNILFDAAIEQS-YDRSTTTEKKSSWGGLKKKY-ITTVSENNQANAA 1267
A V+ N + +A + S + + S K ++ I + S + N
Sbjct 2320 TQAVLSGVQAGVNHGLQQQSADPNNGIGVSISLNHQQSKSETKYQHDIVSGSTLSAGNNV 2379
Query 1268 SVDISGKNIFIESKEKNPANNIDIYSGKFIANGGQVSILSGGNINLYTVQESSSSNEDIT 1327
SV +GKN K+ N + ++ + +G I +G S+ + +I L ++ + +
Sbjct 2380 SVTATGKN-----KDHNNSGDM-LITGSQIKSGNDTSLNAQNDILLAAAADTRQTTGKNS 2433
Query 1328 KKSSFSGIKYNTSKTNATRNQISELPGILKADYIGIKADNDVRLVGTEFEYLQAAKIQAG 1387
K G+ + TN +S GI ++ G + N T + + + +G
Sbjct 2434 SKGGGVGVSFGGG-TNG--GGLSIFAGINGSE--GREKGNGTTWTETTLDAGKNVSLTSG 2488
Query 1388 RNLSLLTASTTVTETLKKDKNSVVWQSMQDKGSVTETAQLPRFNGPTPPEFKAAGGLIVQ 1447
R+ +L A + + N++ S+QD ++ Q G + +G
Sbjct 2489 RDTTLSGAQVSGEKVTADVGNNLTISSLQDSDRY-DSRQNRVAAGGSFTFGSMSGSGYAS 2547
Query 1448 IPIGEKDQNKIEIRDQILILANQPGNEYL-------------------KQLVNRNDVDWQ 1488
I + N +R+Q I A + G + K +N N + W
Sbjct 2548 ISQDKIKSNYDSVREQSGIYAGKDGFDVTVGNHTQLNGAVIASTATDDKNSLNTNTLGWS 2607
Query 1489 KVILAQKDWDYKSQGLT---GAGAAIIAIIVVMVTAGAGSAVVGALGGS--------ATT 1537
I Q D+ G++ G+G + ++ AGA +A+ G G S +
Sbjct 2608 D-IHNQADYKASHTGISLSGGSGMSASQMVASNAIAGAANALTGMSGSSGHAEGTTSSAI 2666
Query 1538 LGGSAVVMTQAAVTSLATQASVSLINNGGDLG------KTLKDLGSKDSVKNLAAS---- 1587
GG+ ++ + + S N G + K K L + ++
Sbjct 2667 SGGNLIIRNKESQKQDIAGLSRDPENANGSIAPIFDREKEQKRLQEAQVISQISGQMSNI 2726
Query 1588 VVTAGLLSQVGSALNLKPDTSGFSARLLNNFTTAV-----GST---LVQ--TAIKGGDLE 1637
V+T G + +A P S R + + GST +VQ T + GG
Sbjct 2727 VMTYGETEAMKAARKEHPGMSDAQLRETPEYREVMKGYGTGSTPQMVVQAITGVLGGLNA 2786
Query 1638 DNLKVALLAGLAGAMQGELASQIGTHLDKVDPNVFEYAIHKIAHAAVGCAVAAATKSSCE 1697
N L GL A+ + G D + N+ +AHA G A ++
Sbjct 2787 GNPGQVLAGGLNPAVAQLIKQATG---DNREANL-------MAHAVWGALAAQLGGNNAA 2836
Query 1698 AGAIGAGVGEIVASLMPDPVNG---IEYNEDEKTKIRNTGKIVAGVVSAYAGYDVNTAAN 1754
+GA GA GE+ A + D G +E E+ +I I +G+ G + A
Sbjct 2837 SGAAGAFSGELAARYIIDNYYGGRTDNLSEQERQQISMLATIASGIAGGLVGNSTSAAGT 2896
Query 1755 SADI---AIQNNSLVKL-ATSTG-----KILVKTLDEFNALRKAGK----------QVTK 1795
A +++NN++ L TG + ++ N K GK +
Sbjct 2897 GAQAGRNSVENNAMSGLEGFGTGFQSYVQAQEALVNNTNLTDKNGKVLNPATPEEIKYAS 2956
Query 1796 DDLVTSFKKQGADELIGIADDLLTVFGRSSSSFDRALAAIDL----IVGTDLKPGKGESL 1851
D LVT +G D G LL +G +S F L A + ++G L G +++
Sbjct 2957 DKLVTGSIPEGQDPARG----LLISWGAGASVFGGELIAPAVGTVAVIGGTLLGGTTDAV 3012
Query 1852 K 1852
K
Sbjct 3013 K 3013
Score = 55.8 bits (133), Expect = 8e-10
Identities = 168/810 (21%), Positives = 309/810 (38%), Gaps = 125/810 (15%)
Query 77 NSANAGNRPVIG-VGQNSQGQNVPVVNIQTPTNGVSHNIYKQMDVLPEGVVLNNSRTGAN 135
N+ A N IG +G S + V++++ T +S+ + + G N +G +
Sbjct 1866 NAGGALNLKAIGDIGNISSVISGKTVSLESATGNISNLTRTEQWAMNNGY---NHFSGTD 1922
Query 136 SSLVGTVGANPFLAKGEARIILNEVNSSVASRFEGNLEVAGQRADVIIANPAGINIKGGG 195
+ + V A L G A G++ + G ++ + + G
Sbjct 1923 TGPLAAVRATDSLFMGAA----------------GDISITG----AAVSAGDSVLLAAGN 1962
Query 196 FINANKAILTTGKPQLNADGSIQQFVVDQGKITISANSGSSLGLGGNKNNADYVDLYARA 255
+N N AI + + G + V T++A + L G + N+ +
Sbjct 1963 DLNMN-AIQAGERRRYGGSGWYETHAVAP---TVTAGNSLMLSAGRDVNSQAAGITAENS 2018
Query 256 LELNAQLYANKDIQAITGANNISADLQQISTRTGT---GTTPTLAIDVKNLGGMYANNIY 312
+++ A N ++ TGA + + + GT T D+ G ++
Sbjct 2019 MDIRAGRDVNMAAES-TGAGDHDSTFSMKTVHDSVRQQGTDMTSGGDITVTAGRDITSVA 2077
Query 313 LLGNEKGLGVSNAGTIRAVNNLVVTSAGKIEHKGSLESTSNTQGLVSIQTTQTGDNGNIN 372
KG NAG +++V+ +A + ++ S ES L+S QTT+T ++
Sbjct 2078 TAVTAKGDIRVNAG-----HDIVLGTATESDYHYS-ESGETRNRLLSHQTTRTITEDSVT 2131
Query 373 -SSGSITSKSMLSIDAANHLNITGNQVIVNQGVVSPLLLSAQGDINV------SNGAIIK 425
GS+ S + ++++A N+L + G+ V+ ++ V L+A ++V K
Sbjct 2132 REKGSLLSGNRVTVNAGNNLTVQGSDVVADRDV----SLAADNHVDVLAATSTDTSWRFK 2187
Query 426 NVQTGGDIYLDAQNINVGEN-----------TQIANVGLVNLNAA-AAIDIKKSARVKAV 473
+T G G + TQ + + A +I K A +
Sbjct 2188 ETKTSGLTGTGGIGFTTGSSKTTHDRREAGTTQSQSASTIGSTAGNVSITAGKQAH---I 2244
Query 474 NDLNIIAKQGLSVADANLVAEKGN---------MNLQSNSNITLQGTTLDLTKDLNINGT 524
+ ++IA + +S+ ++V + G+ +S + L G +
Sbjct 2245 SGSDVIANRDISITGDSVVVDPGHDRRTVDEKFEQKKSGLTVALSGAVGSAINNAVTMAR 2304
Query 525 GNVNLSSLNFSLLNGSSTLQNINAYSGLNL-VWDQTAKALPQISGNVTLEAANLIDLKGS 583
S + L G+ + + +G+N + Q+A I +++L +
Sbjct 2305 EAKETSDSRLAALKGTQAVLS-GVQAGVNHGLQQQSADPNNGIGVSISL----------N 2353
Query 584 NLSGKGDLKLQGKALNVGADLTAGKSLNLTATQSDLILNKTLNAQGNIDIASLDGKL-NA 642
+ K + K Q ++ G+ L+AG ++++TAT NK N G++ I K N
Sbjct 2354 HQQSKSETKYQHDIVS-GSTLSAGNNVSVTATGK----NKDHNNSGDMLITGSQIKSGND 2408
Query 643 TGLNATSSQGKLSIFGAKDTVLTNSGTVKTTLKGNQGVNV---GTISTGNLTLQNTVLES 699
T LNA Q + + A DT T T K + KG GV V G + G L ++
Sbjct 2409 TSLNA---QNDILLAAAADTRQT---TGKNSSKGG-GVGVSFGGGTNGGGL----SIFAG 2457
Query 700 QNGAIVVTSEGQNTLTDSIITAKGNIELFAKDNLTLDGIKSSSQQHTALNSKKNIYINS- 758
NG+ T T++ + A N+ L + + TL G + S ++ TA + N+ I+S
Sbjct 2458 INGSEGREKGNGTTWTETTLDAGKNVSLTSGRDTTLSGAQVSGEKVTA-DVGNNLTISSL 2516
Query 759 -----------QAGTGDSVNFSSTKITELNSTGTLSLISDK-NQNLQNTRLTGGAILLEA 806
+ G S F S ++ +G S+ DK N + R G +
Sbjct 2517 QDSDRYDSRQNRVAAGGSFTFGS-----MSGSGYASISQDKIKSNYDSVREQSGIYAGKD 2571
Query 807 GGTLNTPKVIEFNATGSNLLKNDSKLNSLN 836
G + + N D K NSLN
Sbjct 2572 GFDVTVGNHTQLNGAVIASTATDDK-NSLN 2600
Score = 42.4 bits (98), Expect = 1e-05
Identities = 51/222 (23%), Positives = 95/222 (43%), Gaps = 19/222 (9%)
Query 1207 ATGITAANGDVRIEANKNILFDAAIEQSYDRSTTTEKKSSWGGLKKKYITTVSENNQANA 1266
AT +TA GD+R+ A +I+ A E Y S + E ++ L + T++E++
Sbjct 2077 ATAVTA-KGDIRVNAGHDIVLGTATESDYHYSESGETRNRL--LSHQTTRTITEDSVTRE 2133
Query 1267 ASVDISGKNIFIESKEKNPANNIDIYSGKFIANGGQVSILSGGNINLYTVQESSSSNEDI 1326
+SG + + N NN+ + +A+ VS+ + ++++ + +S
Sbjct 2134 KGSLLSGNRVTV-----NAGNNLTVQGSDVVAD-RDVSLAADNHVDVLAATSTDTSWRFK 2187
Query 1327 TKKSS----FSGIKYNT--SKTNATRNQISELPGILKADYIGIKADNDVRLVGTEFEYLQ 1380
K+S GI + T SKT R + A IG A N V + + ++
Sbjct 2188 ETKTSGLTGTGGIGFTTGSSKTTHDRREAGTTQS-QSASTIGSTAGN-VSITAGKQAHIS 2245
Query 1381 AAKIQAGRNLSLLTASTTVTETLKKDKNSVVWQSMQDKGSVT 1422
+ + A R++S+ S V D+ +V + Q K +T
Sbjct 2246 GSDVIANRDISITGDSVVVDP--GHDRRTVDEKFEQKKSGLT 2285
Score = 35.0 bits (79), Expect = 0.002
Identities = 54/235 (23%), Positives = 94/235 (40%), Gaps = 32/235 (14%)
Query 1184 INGDKGVTIRATGNSNQDNLVLQATGITAANGDVRIEANKNILFDAAIEQSYDRSTTTEK 1243
+ G G+T+ + NLVL ++G NG + A +N + A Q ++++
Sbjct 319 VTGTTGLTLNQSRLVTDKNLVLSSSGQIVQNGG-ELTAGQNAMLSA---QHLNQTS---- 370
Query 1244 KSSWGGLKKKYITTVSENNQANAASVDISGKNIFIESKEKNPANNIDIYSGKFIANGGQV 1303
G + T++ + ++GK + + S N +G + G
Sbjct 371 ----GTVNAAENVTLTTTDDTTLKGRSVAGKTLTVSSGSLN--------NGGTLVAGRDA 418
Query 1304 SILSGGNINLYTVQES--SSSNEDITKKSSF-SGIKYNTSKTNATRNQISELPGILKADY 1360
++ +G N TVQ + + D+T S SG + S NAT +S G
Sbjct 419 TVKTGTFSNTGTVQGNGLKVTATDLTSTGSIKSGSTLDISARNAT---LSGDAGAKDRAL 475
Query 1361 IGIKA--DNDVRLVGTEFEYLQAAKIQAGRNLS----LLTASTTVTETLKKDKNS 1409
+ + +N RLV + L A +I LS L+ ++ T+T T K NS
Sbjct 476 VTVSGTLENRGRLVSDDVLTLSATQINNSGTLSGAKELVASADTLTTTEKSVTNS 530
Score = 28.1 bits (61), Expect = 0.21
Identities = 36/149 (24%), Positives = 65/149 (44%), Gaps = 12/149 (8%)
Query 1498 DYKSQGLTGAGAAIIAIIVVMVTAGAGSAVVGALGGSATTLGGSAVVMTQAAVTSLATQA 1557
D SQG T AA +++AG S +L S T+ G+ V + Q VT+ T
Sbjct 796 DIMSQGDTTLNAATTDNRGSLLSAGTLSLDGNSLDNSG-TVQGNHVTIRQNGVTNSGTLT 854
Query 1558 SVSLINNGGDLGKTLKDLGSKDSVKNLAASVVTAGLLSQVGSALNLKPDTSGFSARLLNN 1617
++ + L + + ++ N S++T+G L+ +L + + + ++
Sbjct 855 GIAALT----LAARMDMASPQPALMNNGGSLLTSGDLTITAGSL-----ANSGAIQAADS 905
Query 1618 FTTAVGSTLVQTAIKGGDLEDNLKVALLA 1646
T + LV TA G + N ++AL A
Sbjct 906 LTARLTGELVSTA--GSKVTSNGEMALSA 932
Score = 25.4 bits (54), Expect = 1.4
Identities = 26/106 (25%), Positives = 43/106 (41%), Gaps = 7/106 (7%)
Query 1519 VTAGAGSAVVGALGGSATTLGGSAVVMTQAAVTSLATQASVSLINNGGDLGKTLKDLGSK 1578
+ AG + V + T+ G+ + +T +TS + S S ++ D G+K
Sbjct 412 LVAGRDATVKTGTFSNTGTVQGNGLKVTATDLTSTGSIKSGSTLDISARNATLSGDAGAK 471
Query 1579 DSVKNLAASVVTAGLLSQVGSALNLKPDTSGFSARLLNNFTTAVGS 1624
D A V +G L G ++ D SA +NN T G+
Sbjct 472 D-----RALVTVSGTLENRGRLVS--DDVLTLSATQINNSGTLSGA 510
Score = 25.0 bits (53), Expect = 1.8
Identities = 31/150 (21%), Positives = 61/150 (41%), Gaps = 14/150 (9%)
Query 1257 TVSENNQANAASVDISGKNIFIESKEKNPANNIDIYSGKFIANGGQVSILSGGNINLYTV 1316
T+ + + +V ++G NI N N++ + I N I +GG +NL +
Sbjct 1817 TLHNGSVISGNNVQLAGGNITNSGSSINAQNDLLLDRTGSIDNLNAGLINAGGALNLKAI 1876
Query 1317 QESSSSNEDITKKS----SFSGIKYNTSKT-----NATRNQIS-----ELPGILKADYIG 1362
+ + + I+ K+ S +G N ++T N N S L + D +
Sbjct 1877 GDIGNISSVISGKTVSLESATGNISNLTRTEQWAMNNGYNHFSGTDTGPLAAVRATDSLF 1936
Query 1363 IKADNDVRLVGTEFEYLQAAKIQAGRNLSL 1392
+ A D+ + G + + AG +L++
Sbjct 1937 MGAAGDISITGAAVSAGDSVLLAAGNDLNM 1966
Score = 23.1 bits (48), Expect = 6.8
Identities = 21/83 (25%), Positives = 34/83 (41%), Gaps = 12/83 (14%)
Query 1198 SNQDNLVLQATGITAANGDVRIEANKNILFDAAIEQSYDRSTTTEKKSSWGGLKK----K 1253
S LV A +T V ++ N++ D+A S+T ++S GG
Sbjct 508 SGAKELVASADTLTTTEKSVT-NSDGNLMLDSA-------SSTLAGETSAGGTVSVKGNS 559
Query 1254 YITTVSENNQANAASVDISGKNI 1276
TT + Q N+ SVD+ +
Sbjct 560 LKTTTTAQTQGNSVSVDVQNAQL 582
Score = 23.1 bits (48), Expect = 6.8
Identities = 23/92 (25%), Positives = 38/92 (41%), Gaps = 8/92 (9%)
Query 1508 GAAIIAIIVVMVTAGAGSAVVGALGGSATTLGGSAVVMTQAAVTSLATQASVSLINNGGD 1567
GAA+ A V++ AG + G GGS T AV T + +++ G D
Sbjct 1947 GAAVSAGDSVLLAAGNDLNMNAIQAGERRRYGGSGWYETH-AVAPTVTAGNSLMLSAGRD 2005
Query 1568 LGKTLKDLGSKDSVK-------NLAASVVTAG 1592
+ + +++S+ N+AA AG
Sbjct 2006 VNSQAAGITAENSMDIRAGRDVNMAAESTGAG 2037
Score = 23.1 bits (48), Expect = 6.8
Identities = 20/76 (26%), Positives = 32/76 (42%), Gaps = 3/76 (4%)
Query 73 IQADNSANAGNR-PVIGVGQNSQGQNVP--VVNIQTPTNGVSHNIYKQMDVLPEGVVLNN 129
I + ++ +AGN V G+N N ++ +G ++ Q D+L
Sbjct 2367 IVSGSTLSAGNNVSVTATGKNKDHNNSGDMLITGSQIKSGNDTSLNAQNDILLAAAADTR 2426
Query 130 SRTGANSSLVGTVGAN 145
TG NSS G VG +
Sbjct 2427 QTTGKNSSKGGGVGVS 2442
>B3BM48 tRNA nuclease CdiA [Escherichia coli O157:H7 (strain EC869)]
Length=3209
Score = 232 bits (592), Expect = 2e-63
Identities = 254/904 (28%), Positives = 400/904 (44%), Gaps = 146/904 (16%)
Query 56 LVASMSLWMPLAPVYAQIQADNSANAGNRPVIGVGQNSQGQNVPVVNIQTPTN-GVSHNI 114
LV+++ PL P + P G G + VPVVNI TP G+SHN
Sbjct 16 LVSAIIAGQPLLPAVGAVIT---------PQNGAGMDKAANGVPVVNIATPNGAGISHNR 66
Query 115 YKQMDVLPEGVVLNNSRTGAN-SSLVGTVGANPFL-AKGEARIILNEVNSSVASRFEGNL 172
+ +V EG++LNN+ N + L G + NP L A GEA+ I+NEV S +G
Sbjct 67 FTDYNVGKEGLILNNATGKLNPTQLGGLIQNNPNLKAGGEAKGIINEVTGGNRSLLQGYT 126
Query 173 EVAGQRADVIIANPAGINIKGGGFINANKAILTTGKPQLNADGSIQQFVVDQGKITISAN 232
EVAG+ A+V++ANP GI G GFIN A LTTG+P +NADGS+Q V +G ITI+
Sbjct 127 EVAGKAANVMVANPYGITCDGCGFINTPHATLTTGRPVMNADGSLQALEVTEGSITIN-- 184
Query 233 SGSSLGLGGNKNNADYVDLYARALELNAQLYANKDIQAITGANNISADLQQISTRTGTGT 292
G G + +D V + ARA E+NA L+A KD+ GAN I+AD ++S G G
Sbjct 185 -----GAGLDGTRSDAVSIIARATEVNAALHA-KDLTVTAGANRITAD-GRVSALKGEGD 237
Query 293 TPTLAIDVKNLGGMYANNIYLLGNEKGLGVSNAGTIRAVNNLVVTSAGKIEHKGSLESTS 352
P +A+D LGGMYA I+L E G+GV+ ++++ SAGK+ K SL +
Sbjct 238 VPKVAVDTGALGGMYARRIHLTSTESGVGVNLGNLYAREGDIILNSAGKLVLKNSLAGGN 297
Query 353 NTQGLVSIQTTQTGDNGNINSSGSITSKSMLSIDAANHLNITGNQVIVNQGVVSPLLLSA 412
TT TG +++ SG + LS+ L + ++++ ++ L+LS+
Sbjct 298 ---------TTVTGT--DVSLSGDNKAGGNLSVTGTTGLTLNQSRLVTDKN----LVLSS 342
Query 413 QGDINVSNGAIIKNVQTGGDIYLDAQNINVGENTQIANVGLVNLNAAAAIDIKKSARVKA 472
G I V NG + G + L AQ++N T +NAA ++ +
Sbjct 343 SGQI-VQNGG---ELTAGQNAMLSAQHLNQTSGT---------VNAA------ENVTLTT 383
Query 473 VNDLNIIAKQGLSVADANLVAEKGNMNLQSNSNITLQGTTLDLTKDLNINGTGNVNLSSL 532
+D + +G S+A L G++N G TL +D +
Sbjct 384 TDDTTL---KGRSIAGKTLTVSSGSLN---------NGGTLVAGRDATVK---------- 421
Query 533 NFSLLNGSSTLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANLIDLKGSNLSGKGDLK 592
+ T N G L T ++ ++++ + +D+ N + GD
Sbjct 422 -------TGTFSNTGTVQGNGLKVTAT-----DLTSTGSIKSGSTLDISARNATLSGDAG 469
Query 593 LQGKA-------LNVGADLTAGKSLNLTATQSDLILNKTLNAQGNIDIASLDGKLNATGL 645
+ A L L + L L+ATQ +N + G ++ + L T
Sbjct 470 AKDSARVTVSGTLENRGRLVSDDVLTLSATQ----INNSGTLSGAKELVASADTLTTTEK 525
Query 646 NATSSQGKLSIFGAKDTVL--TNSGTVKTTLKGNQGVNVGTIST-GN---LTLQNTVLE- 698
+ T S G L + A T+ T++G+ ++KGN T T GN + +QN L+
Sbjct 526 SVTHSDGNLMLNSASSTLAGETSAGST-VSVKGNSLKTTATAQTQGNSVSVDVQNAQLDG 584
Query 699 SQNGAIVVTSEGQNTLTDSIITAKGNIELFAKDNLTLDGIKSSSQQHTALNSKKNIYINS 758
+Q ++T LT S ++ ++ L A + LT G+ S ALN++ NS
Sbjct 585 TQAARDILTLNASEKLTHSGKSSAPSLSLSAPE-LTSSGVLVGS----ALNTQSQTLTNS 639
Query 759 QAGTGDSVNFSSTKITELNSTGTLSLISDKNQNLQNTRLTGGAILLEAGGTLNTPKVIEF 818
G + +T+ + GTL +D ++ + R G I + G TLNT +
Sbjct 640 GLLQGKASLTVNTQRLDNQQNGTLYSAADLTLDIPDIR-NSGLITGDNGLTLNTASLSNP 698
Query 819 NATGSNLLKNDSKLNSLNGDLSIQ-------TKESLTIDPNIHTLKAIGDIELASK---- 867
++ L + + +L+GD +Q ++L+ N L A GD+ L K
Sbjct 699 GKIIADTL--NVRATTLDGDGLLQGAGALALAGDTLSQGRNGRWLTA-GDLSLRGKTLHT 755
Query 868 ----QGTLILAGYGGQAGNGS---------EKVLNLTTTG-----GGISLEGASVELQGA 909
QG + A +GS LT+TG G +L A+ + +G+
Sbjct 756 AGTTQGQNLTVQADNWANSGSVLATGNLTASATGQLTSTGDIMSQGDTTLNAATTDNRGS 815
Query 910 QLNA 913
L+A
Sbjct 816 LLSA 819
Score = 86.7 bits (213), Expect = 4e-19
Identities = 210/937 (22%), Positives = 363/937 (39%), Gaps = 161/937 (17%)
Query 72 QIQADNSANA----GNRPVIGVGQNSQG-QNVPVVNIQTPTNGVSHNI----YKQMDVLP 122
+I AD +A G+ P + V + G +++ + +GV N+ ++ D++
Sbjct 222 RITADGRVSALKGEGDVPKVAVDTGALGGMYARRIHLTSTESGVGVNLGNLYAREGDIIL 281
Query 123 EG---VVLNNSRTGANSSLVGTVGANPFLAKGEARIILNEVNSSVASRFEGNLEVAGQRA 179
+VL NS G N+++ GT +V+ S ++ GNL V G
Sbjct 282 NSAGKLVLKNSLAGGNTTVTGT-----------------DVSLSGDNKAGGNLSVTGTTG 324
Query 180 DVI----IANPAGINIKGGGFINANKAILTTGKPQLNADGSIQQFVVDQGKITISAN--- 232
+ + + + G I N LT G+ NA S Q G + + N
Sbjct 325 LTLNQSRLVTDKNLVLSSSGQIVQNGGELTAGQ---NAMLSAQHLNQTSGTVNAAENVTL 381
Query 233 -SGSSLGLGGNKNNADYVDLYARALELNAQLYANKDIQAITGANNISADLQQISTR-TGT 290
+ L G + + + +L L A +D TG + + +Q + T T
Sbjct 382 TTTDDTTLKGRSIAGKTLTVSSGSLNNGGTLVAGRDATVKTGTFSNTGTVQGNGLKVTAT 441
Query 291 GTTPTLAIDVKNLGGMYANNIYLLGNEKGLGVSNAGTIRAVNNLVVTSAGKIEHKGSLES 350
T T +I + + A N L G+ AG A ++ VT +G +E++G L S
Sbjct 442 DLTSTGSIKSGSTLDISARNATLSGD--------AG---AKDSARVTVSGTLENRGRLVS 490
Query 351 TSNTQGLVSIQTTQTGDNGNINSSGS-ITSKSMLSIDAANHLNITGNQVIVNQGVVSPLL 409
++++ TQ ++G ++ + + S L+ + + GN ++ +
Sbjct 491 DD----VLTLSATQINNSGTLSGAKELVASADTLTTTEKSVTHSDGNLMLNSASSTLAGE 546
Query 410 LSAQGDINVSNGAI--IKNVQT-GGDIYLDAQNINVGENTQIANVGLVNLNAAAAIDIK- 465
SA ++V ++ QT G + +D QN + + TQ A ++ LNA+ +
Sbjct 547 TSAGSTVSVKGNSLKTTATAQTQGNSVSVDVQNAQL-DGTQAAR-DILTLNASEKLTHSG 604
Query 466 KSARVKAVNDLNIIAKQGLSVADANLVAEKGNMN---LQSNSNITLQGTTLDLTKDLNIN 522
KS+ + G+ V A + N LQ +++T+ LD ++ +
Sbjct 605 KSSAPSLSLSAPELTSSGVLVGSALNTQSQTLTNSGLLQGKASLTVNTQRLDNQQNGTLY 664
Query 523 GTGNVNLSS---LNFSLLNGSS--TLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANL 577
++ L N L+ G + TL + + ++ D + G+ L+ A
Sbjct 665 SAADLTLDIPDIRNSGLITGDNGLTLNTASLSNPGKIIADTLNVRATTLDGDGLLQGAGA 724
Query 578 IDLKGSNLSG--------KGDLKLQGKALNVGADLTAGKSLNLTATQSDLILNKTLNAQG 629
+ L G LS GDL L+GK L+ A T G+ NLT + + ++ A G
Sbjct 725 LALAGDTLSQGRNGRWLTAGDLSLRGKTLHT-AGTTQGQ--NLTVQADNWANSGSVLATG 781
Query 630 NIDIASLDGKLNATG---------LNATSSQGKLSIFGA-----KDTVLTNSGTVK---T 672
N+ AS G+L +TG LNA ++ + S+ A L N GTV+
Sbjct 782 NLT-ASATGQLTSTGDIMSQGDTTLNAATTDNRGSLLSAGTLSLDGNSLDNRGTVQGDHV 840
Query 673 TLKGNQGVNVGTIS-TGNLTLQNTVLESQ-----NGAIVVTSEGQNTLTDSIITAKGNIE 726
T++ N N GT + LTL ++ Q NG ++TS G T+T IT+ G+ +
Sbjct 841 TIRQNSVTNSGTFTGIAALTLAARMVSPQPALMNNGGSLLTS-GDLTITAGSITSSGHWQ 899
Query 727 ----LFAKDNLTLDGIKSSSQQHTALNSKKNIYINSQAGTGDSVNFSSTKITELNSTGTL 782
L D+L G ++ TA TG+ V+ + +K+T
Sbjct 900 GKRVLITADSLANSGAIQAADSLTARL------------TGELVSAAGSKVT-------- 939
Query 783 SLISDKNQNLQNTRLTGGAILLEAGGTLNTPKVIEFNATGSNLLKNDSKLNSLNGDLSIQ 842
+ G + L A N+ + I N T K NSL I
Sbjct 940 ---------------SNGEMALSALNLSNSGQWIAKNLT--------LKANSLTSAGDIT 976
Query 843 TKESLTIDPNIHTLKAIGDIELASKQGTLIL-----AGYGGQAGNGSEKVLNLTTTGGGI 897
++LT+ N TL +L S G L L G GN + T GG +
Sbjct 977 GVDALTLTVN-QTLNNHASGKLLSA-GVLTLKADSVTNDGQLQGNATTITAGQLTNGGHL 1034
Query 898 SLEGASVELQGAQLNAEKNIKILANNENIQIISIKNK 934
E ++ G N + + N N+ ++ N+
Sbjct 1035 QGETLTLTASGGVNNRSGGVLMSRNALNVSTATLSNQ 1071
Score = 75.9 bits (185), Expect = 7e-16
Identities = 151/734 (21%), Positives = 286/734 (39%), Gaps = 125/734 (17%)
Query 298 IDVKNLGGMYANNIYLLGNEKGLGVSNAGTIRAVNNLVVTSAGKIEHKGSLESTSNTQGL 357
I + N + NN+ L G G ++ G+I A N+L++ S G I++ + N G
Sbjct 1832 ITLHNGSVISGNNVQLAG---GNITNSGGSINAQNDLLLDSTGSIDNLNA--GLINAGGA 1886
Query 358 VSIQTTQTGDNGNINSSGSITSKSMLSIDAA-------------------NHLNITGNQV 398
++++ GD GNI+S + S +S+++A NH + T
Sbjct 1887 LNLKAI--GDIGNISS---VISGKTVSLESATGNISNLTRTEQWAMNNGYNHFSGTDTGP 1941
Query 399 IVNQGVVSPLLLSAQGDINVSNGAIIKN----VQTGGDIYLDAQNINVGENTQIANVGLV 454
+ L + A GDI+++ A+ + G D+ ++A I GE + G
Sbjct 1942 LAAVRATDSLFMGAAGDISITGAAVSAGDSVLLSAGNDLNMNA--IQAGERRRYGGSGWY 1999
Query 455 NLNAAA-AIDIKKSARVKAVNDLN-----IIAKQGLSVA---DANLVAEK---------- 495
+A A + S + A D+N I+A+ + + D N+ AE
Sbjct 2000 ETHAVAPTVTAGNSLMLSAGRDVNSQAAGIMAENSMDIRAGRDVNMAAESTGTGDHDSTF 2059
Query 496 -------------------GNMNLQSNSNITLQGTTLDLTKDLNINGTGNVNLSSLNFSL 536
G++ + + +IT T + D+ +N ++ L + S
Sbjct 2060 SMKTVHDSVRQQGTDMTSGGDITVTAGRDITSVATAVTAKGDIRVNAGHDIVLGTATESD 2119
Query 537 LNGSSTLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANLIDLKGSNLSGKGDLKLQGK 596
+ S + + N L+ QT + + + S VT E KGS LSG G
Sbjct 2120 YHYSESGETRN-----RLLSHQTTRTITEDS--VTRE-------KGSLLSGNRVTVDAGD 2165
Query 597 ALNV-GADLTAGKSLNLTA-TQSDLILNKTLNAQGNIDIASLDGKLNATGLNATSSQGKL 654
L V G+D+ A + ++L A D++ + + G + G+ T K
Sbjct 2166 NLTVEGSDVVADRDVSLAAGNHVDVLAATSTDTSWRFKETKKSGLMGTGGIGFTIGSSKT 2225
Query 655 SIFGAKDTVLTNSGTVKT--TLKGNQGVNVGT---ISTGNLTLQNTVLESQNGAIVVTSE 709
+ ++ T S + T + GN + G IS ++ + + + +V
Sbjct 2226 T-HDRREAGTTQSQSASTIGSTAGNVSITAGKQAHISGSDVIANRDISITGDSVVVDPGH 2284
Query 710 GQNTLTDSIITAKGNIELFAKDNL----------TLDGIKSSSQQHTALNSKKNIYINSQ 759
+ T+ + K + + + + +SS + AL + K Q
Sbjct 2285 DRRTVDEKFEQKKSGLTVALSGTVGSAINNAVTSAQETKESSDSRLKALQATKTALSGVQ 2344
Query 760 AGTGDSVNFSSTKITELNSTG-TLSLISDKNQNLQNTRLTGGAILLEAGGTLNTPKVIEF 818
AG ++ +T + N+TG +LSL + K+++ Q++ +G TLN +
Sbjct 2345 AGQAAAM---ATATGDPNATGVSLSLTTQKSKSQQHSESD-----TVSGSTLNAGNNLSV 2396
Query 819 NATGSNLLKNDSKLNSLNGDLSIQTKESLTIDPNIHTLKAIGDIELASKQGTLILAGYGG 878
ATG N + D++ GD+ I + L N +L A D+ L+ T G
Sbjct 2397 VATGKN--RGDNR-----GDIVIAGSQ-LKAGGNT-SLDAANDVLLSGAANTQKTTGRNS 2447
Query 879 QAGNGSEKVLNLTTTGGGISLEGASVELQGAQL--NAEKNIKILANNENIQIISIKNKLN 936
+G G + G GIS+ + +G++ E + + + + I S ++ +
Sbjct 2448 SSGGGVGVSIGAGGNGAGISVFASVNAAKGSEKGNGTEWTETTIDSGKTVTINSGRDTVL 2507
Query 937 NSKLSDSNKLLVDL 950
N + N+++ D+
Sbjct 2508 NGAQVNGNRIIADV 2521
Score = 68.6 bits (166), Expect = 1e-13
Identities = 147/694 (21%), Positives = 280/694 (40%), Gaps = 124/694 (18%)
Query 202 AILTTGKPQLNADGSIQQF--VVDQGKITISA----NSGS-----SLGLGGNKNN----- 245
++L TG +A G + ++ QG T++A N GS +L L GN +
Sbjct 776 SVLATGNLTASATGQLTSTGDIMSQGDTTLNAATTDNRGSLLSAGTLSLDGNSLDNRGTV 835
Query 246 -ADYVDLYARALELNAQLYANKDIQAITGANNISADLQQISTRTGT----GTTPTLAIDV 300
D+V + ++ N+ + I A+T A + + + G+ G A +
Sbjct 836 QGDHVTIRQNSVT-NSGTFTG--IAALTLAARMVSPQPALMNNGGSLLTSGDLTITAGSI 892
Query 301 KNLGGMYANNIYLLGNEKGLGVSNAGTIRAVNNLVVTSAGKIEHKGSLESTSNTQGLVSI 360
+ G + + + ++N+G I+A ++L G++ + TSN G +++
Sbjct 893 TSSGHWQGKRVLITADS----LANSGAIQAADSLTARLTGELVSAAGSKVTSN--GEMAL 946
Query 361 QTTQTGDNGN-INSSGSITSKSMLS---IDAANHLNITGNQVIVNQGVVSPLLLSAQGDI 416
++G I + ++ + S+ S I + L +T NQ + N S LLSA G +
Sbjct 947 SALNLSNSGQWIAKNLTLKANSLTSAGDITGVDALTLTVNQTLNNH--ASGKLLSA-GVL 1003
Query 417 NVSNGAIIKNVQTGGDIYLDAQNINVGENTQIANV--GLVNLNAAAAIDIKKSARVKAVN 474
+ ++ + Q G +A I G+ T ++ + L A+ ++ + + + N
Sbjct 1004 TLKADSVTNDGQLQG----NATTITAGQLTNGGHLQGETLTLTASGGVNNRSGGVLMSRN 1059
Query 475 DLNI----IAKQGLSVADANLVAEKGNMNLQSNSNITLQGTTLDLTKDLNIN-GTGNVNL 529
LN+ ++ QG ++ V+ LQ++ I L G+ L LT + N G+G V
Sbjct 1060 ALNVSTATLSNQG-TIQGGGGVSLNATDRLQNDGKI-LSGSNLTLTAQVLANTGSGLVQA 1117
Query 530 SSLNFSLLNGSSTLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANLIDLKGSNLSGKG 589
++L ++N ++G L A D+KG+ L+ G
Sbjct 1118 ATLLLDVVN--------------------------TVNGGRVL-ATGSADVKGTTLNNTG 1150
Query 590 DLKLQGKALNVGADLTAGKSLNLTATQSDLILNKTLNAQGNIDIASLDGKLNATG---LN 646
L+ GADL + + + L+ L +G+ + + G+L + G L+
Sbjct 1151 TLQ--------GADLLV--NYHTFSNSGTLLGTSGLGVKGSSLLQNGTGRLYSAGNLLLD 1200
Query 647 ATSSQGKLSIFGAKDTVLTNSGTVKTTLKGNQGVNVGTISTG---NLTLQNTVLES--QN 701
A G+ + D L + N GT++ G ++T QN +
Sbjct 1201 AQDFSGQGQVVATGDVTLKLIAAL---------TNHGTLAAGKTLSVTSQNAITNGGVMQ 1251
Query 702 GAIVVTSEGQNTLTDSIITAKGNIELFAKDNLTLDGIKS-SSQQHTALNSKKNIYINSQA 760
G +V G+ + ++TA +F+ L L+ S + +LNS+ +I I+
Sbjct 1252 GDAMVLGAGEAFTNNGMLTAGKGNSVFSAQRLFLNAPGSLQAGGDVSLNSRSDITISGFT 1311
Query 761 GTGDSVNFSSTKITELNST-----GTLSLISDKNQNLQNTRLTGGAILL--EAGGTLNTP 813
GT S+ + T LNS L L +D+ N L G ++ + ++ GT N
Sbjct 1312 GTAGSLTMNVAG-TLLNSALIYAGNNLKLFTDRLHNQHGDILAGNSLWVQKDSSGTAN-- 1368
Query 814 KVIEFNATGSNLLKNDSKLNSLNGDLSIQTKESL 847
S ++ + + GD+++ T L
Sbjct 1369 ---------SEIINRSGNIETTRGDITMNTAHLL 1393
Score = 66.6 bits (161), Expect = 4e-13
Identities = 128/622 (21%), Positives = 242/622 (39%), Gaps = 129/622 (21%)
Query 399 IVNQGVVSPLLLSAQGDINVSNGAIIK--NVQ-TGGDIYLDAQNINVGENTQIANVGLVN 455
I Q V+ P L + DI + NG++I NVQ GG+I +IN + + + G ++
Sbjct 1815 INGQTVMVPKLYLSPEDITLHNGSVISGNNVQLAGGNITNSGGSINAQNDLLLDSTGSID 1874
Query 456 LNAAAAIDIKKSARVKAVNDLNIIAKQGLSVADANLVAEKGNMN--------LQSNSNIT 507
A I+ + +KA+ D+ I+ +S +L + GN++ +N
Sbjct 1875 NLNAGLINAGGALNLKAIGDIGNISSV-ISGKTVSLESATGNISNLTRTEQWAMNNGYNH 1933
Query 508 LQGT------TLDLTKDLNINGTGNVNLS----SLNFSLLNGSSTLQNINA--------Y 549
GT + T L + G+++++ S S+L + N+NA Y
Sbjct 1934 FSGTDTGPLAAVRATDSLFMGAAGDISITGAAVSAGDSVLLSAGNDLNMNAIQAGERRRY 1993
Query 550 SGLNLVWDQTAKALPQISG--NVTLEAANLIDLKGSNLSGKGDLKLQGKALNVGADLTAG 607
G W +T P ++ ++ L A ++ + + + + + D+ AG
Sbjct 1994 GGSG--WYETHAVAPTVTAGNSLMLSAGRDVNSQAAGIMAENSM-----------DIRAG 2040
Query 608 KSLNLTATQSDLILNKTLNAQGNIDIASLDGKLNATGLNATSSQGKLSIFGAKDTVLTNS 667
+ +N+ A + T + + ++ + G + TS G +++ +D +T+
Sbjct 2041 RDVNMAAESTG-----TGDHDSTFSMKTVHDSVRQQGTDMTSG-GDITVTAGRD--ITSV 2092
Query 668 GTVKTTLKGNQGVNVGTISTGNLTLQNTVLESQNGAI---VVTSEGQNTLT-DSIITAKG 723
T T KG+ VN G ++ S++G +++ + T+T DS+ KG
Sbjct 2093 ATA-VTAKGDIRVNAGHDIVLGTATESDYHYSESGETRNRLLSHQTTRTITEDSVTREKG 2151
Query 724 N------IELFAKDNLTLDGIKSSSQQHTALNSKKNIYINSQAGTGDSVNFSSTKITELN 777
+ + + A DNLT++G + + +L + ++ + + T S F TK + L
Sbjct 2152 SLLSGNRVTVDAGDNLTVEGSDVVADRDVSLAAGNHVDVLAATSTDTSWRFKETKKSGLM 2211
Query 778 STGTLSLISDKNQNLQNTRLTGGAILLEAGGTLNTPKVIEFNATGSNLLKNDSKLNSLNG 837
TG + ++ + R GT + +T N+ K ++G
Sbjct 2212 GTGGIGFTIGSSKTTHDRR---------EAGTTQSQSASTIGSTAGNVSITAGKQAHISG 2262
Query 838 -------DLSIQTKESLTIDPNIHTLKAIGDIELASKQG-TLILAGYGGQAGNGSE---- 885
D+SI T +S+ +DP H + + + K G T+ L+G G A N +
Sbjct 2263 SDVIANRDISI-TGDSVVVDPG-HDRRTVDEKFEQKKSGLTVALSGTVGSAINNAVTSAQ 2320
Query 886 ----------KVLNLTTTG----------------GGISLEGASVEL------------- 906
K L T T G + G S+ L
Sbjct 2321 ETKESSDSRLKALQATKTALSGVQAGQAAAMATATGDPNATGVSLSLTTQKSKSQQHSES 2380
Query 907 ---QGAQLNAEKNIKILANNEN 925
G+ LNA N+ ++A +N
Sbjct 2381 DTVSGSTLNAGNNLSVVATGKN 2402
Score = 63.9 bits (154), Expect = 3e-12
Identities = 139/650 (21%), Positives = 252/650 (39%), Gaps = 129/650 (20%)
Query 323 SNAGTIRAVNNLVVTSAGKIEHKGSLESTSNTQGLVSIQTTQTGDNGNINSSGSITSKSM 382
+N+G++ A NL ++ G++ G + S QG ++ T + G++ S+G+++
Sbjct 772 ANSGSVLATGNLTASATGQLTSTGDIMS----QGDTTLNAATTDNRGSLLSAGTLSLDGN 827
Query 383 LSID-----AANHLNITGNQVIVNQGVVSPL--------LLSAQGDINVSNGAIIKNVQT 429
S+D +H+ I N V N G + + ++S Q + + G+++ T
Sbjct 828 -SLDNRGTVQGDHVTIRQNSV-TNSGTFTGIAALTLAARMVSPQPALMNNGGSLL----T 881
Query 430 GGDIYLDAQNINVGENTQIANVGLVNLNAAAAIDIKKSARVKAVNDLNIIAKQGLSVADA 489
GD+ + A +I + Q V + A + S ++A + L L A
Sbjct 882 SGDLTITAGSITSSGHWQGKRVLIT------ADSLANSGAIQAADSLTARLTGELVSAAG 935
Query 490 NLVAEKGNMNLQSNSNITLQGTTLDLTKDLNINGTGNVNLSSLNFSLLNGSSTLQNINAY 549
+ V G M L + LN++ +G +L N ++ +I
Sbjct 936 SKVTSNGEMALSA----------------LNLSNSGQWIAKNLTLKA-NSLTSAGDITGV 978
Query 550 SGLNLVWDQTAKALPQISGNVTLEAANLIDLKGSNLSGKGDLKLQGKALNVGADLTAGKS 609
L L +QT SG L +A ++ LK +++ G +LQG A + TAG+
Sbjct 979 DALTLTVNQTLNN--HASGK--LLSAGVLTLKADSVTNDG--QLQGNATTI----TAGQL 1028
Query 610 LNLTATQSDLILNKTLNAQGNIDIASLDGKLNATGLNATSSQGKLSIFGAKDTVLTNSGT 669
N Q + + TL A G ++ S ++ LN +++ L+N GT
Sbjct 1029 TNGGHLQGETL---TLTASGGVNNRSGGVLMSRNALNVSTA------------TLSNQGT 1073
Query 670 VKTTLKGNQGVNVGT----------ISTGNLTLQNTVLESQNGAIVVTS----EGQNTLT 715
++ G GV++ +S NLTL VL + +V + + NT+
Sbjct 1074 IQ----GGGGVSLNATDRLQNDGKILSGSNLTLTAQVLANTGSGLVQAATLLLDVVNTVN 1129
Query 716 DSIITAKGNIELFA---KDNLTLDGIKSSSQQHTALNSKKNIYINSQAGTGDSVNFSSTK 772
+ A G+ ++ + TL G HT NS + + G S+ + T
Sbjct 1130 GGRVLATGSADVKGTTLNNTGTLQGADLLVNYHTFSNSGTLLGTSGLGVKGSSLLQNGTG 1189
Query 773 ITELNSTGTLSLISDKNQNLQNTRLTGGAIL-----LEAGGTLNTPKVIEFNA----TGS 823
L S G L L + TG L L GTL K + + T
Sbjct 1190 --RLYSAGNLLLDAQDFSGQGQVVATGDVTLKLIAALTNHGTLAAGKTLSVTSQNAITNG 1247
Query 824 NLLKNDSKLNSL------NGDLSIQTKESLTIDPNIH-----TLKAIGDIELASKQGTLI 872
+++ D+ + NG L+ S+ + +L+A GD+ L S+ +
Sbjct 1248 GVMQGDAMVLGAGEAFTNNGMLTAGKGNSVFSAQRLFLNAPGSLQAGGDVSLNSRSD-IT 1306
Query 873 LAGYGGQAGNGSEKVLNLTTTGGGISLEGASVELQGAQLNAEKNIKILAN 922
++G+ G T G +++ A L A + A N+K+ +
Sbjct 1307 ISGFTG--------------TAGSLTMNVAGTLLNSALIYAGNNLKLFTD 1342
Score = 62.4 bits (150), Expect = 9e-12
Identities = 158/760 (21%), Positives = 273/760 (36%), Gaps = 151/760 (20%)
Query 1092 SSKLVSNSGSIDITSSKGISISGSELISKKGLVNIEALGALSQNYTSTIHGKDNKPKTLG 1151
+S + S +G++ IT+ K ISGS++I+ + + G
Sbjct 2240 ASTIGSTAGNVSITAGKQAHISGSDVIANRDI------------------------SITG 2275
Query 1152 ASIIIDGSQDFYDKGNENDQKYRFRTILKPTLINGDKGVTIRATGNSNQDNLVLQATGIT 1211
S+++D D + +QK T+ ++G G I S Q+ + +
Sbjct 2276 DSVVVDPGHDRRTVDEKFEQKKSGLTVA----LSGTVGSAINNAVTSAQETKESSDSRLK 2331
Query 1212 AANGDVRIEANKNILFDAAIEQSYDRSTTTEKKSSWGGLKKKYITTVSENNQANAASVDI 1271
A ++A K L Q+ +T T ++ G +TT +Q ++ S +
Sbjct 2332 A------LQATKTALSGVQAGQAAAMATATGDPNATG--VSLSLTTQKSKSQQHSESDTV 2383
Query 1272 SGK------NIFIESKEKNPANNIDIYSGKFIANGGQVSILSGGNINLYTVQE----SSS 1321
SG N+ + + KN +N G + G Q+ +GGN +L + ++
Sbjct 2384 SGSTLNAGNNLSVVATGKNRGDN----RGDIVIAGSQLK--AGGNTSLDAANDVLLSGAA 2437
Query 1322 SNEDITKKSSFSGIKYNTS-KTNATRNQISELPGILKADYIGIKADNDVRLVGTEFEYLQ 1380
+ + T ++S SG S IS + A G + N T + +
Sbjct 2438 NTQKTTGRNSSSGGGVGVSIGAGGNGAGISVFASVNAAK--GSEKGNGTEWTETTIDSGK 2495
Query 1381 AAKIQAGRNLSLLTASTTVTETLKKDKNSVVWQSMQDK------------------GSVT 1422
I +GR+ L A + + ++ S QD GS+T
Sbjct 2496 TVTINSGRDTVLNGAQVNGNRIIADVGHDLLISSQQDTSKYDSKQTSVAAGGSFTFGSMT 2555
Query 1423 ETAQLP--------RFNGPTPPEFKAAGGLIVQIPIGEKDQNKIEIRDQILILANQPGNE 1474
+ + RF+ AG I +G Q + ++ P
Sbjct 2556 GSGYIAASRDKMKSRFDSVAEQTGMFAGDGGFDITVGRHTQ----LDGAVIASTATPDKN 2611
Query 1475 YLKQ-LVNRNDVDWQKVILAQKDWDYKSQGLTGAGAAIIAIIVVMVTAGAGSAVVGALGG 1533
+L + +D+ + D+ G++ +G G G + G
Sbjct 2612 HLDTGTLGFSDLH------NEADYKVSHSGISLSGGGSF-----------GDKFQGNMPG 2654
Query 1534 SATTLGGS---AVVMTQAAVTSLATQASVSLINNGGDLGKTLKD-LGSKDSVKNL----- 1584
+ GG A TQAAV T N +L +D + + DS+ +
Sbjct 2655 GMISAGGHSGHAEGTTQAAVAE-GTITIRDRDNQKQNLANLSRDPVHANDSISPIFDKEK 2713
Query 1585 -AASVVTAGLLSQVGSALNLKPDTSGFSARLLNNFTTAVGSTLVQTAIK----------- 1632
+ T GL+S +GS + T G L A G TL A +
Sbjct 2714 EQRRLQTVGLISDIGSQVADIARTQG-ELNALKAAKEATGETLPANATEKQRQEYLAKLR 2772
Query 1633 --------------GGDLEDNLKVALLA--GLAGA-MQGELASQIGTHLDKVDPNVFEY- 1674
G +++ ++ A A GLAG + G LA L + + +Y
Sbjct 2773 DTQAYRNEMAKYGTGSEIQRGIQAATAALQGLAGGNLAGALAGASAPELAHLLKSTEKYP 2832
Query 1675 AIHKIAHAAVGCAVAAATKSSCEAGAIGAGVGEI----VASLMPDPVNGIEYNEDEKTKI 1730
A++ IAHA +G A AA ++ AGA GA GE+ +A ++ V + +E++K I
Sbjct 2833 AVNAIAHAILGGAAAAMQGNNVAAGAAGAATGELAARAIAGMLYPGVKQSDLSEEQKQTI 2892
Query 1731 RNTGKIVAGVVSAYAGYDVNTA---ANSADIAIQNNSLVK 1767
+ AG+ G +A A S A++NN L K
Sbjct 2893 STLATVSAGLAGGLTGNSTASAAVGAQSGKNAVENNYLSK 2932
Score = 57.4 bits (137), Expect = 3e-10
Identities = 145/705 (21%), Positives = 276/705 (39%), Gaps = 108/705 (15%)
Query 187 AGINI-KGGGFINANKAIL--TTGKPQ------LNADGSIQ-QFVVDQGKITISANSGSS 236
AG NI GG INA +L +TG +NA G++ + + D G I+ S SG +
Sbjct 1848 AGGNITNSGGSINAQNDLLLDSTGSIDNLNAGLINAGGALNLKAIGDIGNIS-SVISGKT 1906
Query 237 LGLG---GNKNNADYVDLYARALELNAQLYANKD---IQAITGANNISADLQQISTRTGT 290
+ L GN +N + +A N ++ D + A+ +++ + TG
Sbjct 1907 VSLESATGNISNLTRTEQWAMNNGYNH--FSGTDTGPLAAVRATDSLFMGAAGDISITGA 1964
Query 291 GTTPTLAIDVKNLGGMYANNIYLLGNEKGLGVSN-------AGTIRAVNNLVVTS----- 338
+ ++ + + G N G + G S A T+ A N+L++++
Sbjct 1965 AVSAGDSV-LLSAGNDLNMNAIQAGERRRYGGSGWYETHAVAPTVTAGNSLMLSAGRDVN 2023
Query 339 --AGKIEHKGSLESTSNTQGLVSIQTTQTGDNGNINSSGSI---TSKSMLSIDAANHLNI 393
A I + S++ + ++ ++T TGD+ + S ++ + + + + +
Sbjct 2024 SQAAGIMAENSMDIRAGRDVNMAAESTGTGDHDSTFSMKTVHDSVRQQGTDMTSGGDITV 2083
Query 394 TGNQVIVNQGVVSPLLLSAQGDINVSNGA-IIKNVQTGGDIYLDAQNINVGENTQIANVG 452
T + I + ++A+GDI V+ G I+ T D + E+ + N
Sbjct 2084 TAGRDITSVATA----VTAKGDIRVNAGHDIVLGTATESDYHYS-------ESGETRNRL 2132
Query 453 LVNLNAAAAID---IKKSARVKAVNDLNIIAKQGLSVADANLVAEKGNMNLQSNSNITLQ 509
L + + ++ + + N + + A L+V +++VA++ N L
Sbjct 2133 LSHQTTRTITEDSVTREKGSLLSGNRVTVDAGDNLTVEGSDVVADRDVSLAAGNHVDVLA 2192
Query 510 GTTLDL------TKDLNINGTGNVNLSSLNFSLLNGSSTLQNINAYSGLNLVWDQTAKAL 563
T+ D TK + GTG + + GSS + +G Q+A +
Sbjct 2193 ATSTDTSWRFKETKKSGLMGTGGIGFTI-------GSSKTTHDRREAGTTQ--SQSASTI 2243
Query 564 PQISGNVTLEAANLIDLKGSNLSGKGDLKLQGKALNV--GAD----------LTAGKSLN 611
+GNV++ A + GS++ D+ + G ++ V G D +G ++
Sbjct 2244 GSTAGNVSITAGKQAHISGSDVIANRDISITGDSVVVDPGHDRRTVDEKFEQKKSGLTVA 2303
Query 612 LTATQSDLILNKTLNAQGNIDIASLDGKLNA--------TGLNATSSQGKLSIFGAKDTV 663
L+ T I N +AQ + S D +L A +G+ A + + G +
Sbjct 2304 LSGTVGSAINNAVTSAQETKE--SSDSRLKALQATKTALSGVQAGQAAAMATATGDPNAT 2361
Query 664 LTNSGTVKTTLKGNQGVNVGTISTGNLTLQNTVLESQNGAIVVTSEGQNTLTDSIITAKG 723
+ K Q T+S L N + G + G + S + A G
Sbjct 2362 GVSLSLTTQKSKSQQHSESDTVSGSTLNAGNNLSVVATGKNRGDNRGDIVIAGSQLKAGG 2421
Query 724 NIELFAKDNLTLDGIKSSSQQHTALNSKKNIYINSQAGTGD---------SVNF------ 768
N L A +++ L G +++Q+ T NS + G G SVN
Sbjct 2422 NTSLDAANDVLLSG-AANTQKTTGRNSSSGGGVGVSIGAGGNGAGISVFASVNAAKGSEK 2480
Query 769 -SSTKITE--LNSTGTLSLISDKNQNLQNTRLTGGAILLEAGGTL 810
+ T+ TE ++S T+++ S ++ L ++ G I+ + G L
Sbjct 2481 GNGTEWTETTIDSGKTVTINSGRDTVLNGAQVNGNRIIADVGHDL 2525
Score = 52.8 bits (125), Expect = 7e-09
Identities = 142/713 (20%), Positives = 271/713 (38%), Gaps = 116/713 (16%)
Query 77 NSANAGNRPVIG-VGQNSQGQNVPVVNIQTPTNGVSHNIYKQMDVLPEGVVLNNSRTGAN 135
N+ A N IG +G S + V++++ T +S+ + + G N +G +
Sbjct 1882 NAGGALNLKAIGDIGNISSVISGKTVSLESATGNISNLTRTEQWAMNNGY---NHFSGTD 1938
Query 136 SSLVGTVGANPFLAKGEARIILNEVNSSVASRFEGNLEVAGQRADVIIANPAGINIKGGG 195
+ + V A L G A G++ + G ++ + + G
Sbjct 1939 TGPLAAVRATDSLFMGAA----------------GDISITG----AAVSAGDSVLLSAGN 1978
Query 196 FINANKAILTTGKPQLNADGSIQQFVVDQGKITISANSGSSLGLGGNKNNADYVDLYARA 255
+N N AI + + G + V T++A + L G + N+ + +
Sbjct 1979 DLNMN-AIQAGERRRYGGSGWYETHAVAP---TVTAGNSLMLSAGRDVNSQAAGIMAENS 2034
Query 256 LELNAQLYANKDIQAI-TGANNISADLQQISTRTGT-GTTPTLAIDVKNLGGMYANNIYL 313
+++ A N ++ TG ++ + ++ + GT T D+ G ++
Sbjct 2035 MDIRAGRDVNMAAESTGTGDHDSTFSMKTVHDSVRQQGTDMTSGGDITVTAGRDITSVAT 2094
Query 314 LGNEKGLGVSNAGTIRAVNNLVVTSAGKIEHKGSLESTSNTQGLVSIQTTQTGDNGNIN- 372
KG NAG +++V+ +A + ++ S ES L+S QTT+T ++
Sbjct 2095 AVTAKGDIRVNAG-----HDIVLGTATESDYHYS-ESGETRNRLLSHQTTRTITEDSVTR 2148
Query 373 SSGSITSKSMLSIDAANHLNITGNQVIVNQGVVSPLLLSAQGDINV------SNGAIIKN 426
GS+ S + +++DA ++L + G+ V+ ++ V L+A ++V K
Sbjct 2149 EKGSLLSGNRVTVDAGDNLTVEGSDVVADRDV----SLAAGNHVDVLAATSTDTSWRFKE 2204
Query 427 VQTGGDIYLDAQNINVGEN-----------TQIANVGLVNLNAA-AAIDIKKSARVKAVN 474
+ G + +G + TQ + + A +I K A ++
Sbjct 2205 TKKSGLMGTGGIGFTIGSSKTTHDRREAGTTQSQSASTIGSTAGNVSITAGKQAH---IS 2261
Query 475 DLNIIAKQGLSVADANLVAEKGNMNLQSNSNITLQGTTLDLTKDLNINGTGNVNLSSLNF 534
++IA + +S+ ++V + G+ T+D + +G ++
Sbjct 2262 GSDVIANRDISITGDSVVVDPGH-----------DRRTVDEKFEQKKSGLTVALSGTVGS 2310
Query 535 SLLNGSSTLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANLIDLKGSNLSGKGDLKLQ 594
++ N ++ Q S L Q K +SG +AA + G
Sbjct 2311 AINNAVTSAQETKESSDSRLKALQATKT--ALSGVQAGQAAAMATATG-----------D 2357
Query 595 GKALNVGADLTAGKSLNLTATQSDLILNKTLNAQGNIDIASLDGKLNATGLNATSSQGKL 654
A V LT KS + ++SD + TLNA N+ + ATG N ++G +
Sbjct 2358 PNATGVSLSLTTQKSKSQQHSESDTVSGSTLNAGNNLSVV-------ATGKNRGDNRGDI 2410
Query 655 SIFGAKDTVLTNSGTVKTTLKGNQGVNVGTISTGNLTLQNTVLESQNGAIVVTSEGQNTL 714
I G++ +G + N + G +T T +N+ S G + V+
Sbjct 2411 VIAGSQ----LKAGGNTSLDAANDVLLSGAANTQKTTGRNS---SSGGGVGVS------- 2456
Query 715 TDSIITAKGN---IELFAKDNLTLDGIKSSSQQ--HTALNSKKNIYINSQAGT 762
I A GN I +FA N K + + T ++S K + INS T
Sbjct 2457 ----IGAGGNGAGISVFASVNAAKGSEKGNGTEWTETTIDSGKTVTINSGRDT 2505
Score = 48.5 bits (114), Expect = 1e-07
Identities = 160/800 (20%), Positives = 287/800 (36%), Gaps = 128/800 (16%)
Query 1110 ISISGSELISKKGLVNIEALGALSQNYTSTIHGKDNKPKTLGASIIIDGSQDFYDKGNEN 1169
++ S ++S VN +A G +++N G+D ++ + + G ++
Sbjct 2008 VTAGNSLMLSAGRDVNSQAAGIMAENSMDIRAGRD-----------VNMAAESTGTG-DH 2055
Query 1170 DQKYRFRTILKPTLINGD---KGVTIRATGNSNQDNLVLQATGITAANGDVRIEANKNIL 1226
D + +T+ G G I T + ++ AT +TA GD+R+ A +I+
Sbjct 2056 DSTFSMKTVHDSVRQQGTDMTSGGDITVTAGRDITSV---ATAVTA-KGDIRVNAGHDIV 2111
Query 1227 FDAAIEQSYDRSTTTEKKSSWGGLKKKYITTVSENNQANAASVDISGKNIFIESKEKNPA 1286
A E Y S + E ++ L + T++E++ +SG + +++ +
Sbjct 2112 LGTATESDYHYSESGETRNRL--LSHQTTRTITEDSVTREKGSLLSGNRVTVDAGDNLTV 2169
Query 1287 NNIDIYSGKFIANGGQVSILSGGNINLYTVQESSSS-NEDITKKSSFS-----GIKYNTS 1340
D+ + + VS+ +G ++++ + +S TKKS G +S
Sbjct 2170 EGSDVVADR------DVSLAAGNHVDVLAATSTDTSWRFKETKKSGLMGTGGIGFTIGSS 2223
Query 1341 KTNATRNQISELPGILKADYIGIKADNDVRLVGTEFEYLQAAKIQAGRNLSLLTAST--- 1397
KT R + A IG A N V + + ++ + + A R++S+ S
Sbjct 2224 KTTHDRREAGTTQS-QSASTIGSTAGN-VSITAGKQAHISGSDVIANRDISITGDSVVVD 2281
Query 1398 ------TVTETLKKDK---------------NSVVWQSMQDKGS---------VTETAQL 1427
TV E ++ K N+ V + + K S T+TA
Sbjct 2282 PGHDRRTVDEKFEQKKSGLTVALSGTVGSAINNAVTSAQETKESSDSRLKALQATKTALS 2341
Query 1428 PRFNGPTPPEFKAAG-----GLIVQIPIGEKDQNKIEIRDQILILANQPGNEYLKQLVNR 1482
G A G G+ + + + + D + GN +
Sbjct 2342 GVQAGQAAAMATATGDPNATGVSLSLTTQKSKSQQHSESDTVSGSTLNAGNNLSVVATGK 2401
Query 1483 NDVDWQ-KVILAQKDWDYKSQGLTGAGAAIIAIIV----VMVTAGAGSAVVGALGGSATT 1537
N D + +++A K+ G T AA ++ T G S+ G +G S
Sbjct 2402 NRGDNRGDIVIAGS--QLKAGGNTSLDAANDVLLSGAANTQKTTGRNSSSGGGVGVSIGA 2459
Query 1538 LGGSAVVMTQAAVTSLATQASVSLINNGG-------DLGKTLKDLGSKDSVKNLAASVVT 1590
G A + A+V + A S NG D GKT+ +D+V N A V
Sbjct 2460 GGNGAGISVFASVNA----AKGSEKGNGTEWTETTIDSGKTVTINSGRDTVLN-GAQVNG 2514
Query 1591 AGLLSQVGSAL--NLKPDT-----------------------SGFSARLLNNFTTAVGST 1625
+++ VG L + + DT SG+ A + + S
Sbjct 2515 NRIIADVGHDLLISSQQDTSKYDSKQTSVAAGGSFTFGSMTGSGYIAASRDKMKSRFDSV 2574
Query 1626 LVQTAIKGGDLEDNLKVALLAGLAGAMQGELASQIGTHLDKVD---PNVFEYAIHKIAHA 1682
QT + GD ++ V L GA+ A+ HLD ++ A +K++H+
Sbjct 2575 AEQTGMFAGDGGFDITVGRHTQLDGAVIASTATPDKNHLDTGTLGFSDLHNEADYKVSHS 2634
Query 1683 AV----GCAVAAATKSSCEAGAIGAG--VGEIVASLMPDPVNGIEYNEDEKTKIRNTGKI 1736
+ G + + + G I AG G + G D + +N +
Sbjct 2635 GISLSGGGSFGDKFQGNMPGGMISAGGHSGHAEGTTQAAVAEGTITIRDRDNQKQNLANL 2694
Query 1737 VAGVVSAYAGYDVNTAANSADIAIQNNSLVKLATSTGKILVKTLDEFNALRKAGKQVTKD 1796
V A +Q L+ S + +T E NAL KA K+ T +
Sbjct 2695 SRDPVHANDSISPIFDKEKEQRRLQTVGLISDIGSQVADIARTQGELNAL-KAAKEATGE 2753
Query 1797 DL-VTSFKKQGADELIGIAD 1815
L + +KQ + L + D
Sbjct 2754 TLPANATEKQRQEYLAKLRD 2773
Score = 38.9 bits (89), Expect = 1e-04
Identities = 177/820 (22%), Positives = 297/820 (36%), Gaps = 152/820 (19%)
Query 557 DQTAKALPQISGNVTLEAANLIDLKGSNLSGKGDLKLQGKALNVGADLTAGKSLNLTATQ 616
D + +AL G++T+ A L + +S + +A V A L A K L +TA
Sbjct 168 DGSLQALEVTEGSITINGAGLDGTRSDAVS------IIARATEVNAALHA-KDLTVTAGA 220
Query 617 SDLILNKTLNAQGNIDIASLDGKLNATGLNATSSQGKLSIFGAKDTVLTNSGTVKTTLKG 676
+ + A G + +G + ++ G L A+ LT++ + G
Sbjct 221 N------RITADGRVSALKGEGDVPKVAVDT----GALGGMYARRIHLTSTESGVGVNLG 270
Query 677 NQGVNVGTI---STGNLTLQNTVLESQNGAIVVTSEGQNTLTDSIITAKGNIELFAKDNL 733
N G I S G L L+N++ + G T+T + ++ G+ + A NL
Sbjct 271 NLYAREGDIILNSAGKLVLKNSL-----------AGGNTTVTGTDVSLSGDNK--AGGNL 317
Query 734 TLDGIKSSSQQHTALNSKKNIYINSQAGTGDSVNFSSTKITELNSTGTLSLISDKNQNLQ 793
++ G + + L + KN+ ++S +G V EL + G +++S ++ N
Sbjct 318 SVTGTTGLTLNQSRLVTDKNLVLSS---SGQIVQNGG----ELTA-GQNAMLSAQHLN-- 367
Query 794 NTRLTGGAILLEAGGTLNTPKVIEFNATGSNLLKNDSKLNSLNGDLSIQTKESLTIDPNI 853
+ GT+N + + T LK S+ G + SL N
Sbjct 368 -----------QTSGTVNAAENVTLTTTDDTTLKG----RSIAGKTLTVSSGSLN---NG 409
Query 854 HTLKAIGDIELASKQGTLILAGYGGQAGNGSE-KVLNLTTTGGGISLEGASVELQGAQLN 912
TL A D + K GT + G GNG + +LT+TG S + + A L+
Sbjct 410 GTLVAGRDATV--KTGTF--SNTGTVQGNGLKVTATDLTSTGSIKSGSTLDISARNATLS 465
Query 913 AEKNIKILANNENIQIISIKNKLNNSKLSDSNKLLVDLVEIDNKLKKISINNQYTELFLA 972
+ K A +++ L N S+ +L L INN T L+
Sbjct 466 GDAGAKDSAR------VTVSGTLENRGRLVSDDVLT--------LSATQINNSGT---LS 508
Query 973 DVKILENAYDIAFNFNPSAYKEDASYRKGSDKDIQFFNEVYDGFVKKYSDIIEPNIYSQQ 1032
K L + D S D + S E G + Q
Sbjct 509 GAKELVASADTLTTTEKSVTHSDGNLMLNSASST-LAGETSAGSTVSVKGNSLKTTATAQ 567
Query 1033 LNGTKYSTQISIAVPFGDGDYARKEDILSPNGYFKYKYDQNKIRSEINYLSQLNGYEHFS 1092
G S + A DG A + DIL+ N +
Sbjct 568 TQGNSVSVDVQNAQL--DGTQAAR-DILTLN----------------------------A 596
Query 1093 SKLVSNSGSIDITSSKGISISGSELISKKGLVNIEALGALSQNYTST--IHGKDNKPKTL 1150
S+ +++SG +S+ +S+S EL S LV AL SQ T++ + GK
Sbjct 597 SEKLTHSGK---SSAPSLSLSAPELTSSGVLVG-SALNTQSQTLTNSGLLQGK------- 645
Query 1151 GASIIIDGSQ-DFYDKG---NENDQKYRFRTILKPTLINGDKGVTIRATGNSNQDNLVLQ 1206
AS+ ++ + D G + D I LI GD G+T+ SN ++
Sbjct 646 -ASLTVNTQRLDNQQNGTLYSAADLTLDIPDIRNSGLITGDNGLTLNTASLSNPGKIIAD 704
Query 1207 ATGI--TAANGDVRIE-ANKNILFDAAIEQSYDRSTTTE-------KKSSWGGLKKKYIT 1256
+ T +GD ++ A L + Q + T K G +
Sbjct 705 TLNVRATTLDGDGLLQGAGALALAGDTLSQGRNGRWLTAGDLSLRGKTLHTAGTTQGQNL 764
Query 1257 TVSENNQANAASVDISGKNIFIESKEKNPANNIDIYSGKFIANGGQV----SILSGGNIN 1312
TV +N AN+ SV +G N+ + + + + G N S+LS G ++
Sbjct 765 TVQADNWANSGSVLATG-NLTASATGQLTSTGDIMSQGDTTLNAATTDNRGSLLSAGTLS 823
Query 1313 LYTVQESSSSNEDITKKSSFSGIKYNTSKTNATRNQISEL 1352
L + +S + T + I+ N+ + T I+ L
Sbjct 824 L----DGNSLDNRGTVQGDHVTIRQNSVTNSGTFTGIAAL 859
Score = 34.7 bits (78), Expect = 0.002
Identities = 53/233 (23%), Positives = 93/233 (40%), Gaps = 28/233 (12%)
Query 1184 INGDKGVTIRATGNSNQDNLVLQATGITAANGDVRIEANKNILFDAAIEQSYDRSTTTEK 1243
+ G G+T+ + NLVL ++G NG + A +N + A Q ++++
Sbjct 319 VTGTTGLTLNQSRLVTDKNLVLSSSGQIVQNGG-ELTAGQNAMLSA---QHLNQTS---- 370
Query 1244 KSSWGGLKKKYITTVSENNQANAASVDISGKNIFIESKEKNPANNIDIYSGKFIANGGQV 1303
G + T++ + I+GK + + S N +G + G
Sbjct 371 ----GTVNAAENVTLTTTDDTTLKGRSIAGKTLTVSSGSLN--------NGGTLVAGRDA 418
Query 1304 SILSGGNINLYTVQES--SSSNEDITKKSSF-SGIKYNTSKTNATRNQISELPGILKADY 1360
++ +G N TVQ + + D+T S SG + S NAT + + +
Sbjct 419 TVKTGTFSNTGTVQGNGLKVTATDLTSTGSIKSGSTLDISARNATLSGDAGAKDSARVTV 478
Query 1361 IGIKADNDVRLVGTEFEYLQAAKIQAGRNLS----LLTASTTVTETLKKDKNS 1409
G +N RLV + L A +I LS L+ ++ T+T T K +S
Sbjct 479 SG-TLENRGRLVSDDVLTLSATQINNSGTLSGAKELVASADTLTTTEKSVTHS 530
Score = 32.3 bits (72), Expect = 0.011
Identities = 45/175 (26%), Positives = 67/175 (38%), Gaps = 19/175 (11%)
Query 77 NSANAGNR-PVIGVGQNSQGQN---VPVVNIQTPTNGVSHNIYKQMDVLPEGVVLNNSRT 132
++ NAGN V+ G+N +G N + + Q G + ++ DVL G T
Sbjct 2386 STLNAGNNLSVVATGKN-RGDNRGDIVIAGSQLKAGG-NTSLDAANDVLLSGAANTQKTT 2443
Query 133 GANSSLVGTVGANPFLAKGEARI-ILNEVNSSVASRFEGN----LEVAGQRADVIIANPA 187
G NSS G VG + A I + VN++ S +GN E + N
Sbjct 2444 GRNSSSGGGVGVSIGAGGNGAGISVFASVNAAKGSE-KGNGTEWTETTIDSGKTVTINSG 2502
Query 188 GINIKGGGFINANKAILTTGKPQLNAD-------GSIQQFVVDQGKITISANSGS 235
+ G +N N+ I G L + S Q V G T + +GS
Sbjct 2503 RDTVLNGAQVNGNRIIADVGHDLLISSQQDTSKYDSKQTSVAAGGSFTFGSMTGS 2557
Score = 27.7 bits (60), Expect = 0.27
Identities = 27/106 (25%), Positives = 44/106 (42%), Gaps = 7/106 (7%)
Query 1519 VTAGAGSAVVGALGGSATTLGGSAVVMTQAAVTSLATQASVSLINNGGDLGKTLKDLGSK 1578
+ AG + V + T+ G+ + +T +TS + S S ++ D G+K
Sbjct 412 LVAGRDATVKTGTFSNTGTVQGNGLKVTATDLTSTGSIKSGSTLDISARNATLSGDAGAK 471
Query 1579 DSVKNLAASVVTAGLLSQVGSALNLKPDTSGFSARLLNNFTTAVGS 1624
DS A V +G L G ++ D SA +NN T G+
Sbjct 472 DS-----ARVTVSGTLENRGRLVS--DDVLTLSATQINNSGTLSGA 510
Score = 26.6 bits (57), Expect = 0.61
Identities = 32/150 (21%), Positives = 62/150 (41%), Gaps = 14/150 (9%)
Query 1257 TVSENNQANAASVDISGKNIFIESKEKNPANNIDIYSGKFIANGGQVSILSGGNINLYTV 1316
T+ + + +V ++G NI N N++ + S I N I +GG +NL +
Sbjct 1833 TLHNGSVISGNNVQLAGGNITNSGGSINAQNDLLLDSTGSIDNLNAGLINAGGALNLKAI 1892
Query 1317 QESSSSNEDITKKS----SFSGIKYNTSKT-----NATRNQIS-----ELPGILKADYIG 1362
+ + + I+ K+ S +G N ++T N N S L + D +
Sbjct 1893 GDIGNISSVISGKTVSLESATGNISNLTRTEQWAMNNGYNHFSGTDTGPLAAVRATDSLF 1952
Query 1363 IKADNDVRLVGTEFEYLQAAKIQAGRNLSL 1392
+ A D+ + G + + AG +L++
Sbjct 1953 MGAAGDISITGAAVSAGDSVLLSAGNDLNM 1982
>Q0T963 tRNA nuclease CdiA [Escherichia coli O6:K15:H31 (strain
536 / UPEC)]
Length=3242
Score = 232 bits (592), Expect = 2e-63
Identities = 248/862 (29%), Positives = 384/862 (45%), Gaps = 111/862 (13%)
Query 85 PVIGVGQNSQGQNVPVVNIQTPTN-GVSHNIYKQMDVLPEGVVLNNSRTGAN-SSLVGTV 142
P G G + VPVVNI TP G+SHN + +V EG++LNN+ N + L G +
Sbjct 36 PQNGAGMDKAANGVPVVNIATPNGAGISHNRFTDYNVGKEGLILNNATGKLNPTQLGGLI 95
Query 143 GANPFL-AKGEARIILNEVNSSVASRFEGNLEVAGQRADVIIANPAGINIKGGGFINANK 201
NP L A GEA+ I+NEV S +G EVAG+ A+V++ANP GI G GFIN
Sbjct 96 QNNPNLKAGGEAKGIINEVTGGNRSLLQGYTEVAGKAANVMVANPYGITCDGCGFINTPH 155
Query 202 AILTTGKPQLNADGSIQQFVVDQGKITISANSGSSLGLGGNKNNADYVDLYARALELNAQ 261
A LTTG+P +NADGS+Q V +G ITI+ G G + +D V + ARA E+NA
Sbjct 156 ATLTTGRPVMNADGSLQALEVTEGSITIN-------GAGLDGTRSDAVSIIARATEVNAA 208
Query 262 LYANKDIQAITGANNISADLQQISTRTGTGTTPTLAIDVKNLGGMYANNIYLLGNEKGLG 321
L+A KD+ GAN I+AD ++S G G P +A+D LGGMYA I+L E G+G
Sbjct 209 LHA-KDLTVTAGANRITAD-GRVSALKGEGDVPKVAVDTGALGGMYARRIHLTSTESGVG 266
Query 322 VSNAGTIRAVNNLVVTSAGKIEHKGSLESTSNTQGLVSIQTTQTGDNGNINSSGSITSKS 381
V+ +++++SAGK+ K SL + TT TG +++ SG +
Sbjct 267 VNLGNLYARDGDIILSSAGKLVLKNSLAGGN---------TTVTGT--DVSLSGDNKAGG 315
Query 382 MLSIDAANHLNITGNQVIVNQGVVSPLLLSAQGDINVSNGAIIKNVQTGGDIYLDAQNIN 441
LS+ L + +++ ++ L+LS+ G I V NG + G + L AQ++N
Sbjct 316 NLSVTGTTGLTLNQPRLVTDKN----LVLSSSGQI-VQNGG---ELTAGQNAMLSAQHLN 367
Query 442 VGENTQIANVGLVNLNAAAAIDIKKSARVKAVNDLNIIAKQGLSVADANLVAEKGNMN-- 499
T +NAA ++ + ND + +G S+A L G++N
Sbjct 368 QTSGT---------VNAA------ENVTLTTTNDTTL---KGRSIAGKTLTVSSGSLNNG 409
Query 500 --LQSNSNITLQGTTLDLTKDLNINGTGNVNLSSLNFSLLNGSSTLQNINAYSGLNLVWD 557
L + + T++ T T + NG + + STL +I+A + L D
Sbjct 410 GTLVAGRDATVKTGTFSNTGTVQGNGLKVTATDLTSTGSIKSGSTL-DISARNA-TLSGD 467
Query 558 QTAKALPQISGNVTLEAANLIDLKGSNLSGKGDLKLQGKALNVGADLTAGKSLNLTATQS 617
AK +++ + TLE L L L +N L+ K L +A
Sbjct 468 AGAKDSARVTVSGTLE-------NRGRLVSDDVLTLSATQINNSGTLSGAKELVASADTL 520
Query 618 DLILNKTLNAQGNIDIASLDGKLNATGLNATSSQGKLSIFGAKDTVLTNSGTVKTTLKGN 677
N+ GN+ + S ++T TS+ G +S+ G ++KTT
Sbjct 521 TTTEKSVTNSDGNLMLDS----ASSTLAGETSAGGTVSVKG---------NSLKTTTTAQ 567
Query 678 QGVNVGTISTGNLTLQNTVLESQNGAIVVTSEGQNTLTDSIITAKGNIELFAKDNLTLDG 737
N ++ N L T Q ++T LT S ++ ++ L A + LT G
Sbjct 568 TQGNSVSVDVQNAQLDGT----QAARDILTLNASEKLTHSGKSSAPSLSLSAPE-LTSSG 622
Query 738 IKSSSQQHTALNSKKNIYINSQAGTGDSVNFSSTKITELNSTGTLSLISDKNQNLQNTRL 797
+ S ALN++ NS G++ +T+ + GTL +D ++ + R
Sbjct 623 VLVGS----ALNTQSQTLTNSGLLQGEASLTVNTQRLDNQQNGTLYSAADLTLDIPDIRN 678
Query 798 TG-----GAILLEAGGTLNTPKVI----EFNAT---GSNLLKNDSKLNSLNGDLSIQTKE 845
+G ++L A N K+I AT G LL+ L +L GD Q
Sbjct 679 SGLITGDNGLMLNAVSLSNPGKIIADTLSVRATTLDGDGLLQGAGAL-ALAGDTLSQGSH 737
Query 846 SLTIDPNIHTLKAIGDIELASKQGTLILAGYGGQAGNGS---------EKVLNLTTTG-- 894
+ + +L+ + QG I A +GS LT+TG
Sbjct 738 GRWLTADDLSLRGKTLNTAGTTQGQNITVQADRWANSGSVLATGNLTASATGQLTSTGDI 797
Query 895 ---GGISLEGASVELQGAQLNA 913
G +L+ A+ + +G+ L+A
Sbjct 798 MSQGDTTLKAATTDNRGSLLSA 819
Score = 84.0 bits (206), Expect = 3e-18
Identities = 198/866 (23%), Positives = 338/866 (39%), Gaps = 155/866 (18%)
Query 125 VVLNNSRTGANSSLVGTVGANPFLAKGEARIILNEVNSSVASRFEGNLEVAGQRADVI-- 182
+VL NS G N+++ GT +V+ S ++ GNL V G +
Sbjct 287 LVLKNSLAGGNTTVTGT-----------------DVSLSGDNKAGGNLSVTGTTGLTLNQ 329
Query 183 --IANPAGINIKGGGFINANKAILTTGKPQLNADGSIQQFVVDQGKITISAN----SGSS 236
+ + + G I N LT G+ NA S Q G + + N + +
Sbjct 330 PRLVTDKNLVLSSSGQIVQNGGELTAGQ---NAMLSAQHLNQTSGTVNAAENVTLTTTND 386
Query 237 LGLGGNKNNADYVDLYARALELNAQLYANKDIQAITGANNISADLQQISTR-TGTGTTPT 295
L G + + + +L L A +D TG + + +Q + T T T T
Sbjct 387 TTLKGRSIAGKTLTVSSGSLNNGGTLVAGRDATVKTGTFSNTGTVQGNGLKVTATDLTST 446
Query 296 LAIDVKNLGGMYANNIYLLGNEKGLGVSNAGTIRAVNNLVVTSAGKIEHKGSLESTSNTQ 355
+I + + A N L G+ AG A ++ VT +G +E++G L S
Sbjct 447 GSIKSGSTLDISARNATLSGD--------AG---AKDSARVTVSGTLENRGRLVSDD--- 492
Query 356 GLVSIQTTQTGDNGNINSSGS-ITSKSMLSIDAANHLNITGNQVIVNQGVVSPLLLSAQG 414
++++ TQ ++G ++ + + S L+ + N GN ++ + SA G
Sbjct 493 -VLTLSATQINNSGTLSGAKELVASADTLTTTEKSVTNSDGNLMLDSASSTLAGETSAGG 551
Query 415 DINVSNGAI--IKNVQT-GGDIYLDAQNINVGENTQIANVGLVNLNAAAAIDIK-KSARV 470
++V ++ QT G + +D QN + + TQ A ++ LNA+ + KS+
Sbjct 552 TVSVKGNSLKTTTTAQTQGNSVSVDVQNAQL-DGTQAAR-DILTLNASEKLTHSGKSSAP 609
Query 471 KAVNDLNIIAKQGLSVADANLVAEKGNMN---LQSNSNITLQGTTLDLTKDLNINGTGNV 527
+ G+ V A + N LQ +++T+ LD ++ + ++
Sbjct 610 SLSLSAPELTSSGVLVGSALNTQSQTLTNSGLLQGEASLTVNTQRLDNQQNGTLYSAADL 669
Query 528 NLSS---LNFSLLNGSSTLQNINAYSGLN---LVWDQTAKALPQISGNVTLEAANLIDLK 581
L N L+ G + L +NA S N ++ D + + G+ L+ A + L
Sbjct 670 TLDIPDIRNSGLITGDNGLM-LNAVSLSNPGKIIADTLSVRATTLDGDGLLQGAGALALA 728
Query 582 GSNLSGKG--------DLKLQGKALNVGADLTAGKSLNLTATQSDLILNK-TLNAQGNID 632
G LS DL L+GK LN A T G+++ + Q+D N ++ A GN+
Sbjct 729 GDTLSQGSHGRWLTADDLSLRGKTLNT-AGTTQGQNITV---QADRWANSGSVLATGNLT 784
Query 633 IASLDGKLNATG---------LNATSSQGKLSIFGA-----KDTVLTNSGTVK---TTLK 675
AS G+L +TG L A ++ + S+ A L NSGTV+ T++
Sbjct 785 -ASATGQLTSTGDIMSQGDTTLKAATTDNRGSLLSAGTLSLDGNSLDNSGTVQGDHVTIR 843
Query 676 GNQGVNVGTIS-TGNLTLQNTVLESQ-----NGAIVVTSEGQNTLTDSIITAKGNIELFA 729
N N GT++ LTL ++ Q NG ++TS G T+T + G I+ A
Sbjct 844 QNSVTNSGTLTGIAALTLAARMVSPQPALMNNGGSLLTS-GDLTITAGSLVNSGAIQ--A 900
Query 730 KDNLTLDGIKSSSQQHTALNSKKNIYINSQAGTGDSVNFSSTKITELNSTGTLSLISDKN 789
D+LT TG+ V+ + +K+T N LS ++ N
Sbjct 901 ADSLTA------------------------RLTGELVSTAGSKVTS-NGEMALSALNLSN 935
Query 790 QNLQNTR-LTGGAILLEAGGTLNTPKVIEFNATGSNLLKNDSKLNSLNGDLSIQTKESLT 848
+ LT A L + G + + L N + N NG L
Sbjct 936 SGQWIAKNLTLKANSLTSAGDITGVDTL-------TLTVNQTLNNQANGKL--------- 979
Query 849 IDPNIHTLKAIGDIELASKQGTLILAGYGGQAGNGSEKVLNLTTTGGGISLEGASVELQG 908
+ + TLKA + + G L GN + T GG + E ++ G
Sbjct 980 LSAGVLTLKA----DSVTNDGQL--------QGNATTITAGQLTNGGHLQGETLTLAASG 1027
Query 909 AQLNAEKNIKILANNENIQIISIKNK 934
N + + N N+ ++ N+
Sbjct 1028 GVNNRFGGVLMSRNALNVSTATLSNQ 1053
Score = 73.2 bits (178), Expect = 5e-15
Identities = 221/1093 (20%), Positives = 427/1093 (39%), Gaps = 188/1093 (17%)
Query 135 NSSLVGTVGANPFLAKGEARIILNEVNSSVASRFEGNLEVAGQRADVIIANPAGINIKGG 194
N++L G GA K AR+ ++ G LE G+ + + I
Sbjct 461 NATLSGDAGA-----KDSARVTVS-----------GTLENRGRLVSDDVLTLSATQINNS 504
Query 195 GFINANKAIL-------TTGKPQLNADGSIQQFVVDQGKITISA--NSGSSLGLGGNK-N 244
G ++ K ++ TT K N+DG++ ++D T++ ++G ++ + GN
Sbjct 505 GTLSGAKELVASADTLTTTEKSVTNSDGNL---MLDSASSTLAGETSAGGTVSVKGNSLK 561
Query 245 NADYVDLYARALELNAQLYANKDIQAITGANNI-SADLQQISTRTGTGTTPTLAIDVKNL 303
++ ++ Q N + A +I + + + T +G + P+L++ L
Sbjct 562 TTTTAQTQGNSVSVDVQ---NAQLDGTQAARDILTLNASEKLTHSGKSSAPSLSLSAPEL 618
Query 304 GGMYANNIYLLG---NEKGLGVSNAGTIRAVNNLVV-TSAGKIEHKGSLESTSN-TQGLV 358
++ L+G N + ++N+G ++ +L V T + G+L S ++ T +
Sbjct 619 ----TSSGVLVGSALNTQSQTLTNSGLLQGEASLTVNTQRLDNQQNGTLYSAADLTLDIP 674
Query 359 SIQTTQ--TGDNGNINSSGSITSKSMLSID--AANHLNITGNQVIVNQGVVSPLLLSAQG 414
I+ + TGDNG + ++ S+++ + D + + G+ ++ G L+ G
Sbjct 675 DIRNSGLITGDNGLMLNAVSLSNPGKIIADTLSVRATTLDGDGLLQGAGA-----LALAG 729
Query 415 DINVSNGAIIKNVQTGGDIYLDAQNINVGENTQIANVGLVNLNAAAAIDIKKSARVKAVN 474
D +S G+ + + T D+ L + +N TQ N+ + + N
Sbjct 730 D-TLSQGSHGRWL-TADDLSLRGKTLNTAGTTQGQNITV--------------QADRWAN 773
Query 475 DLNIIAKQGLSVADANLVAEKGNMNLQSNSNITLQGTTLDLTKDLNINGTGNVNLSSLNF 534
+++A L+ + + G+ + S + TL+ T D L GT SL+
Sbjct 774 SGSVLATGNLTASATGQLTSTGD--IMSQGDTTLKAATTDNRGSLLSAGT-----LSLDG 826
Query 535 SLLNGSSTLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANLIDLKGSNLSGKGDLKLQ 594
+ L+ S T+Q D ++ + TL + L +S + L
Sbjct 827 NSLDNSGTVQG-----------DHVTIRQNSVTNSGTLTGIAALTLAARMVSPQPALMNN 875
Query 595 GKALNVGADLTAGKSLNLTATQSDLILNKTLNAQGNIDIASLDGKLNATGLNATSSQGKL 654
G +L LT+G +LT T L+ + + A ++ A L G+L +T + +S G++
Sbjct 876 GGSL-----LTSG---DLTITAGSLVNSGAIQAADSLT-ARLTGELVSTAGSKVTSNGEM 926
Query 655 SIFGAKDTVLTNSG---TVKTTLKGNQGVNVGTIS---TGNLTLQNTVLESQNGAIV--- 705
++ L+NSG TLK N + G I+ T LT+ T+ NG ++
Sbjct 927 ALSALN---LSNSGQWIAKNLTLKANSLTSAGDITGVDTLTLTVNQTLNNQANGKLLSAG 983
Query 706 --------VTSEGQ-----NTLTDSIITAKGNIELFAKDNLTL---DGIKSSS----QQH 745
VT++GQ T+T +T G+++ + LTL G+ +
Sbjct 984 VLTLKADSVTNDGQLQGNATTITAGQLTNGGHLQ---GETLTLAASGGVNNRFGGVLMSR 1040
Query 746 TALNSKKNIYINS---QAGTGDSVNFSST--KITELNSTGTLSLISDKNQNLQNTRLTGG 800
ALN N Q G G S+N + +++ S L+L + N + +
Sbjct 1041 NALNVSTATLSNQGTIQGGGGVSLNVTDRLQNDSKILSGSNLTLTAQVLANTGSGLVQAA 1100
Query 801 AILLEAGGTLNTPKVIEFNATGSNLLKNDSKLNSLNGDLSIQTKESLTIDPNIHTLK--- 857
+LL+ T+N +V+ ATGS D K +LN ++Q + L N HT
Sbjct 1101 TLLLDVVNTVNGGRVL---ATGSA----DVKGTTLNNTGTLQGADLLV---NYHTFSNSG 1150
Query 858 -AIGDIELASKQGTLILAGYGGQAGNGSEKVLNLTTTGGGISLEGASVELQGAQLNAEKN 916
+G L K +L+ G G G+ + +G G + V L+ + A N
Sbjct 1151 TLLGTSGLGVKGSSLLQHGTGRLYSAGNLLLDAQDFSGQGQVVATGDVTLK--LIAALTN 1208
Query 917 IKILANNENIQIISIKNKLNNSKLSDSNKLLVDLVEIDNKLKKISINNQYTELFLADVKI 976
LA + + + S +N + N + + +++ E F + +
Sbjct 1209 HGTLAAGKTLSVTS-QNAITNGGVMQGDAMVLGA----------------GEAFTNNGML 1251
Query 977 LENAYDIAFNFNPSAYKEDASYRKGSDKDIQFFNEVYDGFVKKYSDIIEPNIYSQQLNGT 1036
+ F+ S + G D + +++ + + N+ LN
Sbjct 1252 TAGKGNSVFSAQRLFLNAPGSLQAGGDVSLNSRSDITISGFTGTAGSLTMNVAGTLLNSA 1311
Query 1037 KYSTQISIAVPFGDGDYARKEDILSPNGYFKYKYDQNKIRSEINYLSQLNGYEHFSSKLV 1096
++ + F D + + DIL+ N + K +EI +
Sbjct 1312 LIYAGNNLKL-FTDRLHNQHGDILAGNSLWVQKDASGGANTEI----------------I 1354
Query 1097 SNSGSIDITSSKGISISGSELISKKGLVNIEALGALSQNYTSTIHGKDNKPKTLGASIII 1156
+ SG+I+ + +G L ++G + ++ S+I G N + S++
Sbjct 1355 NTSGNIETHQGDIVVRTGHLLNQREGF----SATTTTRTNPSSIQGMGNALVDIPLSLLP 1410
Query 1157 DGSQDFYDKGNEN 1169
DGS ++ + EN
Sbjct 1411 DGSYGYFTREVEN 1423
Score = 71.6 bits (174), Expect = 1e-14
Identities = 160/792 (20%), Positives = 319/792 (40%), Gaps = 113/792 (14%)
Query 225 GKITISANSGSSLGL--GGNKNNADYVDLYARALELNAQLYA---NKDIQAITGANNISA 279
G IT NSGSS+ G + ++ Y+D LNA L + + D+ AI +NIS+
Sbjct 1866 GNIT---NSGSSINAQNGLSLDSTGYID------NLNAGLISAGGSLDLSAIGDISNISS 1916
Query 280 DLQ----QISTRTGTGTTPTLAIDVKNLGGMYANNIYLLGNEKGLGVSNAGTIRAVNNLV 335
+ Q+ + +G + T ++L G + G TI+ ++L
Sbjct 1917 VISGKTVQLESVSGNISNITRRQQWNAGSDSRYGGVHLSGTDTG----PVATIKGTDSLS 1972
Query 336 VTSAGKIEHKGSLESTSNTQG------------LVSIQTTQTG----DNGNINSS----G 375
+ + I+ G+ S+ T G L+S +Q+G D+ + +S+
Sbjct 1973 LDAGKNIDITGATVSSGGTLGMSAGNDINIAANLISGSKSQSGFWHTDDNSASSTTSQGS 2032
Query 376 SITSKSMLSIDAANHLNITGNQVIVNQGVVSPLLLSAQGDINVSNGAIIKNVQTGG---- 431
SI++ L++ A ++L++T + V LLSA D++++ KN + G
Sbjct 2033 SISAGGNLAMAAGHNLDVTASSVSAGHSA----LLSAGNDLSLNAVRESKNSRNGRSESH 2088
Query 432 DIYLDAQNINVGENTQIANVGLVNLNAAAAIDIKKSARVKAVNDLNIIAKQGLSVADANL 491
+ + + G+N + G + AA + + + ++ D+N++A+ D+
Sbjct 2089 ESHAAVSTVTAGDNLLLV-AGRDVASQAAGVAAENNVVIRGGRDVNLVAESA-GAGDSYT 2146
Query 492 VAEKGNMNLQSNSNITLQGTTLDLTKDLNINGTGNVNLSSLNFSLLNGSSTLQNINAYSG 551
+K +N + QGT + D +N ++ ++ + + NI+ +G
Sbjct 2147 SKKKKEIN----ETVRQQGTEIASGGDTTVNAGRDIT------AVASSVTATGNISVNAG 2196
Query 552 LNLVWDQTAKALPQISGNVTLEAANLIDLKGSNLSGKGDLKLQGKALNVGADLTAGKSLN 611
++ TA ++ + K ++ + + +L G +T N
Sbjct 2197 RDVALT-TATESDYHYLETKKKSGGFLSKKTTHTISEDSASREAGSLLSGNRVTVNAGDN 2255
Query 612 LTATQSDLILNK--TLNAQGNIDIASLDGKLNATGLNATSSQGKLSIFGAKDTVLTNSGT 669
LT SD++ ++ +L A ++D+ + + T G + G T+ ++ T
Sbjct 2256 LTVEGSDVVADQDVSLAAGNHVDVLAATSTDTSWRFKETKKSGLMGTGGIGFTIGSSKTT 2315
Query 670 VKTTLKGN-QGVNVGTIST--GNLTLQNTVLESQNGAIVVTSEGQNTLTDSIITAKGNI- 725
G Q + TI + GN+++ +G+ V+ + + DS++ G+
Sbjct 2316 HDRREAGTTQSQSASTIGSTAGNVSITAGKQAHISGSDVIANRDISITGDSVVVDPGHDR 2375
Query 726 ----ELFA--KDNLTL------------------DGIKSSSQQHTALNSKKNIYINSQAG 761
E F K LT+ + +SS + AL + K QAG
Sbjct 2376 RTVDEKFEQKKSGLTVALSGTVGSAINNAVTSAQETKESSDSRLKALQATKTALSGVQAG 2435
Query 762 TGDSVNFSSTKITELNSTG-TLSLISDKNQNLQNTRLTGGAILLEAGGTLNTPKVIEFNA 820
++ ++ + N+TG +LSL + K+++ Q++ +G TLN + A
Sbjct 2436 QAATM---ASATGDPNATGVSLSLTTQKSKSQQHSESD-----TVSGSTLNAGNNLSVVA 2487
Query 821 TGSNLLKNDSKLNSLNGDLSIQTKESLTIDPNIHTLKAIGDIELASKQGTLILAGYGGQA 880
TG N + D++ GD+ I + L + N +L A DI L+ T G +
Sbjct 2488 TGKN--RGDNR-----GDIVIAGSQ-LKVGGNT-SLDAANDILLSGAANTQKTTGRNSSS 2538
Query 881 GNGSEKVLNLTTTGGGISLEGASVELQGAQL--NAEKNIKILANNENIQIISIKNKLNNS 938
G G + G GIS+ +G++ E + + + I S ++ + N
Sbjct 2539 GGGVGVSIGAGGNGAGISVFAGVNAAKGSEKGNGTEWTETTTDSGKTVTINSGRDTVLNG 2598
Query 939 KLSDSNKLLVDL 950
+ N+++ D+
Sbjct 2599 AQVNGNRIIADV 2610
Score = 67.8 bits (164), Expect = 2e-13
Identities = 150/687 (22%), Positives = 270/687 (39%), Gaps = 151/687 (22%)
Query 344 HKGSLESTSNTQGLVSIQTTQTGDNGNINSSGS-ITSKSMLSIDAANHLNITGNQVIVNQ 402
H GS+ S +N Q GNI +SGS I +++ LS+D+ +++ +N
Sbjct 1851 HNGSVISGNNVQLA----------GGNITNSGSSINAQNGLSLDSTGYIDN------LNA 1894
Query 403 GVVSP---LLLSAQGDIN----VSNGAIIKNVQTGGDI--YLDAQNINVGENTQIANVGL 453
G++S L LSA GDI+ V +G ++ G+I Q N G +++ V L
Sbjct 1895 GLISAGGSLDLSAIGDISNISSVISGKTVQLESVSGNISNITRRQQWNAGSDSRYGGVHL 1954
Query 454 ----------------VNLNAAAAIDIKKSARVKAVNDLNIIAKQGLSVADANLVA---- 493
++L+A IDI A V + L + A +++A ANL++
Sbjct 1955 SGTDTGPVATIKGTDSLSLDAGKNIDIT-GATVSSGGTLGMSAGNDINIA-ANLISGSKS 2012
Query 494 EKGNMNLQSNS--NITLQGTTLDLTKDLNINGTGNVNLSSLNFSLLNGSSTLQNINAYSG 551
+ G + NS + T QG+++ +L + N+++++ + S G S L +
Sbjct 2013 QSGFWHTDDNSASSTTSQGSSISAGGNLAMAAGHNLDVTASSVSA--GHSALLSAGNDLS 2070
Query 552 LNLVWDQTAKALPQISGNVTLEAANLIDLKGSNLSGKGDLKLQGKALNVGAD----LTAG 607
LN V + + + + A + + G NL + +A V A+ + G
Sbjct 2071 LNAVRESKNSRNGRSESHESHAAVSTVTA-GDNLLLVAGRDVASQAAGVAAENNVVIRGG 2129
Query 608 KSLNLTA----------TQSDLILNKTLNAQGNIDIASLDGKLNA-----TGLNATSSQG 652
+ +NL A ++ +N+T+ QG + D +NA ++ ++ G
Sbjct 2130 RDVNLVAESAGAGDSYTSKKKKEINETVRQQGTEIASGGDTTVNAGRDITAVASSVTATG 2189
Query 653 KLSIFGAKDTVLTNSGTVKTTLKGNQGVNVGTISTGNLTLQNTVLESQNGAIVVTSEGQN 712
+S+ +D LT + T + S G L+ + T S++ A + E +
Sbjct 2190 NISVNAGRDVALTTA-----TESDYHYLETKKKSGGFLSKKTTHTISEDSA---SREAGS 2241
Query 713 TLTDSIITAKGNIELFAKDNLTLDGIKSSSQQHTALNSKKNIYINSQAGTGDSVNFSSTK 772
L+ + +T A DNLT++G + Q +L + ++ + + T S F TK
Sbjct 2242 LLSGNRVTVN------AGDNLTVEGSDVVADQDVSLAAGNHVDVLAATSTDTSWRFKETK 2295
Query 773 ITELNSTGTLSLISDKNQNLQNTRLTGGAILLEAGGTLNTPKVIEFNATGSNLLKNDSKL 832
+ L TG + ++ + R GT + +T N+ K
Sbjct 2296 KSGLMGTGGIGFTIGSSKTTHDRR---------EAGTTQSQSASTIGSTAGNVSITAGKQ 2346
Query 833 NSLNG-------DLSIQTKESLTIDPNIHTLKAIGDIELASKQG-TLILAGYGGQAGNGS 884
++G D+SI T +S+ +DP H + + + K G T+ L+G G A N +
Sbjct 2347 AHISGSDVIANRDISI-TGDSVVVDPG-HDRRTVDEKFEQKKSGLTVALSGTVGSAINNA 2404
Query 885 E--------------KVLNLTTTG----------------GGISLEGASVEL-------- 906
K L T T G + G S+ L
Sbjct 2405 VTSAQETKESSDSRLKALQATKTALSGVQAGQAATMASATGDPNATGVSLSLTTQKSKSQ 2464
Query 907 --------QGAQLNAEKNIKILANNEN 925
G+ LNA N+ ++A +N
Sbjct 2465 QHSESDTVSGSTLNAGNNLSVVATGKN 2491
Score = 63.2 bits (152), Expect = 5e-12
Identities = 48/133 (36%), Positives = 66/133 (50%), Gaps = 11/133 (8%)
Query 1644 LLAGLAGAMQGELASQIGTHLDKVDPNVFEYAIHKIAHAAVGCAVAAATKSSCEAGAIGA 1703
+ LAGA ELA+ IG H +D N A IAHA +G AA +S AGAIGA
Sbjct 2897 MAGALAGASAPELANIIGHHAG-IDDNT---AAKAIAHAILGGVTAALQGNSAAAGAIGA 2952
Query 1704 GVGEIVASLMPDP----VNGIEYNEDEKTKIRNTGKIVAGVVSAYAGYDVNTAANSADI- 1758
G GE++AS + V+ + ED+K + + AG+ A DV AA A
Sbjct 2953 GTGEVIASAIAKSLYPGVDPSKLTEDQKQTVSTLATLSAGMAGGIASGDVAGAAAGAGAG 3012
Query 1759 --AIQNNSLVKLA 1769
++NN+L +A
Sbjct 3013 KNVVENNALSLVA 3025
Score = 51.2 bits (121), Expect = 2e-08
Identities = 57/234 (24%), Positives = 103/234 (44%), Gaps = 20/234 (9%)
Query 1195 TGNSNQDNLVLQATGITAANGDVRIEANKNILFDAAIEQSYDRSTTTEKKSSWGGLKKKY 1254
T N+ +D + A+ +TA G++ + A +++ A E Y T KK S G L KK
Sbjct 2171 TVNAGRD-ITAVASSVTAT-GNISVNAGRDVALTTATESDYHYLET--KKKSGGFLSKKT 2226
Query 1255 ITTVSENNQANAASVDISGKNIFIESKEKNPANNIDIYSGKFIANGGQVSILSGGNINLY 1314
T+SE++ + A +SG + + N +N+ + +A+ VS+ +G ++++
Sbjct 2227 THTISEDSASREAGSLLSGNRVTV-----NAGDNLTVEGSDVVAD-QDVSLAAGNHVDVL 2280
Query 1315 TVQESSSS-NEDITKKSSFS-----GIKYNTSKTNATRNQISELPGILKADYIGIKADND 1368
+ +S TKKS G +SKT R + A IG A N
Sbjct 2281 AATSTDTSWRFKETKKSGLMGTGGIGFTIGSSKTTHDRREAGTTQS-QSASTIGSTAGN- 2338
Query 1369 VRLVGTEFEYLQAAKIQAGRNLSLLTASTTVTETLKKDKNSVVWQSMQDKGSVT 1422
V + + ++ + + A R++S+ S V D+ +V + Q K +T
Sbjct 2339 VSITAGKQAHISGSDVIANRDISITGDSVVVDP--GHDRRTVDEKFEQKKSGLT 2390
Score = 42.7 bits (99), Expect = 8e-06
Identities = 83/355 (23%), Positives = 144/355 (41%), Gaps = 84/355 (24%)
Query 1096 VSNSGSIDITSSKGISISGSE--------LISKKGLVNIEALGALSQNYTSTIHGKDNKP 1147
++NSGS I + G+S+ + LIS G +++ A+G +S N +S I GK +
Sbjct 1868 ITNSGS-SINAQNGLSLDSTGYIDNLNAGLISAGGSLDLSAIGDIS-NISSVISGKTVQL 1925
Query 1148 KTLGASIIIDGSQDFYDKGNENDQKY-----------RFRTILKPTLINGDKGVTIRATG 1196
+++ +I + ++ G +D +Y TI ++ D G I TG
Sbjct 1926 ESVSGNISNITRRQQWNAG--SDSRYGGVHLSGTDTGPVATIKGTDSLSLDAGKNIDITG 1983
Query 1197 NSNQDNLVLQATGITAANGDVRIEANKNILFDAAIEQSYDRSTTTEKKSSWGGLKKKYIT 1256
+ L G++A N D+ I AN L + QS T SS
Sbjct 1984 ATVSSGGTL---GMSAGN-DINIAAN---LISGSKSQSGFWHTDDNSASS---------- 2026
Query 1257 TVSENNQANAASVDISGKNIFIESKEKNPANNIDIYSGKFIANGGQVSILSGGN-INLYT 1315
T S+ + +A G N+ + + +N+D+ + + G ++LS GN ++L
Sbjct 2027 TTSQGSSISA------GGNLAMAA-----GHNLDVTASS--VSAGHSALLSAGNDLSLNA 2073
Query 1316 VQESSSS-NEDITKKSSFSGIKYNTSKTN----ATRNQISELPGILKADYIGIKADNDVR 1370
V+ES +S N S + + T+ N A R+ S+ G+ + + I+ DV
Sbjct 2074 VRESKNSRNGRSESHESHAAVSTVTAGDNLLLVAGRDVASQAAGVAAENNVVIRGGRDVN 2133
Query 1371 LV-------------------------GTEFEYLQAAKIQAGRNLSLLTASTTVT 1400
LV GTE + AGR+++ + +S T T
Sbjct 2134 LVAESAGAGDSYTSKKKKEINETVRQQGTEIASGGDTTVNAGRDITAVASSVTAT 2188
Score = 37.7 bits (86), Expect = 3e-04
Identities = 55/233 (24%), Positives = 92/233 (39%), Gaps = 28/233 (12%)
Query 1184 INGDKGVTIRATGNSNQDNLVLQATGITAANGDVRIEANKNILFDAAIEQSYDRSTTTEK 1243
+ G G+T+ NLVL ++G NG + A +N + A Q ++++
Sbjct 319 VTGTTGLTLNQPRLVTDKNLVLSSSGQIVQNGG-ELTAGQNAMLSA---QHLNQTS---- 370
Query 1244 KSSWGGLKKKYITTVSENNQANAASVDISGKNIFIESKEKNPANNIDIYSGKFIANGGQV 1303
G + T++ N I+GK + + S N +G + G
Sbjct 371 ----GTVNAAENVTLTTTNDTTLKGRSIAGKTLTVSSGSLN--------NGGTLVAGRDA 418
Query 1304 SILSGGNINLYTVQES--SSSNEDITKKSSF-SGIKYNTSKTNATRNQISELPGILKADY 1360
++ +G N TVQ + + D+T S SG + S NAT + + +
Sbjct 419 TVKTGTFSNTGTVQGNGLKVTATDLTSTGSIKSGSTLDISARNATLSGDAGAKDSARVTV 478
Query 1361 IGIKADNDVRLVGTEFEYLQAAKIQAGRNLS----LLTASTTVTETLKKDKNS 1409
G +N RLV + L A +I LS L+ ++ T+T T K NS
Sbjct 479 SG-TLENRGRLVSDDVLTLSATQINNSGTLSGAKELVASADTLTTTEKSVTNS 530
Score = 37.7 bits (86), Expect = 3e-04
Identities = 52/269 (19%), Positives = 103/269 (38%), Gaps = 48/269 (18%)
Query 1188 KGVTIRATGN---SNQDNLVLQATGITAANGDVRIEANKNILFDAAIEQSYDRSTTTEKK 1244
+G +I A GN + NL + A+ ++A + + + A ++ +A E R+ +E
Sbjct 2030 QGSSISAGGNLAMAAGHNLDVTASSVSAGHSAL-LSAGNDLSLNAVRESKNSRNGRSESH 2088
Query 1245 SSWGGLK-----------------KKYITTVSENNQANAASVDIS------GKNIFIESK 1281
S + + +ENN D++ G SK
Sbjct 2089 ESHAAVSTVTAGDNLLLVAGRDVASQAAGVAAENNVVIRGGRDVNLVAESAGAGDSYTSK 2148
Query 1282 EKNPANNIDIYSGKFIANGGQVSILSGGNINLYTVQESSSSNEDI--------------- 1326
+K N G IA+GG ++ +G +I +++ N +
Sbjct 2149 KKKEINETVRQQGTEIASGGDTTVNAGRDITAVASSVTATGNISVNAGRDVALTTATESD 2208
Query 1327 -----TKKSSFSGIKYNTSKTNATRNQISELPGILKADYIGIKADNDVRLVGTEFEYLQA 1381
TKK S + T+ T + + E +L + + + A +++ + G++ Q
Sbjct 2209 YHYLETKKKSGGFLSKKTTHTISEDSASREAGSLLSGNRVTVNAGDNLTVEGSDVVADQD 2268
Query 1382 AKIQAGRNLSLLTASTTVTE-TLKKDKNS 1409
+ AG ++ +L A++T T K+ K S
Sbjct 2269 VSLAAGNHVDVLAATSTDTSWRFKETKKS 2297
Score = 32.0 bits (71), Expect = 0.014
Identities = 61/314 (19%), Positives = 113/314 (36%), Gaps = 46/314 (15%)
Query 322 VSNAGTIRAVNNLVVTSAGKIEHKGSLESTSNTQGLVSIQTTQ---TGDNGN-------- 370
++N GT+ A L VTS I + G ++ + G T T GN
Sbjct 1206 LTNHGTLAAGKTLSVTSQNAITNGGVMQGDAMVLGAGEAFTNNGMLTAGKGNSVFSAQRL 1265
Query 371 -INSSGSITSKSMLSIDAANHLNI---TGNQVIVNQGVVSPLLLSA-------------- 412
+N+ GS+ + +S+++ + + I TG + V LL SA
Sbjct 1266 FLNAPGSLQAGGDVSLNSRSDITISGFTGTAGSLTMNVAGTLLNSALIYAGNNLKLFTDR 1325
Query 413 ----QGDINVSNGAIIKNVQTGGDIYLDAQNINVGENTQIANVGLVNLNAAAAIDIKKSA 468
GDI N ++ +GG + + IN N + + G + + ++ ++
Sbjct 1326 LHNQHGDILAGNSLWVQKDASGG---ANTEIINTSGNIE-THQGDIVVRTGHLLNQREGF 1381
Query 469 RVKAVNDLNIIAKQGLSVADANL---VAEKGNMNLQSNSNITLQGTTLDLTKDLNINGTG 525
N + QG+ A ++ + G+ + GT N +G
Sbjct 1382 SATTTTRTNPSSIQGMGNALVDIPLSLLPDGSYGYFTREVENQHGT------PCNGHGAC 1435
Query 526 NVNLSSLNFSLLNGSSTLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANLIDLKGSNL 585
N+ + +L + S Q + + V A SG A ++ + S +
Sbjct 1436 NITMDTLYYYAPFADSATQRFLSSQNITTVTGADNPAGRIASGRNLSAEAERLENRASFI 1495
Query 586 SGKGDLKLQGKALN 599
GD+ L G+ L+
Sbjct 1496 LANGDIALSGRELS 1509
Score = 32.0 bits (71), Expect = 0.014
Identities = 44/175 (25%), Positives = 67/175 (38%), Gaps = 19/175 (11%)
Query 77 NSANAGNR-PVIGVGQNSQGQN---VPVVNIQTPTNGVSHNIYKQMDVLPEGVVLNNSRT 132
++ NAGN V+ G+N +G N + + Q G + ++ D+L G T
Sbjct 2475 STLNAGNNLSVVATGKN-RGDNRGDIVIAGSQLKVGG-NTSLDAANDILLSGAANTQKTT 2532
Query 133 GANSSLVGTVGANPFLAKGEARI-ILNEVNSSVASRFEGN----LEVAGQRADVIIANPA 187
G NSS G VG + A I + VN++ S +GN E + N
Sbjct 2533 GRNSSSGGGVGVSIGAGGNGAGISVFAGVNAAKGSE-KGNGTEWTETTTDSGKTVTINSG 2591
Query 188 GINIKGGGFINANKAILTTGKPQLNAD-------GSIQQFVVDQGKITISANSGS 235
+ G +N N+ I G L + S Q V G T + +GS
Sbjct 2592 RDTVLNGAQVNGNRIIADVGHDLLISSQQDTSKYDSKQTSVAAGGSFTFGSMTGS 2646
Score = 28.9 bits (63), Expect = 0.12
Identities = 35/146 (24%), Positives = 54/146 (37%), Gaps = 16/146 (11%)
Query 1479 LVNRNDVDWQKVILAQKDWDYKSQGLTGAGAAIIAIIVVMVTAGAGSAVVGALGGSATTL 1538
L ND + +A K S L G + AG + V + T+
Sbjct 381 LTTTNDTTLKGRSIAGKTLTVSSGSLNNGGTLV---------AGRDATVKTGTFSNTGTV 431
Query 1539 GGSAVVMTQAAVTSLATQASVSLINNGGDLGKTLKDLGSKDSVKNLAASVVTAGLLSQVG 1598
G+ + +T +TS + S S ++ D G+KDS A V +G L G
Sbjct 432 QGNGLKVTATDLTSTGSIKSGSTLDISARNATLSGDAGAKDS-----ARVTVSGTLENRG 486
Query 1599 SALNLKPDTSGFSARLLNNFTTAVGS 1624
++ D SA +NN T G+
Sbjct 487 RLVS--DDVLTLSATQINNSGTLSGA 510
Score = 28.9 bits (63), Expect = 0.12
Identities = 104/510 (20%), Positives = 184/510 (36%), Gaps = 89/510 (17%)
Query 317 EKGLGVSNAGTIRAVNNLVVTSAGKIEHKG-----SLESTSNT-----QGLVSIQTTQTG 366
+ GL V+ +GT+ + N VTSA + + +L++T G + + TG
Sbjct 2386 KSGLTVALSGTVGSAINNAVTSAQETKESSDSRLKALQATKTALSGVQAGQAATMASATG 2445
Query 367 DNGNINSSGSITSKSMLSIDAANHLNITGNQVIVNQGVVSPLLLSAQGDINVSNGAII-- 424
D S S+T++ S + ++G+ + + +GD + G I+
Sbjct 2446 DPNATGVSLSLTTQKSKSQQHSESDTVSGSTLNAGNNLSVVATGKNRGD---NRGDIVIA 2502
Query 425 -KNVQTGGDIYLDAQN---INVGENTQIANVGLVNLNAAAAIDIKKSARVKAVNDLNIIA 480
++ GG+ LDA N ++ NTQ + + I N I
Sbjct 2503 GSQLKVGGNTSLDAANDILLSGAANTQKTTGRNSSSGGGVGVSIGAGG-----NGAGISV 2557
Query 481 KQGLSVADANLVAEKGNMNLQSNSNITLQGTTLDLT--KDLNINGT---GNVNLSSLNFS 535
G++ A + EKGN + T G T+ + +D +NG GN ++ +
Sbjct 2558 FAGVNAAKGS---EKGN-GTEWTETTTDSGKTVTINSGRDTVLNGAQVNGNRIIADVGHD 2613
Query 536 LLNGSSTLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANLIDLKGSNLSGKGDLKLQG 595
LL S Q+ + Y QT+ A ++ + I + + D +
Sbjct 2614 LLISSQ--QDTSKYDS-----KQTSVAAGGSFTFGSMTGSGYIAASRDKMKSRFDSVAEQ 2666
Query 596 KAL---NVGADLTAGKSLNLTATQSDLILNKTLNAQGNIDIASLDGKLNATGLNATSSQG 652
+ + G D+T G+ L +I + + ++D G L + L+ +
Sbjct 2667 TGMFAGDGGFDITVGRHTQLDGA---VIASTATPDKNHLDT----GTLGFSDLH-NEADY 2718
Query 653 KLSIFGAKDTVLTNSGTVKTTLKGNQGVNVGTISTGNLTLQNTVLESQNGAIVVTSEGQN 712
K+S G L+ G+ +GN + G IS G G
Sbjct 2719 KVSHSGIS---LSGGGSFGDKFQGN--MPGGMISAGG------------------HSGHA 2755
Query 713 TLTDSIITAKGNIELFAKDNLTLDGIKSSSQQHTALNSKKNIYINSQAGTGDSVNFSSTK 772
T A+G I + +DN Q+ N ++ A T DS++ K
Sbjct 2756 EGTTQAAVAEGTITIRDRDN----------QKQNLANLSRD-----PAHTNDSISPIFDK 2800
Query 773 ITELNSTGTLSLISDKNQNLQNTRLTGGAI 802
E T+ LISD + + T G +
Sbjct 2801 EKEQRRLQTVGLISDIGSQVADIARTQGEL 2830
Score = 26.6 bits (57), Expect = 0.61
Identities = 66/295 (22%), Positives = 119/295 (40%), Gaps = 45/295 (15%)
Query 1557 ASVSLINNGGDLG-KTLKDLGSKDSVKNLAASVVTAGL---LSQVGSALNLKPDTSGFSA 1612
A ++ N+G + + L S + NL A +++AG LS +G N+ SG +
Sbjct 1864 AGGNITNSGSSINAQNGLSLDSTGYIDNLNAGLISAGGSLDLSAIGDISNISSVISGKTV 1923
Query 1613 RLLNNFTTAVGSTLVQTAIKGGDLEDNLKVALLAGLAGAMQGELASQIGTHLDKVDPNVF 1672
+L + T Q G D L+G G +A+ GT +D
Sbjct 1924 QLESVSGNISNITRRQQWNAGSDSRYGG-----VHLSGTDTGPVATIKGTDSLSLD---- 1974
Query 1673 EYAIHKIAHAAVGCAVAAATKSSCEAGAIGAGVGE---IVASLMPDPVN--GIEYNEDEK 1727
A + AT SS G +G G I A+L+ + G + +D
Sbjct 1975 ---------AGKNIDITGATVSS--GGTLGMSAGNDINIAANLISGSKSQSGFWHTDDNS 2023
Query 1728 ---TKIRNTGKIVAGVVSAYAGYDVNTAANSADIAIQNNSLVKLATSTGKILVKTLDEFN 1784
T + + G ++ AG++++ A+S ++ +++L+ S G L N
Sbjct 2024 ASSTTSQGSSISAGGNLAMAAGHNLDVTASS--VSAGHSALL----SAGNDL-----SLN 2072
Query 1785 ALRKAGKQVTKDDLVTSFKKQGADELIGIADDLLTVFGRSSSSFDRALAAIDLIV 1839
A+R++ +++ S + A + D+LL V GR +S +AA + +V
Sbjct 2073 AVRESKN--SRNGRSESHESHAAVSTVTAGDNLLLVAGRDVASQAAGVAAENNVV 2125
Score = 23.1 bits (48), Expect = 6.9
Identities = 21/83 (25%), Positives = 34/83 (41%), Gaps = 12/83 (14%)
Query 1198 SNQDNLVLQATGITAANGDVRIEANKNILFDAAIEQSYDRSTTTEKKSSWGGLKK----K 1253
S LV A +T V ++ N++ D+A S+T ++S GG
Sbjct 508 SGAKELVASADTLTTTEKSVT-NSDGNLMLDSA-------SSTLAGETSAGGTVSVKGNS 559
Query 1254 YITTVSENNQANAASVDISGKNI 1276
TT + Q N+ SVD+ +
Sbjct 560 LKTTTTAQTQGNSVSVDVQNAQL 582
>P0DSI1 tRNA nuclease CdiA [Escherichia coli (strain NC101)]
Length=3289
Score = 221 bits (563), Expect = 5e-60
Identities = 253/876 (29%), Positives = 399/876 (46%), Gaps = 128/876 (15%)
Query 85 PVIGVGQNSQGQNVPVVNIQTPTN-GVSHNIYKQMDVLPEGVVLNNSRTGAN-SSLVGTV 142
P G G + VPVVNI TP G+SHN + +V EG++LNN+ N + L G +
Sbjct 36 PQNGAGMDKAANGVPVVNIATPDGAGISHNRFTDYNVGKEGLILNNATGKLNPTQLGGLI 95
Query 143 GANPFL-AKGEARIILNEVNSSVASRFEGNLEVAGQRADVIIANPAGINIKGGGFINANK 201
NP L A GEA+ I+NEV S +G EVAG+ A+V++ANP GI G GFIN
Sbjct 96 QNNPNLKAGGEAKGIINEVTGGNRSLLQGYTEVAGKAANVMVANPYGITCDGCGFINTPH 155
Query 202 AILTTGKPQLNADGSIQQFVVDQGKITISANSGSSLGLGGNKNNADYVDLYARALELNAQ 261
A LTTG+P +NADGS+Q V +G ITI+ G G + +D V + ARA E+NA
Sbjct 156 ATLTTGRPVMNADGSLQALEVTEGSITIN-------GAGLDGTRSDAVSIIARATEVNAA 208
Query 262 LYANKDIQAITGANNISADLQQISTRTGTGTTPTLAIDVKNLGGMYANNIYLLGNEKGLG 321
L+A KD+ GAN I+AD ++S G G P +A+D LGGMYA I+L E G+G
Sbjct 209 LHA-KDLTVTAGANRITAD-GRVSALKGEGDVPKVAVDTGALGGMYARRIHLTSTESGVG 266
Query 322 VSNAGTIRAVNNLVVTSAGKIEHKGSLES---TSNTQGLVSIQTTQTGDN---GNINSSG 375
V+ ++ + ++G++ SL + T+ QG+ T TGD+ GN+
Sbjct 267 VNLGNLYARDGDITLDASGRLTVNNSLATGAVTAKGQGV-----TLTGDHKAGGNL---- 317
Query 376 SITSKSMLSIDAANHLNITGNQVIVNQGVVS---PLLLSAQGDINVSNGAIIKNVQTGGD 432
S++S+S ++++ G ++ L L+A G I N + + G D
Sbjct 318 SVSSRS---------------DIVLSNGTLNSDKDLSLTAGGRITQQN----EKLTAGRD 358
Query 433 IYLDAQNINVGENTQIANVGLVNLNAAAAIDIKKSARVKAVNDL----NIIAKQGLSVAD 488
+ L A+NI +QI NAA I S + + N+ A D
Sbjct 359 VTLAAKNITQDTASQI--------NAARDIVTVSSDTLTTQGQITAGQNLTASATTLTQD 410
Query 489 ANLVAEKGNMNLQS---NSNITLQGTTLDLTKDLNINGTGNVNLSSLNFSLLNGSSTLQN 545
L+A KG+ L + N++ +QG +L L G+ LS+ + SLL+G N
Sbjct 411 GTLLA-KGHAGLDAGTLNNSGAVQGASLTL---------GSTTLSN-SGSLLSGGPLTVN 459
Query 546 INAY-----SGLNLVWDQTAKALPQISGNVTLEAANLIDLKGSNLSGKGDLKLQGKALNV 600
+ +G D TA +++ +L + +++ LK +++ G L GK L V
Sbjct 460 TRDFTQSGRTGAKGKVDITASG--KLTSTGSLVSDDVLVLKAQDVTQNGVLS-GGKGLTV 516
Query 601 GADLTAGKSLNLTATQSDLILNKTL------NAQGNIDIASLDGKLNATGLNATSSQGKL 654
A + ++T + + + LN T N+ G D + +T A GK
Sbjct 517 SAQALSSGKKSVTHSDAAMTLNVTTVALDGENSAG--DTLRVQADKLSTAAGAQLQSGKN 574
Query 655 SIFGAKDTVLTNSGTVKTTLKGNQG---VNVGTISTGNLTLQNTVLESQNGAIVVTSEGQ 711
A+D L + + T+ N + G S +L+L L S V+
Sbjct 575 LSINARDARLAGTQAAQQTMAVNASEKLTHSGKSSAPSLSLSAPELTSSG---VLVGSAL 631
Query 712 NTLTDSIITAKGNIELFAKDNLTLDGIKSSSQQHTALNSKKNIYI------NSQAGTGDS 765
NT + + +T G ++ + +LT++ + +QQ+ L S ++ + NS TGD
Sbjct 632 NTQSQT-LTNSGLLQ--GEASLTVNTQRLDNQQNGTLYSAADLTLDIPDIRNSGLITGD- 687
Query 766 VNFSSTKITELNSTGTLSLISDKNQNLQNTRLTGGAILLEAGGTLNTPKVIEFNATGSNL 825
N + L++ G +I+D N++ T L G +L AG + G L
Sbjct 688 -NGLTLNTASLSNPG--KIIAD-TLNVRATTLDGDGLLQGAGALALAGDTLSQGRNGRWL 743
Query 826 LKNDSKLNSLNGDLSIQTK-ESLTID----PNIHTLKAIGDIELASKQGTLILAGYGGQA 880
D L + T+ ++LT+ N ++ A G++ AS G L G
Sbjct 744 TAGDLSLRGKTLHTAGTTQGQNLTVQADNWANSGSVLATGNL-TASATGQLTST---GDI 799
Query 881 GNGSEKVLNLTTT--------GGGISLEGASVELQG 908
+ + LN TT G +SL+G S++ +G
Sbjct 800 MSQGDTTLNAATTDNRGSLLSAGTLSLDGNSLDNRG 835
Score = 80.1 bits (196), Expect = 4e-17
Identities = 209/930 (22%), Positives = 352/930 (38%), Gaps = 138/930 (15%)
Query 76 DNSANAGNRPVIGVGQNS--QGQ-NVPVVNIQTPTNGVSHNIYKQMDVLPEGVVLNNSRT 132
D + AG + G+ S +G+ +VP V + T G + + GV +N
Sbjct 213 DLTVTAGANRITADGRVSALKGEGDVPKVAVDTGALGGMYARRIHLTSTESGVGVNLGNL 272
Query 133 GANSSLV-----GTVGANPFLAKGEARIILNEVNSSVASRFEGNLEVAGQRADVIIANPA 187
A + G + N LA G V + + GNL V+ R+D++++N
Sbjct 273 YARDGDITLDASGRLTVNNSLATGAVTAKGQGVTLTGDHKAGGNLSVSS-RSDIVLSNGT 331
Query 188 -----GINIKGGGFINANKAILTTGKPQLNADGSIQQFVVDQGKIT--ISANSGSSLGLG 240
+++ GG I LT G+ A +I Q Q I S +L
Sbjct 332 LNSDKDLSLTAGGRITQQNEKLTAGRDVTLAAKNITQDTASQINAARDIVTVSSDTLTTQ 391
Query 241 GNKNNADYVDLYARALELNAQLYANKDIQAITGANNISADLQQISTRTGTGTTPTLAIDV 300
G + A L + L A G N S +Q S G+ T +
Sbjct 392 GQITAGQNLTASATTLTQDGTLLAKGHAGLDAGTLNNSGAVQGASLTLGSTT-------L 444
Query 301 KNLGGMYANNIYLLGNEKGLGVSNAGTIRAVNNLVVTSAGKIEHKGSLESTSNTQGLVSI 360
N G + + + + +G A + +T++GK+ GSL S + L +
Sbjct 445 SNSGSLLSGGPLTVNTRD---FTQSGRTGAKGKVDITASGKLTSTGSLVS-DDVLVLKAQ 500
Query 361 QTTQ----TGDNGNINSSGSITS--KSMLSIDAANHLNITGNQVIVNQGVVSPLLLSAQG 414
TQ +G G S+ +++S KS+ DAA LN+T + L + A
Sbjct 501 DVTQNGVLSGGKGLTVSAQALSSGKKSVTHSDAAMTLNVTTVALDGENSAGDTLRVQAD- 559
Query 415 DINVSNGAIIKNVQTGGDIYLDAQNINVGENTQIANVGLVNLNAAAAIDIKKSARVKAVN 474
++ + GA +Q+G ++ ++A++ + VN + K SA +++
Sbjct 560 KLSTAAGA---QLQSGKNLSINARDARLAGTQAAQQTMAVNASEKLTHSGKSSAPSLSLS 616
Query 475 DLNIIAKQGLSVADANLVAEKGNMN---LQSNSNITLQGTTLDLTKDLNINGTGNVNLSS 531
+ + G+ V A + N LQ +++T+ LD ++ + ++ L
Sbjct 617 APELTSS-GVLVGSALNTQSQTLTNSGLLQGEASLTVNTQRLDNQQNGTLYSAADLTLDI 675
Query 532 ---LNFSLLNGSS--TLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANLIDLKGSNLS 586
N L+ G + TL + + ++ D + G+ L+ A + L G LS
Sbjct 676 PDIRNSGLITGDNGLTLNTASLSNPGKIIADTLNVRATTLDGDGLLQGAGALALAGDTLS 735
Query 587 G--------KGDLKLQGKALNVGADLTAGKSLNLTATQSDLILNKTLNAQGNIDIASLDG 638
GDL L+GK L+ A T G+ NLT + + ++ A GN+ AS G
Sbjct 736 QGRNGRWLTAGDLSLRGKTLHT-AGTTQGQ--NLTVQADNWANSGSVLATGNLT-ASATG 791
Query 639 KLNATG---------LNATSSQGKLSIFGA-----KDTVLTNSGTVK---TTLKGNQGVN 681
+L +TG LNA ++ + S+ A L N GTV+ T++ N N
Sbjct 792 QLTSTGDIMSQGDTTLNAATTDNRGSLLSAGTLSLDGNSLDNRGTVQGNHVTIRQNSVTN 851
Query 682 VGT---ISTGNLTLQNTVLESQ-----NGAIVVTSEGQNTLTDSIITAKGNIE----LFA 729
GT I+ L + + Q NG ++TS G T+T IT+ G+ + L
Sbjct 852 SGTLTGIAALTLAARMDMASPQPALMNNGGSLLTS-GDLTITAGSITSSGHWQGKQVLIT 910
Query 730 KDNLTLDGIKSSSQQHTALNSKKNIYINSQAGTGDSVNFSSTKITELNSTGTLSLISDKN 789
D+L G ++ TA TG+ V+ + +K+T
Sbjct 911 ADSLANSGAIQAADSLTARL------------TGELVSTAGSKVT--------------- 943
Query 790 QNLQNTRLTGGAILLEAGGTLNTPKVIEFNATGSNLLKNDSKLNSLNGDLSIQTKESLTI 849
+ G + L A N+ + I N T K NSL I ++LT+
Sbjct 944 --------SNGEMALSALNLSNSGQWIAKNLT--------LKANSLTSAGDITGVDALTL 987
Query 850 DPNIHTLKAIGDIELASKQGTLILAGY-----GGQAGNGSEKVLNLTTTGGGISLEGASV 904
N TL +L S G L L G GN + T GG + E ++
Sbjct 988 TVN-QTLNNHASGKLLSA-GVLTLKADSVKNDGQLQGNATTITAGQLTNGGHLQGETLTL 1045
Query 905 ELQGAQLNAEKNIKILANNENIQIISIKNK 934
G N + + N N+ ++ N+
Sbjct 1046 TASGGVNNRSGGVLMSRNALNVSTATLSNQ 1075
Score = 76.6 bits (187), Expect = 4e-16
Identities = 187/938 (20%), Positives = 357/938 (38%), Gaps = 155/938 (17%)
Query 344 HKGSLESTSNTQGLVSIQTTQTGDNGNI-NSSGSITSKSMLSIDAANHLNITGNQVIVNQ 402
H GS+ S +N Q GNI NS GSI +++ LS+D+ +++ +N
Sbjct 1873 HNGSVISGNNVQLA----------GGNITNSGGSINAQNGLSLDSTGYID------NLNA 1916
Query 403 GVVS---PLLLSAQGDI----NVSNGAIIKNVQTGGDI--YLDAQNINVGENTQIANVGL 453
G++S L LSA GDI +V +G ++ G+I Q N G +++ V L
Sbjct 1917 GLISAGGSLDLSAIGDISNISSVISGKTVQLESVSGNISNITRRQQWNAGSDSRYGGVHL 1976
Query 454 ----------------VNLNAAAAIDIKKSARVKAVNDLNIIAKQGLSVADANLV----A 493
++L+A IDI A V + L + A +++A ANL+ +
Sbjct 1977 SGTDTGPVATIKGTDSLSLDAGKNIDI-TGATVSSGGTLGMSAGNDINIA-ANLISGSKS 2034
Query 494 EKGNMNLQSN--SNITLQGTTLDLTKDLNINGTGNVNLSSLNFSLLNGSSTLQNINAYSG 551
+ G + N S+ T QG+++ +L + N+++++ + S G S L +
Sbjct 2035 QSGFWHTDDNSASSTTSQGSSISAGGNLAMAAGHNLDVTASSVSA--GHSALLSAGNDLS 2092
Query 552 LNLVWDQTAKALPQISGNVTLEAANLIDLKGSNLSGKGDLKLQGKALNVGAD----LTAG 607
LN V + + + + A + + G NL + +A V A+ + G
Sbjct 2093 LNAVRESKNSRNGRSESHESHAAVSTV-TAGDNLLLVAGRDVASQAAGVAAENNVVIRGG 2151
Query 608 KSLNLTA----------TQSDLILNKTLNAQGNIDIASLDGKLNA-----TGLNATSSQG 652
+ +NL A ++ +N+T+ QG + D +NA ++ ++ G
Sbjct 2152 RDVNLVAESAGAGDSYTSKKKKEINETVRQQGTEIASGGDTTVNAGRDITAVASSVTATG 2211
Query 653 KLSIFGAKDTVLTNSGTVKTTLKGNQGVNVGTISTGNLTLQNTVLESQNGAIVVTSEGQN 712
+S+ +D LT + T + S G L+ + T S++ A + E +
Sbjct 2212 NISVNAGRDVALTTA-----TESDYHYLETKKKSGGFLSKKTTHTISEDSA---SREAGS 2263
Query 713 TLTDSIITAKGNIELFAKDNLTLDGIKSSSQQHTALNSKKNIYINSQAGTGDSVNFSSTK 772
L+ + +T A DNLT++G + Q +L + ++ + + T S F TK
Sbjct 2264 LLSGNRVTVN------AGDNLTVEGSDVVADQDVSLAAGNHVDVLAATSTDTSWRFKETK 2317
Query 773 ITELNSTGTLSLISDKNQNLQNTRLTGGAILLEAGGTLNTPKVIEFNATGSNLLKNDSKL 832
+ L TG + ++ + R GT + +T N+ K
Sbjct 2318 KSGLMGTGGIGFTIGSSKTTHDRR---------EAGTTQSQSASTIGSTAGNVSITAGKQ 2368
Query 833 NSLNG-------DLSIQTKESLTIDPNIHTLKAIGDIELASKQG-TLILAGYGGQAGNGS 884
++G D+SI T +S+ +DP H + + + K G T+ L+G G A N +
Sbjct 2369 AHISGSDVIANRDISI-TGDSVVVDPG-HDRRTVDEKFEQKKSGLTVALSGTVGSAINNA 2426
Query 885 EKVLNLTTTGGGI---SLEGASVELQGAQLNAEKNIKILANNENIQIISIK---NKLNNS 938
T +L+ L G Q + + N +S+ K +
Sbjct 2427 VTSAQETKESSDSRLKALQATKTALSGVQAGQAAAMATATGDPNATGVSLSLTTQKSKSQ 2486
Query 939 KLSDSNKLLVDLVEIDNKLKKISINNQYTELFLADVKILENAYDIAFNFNPSAYKEDASY 998
+ S+S+ + + N L ++ +N DI +
Sbjct 2487 QHSESDTVSGSTLNAGNNLSVVATGKNRG----------DNRGDIVI--------AGSQL 2528
Query 999 RKGSDKDIQFFNEVYDGFVKKYSDIIEPNIYSQQLNGTKYSTQISIAVPFGDGDYARKED 1058
+ G + + N+V ++ +Q+ G S+ + V G G
Sbjct 2529 KAGGNTSLDAANDV----------LLSGAANTQKTTGRNSSSGGGVGVSIGAGGNGAGIS 2578
Query 1059 ILSPNGYFKYKYDQNKIRSEINYLSQLNGYEHFSSKLVSNSGSIDITSSKGISISGSELI 1118
+ + K + NG E ++ + + ++ I S + ++G+++
Sbjct 2579 VFASVNAAKGS-------------EKGNGTE-WTETTIDSGKTVTINSGRDTVLNGAQVN 2624
Query 1119 SKKGLVNI-EALGALSQNYTSTIHGKDNKPKTLGASIIIDGSQDFYDKGNENDQKYRFRT 1177
+ + ++ L SQ TS K G+ + Y + + K RF +
Sbjct 2625 GNRIIADVGHDLLISSQQDTSKYDSKQTSVAAGGSFTFGSMTGSGYIAASRDKMKSRFDS 2684
Query 1178 ILKPT-LINGDKGVTIRATGNSNQDNLVLQATGITAAN 1214
+ + T + +GD G I ++ D V+ +T N
Sbjct 2685 VAEQTGMFSGDGGFDITVGNHTQLDGAVIASTATADKN 2722
Score = 72.8 bits (177), Expect = 6e-15
Identities = 167/830 (20%), Positives = 329/830 (40%), Gaps = 127/830 (15%)
Query 185 NPAGINIKGGGFINANKAILTTGKPQLNADGSIQQFVVDQGKITISANSGSSLGLGGNKN 244
+P I + G I+ N L G N+ GSI +A +G SL G
Sbjct 1866 SPEDITLHNGSVISGNNVQLAGGNIT-NSGGSI------------NAQNGLSLDSTG--- 1909
Query 245 NADYVDLYARALELNAQLYA---NKDIQAITGANNISADLQ----QISTRTGTGTTPTLA 297
Y+D LNA L + + D+ AI +NIS+ + Q+ + +G + T
Sbjct 1910 ---YID------NLNAGLISAGGSLDLSAIGDISNISSVISGKTVQLESVSGNISNITRR 1960
Query 298 IDVKNLGGMYANNIYLLGNEKGLGVSNAGTIRAVNNLVVTSAGKIEHKGSLESTSNTQG- 356
++L G + G TI+ ++L + + I+ G+ S+ T G
Sbjct 1961 QQWNAGSDSRYGGVHLSGTDTG----PVATIKGTDSLSLDAGKNIDITGATVSSGGTLGM 2016
Query 357 -----------LVSIQTTQTG----DNGNINSS----GSITSKSMLSIDAANHLNITGNQ 397
L+S +Q+G D+ + +S+ SI++ L++ A ++L++T +
Sbjct 2017 SAGNDINIAANLISGSKSQSGFWHTDDNSASSTTSQGSSISAGGNLAMAAGHNLDVTASS 2076
Query 398 VIVNQGVVSPLLLSAQGDINVSNGAIIKNVQTGG----DIYLDAQNINVGENTQIANVGL 453
V LLSA D++++ KN + G + + + G+N + G
Sbjct 2077 VSAGHSA----LLSAGNDLSLNAVRESKNSRNGRSESHESHAAVSTVTAGDNLLLV-AGR 2131
Query 454 VNLNAAAAIDIKKSARVKAVNDLNIIAKQGLSVADANLVAEKGNMNLQSNSNITLQGTTL 513
+ AA + + + ++ D+N++A+ D+ +K +N + QGT +
Sbjct 2132 DVASQAAGVAAENNVVIRGGRDVNLVAESA-GAGDSYTSKKKKEIN----ETVRQQGTEI 2186
Query 514 DLTKDLNINGTGNVNLSSLNFSLLNGSSTLQNINAYSGLNLVWDQTAKALPQISGNVTLE 573
D +N ++ ++ + + NI+ +G ++ TA +
Sbjct 2187 ASGGDTTVNAGRDIT------AVASSVTATGNISVNAGRDVALT-TATESDYHYLETKKK 2239
Query 574 AANLIDLKGSNLSGKGDLKLQGKALNVGADLTAGKSLNLTATQSDLILNK--TLNAQGNI 631
+ + K ++ + + +L G +T NLT SD++ ++ +L A ++
Sbjct 2240 SGGFLSKKTTHTISEDSASREAGSLLSGNRVTVNAGDNLTVEGSDVVADQDVSLAAGNHV 2299
Query 632 DIASLDGKLNATGLNATSSQGKLSIFGAKDTVLTNSGTVKTTLKGN-QGVNVGTIST--G 688
D+ + + T G + G T+ ++ T G Q + TI + G
Sbjct 2300 DVLAATSTDTSWRFKETKKSGLMGTGGIGFTIGSSKTTHDRREAGTTQSQSASTIGSTAG 2359
Query 689 NLTLQNTVLESQNGAIVVTSEGQNTLTDSIITAKGNI-----ELFA--KDNLTL------ 735
N+++ +G+ V+ + + DS++ G+ E F K LT+
Sbjct 2360 NVSITAGKQAHISGSDVIANRDISITGDSVVVDPGHDRRTVDEKFEQKKSGLTVALSGTV 2419
Query 736 ------------DGIKSSSQQHTALNSKKNIYINSQAGTGDSVNFSSTKITELNSTG-TL 782
+ +SS + AL + K QAG ++ +T + N+TG +L
Sbjct 2420 GSAINNAVTSAQETKESSDSRLKALQATKTALSGVQAGQAAAM---ATATGDPNATGVSL 2476
Query 783 SLISDKNQNLQNTRLTGGAILLEAGGTLNTPKVIEFNATGSNLLKNDSKLNSLNGDLSIQ 842
SL + K+++ Q++ +G TLN + ATG N + D++ GD+ I
Sbjct 2477 SLTTQKSKSQQHSESD-----TVSGSTLNAGNNLSVVATGKN--RGDNR-----GDIVIA 2524
Query 843 TKESLTIDPNIHTLKAIGDIELASKQGTLILAGYGGQAGNGSEKVLNLTTTGGGISLEGA 902
+ L N +L A D+ L+ T G +G G + G GIS+ +
Sbjct 2525 GSQ-LKAGGNT-SLDAANDVLLSGAANTQKTTGRNSSSGGGVGVSIGAGGNGAGISVFAS 2582
Query 903 SVELQGAQL--NAEKNIKILANNENIQIISIKNKLNNSKLSDSNKLLVDL 950
+G++ E + + + + I S ++ + N + N+++ D+
Sbjct 2583 VNAAKGSEKGNGTEWTETTIDSGKTVTINSGRDTVLNGAQVNGNRIIADV 2632
Score = 70.5 bits (171), Expect = 3e-14
Identities = 143/648 (22%), Positives = 253/648 (39%), Gaps = 123/648 (19%)
Query 323 SNAGTIRAVNNLVVTSAGKIEHKGSLESTSNTQGLVSIQTTQTGDNGNINSSGSITSKSM 382
+N+G++ A NL ++ G++ G + S QG ++ T + G++ S+G+++
Sbjct 774 ANSGSVLATGNLTASATGQLTSTGDIMS----QGDTTLNAATTDNRGSLLSAGTLSLDGN 829
Query 383 LSID-----AANHLNITGNQVIVNQGV---VSPLLLSAQGDINVSNGAIIKN---VQTGG 431
S+D NH+ I N V N G ++ L L+A+ D+ A++ N + T G
Sbjct 830 -SLDNRGTVQGNHVTIRQNSV-TNSGTLTGIAALTLAARMDMASPQPALMNNGGSLLTSG 887
Query 432 DIYLDAQNINVGENTQIANVGLVNLNAAAAIDIKKSARVKAVNDLNIIAKQGLSVADANL 491
D+ + A +I + Q V + A + S ++A + L L +
Sbjct 888 DLTITAGSITSSGHWQGKQVLIT------ADSLANSGAIQAADSLTARLTGELVSTAGSK 941
Query 492 VAEKGNMNLQSNSNITLQGTTLDLTKDLNINGTGNVNLSSLNFSLLNGSSTLQNINAYSG 551
V G M L + LN++ +G +L N ++ +I
Sbjct 942 VTSNGEMALSA----------------LNLSNSGQWIAKNLTLKA-NSLTSAGDITGVDA 984
Query 552 LNLVWDQTAKALPQISGNVTLEAANLIDLKGSNLSGKGDLKLQGKALNVGADLTAGKSLN 611
L L +QT SG L +A ++ LK ++ K D +LQG A + TAG+ N
Sbjct 985 LTLTVNQTLNN--HASGK--LLSAGVLTLKADSV--KNDGQLQGNATTI----TAGQLTN 1034
Query 612 LTATQSDLILNKTLNAQGNIDIASLDGKLNATGLNATSSQGKLSIFGAKDTVLTNSGTVK 671
Q + + TL A G ++ S ++ LN +++ L+N GT++
Sbjct 1035 GGHLQGETL---TLTASGGVNNRSGGVLMSRNALNVSTA------------TLSNQGTIQ 1079
Query 672 TTLKGNQGVNVGT----------ISTGNLTLQNTVLESQNGAIVVTS----EGQNTLTDS 717
G GV++ +S NLTL VL + +V + + NT+
Sbjct 1080 ----GGGGVSLNATDRLQNDGKILSGSNLTLTAQVLANTGSGLVQAATLLLDVVNTVNGG 1135
Query 718 IITAKGNIELFA---KDNLTLDGIKSSSQQHTALNSKKNIYINSQAGTGDSVNFSSTKIT 774
+ A G+ ++ + TL G HT NS + + G S+ + T
Sbjct 1136 RVLATGSADVKGTTLNNTGTLQGADLLVNYHTFSNSGTLLGTSGLGVKGSSLLQNGTG-- 1193
Query 775 ELNSTGTLSLISDKNQNLQNTRLTGGAIL-----LEAGGTLNTPKVIEFNA----TGSNL 825
L S G L L + TG L L GTL K + + T +
Sbjct 1194 RLYSAGNLLLDAQDFSGQGQVVATGDVTLKLIAALTNHGTLAAGKTLSVTSQNAITNGGV 1253
Query 826 LKNDSKLNSL------NGDLSIQTKESLTIDPNIH-----TLKAIGDIELASKQGTLILA 874
++ D+ + NG L+ S+ + +L+A GD+ L S+ + ++
Sbjct 1254 MQGDAMVLGAGEAFTNNGMLTAGKGNSVFSAQRLFLNAPGSLQAGGDVSLNSRSD-ITIS 1312
Query 875 GYGGQAGNGSEKVLNLTTTGGGISLEGASVELQGAQLNAEKNIKILAN 922
G+ G T G +++ A L A + A N+K+ +
Sbjct 1313 GFTG--------------TAGSLTMNVAGTLLNSALIYAGNNLKLFTD 1346
Score = 69.3 bits (168), Expect = 7e-14
Identities = 176/750 (23%), Positives = 288/750 (38%), Gaps = 150/750 (20%)
Query 73 IQADNSANAGNRPVIGVGQNSQGQNVPVVNIQTPTNGVSHNIYKQMDVLPEG-VVLNNSR 131
+QADN AN+G+ V+ G N+ G + D++ +G LN +
Sbjct 768 VQADNWANSGS--VLATG-----------NLTASATG---QLTSTGDIMSQGDTTLNAAT 811
Query 132 TGANSSLVGTVGANPFLAKGEARIILNEVNSSVASRFEGNLEVAGQRADVIIANPAGINI 191
T SL L+ G + N +++ +GN Q + GI
Sbjct 812 TDNRGSL---------LSAGTLSLDGNSLDN--RGTVQGNHVTIRQNSVTNSGTLTGI-- 858
Query 192 KGGGFINANKAILTTGKPQLNADGSIQQFVVDQGKITISANSGSSLGLGGNKNNADYVDL 251
A + + + +P L +G ++ G +TI+A S +S G K
Sbjct 859 --AALTLAARMDMASPQPALMNNGG---SLLTSGDLTITAGSITSSGHWQGKQ------- 906
Query 252 YARALELNAQLYANKDIQAITGANNISADL--QQISTR----TGTGTTPTLAIDVKNLGG 305
+ + A AN AI A++++A L + +ST T G A+++ N G
Sbjct 907 ----VLITADSLANSG--AIQAADSLTARLTGELVSTAGSKVTSNGEMALSALNLSNSGQ 960
Query 306 MYANNIYLLGNEKGLGVSNAGTIRAVNNLVVT--------SAGKIEHKGSL----ESTSN 353
A N+ L N +++AG I V+ L +T ++GK+ G L +S N
Sbjct 961 WIAKNLTLKAN----SLTSAGDITGVDALTLTVNQTLNNHASGKLLSAGVLTLKADSVKN 1016
Query 354 TQGLVSIQTTQTGDNGNINSSGSITSKSMLSIDAANHLNITGNQVIVNQGV--VSPLLLS 411
L TT T G + + G + ++ L++ A+ +N V++++ VS LS
Sbjct 1017 DGQLQGNATTITA--GQLTNGGHLQGET-LTLTASGGVNNRSGGVLMSRNALNVSTATLS 1073
Query 412 AQGDINVSNGAIIK---NVQTGGDIYLDAQNINVGENTQIANVGLVNLNAAA-AIDIKKS 467
QG I G + +Q G I L N+ + +AN G + AA +D+
Sbjct 1074 NQGTIQGGGGVSLNATDRLQNDGKI-LSGSNLTLTAQV-LANTGSGLVQAATLLLDV--- 1128
Query 468 ARVKAVNDLNIIAKQGLSVADANLVAEKGNMNLQSNSNITLQGTTLDLTKDLNINGTGNV 527
V VN ++A V L N+ TLQG L + N +
Sbjct 1129 --VNTVNGGRVLATGSADVKGTTL-----------NNTGTLQGADLLVNYHTFSNSGTLL 1175
Query 528 NLSSLNFSLLNGSSTLQNINA--YSGLNLVWDQ---------------TAKALPQISGNV 570
S L + GSS LQN YS NL+ D T K + ++ +
Sbjct 1176 GTSGLG---VKGSSLLQNGTGRLYSAGNLLLDAQDFSGQGQVVATGDVTLKLIAALTNHG 1232
Query 571 TLEAANLIDLKGSNLSGKGDLKLQGKALNVGAD--------LTAGKSLNLTATQSDLILN 622
TL A + + N G + +QG A+ +GA LTAGK ++ + Q L LN
Sbjct 1233 TLAAGKTLSVTSQNAITNGGV-MQGDAMVLGAGEAFTNNGMLTAGKGNSVFSAQR-LFLN 1290
Query 623 KTLNAQGNIDIASLDGKLNATGLNATSSQGKLSIFGAKDTVLTNSGTVKTTLKGNQGVNV 682
G L A G + +S+ ++I G T + + V TL + +
Sbjct 1291 -------------APGSLQAGGDVSLNSRSDITISGFTGTAGSLTMNVAGTLLNSALIYA 1337
Query 683 GTISTGNLTLQNTVLESQNGAIV------VTSEGQNTLTDSIITAKGNIELFAKDNLTLD 736
G NL L L +Q+G I+ V + II GNIE D +
Sbjct 1338 G----NNLKLFTDRLHNQHGDILAGNSLWVQKDASGGANTEIINTSGNIETHQGDIVVRT 1393
Query 737 GIKSSSQQHTALNSKKNIYINSQAGTGDSV 766
G + ++ + + +S G G+++
Sbjct 1394 GHLLNQREGFSATTTTRTNPSSIQGMGNAL 1423
Score = 68.9 bits (167), Expect = 9e-14
Identities = 207/921 (22%), Positives = 355/921 (39%), Gaps = 182/921 (20%)
Query 1 MNKNRYRVVYNQARQMFMAVAENVKSQTKTSGQSTASSVTVEQSQPFHQLWQVKCLVASM 60
+N R+ QA Q MAV N + SG+S+A S+++ S P +L LV S
Sbjct 577 INARDARLAGTQAAQQTMAV--NASEKLTHSGKSSAPSLSL--SAP--ELTSSGVLVGSA 630
Query 61 SLWMPLAPVYAQIQADNSANAGNRPVIGVGQNSQGQNVPVVNIQTPTNGVSHNIYKQMDV 120
Q+ N+G QG+ VN Q N + +Y D+
Sbjct 631 ----------LNTQSQTLTNSGLL---------QGEASLTVNTQRLDNQQNGTLYSAADL 671
Query 121 LPEGVVLNNSR--TGANSSLVGTVG-ANPFLAKGEARIILNEVNSSVASRF-EGNLEVAG 176
+ + NS TG N + T +NP +II + +N + +G L+ AG
Sbjct 672 TLDIPDIRNSGLITGDNGLTLNTASLSNP------GKIIADTLNVRATTLDGDGLLQGAG 725
Query 177 QRA---DVIIANPAGINIKGGGFINANKAILTTGKPQ-----LNADGSIQQ-FVVDQGKI 227
A D + G + G K + T G Q + AD V+ G +
Sbjct 726 ALALAGDTLSQGRNGRWLTAGDLSLRGKTLHTAGTTQGQNLTVQADNWANSGSVLATGNL 785
Query 228 TISA-----NSGSSLGLGGNKNNADYVD-----LYARALELNAQLYANKDIQAITGANNI 277
T SA ++G + G NA D L A L L+ N+ T N
Sbjct 786 TASATGQLTSTGDIMSQGDTTLNAATTDNRGSLLSAGTLSLDGNSLDNRG----TVQGNH 841
Query 278 SADLQQISTRTGTGT-----TPTLAIDVK-------NLGG---------MYANNIYLLGN 316
Q T +GT T T +D+ N GG + A +I G+
Sbjct 842 VTIRQNSVTNSGTLTGIAALTLAARMDMASPQPALMNNGGSLLTSGDLTITAGSITSSGH 901
Query 317 EKGLGV-------SNAGTIRAVNNLVVTSAGKIEHKGSLESTSNTQGLVSIQTTQTGDNG 369
+G V +N+G I+A ++L G++ + TSN G +++ ++G
Sbjct 902 WQGKQVLITADSLANSGAIQAADSLTARLTGELVSTAGSKVTSN--GEMALSALNLSNSG 959
Query 370 N-INSSGSITSKSMLS---IDAANHLNITGNQVIVNQGVVSPLLLSAQGDINVSNGAIIK 425
I + ++ + S+ S I + L +T NQ + N S LLSA G + +
Sbjct 960 QWIAKNLTLKANSLTSAGDITGVDALTLTVNQTLNNH--ASGKLLSA-GVLTLK----AD 1012
Query 426 NVQTGGDIYLDAQNINVGENTQIANV--GLVNLNAAAAIDIKKSARVKAVNDLNI----I 479
+V+ G + +A I G+ T ++ + L A+ ++ + + + N LN+ +
Sbjct 1013 SVKNDGQLQGNATTITAGQLTNGGHLQGETLTLTASGGVNNRSGGVLMSRNALNVSTATL 1072
Query 480 AKQGLSVADANLVAEKGNMNLQSNSNITLQGTTLDLTKDLNIN-GTGNVNLSSLNFSLLN 538
+ QG ++ V+ LQ++ I L G+ L LT + N G+G V ++L ++N
Sbjct 1073 SNQG-TIQGGGGVSLNATDRLQNDGKI-LSGSNLTLTAQVLANTGSGLVQAATLLLDVVN 1130
Query 539 GSSTLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANLIDLKGSNLSGKGDLKLQGKAL 598
++G L A D+KG+ L+ G L+
Sbjct 1131 --------------------------TVNGGRVL-ATGSADVKGTTLNNTGTLQ------ 1157
Query 599 NVGADLTAGKSLNLTATQSDLILNKTLNAQGNIDIASLDGKLNATG---LNATSSQGKLS 655
GADL + + + L+ L +G+ + + G+L + G L+A G+
Sbjct 1158 --GADLLV--NYHTFSNSGTLLGTSGLGVKGSSLLQNGTGRLYSAGNLLLDAQDFSGQGQ 1213
Query 656 IFGAKDTVLTNSGTVKTTLKGNQGVNVGTISTG---NLTLQNTVLES--QNGAIVVTSEG 710
+ D L + N GT++ G ++T QN + G +V G
Sbjct 1214 VVATGDVTLKLIAAL---------TNHGTLAAGKTLSVTSQNAITNGGVMQGDAMVLGAG 1264
Query 711 QNTLTDSIITAKGNIELFAKDNLTLDGIKS-SSQQHTALNSKKNIYINSQAGTGDSVNFS 769
+ + ++TA +F+ L L+ S + +LNS+ +I I+ GT S+ +
Sbjct 1265 EAFTNNGMLTAGKGNSVFSAQRLFLNAPGSLQAGGDVSLNSRSDITISGFTGTAGSLTMN 1324
Query 770 STKITELNST-----GTLSLISDKNQNLQNTRLTGGAILL--EAGGTLNTPKVIEFNATG 822
T LNS L L +D+ N L G ++ + +A G NT
Sbjct 1325 VAG-TLLNSALIYAGNNLKLFTDRLHNQHGDILAGNSLWVQKDASGGANT---------- 1373
Query 823 SNLLKNDSKLNSLNGDLSIQT 843
++ + + GD+ ++T
Sbjct 1374 -EIINTSGNIETHQGDIVVRT 1393
Score = 61.6 bits (148), Expect = 1e-11
Identities = 220/1064 (21%), Positives = 408/1064 (38%), Gaps = 176/1064 (17%)
Query 189 INIKGGGFINANKAILTTGKPQLNADGSIQQFVVDQGK-ITISANSGSS----------- 236
++I G + + ++++ L A Q V+ GK +T+SA + SS
Sbjct 475 VDITASGKLTSTGSLVSDDVLVLKAQDVTQNGVLSGGKGLTVSAQALSSGKKSVTHSDAA 534
Query 237 -------LGLGGNKNNADYVDLYARALEL--NAQLYANKDIQA------ITGAN----NI 277
+ L G + D + + A L AQL + K++ + G +
Sbjct 535 MTLNVTTVALDGENSAGDTLRVQADKLSTAAGAQLQSGKNLSINARDARLAGTQAAQQTM 594
Query 278 SADLQQISTRTGTGTTPTLAIDVKNLGGMYANNIYLLG---NEKGLGVSNAGTIRAVNNL 334
+ + + T +G + P+L++ L ++ L+G N + ++N+G ++ +L
Sbjct 595 AVNASEKLTHSGKSSAPSLSLSAPEL----TSSGVLVGSALNTQSQTLTNSGLLQGEASL 650
Query 335 VV-TSAGKIEHKGSLESTSN-TQGLVSIQTTQ--TGDNGNINSSGSITSKSMLSIDAAN- 389
V T + G+L S ++ T + I+ + TGDNG ++ S+++ + D N
Sbjct 651 TVNTQRLDNQQNGTLYSAADLTLDIPDIRNSGLITGDNGLTLNTASLSNPGKIIADTLNV 710
Query 390 -HLNITGNQVIVNQGVVSPLLLSAQGDINVSNGAIIKNVQTGGDIYLDAQNINVGENTQI 448
+ G+ ++ G L+ GD +S G + + T GD+ L + ++ TQ
Sbjct 711 RATTLDGDGLLQGAGA-----LALAGD-TLSQGRNGRWL-TAGDLSLRGKTLHTAGTTQG 763
Query 449 ANVGLVNLNAAAAIDIKKSARVKA-----VNDLNIIAKQGLSVADANLVAEKGNMNLQSN 503
N+ + N A + + + + A + I QG + +A +G+ L S
Sbjct 764 QNLTVQADNWANSGSVLATGNLTASATGQLTSTGDIMSQGDTTLNAATTDNRGS--LLSA 821
Query 504 SNITLQGTTLDLTKDLNINGTGNVNLSSLNFSLLNGSSTLQNINAYSGLNLVWDQTAKAL 563
++L G +LD GT N ++ + + S TL I A + L D A
Sbjct 822 GTLSLDGNSLDN------RGTVQGNHVTIRQNSVTNSGTLTGIAALT-LAARMDM-ASPQ 873
Query 564 PQISGNVTLEAANLIDLKGSNLSGKGDLKLQGKALNVGADLTAGKSLNLTATQSDLILNK 623
P + N G +L GDL + ++ GK + +TA D + N
Sbjct 874 PALMNN------------GGSLLTSGDLTITAGSITSSGHWQ-GKQVLITA---DSLANS 917
Query 624 TLNAQGNIDIASLDGKLNATGLNATSSQGKLSIFGAKDTVLTNSG---TVKTTLKGNQGV 680
+ A L G+L +T + +S G++++ L+NSG TLK N
Sbjct 918 GAIQAADSLTARLTGELVSTAGSKVTSNGEMALSALN---LSNSGQWIAKNLTLKANSLT 974
Query 681 NVGTIS-------TGNLTLQNTVLESQNGAIVVT-------SEGQ-----NTLTDSIITA 721
+ G I+ T N TL N A V+T ++GQ T+T +T
Sbjct 975 SAGDITGVDALTLTVNQTLNNHASGKLLSAGVLTLKADSVKNDGQLQGNATTITAGQLTN 1034
Query 722 KGNIELFAKDNLTLD---GIKSSS----QQHTALNSKKNIYINS---QAGTGDSVNFSST 771
G+++ + LTL G+ + S ALN N Q G G S+N +
Sbjct 1035 GGHLQ---GETLTLTASGGVNNRSGGVLMSRNALNVSTATLSNQGTIQGGGGVSLNATDR 1091
Query 772 KITE--LNSTGTLSLISDKNQNLQNTRLTGGAILLEAGGTLNTPKVIEFNATGSNLLKND 829
+ + S L+L + N + + +LL+ T+N +V+ ATGS D
Sbjct 1092 LQNDGKILSGSNLTLTAQVLANTGSGLVQAATLLLDVVNTVNGGRVL---ATGSA----D 1144
Query 830 SKLNSLNGDLSIQTKESLTIDPNIHTLK----AIGDIELASKQGTLILAGYGGQAGNGSE 885
K +LN ++Q + L N HT +G L K +L+ G G G+
Sbjct 1145 VKGTTLNNTGTLQGADLLV---NYHTFSNSGTLLGTSGLGVKGSSLLQNGTGRLYSAGNL 1201
Query 886 KVLNLTTTGGGISLEGASVELQGAQLNAEKNIKILANNENIQIISIKNKLNNSKLSDSNK 945
+ +G G + V L+ + A N LA + + + S +N + N + +
Sbjct 1202 LLDAQDFSGQGQVVATGDVTLK--LIAALTNHGTLAAGKTLSVTS-QNAITNGGVMQGDA 1258
Query 946 LLVDLVEIDNKLKKISINNQYTELFLADVKILENAYDIAFNFNPSAYKEDASYRKGSDKD 1005
+++ E F + + + F+ S + G D
Sbjct 1259 MVLGA----------------GEAFTNNGMLTAGKGNSVFSAQRLFLNAPGSLQAGGDVS 1302
Query 1006 IQFFNEVYDGFVKKYSDIIEPNIYSQQLNGTKYSTQISIAVPFGDGDYARKEDILSPNGY 1065
+ +++ + + N+ LN ++ + F D + + DIL+ N
Sbjct 1303 LNSRSDITISGFTGTAGSLTMNVAGTLLNSALIYAGNNLKL-FTDRLHNQHGDILAGNSL 1361
Query 1066 FKYKYDQNKIRSEINYLSQLNGYEHFSSKLVSNSGSIDITSSKGISISGSELISKKGLVN 1125
+ K +EI ++ SG+I+ + +G L ++G
Sbjct 1362 WVQKDASGGANTEI----------------INTSGNIETHQGDIVVRTGHLLNQREGF-- 1403
Query 1126 IEALGALSQNYTSTIHGKDNKPKTLGASIIIDGSQDFYDKGNEN 1169
+ ++ S+I G N + S++ DGS ++ + EN
Sbjct 1404 --SATTTTRTNPSSIQGMGNALVDIPLSLLPDGSYGYFTREVEN 1445
Score = 60.5 bits (145), Expect = 3e-11
Identities = 140/689 (20%), Positives = 264/689 (38%), Gaps = 102/689 (15%)
Query 175 AGQRADVI---IANPAGINIKGGGFINANKAILTTGKPQLNADGSIQQFVVDQGKITISA 231
AG+ D+ +++ + + G IN +++ K Q + D + +
Sbjct 1997 AGKNIDITGATVSSGGTLGMSAGNDINIAANLISGSKSQSGF------WHTDDNSASSTT 2050
Query 232 NSGSSLGLGGNKNNADYVDLYARALELNAQLYANKDIQAITGANNISADLQQISTRTGTG 291
+ GSS+ GGN A +L A ++A A ++ N++S + + S + G
Sbjct 2051 SQGSSISAGGNLAMAAGHNLDVTASSVSAGHSA-----LLSAGNDLSLNAVRESKNSRNG 2105
Query 292 TTPTLAIDVKNLGGMYANNIYLLGNEKGLGVSNAGTIRAVNNLVVTSAGKI----EHKGS 347
+ + +N+ L+ S A + A NN+V+ + E G+
Sbjct 2106 RSESHESHAAVSTVTAGDNLLLVAGRDV--ASQAAGVAAENNVVIRGGRDVNLVAESAGA 2163
Query 348 LES-TSNTQGLVSIQTTQTGDNGNINSSGSITSKSMLSIDA-ANHLNITGNQVIVNQGVV 405
+S TS + ++ Q G I S G T + I A A+ + TGN + VN G
Sbjct 2164 GDSYTSKKKKEINETVRQQGTE--IASGGDTTVNAGRDITAVASSVTATGN-ISVNAGRD 2220
Query 406 SPLLLSAQGDINVSNGAIIKNVQTGGDIYLDAQNINVGENTQIANVGLVNLNAAAAIDIK 465
L + + D + YL+ + + G ++ + +A+ +
Sbjct 2221 VALTTATESDYH----------------YLETKKKSGGFLSKKTTHTISEDSAS-----R 2259
Query 466 KSARVKAVNDLNIIAKQGLSVADANLVAEKGNMNLQSNSNITLQGTTLDL------TKDL 519
++ + + N + + A L+V +++VA++ N L T+ D TK
Sbjct 2260 EAGSLLSGNRVTVNAGDNLTVEGSDVVADQDVSLAAGNHVDVLAATSTDTSWRFKETKKS 2319
Query 520 NINGTGNVNLSSLNFSLLNGSSTLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANLID 579
+ GTG + + GSS + +G Q+A + +GNV++ A
Sbjct 2320 GLMGTGGIGFTI-------GSSKTTHDRREAGTTQ--SQSASTIGSTAGNVSITAGKQAH 2370
Query 580 LKGSNLSGKGDLKLQGKALNV--GAD----------LTAGKSLNLTATQSDLILNKTLNA 627
+ GS++ D+ + G ++ V G D +G ++ L+ T I N +A
Sbjct 2371 ISGSDVIANRDISITGDSVVVDPGHDRRTVDEKFEQKKSGLTVALSGTVGSAINNAVTSA 2430
Query 628 QGNIDIASLDGKLNA--------TGLNATSSQGKLSIFGAKDTVLTNSGTVKTTLKGNQG 679
Q + S D +L A +G+ A + + G + + K Q
Sbjct 2431 QETKE--SSDSRLKALQATKTALSGVQAGQAAAMATATGDPNATGVSLSLTTQKSKSQQH 2488
Query 680 VNVGTISTGNLTLQNTVLESQNGAIVVTSEGQNTLTDSIITAKGNIELFAKDNLTLDGIK 739
T+S L N + G + G + S + A GN L A +++ L G
Sbjct 2489 SESDTVSGSTLNAGNNLSVVATGKNRGDNRGDIVIAGSQLKAGGNTSLDAANDVLLSG-A 2547
Query 740 SSSQQHTALNSKKNIYINSQAGTGD---------SVNF-------SSTKITE--LNSTGT 781
+++Q+ T NS + G G SVN + T+ TE ++S T
Sbjct 2548 ANTQKTTGRNSSSGGGVGVSIGAGGNGAGISVFASVNAAKGSEKGNGTEWTETTIDSGKT 2607
Query 782 LSLISDKNQNLQNTRLTGGAILLEAGGTL 810
+++ S ++ L ++ G I+ + G L
Sbjct 2608 VTINSGRDTVLNGAQVNGNRIIADVGHDL 2636
Score = 54.7 bits (130), Expect = 2e-09
Identities = 70/286 (24%), Positives = 121/286 (42%), Gaps = 26/286 (9%)
Query 1645 LAG--LAGAMQGELASQIGTHLDKVDPNVFEYAIHKIAHAAVGCAVAAATKSSCEAGAIG 1702
LAG LAGA+ G A ++ L + + A++ IAHA +G VAA ++ AGA G
Sbjct 2914 LAGGNLAGALAGASAPELAHLLKSTEKDP---AVNAIAHAILGGTVAAMQGNNVAAGAAG 2970
Query 1703 AGVGEI----VASLMPDPVNGIEYNEDEKTKIRNTGKIVAGVVSAYAGYDVNTA---ANS 1755
A GE+ +A ++ V + +E++K I + AG+ G +A A S
Sbjct 2971 AATGELAARAIAGMLYPGVKQSDLSEEQKQTISTLATVSAGLAGGLTGNSTASAAVGAQS 3030
Query 1756 ADIAIQNNSLVKLATSTGKILVKTLDEFNALRKAGKQVTKDDLVTSFKKQGADELIGIAD 1815
A++NN L + +I +TL + K K D + E+I
Sbjct 3031 GKNAVENNYLSVSEKTELEIAKQTLKNSKDPAEREKAQQKYDALLEKDIASDKEVIAACS 3090
Query 1816 DLLTVFGRSSSSFDRALAAIDLIVGTDLKPGKGESLKIAKNELEKLKTDRSYVQTVYQNK 1875
+ G +SSS A A + +I + + K ++ + +Y Q V N
Sbjct 3091 N-----GNASSS-ACASARLKVIASKEGYEDGPYNSKYSQQYAD------AYGQIV--NL 3136
Query 1876 IDVITRNRLNGKEFETSAASKLGIQRNTDRQMITVKTERDGQINII 1921
+D+ + + N ++ + + + + + DRQ TE + II
Sbjct 3137 LDITSVDAQNQQQVKNAMINYFMVTKGVDRQTAESYTETTQGLEII 3182
Score = 53.1 bits (126), Expect = 5e-09
Identities = 113/499 (23%), Positives = 197/499 (39%), Gaps = 58/499 (12%)
Query 227 ITISANSGSSLGLGGNKNNADYVDLYARALELNAQLYANKDIQAITGANNISADLQQIST 286
+T++ N + G +A + L A +++ + QL N IT + Q T
Sbjct 985 LTLTVNQTLNNHASGKLLSAGVLTLKADSVKNDGQLQGNAT--TITAGQLTNGGHLQGET 1042
Query 287 RTGTGTTPTLAIDVKNLGGMYANNIYLLGNEKGLGVSNAGTIRAVNNLVVTSAGKIEHKG 346
T T + ++ ++ G + + N N +SN GTI+ + + + ++++ G
Sbjct 1043 LTLTASG---GVNNRSGGVLMSRNAL---NVSTATLSNQGTIQGGGGVSLNATDRLQNDG 1096
Query 347 SLESTSNT-----------QGLVSIQT-----TQTGDNGNINSSGSITSKSMLSIDAANH 390
+ S SN GLV T T + G + ++GS K N
Sbjct 1097 KILSGSNLTLTAQVLANTGSGLVQAATLLLDVVNTVNGGRVLATGSADVK---GTTLNNT 1153
Query 391 LNITGNQVIVNQGVV--SPLLLSAQGDINVSNGAIIKN----VQTGGDIYLDAQNINVGE 444
+ G ++VN S LL G + V ++++N + + G++ LDAQ+ + G+
Sbjct 1154 GTLQGADLLVNYHTFSNSGTLLGTSG-LGVKGSSLLQNGTGRLYSAGNLLLDAQDFS-GQ 1211
Query 445 NTQIANVGLVNLNAAAAIDIKKSARVKAVNDLNIIAKQGLSVADANLVAEKGNMNLQSNS 504
Q+ G V L AA+ N + A + LSV N + G M Q ++
Sbjct 1212 G-QVVATGDVTLKLIAAL----------TNHGTLAAGKTLSVTSQNAITNGGVM--QGDA 1258
Query 505 NITLQGTTLDLTKDLNINGTGNVNLSSLNFSLLNGSSTLQNINAYSGLNLVWDQTAKALP 564
+ G + G GN ++ S LN +LQ S LN D T
Sbjct 1259 MVLGAGEAF-TNNGMLTAGKGN-SVFSAQRLFLNAPGSLQAGGDVS-LNSRSDITISGFT 1315
Query 565 QISGNVTLEAANLIDLKGSNLSGKGDLKLQGKAL-NVGADLTAGKSLNLTATQSDLILNK 623
+G++T+ A + L + + +LKL L N D+ AG SL + S +
Sbjct 1316 GTAGSLTMNVAGTL-LNSALIYAGNNLKLFTDRLHNQHGDILAGNSLWVQKDASGGANTE 1374
Query 624 TLNAQGNIDIASLDGKLNATGLNATSSQGKLSIFGAKDTVLTNSGTVKTTLKGNQGVNVG 683
+N GNI+ D + TG +G F A T TN +++ + +
Sbjct 1375 IINTSGNIETHQGDIVVR-TGHLLNQREG----FSATTTTRTNPSSIQGMGNALVDIPLS 1429
Query 684 TISTGNLTLQNTVLESQNG 702
+ G+ +E+Q+G
Sbjct 1430 LLPDGSYGYFTREVENQHG 1448
Score = 51.2 bits (121), Expect = 2e-08
Identities = 57/234 (24%), Positives = 103/234 (44%), Gaps = 20/234 (9%)
Query 1195 TGNSNQDNLVLQATGITAANGDVRIEANKNILFDAAIEQSYDRSTTTEKKSSWGGLKKKY 1254
T N+ +D + A+ +TA G++ + A +++ A E Y T KK S G L KK
Sbjct 2193 TVNAGRD-ITAVASSVTAT-GNISVNAGRDVALTTATESDYHYLET--KKKSGGFLSKKT 2248
Query 1255 ITTVSENNQANAASVDISGKNIFIESKEKNPANNIDIYSGKFIANGGQVSILSGGNINLY 1314
T+SE++ + A +SG + + N +N+ + +A+ VS+ +G ++++
Sbjct 2249 THTISEDSASREAGSLLSGNRVTV-----NAGDNLTVEGSDVVAD-QDVSLAAGNHVDVL 2302
Query 1315 TVQESSSS-NEDITKKSSFS-----GIKYNTSKTNATRNQISELPGILKADYIGIKADND 1368
+ +S TKKS G +SKT R + A IG A N
Sbjct 2303 AATSTDTSWRFKETKKSGLMGTGGIGFTIGSSKTTHDRREAGTTQS-QSASTIGSTAGN- 2360
Query 1369 VRLVGTEFEYLQAAKIQAGRNLSLLTASTTVTETLKKDKNSVVWQSMQDKGSVT 1422
V + + ++ + + A R++S+ S V D+ +V + Q K +T
Sbjct 2361 VSITAGKQAHISGSDVIANRDISITGDSVVVDP--GHDRRTVDEKFEQKKSGLT 2412
Score = 37.7 bits (86), Expect = 3e-04
Identities = 134/626 (21%), Positives = 217/626 (35%), Gaps = 130/626 (21%)
Query 1102 IDITSSK-GISISGSELISKKGLVNIEALGALSQNYTSTIHGKDNKPKTLGASIIIDGSQ 1160
I +TS++ G+ ++ L ++ G + ++A G L+ N + K G + + G
Sbjct 256 IHLTSTESGVGVNLGNLYARDGDITLDASGRLTVNNSLATGAVTAK----GQGVTLTGD- 310
Query 1161 DFYDKGNENDQKYRFRTILKPTLINGDKGVTIRATGNSNQDNLVLQATGITAANGDVRIE 1220
+ G R +L +N DK +++ A G Q N L A DV +
Sbjct 311 --HKAGGNLSVSSRSDIVLSNGTLNSDKDLSLTAGGRITQQNEKL------TAGRDVTLA 362
Query 1221 ANKNILFDAA---------IEQSYDRSTTTEKKSSWGGLKKKYIT--------------- 1256
A KNI D A + S D TT + ++ L T
Sbjct 363 A-KNITQDTASQINAARDIVTVSSDTLTTQGQITAGQNLTASATTLTQDGTLLAKGHAGL 421
Query 1257 ---TVSENNQANAASVDISGKNI------------------FIESKEKNPANNIDI-YSG 1294
T++ + AS+ + + F +S +DI SG
Sbjct 422 DAGTLNNSGAVQGASLTLGSTTLSNSGSLLSGGPLTVNTRDFTQSGRTGAKGKVDITASG 481
Query 1295 KFIANGGQVS---------------ILSGGNINLYTVQESSSSNEDITKKSSFSGIKYNT 1339
K + G VS +LSGG + Q SS + +T + + T
Sbjct 482 KLTSTGSLVSDDVLVLKAQDVTQNGVLSGGKGLTVSAQALSSGKKSVTHSDAAMTLNVTT 541
Query 1340 -------SKTNATRNQISELPGILKADY-----IGIKADNDVRLVGTE----------FE 1377
S + R Q +L A + I A D RL GT+ E
Sbjct 542 VALDGENSAGDTLRVQADKLSTAAGAQLQSGKNLSINA-RDARLAGTQAAQQTMAVNASE 600
Query 1378 YLQAAKIQAGRNLSL----LTASTTVTETLKKDKNSVVWQSMQDKGSVTETAQLPRFNGP 1433
L + + +LSL LT+S + + ++ + S +G + T R +
Sbjct 601 KLTHSGKSSAPSLSLSAPELTSSGVLVGSALNTQSQTLTNSGLLQGEASLTVNTQRLDNQ 660
Query 1434 TPPEFKAAGGLIVQIPIGEKDQNKIEIRDQILILANQPGNEYLKQLVNRNDV--DWQKVI 1491
+A L + IP +IR+ LI + L N + D V
Sbjct 661 QNGTLYSAADLTLDIP---------DIRNSGLITGDNGLTLNTASLSNPGKIIADTLNVR 711
Query 1492 LAQKDWDYKSQGLTGAGAAIIAIIVV-------MVTAGAGSAVVGALGGSATTLGGSAVV 1544
D D L GAGA +A + +TAG S L + TT G + V
Sbjct 712 ATTLDGDGL---LQGAGALALAGDTLSQGRNGRWLTAGDLSLRGKTLHTAGTTQGQNLTV 768
Query 1545 MTQAAVTSLATQASVSLINNG-GDLGKTLKDLGSKDSVKNLA-----ASVVTAGLLSQVG 1598
S + A+ +L + G L T + D+ N A S+++AG LS G
Sbjct 769 QADNWANSGSVLATGNLTASATGQLTSTGDIMSQGDTTLNAATTDNRGSLLSAGTLSLDG 828
Query 1599 SALNLKPDTSGFSARLLNNFTTAVGS 1624
++L+ + G + N T G+
Sbjct 829 NSLDNRGTVQGNHVTIRQNSVTNSGT 854
Score = 37.7 bits (86), Expect = 3e-04
Identities = 52/269 (19%), Positives = 103/269 (38%), Gaps = 48/269 (18%)
Query 1188 KGVTIRATGN---SNQDNLVLQATGITAANGDVRIEANKNILFDAAIEQSYDRSTTTEKK 1244
+G +I A GN + NL + A+ ++A + + + A ++ +A E R+ +E
Sbjct 2052 QGSSISAGGNLAMAAGHNLDVTASSVSAGHSAL-LSAGNDLSLNAVRESKNSRNGRSESH 2110
Query 1245 SSWGGLK-----------------KKYITTVSENNQANAASVDIS------GKNIFIESK 1281
S + + +ENN D++ G SK
Sbjct 2111 ESHAAVSTVTAGDNLLLVAGRDVASQAAGVAAENNVVIRGGRDVNLVAESAGAGDSYTSK 2170
Query 1282 EKNPANNIDIYSGKFIANGGQVSILSGGNINLYTVQESSSSNEDI--------------- 1326
+K N G IA+GG ++ +G +I +++ N +
Sbjct 2171 KKKEINETVRQQGTEIASGGDTTVNAGRDITAVASSVTATGNISVNAGRDVALTTATESD 2230
Query 1327 -----TKKSSFSGIKYNTSKTNATRNQISELPGILKADYIGIKADNDVRLVGTEFEYLQA 1381
TKK S + T+ T + + E +L + + + A +++ + G++ Q
Sbjct 2231 YHYLETKKKSGGFLSKKTTHTISEDSASREAGSLLSGNRVTVNAGDNLTVEGSDVVADQD 2290
Query 1382 AKIQAGRNLSLLTASTTVTE-TLKKDKNS 1409
+ AG ++ +L A++T T K+ K S
Sbjct 2291 VSLAAGNHVDVLAATSTDTSWRFKETKKS 2319
Score = 37.4 bits (85), Expect = 3e-04
Identities = 121/598 (20%), Positives = 225/598 (38%), Gaps = 89/598 (15%)
Query 1184 INGDKGVTIRATGNSNQDNLVLQATGITAANGDVRIEANKNILFDAAIEQSYDRSTTTEK 1243
IN G+++ +TG + N G+ +A G + + A + D + S T +
Sbjct 1897 INAQNGLSLDSTGYIDNLN-----AGLISAGGSLDLSA----IGDISNISSVISGKTVQL 1947
Query 1244 KSSWGGLKKKYITTVSENNQANAAS------VDISGKNIF-------IESKEKNPANNID 1290
+S G I+ ++ Q NA S V +SG + +S + NID
Sbjct 1948 ESVSGN-----ISNITRRQQWNAGSDSRYGGVHLSGTDTGPVATIKGTDSLSLDAGKNID 2002
Query 1291 IYSGKFIANGGQVSILSGGNINLYTVQESSSSNEDITKKSSFSGIKYNTSKTNATRNQIS 1350
I +G +++GG + + +G +IN+ S S ++ SG + + N+ + S
Sbjct 2003 I-TGATVSSGGTLGMSAGNDINIAANLISGSKSQ--------SGFWH--TDDNSASSTTS 2051
Query 1351 ELPGILKADYIGIKADNDVRLVGTEFEYLQAAKIQAGRNLSLLTASTTVTETLKKDKNSV 1410
+ I + + A +++ + + +A + AG +LSL +++ KNS
Sbjct 2052 QGSSISAGGNLAMAAGHNLDVTASSVSAGHSALLSAGNDLSL--------NAVRESKNSR 2103
Query 1411 VWQSMQDKGSVTETAQLPRFNGPTPPEFKAAGGLIVQIPIGEKDQNKIEIRD--QILILA 1468
+S + + N AG + G +N + IR + ++A
Sbjct 2104 NGRSESHESHAAVSTVTAGDN-----LLLVAGRDVASQAAGVAAENNVVIRGGRDVNLVA 2158
Query 1469 NQPGNEYLKQLVNRNDVDWQKVILAQKDWDYKSQGLTGAGAAIIAIIVVMVTAGAGSAVV 1528
G + +++ + Q+ + S G T T AG +
Sbjct 2159 ESAGAGDSYTSKKKKEIN---ETVRQQGTEIASGGDT--------------TVNAGRDIT 2201
Query 1529 GALGGSATTLGGSAVVMTQAAVTSLATQASVSLI----NNGGDLGKTLKDLGSKDSVKNL 1584
A+ S T G +V + + AT++ + +GG L K S+DS
Sbjct 2202 -AVASSVTATGNISVNAGRDVALTTATESDYHYLETKKKSGGFLSKKTTHTISEDSASRE 2260
Query 1585 AASVVTAGLLSQVGSALNLKPDTSGFSARLLNNFTTAVGSTLVQTAIKGGDLEDNLKVAL 1644
A S+++ ++ V + NL + S A + + A G+ + A D K
Sbjct 2261 AGSLLSGNRVT-VNAGDNLTVEGSDVVAD--QDVSLAAGNHVDVLAATSTDTSWRFKETK 2317
Query 1645 LAGLAGAMQGELASQIG----THLDKVDPNVFEYAIHKIAHAAVGCAVAAATKSSCEAGA 1700
+GL G G + IG TH + + I A ++ A ++
Sbjct 2318 KSGLMGT--GGIGFTIGSSKTTHDRREAGTTQSQSASTIGSTAGNVSITAGKQAHISGSD 2375
Query 1701 IGAG--VGEIVASLMPDPVNGIEYNEDEKTKIRNTGKIVAGVVSAYAGYDVNTAANSA 1756
+ A + S++ DP + DEK + + +G VA +S G +N A SA
Sbjct 2376 VIANRDISITGDSVVVDPGHD-RRTVDEKFEQKKSGLTVA--LSGTVGSAINNAVTSA 2430
Score = 32.7 bits (73), Expect = 0.008
Identities = 72/313 (23%), Positives = 109/313 (35%), Gaps = 31/313 (10%)
Query 77 NSANAGNR-PVIGVGQNSQGQN---VPVVNIQTPTNGVSHNIYKQMDVLPEGVVLNNSRT 132
++ NAGN V+ G+N +G N + + Q G + ++ DVL G T
Sbjct 2497 STLNAGNNLSVVATGKN-RGDNRGDIVIAGSQLKAGG-NTSLDAANDVLLSGAANTQKTT 2554
Query 133 GANSSLVGTVGANPFLAKGEARI-ILNEVNSSVASRFEGN----LEVAGQRADVIIANPA 187
G NSS G VG + A I + VN++ S +GN E + N
Sbjct 2555 GRNSSSGGGVGVSIGAGGNGAGISVFASVNAAKGSE-KGNGTEWTETTIDSGKTVTINSG 2613
Query 188 GINIKGGGFINANKAILTTGKPQLNAD-------GSIQQFVVDQGKITISANSGSSLGLG 240
+ G +N N+ I G L + S Q V G T + +GS
Sbjct 2614 RDTVLNGAQVNGNRIIADVGHDLLISSQQDTSKYDSKQTSVAAGGSFTFGSMTGSGYIAA 2673
Query 241 GNKNNADYVDLYARALELNAQLYANKDIQAITGANNISADLQQISTRTGTGTTPTLAIDV 300
D A +++ IT N+ D I++ T T ++D
Sbjct 2674 SRDKMKSRFDSVAE----QTGMFSGDGGFDITVGNHTQLDGAVIAS---TATADKNSLDT 2726
Query 301 KNLG-GMYANNIYLLGNEKGLGVSNAGTI--RAVNNLVVTSAGKIEHKGSLESTSNTQGL 357
LG N + G+ +S G+ + N+ H G E T TQ
Sbjct 2727 GTLGFSDIHNEADYKVSHSGISLSGGGSFGDKFQGNMPGGMISAGGHSGHAEGT--TQAA 2784
Query 358 VSIQTTQTGDNGN 370
V+ T D N
Sbjct 2785 VADGTITIRDRDN 2797
Score = 30.8 bits (68), Expect = 0.032
Identities = 111/564 (20%), Positives = 201/564 (36%), Gaps = 66/564 (12%)
Query 1128 ALGALSQNYTSTIHGKDNKPKTLGASIIIDGSQDFYDKGNENDQKYRFRTILKPTLINGD 1187
AL + + + P G S+ + + + +E+D T+ TL N
Sbjct 2450 ALSGVQAGQAAAMATATGDPNATGVSLSLTTQKSKSQQHSESD------TVSGSTL-NAG 2502
Query 1188 KGVTIRATGNSNQDNL--VLQATGITAANGDVRIEANKNILFDAAIEQSYDRSTTTEKKS 1245
+++ ATG + DN ++ A A G+ ++A ++L A + TT S
Sbjct 2503 NNLSVVATGKNRGDNRGDIVIAGSQLKAGGNTSLDAANDVLLSGAANT---QKTTGRNSS 2559
Query 1246 SWGGLKKKY--------ITTVSENNQANAA-----------SVDISGKNIFIESKEKNPA 1286
S GG+ I+ + N A + ++D SGK + I S
Sbjct 2560 SGGGVGVSIGAGGNGAGISVFASVNAAKGSEKGNGTEWTETTID-SGKTVTINSGRDTVL 2618
Query 1287 NNIDIYSGKFIAN-GGQVSILSGGNINLYTVQESSSSNEDITKKSSFSGIKY---NTSKT 1342
N + + IA+ G + I S + + Y +++S + S +G Y + K
Sbjct 2619 NGAQVNGNRIIADVGHDLLISSQQDTSKYDSKQTSVAAGGSFTFGSMTGSGYIAASRDKM 2678
Query 1343 NATRNQISELPGILKADY-IGIKADNDVRLVGTEFEYLQAAKIQAGRNLSLLTASTTVTE 1401
+ + ++E G+ D I N +L G A + + L S E
Sbjct 2679 KSRFDSVAEQTGMFSGDGGFDITVGNHTQLDGAVIASTATAD-KNSLDTGTLGFSDIHNE 2737
Query 1402 TLKKDKNSVVWQSMQDKGSVTETAQLPRFNGPTPPEFKAAGGLIVQIPIGEKDQNKIEIR 1461
K +S + S+ GS + +F G P +AGG + + +
Sbjct 2738 ADYKVSHSGI--SLSGGGSFGD-----KFQGNMPGGMISAGGHSGHA----EGTTQAAVA 2786
Query 1462 DQILILANQPGNEYLKQLVNRNDVDWQKVILAQKDWDYKSQGLTGAGAAIIAIIVVMVTA 1521
D + + ++ + ++R+ I D + + + L G ++
Sbjct 2787 DGTITIRDRDNQKQNLANLSRDPAHANDSISPIFDKEKEQRRLQTVG--------LISDI 2838
Query 1522 GAGSAVVGALGGSATTLGGSAVVM--TQAAVTSLATQASVSLINNGGDLGKTLKDLGSKD 1579
G+ A + G L + A T QA ++ + + + K + G+
Sbjct 2839 GSQVADIARTQGELNALKAAQDKYGPVPADATEEQRQAYLAKLRDTPEYKKEQEKYGTGS 2898
Query 1580 SVKNLAASVVTAGLLSQVGSALNLKPDTSGFSA----RLLNNFTTAVGSTLVQTAIKGGD 1635
++ TA L G NL +G SA LL + + AI GG
Sbjct 2899 EIQR-GIQAATAALQGLAGG--NLAGALAGASAPELAHLLKSTEKDPAVNAIAHAILGGT 2955
Query 1636 LEDNLKVALLAGLAGAMQGELASQ 1659
+ + AG AGA GELA++
Sbjct 2956 VAAMQGNNVAAGAAGAATGELAAR 2979
Score = 29.3 bits (64), Expect = 0.093
Identities = 62/280 (22%), Positives = 107/280 (38%), Gaps = 35/280 (13%)
Query 1092 SSKLVSNSGSIDITSSKGISISGSELISKKGLVNIEALGALSQNYTSTIHGKDNKPKTLG 1151
+S+ +++SG +S+ +S+S EL S LV AL SQ T N G
Sbjct 598 ASEKLTHSGK---SSAPSLSLSAPELTSSGVLVG-SALNTQSQTLT-------NSGLLQG 646
Query 1152 ASIIIDGSQDFYDKGNEN-----DQKYRFRTILKPTLINGDKGVTIRATGNSNQDNLVLQ 1206
+ + +Q ++ N D I LI GD G+T+ SN ++
Sbjct 647 EASLTVNTQRLDNQQNGTLYSAADLTLDIPDIRNSGLITGDNGLTLNTASLSNPGKIIAD 706
Query 1207 ATGI--TAANGDVRIE-ANKNILFDAAIEQSYDRSTTTE-------KKSSWGGLKKKYIT 1256
+ T +GD ++ A L + Q + T K G +
Sbjct 707 TLNVRATTLDGDGLLQGAGALALAGDTLSQGRNGRWLTAGDLSLRGKTLHTAGTTQGQNL 766
Query 1257 TVSENNQANAASVDISGKNIFIESKEKNPANNIDIYSGKFIANGGQV----SILSGGNIN 1312
TV +N AN+ SV +G N+ + + + + G N S+LS G ++
Sbjct 767 TVQADNWANSGSVLATG-NLTASATGQLTSTGDIMSQGDTTLNAATTDNRGSLLSAGTLS 825
Query 1313 LYTVQESSSSNEDITKKSSFSGIKYNTSKTNATRNQISEL 1352
L + +S + T + + I+ N+ + T I+ L
Sbjct 826 L----DGNSLDNRGTVQGNHVTIRQNSVTNSGTLTGIAAL 861
Score = 28.9 bits (63), Expect = 0.12
Identities = 67/295 (23%), Positives = 120/295 (41%), Gaps = 45/295 (15%)
Query 1557 ASVSLINNGGDLG-KTLKDLGSKDSVKNLAASVVTAGL---LSQVGSALNLKPDTSGFSA 1612
A ++ N+GG + + L S + NL A +++AG LS +G N+ SG +
Sbjct 1886 AGGNITNSGGSINAQNGLSLDSTGYIDNLNAGLISAGGSLDLSAIGDISNISSVISGKTV 1945
Query 1613 RLLNNFTTAVGSTLVQTAIKGGDLEDNLKVALLAGLAGAMQGELASQIGTHLDKVDPNVF 1672
+L + T Q G D L+G G +A+ GT +D
Sbjct 1946 QLESVSGNISNITRRQQWNAGSDSRYGG-----VHLSGTDTGPVATIKGTDSLSLD---- 1996
Query 1673 EYAIHKIAHAAVGCAVAAATKSSCEAGAIGAGVGE---IVASLMPDPVN--GIEYNEDEK 1727
A + AT SS G +G G I A+L+ + G + +D
Sbjct 1997 ---------AGKNIDITGATVSS--GGTLGMSAGNDINIAANLISGSKSQSGFWHTDDNS 2045
Query 1728 ---TKIRNTGKIVAGVVSAYAGYDVNTAANSADIAIQNNSLVKLATSTGKILVKTLDEFN 1784
T + + G ++ AG++++ A+S ++ +++L+ S G L N
Sbjct 2046 ASSTTSQGSSISAGGNLAMAAGHNLDVTASS--VSAGHSALL----SAGNDL-----SLN 2094
Query 1785 ALRKAGKQVTKDDLVTSFKKQGADELIGIADDLLTVFGRSSSSFDRALAAIDLIV 1839
A+R++ +++ S + A + D+LL V GR +S +AA + +V
Sbjct 2095 AVRESKN--SRNGRSESHESHAAVSTVTAGDNLLLVAGRDVASQAAGVAAENNVV 2147
Score = 25.8 bits (55), Expect = 1.0
Identities = 54/270 (20%), Positives = 97/270 (36%), Gaps = 38/270 (14%)
Query 1158 GSQDFYDK-GNENDQKYRFRTILKPTLINGDKGVTIRATGNSNQDNLVLQATGITAANGD 1216
GS F D+ G + ++ YRF GD R N+ VL TG NG
Sbjct 1759 GSSYFLDRLGLKPEKDYRFL---------GDAVFDTRYVSNA-----VLSRTGSRYLNGL 1804
Query 1217 VRIEANKNILFDAAIEQS------YDRSTTTEKKSSWGGLKKKYITTVSENNQANAASVD 1270
L D A Q + + T E+ + G + + +
Sbjct 1805 GSDTEQMRYLMDNAARQQKGLGLEFGVALTAEQIAQLDGSILWWESATINGQTVMVPKLY 1864
Query 1271 ISGKNIFIESKEKNPANNIDIYSGKFIANGGQVSILSGGNI-------NLYTVQESSSSN 1323
+S ++I + + NN+ + G +GG ++ +G ++ NL S+ +
Sbjct 1865 LSPEDITLHNGSVISGNNVQLAGGNITNSGGSINAQNGLSLDSTGYIDNLNAGLISAGGS 1924
Query 1324 EDITKKSSFSGIKYNTS-KTNATRNQISELPGILKADYIGIKADN---DVRLVGTE---- 1375
D++ S I S KT + + I + +D+ V L GT+
Sbjct 1925 LDLSAIGDISNISSVISGKTVQLESVSGNISNITRRQQWNAGSDSRYGGVHLSGTDTGPV 1984
Query 1376 --FEYLQAAKIQAGRNLSLLTASTTVTETL 1403
+ + + AG+N+ + A+ + TL
Sbjct 1985 ATIKGTDSLSLDAGKNIDITGATVSSGGTL 2014
>P12255 Filamentous hemagglutinin [Bordetella pertussis (strain
Tohama I / ATCC BAA-589 / NCTC 13251)]
Length=3590
Score = 197 bits (500), Expect = 1e-52
Identities = 235/976 (24%), Positives = 415/976 (43%), Gaps = 155/976 (16%)
Query 1 MNKNRYRVVYNQARQMFMAVAEN----------VKSQTKTSGQSTASSVTVEQSQPFHQL 50
MN N YR+V++ R M + V+E+ + Q ++ ++T+ SV P
Sbjct 1 MNTNLYRLVFSHVRGMLVPVSEHCTVGNTFCGRTRGQARSGARATSLSVA-----PNALA 55
Query 51 WQVKCLVASMSLWMPLAPVYAQIQADNSANAGNRPVIGVGQNSQGQNVPVVNIQTPTNG- 109
W + + L A G V+ G VPVVNI P +G
Sbjct 56 WALMLACTGLPL---------VTHAQGLVPQGQTQVL-----QGGNKVPVVNIADPNSGG 101
Query 110 VSHNIYKQMDVLPEGVVLNNSRTGANSSLVGTVGANPFLAKGEARIILNEVNSSVASRFE 169
VSHN ++Q +V GVV NN T S + G + NP L + +A IL EV + SR
Sbjct 102 VSHNKFQQFNVANPGVVFNNGLTDGVSRIGGALTKNPNLTR-QASAILAEVTDTSPSRLA 160
Query 170 GNLEVAGQRADVIIANPAGINIKGGGFINANKAILTTGKPQLNADGSIQQFVVDQGKITI 229
G LEV G+ AD+IIANP GI++ G +NA+ LTTG+P +N G V QG +TI
Sbjct 161 GTLEVYGKGADLIIANPNGISVNGLSTLNASNLTLTTGRPSVN--GGRIGLDVQQGTVTI 218
Query 230 SANSGSSLGLGGNKNNADYVDLYARALELNAQLYANK-----DIQAITGANNISADLQQ- 283
++ GLG Y D+ AR ++L + + + DI + GAN ++
Sbjct 219 ERGGVNATGLG-------YFDVVARLVKLQGAVSSKQGKPLADIAVVAGANRYDHATRRA 271
Query 284 --ISTRTGTGTTPTLAIDVKNLGGMYANNIYLLGNEKGLGVSNAGTIRAVNNLVVTSAGK 341
I+ AID G MY +I L+ ++ GLGV G++ + + + V+S G+
Sbjct 272 TPIAAGARGAAAGAYAIDGTAAGAMYGKHITLVSSDSGLGVRQLGSLSSPSAITVSSQGE 331
Query 342 IEHKGSLESTSNTQGLVSIQTTQTGDNGNINSSG---SITSKSMLSIDAANHLNITGNQV 398
I +L + +G +S++ G + S G ++ + I +A+ + GN
Sbjct 332 I----ALGDATVQRGPLSLKGAGVVSAGKLASGGGAVNVAGGGAVKIASASSV---GNLA 384
Query 399 IVNQGVVSPLLLSAQGDINVSNGAIIK----------NVQTGGDIYLD----AQNINVGE 444
+ G V LL+A G + VS ++ +V GG + D + ++V +
Sbjct 385 VQGGGKVQATLLNAGGTLLVSGRQAVQLGAASSRQALSVNAGGALKADKLSATRRVDV-D 443
Query 445 NTQIANVGLVNLNAAA--AIDIKKSARVKAVNDLNIIAKQGLSVADANLVAEKGNMNLQS 502
Q +G + NA + A K+ ++ A L++ KQ +++ VA G +++ +
Sbjct 444 GKQAVALGSASSNALSVRAGGALKAGKLSATGRLDVDGKQAVTLGS---VASDGALSVSA 500
Query 503 NSNITLQGTTLDLTKDLNINGTGNVNLSSLNFSLLNGSSTLQNINAYSGLNLVWDQTAKA 562
N L+ L + L + G V L + + T+ A + NL +K
Sbjct 501 GGN--LRAKQLVSSAQLEVRGQREVALDDASSA---RGMTVVAAGALAARNL----QSKG 551
Query 563 LPQISGNVTLEAANLIDLKGSNLSGKGDLKLQGKALNVGADLTAGKSLNLTATQSDLILN 622
+ G + AN + G+G + L + GAD++ +N+ +SD +
Sbjct 552 AIGVQGGEAVSVANANSDAELRVRGRGQVDLHDLSAARGADISGEGRVNIGRARSD--SD 609
Query 623 KTLNAQGNIDIASLDGKLNATGLNATSSQGKLSIFGAKDTVLTNSGTVKTTLKGNQGVNV 682
++A G + I S+ L A G+ A S AKD + + G V T+ G VN+
Sbjct 610 VKVSAHGALSIDSMTA-LGAIGVQAGGS------VSAKD--MRSRGAV--TVSGGGAVNL 658
Query 683 GTI---------STGNLTLQNTVLESQNGAIVVTSEGQNTLTDSIITAKGNIELFAKDNL 733
G + S G +T+++ A + + + L + + G + + +D +
Sbjct 659 GDVQSDGQVRATSAGAMTVRDVA-----AAADLALQAGDALQAGFLKSAGAMTVNGRDAV 713
Query 734 TLDGIKSSSQQHTALNSKKNIYINSQAGTGDSVNFS--STKITELNSTGTLSLISDKNQN 791
LDG + Q ++S + S A G+ + + + EL S +S+ + +
Sbjct 714 RLDGAHAGGQ--LRVSSDGQAALGSLAAKGELTVSAARAATVAELKSLDNISVTGGERVS 771
Query 792 LQNTRLTGGAILLEAGGTLNTPKVIE--------FNATGSNLLKNDSKLNSLNGDLSIQT 843
+Q+ + + + A G L+ KV + A G++ L +D G +S+
Sbjct 772 VQSVN-SASRVAISAHGALDVGKVSAKSGIGLEGWGAVGADSLGSD-------GAISVSG 823
Query 844 KESLTIDPNIHTLKAIGDIELASKQGTLILAGYGGQAGNGSEKVLNLTTTGGGISLEGAS 903
++++ +D +++ DI L ++ G L G I + G S
Sbjct 824 RDAVRVD----QARSLADISLGAEGGA----------------TLGAVEAAGSIDVRGGS 863
Query 904 VELQGAQLNAEKNIKI 919
+ L+A +++++
Sbjct 864 T-VAANSLHANRDVRV 878
Score = 74.3 bits (181), Expect = 2e-15
Identities = 182/928 (20%), Positives = 340/928 (37%), Gaps = 168/928 (18%)
Query 170 GNLEVAGQRADVI--IANPAGINIKGGGFINANKAILTTGKPQLNADGSIQQFVVD---- 223
G L+V G++A + +A+ +++ GG + A + + + QL G + + D
Sbjct 475 GRLDVDGKQAVTLGSVASDGALSVSAGGNLRAKQLVSSA---QLEVRGQREVALDDASSA 531
Query 224 ----------------QGKITISANSGSSLGLGGNKNNADY-------VDLYARALELNA 260
Q K I G ++ + ++A+ VDL+ + A
Sbjct 532 RGMTVVAAGALAARNLQSKGAIGVQGGEAVSVANANSDAELRVRGRGQVDLHDLSAARGA 591
Query 261 QLYANKDIQAITGANNISADLQQISTRTGTGTTPTLAIDVKNLGGMYANNIYLLG--NEK 318
+ + ++ + + T AI V+ G + A ++ G
Sbjct 592 DISGEGRVNIGRARSDSDVKVSAHGALSIDSMTALGAIGVQAGGSVSAKDMRSRGAVTVS 651
Query 319 GLGVSNAGTIRAVNNLVVTSAGKIEHKGSLESTSNTQGLVSIQTTQTGDNGNINSSGSIT 378
G G N G +++ + TSAG + + + +++Q G + S+G++T
Sbjct 652 GGGAVNLGDVQSDGQVRATSAGAMTVRDVAAAAD-----LALQAGDALQAGFLKSAGAMT 706
Query 379 --SKSMLSIDAANHLNITGNQVIVNQGVVSPL-LLSAQGDINVSNGAI--------IKNV 427
+ + +D A+ G Q+ V+ + L L+A+G++ VS + N+
Sbjct 707 VNGRDAVRLDGAH----AGGQLRVSSDGQAALGSLAAKGELTVSAARAATVAELKSLDNI 762
Query 428 QTGGDIYLDAQNIN--------------VGENTQIANVGLVNLNAAAAIDIKKSARVKAV 473
G + Q++N VG+ + + +GL A A + +
Sbjct 763 SVTGGERVSVQSVNSASRVAISAHGALDVGKVSAKSGIGLEGWGAVGADSLGSDGAISVS 822
Query 474 NDLNIIAKQGLSVADANLVAEKGNM--------NLQSNSNITLQGTTLDLTKDLNINGTG 525
+ Q S+AD +L AE G ++ T+ +L +D+ ++G
Sbjct 823 GRDAVRVDQARSLADISLGAEGGATLGAVEAAGSIDVRGGSTVAANSLHANRDVRVSGKD 882
Query 526 NVNLS----------SLNFSLLNGSSTLQNINAYSGLNLVWDQTAKALP--QISGNVTLE 573
V ++ S L G+ + A G V Q+AKA + G L+
Sbjct 883 AVRVTAATSGGGLHVSSGRQLDLGAVQARGALALDGGAGVALQSAKASGTLHVQGGEHLD 942
Query 574 AANLIDLKGSNLSGKGDLKLQGKALNVGADLTAGKS--LNLTATQSDLILNKTLNAQGNI 631
L + +++G GD+++ + GADL AG+S L + T DL AQ +
Sbjct 943 LGTLAAVGAVDVNGTGDVRVAKLVSDAGADLQAGRSMTLGIVDTTGDL----QARAQQKL 998
Query 632 DIASL--DGKLNAT-----GLNATSSQGKLSIFGAKDTVLTNSGTVKTTLKGNQGVNVGT 684
++ S+ DG L A L A G L + G TV + + + V +G
Sbjct 999 ELGSVKSDGGLQAAAGGALSLAAAEVAGALELSGQGVTV-DRASASRARIDSTGSVGIGA 1057
Query 685 ISTGNLTLQNTVLESQ--------NGAIVVTSEGQNTL------------TDSIITAKGN 724
+ G + + + G++VV ++G T+ D I+ AKG
Sbjct 1058 LKAGAVEAASPRRARRALRQDFFTPGSVVVRAQGNVTVGRGDPHQGVLAQGDIIMDAKGG 1117
Query 725 IELFAKDNLTLDG-----IKSSSQQHTALNSKKNIYINSQAGTGDSVNFSSTKITELNST 779
L D LT +G S+ +H+ + SK + + + G S +L
Sbjct 1118 TLLLRNDALTENGTVTISADSAVLEHSTIESKISQSVLAAKGDKGKPAVSVKVAKKLFLN 1177
Query 780 GTLSLISDKNQNLQNTRL-----------------------TGGAILLEAGGTLNTPKVI 816
GTL ++D N+ + ++ A L+ GG P V+
Sbjct 1178 GTLRAVNDNNETMSGRQIDVVDGRPQITDAVTGEARKDESVVSDAALVADGG----PIVV 1233
Query 817 EFNATGSNLLKNDSKLNSLNG-DLSIQTKESLTIDPNIHTLKAIGDIELASKQGTLILAG 875
E S+ + N NG ++++T +L I K G +E+ L G
Sbjct 1234 EAGELVSHAGGIGNGRNKENGASVTVRTTGNLVNKGYISAGKQ-GVLEVGGALTNEFLVG 1292
Query 876 YGGQAGNGSEKVLNLTT--------TGGGISLEGASVELQGAQLNAEKNIKILANNENIQ 927
G ++++ N T T G + ++ A + + + ++I
Sbjct 1293 SDGTQRIEAQRIENRGTFQSQAPAGTAGALVVKAAEAIVHDGVMATKGEMQIAGKGGGSP 1352
Query 928 IISIKNKLNNSKLSDSNKLLVDLVEIDN 955
++ K S +NKL VD+ DN
Sbjct 1353 TVTAGAKATTS----ANKLSVDVASWDN 1376
Score = 63.9 bits (154), Expect = 3e-12
Identities = 142/659 (22%), Positives = 255/659 (39%), Gaps = 129/659 (20%)
Query 127 LNNSRTGANSSLVGTVGANPFLAKGEARIILNEVNSS-----VASRFEGNLEVAGQRADV 181
+ N T + + GT GA + K I+ + V ++ +A + G+ V
Sbjct 1304 IENRGTFQSQAPAGTAGA--LVVKAAEAIVHDGVMATKGEMQIAGKGGGSPTVTAGAKAT 1361
Query 182 IIANPAGINIKGGGFINANKAILTTGKPQLNADGSIQQF--VVDQGKITISANS----GS 235
AN +++ + NA + G Q+ G + V QG T+SA++
Sbjct 1362 TSANKLSVDV--ASWDNAGSLDIKKGGAQVTVAGRYAEHGEVSIQGDYTVSADAIALAAQ 1419
Query 236 SLGLGGNKNNADYVDL-YARALELNAQLYAN-------------KDIQAITGANNISADL 281
GG N D ++ + L L N ++ +T A+ +
Sbjct 1420 VTQRGGAANLTSRHDTRFSNKIRLMGPLQVNAGGAVSNTGNLKVREGVTVTAASFDNETG 1479
Query 282 QQISTRTGTGTTPTLAIDVKNLGGMYANNIYLLGNEKGLGVSNAGTIRAVNNLVVTSAGK 341
++ ++ T TT A +N G M + VSN GT A ++ VTS G
Sbjct 1480 AEVMAKSATLTTSGAA---RNAGKMQVKEAATI---VAASVSNPGTFTAGKDITVTSRGG 1533
Query 342 IEHKGSLESTSNTQGLVSIQTTQTGDNGNINSSGSITSKSMLSIDAANHLNITGNQVIVN 401
+++G +ES + + I+T Q NG + +DA + L +T + N
Sbjct 1534 FDNEGKMESNKD----IVIKTEQF-SNGRV-------------LDAKHDLTVTASGQADN 1575
Query 402 QGVVSPLLLSAQGDINVSNGAIIKN--VQTGGDIYLDAQNI-NVGENTQIANVGLVNLNA 458
+G L A D V I + + G D L A ++ N G+ ++ ++N
Sbjct 1576 RG-----SLKAGHDFTVQAQRIDNSGTMAAGHDATLKAPHLRNTGQVVAGHDIHIIN--- 1627
Query 459 AAAIDIKKSARVKAVNDLNIIAKQGLSVADANLVAEKGNMNLQSNSNITL-QGTTLDLTK 517
+ ++ + RV A ND+ L VAD G++ + ++ +TL QGT DL
Sbjct 1628 --SAKLENTGRVDARNDI------ALDVAD---FTNTGSLYAEHDATLTLAQGTQRDLVV 1676
Query 518 DLN-----INGTGNVNLSSLNFSLLNG------SSTLQNINAYSGLNLVWDQT------- 559
D + GT V SL + G + +NI+ + + D T
Sbjct 1677 DQDHILPVAEGTLRVKAKSLTTEIETGNPGSLIAEVQENIDNKQAIVVGKDLTLSSAHGN 1736
Query 560 ----AKALPQISGNVTLEAANLIDLKGSNLSGKGDLKLQGKA--LNVGADLTAGKSLNLT 613
A AL +G +T++A N+ + + + + G+ +L LN + AG+ ++L
Sbjct 1737 VANEANALLWAAGELTVKAQNITNKRAALIEAGGNARLTAAVALLNKLGRIRAGEDMHLD 1796
Query 614 ATQSDLILNKTLNAQGNIDIASLDGKLNATGLNATSSQGKLSIFGAKDTVLTNSGTVKTT 673
A + + + A L G++ G+ + G + + G V
Sbjct 1797 APRIE-------------NTAKLSGEVQRKGVQ--------DVGGGEHGRWSGIGYVNYW 1835
Query 674 LKGNQGVNVGTIST----GNLTLQNTVLESQN----GAIVVTSEGQNTLTDSIITAKGN 724
L+ G GTI+ G+LT + +++E A E ++ L + +I A G+
Sbjct 1836 LRAGNGKKAGTIAAPWYGGDLTAEQSLIEVGKDLYLNAGARKDEHRHLLNEGVIQAGGH 1894
Score = 31.2 bits (69), Expect = 0.024
Identities = 147/714 (21%), Positives = 244/714 (34%), Gaps = 108/714 (15%)
Query 188 GINIKGGGFINANKAILTTGKPQLNADGSIQ--QFVVDQGKITISANSGSSLGLGGNKNN 245
G I GG + N T G + +G IQ VD GK + S G GG
Sbjct 2500 GALIASGGDVTVN----TDGHDVSSVNGLIQGRSVKVDAGKGKVVV--ADSKGAGGGIEA 2553
Query 246 ADYVDLYARALELNAQLYANKDIQAITGANNISADLQQISTRTGTGTTPTLAIDVKNLGG 305
D VD+ R + + KD++ + AD +++T LA + G
Sbjct 2554 DDEVDVSGRDIGIEGGKLRGKDVR-------LKADTVKVATSMRYDDKGRLA--ARGDGA 2604
Query 306 MYANNIYLLGNEKGLGVSNAGTIRAVNNLVVTSA---GKIEHKGSLESTSNTQ--GLVSI 360
+ A L K L + A L V G E S E+ S+T L +I
Sbjct 2605 LDAQGGQLHIEAKRLETAGATLKGGKVKLDVDDVKLGGVYEAGSSYENKSSTPLGSLFAI 2664
Query 361 --QTTQTGDNGNINSSGSITSKSMLSIDAANHLNITGNQVIVNQGVVSPLLLSAQGDINV 418
TT+T + + N G+ L N L I G V +A D++V
Sbjct 2665 LSSTTETNQSAHANHYGTRIEAGTLEGKMQN-LEIEGGSVD-----------AAHTDLSV 2712
Query 419 SNGAIIKNVQ--TGGDIYLDAQNINVGENTQIANVGLVNLNAAAAIDIKKSARVKAVNDL 476
+ A K + D + +++G A VG A ++ + A +
Sbjct 2713 ARDARFKAAADFAHAEHEKDVRQLSLG-----AKVGAGGYEAGFSLGSESGLEAHAGRGM 2767
Query 477 NIIA--KQGLSVA-DANLVAEKG--NMNLQSNSNITLQGTTLDLT-KDLNIN-----GTG 525
A K G + + + EK N NL G LD+ D+N N G
Sbjct 2768 TAGAEVKVGYRASHEQSSETEKSYRNANLNFGGGSVEAGNVLDIGGADINRNRYGGAAKG 2827
Query 526 NVNLSSLNFSLLNGSSTLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANLIDLKGSNL 585
N + + ++ + + W + ++ A L D N+
Sbjct 2828 NAGTEEALRMRAKKVESTKYVSEQTSQSSGWSVEVASTASARSSLLTAATRLGDSVAQNV 2887
Query 586 SGKGDLKLQGKALNVGAD-------------LTAGKSLNLTATQSDLILNKTLNAQGNID 632
+++ + A V A+ L+AG S + ++ S T GN+
Sbjct 2888 EDGREIRGELMAAQVAAEATQLVTADTAAVALSAGISADFDSSHSRSTSQNTQYLGGNLS 2947
Query 633 IASLDGKLNATGLN-------ATSSQGKLSIFGAKDTV--LTNSGTVKTTLKGNQGVNV- 682
I + +G G + + +++ A+ T + S + N G N
Sbjct 2948 IEATEGDATLVGAKFGGGDQVSLKAAKSVNLMAAESTFESYSESHNFHASADANLGANAV 3007
Query 683 -GTISTGNLTLQNTVLESQNGAIVVTSEGQNTLTDSIITAKGNIELFAKDNLTLDGIKSS 741
G + G T + +T+E T + + A N+ + A +L L G +
Sbjct 3008 QGAVGLGLTAGMGTSHQ-------ITNETGKTYAGTSVDA-ANVSIDAGKDLNLSGSRVR 3059
Query 742 SQQHTALNSKKNI----------YINSQAGTGDSVNFSSTKITELNSTGTLSLISDKNQN 791
+H L+ + +I Y +S G S + T + G+ + N
Sbjct 3060 G-KHVVLDVEGDINATSKQDERNYNSSGGGWDASAGVAIQNRTLVAPVGSAGF--NFNTE 3116
Query 792 LQNTRLTG-GAILLEAGGTLNTPKVIEFNATGSNL--------LKNDSKLNSLN 836
N+RLT GA + A L + N TG+ + LK D +N+ N
Sbjct 3117 HDNSRLTNDGAAGVVASDGLTGHVKGDANLTGATIADLSGKGNLKVDGAVNAQN 3170
Score = 30.8 bits (68), Expect = 0.032
Identities = 53/237 (22%), Positives = 86/237 (36%), Gaps = 31/237 (13%)
Query 1642 VALLAGLAGAMQGELASQIGTHLDKVDPNVFEYAIHKIAHAAVGCAVAAATKSSCEAGAI 1701
VA L L GA+ + + N +++A + A G AAA + + A
Sbjct 234 VARLVKLQGAVSSKQGKPLADIAVVAGANRYDHATRRATPIAAGARGAAAGAYAIDGTAA 293
Query 1702 GAGVGEIVASLMPDPVNGI----EYNEDEKTKIRNTGKIV---------------AGVVS 1742
GA G+ + + D G+ + + + G+I AGVVS
Sbjct 294 GAMYGKHITLVSSDSGLGVRQLGSLSSPSAITVSSQGEIALGDATVQRGPLSLKGAGVVS 353
Query 1743 ----AYAGYDVNTAANSADIAIQNNSLVKLAT-STGKILVKTLDEFNALRKAGKQVTKDD 1797
A G VN A A +S+ LA GK+ L+ L +G+Q +
Sbjct 354 AGKLASGGGAVNVAGGGAVKIASASSVGNLAVQGGGKVQATLLNAGGTLLVSGRQAVQLG 413
Query 1798 LVTSFKKQGADELIGIADDLLTVFGRSSSSFDRALA-------AIDLIVGTDLKPGK 1847
+S + + + D L+ R +A+A A+ + G LK GK
Sbjct 414 AASSRQALSVNAGGALKADKLSATRRVDVDGKQAVALGSASSNALSVRAGGALKAGK 470
Score = 30.0 bits (66), Expect = 0.055
Identities = 28/136 (21%), Positives = 61/136 (45%), Gaps = 18/136 (13%)
Query 1100 GSIDITSSKGISISGSELISKKGLVNIEALGALSQNYT-------STIHGKDNKPKTLGA 1152
G I + + G + ++ +++ G V I A A+ ++ T S + K +K K
Sbjct 1108 GDIIMDAKGGTLLLRNDALTENGTVTISADSAVLEHSTIESKISQSVLAAKGDKGKP--- 1164
Query 1153 SIIIDGSQDFYDKG-----NENDQKYRFRTILKPTLINGDKGVTIRATGNSNQDNLVLQA 1207
++ + ++ + G N+N++ R I +++G +T TG + +D V+
Sbjct 1165 AVSVKVAKKLFLNGTLRAVNDNNETMSGRQI---DVVDGRPQITDAVTGEARKDESVVSD 1221
Query 1208 TGITAANGDVRIEANK 1223
+ A G + +EA +
Sbjct 1222 AALVADGGPIVVEAGE 1237
Score = 27.7 bits (60), Expect = 0.27
Identities = 41/151 (27%), Positives = 64/151 (42%), Gaps = 19/151 (13%)
Query 1519 VTAGAGSAVVGALGGSATTLG---GSAVVMTQA----AVTSLATQASVSLINNGGDLGKT 1571
+ AGA A GA T G G + + + V L + +S S I
Sbjct 274 IAAGARGAAAGAYAIDGTAAGAMYGKHITLVSSDSGLGVRQLGSLSSPSAITVSSQGEIA 333
Query 1572 LKDLGSKDSVKNL-AASVVTAGLLSQVGSALNLKPDTSGFSARLLNNFTTAVGSTLVQTA 1630
L D + +L A VV+AG L+ G A+N+ G + ++ + ++VG+ VQ
Sbjct 334 LGDATVQRGPLSLKGAGVVSAGKLASGGGAVNV---AGGGAVKIAS--ASSVGNLAVQ-- 386
Query 1631 IKGGDLEDNLKVALLAGLAGAMQGELASQIG 1661
GG ++ L L AG + G A Q+G
Sbjct 387 -GGGKVQATL---LNAGGTLLVSGRQAVQLG 413
Score = 27.7 bits (60), Expect = 0.27
Identities = 41/219 (19%), Positives = 83/219 (38%), Gaps = 29/219 (13%)
Query 1184 INGDKGVTIRATGNSNQDNLVLQATGITAANGDVRIEANKNILFDAAIEQSYDRSTTTEK 1243
++ G+ + G D+L + VR++ +++ A I + T
Sbjct 794 VSAKSGIGLEGWGAVGADSLGSDGAISVSGRDAVRVDQARSL---ADISLGAEGGATLGA 850
Query 1244 KSSWGGLKKKYITTVSENNQANAASVDISGKNIFIESKEKNPANNIDIYSGKFIANGGQV 1303
+ G + + +TV+ N+ V +SGK D +GG +
Sbjct 851 VEAAGSIDVRGGSTVAANSLHANRDVRVSGK---------------DAVRVTAATSGGGL 895
Query 1304 SILSGGNINLYTVQESSSSNEDITKKSSFSGIKYNTSKTNATRN----QISELPGILKAD 1359
+ SG ++L VQ + D +G+ ++K + T + + +L +
Sbjct 896 HVSSGRQLDLGAVQARGALALD-----GGAGVALQSAKASGTLHVQGGEHLDLGTLAAVG 950
Query 1360 YIGIKADNDVRLVGTEFEYLQAAKIQAGRNLSLLTASTT 1398
+ + DVR+ + A +QAGR+++L TT
Sbjct 951 AVDVNGTGDVRVAKLVSD--AGADLQAGRSMTLGIVDTT 987
Score = 25.4 bits (54), Expect = 1.4
Identities = 75/328 (23%), Positives = 121/328 (37%), Gaps = 29/328 (9%)
Query 1543 VVMTQAAVTSL---ATQASVSLINNGGDLGKTLKDLGSKDSVKNLAASVVTAGLLSQVGS 1599
V T +A +SL AT+ S+ N D G+ ++ V A +VTA + S
Sbjct 2862 VASTASARSSLLTAATRLGDSVAQNVED-GREIRGELMAAQVAAEATQLVTADTAAVALS 2920
Query 1600 ALNLKPDTSGFSARLLNNFTTAVG-----------STLVQTAIKGGDLEDNLKVALLAGL 1648
A + D +R + T +G +TLV GGD + +LK A L
Sbjct 2921 A-GISADFDSSHSRSTSQNTQYLGGNLSIEATEGDATLVGAKFGGGD-QVSLKAAKSVNL 2978
Query 1649 AGAMQG-ELASQIGTHLDKVDPNVFEYAIHKIAHAAVGCAVAAATKSSCEAGAIGAGVGE 1707
A E S+ D N+ A+ + + + + + E G AG
Sbjct 2979 MAAESTFESYSESHNFHASADANLGANAVQGAVGLGLTAGMGTSHQITNETGKTYAGTSV 3038
Query 1708 IVASLMPDPVNGIEYNEDEKTKIRNTGKIVAGVVSAYAGYD---VNTAAN----SADIAI 1760
A++ D + + + + ++ V G ++A + D N++ SA +AI
Sbjct 3039 DAANVSIDAGKDLNLS-GSRVRGKHVVLDVEGDINATSKQDERNYNSSGGGWDASAGVAI 3097
Query 1761 QNNSLVKLATSTGKILVKTLDEFNALRKAGKQVTKDDLVTSFKKQGADELIGIADDLLTV 1820
QN +LV S G D V D +T K G L G + +
Sbjct 3098 QNRTLVAPVGSAGFNFNTEHDNSRLTNDGAAGVVASDGLTGHVK-GDANLTGAT--IADL 3154
Query 1821 FGRSSSSFDRALAAIDLIVGTDLKPGKG 1848
G+ + D A+ A +L D G G
Sbjct 3155 SGKGNLKVDGAVNAQNLKDYRDKDGGSG 3182
Score = 23.5 bits (49), Expect = 5.3
Identities = 17/84 (20%), Positives = 40/84 (48%), Gaps = 7/84 (8%)
Query 837 GDLSIQTKESLTIDPNIHTLKAIG------DIELASKQGTLILAGYGGQAGNGSEKVLNL 890
G I + +T++ + H + ++ +++ + +G +++A G AG G E +
Sbjct 2499 GGALIASGGDVTVNTDGHDVSSVNGLIQGRSVKVDAGKGKVVVADSKG-AGGGIEADDEV 2557
Query 891 TTTGGGISLEGASVELQGAQLNAE 914
+G I +EG + + +L A+
Sbjct 2558 DVSGRDIGIEGGKLRGKDVRLKAD 2581
Score = 23.1 bits (48), Expect = 6.9
Identities = 21/99 (21%), Positives = 40/99 (40%), Gaps = 17/99 (17%)
Query 1730 IRNTGKIVAG----VVSAY-------------AGYDVNTAANSADIAIQNNSLVKLATST 1772
+RNTG++VAG ++++ DV N+ + ++++ + LA T
Sbjct 1611 LRNTGQVVAGHDIHIINSAKLENTGRVDARNDIALDVADFTNTGSLYAEHDATLTLAQGT 1670
Query 1773 GKILVKTLDEFNALRKAGKQVTKDDLVTSFKKQGADELI 1811
+ LV D + + +V L T + LI
Sbjct 1671 QRDLVVDQDHILPVAEGTLRVKAKSLTTEIETGNPGSLI 1709
Score = 22.7 bits (47), Expect = 9.0
Identities = 36/168 (21%), Positives = 80/168 (48%), Gaps = 17/168 (10%)
Query 1688 VAAATKSSCEAG-AIGAGVGEIVASLMPDPVNGIEYNEDE---KTKIRNTGKIVAGVVSA 1743
VAAA + +AG A+ AG + ++ + + + + + ++ + G+ G ++A
Sbjct 680 VAAAADLALQAGDALQAGFLKSAGAMTVNGRDAVRLDGAHAGGQLRVSSDGQAALGSLAA 739
Query 1744 YAGYDVNTAANSADIAIQNNSLVKLATSTG-KILVKTLDEFNALR-------KAGKQVTK 1795
V+ AA +A +A + SL ++ + G ++ V++++ + + GK K
Sbjct 740 KGELTVS-AARAATVA-ELKSLDNISVTGGERVSVQSVNSASRVAISAHGALDVGKVSAK 797
Query 1796 DDL-VTSFKKQGADELIGIADDLLTVFGRSSSSFDRALAAIDLIVGTD 1842
+ + + GAD L +D ++V GR + D+A + D+ +G +
Sbjct 798 SGIGLEGWGAVGADSLG--SDGAISVSGRDAVRVDQARSLADISLGAE 843
>C4SGN7 tRNA nuclease CdiA [Yersinia mollaretii (strain ATCC 43969
/ DSM 18520 / CIP 103324 / CNY 7263 / WAIP 204)]
Length=2963
Score = 196 bits (497), Expect = 2e-52
Identities = 280/1118 (25%), Positives = 475/1118 (42%), Gaps = 140/1118 (13%)
Query 95 GQNVPVVNIQTPTN-GVSHNIYKQMDVLPEGVVLNNSRTG-ANSSLVGTVGANPFLAKGE 152
G VPVVNI P + GVSHN+Y Q +V EGV+LNN+ + L G + +N L
Sbjct 45 GNGVPVVNIAPPNSAGVSHNVYNQFNVGSEGVILNNATDRLTQTQLGGLIQSNANLNGKA 104
Query 153 ARIILNEVNSSVASRFEGNLEVAGQRADVIIANPAGINIKGGGFINANKAILTTGKPQLN 212
A I+NEV S+ S+ G LEV G+ A V++ANP GI G GFIN LTTGKP ++
Sbjct 105 AGAIINEVVSANRSQLNGYLEVGGKAAAVMVANPYGITCDGCGFINTPNVTLTTGKPMMD 164
Query 213 ADGSIQQFVVDQGKITISANSGSSLGLGGNKNNADYVDLYARALELNAQLYANKDIQAIT 272
+G +Q V QG I+I G G + + + + L +RA E+NAQ++A +D+ I
Sbjct 165 TNGKLQSLDVTQGAISIQ-------GKGLDASQSSALSLISRANEINAQIHA-QDLTVIA 216
Query 273 GANNISADLQQISTRTGTGTTPTLAIDVKNLGGMYANNIYLLGNEKGLGVSNAGTIRA-- 330
G+N + + +S R G G P ++ID LGGMYAN I L+ +EKG+GV N G + A
Sbjct 217 GSNRVDS-AGHVSERQGQGDVPQVSIDTGALGGMYANRIRLVSSEKGVGV-NLGNLNARQ 274
Query 331 ------------VNNLV-----VTSA------GKIEHKGSLESTSNTQGLVSIQTTQTGD 367
VNN V + SA G +G++ S+ + + T GD
Sbjct 275 GDIQLDSKGKLTVNNAVAHGDIIASADQLHLQGHQRAQGNITLNSHGESRLDNATLLAGD 334
Query 368 NGNINSSGSITSKSM---LSIDAANHL------NITGNQVIVNQGVVSPLLLSAQGDINV 418
+ + G ITSK +D+A ++ ++ G+++ + Q V+ +S V
Sbjct 335 TLAVKAGGKITSKESQLNAGVDSAGNIGEKGTVSLQGSELALQQSHVAAAAVSV-----V 389
Query 419 SNGAIIKNVQTGGDIYLDAQNINV-GENTQIANVGLVNLNAAAAIDIKKSARVKAVNDLN 477
S+G I+++ ++ L A+ + + G++ ++A N + + + ++ +V
Sbjct 390 SSGDIVQDKESS----LTARQLKLSGQHLELAGQLAANNDLSITGQSLRGSKTASVGSQK 445
Query 478 IIA--KQGLSVADANLVAEKGNMNLQSNSNITLQGTTLDLT----KDLNINGTGNVNLSS 531
I G S +VA GN + S ++T G L + L ++ G + +
Sbjct 446 NITFNLAGDSEWAGQMVA--GNDLIFSGQSLTNHGQLLAANQMHFEGLGLDNQGQILAAD 503
Query 532 LNFSL--LNGSSTLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANLIDLKGSNLSGKG 589
+N ++ LN LQ + TA +L Q S T+ + + L+ + + G
Sbjct 504 INIAVHRLNNQGQLQGDKSLL-------LTADSLVQ-STRGTMNSGRALTLRAAEMDISG 555
Query 590 DLKLQGKALNVGADLTAGKSLNLTATQSDLILNKTLNAQGNIDIASLDGKLNATGLNATS 649
D LQ + L+V D + + L L T++ +G + +++ D L+ N S
Sbjct 556 D--LQSQILDVKGDNWHNHGNVVAQEHAQLRLGHTIDNRG-VLVSAGDMDLS---FNQLS 609
Query 650 SQGKLSIFGAKDTV----LTNSGTV--KTTL-----KGNQGVNVGTISTGNLTLQNTVLE 698
+QG+ I GA+ + ++NSG + K L +G QG + G + + L L T E
Sbjct 610 NQGR--ILGAELALSGKNISNSGQLVGKQQLSLQLDEGYQGTSSGELKSDGL-LSVTADE 666
Query 699 SQNGAIVVTSEGQNTLTDSIITAKGNIELFAKDNLTLDGIKSSSQQHTALNSKKNIYINS 758
N G T +T G + N+ L G ++ Q L + I +
Sbjct 667 INNQG--HWESGSLNTTAQQLTNNGKVLSVGSQNINLSGSLTNQQLGQFLTDGEFIIVAE 724
Query 759 QAGTGDSVNFSSTKITELNST-----GTLSLISDKNQNLQNTRLTGGAILLEAGGTLNTP 813
Q +S + LN GT S + K ++ A L++AG T
Sbjct 725 Q--VINSGLLQGNQAVTLNGLKQYQGGTGSQLLTKGVGEIHSDSVNNAGLIQAGSLSLTG 782
Query 814 KVIEFNAT--GSNLLKNDSKLNSLNGDLSIQTKESLTIDPNIHTLKAIGDIELASKQGTL 871
+V++ T G + L DS +N Q + L D N L + + QGT
Sbjct 783 EVLDNTGTLSGLSTLHIDSHNEIIN-----QARGQLLSD-NTIKLDSEQLVNNGLMQGTE 836
Query 872 ILAGYGGQAGNGS--------EKVLNLTTTGGGISLEGASVELQGAQLNAEKNIKILANN 923
++ NG+ + +NLT + G L G + + L L +
Sbjct 837 LVLASQHLTNNGTLLGLTYLELQAVNLTNSSAGKILSGQDLHFTTSHLQQNGQWTALRDL 896
Query 924 ENIQIISIKNKLNNSKLSDSNKLLVDLVEIDNKLKKISINNQYTELFLADVKILENAYDI 983
IK L+ S + K L +++D + N Q ++ + ++ N+ +
Sbjct 897 TG----EIKGALDFSGAMAAGKQL--SLQVDGDFNQRG-NLQGNDVSITSRGVITNSGQL 949
Query 984 AFNFNPSA-------YKEDASYRKGSDKDIQFFNEVYD-GFVKKYSDIIEPNIYSQQLNG 1035
A A ++ S + G + ++ + GFV D++ I + +N
Sbjct 950 AAGSGSLALNGAAINQEQSGSLQSGGQISLTSRGDINNRGFVGAAGDLLLQAIGA--VNN 1007
Query 1036 TKYSTQISIAVPFGDGDYARKEDILSPNGYFKYKYDQNKIRSEINYLSQLNGYEHFSSKL 1095
T D Y + DIL+ N + + + EI ++ E +
Sbjct 1008 TSLLYAGGSMRLLADAIYNVRGDILAGNHLWMQRDNAGNSNREI--INSSGNIETQQGDM 1065
Query 1096 VSNSGSIDITSSKGISIS-GSELISKKGLVNIEALGAL 1132
V N+ S+ + G S++ + ++ G+ N+ A L
Sbjct 1066 VLNTASL-LNRRDGFSVTEKTGAVNSGGIANVGATNIL 1102
Score = 78.2 bits (191), Expect = 1e-16
Identities = 247/1256 (20%), Positives = 474/1256 (38%), Gaps = 181/1256 (14%)
Query 255 ALELNAQLYANKDIQAITGANNI----SADLQQISTRTGTGTTPTLAIDVKNLGGMYANN 310
+L AQ N G+ NI S QQ+ G +A V N G + N
Sbjct 677 SLNTTAQQLTNNGKVLSVGSQNINLSGSLTNQQLGQFLTDGEFIIVAEQVINSGLLQGNQ 736
Query 311 IYLLGNEK----GLG----VSNAGTIRA--VNNLVVTSAGKIEHKGS-LESTSNTQGLVS 359
L K G G G I + VNN + AG + G L++T GL +
Sbjct 737 AVTLNGLKQYQGGTGSQLLTKGVGEIHSDSVNNAGLIQAGSLSLTGEVLDNTGTLSGLST 796
Query 360 IQTTQTGDNGNINSSGSITSKSMLSIDAANHLN---------ITGNQVIVNQGVVSPLLL 410
+ + N + G + S + + +D+ +N + +Q + N G + L
Sbjct 797 LHIDSHNEIIN-QARGQLLSDNTIKLDSEQLVNNGLMQGTELVLASQHLTNNGTLLGLTY 855
Query 411 SAQGDINVSNGAIIKNVQTGGDIYLDAQNINV-GENTQIANV-----GLVNLNAAAAIDI 464
+N++N + K + +G D++ ++ G+ T + ++ G ++ + A A
Sbjct 856 LELQAVNLTNSSAGK-ILSGQDLHFTTSHLQQNGQWTALRDLTGEIKGALDFSGAMAAGK 914
Query 465 KKSARVKA-VNDLNIIAKQGLSVADANLVAEKGNMNLQSNSNITLQGTTLDLTKDLNING 523
+ S +V N + +S+ ++ G + S S + L G ++ + ++
Sbjct 915 QLSLQVDGDFNQRGNLQGNDVSITSRGVITNSGQLAAGSGS-LALNGAAINQEQSGSLQS 973
Query 524 TGNVNLSSLN------FSLLNGSSTLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANL 577
G ++L+S F G LQ I A + +L++ G++ L A +
Sbjct 974 GGQISLTSRGDINNRGFVGAAGDLLLQAIGAVNNTSLLY---------AGGSMRLLADAI 1024
Query 578 IDLKGSNLSGKGDLKLQGKALNVGADLTAGKSLNLTATQSDLILNKT--LNAQGNIDIAS 635
+++G L+G + A N ++ S N+ Q D++LN LN + +
Sbjct 1025 YNVRGDILAGNHLWMQRDNAGNSNREII-NSSGNIETQQGDMVLNTASLLNRRDGFSVTE 1083
Query 636 LDGKLNATGL-NATSSQGKLSIFGAKDTVLTNSGTVKTTLKGNQGVNVGTISTGNLTLQN 694
G +N+ G+ N ++ +S K +T+ KT G NV T++ L
Sbjct 1084 KTGAVNSGGIANVGATNILISSGYFKPGEVTHYS--KTVTGGGHHGNVSTVNLLGLVPSA 1141
Query 695 TVLESQNGAIVVTSEGQNTLTDSIITAKGNI----------ELFAKDNLTLDGIKSSSQQ 744
+ + +VT + + + NI ++ A N L G ++Q
Sbjct 1142 RKQKLSTSSSIVTVDSPYDVGRIVAGRDINISANTLVNQASQMSAGRNALLQGQSLNNQS 1201
Query 745 HTALNSKKNIYINSQAGTGDSVNFSSTKIT-----ELNSTGTL---------SLISDKNQ 790
+ + + + + T N K++ E+++ G L S+ ++ Q
Sbjct 1202 YQSGTLTQYLVYTNTRDTNPEYNLFEFKLSGSPTYEISNDGQLYQGVIQAVGSVSANFTQ 1261
Query 791 NLQNTRLT---GGAILLEAGGTLNTPKVIEFNATGSNLLKNDSKLNSLNGDLSIQTKES- 846
NL NT + G + +L V AT N +S NGDL +S
Sbjct 1262 NLSNTSVKPNIGSIVHQVTQPSLTATTVPSELATKPNSGAAQVAPDSNNGDLVALYNQSG 1321
Query 847 ------LTIDPNIHTLKAIGDIELASKQGTLILAGYGGQAGNGSEKVLNLTTTGGGISLE 900
L D T + D L L + + GS +++ T LE
Sbjct 1322 TALTFGLGTDGKPLTRAQLSDYPLPDSNNGLFVVN----SEPGSRYLISTNPT-----LE 1372
Query 901 GASVELQGAQLNAEKNIKILANNENIQIISIKNKLNNSKLSDSNKLLVDLVEIDNKLKKI 960
+L ++ + + ++I+ N + + + L D LKKI
Sbjct 1373 ----KLGNVDSTLLSGLQAMLGRQPQTSVAIER---NPQWTQQDNFLGS----DYLLKKI 1421
Query 961 SINNQYTELFLADVKILENAYDIAFNFNPSAYKEDASYRKGSDKDIQFFNEVYDGFV--- 1017
+++ ++ FL D A+D + N + Y G D+ + D
Sbjct 1422 NLDAEHDYRFLGDA-----AFDTRYINNAVLSQTGQRYLNGVGSDLSQMQYLLDNAAQSQ 1476
Query 1018 KKYSDIIEPNIYSQQLNGTKYSTQISIAVPFGDGDYARKEDILSPNGYFKYKYDQNKIRS 1077
KK + ++ +Q+ Q+S ++ + + + +L+P Y K +Q ++
Sbjct 1477 KKLDLKLGVSLTPEQV------AQLSHSIVWWENINVNGQTVLAPKLYLA-KAEQAHLQG 1529
Query 1078 EI--NYLSQLNGYEHFSSKLVSNSGSIDITSSKGISISGSELISKKGLVNIEALGALSQN 1135
+ +LN +S ++ + I S I+ L++ +G +N+ AL +S N
Sbjct 1530 SVISGNKVELNAGSVTNSGVLKGVELLAIASQDTITNEKGGLLTSEGALNLTALNNIS-N 1588
Query 1136 YTSTIHGKDNKPKTLGASIIIDGSQDFYDKGNENDQKYRFRTILKPTLINGDKGVTIRAT 1195
+S+I G D T II+ +Q +++ Q + I ++ + G T T
Sbjct 1589 LSSSISG-DRVAITSQNGDIINQTQTRQWSADQSRQPGYWSGIKTQSMTQTEVGETAAIT 1647
Query 1196 GN-----SNQDNLVLQATGITAANGDVRIEANKNILFDA-----AIEQSYDRSTTTEKKS 1245
+ +N+ + +TAA GD+ I+A +I A A +Q+ R+ E
Sbjct 1648 AGKALTLAAGNNIAITGAKVTAA-GDIGIQAAHDINIIANDLYSAQQQTLGRNRNIELNE 1706
Query 1246 ---------SWGGLKKKYI----------------TTVSENNQANAASVDISGKNIFIES 1280
S GG + T+ N + S +N I+S
Sbjct 1707 QHESQSSHVSAGGTLTAHAGRDITLSASHLGADGNATLQAERDVNLLVQEKSTRNQHIDS 1766
Query 1281 KEKNPANNIDIYSGKFIANGGQVSILSGGNINLYTVQESSSSNEDITKKSSFSGIKYNTS 1340
++K Y+ +++GG ++ +G +IN Q ++ + E+ ++ I N
Sbjct 1767 EDKTTG-----YTRSTLSSGGDLTASAGRDINS---QAAAVTAENTLALNAGRDINLNAQ 1818
Query 1341 KTNATRNQISELPGILKADYIGIKADNDVRLVGTEFEYLQAAKIQAGRNLSLLTAS 1396
++ Q +E G +Y + D +R GTE + ++ AG++++L AS
Sbjct 1819 ESR----QYNESHG---KNYK--RVDEAIRQQGTELASGKGTQVHAGQDINLHAAS 1865
Score = 57.8 bits (138), Expect = 2e-10
Identities = 140/683 (20%), Positives = 263/683 (39%), Gaps = 113/683 (17%)
Query 314 LGNEKGLGVSNAGTIRAVNNLV-----VTSAGKIEHKGSLESTSNTQGLVSIQTTQTGDN 368
+G + A T+ A NN+ VT+AG I + + + L S Q G N
Sbjct 1640 VGETAAITAGKALTLAAGNNIAITGAKVTAAGDIGIQAAHDINIIANDLYSAQQQTLGRN 1699
Query 369 GNI-------------NSSGSITSKSMLSID-AANHLNITGNQVIVNQGVVSPLLLSAQG 414
NI ++ G++T+ + I +A+HL GN + + V+ LL+ +
Sbjct 1700 RNIELNEQHESQSSHVSAGGTLTAHAGRDITLSASHLGADGNATLQAERDVN-LLVQEKS 1758
Query 415 DINV-------SNGAIIKNVQTGGDIYLDA-QNIN------VGENTQIANVGL-VNLNAA 459
N + G + +GGD+ A ++IN ENT N G +NLNA
Sbjct 1759 TRNQHIDSEDKTTGYTRSTLSSGGDLTASAGRDINSQAAAVTAENTLALNAGRDINLNAQ 1818
Query 460 AAIDIKKSARVKAVNDLNIIAKQGLSVADANLVAEKGNMNLQSNSNITLQGTTLDLTKDL 519
+ +S I +QG +A KG + + +I L ++ DL
Sbjct 1819 ESRQYNESHGKNYKRVDEAIRQQGTELASG-----KGTQ-VHAGQDINLHAASISAKGDL 1872
Query 520 NINGTGNVNLSSL---NFSLLNGSSTLQNINAYSGLNLVWDQ---TAKALPQISGNVTLE 573
+ ++ ++S ++ T + + + + ++ V + T K+ + NV+L
Sbjct 1873 ALQAGRDIAVNSATESDYHFFEEKKTKKKLVSKTTIHNVEEDFATTEKSSALVGNNVSLS 1932
Query 574 AANLIDLKGSNLSGKGDLKLQGKALNVGADLTAGKSLNLTATQSDLILNKTLNAQGNIDI 633
A N + +KGS++ G G + L A N+DI
Sbjct 1933 AGNNLIVKGSSVVGDGTV--------------------------------VLKADNNVDI 1960
Query 634 ASLDGKLNATGLNATSSQGKLSIFGAKDTVLTNSGTVKTTLKG---NQGVNVGTISTGNL 690
+ + ++ LN + G S G T+ + S + +G ++ + + GN+
Sbjct 1961 VAATEQQSSYRLNEKKTSGMFSGGGLGVTLGSKSSRQQINQEGSKQSESASAVGSTAGNV 2020
Query 691 TLQNTVLESQNGAIVVTSEGQNTLTDSIITAKGNIELFAK-------DNLTLDGIKSSSQ 743
++ +G+ V+ + N + +I GN L + LTL +
Sbjct 2021 SILAGAQAHISGSDVIAGKDLNVIAGTIKVDPGNDVLKRRQIYEQKQSGLTLSLSSPFTD 2080
Query 744 QHTALNSKKNIYINSQAGTGD-SVNFSSTKITE--LNSTGTLSLISDKNQNLQNTRLTGG 800
A+NSK + S AG+ S + + E + GT+ +++ K G
Sbjct 2081 ALLAINSK--LKQASDAGSDKLSALYGAQAAREAWVGVDGTMDMMASKPGG--PAADPGA 2136
Query 801 AILLE----AGGTLNTPKVIEFNATGSNLLKNDSKLNSLNGDLSIQTKESLT---IDPNI 853
+I L+ A + +T ++ + GS+L D+ +GD S+ + N
Sbjct 2137 SIKLQLSVGASHSKSTSELAQNQTRGSSLTAGDNLTMVASGDHEQSGDLSVVGSGVTGNK 2196
Query 854 HTLKAIGDIELASKQGTLILAGYGGQAGNGSEKVLNL-TTTGGGISL---------EGAS 903
TL A D+ LA+ +G + L+L TG GI+ +G +
Sbjct 2197 VTLVAKNDVLLAAASNNSEQTSRDSSSGWNAGVHLSLGKETGIGIAANGFMSKGNSDGKT 2256
Query 904 VELQGAQLNAEKNIKILANNENI 926
+ A++NA++ + I + + +
Sbjct 2257 TDYANARINAKEALAINSGRDTV 2279
Score = 57.4 bits (137), Expect = 3e-10
Identities = 137/653 (21%), Positives = 248/653 (38%), Gaps = 118/653 (18%)
Query 333 NLVVTSAGKIEHKGSLESTSNTQGLVSIQTTQTGDNGNINSSGSITSKSMLSIDAANHLN 392
N V +AG + + G L+ ++ Q T T + G G +TS+ L++ A N+
Sbjct 1535 NKVELNAGSVTNSGVLKGVELLA--IASQDTITNEKG-----GLLTSEGALNLTALNN-- 1585
Query 393 ITGNQVIVNQGVVSPLLLSAQGD---INVSNGAIIKNVQTGGDIYLDAQNINVGENTQIA 449
+S L S GD I NG II QT + + ++ Q
Sbjct 1586 ------------ISNLSSSISGDRVAITSQNGDIINQTQT--------RQWSADQSRQPG 1625
Query 450 NVGLVNLNAAAAIDIKKSARVKAVNDLNIIAKQGLSVADANLVAEKGNMNLQSNSNITLQ 509
+ + ++ ++A + A L + A +++ A + A G++ +Q+ +I +
Sbjct 1626 YWSGIKTQSMTQTEVGETAAITAGKALTLAAGNNIAITGAKVTA-AGDIGIQAAHDINII 1684
Query 510 GTTLDLTKDLNINGTGNVNLSSLNFSLLNGSSTLQNINAYSGLNLVWDQTAKALPQISGN 569
L + + N+ L+ + S Q+ + +G G
Sbjct 1685 ANDLYSAQQQTLGRNRNIELNEQHES--------QSSHVSAG----------------GT 1720
Query 570 VTLEAANLIDLKGSNLSGKGDLKLQGKALNVGADLTAGKSLNLTATQSDLILNKTLNAQG 629
+T A I L S+L G+ LQ A + +NL L+ K+ Q
Sbjct 1721 LTAHAGRDITLSASHLGADGNATLQ-----------AERDVNL------LVQEKSTRNQ- 1762
Query 630 NIDIASLDGKLNATGL--NATSSQGKLSIFGAKDTVLTNSGTVKTTLKGNQGVNVGTIST 687
+D + TG + SS G L+ +D NS T + +N G
Sbjct 1763 -----HIDSEDKTTGYTRSTLSSGGDLTASAGRD---INSQAAAVTAENTLALNAGRDIN 1814
Query 688 GNLTLQNTVLESQNGAIVVTSEGQNTLTDSIITAKGNIELFAKDNLTLDGIKSSSQQHTA 747
N ES E + + KG ++ A ++ L S++ A
Sbjct 1815 LNAQESRQYNESHGKNYKRVDEAIRQQGTELASGKGT-QVHAGQDINLHAASISAKGDLA 1873
Query 748 LNSKKNIYINSQAGTGDSVNFSSTKITE---LNSTGTLSLISDKNQNLQNTRLTGGAILL 804
L + ++I +NS T +F K T+ ++ T ++ D +++ L G + L
Sbjct 1874 LQAGRDIAVNS--ATESDYHFFEEKKTKKKLVSKTTIHNVEEDFATTEKSSALVGNNVSL 1931
Query 805 EAGGTLNTPKVIEFNATGSNLLKNDSKLNSLNGDLSIQTKESLTIDPNIHTLKAIG---- 860
AG L K G+ +LK D+ N D+ T++ + ++ K G
Sbjct 1932 SAGNNL-IVKGSSVVGDGTVVLKADN-----NVDIVAATEQQSSY--RLNEKKTSGMFSG 1983
Query 861 ---DIELASKQGTLILAGYGGQAGNGSEKVLNLTTTGGGIS-LEGASVELQGAQLNAEKN 916
+ L SK + G + SE + +T G +S L GA + G+ + A K+
Sbjct 1984 GGLGVTLGSKSSRQQINQEGSKQ---SESASAVGSTAGNVSILAGAQAHISGSDVIAGKD 2040
Query 917 IKILA-------NNENIQIISI-KNKLNNSKLSDSNKLLVDLVEIDNKLKKIS 961
+ ++A N+ ++ I + K + LS S+ L+ I++KLK+ S
Sbjct 2041 LNVIAGTIKVDPGNDVLKRRQIYEQKQSGLTLSLSSPFTDALLAINSKLKQAS 2093
Score = 54.3 bits (129), Expect = 2e-09
Identities = 135/665 (20%), Positives = 262/665 (39%), Gaps = 105/665 (16%)
Query 308 ANNIYLLGNEKGLGVSNAGTIRAVNNLVVTSAGKIEHKGSLESTSNTQGLVSIQTTQTGD 367
A N+ L N L S +G A+ + + + + S G S TQ+
Sbjct 1577 ALNLTALNNISNLSSSISGDRVAITSQNGDIINQTQTRQWSADQSRQPGYWSGIKTQSMT 1636
Query 368 NGNINSSGSITSKSMLSIDAANHLNITGNQVIVNQGVVSPLLLSAQGDIN-VSNGAIIKN 426
+ + +IT+ L++ A N++ ITG +V + + A DIN ++N
Sbjct 1637 QTEVGETAAITAGKALTLAAGNNIAITGAKVT----AAGDIGIQAAHDINIIANDLYSAQ 1692
Query 427 VQT-GGDIYLDAQNINVGENTQIANVGLVNLNAAAAIDIKKS-------ARVKAVNDLNI 478
QT G + ++ + +++ ++ G + +A I + S A ++A D+N+
Sbjct 1693 QQTLGRNRNIELNEQHESQSSHVSAGGTLTAHAGRDITLSASHLGADGNATLQAERDVNL 1752
Query 479 IAK------QGLSVAD------ANLVAEKGNMNLQSNSNITLQGTTLDLTKDLNINGTGN 526
+ + Q + D + ++ G++ + +I Q + L +N +
Sbjct 1753 LVQEKSTRNQHIDSEDKTTGYTRSTLSSGGDLTASAGRDINSQAAAVTAENTLALNAGRD 1812
Query 527 VNLSSLNFSLLNGSSTLQNINAYSGLNLVWDQTAKALPQISGNVTLEAANLIDLKGSNLS 586
+NL++ N S + Y ++ Q L G + A I+L +++S
Sbjct 1813 INLNAQESRQYNES----HGKNYKRVDEAIRQQGTELASGKG-TQVHAGQDINLHAASIS 1867
Query 587 GKGDLKLQGKALNVGADLTAGKSLNLTATQSDL-----------ILNKTLNAQGNIDIAS 635
KGDL AL G D+ +AT+SD +++KT D A+
Sbjct 1868 AKGDL-----ALQAGRDIAVN-----SATESDYHFFEEKKTKKKLVSKTTIHNVEEDFAT 1917
Query 636 LDGKLNATGLNATSSQGKLSIFGAKDTVLTNSGTVKTTLKGNQGVNVGTISTGNLTLQNT 695
+ G N + S G I +KG+ V GT+
Sbjct 1918 TEKSSALVGNNVSLSAGNNLI-----------------VKGSSVVGDGTV---------- 1950
Query 696 VLESQNGA-IVVTSEGQNTLTDSIITAKGNIELFAKDNLTLD-GIKSSSQQHTALNSKKN 753
VL++ N IV +E Q++ + K +F+ L + G KSS QQ SK++
Sbjct 1951 VLKADNNVDIVAATEQQSSYR---LNEKKTSGMFSGGGLGVTLGSKSSRQQINQEGSKQS 2007
Query 754 IYINSQAGTGDSVNFSSTKITELNSTGTLSLISDKNQNLQNTRLTGGAILLEAGG-TLNT 812
++ T +V+ + ++ + +I+ K+ N + G I ++ G L
Sbjct 2008 ESASAVGSTAGNVSILAGAQAHISGS---DVIAGKDLN-----VIAGTIKVDPGNDVLKR 2059
Query 813 PKVIEFNATGSNLLKNDSKLNSLNGDLSIQTKESLTIDPNIHTLKAIGDIELASK----- 867
++ E +G L + ++L L+I +K D L A+ + A +
Sbjct 2060 RQIYEQKQSGLTLSLSSPFTDAL---LAINSKLKQASDAGSDKLSALYGAQAAREAWVGV 2116
Query 868 QGT--LILAGYGGQAGNGSEKV---LNLTTTGGGISLEGASVELQGAQLNAEKNIKILAN 922
GT ++ + GG A + + L++ + + E A + +G+ L A N+ ++A+
Sbjct 2117 DGTMDMMASKPGGPAADPGASIKLQLSVGASHSKSTSELAQNQTRGSSLTAGDNLTMVAS 2176
Query 923 NENIQ 927
++ Q
Sbjct 2177 GDHEQ 2181
Score = 47.0 bits (110), Expect = 4e-07
Identities = 42/140 (30%), Positives = 67/140 (48%), Gaps = 18/140 (13%)
Query 1643 ALLAGLAG----------AMQGELASQIGTHLDKVDPNVFEYAIHKIAHAAVGCAVAAAT 1692
A L GLAG A+ LA QI + D V + I+ +AHA +G VA
Sbjct 2561 AALTGLAGNADIGSISSAAVAPYLAGQIKKYTTDKDDKVNK-TINILAHAILGGIVAQMQ 2619
Query 1693 KSSCEAGAIGAGVGEIVASLMPDPVNG----IEYNEDEKTKIRNTGKIVAGV---VSAYA 1745
+S AGA+G G GE+ A + D V+ + +E +K + G + AG+ +S +
Sbjct 2620 GNSATAGALGGGGGELAARIYMDQVHPGKKVSDLSEADKKIVSAIGTLTAGILGGLSTDS 2679
Query 1746 GYDVNTAANSADIAIQNNSL 1765
+ T A + A+++N+L
Sbjct 2680 STGLITGAQAGKNAVEDNNL 2699
Score = 44.7 bits (104), Expect = 2e-06
Identities = 135/625 (22%), Positives = 248/625 (40%), Gaps = 116/625 (19%)
Query 161 NSSVASRFEGNLEVAGQRADVIIANPAGINIKGGGFINANKAILTTGKPQLNADGSIQQF 220
N V S N+ ++G + G + G FI + ++ +G Q N Q
Sbjct 688 NGKVLSVGSQNINLSGSLTN----QQLGQFLTDGEFIIVAEQVINSGLLQGN------QA 737
Query 221 VVDQGKITISANSGSSL---GLG----GNKNNADYVDLYARALELNAQLYANKDIQAITG 273
V G +GS L G+G + NNA + A +L L ++ N ++G
Sbjct 738 VTLNGLKQYQGGTGSQLLTKGVGEIHSDSVNNAGLIQ--AGSLSLTGEVLDNTG--TLSG 793
Query 274 ANNISADLQQISTRTGTG---TTPTLAIDVKNLGGMYANNIYLLGNEKGLG---VSNAGT 327
+ + D G + T+ +D + L NN + G E L ++N GT
Sbjct 794 LSTLHIDSHNEIINQARGQLLSDNTIKLDSEQL----VNNGLMQGTELVLASQHLTNNGT 849
Query 328 IRAVN-------NLVVTSAGKIEHKGSLESTSN---TQGLVSIQTTQTGD-NGNINSSGS 376
+ + NL +SAGKI L T++ G + TG+ G ++ SG+
Sbjct 850 LLGLTYLELQAVNLTNSSAGKILSGQDLHFTTSHLQQNGQWTALRDLTGEIKGALDFSGA 909
Query 377 ITSKSMLSI----DAANHLNITGNQV-IVNQGVV--SPLLLSAQGDINVSNGAIIK---- 425
+ + LS+ D N+ GN V I ++GV+ S L + G + ++ AI +
Sbjct 910 MAAGKQLSLQVDGDFNQRGNLQGNDVSITSRGVITNSGQLAAGSGSLALNGAAINQEQSG 969
Query 426 NVQTGGDIYLDAQN-------INVGENTQIANVGLVN----LNAAAAIDIKKSARVKAVN 474
++Q+GG I L ++ + + + +G VN L A ++ + A
Sbjct 970 SLQSGGQISLTSRGDINNRGFVGAAGDLLLQAIGAVNNTSLLYAGGSMRLLADAIYNVRG 1029
Query 475 DL---NIIAKQGLSVADAN--LVAEKGNMNLQSNSNITLQGTTL---------DLTKDLN 520
D+ N + Q + ++N ++ GN+ Q + + L + T +N
Sbjct 1030 DILAGNHLWMQRDNAGNSNREIINSSGNIETQQGDMVLNTASLLNRRDGFSVTEKTGAVN 1089
Query 521 INGTGNVNLSSLNFS--------------LLNGSSTLQNINAYSGLNLVWDQTAKALPQI 566
G NV +++ S + G N++ + L LV + L
Sbjct 1090 SGGIANVGATNILISSGYFKPGEVTHYSKTVTGGGHHGNVSTVNLLGLVPSARKQKLSTS 1149
Query 567 SGNVTLEAANLIDLKGSNLSGKGDLKLQGKALNVGADLTAGKSLNLTATQSDLILNKTLN 626
S VT+++ + G + + G+ +N+ A+ ++ ++A ++ L+ ++LN
Sbjct 1150 SSIVTVDSPYDV----------GRI-VAGRDINISANTLVNQASQMSAGRNALLQGQSLN 1198
Query 627 AQGNIDIASLDGKLNATGLNATSSQGKLSIF---GAKDTVLTNSGTVKTTLKGNQGV--N 681
Q + +L L T T+ + L F G+ ++N G + QGV
Sbjct 1199 NQ-SYQSGTLTQYLVYTNTRDTNPEYNLFEFKLSGSPTYEISNDGQL------YQGVIQA 1251
Query 682 VGTISTG-NLTLQNTVLESQNGAIV 705
VG++S L NT ++ G+IV
Sbjct 1252 VGSVSANFTQNLSNTSVKPNIGSIV 1276
Score = 37.4 bits (85), Expect = 3e-04
Identities = 87/389 (22%), Positives = 148/389 (38%), Gaps = 56/389 (14%)
Query 306 MYANNIYL-LGNE---KGLGVSNAGTI--RAVNNLVVTSAGKIEHKGSLESTSNTQGLVS 359
+ NN+ L GN KG V GT+ +A NN+ + +A + + L T G+ S
Sbjct 1924 LVGNNVSLSAGNNLIVKGSSVVGDGTVVLKADNNVDIVAATEQQSSYRLNE-KKTSGMFS 1982
Query 360 -----IQTTQTGDNGNINSSGSITSKSM---------LSIDAANHLNITGNQVIVNQGVV 405
+ IN GS S+S +SI A +I+G+ VI +
Sbjct 1983 GGGLGVTLGSKSSRQQINQEGSKQSESASAVGSTAGNVSILAGAQAHISGSDVIAGK--- 2039
Query 406 SPLLLSAQGDINVSNGAIIKNVQTGGDIYLDAQNINVGENTQIANVGLVNLNAAAAIDIK 465
D+NV G I V G D+ Q ++ ++ +A AI+ K
Sbjct 2040 ---------DLNVIAGTI--KVDPGNDVLKRRQIYEQKQSGLTLSLSSPFTDALLAINSK 2088
Query 466 KSARVKAVNDLNIIAKQGLSVADANLVAEKGNMNLQSNSN---ITLQGTTLDLTKDLNIN 522
A +D + A G A V G M++ ++ G ++ L L++
Sbjct 2089 LKQASDAGSD-KLSALYGAQAAREAWVGVDGTMDMMASKPGGPAADPGASIKL--QLSVG 2145
Query 523 GTGNVNLSSLNFSLLNGSSTLQNIN---AYSGLNLVWDQTAKALPQISGN-VTLEAANLI 578
+ + + S L + GSS N SG + + ++GN VTL A N +
Sbjct 2146 ASHSKSTSELAQNQTRGSSLTAGDNLTMVASGDHEQSGDLSVVGSGVTGNKVTLVAKNDV 2205
Query 579 DLKGSNLSGKGDLKLQGKALNVGADLTAGKSLNLTATQSDLILNKTLNAQGNIDIASLDG 638
L ++ + + + N G L+ GK + + A G + + DG
Sbjct 2206 LLAAASNNSEQTSRDSSSGWNAGVHLSLGKETGIG-----------IAANGFMSKGNSDG 2254
Query 639 KLNATGLNATSSQGKLSIFGAKDTVLTNS 667
K +++ L+I +DTVL+ +
Sbjct 2255 KTTDYANARINAKEALAINSGRDTVLSGA 2283
Score = 36.6 bits (83), Expect = 6e-04
Identities = 240/1188 (20%), Positives = 446/1188 (38%), Gaps = 199/1188 (17%)
Query 255 ALELNAQLYANKDIQAITGANNISADLQQISTRTGTGTTPTLAIDVKNLGGMYANNIYLL 314
AL+ + + A K + + D Q G + T + N G + A + L
Sbjct 903 ALDFSGAMAAGKQLSL-----QVDGDFNQRGNLQGNDVSITSRGVITNSGQLAAGSGSLA 957
Query 315 GNEKGLGVSNAGTIRAVNNLVVTSAGKIEHKG-----------SLESTSNTQGLVSIQTT 363
N + +G++++ + +TS G I ++G ++ + +NT L + +
Sbjct 958 LNGAAINQEQSGSLQSGGQISLTSRGDINNRGFVGAAGDLLLQAIGAVNNTSLLYAGGSM 1017
Query 364 QTGDNGNINSSGSITSKSMLSIDAANHLNITGNQVIVNQGVVSPLLLSAQGDINVSNGAI 423
+ + N G I + + L + N N N+ I+N S + + QGD+ V N A
Sbjct 1018 RLLADAIYNVRGDILAGNHLWMQRDNAGN--SNREIINS---SGNIETQQGDM-VLNTAS 1071
Query 424 IKNVQTGGDIYLDAQNINVGENTQIANVGLVNLNAAAAIDIKKSARVKAVNDLNIIAKQG 483
+ N + G + +N G IANVG N+ ++ K V +
Sbjct 1072 LLNRRDGFSVTEKTGAVNSGG---IANVGATNILISSGYF--KPGEVTHYSKTVTGGGHH 1126
Query 484 LSVADANL---VAEKGNMNLQSNSNITLQGTTLDLTK-----DLNINGTGNVN----LSS 531
+V+ NL V L ++S+I + D+ + D+NI+ VN +S+
Sbjct 1127 GNVSTVNLLGLVPSARKQKLSTSSSIVTVDSPYDVGRIVAGRDINISANTLVNQASQMSA 1186
Query 532 LNFSLLNGSSTLQNINAYSGL---NLVWDQTAKALPQISGNVTLEAANLIDLKGSN---- 584
+LL G S L N + SG LV+ T P+ NL + K S
Sbjct 1187 GRNALLQGQS-LNNQSYQSGTLTQYLVYTNTRDTNPEY---------NLFEFKLSGSPTY 1236
Query 585 -LSGKGDLKLQGKALNVGADLTAGKSLNLTATQSDLILNKTLN--AQGNIDIASLDGKLN 641
+S G L QG VG+ ++A + NL+ T + ++ Q ++ ++ +L
Sbjct 1237 EISNDGQL-YQGVIQAVGS-VSANFTQNLSNTSVKPNIGSIVHQVTQPSLTATTVPSELA 1294
Query 642 ATGLNATSSQGKLSIFGAKDTVLTNSGTVKTTLKGNQGVNVGTISTGNLTLQNTVLESQN 701
+ + S G + SGT T G G + + L +S N
Sbjct 1295 TKPNSGAAQVAPDSNNGDLVALYNQSGTALTFGLGTDGKPLTRAQLSDYPLP----DSNN 1350
Query 702 GAIVVTSE-GQNTL--TDSIITAKGNIELFAKDNLTLDGIKS--SSQQHTALNSKKNIYI 756
G VV SE G L T+ + GN+ D+ L G+++ Q T++ ++N
Sbjct 1351 GLFVVNSEPGSRYLISTNPTLEKLGNV-----DSTLLSGLQAMLGRQPQTSVAIERNPQW 1405
Query 757 NSQAG-TGDSVNFSSTKITELNSTGTLSLISDKNQNLQNTRL--TGGAILLEAGGTLNTP 813
Q G + + L + + + N L TG L G L+
Sbjct 1406 TQQDNFLGSDYLLKKINLDAEHDYRFLGDAAFDTRYINNAVLSQTGQRYLNGVGSDLSQM 1465
Query 814 KVIEFNATGSNLLKNDSKLN-SLNGDLSIQTKESLT----IDPNIHTLKA----IGDIEL 864
+ + NA S K D KL SL + Q S+ I+ N T+ A + E
Sbjct 1466 QYLLDNAAQSQK-KLDLKLGVSLTPEQVAQLSHSIVWWENINVNGQTVLAPKLYLAKAEQ 1524
Query 865 ASKQGTLILAGYGGQAGNGSEKVLNLTTTGGGISLEGASVELQGAQLNAEKNIKILANNE 924
A QG++I +G++ LN G ++ G L+G +L A + + N +
Sbjct 1525 AHLQGSVI---------SGNKVELN----AGSVTNSGV---LKGVELLAIASQDTITNEK 1568
Query 925 NIQIISIKNKLNNSKLSD----SNKLLVDLVEIDNKLKKISINNQYTELFLADVKILENA 980
+++ + LN + L++ S+ + D V I ++ I IN T + AD
Sbjct 1569 G-GLLTSEGALNLTALNNISNLSSSISGDRVAITSQNGDI-INQTQTRQWSADQSRQPGY 1626
Query 981 YD--IAFNFNPSAYKEDASYRKGSDKDIQFFNEVYDGFVKKYSDIIEPNIYSQQLNGTKY 1038
+ + + E A+ G + N + + G K
Sbjct 1627 WSGIKTQSMTQTEVGETAAITAGKALTLAAGNNI-------------------AITGAKV 1667
Query 1039 STQISIAVPFGDGDYARKEDILSPNGYFKYKYDQNKIRSEINYLSQLNGYEHFSSKLVSN 1098
+ I + A +I++ + Y + + R+ +LN S VS
Sbjct 1668 TAAGDIGI-----QAAHDINIIANDLYSAQQQTLGRNRN-----IELNEQHESQSSHVSA 1717
Query 1099 SGSIDITSSKGISISGSELISKKGLVNIEA---LGALSQNYTSTIHGKDNKPKTLGASII 1155
G++ + + I++S S L G ++A + L Q ++ D++ KT G +
Sbjct 1718 GGTLTAHAGRDITLSASHL-GADGNATLQAERDVNLLVQEKSTRNQHIDSEDKTTGYT-- 1774
Query 1156 IDGSQDFYDKGNENDQKYRFRTILKPTLINGDKGVTIRATGNSNQDNLVLQATGITAANG 1215
+ TL +G T ++ +D + QA +TA N
Sbjct 1775 ------------------------RSTLSSGGD-----LTASAGRD-INSQAAAVTAEN- 1803
Query 1216 DVRIEANKNILFDAAIEQSYDRSTTTEKKSSWGGLKKKYITTVS-ENNQANAASVDISGK 1274
+ + A ++I +A + Y+ S K ++++ S + Q +A G+
Sbjct 1804 TLALNAGRDINLNAQESRQYNESHGKNYKRVDEAIRQQGTELASGKGTQVHA------GQ 1857
Query 1275 NIFIESKEKNPANNIDIYSGKFIANGGQVSILSGGNINLYTVQESSSS----------NE 1324
+I + + + ++ + +G+ IA V+ + + + + +++ E
Sbjct 1858 DINLHAASISAKGDLALQAGRDIA----VNSATESDYHFFEEKKTKKKLVSKTTIHNVEE 1913
Query 1325 DITKKSSFSGIKYNTSKTNATRNQISELPGILKADYIGIKADNDVRLV 1372
D S + N +A N I + ++ + +KADN+V +V
Sbjct 1914 DFATTEKSSALVGNNVSLSAGNNLIVKGSSVVGDGTVVLKADNNVDIV 1961
Score = 27.3 bits (59), Expect = 0.36
Identities = 23/95 (24%), Positives = 37/95 (39%), Gaps = 7/95 (7%)
Query 1729 KIRNTGKIVAGVVSAYAGYDVNTAANSADIAIQNN--SLVKLATSTGKILVKTLDEFNAL 1786
+I N G++ GV+ A N N ++ +++ N S+V T E
Sbjct 1237 EISNDGQLYQGVIQAVGSVSANFTQNLSNTSVKPNIGSIVHQVTQPSLTATTVPSELATK 1296
Query 1787 RKAG-KQVTKD----DLVTSFKKQGADELIGIADD 1816
+G QV D DLV + + G G+ D
Sbjct 1297 PNSGAAQVAPDSNNGDLVALYNQSGTALTFGLGTD 1331
Lambda K H a alpha
0.310 0.129 0.345 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 61039652
Database: 250d27764c932d43552d88b924e9ed70.SwissProt.fasta
Posted date: May 9, 2024 7:34 AM
Number of letters in database: 32,416
Number of sequences in database: 10
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
