Comparative Genomics

ACIAD2841 / SwissProt Alignments

BLASTP 2.12.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: da9921e708671a65585756825ae894b3.SwissProt.fasta
           22 sequences; 9,811 total letters



Query= ACIAD2841

Length=314
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q6NE47 Putative lipid kinase MamU [Magnetospirillum gryphiswalden...  108     9e-31
Q2W8P4 Putative lipid kinase MamU [Magnetospirillum magneticum (s...  108     1e-30
Q2FWZ2 Diacylglycerol kinase [Staphylococcus aureus (strain NCTC ...  73.6    6e-18
Q2FFJ7 Diacylglycerol kinase [Staphylococcus aureus (strain USA300)]  73.6    6e-18
A6U302 Diacylglycerol kinase [Staphylococcus aureus (strain JH1)]     73.6    6e-18
A7X424 Diacylglycerol kinase [Staphylococcus aureus (strain Mu3 /...  73.6    6e-18
Q6GFF9 Diacylglycerol kinase [Staphylococcus aureus (strain MRSA2...  73.6    6e-18
Q8CRU5 Diacylglycerol kinase [Staphylococcus epidermidis (strain ...  70.9    5e-17
Q5HN36 Diacylglycerol kinase [Staphylococcus epidermidis (strain ...  70.9    5e-17
Q49YU2 Diacylglycerol kinase [Staphylococcus saprophyticus subsp....  70.5    7e-17
Q4L7L1 Diacylglycerol kinase [Staphylococcus haemolyticus (strain...  68.9    3e-16
B9DP10 Putative lipid kinase Sca_1050 [Staphylococcus carnosus (s...  67.8    6e-16
Q55452 Uncharacterized protein sll0036 [Synechocystis sp. (strain...  65.9    4e-15
O31502 Diacylglycerol kinase [Bacillus subtilis (strain 168)]         65.1    5e-15
B9DMT6 Diacylglycerol kinase [Staphylococcus carnosus (strain TM3...  64.7    6e-15
Q6GIR5 Putative lipid kinase SAR0780 [Staphylococcus aureus (stra...  63.5    2e-14
F1MAB7 Diacylglycerol kinase iota [Rattus norvegicus]                 50.1    8e-10
O75912 Diacylglycerol kinase iota [Homo sapiens]                      50.1    8e-10
D3YWQ0 Diacylglycerol kinase iota [Mus musculus]                      50.1    8e-10
P9WP28 Diacylglycerol kinase [Mycobacterium tuberculosis (strain ...  48.1    2e-09
P76407 Lipid kinase YegS [Escherichia coli (strain K12)]              46.6    6e-09
Q13574 Diacylglycerol kinase zeta [Homo sapiens]                      46.2    1e-08


>Q6NE47 Putative lipid kinase MamU [Magnetospirillum gryphiswaldense 
(strain DSM 6361 / JCM 21280 / NBRC 15271 / MSR-1)]
Length=297

 Score = 108 bits (271),  Expect = 9e-31
 Identities = 66/235 (28%), Positives = 118/235 (50%), Gaps = 1/235 (0%)

Query  72   IVAAGGDGTLNAVASRLVDTPIPMGILPLGTFNYVARVLNIPLDLLAAAEVIADGTIRSV  131
            I+  GGDG+L+     ++ +   +G+LPLGT NY+AR + +PLDL  AA  +A      +
Sbjct  63   IIIGGGDGSLSRALEHVLASGKSLGVLPLGTMNYMARQIGMPLDLAQAAVALAGAVQTPM  122

Query  132  HVATINDRIYLNNASLGLYPLFIQKREYYNKRFGRFPLNAYTSGLDVLIRDHKELKLSIS  191
             V  +NDR +L  A  G +P FIQ R+   ++ G F L    +GL  + R ++ ++  +S
Sbjct  123  DVGRVNDRYFLIRACFGAFPEFIQSRDRVRRKGGSF-LEGALAGLSGVARRYRIVEAELS  181

Query  192  VDDHVYPVKTPLIFFGNNQLQLKELNLHIAECAAQGRVAGVVVAKSDKLSLFKMLFELIK  251
                   + T  +   NN  +  +  L   E    G +   V   +  + L ++  +   
Sbjct  182  SPGGRARIATSFLMISNNLCRDSDPFLLERERMDGGSLGVYVGRSAGPVGLMELGLQAAM  241

Query  252  GRLEKAKDVYSFSADQVVVDCKRKKLTVAIDGEIEELQTPLTFAVKKNALNIMVP  306
            GR    + ++      + V  +++K  ++IDGE+E+++ P  F +   AL+I+VP
Sbjct  242  GRWASNEALFQGEMHWLEVQTEQRKPLISIDGEVEKMEGPFRFDILPGALSILVP  296


>Q2W8P4 Putative lipid kinase MamU [Magnetospirillum magneticum 
(strain AMB-1 / ATCC 700264)]
Length=297

 Score = 108 bits (270),  Expect = 1e-30
 Identities = 67/236 (28%), Positives = 116/236 (49%), Gaps = 3/236 (1%)

Query  72   IVAAGGDGTLNAVASRLVDTPIPMGILPLGTFNYVARVLNIPLDLLAAAEVIADGTIRSV  131
            ++  GGDG+L+     +V +   +G+LPLGT NYVAR   +P DL  AA  +AD      
Sbjct  63   VIIGGGDGSLSRSLKHVVGSGKSLGVLPLGTMNYVARQFGVPFDLDRAAVALADAVPTPT  122

Query  132  HVATINDRIYLNNASLGLYPLFIQKREYYNKRFGRFPLNAYTSGLDVLIRDHKELKLSIS  191
             +  +NDR +L  A LG +P FI+ R+   ++ G F L+   +GL  L R H+ ++  + 
Sbjct  123  DLGRVNDRFFLIRACLGAFPEFIRSRDEARRKGGSF-LDGALAGLTGLARGHRLIEAELI  181

Query  192  VDDHVYPVKTPLIFFGNNQLQLKELNLHIAECAAQGRVAGVVVAK-SDKLSLFKMLFELI  250
              D    + T      NN  +  +    +      G   GV + + +   SL  +  ++ 
Sbjct  182  GPDVQARIATSFFMVSNNMCRDSD-PFQLERERMDGATLGVYIGQGAGPFSLMDLGLQVA  240

Query  251  KGRLEKAKDVYSFSADQVVVDCKRKKLTVAIDGEIEELQTPLTFAVKKNALNIMVP  306
             GR    + +   S   + +  +++K  V+IDGE+E+++ P  F +    L ++VP
Sbjct  241  MGRWASNEALIRGSLPWLEIRTRQRKPLVSIDGEVEKMEAPFRFDILPGVLPMLVP  296


>Q2FWZ2 Diacylglycerol kinase [Staphylococcus aureus (strain NCTC 
8325 / PS 47)]
Length=315

 Score = 73.6 bits (179),  Expect = 6e-18
 Identities = 63/210 (30%), Positives = 98/210 (47%), Gaps = 16/210 (8%)

Query  1    MLKPLSIIYNGKSGFHASDKEGVYEQIMTLFTRYDFEIQVFELNEKITFDELMEQVLLRH  60
            M K   IIYN  SG     +E      +    +  +E   +   EKI  D  +E     H
Sbjct  1    MRKRARIIYNPTSGKELFKRE--LPDALIKLEKAGYETSAYA-TEKIG-DATLEAERAMH  56

Query  61   LNLNTSEYKGVIVAAGGDGTLNAVASRLVDTPI--PMGILPLGTFNYVARVLNIPLDLLA  118
             N +      V++AAGGDGTLN V + + + P    +G++P+GT N   R L+IP D++ 
Sbjct  57   ENYD------VLIAAGGDGTLNEVVNGIAEKPNRPKLGVIPMGTVNDFGRALHIPNDIMG  110

Query  119  AAEVIADGTIRSVHVATINDRIYLNNASLG-LYPLFIQKREYYNKRFGRFPLNAYTSGLD  177
            A +VI +G    V +  +N+R ++N A+ G L  +  +         G  P   Y  G +
Sbjct  111  ALDVIIEGHSTKVDIGKMNNRYFINLAAGGQLTQVSYETPSKLKSIVG--PFAYYIKGFE  168

Query  178  VLIRDHKELKLSISVDDHVYPVKTPLIFFG  207
            +L    K + L I  D +V+  +  L F G
Sbjct  169  ML-PQMKAVDLRIEYDGNVFQGEALLFFLG  197


>Q2FFJ7 Diacylglycerol kinase [Staphylococcus aureus (strain USA300)]
Length=315

 Score = 73.6 bits (179),  Expect = 6e-18
 Identities = 63/210 (30%), Positives = 98/210 (47%), Gaps = 16/210 (8%)

Query  1    MLKPLSIIYNGKSGFHASDKEGVYEQIMTLFTRYDFEIQVFELNEKITFDELMEQVLLRH  60
            M K   IIYN  SG     +E      +    +  +E   +   EKI  D  +E     H
Sbjct  1    MRKRARIIYNPTSGKELFKRE--LPDALIKLEKAGYETSAYA-TEKIG-DATLEAERAMH  56

Query  61   LNLNTSEYKGVIVAAGGDGTLNAVASRLVDTPI--PMGILPLGTFNYVARVLNIPLDLLA  118
             N +      V++AAGGDGTLN V + + + P    +G++P+GT N   R L+IP D++ 
Sbjct  57   ENYD------VLIAAGGDGTLNEVVNGIAEKPNRPKLGVIPMGTVNDFGRALHIPNDIMG  110

Query  119  AAEVIADGTIRSVHVATINDRIYLNNASLG-LYPLFIQKREYYNKRFGRFPLNAYTSGLD  177
            A +VI +G    V +  +N+R ++N A+ G L  +  +         G  P   Y  G +
Sbjct  111  ALDVIIEGHSTKVDIGKMNNRYFINLAAGGQLTQVSYETPSKLKSIVG--PFAYYIKGFE  168

Query  178  VLIRDHKELKLSISVDDHVYPVKTPLIFFG  207
            +L    K + L I  D +V+  +  L F G
Sbjct  169  ML-PQMKAVDLRIEYDGNVFQGEALLFFLG  197


>A6U302 Diacylglycerol kinase [Staphylococcus aureus (strain JH1)]
Length=315

 Score = 73.6 bits (179),  Expect = 6e-18
 Identities = 63/210 (30%), Positives = 98/210 (47%), Gaps = 16/210 (8%)

Query  1    MLKPLSIIYNGKSGFHASDKEGVYEQIMTLFTRYDFEIQVFELNEKITFDELMEQVLLRH  60
            M K   IIYN  SG     +E      +    +  +E   +   EKI  D  +E     H
Sbjct  1    MRKRARIIYNPTSGKELFKRE--LPDALIKLEKAGYETSAYA-TEKIG-DATLEAERAMH  56

Query  61   LNLNTSEYKGVIVAAGGDGTLNAVASRLVDTPI--PMGILPLGTFNYVARVLNIPLDLLA  118
             N +      V++AAGGDGTLN V + + + P    +G++P+GT N   R L+IP D++ 
Sbjct  57   ENYD------VLIAAGGDGTLNEVVNGIAEKPNRPKLGVIPMGTVNDFGRALHIPNDIMG  110

Query  119  AAEVIADGTIRSVHVATINDRIYLNNASLG-LYPLFIQKREYYNKRFGRFPLNAYTSGLD  177
            A +VI +G    V +  +N+R ++N A+ G L  +  +         G  P   Y  G +
Sbjct  111  ALDVIIEGHSTKVDIGKMNNRYFINLAAGGQLTQVSYETPSKLKSIVG--PFAYYIKGFE  168

Query  178  VLIRDHKELKLSISVDDHVYPVKTPLIFFG  207
            +L    K + L I  D +V+  +  L F G
Sbjct  169  ML-PQMKAVDLRIEYDGNVFQGEALLFFLG  197


>A7X424 Diacylglycerol kinase [Staphylococcus aureus (strain Mu3 
/ ATCC 700698)]
Length=315

 Score = 73.6 bits (179),  Expect = 6e-18
 Identities = 63/210 (30%), Positives = 98/210 (47%), Gaps = 16/210 (8%)

Query  1    MLKPLSIIYNGKSGFHASDKEGVYEQIMTLFTRYDFEIQVFELNEKITFDELMEQVLLRH  60
            M K   IIYN  SG     +E      +    +  +E   +   EKI  D  +E     H
Sbjct  1    MRKRARIIYNPTSGKELFKRE--LPDALIKLEKAGYETSAYA-TEKIG-DATLEAERAMH  56

Query  61   LNLNTSEYKGVIVAAGGDGTLNAVASRLVDTPI--PMGILPLGTFNYVARVLNIPLDLLA  118
             N +      V++AAGGDGTLN V + + + P    +G++P+GT N   R L+IP D++ 
Sbjct  57   ENYD------VLIAAGGDGTLNEVVNGIAEKPNRPKLGVIPMGTVNDFGRALHIPNDIMG  110

Query  119  AAEVIADGTIRSVHVATINDRIYLNNASLG-LYPLFIQKREYYNKRFGRFPLNAYTSGLD  177
            A +VI +G    V +  +N+R ++N A+ G L  +  +         G  P   Y  G +
Sbjct  111  ALDVIIEGHSTKVDIGKMNNRYFINLAAGGQLTQVSYETPSKLKSIVG--PFAYYIKGFE  168

Query  178  VLIRDHKELKLSISVDDHVYPVKTPLIFFG  207
            +L    K + L I  D +V+  +  L F G
Sbjct  169  ML-PQMKAVDLRIEYDGNVFQGEALLFFLG  197


>Q6GFF9 Diacylglycerol kinase [Staphylococcus aureus (strain MRSA252)]
Length=315

 Score = 73.6 bits (179),  Expect = 6e-18
 Identities = 63/210 (30%), Positives = 98/210 (47%), Gaps = 16/210 (8%)

Query  1    MLKPLSIIYNGKSGFHASDKEGVYEQIMTLFTRYDFEIQVFELNEKITFDELMEQVLLRH  60
            M K   IIYN  SG     +E      +    +  +E   +   EKI  D  +E     H
Sbjct  1    MRKRARIIYNPTSGKEQFKRE--LPDALIKLEKAGYETSAYA-TEKIG-DATLEAERAMH  56

Query  61   LNLNTSEYKGVIVAAGGDGTLNAVASRLVDTPI--PMGILPLGTFNYVARVLNIPLDLLA  118
             N +      V++AAGGDGTLN V + + + P    +G++P+GT N   R L+IP D++ 
Sbjct  57   ENYD------VLIAAGGDGTLNEVVNGIAEKPNRPKLGVIPMGTVNDFGRALHIPNDIMG  110

Query  119  AAEVIADGTIRSVHVATINDRIYLNNASLG-LYPLFIQKREYYNKRFGRFPLNAYTSGLD  177
            A +VI +G    V +  +N+R ++N A+ G L  +  +         G  P   Y  G +
Sbjct  111  ALDVIIEGHSTKVDIGKMNNRYFINLAAGGQLTQVSYETPSKLKSIVG--PFAYYIKGFE  168

Query  178  VLIRDHKELKLSISVDDHVYPVKTPLIFFG  207
            +L    K + L I  D +V+  +  L F G
Sbjct  169  ML-PQMKAVDLRIEYDGNVFQGEALLFFLG  197


>Q8CRU5 Diacylglycerol kinase [Staphylococcus epidermidis (strain 
ATCC 12228 / FDA PCI 1200)]
Length=316

 Score = 70.9 bits (172),  Expect = 5e-17
 Identities = 46/145 (32%), Positives = 77/145 (53%), Gaps = 7/145 (5%)

Query  66   SEYKGVIVAAGGDGTLNAVASRLVDTPI--PMGILPLGTFNYVARVLNIPLDLLAAAEVI  123
            SEY  +++AAGGDGTLN V + + + P    +G++P+GT N   R L++P D++ A +VI
Sbjct  57   SEYD-LLIAAGGDGTLNEVVNGIAEQPNRPKLGVIPMGTVNDFGRALHLPSDIMGAIDVI  115

Query  124  ADGTIRSVHVATINDRIYLNNASLG-LYPLFIQKREYYNKRFGRFPLNAYTSGLDVLIRD  182
             DG    V +  +N+R ++N A+ G L  +  +         G  P   Y  G ++L   
Sbjct  116  IDGHTTKVDIGKMNNRYFINLAAGGKLTQVSYETPSKLKSIVG--PFAYYIKGFEML-PQ  172

Query  183  HKELKLSISVDDHVYPVKTPLIFFG  207
             K + + I  DD+++  +  L   G
Sbjct  173  MKAVDVRIEYDDNIFQGEALLFLLG  197


>Q5HN36 Diacylglycerol kinase [Staphylococcus epidermidis (strain 
ATCC 35984 / RP62A)]
Length=316

 Score = 70.9 bits (172),  Expect = 5e-17
 Identities = 46/145 (32%), Positives = 77/145 (53%), Gaps = 7/145 (5%)

Query  66   SEYKGVIVAAGGDGTLNAVASRLVDTPI--PMGILPLGTFNYVARVLNIPLDLLAAAEVI  123
            SEY  +++AAGGDGTLN V + + + P    +G++P+GT N   R L++P D++ A +VI
Sbjct  57   SEYD-LLIAAGGDGTLNEVVNGIAEQPNRPKLGVIPMGTVNDFGRALHLPSDIMGAIDVI  115

Query  124  ADGTIRSVHVATINDRIYLNNASLG-LYPLFIQKREYYNKRFGRFPLNAYTSGLDVLIRD  182
             DG    V +  +N+R ++N A+ G L  +  +         G  P   Y  G ++L   
Sbjct  116  IDGHTTKVDIGKMNNRYFINLAAGGKLTQVSYETPSKLKSIVG--PFAYYIKGFEML-PQ  172

Query  183  HKELKLSISVDDHVYPVKTPLIFFG  207
             K + + I  DD+++  +  L   G
Sbjct  173  MKAVDVRIEYDDNIFQGEALLFLLG  197


>Q49YU2 Diacylglycerol kinase [Staphylococcus saprophyticus subsp. 
saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 
/ NCTC 7292 / S-41)]
Length=305

 Score = 70.5 bits (171),  Expect = 7e-17
 Identities = 45/140 (32%), Positives = 74/140 (53%), Gaps = 6/140 (4%)

Query  71   VIVAAGGDGTLNAVASRLVDTPI--PMGILPLGTFNYVARVLNIPLDLLAAAEVIADGTI  128
            V++AAGGDGTLN V + + + P    +GI+P+GT N   R L++P D+++A +VI +G +
Sbjct  61   VLIAAGGDGTLNEVINGIAEKPNRPSLGIIPMGTVNDFGRALHLPTDIMSAIDVIIEGHM  120

Query  129  RSVHVATINDRIYLNNASLG-LYPLFIQKREYYNKRFGRFPLNAYTSGLDVLIRDHKELK  187
              V +  +N R ++N A+ G L  +  +         G  P   Y  G ++L    K + 
Sbjct  121  TRVDIGKMNSRYFINLAAGGQLTQVSYETPSKLKSIVG--PFAYYIKGFEML-PQMKAVD  177

Query  188  LSISVDDHVYPVKTPLIFFG  207
            + I  DD V+  +  L   G
Sbjct  178  IRIEYDDEVFQGEALLFLLG  197


>Q4L7L1 Diacylglycerol kinase [Staphylococcus haemolyticus (strain 
JCSC1435)]
Length=330

 Score = 68.9 bits (167),  Expect = 3e-16
 Identities = 58/210 (28%), Positives = 93/210 (44%), Gaps = 16/210 (8%)

Query  1    MLKPLSIIYNGKSGFHASDKEGVYEQIMTLFTRYDFEIQVFELNEKITFDELMEQVLLRH  60
            M K   IIYN  SG     +      ++    R  +E   +    +       E+ L R 
Sbjct  1    MRKCARIIYNPTSGKELFKR--TLPDVLIKLERAGYETSAYATEREGDATLEAERALKRD  58

Query  61   LNLNTSEYKGVIVAAGGDGTLNAVASRLVDTPI--PMGILPLGTFNYVARVLNIPLDLLA  118
             +        +I+AAGGDGTLN V + + + P    +GI+P+GT N   R L++P D++ 
Sbjct  59   YD--------IIIAAGGDGTLNEVVNGIAEQPNRPKLGIIPMGTVNDFGRALHLPSDIMG  110

Query  119  AAEVIADGTIRSVHVATINDRIYLNNASLG-LYPLFIQKREYYNKRFGRFPLNAYTSGLD  177
            A +VI D     V +  +N+R ++N A+ G L  +  +         G  P   Y  G +
Sbjct  111  AVDVIIDDHTTKVDIGKMNNRYFINLAAGGQLTQVSYETPSRLKSIVG--PFAYYIKGFE  168

Query  178  VLIRDHKELKLSISVDDHVYPVKTPLIFFG  207
            +L    K + L I  D+ V+  +  L   G
Sbjct  169  ML-PQMKAVDLRIEYDNQVFQGEALLFLLG  197


>B9DP10 Putative lipid kinase Sca_1050 [Staphylococcus carnosus 
(strain TM300)]
Length=306

 Score = 67.8 bits (164),  Expect = 6e-16
 Identities = 63/246 (26%), Positives = 118/246 (48%), Gaps = 25/246 (10%)

Query  71   VIVAAGGDGTLNAVASRLV--DTPIPMGILPLGTFNYVARVLNIPLDLLAAAEVIADGTI  128
            V    GGDGT+N + + +   +  IP+GI+P GTFN   + LN+     AAA  + +  I
Sbjct  68   VFFVLGGDGTVNELVNGVARNNLEIPIGIIPGGTFNDFTKTLNLSPRTAAAANELLNSKI  127

Query  129  RSVHVATINDRIYLNNASLGLYPLFIQKREYYNKR-FGRFPLNAYTSGLDVLIRDHKELK  187
            +S  V  +ND   LN A +G+     +  +   KR  G+F   +Y      +I + K  +
Sbjct  128  KSFDVLKVNDTYALNFAGIGMMVQNSENVDANKKRILGKF---SYVFTTLKVIANPKIYQ  184

Query  188  LSISVDDHVYPVKTPLI------FFGNNQLQLKELNLHIAECAAQGRVAGVVVAKSDKLS  241
             +I  ++  Y  +T +I      + G +++ L++L+    E         + V K+  +S
Sbjct  185  YTIKANNEEYSGETSMILIANGNYVGGSKIPLEDLSPSDGE-------MNIFVFKNHNMS  237

Query  242  LFKMLFELIKGRL---EKAKDVYSFSADQVVVDCKRKKLTVAIDGEIEELQTPLTFAVKK  298
            L K  F+ +K  L   +  +++   + D++ ++  R    + IDGEI    TP+   + K
Sbjct  238  LIKDFFQ-VKDSLRWNDITENIRLITTDEMKLE-TRPSTKIDIDGEI-MFDTPVDIKLLK  294

Query  299  NALNIM  304
            + + ++
Sbjct  295  DKVKLL  300


>Q55452 Uncharacterized protein sll0036 [Synechocystis sp. (strain 
PCC 6803 / Kazusa)]
Length=433

 Score = 65.9 bits (159),  Expect = 4e-15
 Identities = 70/280 (25%), Positives = 115/280 (41%), Gaps = 19/280 (7%)

Query  42   ELNEKITFD-------ELMEQVLLRHLNLNTS---EYKGVIVAAGGDGTLNAVASRLVDT  91
            E+N KITF        +  ++++ R    N     E    I+A+GGDGT++ VA+ LV+T
Sbjct  154  EINLKITFTSAEVNVTDQAKEIVKRIKQANEQSDGEGDSFIIASGGDGTVSGVAAALVNT  213

Query  92   PIPMGILPLGTFNYVARVLNIPLDLLAAAEVIADGTIRSVHVATINDRIYLNNASLGLYP  151
             IP+GI+P GT N  +  L IP  +  A + I  G  + V  A  ND   L  A +G   
Sbjct  214  GIPLGIIPRGTANAFSVALGIPTQIPGACQTINRGITKVVDTALCNDIPMLLLAGVGFEA  273

Query  152  LFIQKREYYNKRFGRFPLNAYTSGLDVLIRDHKELKLSISVDDHVYPVKTPLIFFGNNQL  211
              ++K +   K      + AY        R+ +  +  I +D     ++   I   N   
Sbjct  274  EMVEKADRELK--NNLGVMAYIFAGIQQAREQELFEAHIEIDSETTTMEASAITIANAAP  331

Query  212  QLKELNLHIAECAAQGRVAGVVVAKSD-KLSLFKMLFELIKGRLEK----AKDVYSFSAD  266
                      + +    +  + VA S   L   +++  L    L K     ++V     +
Sbjct  332  PTSVFAQGAGQVSFTDGLLDITVASSQTALQGLQVVTNLFTSALSKNPSDNENVLHLYGE  391

Query  267  QVVVDCKRKKLTVAIDGEIEELQTPLTFAVKKNALNIMVP  306
             + V     +  + +DGEI    TP+       +LNI  P
Sbjct  392  SIKVTTSPPQ-KIVVDGEIIG-TTPVEVKCLPKSLNIFAP  429


>O31502 Diacylglycerol kinase [Bacillus subtilis (strain 168)]
Length=303

 Score = 65.1 bits (157),  Expect = 5e-15
 Identities = 46/150 (31%), Positives = 72/150 (48%), Gaps = 13/150 (9%)

Query  2    LKPLSIIYNGKSGFHASDKEGVYEQIMTLFTRYDFEIQVFELNEKITFDELMEQVLLRHL  61
            +K   IIYN  SG     K     Q++  F +  +E                ++  LR  
Sbjct  1    MKRARIIYNPTSGREIFKKH--LAQVLQKFEQAGYETSTHATTCAGDATHAAKEAALREF  58

Query  62   NLNTSEYKGVIVAAGGDGTLNAVASRL--VDTPIPMGILPLGTFNYVARVLNIPL-DLLA  118
            +L        I+AAGGDGT+N V + L  +D    +G++P+GT N  AR L IP  D+L 
Sbjct  59   DL--------IIAAGGDGTINEVVNGLAPLDNRPTLGVIPVGTTNDFARALGIPREDILK  110

Query  119  AAEVIADGTIRSVHVATINDRIYLNNASLG  148
            AA+ + +G  R + +  +N + ++N A  G
Sbjct  111  AADTVINGVARPIDIGQVNGQYFINIAGGG  140


>B9DMT6 Diacylglycerol kinase [Staphylococcus carnosus (strain 
TM300)]
Length=306

 Score = 64.7 bits (156),  Expect = 6e-15
 Identities = 60/241 (25%), Positives = 103/241 (43%), Gaps = 6/241 (2%)

Query  71   VIVAAGGDGTLNAVASRLVDTPI--PMGILPLGTFNYVARVLNIPLDLLAAAEVIADGTI  128
            +++ AGGDGTLN V + + + P    +G++P+GT N   R L++P D+L A +VI +G  
Sbjct  61   MLIVAGGDGTLNEVVNGIAEHPKRPKIGVIPMGTVNDFGRALHLPTDILKAVDVIIEGHS  120

Query  129  RSVHVATINDRIYLNNASLGLYPLFIQKREYYNKRFGRFPLNAYTSGLDVLIRDHKELKL  188
              V +  +N R ++N A+ G       +     K F   P   Y  G+++L      + +
Sbjct  121  VKVDIGKMNSRYFINLAAGGRITEVSYETSSKLKTFVG-PFAYYIKGMEML-PQMTNVDV  178

Query  189  SISVDDHVYPVKTPLIFFGNNQLQLKELNLHIAECAAQGRVAGVVVAKSDKLSLFKMLFE  248
             I  D  V+  +  L   G          L        G    ++V K++   L  ++  
Sbjct  179  RIEYDGQVFQGEILLFLLGLTNSMAGFEKLVPDARLDDGYFTLIIVQKANLAELGHIMTL  238

Query  249  LIKGRLEKAKDVYSFSADQVVVDCKRKKLTVAIDGEIEELQTPLTFAVKKNALNIMVPAH  308
              +G   K   V    A  V +    +++ + +DGE    Q P  F   K  + +  P  
Sbjct  239  ASRGEHIKHPKVIYEKAKSVNIS-SFEQMPLNVDGEYGG-QLPANFLNLKQHIEVYTPKD  296

Query  309  V  309
            V
Sbjct  297  V  297


>Q6GIR5 Putative lipid kinase SAR0780 [Staphylococcus aureus (strain 
MRSA252)]
Length=305

 Score = 63.5 bits (153),  Expect = 2e-14
 Identities = 66/279 (24%), Positives = 119/279 (43%), Gaps = 44/279 (16%)

Query  57   LLRHLNLNTSEYKGVIVA-------------------AGGDGTLNAVASRLV--DTPIPM  95
            + +HL++  SE +G I+                     GGDGT+N + + ++  D  +P+
Sbjct  35   ICKHLSIQLSENEGDIIKYCQEIKAKDYAKDVDILFILGGDGTVNELINGVMTHDLQLPI  94

Query  96   GILPLGTFNYVARVLNIPLDLLAAAEVIADGTIRSVHVATINDRIYLNNASLGLYPLFIQ  155
            GILP GTFN   + LNI  +   A+E +    + +  V  IN++  LN   LGL     +
Sbjct  95   GILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYALNFVGLGLIVQNAE  154

Query  156  KREYYNKR-FGRFPLNAYTSGLDVLIRDHKELKLSISVDDHVYPVKTPLIFFGNNQLQLK  214
              +  +K  FG+    +Y       + +  +    +S+DD  Y  +T +I   N    + 
Sbjct  155  NVQDGSKDIFGKL---SYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILSANGPF-IG  210

Query  215  ELNLHIAECAAQGRVAGVVVAKSDKLSLFKMLFELIKGRLEKAKDVYSFS-ADQVVVDCK  273
               + + + + Q       +      S+   +F        K +D  +++   Q +    
Sbjct  211  GSRIPLTDLSPQDGELNTFIFNEQSFSILNDIF--------KKRDSMNWNEITQGIEHIP  262

Query  274  RKKLT--------VAIDGEIEELQTPLTFAVKKNALNIM  304
             KK++        V IDGEI  L+TP+   V  NA+ ++
Sbjct  263  GKKISLTTDPTMKVDIDGEI-SLETPIDIEVIPNAIQLL  300


>F1MAB7 Diacylglycerol kinase iota [Rattus norvegicus]
Length=1050

 Score = 50.1 bits (118),  Expect = 8e-10
 Identities = 39/115 (34%), Positives = 61/115 (53%), Gaps = 19/115 (17%)

Query  1    MLKPLSIIYNGKSGFHASDKEGVYEQIMTLFTRYDFEIQVFELNEKITFDELMEQVLLRH  60
            ++KPL +  N KSG +   K      ++ +F  Y    QVF+L+++   D L  ++  + 
Sbjct  368  LMKPLLVFVNPKSGGNQGTK------VLQMFMWYLNPRQVFDLSQEGPKDAL--ELYRKV  419

Query  61   LNLNTSEYKGVIVAAGGDGTLNAVASRLVDTPI----PMGILPLGTFNYVARVLN  111
             NL        I+A GGDGT+  + S L +  +    P+G+LPLGT N +AR LN
Sbjct  420  PNLR-------ILACGGDGTVGWILSILDELQLSPQPPVGVLPLGTGNDLARTLN  467


>O75912 Diacylglycerol kinase iota [Homo sapiens]
Length=1065

 Score = 50.1 bits (118),  Expect = 8e-10
 Identities = 39/115 (34%), Positives = 61/115 (53%), Gaps = 19/115 (17%)

Query  1    MLKPLSIIYNGKSGFHASDKEGVYEQIMTLFTRYDFEIQVFELNEKITFDELMEQVLLRH  60
            ++KPL +  N KSG +   K      ++ +F  Y    QVF+L+++   D L  ++  + 
Sbjct  373  LMKPLLVFVNPKSGGNQGTK------VLQMFMWYLNPRQVFDLSQEGPKDAL--ELYRKV  424

Query  61   LNLNTSEYKGVIVAAGGDGTLNAVASRLVDTPI----PMGILPLGTFNYVARVLN  111
             NL        I+A GGDGT+  + S L +  +    P+G+LPLGT N +AR LN
Sbjct  425  PNLR-------ILACGGDGTVGWILSILDELQLSPQPPVGVLPLGTGNDLARTLN  472


>D3YWQ0 Diacylglycerol kinase iota [Mus musculus]
Length=1071

 Score = 50.1 bits (118),  Expect = 8e-10
 Identities = 39/115 (34%), Positives = 61/115 (53%), Gaps = 19/115 (17%)

Query  1    MLKPLSIIYNGKSGFHASDKEGVYEQIMTLFTRYDFEIQVFELNEKITFDELMEQVLLRH  60
            ++KPL +  N KSG +   K      ++ +F  Y    QVF+L+++   D L  ++  + 
Sbjct  368  LMKPLLVFVNPKSGGNQGTK------VLQMFMWYLNPRQVFDLSQEGPKDAL--EMYRKV  419

Query  61   LNLNTSEYKGVIVAAGGDGTLNAVASRLVDTPI----PMGILPLGTFNYVARVLN  111
             NL        I+A GGDGT+  + S L +  +    P+G+LPLGT N +AR LN
Sbjct  420  PNLR-------ILACGGDGTVGWILSILDELQLSPQPPVGVLPLGTGNDLARTLN  467


>P9WP28 Diacylglycerol kinase [Mycobacterium tuberculosis (strain 
CDC 1551 / Oshkosh)]
Length=309

 Score = 48.1 bits (113),  Expect = 2e-09
 Identities = 30/83 (36%), Positives = 45/83 (54%), Gaps = 4/83 (5%)

Query  59   RHLNLNTSEYKGV--IVAAGGDGTLNAVASRLVDTPIPMGILPLGTFNYVARVLNIPL-D  115
            RHL L  +  KG   ++  GGDG ++     L  T IP+GI+P GT N  AR   +P  +
Sbjct  57   RHL-LAAAVAKGTDAVMVTGGDGVVSNALQVLAGTDIPLGIIPAGTGNDHAREFGLPTKN  115

Query  116  LLAAAEVIADGTIRSVHVATIND  138
              AAA+++ DG   ++ +  I D
Sbjct  116  PKAAADIVVDGWTETIDLGRIQD  138


>P76407 Lipid kinase YegS [Escherichia coli (strain K12)]
Length=299

 Score = 46.6 bits (109),  Expect = 6e-09
 Identities = 29/81 (36%), Positives = 45/81 (56%), Gaps = 4/81 (5%)

Query  72   IVAAGGDGTLNAVASRLVDTP---IP-MGILPLGTFNYVARVLNIPLDLLAAAEVIADGT  127
            ++A GGDGT+N V++ L+      IP +GILPLGT N  A  + IP  L  A ++   G 
Sbjct  61   VIAGGGDGTINEVSTALIQCEGDDIPALGILPLGTANDFATSVGIPEALDKALKLAIAGD  120

Query  128  IRSVHVATINDRIYLNNASLG  148
              ++ +A +N +    N + G
Sbjct  121  AIAIDMAQVNKQTCFINMATG  141


>Q13574 Diacylglycerol kinase zeta [Homo sapiens]
Length=928

 Score = 46.2 bits (108),  Expect = 1e-08
 Identities = 39/115 (34%), Positives = 56/115 (49%), Gaps = 19/115 (17%)

Query  1    MLKPLSIIYNGKSGFHASDKEGVYEQIMTLFTRYDFEIQVFELNEKITFDELMEQVLLRH  60
            ++KPL +  N KSG +   K      I+  F  Y    QVF+L++    + L     + +
Sbjct  292  LMKPLLVFVNPKSGGNQGAK------IIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHN  345

Query  61   LNLNTSEYKGVIVAAGGDGTLNAVASRL----VDTPIPMGILPLGTFNYVARVLN  111
            L          I+A GGDGT+  + S L    +  P P+ ILPLGT N +AR LN
Sbjct  346  LR---------ILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLN  391



Lambda      K        H        a         alpha
   0.324    0.140    0.396    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 2285207


  Database: da9921e708671a65585756825ae894b3.SwissProt.fasta
    Posted date:  May 9, 2024  12:04 AM
  Number of letters in database: 9,811
  Number of sequences in database:  22



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40