BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 0e99ec8e4b33b2e93b4544f429c87e63.SwissProt.fasta
19 sequences; 5,781 total letters
Query= ACIAD2948
Length=269
Score E
Sequences producing significant alignments: (Bits) Value
Q9Y140 Dehydrogenase/reductase SDR family protein 7-like [Drosoph... 184 7e-60
Q7Q732 Dehydrogenase/reductase SDR family protein 7-like [Anophel... 178 7e-58
Q566S6 Dehydrogenase/reductase SDR family member 7B [Danio rerio] 172 9e-56
Q0IH28 Dehydrogenase/reductase SDR family member 7B [Xenopus laevis] 167 1e-53
Q0VFE7 Dehydrogenase/reductase SDR family member 7B [Xenopus trop... 165 6e-53
Q99J47 Dehydrogenase/reductase SDR family member 7B [Mus musculus] 162 1e-51
Q3T0R4 Dehydrogenase/reductase SDR family member 7B [Bos taurus] 162 1e-51
Q5RJY4 Dehydrogenase/reductase SDR family member 7B [Rattus norve... 161 4e-51
Q6IAN0 Dehydrogenase/reductase SDR family member 7B [Homo sapiens] 160 1e-50
Q5R6U1 Dehydrogenase/reductase SDR family member 7B [Pongo abelii] 159 2e-50
Q9Y394 Dehydrogenase/reductase SDR family member 7 [Homo sapiens] 145 7e-45
A6SSW9 Oxidoreductase BOA17 [Botryotinia fuckeliana (strain B05.10)] 117 8e-35
Q8CHS7 Dehydrogenase/reductase SDR family member 7C [Mus musculus] 116 3e-34
D3ZGP9 Dehydrogenase/reductase SDR family member 7C [Rattus norve... 115 9e-34
P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG [Escherich... 107 2e-31
Q8A945 3-ketodihydrosphingosine reductase [Bacteroides thetaiotao... 107 3e-31
P37694 Ketoacyl reductase HetN [Nostoc sp. (strain PCC 7120 / SAG... 108 3e-31
Q6F7B8 Fatty acyl-CoA reductase [Acinetobacter baylyi (strain ATC... 108 4e-31
P0A2C9 3-oxoacyl-[acyl-carrier-protein] reductase FabG [Salmonell... 106 5e-31
>Q9Y140 Dehydrogenase/reductase SDR family protein 7-like [Drosophila
melanogaster]
Length=326
Score = 184 bits (466), Expect = 7e-60
Identities = 101/269 (38%), Positives = 157/269 (58%), Gaps = 5/269 (2%)
Query 5 NSLENKVVWITGASSGLGKALARECALQGAQVVLTARRYDELEKVRFGLFKPEQHAS--- 61
N L KVV ITGASSGLG++LA G +V+L ARR ELE+V+ L + +
Sbjct 49 NQLPGKVVLITGASSGLGESLAHVFYRAGCRVILAARRTQELERVKKDLLALDVDPAYPP 108
Query 62 --VAADITDETQVRHAYEQVLAKKGRIDWLINNAGLSQRALIQDTTMQTERAIMEIDYFS 119
+ D+ + + +VLA ++D LINN G+S RA + T + + +M ++YF
Sbjct 109 TVLPLDLAELNSIPEFVTRVLAVYNQVDILINNGGISVRADVASTAVDVDLKVMVVNYFG 168
Query 120 QVFLTKTVLPTFIEQKSGRIAYVSSVAGLLGTQYRASYSAAKAAIHMWANSLRAEVAEFG 179
V LTK +LP+ +++ SG I ++SSV G RA+YSA+K A+ +A+SLRAEVA
Sbjct 169 SVALTKALLPSMVKRGSGHICFISSVQGKFAIPQRAAYSASKHAMQAFADSLRAEVANKN 228
Query 180 IDVSVIFPGFVKTNVSFNALNGEGKPQGHQDEAIENGLEADVFAEEVVKALMNEEEYIVV 239
I+VS + PG+++T +S NAL G G G DE G+ D AE +++ ++ +E I+V
Sbjct 229 INVSCVSPGYIRTQLSLNALTGSGSSYGKVDETTAKGMSPDKLAERILQCILRKEPDIIV 288
Query 240 GGAKEKLGVWISRLSPALLYKMIRKMKVK 268
+ K+ ++ L P+L + ++ K VK
Sbjct 289 SDVQAKIAYYLRHLCPSLYFWIMAKRAVK 317
>Q7Q732 Dehydrogenase/reductase SDR family protein 7-like [Anopheles
gambiae]
Length=317
Score = 178 bits (452), Expect = 7e-58
Identities = 105/270 (39%), Positives = 153/270 (57%), Gaps = 10/270 (4%)
Query 7 LENKVVWITGASSGLGKALARECALQGAQVVLTARRYDELEKVRFGLFKPEQHASVAA-- 64
L KVV ITGASSGLG+ALA L G +VVL ARR DELE+VR L E HA+V
Sbjct 46 LNGKVVLITGASSGLGEALAHSFFLAGCKVVLAARRKDELERVRKDLL--ELHATVPTHP 103
Query 65 ------DITDETQVRHAYEQVLAKKGRIDWLINNAGLSQRALIQDTTMQTERAIMEIDYF 118
D++D + + VL G ID L+NN G+S R T + + IM ++YF
Sbjct 104 PIILPLDLSDLNSIGGKVQSVLEIHGAIDILVNNGGISVRGDALSTAIDVDIRIMLVNYF 163
Query 119 SQVFLTKTVLPTFIEQKSGRIAYVSSVAGLLGTQYRASYSAAKAAIHMWANSLRAEVAEF 178
V LTK LP+ + +K GRI +SSV G +R++YSA+K A+ + +SLRAEVA+
Sbjct 164 GSVALTKACLPSMMARKEGRIVSISSVQGKFAIPHRSAYSASKHAMQAFCDSLRAEVAKD 223
Query 179 GIDVSVIFPGFVKTNVSFNALNGEGKPQGHQDEAIENGLEADVFAEEVVKALMNEEEYIV 238
I V++I PG++ T +S NAL G G G D A G A ++KA+ +E+ ++
Sbjct 224 NIKVTLISPGYINTALSLNALTGTGASYGKMDAATAGGASPQDTASSILKAIARDEKDVM 283
Query 239 VGGAKEKLGVWISRLSPALLYKMIRKMKVK 268
+ + W+ L+P++ + +++K K
Sbjct 284 LAPIAPRAAYWLRHLAPSVYFWIMKKRAEK 313
>Q566S6 Dehydrogenase/reductase SDR family member 7B [Danio rerio]
Length=309
Score = 172 bits (437), Expect = 9e-56
Identities = 94/264 (36%), Positives = 158/264 (60%), Gaps = 7/264 (3%)
Query 6 SLENKVVWITGASSGLGKALARECALQGAQVVLTARRYDELEKV-------RFGLFKPEQ 58
++++KVV ITGASSGLGK AR GA+++L R L++V +G K
Sbjct 34 NIQDKVVVITGASSGLGKECARVFHAAGARLILCGRDQRRLQEVVEELGNKTYGKTKTYT 93
Query 59 HASVAADITDETQVRHAYEQVLAKKGRIDWLINNAGLSQRALIQDTTMQTERAIMEIDYF 118
+V D+++ + V A ++L + G +D LIN AG+S R I DT + +R +ME +YF
Sbjct 94 PCTVTFDLSNTSVVCSAAAEILKRHGHVDVLINIAGVSYRGNILDTHVSVQREVMETNYF 153
Query 119 SQVFLTKTVLPTFIEQKSGRIAYVSSVAGLLGTQYRASYSAAKAAIHMWANSLRAEVAEF 178
V LT+ +LP+ +++ SG I +SSV G + YR++Y+A+K A+ + + LRAEV
Sbjct 154 GPVALTQAILPSMVDRGSGHIVVISSVQGKISIPYRSAYAASKHAMQAYYDCLRAEVDSL 213
Query 179 GIDVSVIFPGFVKTNVSFNALNGEGKPQGHQDEAIENGLEADVFAEEVVKALMNEEEYIV 238
G+ VSV+ PG+V+TN+S NA+ G+G G D G + A++++KA+ +++ +V
Sbjct 214 GLHVSVLSPGYVRTNMSINAVTGDGSKYGVMDRTTATGADPVDVAKDILKAVCQKKKDVV 273
Query 239 VGGAKEKLGVWISRLSPALLYKMI 262
+ G +++ L PAL ++++
Sbjct 274 MAGLGPTTAIYLRTLWPALYFRVM 297
>Q0IH28 Dehydrogenase/reductase SDR family member 7B [Xenopus
laevis]
Length=323
Score = 167 bits (424), Expect = 1e-53
Identities = 96/272 (35%), Positives = 157/272 (58%), Gaps = 10/272 (4%)
Query 1 MSKLNS---LENKVVWITGASSGLGKALARECALQGAQVVLTARRYD-------ELEKVR 50
+ KL S L+ VV ITGA+SGLGK A+ G+ +VL R + EL +R
Sbjct 25 LQKLRSGAYLQAAVVVITGATSGLGKECAKVFYAAGSHLVLCGRDEERLKDLVQELNNMR 84
Query 51 FGLFKPEQHASVAADITDETQVRHAYEQVLAKKGRIDWLINNAGLSQRALIQDTTMQTER 110
+ + V D++D V A +++L GR+D LINNAG+S R I DT + +R
Sbjct 85 LKSTQLHKPHMVIFDLSDVEAVNTAAKEILHLAGRVDILINNAGISYRGTILDTKVSVDR 144
Query 111 AIMEIDYFSQVFLTKTVLPTFIEQKSGRIAYVSSVAGLLGTQYRASYSAAKAAIHMWANS 170
+M+ +YF V LTK +LP+ I+ + G + +SSV G + +R++YSA+K A + +
Sbjct 145 MVMDTNYFGPVALTKALLPSMIKNRRGHVVVISSVQGKISIPFRSAYSASKHATQAFFDC 204
Query 171 LRAEVAEFGIDVSVIFPGFVKTNVSFNALNGEGKPQGHQDEAIENGLEADVFAEEVVKAL 230
LRAE++ + IDV+V+ PG++KTN+S NA+ G+G G D+ +G + A+ V++A+
Sbjct 205 LRAEMSPYDIDVTVVNPGYIKTNLSLNAVTGDGSGYGVMDKNTADGRTPEEVAQTVLRAV 264
Query 231 MNEEEYIVVGGAKEKLGVWISRLSPALLYKMI 262
+ ++V G L V++ L+P L + ++
Sbjct 265 GERRKELLVAGLVPTLAVYLRTLAPTLFFSIM 296
>Q0VFE7 Dehydrogenase/reductase SDR family member 7B [Xenopus
tropicalis]
Length=309
Score = 165 bits (418), Expect = 6e-53
Identities = 91/263 (35%), Positives = 151/263 (57%), Gaps = 7/263 (3%)
Query 7 LENKVVWITGASSGLGKALARECALQGAQVVLTARRYD-------ELEKVRFGLFKPEQH 59
L++ VV ITGA+SGLG+ A+ G ++VL R + EL ++R + +
Sbjct 34 LQDAVVVITGATSGLGRECAKVFYAAGTRLVLCGRSEEGLKNLVQELSQMRIKSAQLHKP 93
Query 60 ASVAADITDETQVRHAYEQVLAKKGRIDWLINNAGLSQRALIQDTTMQTERAIMEIDYFS 119
V D++D V A ++L GR+D LINNAG+S R I DT + +R +M+ +YF
Sbjct 94 HMVIFDLSDVEAVNSAANEILHLTGRVDILINNAGISYRGTILDTKVSVDRMVMDTNYFG 153
Query 120 QVFLTKTVLPTFIEQKSGRIAYVSSVAGLLGTQYRASYSAAKAAIHMWANSLRAEVAEFG 179
V LTK ++P+ I+ + G I +SSV G + +R++YSA+K A + + LRAE++ +
Sbjct 154 PVALTKALIPSMIKNRRGHIVVISSVQGKISIPFRSAYSASKHATQAFFDCLRAEMSPYE 213
Query 180 IDVSVIFPGFVKTNVSFNALNGEGKPQGHQDEAIENGLEADVFAEEVVKALMNEEEYIVV 239
IDV+V+ PG++KTN+S NA+ G+G G D G + A+ V++A+ + ++V
Sbjct 214 IDVTVVNPGYIKTNLSLNAVTGDGSNYGVMDNNTAEGRTPEEVAQTVLRAVGERRKELLV 273
Query 240 GGAKEKLGVWISRLSPALLYKMI 262
G L V++ L+P + + +
Sbjct 274 AGLVPTLAVYLRTLAPTIFFSFM 296
>Q99J47 Dehydrogenase/reductase SDR family member 7B [Mus musculus]
Length=323
Score = 162 bits (410), Expect = 1e-51
Identities = 93/261 (36%), Positives = 149/261 (57%), Gaps = 5/261 (2%)
Query 7 LENKVVWITGASSGLGKALARECALQGAQVVLTARRYDELEKVRFGLFKPEQHAS----- 61
L N VV +TGA+SGLG+ A+ GA++VL R LE++ L Q +
Sbjct 50 LRNAVVVVTGATSGLGRECAKVFHAAGAKLVLCGRNVKALEELSRELAGSSQGQTHQPFV 109
Query 62 VAADITDETQVRHAYEQVLAKKGRIDWLINNAGLSQRALIQDTTMQTERAIMEIDYFSQV 121
V D+ D + A ++L G +D LINNAG+S R I DT + +R +MEI+YF V
Sbjct 110 VTFDLADPGTIAAAAAEILQCFGYVDVLINNAGISYRGTISDTIVDVDRKVMEINYFGPV 169
Query 122 FLTKTVLPTFIEQKSGRIAYVSSVAGLLGTQYRASYSAAKAAIHMWANSLRAEVAEFGID 181
LTK +LP+ +E+K G I +SS+ G + +R++YSA+K A + + LRAE+ E I
Sbjct 170 ALTKALLPSMVERKQGHIVAISSIQGKISIPFRSAYSASKHATQAFFDCLRAEMEEANIK 229
Query 182 VSVIFPGFVKTNVSFNALNGEGKPQGHQDEAIENGLEADVFAEEVVKALMNEEEYIVVGG 241
V+VI PG++ TN+S NA+ +G G D+ G A A++V A+ +++ +++
Sbjct 230 VTVISPGYIHTNLSVNAVTADGSRYGALDKNTAQGRSAAEVAQDVFDAVGKKKKDVLLTD 289
Query 242 AKEKLGVWISRLSPALLYKMI 262
+ V+I L+P L ++++
Sbjct 290 FVPSMAVYIRTLAPGLFFRIM 310
>Q3T0R4 Dehydrogenase/reductase SDR family member 7B [Bos taurus]
Length=325
Score = 162 bits (410), Expect = 1e-51
Identities = 89/263 (34%), Positives = 149/263 (57%), Gaps = 7/263 (3%)
Query 7 LENKVVWITGASSGLGKALARECALQGAQVVLTARRYDELEKVRFGL-------FKPEQH 59
+ N VV ITGA+SGLG+ AR GA++VL R + LE++ L + +
Sbjct 50 VRNAVVVITGATSGLGRECARVFHAAGARLVLCGRNAEALEELSQELAASRAPGVQTHKP 109
Query 60 ASVAADITDETQVRHAYEQVLAKKGRIDWLINNAGLSQRALIQDTTMQTERAIMEIDYFS 119
+V D+ D + A ++L G +D LINNAG+S R I DT+ ++ +ME +YF
Sbjct 110 CTVTFDLADPGAIAGAASEILQCFGHVDVLINNAGISYRGAIVDTSPDVDKRVMETNYFG 169
Query 120 QVFLTKTVLPTFIEQKSGRIAYVSSVAGLLGTQYRASYSAAKAAIHMWANSLRAEVAEFG 179
V LTK +LP I ++ G + +SS+ G + +R++Y+A+K A + + LRAEV +
Sbjct 170 PVALTKALLPAMIRRRQGHVVAISSIQGKISLPFRSAYAASKHATQAFFDCLRAEVEQHD 229
Query 180 IDVSVIFPGFVKTNVSFNALNGEGKPQGHQDEAIENGLEADVFAEEVVKALMNEEEYIVV 239
I+V+VI PG++ TN+S NA+ +G G DE G A++++ AL +++ +V+
Sbjct 230 IEVTVISPGYIHTNLSLNAVTADGSKYGVMDETTAQGRSPVQVAQDILAALGKKKKDVVL 289
Query 240 GGAKEKLGVWISRLSPALLYKMI 262
L V++ L+P L ++++
Sbjct 290 ADPMPSLAVYLRTLAPGLFFRLM 312
>Q5RJY4 Dehydrogenase/reductase SDR family member 7B [Rattus norvegicus]
Length=325
Score = 161 bits (407), Expect = 4e-51
Identities = 93/263 (35%), Positives = 149/263 (57%), Gaps = 7/263 (3%)
Query 7 LENKVVWITGASSGLGKALARECALQGAQVVLTARRYDELEKVRFGLF-------KPEQH 59
L N VV +TGA+SGLGK AR GA+VVL R LE+ L + Q
Sbjct 50 LRNAVVVVTGATSGLGKECARVFHAAGAKVVLCGRNVKALEEFTRELADSSSSQGQTHQP 109
Query 60 ASVAADITDETQVRHAYEQVLAKKGRIDWLINNAGLSQRALIQDTTMQTERAIMEIDYFS 119
V D+ D + A ++L G +D LINNAG+S R I DT + +R +MEI+YF
Sbjct 110 CVVTFDLADPGAIAPAAAEILQCFGYVDILINNAGISYRGAISDTIVDVDRKVMEINYFG 169
Query 120 QVFLTKTVLPTFIEQKSGRIAYVSSVAGLLGTQYRASYSAAKAAIHMWANSLRAEVAEFG 179
V LTK +LP+ +E+K G I +SS+ G + +R++Y+A+K A + + LRAE+ +
Sbjct 170 PVALTKALLPSMVERKRGHIVAISSIQGKISIPFRSAYAASKHATQAFFDCLRAEMKDSD 229
Query 180 IDVSVIFPGFVKTNVSFNALNGEGKPQGHQDEAIENGLEADVFAEEVVKALMNEEEYIVV 239
I+V+VI PG++ TN+S NA+ +G G D+ G A A+++ A+ +++ +++
Sbjct 230 IEVTVISPGYIHTNLSVNAVTADGSRYGALDKNTAQGRSAVEVAQDIFDAVGKKKKDVLL 289
Query 240 GGAKEKLGVWISRLSPALLYKMI 262
+ V+I L+P L ++++
Sbjct 290 TDFLPTMAVYIRTLAPRLFFRIM 312
>Q6IAN0 Dehydrogenase/reductase SDR family member 7B [Homo sapiens]
Length=325
Score = 160 bits (404), Expect = 1e-50
Identities = 91/263 (35%), Positives = 151/263 (57%), Gaps = 7/263 (3%)
Query 7 LENKVVWITGASSGLGKALARECALQGAQVVLTARRYDELEKVRFGLF-----KPEQHAS 61
L N VV ITGA+SGLGK A+ GA++VL R LE++ L K + H
Sbjct 50 LRNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKP 109
Query 62 --VAADITDETQVRHAYEQVLAKKGRIDWLINNAGLSQRALIQDTTMQTERAIMEIDYFS 119
V D+TD + A ++L G +D L+NNAG+S R I DTT+ ++ +ME +YF
Sbjct 110 YLVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFG 169
Query 120 QVFLTKTVLPTFIEQKSGRIAYVSSVAGLLGTQYRASYSAAKAAIHMWANSLRAEVAEFG 179
V LTK +LP+ I+++ G I +SS+ G + +R++Y+A+K A + + LRAE+ ++
Sbjct 170 PVALTKALLPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYE 229
Query 180 IDVSVIFPGFVKTNVSFNALNGEGKPQGHQDEAIENGLEADVFAEEVVKALMNEEEYIVV 239
I+V+VI PG++ TN+S NA+ +G G D G A++V+ A+ +++ +++
Sbjct 230 IEVTVISPGYIHTNLSVNAITADGSRYGVMDTTTAQGRSPVEVAQDVLAAVGKKKKDVIL 289
Query 240 GGAKEKLGVWISRLSPALLYKMI 262
L V++ L+P L + ++
Sbjct 290 ADLLPSLAVYLRTLAPGLFFSLM 312
>Q5R6U1 Dehydrogenase/reductase SDR family member 7B [Pongo abelii]
Length=325
Score = 159 bits (403), Expect = 2e-50
Identities = 91/263 (35%), Positives = 151/263 (57%), Gaps = 7/263 (3%)
Query 7 LENKVVWITGASSGLGKALARECALQGAQVVLTARRYDELEKVRFGLF-----KPEQHAS 61
L N VV ITGA+SGLGK A+ GA++VL R LE++ L K + H
Sbjct 50 LRNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKP 109
Query 62 --VAADITDETQVRHAYEQVLAKKGRIDWLINNAGLSQRALIQDTTMQTERAIMEIDYFS 119
V D+TD + A ++L G +D L+NNAG+S R I DTT+ ++ +ME +YF
Sbjct 110 YLVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFG 169
Query 120 QVFLTKTVLPTFIEQKSGRIAYVSSVAGLLGTQYRASYSAAKAAIHMWANSLRAEVAEFG 179
V LTK +LP+ I+++ G I +SS+ G + +R++Y+A+K A + + LRAE+ ++
Sbjct 170 PVALTKALLPSMIKRRQGHIVAISSIQGKISIPFRSAYAASKHATQAFFDCLRAEMEQYE 229
Query 180 IDVSVIFPGFVKTNVSFNALNGEGKPQGHQDEAIENGLEADVFAEEVVKALMNEEEYIVV 239
I+V+VI PG++ TN+S NA+ +G G D G A++V+ A+ +++ +++
Sbjct 230 IEVTVISPGYIHTNLSVNAVTADGSRYGVMDTTTAQGRSPVEVAQDVLAAVGKKKKDVIL 289
Query 240 GGAKEKLGVWISRLSPALLYKMI 262
L V++ L+P L + ++
Sbjct 290 ADLLPSLAVYLRTLAPGLFFSLM 312
>Q9Y394 Dehydrogenase/reductase SDR family member 7 [Homo sapiens]
Length=339
Score = 145 bits (366), Expect = 7e-45
Identities = 85/202 (42%), Positives = 124/202 (61%), Gaps = 6/202 (3%)
Query 7 LENKVVWITGASSGLGKALARECALQGAQVVLTARRYDELEKVRF-----GLFKPEQHAS 61
L + VVW+TGASSG+G+ LA + + G +VL+ARR ELE+V+ G K +
Sbjct 48 LTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILV 107
Query 62 VAADITDETQVRHAYEQVLAKKGRIDWLINNAGLSQRALIQDTTMQTERAIMEIDYFSQV 121
+ D+TD A + VL + GRID L+NN G+SQR+L DT++ R ++E++Y V
Sbjct 108 LPLDLTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTV 167
Query 122 FLTKTVLPTFIEQKSGRIAYVSSVAGLLGTQYRASYSAAKAAIHMWANSLRAEVAEF-GI 180
LTK VLP IE+K G+I V+S+ G++ Y A+K A+ + N LR E+A + GI
Sbjct 168 SLTKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGI 227
Query 181 DVSVIFPGFVKTNVSFNALNGE 202
VS I PG V++N+ N+L GE
Sbjct 228 IVSNICPGPVQSNIVENSLAGE 249
>A6SSW9 Oxidoreductase BOA17 [Botryotinia fuckeliana (strain B05.10)]
Length=274
Score = 117 bits (293), Expect = 8e-35
Identities = 70/184 (38%), Positives = 107/184 (58%), Gaps = 1/184 (1%)
Query 10 KVVWITGASSGLGKALARECALQGAQVVLTARRYDELEKVRFGLFKPEQHASVAADITDE 69
K+ +ITG+S GLG A+A G V+ TAR+ ++L + F E+ VA D+TD
Sbjct 3 KIWFITGSSRGLGLAIAEAALNNGDSVIATARKPEQLTNL-VNKFGKERVFPVALDVTDN 61
Query 70 TQVRHAYEQVLAKKGRIDWLINNAGLSQRALIQDTTMQTERAIMEIDYFSQVFLTKTVLP 129
QV A + K GRID +INNAG + A ++D + A +E + V+++K VLP
Sbjct 62 NQVLQAVKSGHEKFGRIDVVINNAGYANTAAVEDIDVDDFCAQVEANLMGVVYVSKAVLP 121
Query 130 TFIEQKSGRIAYVSSVAGLLGTQYRASYSAAKAAIHMWANSLRAEVAEFGIDVSVIFPGF 189
+QKSG I VSS+ G +G ++Y +AK A+ ++ L EVA FGI ++V+ PG
Sbjct 122 ILRQQKSGHIFQVSSLGGRIGAPGLSAYQSAKWAVGGFSTVLAQEVASFGIKITVLEPGG 181
Query 190 VKTN 193
++T+
Sbjct 182 IRTD 185
>Q8CHS7 Dehydrogenase/reductase SDR family member 7C [Mus musculus]
Length=311
Score = 116 bits (291), Expect = 3e-34
Identities = 75/265 (28%), Positives = 138/265 (52%), Gaps = 7/265 (3%)
Query 5 NSLENKVVWITGASSGLGKALARECALQGAQVVLTARRYDELEKVRFGLFKPEQHAS--- 61
++++NKVV IT A SGLGK AR GA++VL + ++ LE + L +
Sbjct 33 SAVQNKVVVITDAISGLGKECARVFHAGGARLVLCGKNWEGLESLYATLTSVADPSKTFT 92
Query 62 ---VAADITDETQVRHAYEQVLAKKGRIDWLINNAGLSQRALIQDTTMQTERAIMEIDYF 118
V D++D + V+ ++VL G +D LINNA + + +++ ++ IM+ +YF
Sbjct 93 PKLVLLDLSDISCVQDVAKEVLDCYGCVDILINNASVKVKGPAHKISLELDKKIMDANYF 152
Query 119 SQVFLTKTVLPTFIEQKSGRIAYVSSVAGLLGTQYRASYSAAKAAIHMWANSLRAEVAEF 178
+ LTK +LP I +++G+I V+++ G +R +Y+A+K A+ + + LRAEV E+
Sbjct 153 GPITLTKVLLPNMISRRTGQIVLVNNIQAKFGIPFRTAYAASKHAVMGFFDCLRAEVEEY 212
Query 179 GIDVSVIFPGFVKT-NVSFNALNGEGKPQGHQDEAIENGLEADVFAEEVVKALMNEEEYI 237
+ VS + P F+++ S N E + G+ AEEV++ + +++ +
Sbjct 213 DVVVSTVSPTFIRSYRASPEQRNWETSICKFFCRKLAYGVHPVEVAEEVMRTVRRKKQEV 272
Query 238 VVGGAKEKLGVWISRLSPALLYKMI 262
+ K V+I P + ++
Sbjct 273 FMANPVPKAAVFIRTFFPEFFFAVV 297
>D3ZGP9 Dehydrogenase/reductase SDR family member 7C [Rattus norvegicus]
Length=311
Score = 115 bits (288), Expect = 9e-34
Identities = 73/265 (28%), Positives = 137/265 (52%), Gaps = 7/265 (3%)
Query 5 NSLENKVVWITGASSGLGKALARECALQGAQVVLTARRYDELEKVRFGLFKPEQHAS--- 61
++++NKVV IT A SGLGK AR GA++VL + ++ LE + L +
Sbjct 33 SAVQNKVVVITDALSGLGKECARVFNAGGARLVLCGKNWEGLESLYAALTSVADPSKTFT 92
Query 62 ---VAADITDETQVRHAYEQVLAKKGRIDWLINNAGLSQRALIQDTTMQTERAIMEIDYF 118
V D++D + V ++VL G +D LINNA + + +++ ++ IM+ +YF
Sbjct 93 PKLVLLDLSDISCVEDVAKEVLDCYGCVDILINNASVKVKGPAHKISLELDKKIMDANYF 152
Query 119 SQVFLTKTVLPTFIEQKSGRIAYVSSVAGLLGTQYRASYSAAKAAIHMWANSLRAEVAEF 178
+ TK +LP I +++G+I V+++ G +R +Y+A+K A+ + + LRAEV E+
Sbjct 153 GPITFTKVLLPNMISRRTGQIVLVNNIQAKFGIPFRTAYAASKHAVMGFFDCLRAEVEEY 212
Query 179 GIDVSVIFPGFVKTNVSFNALNGEGKP-QGHQDEAIENGLEADVFAEEVVKALMNEEEYI 237
+ VS + P F+++ ++ G + G+ AEEV++ + +++ +
Sbjct 213 DVVVSTVSPTFIRSYQAYPEQRNWGSSICKFFCRKLTYGVHPVEVAEEVMRTVRRKKQEV 272
Query 238 VVGGAKEKLGVWISRLSPALLYKMI 262
+ K V+I P L + ++
Sbjct 273 FMANPVPKAAVFIRTFFPELFFAVV 297
>P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG [Escherichia
coli (strain K12)]
Length=244
Score = 107 bits (268), Expect = 2e-31
Identities = 61/190 (32%), Positives = 110/190 (58%), Gaps = 2/190 (1%)
Query 6 SLENKVVWITGASSGLGKALARECALQGAQVVLTARRYDELEKVRFGLFKPEQHASVAAD 65
+ E K+ +TGAS G+G+A+A A +GA+V+ TA + + + L + +
Sbjct 2 NFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYL--GANGKGLMLN 59
Query 66 ITDETQVRHAYEQVLAKKGRIDWLINNAGLSQRALIQDTTMQTERAIMEIDYFSQVFLTK 125
+TD + E++ A+ G +D L+NNAG+++ L+ + I+E + S L+K
Sbjct 60 VTDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFRLSK 119
Query 126 TVLPTFIEQKSGRIAYVSSVAGLLGTQYRASYSAAKAAIHMWANSLRAEVAEFGIDVSVI 185
V+ ++++ GRI + SV G +G +A+Y+AAKA + ++ SL EVA GI V+V+
Sbjct 120 AVMRAMMKKRHGRIITIGSVVGTMGNGGQANYAAAKAGLIGFSKSLAREVASRGITVNVV 179
Query 186 FPGFVKTNVS 195
PGF++T+++
Sbjct 180 APGFIETDMT 189
>Q8A945 3-ketodihydrosphingosine reductase [Bacteroides thetaiotaomicron
(strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774
/ NCTC 10582 / VPI-5482 / E50)]
Length=269
Score = 107 bits (268), Expect = 3e-31
Identities = 65/192 (34%), Positives = 107/192 (56%), Gaps = 11/192 (6%)
Query 7 LENKVVWITGASSGLGKALARECALQGAQVVLTARRYDE-LEKVRFGLFKPEQHASVAAD 65
++ +++ ITGASSG GK A+ + QG V T+R+ E + KVR + D
Sbjct 1 MQPQIILITGASSGFGKITAQMLSEQGHIVYGTSRKPSENIGKVRM----------LVVD 50
Query 66 ITDETQVRHAYEQVLAKKGRIDWLINNAGLSQRALIQDTTMQTERAIMEIDYFSQVFLTK 125
+T+ VR A EQ+++++GR+D LINNAG+ ++ T + M ++F V + K
Sbjct 51 VTNSISVRQAVEQIISEQGRMDVLINNAGMGIGGALELATEEEVSMQMNTNFFGVVNMCK 110
Query 126 TVLPTFIEQKSGRIAYVSSVAGLLGTQYRASYSAAKAAIHMWANSLRAEVAEFGIDVSVI 185
VLP + + G+I +SS+ G++G Y+ YSA+K A+ ++ +L EV F I V ++
Sbjct 111 AVLPYMRKARRGKIINISSIGGVMGIPYQGFYSASKFAVEGYSEALALEVHPFHIKVCLV 170
Query 186 FPGFVKTNVSFN 197
PG T + N
Sbjct 171 QPGDFNTGFTDN 182
>P37694 Ketoacyl reductase HetN [Nostoc sp. (strain PCC 7120 /
SAG 25.82 / UTEX 2576)]
Length=287
Score = 108 bits (269), Expect = 3e-31
Identities = 78/273 (29%), Positives = 136/273 (50%), Gaps = 27/273 (10%)
Query 4 LNSLENKVVWITGASSGLGKALARECALQGAQVVLTARRYDELEKVRFGLFKPEQHA-SV 62
+ +L K V +TGAS GLG +AR A + A VV +R L + + A ++
Sbjct 1 MTTLTGKTVLLTGASRGLGVYIARALAKEQATVVCVSRSQSGLAQTCNAVKAAGGKAIAI 60
Query 63 AADITDETQVRHAYEQVLAKKGRIDWLINNAGLSQRALIQDTTMQTERAIMEIDYFSQVF 122
D+ + +Q+ +Q G ID LINNAG+ + ++ ++I + + +
Sbjct 61 PFDVRNTSQLSALVQQAQDIVGPIDVLINNAGIEINGTFANYSLAEIQSIFNTNLLAAME 120
Query 123 LTKTVLPTFIEQKSGRIAYVSSVAGLLGTQYRASYSAAKAAIHMWANSLRAEVAEFGIDV 182
LT+ +LP+ +E+ SGRI ++S+AG G + + YSA+KA + MW +++R E+ G+++
Sbjct 121 LTRLLLPSMMERGSGRIVNIASLAGKKGVAFNSVYSASKAGLIMWTDAMRQELVGTGVNI 180
Query 183 SVIFPGFVK-------TNVSFNALNGEGKPQGHQDEAIENGLEADVFAEEVVKALMNEEE 235
SV+ PG+V T VS L G P+ A VVKA+ N+
Sbjct 181 SVVCPGYVSQTGMTVDTRVSAPKLAGISTPKS--------------VANAVVKAIKNKTT 226
Query 236 YIVVG-----GAKEKLGVWISRLSPALLYKMIR 263
++V + KL + + ++SP + ++ R
Sbjct 227 EVIVNQNPITESLTKLMLAVGQISPTSVDRIYR 259
>Q6F7B8 Fatty acyl-CoA reductase [Acinetobacter baylyi (strain
ATCC 33305 / BD413 / ADP1)]
Length=295
Score = 108 bits (269), Expect = 4e-31
Identities = 64/190 (34%), Positives = 108/190 (57%), Gaps = 3/190 (2%)
Query 6 SLENKVVWITGASSGLGKALARECALQGAQVVLTARRYDELEKVRFGLFKPEQHASV-AA 64
+++ KV ITGASSG+G +A+ A GA V+L AR + LE+V+ + + AS+
Sbjct 12 NVKGKVALITGASSGIGLTIAKRIAAAGAHVLLVARTQETLEEVKAAIEQQGGQASIFPC 71
Query 65 DITDETQVRHAYEQVLAKKGRIDWLINNAGLSQRALIQDT--TMQTERAIMEIDYFSQVF 122
D+TD + +Q++A +D+LINNAG S R + ++ M+++YF V
Sbjct 72 DLTDMNAIDQLSQQIMASVDHVDFLINNAGRSIRRAVHESFDRFHDFERTMQLNYFGAVR 131
Query 123 LTKTVLPTFIEQKSGRIAYVSSVAGLLGTQYRASYSAAKAAIHMWANSLRAEVAEFGIDV 182
L +LP I++K+G+I +SS+ L ++Y A+KAA+ ++ L AEV + I +
Sbjct 132 LVLNLLPHMIKRKNGQIINISSIGVLANATRFSAYVASKAALDAFSRCLSAEVLKHKISI 191
Query 183 SVIFPGFVKT 192
+ I+ V+T
Sbjct 192 TSIYMPLVRT 201
>P0A2C9 3-oxoacyl-[acyl-carrier-protein] reductase FabG [Salmonella
typhimurium (strain LT2 / SGSC1412 / ATCC 700720)]
Length=244
Score = 106 bits (265), Expect = 5e-31
Identities = 61/190 (32%), Positives = 107/190 (56%), Gaps = 2/190 (1%)
Query 6 SLENKVVWITGASSGLGKALARECALQGAQVVLTARRYDELEKVRFGLFKPEQHASVAAD 65
S E K+ +TGAS G+G+A+A +GA+V+ TA + + + L + +
Sbjct 2 SFEGKIALVTGASRGIGRAIAETLVARGAKVIGTATSENGAKNISDYL--GANGKGLMLN 59
Query 66 ITDETQVRHAYEQVLAKKGRIDWLINNAGLSQRALIQDTTMQTERAIMEIDYFSQVFLTK 125
+TD + E + A+ G +D L+NNAG+++ L+ I+E + S L+K
Sbjct 60 VTDPASIESVLENIRAEFGEVDILVNNAGITRDNLLMRMKDDEWNDIIETNLSSVFRLSK 119
Query 126 TVLPTFIEQKSGRIAYVSSVAGLLGTQYRASYSAAKAAIHMWANSLRAEVAEFGIDVSVI 185
V+ ++++ GRI + SV G +G +A+Y+AAKA + ++ SL EVA GI V+V+
Sbjct 120 AVMRAMMKKRCGRIITIGSVVGTMGNAGQANYAAAKAGLIGFSKSLAREVASRGITVNVV 179
Query 186 FPGFVKTNVS 195
PGF++T+++
Sbjct 180 APGFIETDMT 189
Lambda K H a alpha
0.320 0.133 0.376 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1094261
Database: 0e99ec8e4b33b2e93b4544f429c87e63.SwissProt.fasta
Posted date: May 19, 2024 10:32 PM
Number of letters in database: 5,781
Number of sequences in database: 19
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
