BLASTP 2.12.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: c419ee2bb14c0ffe232f8e56687402fc.SwissProt.fasta
           13 sequences; 9,233 total letters



Query= ACIAD3078

Length=485
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

P0C188 NAD(P) transhydrogenase subunit beta [Rhodospirillum rubrum]   485     2e-172
Q2RSB4 NAD(P) transhydrogenase subunit beta [Rhodospirillum rubru...  485     2e-172
P43010 NAD(P) transhydrogenase subunit beta [Haemophilus influenz...  443     5e-156
P0AB70 NAD(P) transhydrogenase subunit beta [Shigella flexneri]       435     5e-153
P0AB68 NAD(P) transhydrogenase subunit beta [Escherichia coli O6:...  435     5e-153
P0AB69 NAD(P) transhydrogenase subunit beta [Escherichia coli O15...  435     5e-153
P0AB67 NAD(P) transhydrogenase subunit beta [Escherichia coli (st...  435     5e-153
Q13423 NAD(P) transhydrogenase, mitochondrial [Homo sapiens]          347     4e-112
Q61941 NAD(P) transhydrogenase, mitochondrial [Mus musculus]          346     1e-111
W5PFI3 NAD(P) transhydrogenase, mitochondrial [Ovis aries]            345     3e-111
P11024 NAD(P) transhydrogenase, mitochondrial [Bos taurus]            344     5e-111
Q95046 Chaperonin HSP60, mitochondrial [Trypanosoma cruzi]            40.4    2e-06 
Q91WF3 Adenylate cyclase type 4 [Mus musculus]                        37.7    1e-05 


>P0C188 NAD(P) transhydrogenase subunit beta [Rhodospirillum rubrum]
Length=464

 Score = 485 bits (1248),  Expect = 2e-172
 Identities = 253/471 (54%), Positives = 338/471 (72%), Gaps = 18/471 (4%)

Query  12   YLIGAVLFIMTLRGLSGPKTAISGNRYGMIGMAIAVLTTFFVADHPVVWMIVGAMVLGAI  71
            Y++  VLFI+ LRGLS P++A +GNR GM+GMAIA+LTT           IV A+ +G  
Sbjct  10   YIVAGVLFILALRGLSNPESARNGNRMGMVGMAIAILTTLLSPSVQAYAWIVLAIAIGGA  69

Query  72   VGIVRARTVPMTQMPETVALMHSLVGLAAVLIAIAAILHNNQLTVLFEQNEAALTAAGVQ  131
            +G V A+ V MT +P+ VA  HSLVG+AAVL+A  A+L+              + +AG  
Sbjct  70   IGTVIAKKVLMTALPQLVAAFHSLVGMAAVLVATGALLNPEAY---------GIGSAGAI  120

Query  132  HAHMSPVHLFELFVGCFVGAITFTASVFAYGKLAAKKWAKTISGAWVKPVQAIIFIAMLA  191
            HA      L E+ +G  VGAITF+ SV A+GKL      K ++     P+ A++ I ++ 
Sbjct  121  HAGS----LVEMSLGLAVGAITFSGSVIAFGKLQGLIAGKPVTFPMQHPLNAVLGILLVV  176

Query  192  CGFYFFSTGNMTAFWAMTILALAFGWVWIAPVGGGDMPVVVSLLNSFSGWAAAGIGFTLE  251
                F +T + TA++A+ ILA A G++ I P+GG DMPVV+S+LNS+SGWAAAGIGFTL 
Sbjct  177  LLVVFAATESHTAYFALMILAFALGFLLIIPIGGADMPVVISMLNSYSGWAAAGIGFTLG  236

Query  252  NNMLIVAGSLVGSSGAILSYIMCKAMNRNILNVLFGG--AMGGAAVAGAAKGEQVQRNHR  309
            N +LI+AG+LVGSSGAILSYIMCK MNR+I NV+ GG  + GG A AG A G+   R+ +
Sbjct  237  NPLLIIAGALVGSSGAILSYIMCKGMNRSIFNVILGGFGSEGGVAAAGGAAGD---RSVK  293

Query  310  SGSADDAGFLMSNADSVVIVPGYGMAQGRAQNAVKELCELLKEQGVKVRFAIHPVAGRMP  369
            +GSA+DA F+M NA  V+IVPGYGMA  +AQ+A++E+ ++LK++GV+V +AIHPVAGRMP
Sbjct  294  AGSAEDAAFIMKNASKVIIVPGYGMAVAQAQHALREMADVLKKEGVEVSYAIHPVAGRMP  353

Query  370  GHMNVLLAEADVAYEDILEMDEINSDFPATDVVLVIGANDVVNPAAKDDPSSPIYGMPIL  429
            GHMNVLLAEA+V Y+++ E++EINS F   DV  VIGANDV NPAAK DPSSPIYGMPIL
Sbjct  354  GHMNVLLAEANVPYDEVFELEEINSSFQTADVAFVIGANDVTNPAAKTDPSSPIYGMPIL  413

Query  430  EAHKARTIMVIKRSMATGYAGLDNDLFYNEKTMMIFGDAKKVVEDMTKAIN  480
            +  KA T++ IKRSMA+GYAG++N+LF+   TMM+FGDAKK+ E + +A+N
Sbjct  414  DVEKAGTVLFIKRSMASGYAGVENELFFRNNTMMLFGDAKKMTEQIVQAMN  464


>Q2RSB4 NAD(P) transhydrogenase subunit beta [Rhodospirillum rubrum 
(strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / 
NCIMB 8255 / S1)]
Length=464

 Score = 485 bits (1248),  Expect = 2e-172
 Identities = 253/471 (54%), Positives = 338/471 (72%), Gaps = 18/471 (4%)

Query  12   YLIGAVLFIMTLRGLSGPKTAISGNRYGMIGMAIAVLTTFFVADHPVVWMIVGAMVLGAI  71
            Y++  VLFI+ LRGLS P++A +GNR GM+GMAIA+LTT           IV A+ +G  
Sbjct  10   YIVAGVLFILALRGLSNPESARNGNRMGMVGMAIAILTTLLSPSVQAYAWIVLAIAIGGA  69

Query  72   VGIVRARTVPMTQMPETVALMHSLVGLAAVLIAIAAILHNNQLTVLFEQNEAALTAAGVQ  131
            +G V A+ V MT +P+ VA  HSLVG+AAVL+A  A+L+              + +AG  
Sbjct  70   IGTVIAKKVLMTALPQLVAAFHSLVGMAAVLVATGALLNPEAY---------GIGSAGAI  120

Query  132  HAHMSPVHLFELFVGCFVGAITFTASVFAYGKLAAKKWAKTISGAWVKPVQAIIFIAMLA  191
            HA      L E+ +G  VGAITF+ SV A+GKL      K ++     P+ A++ I ++ 
Sbjct  121  HAGS----LVEMSLGLAVGAITFSGSVIAFGKLQGLIAGKPVTFPMQHPLNAVLGILLVV  176

Query  192  CGFYFFSTGNMTAFWAMTILALAFGWVWIAPVGGGDMPVVVSLLNSFSGWAAAGIGFTLE  251
                F +T + TA++A+ ILA A G++ I P+GG DMPVV+S+LNS+SGWAAAGIGFTL 
Sbjct  177  LLVVFAATESHTAYFALMILAFALGFLLIIPIGGADMPVVISMLNSYSGWAAAGIGFTLG  236

Query  252  NNMLIVAGSLVGSSGAILSYIMCKAMNRNILNVLFGG--AMGGAAVAGAAKGEQVQRNHR  309
            N +LI+AG+LVGSSGAILSYIMCK MNR+I NV+ GG  + GG A AG A G+   R+ +
Sbjct  237  NPLLIIAGALVGSSGAILSYIMCKGMNRSIFNVILGGFGSEGGVAAAGGAAGD---RSVK  293

Query  310  SGSADDAGFLMSNADSVVIVPGYGMAQGRAQNAVKELCELLKEQGVKVRFAIHPVAGRMP  369
            +GSA+DA F+M NA  V+IVPGYGMA  +AQ+A++E+ ++LK++GV+V +AIHPVAGRMP
Sbjct  294  AGSAEDAAFIMKNASKVIIVPGYGMAVAQAQHALREMADVLKKEGVEVSYAIHPVAGRMP  353

Query  370  GHMNVLLAEADVAYEDILEMDEINSDFPATDVVLVIGANDVVNPAAKDDPSSPIYGMPIL  429
            GHMNVLLAEA+V Y+++ E++EINS F   DV  VIGANDV NPAAK DPSSPIYGMPIL
Sbjct  354  GHMNVLLAEANVPYDEVFELEEINSSFQTADVAFVIGANDVTNPAAKTDPSSPIYGMPIL  413

Query  430  EAHKARTIMVIKRSMATGYAGLDNDLFYNEKTMMIFGDAKKVVEDMTKAIN  480
            +  KA T++ IKRSMA+GYAG++N+LF+   TMM+FGDAKK+ E + +A+N
Sbjct  414  DVEKAGTVLFIKRSMASGYAGVENELFFRNNTMMLFGDAKKMTEQIVQAMN  464


>P43010 NAD(P) transhydrogenase subunit beta [Haemophilus influenzae 
(strain ATCC 51907 / DSM 11121 / KW20 / Rd)]
Length=474

 Score = 443 bits (1140),  Expect = 5e-156
 Identities = 243/472 (51%), Positives = 326/472 (69%), Gaps = 11/472 (2%)

Query  12   YLIGAVLFIMTLRGLSGPKTAISGNRYGMIGMAIAVLTTFFVADHPVVWMIVGAMVLGAI  71
            Y++ A+LFIM+L GLS  +TA +G  +G++GM IA++ T F       + I+ AM++G  
Sbjct  10   YILAALLFIMSLAGLSKHETAKAGCWFGIVGMTIALIATIFGPHSEGTFWIIIAMIIGGA  69

Query  72   VGIVRARTVPMTQMPETVALMHSLVGLAAVLIAIAAI-LHNNQLTVLFEQNEAALTAAGV  130
            +G+ RA  V MT+MPE VA++HS VGLAAVL+   +  LH+  L  + E  +AA  AA V
Sbjct  70   IGVQRALKVEMTEMPELVAILHSFVGLAAVLVGFNSYGLHHEAL--MPEGLDAAAQAAFV  127

Query  131  -QHAHMSPVHLFELFVGCFVGAITFTASVFAYGKLAAKKWAKTISGAWVKPVQ--AIIFI  187
             + A ++ +H  E+F+G F+GA+TFT SV A+GKL+ K  +K +       +   A++  
Sbjct  128  AEQAVLTNIHNVEVFLGIFIGAVTFTGSVVAFGKLSGKINSKALMLPHRHKLNLAALVVS  187

Query  188  AMLACGFYFFSTGNMTAFWAMTILALAFGWVWIAPVGGGDMPVVVSLLNSFSGWAAAGIG  247
            A+L   F   +  ++     MT +ALAFGW  +A +GG DMPVVVS+LNS+SGWAAA  G
Sbjct  188  ALLMVAF-LNNPESIFPVLLMTAIALAFGWHLVASIGGADMPVVVSMLNSYSGWAAAAAG  246

Query  248  FTLENNMLIVAGSLVGSSGAILSYIMCKAMNRNILNVLFGGAMGGAAVAGAAKGEQVQRN  307
            F L N++LIV G+LVGSSGAILSYIMCKAMNR+ ++V+ GG      V+ + +    Q  
Sbjct  247  FILNNDLLIVTGALVGSSGAILSYIMCKAMNRSFVSVIAGGFGNDVQVSSSEE----QGE  302

Query  308  HRSGSADDAGFLMSNADSVVIVPGYGMAQGRAQNAVKELCELLKEQGVKVRFAIHPVAGR  367
            HR  +A++   L+ NA SV+I PGYGMA  +AQ  V ++   L+E+GV VRF IHPVAGR
Sbjct  303  HRETTAEEVAELLKNASSVIITPGYGMAVAQAQYPVADITAKLRERGVNVRFGIHPVAGR  362

Query  368  MPGHMNVLLAEADVAYEDILEMDEINSDFPATDVVLVIGANDVVNPAAKDDPSSPIYGMP  427
            +PGHMNVLLAEA V Y+ +LEMDEIN DF  TDVVLVIGAND VNPAA +DP+SPI GMP
Sbjct  363  LPGHMNVLLAEAKVPYDVVLEMDEINDDFADTDVVLVIGANDTVNPAAMEDPNSPIAGMP  422

Query  428  ILEAHKARTIMVIKRSMATGYAGLDNDLFYNEKTMMIFGDAKKVVEDMTKAI  479
            +LE  KA+ ++V KRSMA GYAG+ N LF+ E T M+FGDAK  VED+ KA+
Sbjct  423  VLEVWKAQNVIVFKRSMAVGYAGVQNPLFFKENTQMLFGDAKDRVEDILKAL  474


>P0AB70 NAD(P) transhydrogenase subunit beta [Shigella flexneri]
Length=462

 Score = 435 bits (1119),  Expect = 5e-153
 Identities = 242/481 (50%), Positives = 317/481 (66%), Gaps = 41/481 (9%)

Query  12   YLIGAVLFIMTLRGLSGPKTAISGNRYGMIGMAIAVLTTFFVADHPVVWMIVGAMVLGAI  71
            Y++ A+LFI +L GLS  +T+  GN +G+ GMAIA++ T F  D   V  I+ AMV+G  
Sbjct  10   YIVAAILFIFSLAGLSKHETSRQGNNFGIAGMAIALIATIFGPDTGNVGWILLAMVIGGA  69

Query  72   VGIVRARTVPMTQMPETVALMHSLVGLAAVLIAIAAILHNNQLTVLFEQNEAALTAAGVQ  131
            +GI  A+ V MT+MPE VA++HS VGLAAVL+   + LH++                   
Sbjct  70   IGIRLAKKVEMTEMPELVAILHSFVGLAAVLVGFNSYLHHD-------------------  110

Query  132  HAHMSPV----HLFELFVGCFVGAITFTASVFAYGKLAAKKWAKTISGAWVKPVQAIIFI  187
             A M+P+    HL E+F+G F+GA+TFT SV A+GKL  K  +K +    + P +  + +
Sbjct  111  -AGMAPILVNIHLTEVFLGIFIGAVTFTGSVVAFGKLCGKISSKPL----MLPNRHKMNL  165

Query  188  AMLACGFYFF-------STG-NMTAFWAMTILALAFGWVWIAPVGGGDMPVVVSLLNSFS  239
            A L   F          S G  + A   MT +AL FGW  +A +GG DMPVVVS+LNS+S
Sbjct  166  AALVVSFLLLIVFVRTDSVGLQVLALLIMTAIALVFGWHLVASIGGADMPVVVSMLNSYS  225

Query  240  GWAAAGIGFTLENNMLIVAGSLVGSSGAILSYIMCKAMNRNILNVLFGGAMGGAAVAGAA  299
            GWAAA  GF L N++LIV G+LVGSSGAILSYIMCKAMNR+ ++V+     GG    G++
Sbjct  226  GWAAAAAGFMLSNDLLIVTGALVGSSGAILSYIMCKAMNRSFISVI----AGGFGTDGSS  281

Query  300  KGE-QVQRNHRSGSADDAGFLMSNADSVVIVPGYGMAQGRAQNAVKELCELLKEQGVKVR  358
             G+ Q    HR  +A++   L+ N+ SV+I PGYGMA  +AQ  V E+ E L+ +G+ VR
Sbjct  282  TGDDQEVGEHREITAEETAELLKNSHSVIITPGYGMAVAQAQYPVAEITEKLRARGINVR  341

Query  359  FAIHPVAGRMPGHMNVLLAEADVAYEDILEMDEINSDFPATDVVLVIGANDVVNPAAKDD  418
            F IHPVAGR+PGHMNVLLAEA V Y+ +LEMDEIN DF  TD VLVIGAND VNPAA+DD
Sbjct  342  FGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDTVLVIGANDTVNPAAQDD  401

Query  419  PSSPIYGMPILEAHKARTIMVIKRSMATGYAGLDNDLFYNEKTMMIFGDAKKVVEDMTKA  478
            P SPI GMP+LE  KA+ ++V KRSM TGYAG+ N LF+ E T M+FGDAK  V+ + KA
Sbjct  402  PKSPIAGMPVLEVWKAQNVIVFKRSMNTGYAGVQNPLFFKENTHMLFGDAKASVDAILKA  461

Query  479  I  479
            +
Sbjct  462  L  462


>P0AB68 NAD(P) transhydrogenase subunit beta [Escherichia coli 
O6:H1 (strain CFT073 / ATCC 700928 / UPEC)]
Length=462

 Score = 435 bits (1119),  Expect = 5e-153
 Identities = 242/481 (50%), Positives = 317/481 (66%), Gaps = 41/481 (9%)

Query  12   YLIGAVLFIMTLRGLSGPKTAISGNRYGMIGMAIAVLTTFFVADHPVVWMIVGAMVLGAI  71
            Y++ A+LFI +L GLS  +T+  GN +G+ GMAIA++ T F  D   V  I+ AMV+G  
Sbjct  10   YIVAAILFIFSLAGLSKHETSRQGNNFGIAGMAIALIATIFGPDTGNVGWILLAMVIGGA  69

Query  72   VGIVRARTVPMTQMPETVALMHSLVGLAAVLIAIAAILHNNQLTVLFEQNEAALTAAGVQ  131
            +GI  A+ V MT+MPE VA++HS VGLAAVL+   + LH++                   
Sbjct  70   IGIRLAKKVEMTEMPELVAILHSFVGLAAVLVGFNSYLHHD-------------------  110

Query  132  HAHMSPV----HLFELFVGCFVGAITFTASVFAYGKLAAKKWAKTISGAWVKPVQAIIFI  187
             A M+P+    HL E+F+G F+GA+TFT SV A+GKL  K  +K +    + P +  + +
Sbjct  111  -AGMAPILVNIHLTEVFLGIFIGAVTFTGSVVAFGKLCGKISSKPL----MLPNRHKMNL  165

Query  188  AMLACGFYFF-------STG-NMTAFWAMTILALAFGWVWIAPVGGGDMPVVVSLLNSFS  239
            A L   F          S G  + A   MT +AL FGW  +A +GG DMPVVVS+LNS+S
Sbjct  166  AALVVSFLLLIVFVRTDSVGLQVLALLIMTAIALVFGWHLVASIGGADMPVVVSMLNSYS  225

Query  240  GWAAAGIGFTLENNMLIVAGSLVGSSGAILSYIMCKAMNRNILNVLFGGAMGGAAVAGAA  299
            GWAAA  GF L N++LIV G+LVGSSGAILSYIMCKAMNR+ ++V+     GG    G++
Sbjct  226  GWAAAAAGFMLSNDLLIVTGALVGSSGAILSYIMCKAMNRSFISVI----AGGFGTDGSS  281

Query  300  KGE-QVQRNHRSGSADDAGFLMSNADSVVIVPGYGMAQGRAQNAVKELCELLKEQGVKVR  358
             G+ Q    HR  +A++   L+ N+ SV+I PGYGMA  +AQ  V E+ E L+ +G+ VR
Sbjct  282  TGDDQEVGEHREITAEETAELLKNSHSVIITPGYGMAVAQAQYPVAEITEKLRARGINVR  341

Query  359  FAIHPVAGRMPGHMNVLLAEADVAYEDILEMDEINSDFPATDVVLVIGANDVVNPAAKDD  418
            F IHPVAGR+PGHMNVLLAEA V Y+ +LEMDEIN DF  TD VLVIGAND VNPAA+DD
Sbjct  342  FGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDTVLVIGANDTVNPAAQDD  401

Query  419  PSSPIYGMPILEAHKARTIMVIKRSMATGYAGLDNDLFYNEKTMMIFGDAKKVVEDMTKA  478
            P SPI GMP+LE  KA+ ++V KRSM TGYAG+ N LF+ E T M+FGDAK  V+ + KA
Sbjct  402  PKSPIAGMPVLEVWKAQNVIVFKRSMNTGYAGVQNPLFFKENTHMLFGDAKASVDAILKA  461

Query  479  I  479
            +
Sbjct  462  L  462


>P0AB69 NAD(P) transhydrogenase subunit beta [Escherichia coli 
O157:H7]
Length=462

 Score = 435 bits (1119),  Expect = 5e-153
 Identities = 242/481 (50%), Positives = 317/481 (66%), Gaps = 41/481 (9%)

Query  12   YLIGAVLFIMTLRGLSGPKTAISGNRYGMIGMAIAVLTTFFVADHPVVWMIVGAMVLGAI  71
            Y++ A+LFI +L GLS  +T+  GN +G+ GMAIA++ T F  D   V  I+ AMV+G  
Sbjct  10   YIVAAILFIFSLAGLSKHETSRQGNNFGIAGMAIALIATIFGPDTGNVGWILLAMVIGGA  69

Query  72   VGIVRARTVPMTQMPETVALMHSLVGLAAVLIAIAAILHNNQLTVLFEQNEAALTAAGVQ  131
            +GI  A+ V MT+MPE VA++HS VGLAAVL+   + LH++                   
Sbjct  70   IGIRLAKKVEMTEMPELVAILHSFVGLAAVLVGFNSYLHHD-------------------  110

Query  132  HAHMSPV----HLFELFVGCFVGAITFTASVFAYGKLAAKKWAKTISGAWVKPVQAIIFI  187
             A M+P+    HL E+F+G F+GA+TFT SV A+GKL  K  +K +    + P +  + +
Sbjct  111  -AGMAPILVNIHLTEVFLGIFIGAVTFTGSVVAFGKLCGKISSKPL----MLPNRHKMNL  165

Query  188  AMLACGFYFF-------STG-NMTAFWAMTILALAFGWVWIAPVGGGDMPVVVSLLNSFS  239
            A L   F          S G  + A   MT +AL FGW  +A +GG DMPVVVS+LNS+S
Sbjct  166  AALVVSFLLLIVFVRTDSVGLQVLALLIMTAIALVFGWHLVASIGGADMPVVVSMLNSYS  225

Query  240  GWAAAGIGFTLENNMLIVAGSLVGSSGAILSYIMCKAMNRNILNVLFGGAMGGAAVAGAA  299
            GWAAA  GF L N++LIV G+LVGSSGAILSYIMCKAMNR+ ++V+     GG    G++
Sbjct  226  GWAAAAAGFMLSNDLLIVTGALVGSSGAILSYIMCKAMNRSFISVI----AGGFGTDGSS  281

Query  300  KGE-QVQRNHRSGSADDAGFLMSNADSVVIVPGYGMAQGRAQNAVKELCELLKEQGVKVR  358
             G+ Q    HR  +A++   L+ N+ SV+I PGYGMA  +AQ  V E+ E L+ +G+ VR
Sbjct  282  TGDDQEVGEHREITAEETAELLKNSHSVIITPGYGMAVAQAQYPVAEITEKLRARGINVR  341

Query  359  FAIHPVAGRMPGHMNVLLAEADVAYEDILEMDEINSDFPATDVVLVIGANDVVNPAAKDD  418
            F IHPVAGR+PGHMNVLLAEA V Y+ +LEMDEIN DF  TD VLVIGAND VNPAA+DD
Sbjct  342  FGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDTVLVIGANDTVNPAAQDD  401

Query  419  PSSPIYGMPILEAHKARTIMVIKRSMATGYAGLDNDLFYNEKTMMIFGDAKKVVEDMTKA  478
            P SPI GMP+LE  KA+ ++V KRSM TGYAG+ N LF+ E T M+FGDAK  V+ + KA
Sbjct  402  PKSPIAGMPVLEVWKAQNVIVFKRSMNTGYAGVQNPLFFKENTHMLFGDAKASVDAILKA  461

Query  479  I  479
            +
Sbjct  462  L  462


>P0AB67 NAD(P) transhydrogenase subunit beta [Escherichia coli 
(strain K12)]
Length=462

 Score = 435 bits (1119),  Expect = 5e-153
 Identities = 242/481 (50%), Positives = 317/481 (66%), Gaps = 41/481 (9%)

Query  12   YLIGAVLFIMTLRGLSGPKTAISGNRYGMIGMAIAVLTTFFVADHPVVWMIVGAMVLGAI  71
            Y++ A+LFI +L GLS  +T+  GN +G+ GMAIA++ T F  D   V  I+ AMV+G  
Sbjct  10   YIVAAILFIFSLAGLSKHETSRQGNNFGIAGMAIALIATIFGPDTGNVGWILLAMVIGGA  69

Query  72   VGIVRARTVPMTQMPETVALMHSLVGLAAVLIAIAAILHNNQLTVLFEQNEAALTAAGVQ  131
            +GI  A+ V MT+MPE VA++HS VGLAAVL+   + LH++                   
Sbjct  70   IGIRLAKKVEMTEMPELVAILHSFVGLAAVLVGFNSYLHHD-------------------  110

Query  132  HAHMSPV----HLFELFVGCFVGAITFTASVFAYGKLAAKKWAKTISGAWVKPVQAIIFI  187
             A M+P+    HL E+F+G F+GA+TFT SV A+GKL  K  +K +    + P +  + +
Sbjct  111  -AGMAPILVNIHLTEVFLGIFIGAVTFTGSVVAFGKLCGKISSKPL----MLPNRHKMNL  165

Query  188  AMLACGFYFF-------STG-NMTAFWAMTILALAFGWVWIAPVGGGDMPVVVSLLNSFS  239
            A L   F          S G  + A   MT +AL FGW  +A +GG DMPVVVS+LNS+S
Sbjct  166  AALVVSFLLLIVFVRTDSVGLQVLALLIMTAIALVFGWHLVASIGGADMPVVVSMLNSYS  225

Query  240  GWAAAGIGFTLENNMLIVAGSLVGSSGAILSYIMCKAMNRNILNVLFGGAMGGAAVAGAA  299
            GWAAA  GF L N++LIV G+LVGSSGAILSYIMCKAMNR+ ++V+     GG    G++
Sbjct  226  GWAAAAAGFMLSNDLLIVTGALVGSSGAILSYIMCKAMNRSFISVI----AGGFGTDGSS  281

Query  300  KGE-QVQRNHRSGSADDAGFLMSNADSVVIVPGYGMAQGRAQNAVKELCELLKEQGVKVR  358
             G+ Q    HR  +A++   L+ N+ SV+I PGYGMA  +AQ  V E+ E L+ +G+ VR
Sbjct  282  TGDDQEVGEHREITAEETAELLKNSHSVIITPGYGMAVAQAQYPVAEITEKLRARGINVR  341

Query  359  FAIHPVAGRMPGHMNVLLAEADVAYEDILEMDEINSDFPATDVVLVIGANDVVNPAAKDD  418
            F IHPVAGR+PGHMNVLLAEA V Y+ +LEMDEIN DF  TD VLVIGAND VNPAA+DD
Sbjct  342  FGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDTVLVIGANDTVNPAAQDD  401

Query  419  PSSPIYGMPILEAHKARTIMVIKRSMATGYAGLDNDLFYNEKTMMIFGDAKKVVEDMTKA  478
            P SPI GMP+LE  KA+ ++V KRSM TGYAG+ N LF+ E T M+FGDAK  V+ + KA
Sbjct  402  PKSPIAGMPVLEVWKAQNVIVFKRSMNTGYAGVQNPLFFKENTHMLFGDAKASVDAILKA  461

Query  479  I  479
            +
Sbjct  462  L  462


>Q13423 NAD(P) transhydrogenase, mitochondrial [Homo sapiens]
Length=1086

 Score = 347 bits (891),  Expect = 4e-112
 Identities = 203/473 (43%), Positives = 287/473 (61%), Gaps = 33/473 (7%)

Query  12    YLIGAVLFIMTLRGLSGPKTAISGNRYGMIGMAIAVLTTFFVADH--PVVWMIVGAMVLG  69
             YL   +  +  L GLS   TA  GN  GMIG+A  +  T  V      ++  + GAM LG
Sbjct  624   YLGSGLCCVGALAGLSTQGTARLGNALGMIGVAGGLAATLGVLKPGPELLAQMSGAMALG  683

Query  70    AIVGIVRARTVPMTQMPETVALMHSLVGLAAVLIAIAAILHNNQLTVLFEQNEAALTAAG  129
               +G+  A+ + ++ +P+ VA  HSLVGLAAVL  IA  +         E    A  AA 
Sbjct  684   GTIGLTIAKRIQISDLPQLVAAFHSLVGLAAVLTCIAEYI--------IEYPHFATDAA-  734

Query  130   VQHAHMSPVHLFELFVGCFVGAITFTASVFAYGKLAAKKWAKTISGAWVKPVQAIIFIAM  189
                A+++ +     ++G ++G +TF+ S+ AYGKL         S   + P + ++   +
Sbjct  735   ---ANLTKI---VAYLGTYIGGVTFSGSLIAYGKLQGL----LKSAPLLLPGRHLLNAGL  784

Query  190   LACGFY---------FFSTGNMTAFWAMTILALAFGWVWIAPVGGGDMPVVVSLLNSFSG  240
             LA              F+TG +T   +++ L+   G    A +GG DMPVV+++LNS+SG
Sbjct  785   LAASVGGIIPFMVDPSFTTG-ITCLGSVSALSAVMGVTLTAAIGGADMPVVITVLNSYSG  843

Query  241   WAAAGIGFTLENNMLIVAGSLVGSSGAILSYIMCKAMNRNILNVLFGGAMGGAAVAGAAK  300
             WA    GF L NN+L + G+L+GSSGAILSYIMC AMNR++ NV+ GG  G  + AG  K
Sbjct  844   WALCAEGFLLNNNLLTIVGALIGSSGAILSYIMCVAMNRSLANVILGG-YGTTSTAGG-K  901

Query  301   GEQVQRNHRSGSADDAGFLMSNADSVVIVPGYGMAQGRAQNAVKELCELLKEQGVKVRFA  360
               ++   H   + D+A  ++  A+S++I PGYG+   +AQ  + +L ++L EQG KVRF 
Sbjct  902   PMEISGTHTEINLDNAIDMIREANSIIITPGYGLCAAKAQYPIADLVKMLTEQGKKVRFG  961

Query  361   IHPVAGRMPGHMNVLLAEADVAYEDILEMDEINSDFPATDVVLVIGANDVVNPAAKDDPS  420
             IHPVAGRMPG +NVLLAEA V Y+ +LEMDEIN DFP TD+VLVIGAND VN AA++DP+
Sbjct  962   IHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINHDFPDTDLVLVIGANDTVNSAAQEDPN  1021

Query  421   SPIYGMPILEAHKARTIMVIKRSMATGYAGLDNDLFYNEKTMMIFGDAKKVVE  473
             S I GMP+LE  K++ ++V+KRS+  GYA +DN +FY   T M+ GDAKK  +
Sbjct  1022  SIIAGMPVLEVWKSKQVIVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCD  1074


 Score = 21.9 bits (45),  Expect = 0.93
 Identities = 9/17 (53%), Positives = 12/17 (71%), Gaps = 0/17 (0%)

Query  284  VLFGGAMGGAAVAGAAK  300
            ++ GG + G A AGAAK
Sbjct  231  LIVGGGVAGLASAGAAK  247


 Score = 21.9 bits (45),  Expect = 0.93
 Identities = 10/21 (48%), Positives = 14/21 (67%), Gaps = 0/21 (0%)

Query  429  LEAHKARTIMVIKRSMATGYA  449
            LEA KA TI   +++M+T  A
Sbjct  458  LEAEKAATITPFRKTMSTASA  478


 Score = 18.9 bits (37),  Expect = 8.2
 Identities = 10/25 (40%), Positives = 16/25 (64%), Gaps = 1/25 (4%)

Query  261  LVGSSGAILSYIMCKAMNRNILNVL  285
            L+ +SG ++S+I   A N  +LN L
Sbjct  144  LLKTSGTLISFIY-PAQNPELLNKL  167


>Q61941 NAD(P) transhydrogenase, mitochondrial [Mus musculus]
Length=1086

 Score = 346 bits (888),  Expect = 1e-111
 Identities = 202/472 (43%), Positives = 284/472 (60%), Gaps = 25/472 (5%)

Query  9     EWFYLIGAVLFIMTLRGLSGPKTAISGNRYGMIGMAIAVLTTF--FVADHPVVWMIVGAM  66
             E  YL   +  +  L GLS   TA  GN  GMIG+A  +  T      D  ++  + GAM
Sbjct  621   EIMYLGSGLCCVGALGGLSTQGTARLGNALGMIGVAGGLAATLGGLKPDPQLLAQMSGAM  680

Query  67    VLGAIVGIVRARTVPMTQMPETVALMHSLVGLAAVLIAIAAILHNNQLTVLFEQNEAALT  126
              +G  +G+  A+ + ++ +P+ VA  HSLVGLAAVL  +A  +         E    A+ 
Sbjct  681   AMGGTIGLTIAKRIQISDLPQLVAAFHSLVGLAAVLTCMAEYI--------VEYPHFAMD  732

Query  127   AAGVQHAHMSPVHLFELFVGCFVGAITFTASVFAYGKLAAKKWAKTISGAWVKPVQAIIF  186
             A        S       ++G ++G +TF+ S+ AYGKL     +  +       + A + 
Sbjct  733   AT-------SNFTKIVAYLGTYIGGVTFSGSLVAYGKLQGILKSAPLLLPGRHALNAGLL  785

Query  187   IAMLACGFYF-----FSTGNMTAFWAMTILALAFGWVWIAPVGGGDMPVVVSLLNSFSGW  241
              A +     F     F+TG +T   +++ L+   G    A +GG DMPVV+++LNS+SGW
Sbjct  786   AASVGGIIPFMADPSFTTG-ITCLGSVSGLSTLMGVTLTAAIGGADMPVVITVLNSYSGW  844

Query  242   AAAGIGFTLENNMLIVAGSLVGSSGAILSYIMCKAMNRNILNVLFGGAMGGAAVAGAAKG  301
             A    GF L NN+L + G+L+GSSGAILSYIMC AMNR++ NV+ GG  G  + AG  K 
Sbjct  845   ALCAEGFLLNNNLLTIVGALIGSSGAILSYIMCVAMNRSLANVILGG-YGTTSTAGG-KP  902

Query  302   EQVQRNHRSGSADDAGFLMSNADSVVIVPGYGMAQGRAQNAVKELCELLKEQGVKVRFAI  361
              ++   H   + D+A  ++  A+S+VI PGYG+   +AQ  + +L ++L EQG KVRF I
Sbjct  903   MEISGTHTEINLDNAVEMIREANSIVITPGYGLCAAKAQYPIADLVKMLTEQGKKVRFGI  962

Query  362   HPVAGRMPGHMNVLLAEADVAYEDILEMDEINSDFPATDVVLVIGANDVVNPAAKDDPSS  421
             HPVAGRMPG +NVLLAEA V Y+ +LEMDEINSDFP TD+VLVIGAND VN AA++DP+S
Sbjct  963   HPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINSDFPDTDLVLVIGANDTVNSAAQEDPNS  1022

Query  422   PIYGMPILEAHKARTIMVIKRSMATGYAGLDNDLFYNEKTMMIFGDAKKVVE  473
              I GMP+LE  K++ ++V+KRS+  GYA +DN +FY   T M+ GDAKK  +
Sbjct  1023  IIAGMPVLEVWKSKQVIVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCD  1074


 Score = 21.9 bits (45),  Expect = 0.93
 Identities = 9/17 (53%), Positives = 12/17 (71%), Gaps = 0/17 (0%)

Query  284  VLFGGAMGGAAVAGAAK  300
            ++ GG + G A AGAAK
Sbjct  231  LIVGGGVAGLASAGAAK  247


>W5PFI3 NAD(P) transhydrogenase, mitochondrial [Ovis aries]
Length=1086

 Score = 345 bits (885),  Expect = 3e-111
 Identities = 202/473 (43%), Positives = 286/473 (60%), Gaps = 33/473 (7%)

Query  12    YLIGAVLFIMTLRGLSGPKTAISGNRYGMIGMAIAVLTTF--FVADHPVVWMIVGAMVLG  69
             YL   +  +  L GLS   TA  GN  GMIG+A  +  T         ++  + GAM LG
Sbjct  624   YLGSGLCCVGALAGLSTQGTARLGNALGMIGVAGGLAATLGGLKPCPELLAQMSGAMALG  683

Query  70    AIVGIVRARTVPMTQMPETVALMHSLVGLAAVLIAIAAILHNNQLTVLFEQNEAALTAAG  129
               +G+  A+ + ++ +P+ VA  HSLVGLAAVL  IA  +         E    A  AA 
Sbjct  684   GTIGLTIAKRIQISDLPQLVAAFHSLVGLAAVLTCIAEYI--------IEYPHFATDAA-  734

Query  130   VQHAHMSPVHLFELFVGCFVGAITFTASVFAYGKLAAKKWAKTISGAWVKPVQAIIFIAM  189
                A+++ +     ++G ++G +TF+ S+ AYGKL         S   + P + ++   +
Sbjct  735   ---ANLTKI---VAYLGTYIGGVTFSGSLVAYGKLQGI----LKSAPLLLPGRHLLNAGL  784

Query  190   LACGFY---------FFSTGNMTAFWAMTILALAFGWVWIAPVGGGDMPVVVSLLNSFSG  240
             LA              F+TG +T   +++ L+   G    A +GG DMPVV+++LNS+SG
Sbjct  785   LAASVGGIIPFMMDPSFTTG-ITCLGSVSALSAVMGVTLTAAIGGADMPVVITVLNSYSG  843

Query  241   WAAAGIGFTLENNMLIVAGSLVGSSGAILSYIMCKAMNRNILNVLFGGAMGGAAVAGAAK  300
             WA    GF L NN+L + G+L+GSSGAILSYIMC AMNR++ NV+ GG  G  + AG  K
Sbjct  844   WALCAEGFLLNNNLLTIVGALIGSSGAILSYIMCVAMNRSLANVILGG-YGTTSTAGG-K  901

Query  301   GEQVQRNHRSGSADDAGFLMSNADSVVIVPGYGMAQGRAQNAVKELCELLKEQGVKVRFA  360
               ++   H   + D+A  ++  A+S++I PGYG+   +AQ  + +L ++L EQG KVRF 
Sbjct  902   PMEISGTHTEINLDNAIDMIREANSIIITPGYGLCAAKAQYPIADLVKMLSEQGKKVRFG  961

Query  361   IHPVAGRMPGHMNVLLAEADVAYEDILEMDEINSDFPATDVVLVIGANDVVNPAAKDDPS  420
             IHPVAGRMPG +NVLLAEA V Y+ +LEMDEIN DFP TD+VLVIGAND VN AA++DP+
Sbjct  962   IHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINHDFPDTDLVLVIGANDTVNSAAQEDPN  1021

Query  421   SPIYGMPILEAHKARTIMVIKRSMATGYAGLDNDLFYNEKTMMIFGDAKKVVE  473
             S I GMP+LE  K++ ++V+KRS+  GYA +DN +FY   T M+ GDAKK  +
Sbjct  1022  SIIAGMPVLEVWKSKQVIVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCD  1074


 Score = 21.9 bits (45),  Expect = 0.93
 Identities = 9/17 (53%), Positives = 12/17 (71%), Gaps = 0/17 (0%)

Query  284  VLFGGAMGGAAVAGAAK  300
            ++ GG + G A AGAAK
Sbjct  231  LIVGGGVAGLASAGAAK  247


 Score = 19.2 bits (38),  Expect = 6.3
 Identities = 10/25 (40%), Positives = 17/25 (68%), Gaps = 1/25 (4%)

Query  261  LVGSSGAILSYIMCKAMNRNILNVL  285
            L+ +SG ++S+I   A N ++LN L
Sbjct  144  LLKTSGTLISFIY-PAQNPDLLNKL  167


>P11024 NAD(P) transhydrogenase, mitochondrial [Bos taurus]
Length=1086

 Score = 344 bits (883),  Expect = 5e-111
 Identities = 203/473 (43%), Positives = 285/473 (60%), Gaps = 33/473 (7%)

Query  12    YLIGAVLFIMTLRGLSGPKTAISGNRYGMIGMAIAVLTTF--FVADHPVVWMIVGAMVLG  69
             YL   +  +  L GLS   TA  GN  GMIG+A  +  T         ++  + GAM LG
Sbjct  624   YLGSGLCCVGALAGLSTQGTARLGNALGMIGVAGGLAATLGGLKPCPELLAQMSGAMALG  683

Query  70    AIVGIVRARTVPMTQMPETVALMHSLVGLAAVLIAIAAILHNNQLTVLFEQNEAALTAAG  129
               +G+  A+ + ++ +P+ VA  HSLVGLAAVL  IA  +         E    A  AA 
Sbjct  684   GTIGLTIAKRIQISDLPQLVAAFHSLVGLAAVLTCIAEYI--------IEYPHFATDAA-  734

Query  130   VQHAHMSPVHLFELFVGCFVGAITFTASVFAYGKLAAKKWAKTI---------SGAWVKP  180
                A+++ +     ++G ++G +TF+ S+ AYGKL     +  +         +G     
Sbjct  735   ---ANLTKI---VAYLGTYIGGVTFSGSLVAYGKLQGILKSAPLLLPGRHLLNAGLLAGS  788

Query  181   VQAIIFIAMLACGFYFFSTGNMTAFWAMTILALAFGWVWIAPVGGGDMPVVVSLLNSFSG  240
             V  II   M       F+TG +T   +++ L+   G    A +GG DMPVV+++LNS+SG
Sbjct  789   VGGIIPFMMDPS----FTTG-ITCLGSVSALSAVMGVTLTAAIGGADMPVVITVLNSYSG  843

Query  241   WAAAGIGFTLENNMLIVAGSLVGSSGAILSYIMCKAMNRNILNVLFGGAMGGAAVAGAAK  300
             WA    GF L NN+L + G+L+GSSGAILSYIMC AMNR++ NV+ GG  G  + AG  K
Sbjct  844   WALCAEGFLLNNNLLTIVGALIGSSGAILSYIMCVAMNRSLANVILGG-YGTTSTAGG-K  901

Query  301   GEQVQRNHRSGSADDAGFLMSNADSVVIVPGYGMAQGRAQNAVKELCELLKEQGVKVRFA  360
               ++   H   + D+A  ++  A+S++I PGYG+   +AQ  + +L ++L EQG KVRF 
Sbjct  902   PMEISGTHTEINLDNAIDMIREANSIIITPGYGLCAAKAQYPIADLVKMLSEQGKKVRFG  961

Query  361   IHPVAGRMPGHMNVLLAEADVAYEDILEMDEINSDFPATDVVLVIGANDVVNPAAKDDPS  420
             IHPVAGRMPG +NVLLAEA V Y+ +LEMDEIN DFP TD+VLVIGAND VN AA++DP+
Sbjct  962   IHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINHDFPDTDLVLVIGANDTVNSAAQEDPN  1021

Query  421   SPIYGMPILEAHKARTIMVIKRSMATGYAGLDNDLFYNEKTMMIFGDAKKVVE  473
             S I GMP+LE  K++ ++V+KRS+  GYA +DN +FY   T M+ GDAKK  +
Sbjct  1022  SIIAGMPVLEVWKSKQVIVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCD  1074


 Score = 21.9 bits (45),  Expect = 0.93
 Identities = 9/17 (53%), Positives = 12/17 (71%), Gaps = 0/17 (0%)

Query  284  VLFGGAMGGAAVAGAAK  300
            ++ GG + G A AGAAK
Sbjct  231  LIVGGGVAGLASAGAAK  247


 Score = 19.2 bits (38),  Expect = 6.3
 Identities = 10/25 (40%), Positives = 17/25 (68%), Gaps = 1/25 (4%)

Query  261  LVGSSGAILSYIMCKAMNRNILNVL  285
            L+ +SG ++S+I   A N ++LN L
Sbjct  144  LLKTSGTLISFIY-PAQNPDLLNKL  167


>Q95046 Chaperonin HSP60, mitochondrial [Trypanosoma cruzi]
Length=562

 Score = 40.4 bits (93),  Expect = 2e-06
 Identities = 39/126 (31%), Positives = 53/126 (42%), Gaps = 7/126 (6%)

Query  278  NRNILNVLFGGAMGGAAVAGAAKGEQVQRNHRSGSADDAGFLMSNADSVVIVPGYGMAQG  337
            NR  L        GG AV     G +V+ N +     DA      A    IVPG G+A  
Sbjct  371  NREKLQERLAKLSGGVAVIKVGGGSEVEVNEKKDRITDALCSTRAAVQEGIVPGGGVALL  430

Query  338  RAQNAVKEL---CELLKEQGVKVRFAIHPVAGRMPGHMNVLLA--EADVAYEDILEMDEI  392
            RA  A+  L     L  +Q   V+   + V  R+P H  VL A  E  V  E +LE +++
Sbjct  431  RASKALDSLLGDSSLTADQRTGVQIIRNAV--RLPAHTIVLNAGKEGAVVVEKVLENNDV  488

Query  393  NSDFPA  398
               + A
Sbjct  489  TVGYDA  494


>Q91WF3 Adenylate cyclase type 4 [Mus musculus]
Length=1077

 Score = 37.7 bits (86),  Expect = 1e-05
 Identities = 33/123 (27%), Positives = 55/123 (45%), Gaps = 14/123 (11%)

Query  177  WVKPVQAIIFIAMLACGFYFFSTGNMTAFWAMT--ILALAFGWVWIAPVGGGDMP---VV  231
            W +P+  +I++A+LA G+ F  TG + + W      L + F    + P+G  D     V+
Sbjct  88   WTRPLSGLIWVALLALGYGFLFTGGVVSAWDQVSFFLFIIFTVYAMLPLGMRDAAAAGVI  147

Query  232  VSL-----LNSFSGW----AAAGIGFTLENNMLIVAGSLVGSSGAILSYIMCKAMNRNIL  282
             SL     L  + GW      A +     N +L + G++VG+    L     +A  R  L
Sbjct  148  SSLSHLLVLGLYLGWQPESQRALLPQLAANAVLFLCGNVVGAYHKALMERALRATFREAL  207

Query  283  NVL  285
            + L
Sbjct  208  SSL  210



Lambda      K        H        a         alpha
   0.325    0.137    0.413    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 3676861


  Database: c419ee2bb14c0ffe232f8e56687402fc.SwissProt.fasta
    Posted date:  Jun 1, 2024  4:56 PM
  Number of letters in database: 9,233
  Number of sequences in database:  13



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40