BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: d5662047d1bae898c9bcfd30e1b0ecf4.SwissProt.fasta
15 sequences; 5,996 total letters
Query= ACIAD1413
Length=435
Score E
Sequences producing significant alignments: (Bits) Value
P45867 Acyl-CoA dehydrogenase [Bacillus subtilis (strain 168)] 157 3e-47
P45857 Acyl-CoA dehydrogenase [Bacillus subtilis (strain 168)] 147 1e-43
Q06319 Acyl-CoA dehydrogenase, short-chain specific [Megasphaera ... 145 1e-42
P9WQG1 Probable acyl-CoA dehydrogenase FadE25 [Mycobacterium tube... 144 3e-42
P9WQG0 Probable acyl-CoA dehydrogenase fadE25 [Mycobacterium tube... 144 3e-42
P63428 Probable acyl-CoA dehydrogenase fadE25 [Mycobacterium bovi... 144 3e-42
O34421 Probable acyl-CoA dehydrogenase YngJ [Bacillus subtilis (s... 143 7e-42
G3KIM8 Acryloyl-CoA reductase (NADH) [Anaerotignum propionicum] 142 1e-41
Q54RR5 Probable short/branched chain specific acyl-CoA dehydrogen... 142 2e-41
P52042 Acyl-CoA dehydrogenase, short-chain specific [Clostridium ... 140 5e-41
P45954 Short/branched chain specific acyl-CoA dehydrogenase, mito... 140 1e-40
Q5RF40 Short/branched chain specific acyl-CoA dehydrogenase, mito... 139 4e-40
Q2LQN9 Cyclohex-1-ene-1-carbonyl-CoA dehydrogenase [Syntrophus ac... 135 6e-39
Q3ZBF6 Short-chain specific acyl-CoA dehydrogenase, mitochondrial... 135 8e-39
P70584 Short/branched chain specific acyl-CoA dehydrogenase, mito... 134 4e-38
>P45867 Acyl-CoA dehydrogenase [Bacillus subtilis (strain 168)]
Length=379
Score = 157 bits (397), Expect = 3e-47
Identities = 108/363 (30%), Positives = 191/363 (53%), Gaps = 17/363 (5%)
Query 79 DLSLTEEQTMTREAMSRFAQDVLMQIAHDADHHARFPEELWQYLEDLGLNYYALPESLGG 138
+ SL+EE M R+ + FA+ + A + D RF EL++ + +LGL PE GG
Sbjct 2 NFSLSEEHEMIRKLVRDFAKHEVAPTAAERDEQERFDRELFREMANLGLTGIPWPEDYGG 61
Query 139 VASEQNIVSNILIAEDLAQGDFSLSAGLLSTFSVIN-ALTRWGSESTQSKYLTAFSEDPN 197
+ S+ ++ ++ E+L++ S L + S+ + L +G+E +++YLT +
Sbjct 62 IGSDY--LAYVIAVEELSKVCASTGVTLSAHISLCSWPLFAFGTEEQKTEYLTQLALGEK 119
Query 198 LKATFATQENTPAFNPFKLKTQATLQNNHYFLSGEKTLVILGESADLILVTAMLDGQPE- 256
+ A FA E + +KT A + Y L+G K + G AD+ +V A+ D + +
Sbjct 120 IGA-FALTEAGSGSDAGSMKTTAERIGDDYVLNGSKVFITNGGVADIYIVFAVTDPEKKK 178
Query 257 ----VFIVERD--PTISIKSAPAMGLKAAQTMSLYFDH--TPAVL-LGDNDFDYSAF--- 304
FIVE+D + K +G++++ T + F+ PA LG+ +
Sbjct 179 KGVTAFIVEKDFEGFFTGKKEKKLGIRSSPTTEIMFEDCVVPASKRLGEEGEGFKIAMKT 238
Query 305 IDLGSLMWCAMAVGTCEAVKSYCIAYANDRTAFGEPISHRQSVAFMIADMAIEIDAMRML 364
+D G A AVG + + YA +R FG+ I+ +Q +AF +ADMA I+A R+L
Sbjct 239 LDGGRNGIAAQAVGIAQGALDAALQYAKERKQFGKSIAEQQGIAFKLADMATMIEASRLL 298
Query 365 IWNAASLAEAGQAFHREAYLARLLCAEKSMRIGTDGVQLLGGHGFTKEHPVERWYRDLRA 424
+ AA L +G + + + +++L+ + +M++ T+ VQ+ GG+G+TK++PVER+ RD +
Sbjct 299 TYQAAWLESSGLPYGKASAMSKLMAGDTAMKVTTEAVQIFGGYGYTKDYPVERYMRDAKI 358
Query 425 TAI 427
T I
Sbjct 359 TQI 361
>P45857 Acyl-CoA dehydrogenase [Bacillus subtilis (strain 168)]
Length=379
Score = 147 bits (372), Expect = 1e-43
Identities = 109/362 (30%), Positives = 185/362 (51%), Gaps = 17/362 (5%)
Query 80 LSLTEEQTMTREAMSRFAQDVLMQIAHDADHHARFPEELWQYLEDLGLNYYALPESLGGV 139
+ +T+EQ M R+ + FA+ + A + FP +L + + GL +PE GG
Sbjct 1 MHVTQEQVMMRKMVRDFARKEIAPAAEIMEKTDEFPFQLIKKMGKHGLMGIPVPEQYGGA 60
Query 140 ASEQNIVSNILIAEDLAQGDFSLSAGLLSTFSV-INALTRWGSESTQSKYLTAFSEDPNL 198
++ +VS IL ++++ ++ L SV N + +G+E + KY+ + +L
Sbjct 61 GAD--VVSYILAIHEISRISAAVGVILSVHTSVGTNPILYFGNEEQKMKYIPNLASGDHL 118
Query 199 KATFATQENTPAFNPFKLKTQATLQNNHYFLSGEKTLVILGESADLIL---VTAMLDGQP 255
A FA E + L+T A +N Y L+G K + G +AD+ + +TA G+
Sbjct 119 GA-FALTEPHSGSDAGSLRTTAIKKNGKYLLNGSKIFITNGGAADIYITFALTAPDQGRH 177
Query 256 EV--FIVERD-PTISI-KSAPAMGLKAAQTMSLYFDHTP---AVLLGDNDFDYS---AFI 305
+ FIVE++ P ++ K +GL + T L FD+ A LLG + A +
Sbjct 178 GISAFIVEKNTPGFTVGKKERKLGLYGSNTTELIFDNAEVPEANLLGKEGDGFHIAMANL 237
Query 306 DLGSLMWCAMAVGTCEAVKSYCIAYANDRTAFGEPISHRQSVAFMIADMAIEIDAMRMLI 365
++G + A A+G EA + + YA R FG PI+ Q ++F +ADMA +A R L+
Sbjct 238 NVGRIGIAAQALGIAEAALEHAVDYAKQRVQFGRPIAANQGISFKLADMATRAEAARHLV 297
Query 366 WNAASLAEAGQAFHREAYLARLLCAEKSMRIGTDGVQLLGGHGFTKEHPVERWYRDLRAT 425
++AA L G +EA +A+ ++ +++ D VQ+ GG+G+ K++PVER RD + T
Sbjct 298 YHAADLHNRGLNCGKEASMAKQFASDAAVKAALDAVQIYGGYGYMKDYPVERLLRDAKVT 357
Query 426 AI 427
I
Sbjct 358 QI 359
>Q06319 Acyl-CoA dehydrogenase, short-chain specific [Megasphaera
elsdenii]
Length=383
Score = 145 bits (366), Expect = 1e-42
Identities = 108/365 (30%), Positives = 181/365 (50%), Gaps = 17/365 (5%)
Query 79 DLSLTEEQTMTREAMSRFAQDVLMQIAHDADHHARFPEELWQYLEDLGLNYYALPESLGG 138
D +LT+ Q + F + L + DH + +EL L LG+ E GG
Sbjct 2 DFNLTDIQQDFLKLAHDFGEKKLAPTVTERDHKGIYDKELIDELLSLGITGAYFEEKYGG 61
Query 139 VASEQ-NIVSNILIAEDLAQGDFSLSAGLLSTFSVI-NALTRWGSESTQSKYLTAFSEDP 196
+ +++S IL E+LA+ D ++ L +T S+ N + ++G+E+ + K+L E
Sbjct 62 SGDDGGDVLSYILAVEELAKYDAGVAITLSATVSLCANPIWQFGTEAQKEKFLVPLVEGT 121
Query 197 NLKATFATQENTPAFNPFKLKTQATLQNNHYFLSGEKTLVILGESADLILVTAMLDGQP- 255
L A T+ N + + Y L+G K + G +AD+ +V AM D
Sbjct 122 KLGAFGLTEPNAGTDASGQQTIATKNDDGTYTLNGSKIFITNGGAADIYIVFAMTDKSKG 181
Query 256 ----EVFIVERDPTISI---KSAPAMGLKAAQTMSLYFDHT--PAV-LLGDNDFDYSAF- 304
FI+E D T K MG+ +QTM L F PA +LG+ +
Sbjct 182 NHGITAFILE-DGTPGFTYGKKEDKMGIHTSQTMELVFQDVKVPAENMLGEEGKGFKIAM 240
Query 305 --IDLGSLMWCAMAVGTCEAVKSYCIAYANDRTAFGEPISHRQSVAFMIADMAIEIDAMR 362
+D G + A A+G EA + + Y+ R FG+P+ QS++F +ADM ++I+A R
Sbjct 241 MTLDGGRIGVAAQALGIAEAALADAVEYSKQRVQFGKPLCKFQSISFKLADMKMQIEAAR 300
Query 363 MLIWNAASLAEAGQAFHREAYLARLLCAEKSMRIGTDGVQLLGGHGFTKEHPVERWYRDL 422
L++ AA + G+ F +A +A+ + ++ +MR+ T+ VQ+ GG+G+++E+PV R RD
Sbjct 301 NLVYKAACKKQEGKPFTVDAAIAKRVASDVAMRVTTEAVQIFGGYGYSEEYPVARHMRDA 360
Query 423 RATAI 427
+ T I
Sbjct 361 KITQI 365
>P9WQG1 Probable acyl-CoA dehydrogenase FadE25 [Mycobacterium
tuberculosis (strain ATCC 25618 / H37Rv)]
Length=389
Score = 144 bits (363), Expect = 3e-42
Identities = 112/369 (30%), Positives = 183/369 (50%), Gaps = 26/369 (7%)
Query 78 FDL-SLTEEQTMTREAMSRFAQDVLMQIAHDADHHARFPEELWQYLEDLGLNYYALPESL 136
FDL L EE R A+ A+ + A + D ARFPEE L G N +PE
Sbjct 10 FDLFKLPEEHDEMRSAIRALAEKEIAPHAAEVDEKARFPEEALVALNSSGFNAVHIPEEY 69
Query 137 GGVASEQNIVSNILIAEDLAQGDFSLSA-GLLSTFSVINALTRWGSESTQSKYLTAFSED 195
GG ++ V+ ++ E++A+ D S S ++ + + R GSE + + L A + +
Sbjct 70 GGQGADS--VATCIVIEEVARVDASASLIPAVNKLGTMGLILR-GSEELKKQVLPALAAE 126
Query 196 PNLKATFATQENTPAFNPFKLKTQATLQNNHYFLSGEKTLVILGESADLILVTAMLDGQP 255
+ A++A E + ++T+A +H+ L+G K + G + V A+ D
Sbjct 127 GAM-ASYALSEREAGSDAASMRTRAKADGDHWILNGAKCWITNGGKSTWYTVMAVTDPDR 185
Query 256 -----EVFIVERDP---TISIKSAPAMGLKAAQTMSLYFDHTPAV---LLGDNDFDYS-- 302
F+V +D T+ K +G+K + T LYF++ ++G+ +
Sbjct 186 GANGISAFMVHKDDEGFTVGPKERK-LGIKGSPTTELYFENCRIPGDRIIGEPGTGFKTA 244
Query 303 -AFIDLGSLMWCAMAVGTCEAVKSYCIAYANDRTAFGEPISHRQSVAFMIADMAIEIDAM 361
A +D A AVG + IAY DR FGE IS Q+V FM+ADMA++++A
Sbjct 245 LATLDHTRPTIGAQAVGIAQGALDAAIAYTKDRKQFGESISTFQAVQFMLADMAMKVEAA 304
Query 362 RMLIWNAASLAEAGQ---AFHREAYLARLLCAEKSMRIGTDGVQLLGGHGFTKEHPVERW 418
R+++++AA+ AE G+ F A ++ ++ +M + TD VQL GG G+T + PVER+
Sbjct 305 RLMVYSAAARAERGEPDLGFISAA--SKCFASDVAMEVTTDAVQLFGGAGYTTDFPVERF 362
Query 419 YRDLRATAI 427
RD + T I
Sbjct 363 MRDAKITQI 371
>P9WQG0 Probable acyl-CoA dehydrogenase fadE25 [Mycobacterium
tuberculosis (strain CDC 1551 / Oshkosh)]
Length=389
Score = 144 bits (363), Expect = 3e-42
Identities = 112/369 (30%), Positives = 183/369 (50%), Gaps = 26/369 (7%)
Query 78 FDL-SLTEEQTMTREAMSRFAQDVLMQIAHDADHHARFPEELWQYLEDLGLNYYALPESL 136
FDL L EE R A+ A+ + A + D ARFPEE L G N +PE
Sbjct 10 FDLFKLPEEHDEMRSAIRALAEKEIAPHAAEVDEKARFPEEALVALNSSGFNAVHIPEEY 69
Query 137 GGVASEQNIVSNILIAEDLAQGDFSLSA-GLLSTFSVINALTRWGSESTQSKYLTAFSED 195
GG ++ V+ ++ E++A+ D S S ++ + + R GSE + + L A + +
Sbjct 70 GGQGADS--VATCIVIEEVARVDASASLIPAVNKLGTMGLILR-GSEELKKQVLPALAAE 126
Query 196 PNLKATFATQENTPAFNPFKLKTQATLQNNHYFLSGEKTLVILGESADLILVTAMLDGQP 255
+ A++A E + ++T+A +H+ L+G K + G + V A+ D
Sbjct 127 GAM-ASYALSEREAGSDAASMRTRAKADGDHWILNGAKCWITNGGKSTWYTVMAVTDPDR 185
Query 256 -----EVFIVERDP---TISIKSAPAMGLKAAQTMSLYFDHTPAV---LLGDNDFDYS-- 302
F+V +D T+ K +G+K + T LYF++ ++G+ +
Sbjct 186 GANGISAFMVHKDDEGFTVGPKERK-LGIKGSPTTELYFENCRIPGDRIIGEPGTGFKTA 244
Query 303 -AFIDLGSLMWCAMAVGTCEAVKSYCIAYANDRTAFGEPISHRQSVAFMIADMAIEIDAM 361
A +D A AVG + IAY DR FGE IS Q+V FM+ADMA++++A
Sbjct 245 LATLDHTRPTIGAQAVGIAQGALDAAIAYTKDRKQFGESISTFQAVQFMLADMAMKVEAA 304
Query 362 RMLIWNAASLAEAGQ---AFHREAYLARLLCAEKSMRIGTDGVQLLGGHGFTKEHPVERW 418
R+++++AA+ AE G+ F A ++ ++ +M + TD VQL GG G+T + PVER+
Sbjct 305 RLMVYSAAARAERGEPDLGFISAA--SKCFASDVAMEVTTDAVQLFGGAGYTTDFPVERF 362
Query 419 YRDLRATAI 427
RD + T I
Sbjct 363 MRDAKITQI 371
>P63428 Probable acyl-CoA dehydrogenase fadE25 [Mycobacterium
bovis (strain ATCC BAA-935 / AF2122/97)]
Length=389
Score = 144 bits (363), Expect = 3e-42
Identities = 112/369 (30%), Positives = 183/369 (50%), Gaps = 26/369 (7%)
Query 78 FDL-SLTEEQTMTREAMSRFAQDVLMQIAHDADHHARFPEELWQYLEDLGLNYYALPESL 136
FDL L EE R A+ A+ + A + D ARFPEE L G N +PE
Sbjct 10 FDLFKLPEEHDEMRSAIRALAEKEIAPHAAEVDEKARFPEEALVALNSSGFNAVHIPEEY 69
Query 137 GGVASEQNIVSNILIAEDLAQGDFSLSA-GLLSTFSVINALTRWGSESTQSKYLTAFSED 195
GG ++ V+ ++ E++A+ D S S ++ + + R GSE + + L A + +
Sbjct 70 GGQGADS--VATCIVIEEVARVDASASLIPAVNKLGTMGLILR-GSEELKKQVLPALAAE 126
Query 196 PNLKATFATQENTPAFNPFKLKTQATLQNNHYFLSGEKTLVILGESADLILVTAMLDGQP 255
+ A++A E + ++T+A +H+ L+G K + G + V A+ D
Sbjct 127 GAM-ASYALSEREAGSDAASMRTRAKADGDHWILNGAKCWITNGGKSTWYTVMAVTDPDR 185
Query 256 -----EVFIVERDP---TISIKSAPAMGLKAAQTMSLYFDHTPAV---LLGDNDFDYS-- 302
F+V +D T+ K +G+K + T LYF++ ++G+ +
Sbjct 186 GANGISAFMVHKDDEGFTVGPKERK-LGIKGSPTTELYFENCRIPGDRIIGEPGTGFKTA 244
Query 303 -AFIDLGSLMWCAMAVGTCEAVKSYCIAYANDRTAFGEPISHRQSVAFMIADMAIEIDAM 361
A +D A AVG + IAY DR FGE IS Q+V FM+ADMA++++A
Sbjct 245 LATLDHTRPTIGAQAVGIAQGALDAAIAYTKDRKQFGESISTFQAVQFMLADMAMKVEAA 304
Query 362 RMLIWNAASLAEAGQ---AFHREAYLARLLCAEKSMRIGTDGVQLLGGHGFTKEHPVERW 418
R+++++AA+ AE G+ F A ++ ++ +M + TD VQL GG G+T + PVER+
Sbjct 305 RLMVYSAAARAERGEPDLGFISAA--SKCFASDVAMEVTTDAVQLFGGAGYTTDFPVERF 362
Query 419 YRDLRATAI 427
RD + T I
Sbjct 363 MRDAKITQI 371
>O34421 Probable acyl-CoA dehydrogenase YngJ [Bacillus subtilis
(strain 168)]
Length=380
Score = 143 bits (360), Expect = 7e-42
Identities = 110/364 (30%), Positives = 178/364 (49%), Gaps = 18/364 (5%)
Query 79 DLSLTEEQTMTREAMSRFAQDVLMQIAHDADHHARFPEELWQYLEDLGLNYYALPESLGG 138
+ LT+EQ M RE + FA+ + A D FP + ++ + +LGL PE GG
Sbjct 2 NFELTKEQQMVREMVKDFAKKEIAPHAEHVDQTGEFPMQTFKKMGELGLMGIPFPEEYGG 61
Query 139 VASEQNIVSNILIAEDLAQGDFSLSAGLLSTFSV-INALTRWGSESTQSKYLTAFSEDPN 197
S + +S L E++ + S + S+ + L +G+E + +LT +
Sbjct 62 --SGGDTISYALAVEEVGKACGSTGLSYAAAVSLGASPLYYFGTEEQKQTHLTPLASGTA 119
Query 198 LKATFATQENTPAFNPFKLKTQATLQNNHYFLSGEKTLVILGESADLILVTAML----DG 253
L +F E + +T+A + Y ++GEK + A ++VTA+ DG
Sbjct 120 L-GSFGLTEPNAGSDAGGTQTKAISNGDEYVINGEKCWITNASYARTVIVTAVTGKNKDG 178
Query 254 QPEV--FIVERD-PTISIKSA-PAMGLKAAQTMSLYFD--HTPAV-LLGDNDFDYSAFI- 305
+ + IV D P ++I S MG++ + T + + PA LLGD + F+
Sbjct 179 KNIISALIVPTDTPGLTITSPYDKMGVRGSNTAEILLEDVRVPAANLLGDPTKGFKQFLY 238
Query 306 --DLGSLMWCAMAVGTCEAVKSYCIAYANDRTAFGEPISHRQSVAFMIADMAIEIDAMRM 363
D G + A+AVG +A +AYA +R FG+PIS Q++ F +ADMA+EID R
Sbjct 239 TLDGGRISIAALAVGIAQAALDASLAYAKERKQFGQPISSFQAIQFKLADMAMEIDLARQ 298
Query 364 LIWNAASLAEAGQAFHREAYLARLLCAEKSMRIGTDGVQLLGGHGFTKEHPVERWYRDLR 423
++ AA L + + F +EA A+L +E + R +Q+ GG G+ KE+ VER RD +
Sbjct 299 MVLKAAWLKDHNRPFTKEAAYAKLFASEMATRACNQAIQIHGGSGYMKEYGVERMLRDAK 358
Query 424 ATAI 427
I
Sbjct 359 LMEI 362
>G3KIM8 Acryloyl-CoA reductase (NADH) [Anaerotignum propionicum]
Length=394
Score = 142 bits (359), Expect = 1e-41
Identities = 106/375 (28%), Positives = 185/375 (49%), Gaps = 20/375 (5%)
Query 69 RLPKQNKSIFDLSLTEEQTMTREAMSRFAQDVLMQIAHDADHHARFPEELWQYLEDLGLN 128
++ K+ D SLT EQ M ++ +FA+ L +A + D FP E ++ + ++GL
Sbjct 5 KIKKERMKRMDFSLTREQEMLKKLARQFAEIELEPVAEEIDREHVFPAENFKKMAEIGLT 64
Query 129 YYALPESLGGVASEQNIVSNILIAEDLAQGDFSLSAGLLSTFSVI-NALTRWGSESTQSK 187
+P+ GG S + ++ + + + SA +LS + A+ ++G++ +
Sbjct 65 GIGIPKEFGG--SGGGTLEKVIAVSEFGKKCMA-SASILSIHLIAPQAIYKYGTKEQKET 121
Query 188 YLTAFSEDPNLKATFATQENTPAFNPFKLKTQATL--QNNHYFLSGEKTLVILGESADLI 245
YL ++ L A FA E + +KT A L Q N Y L+G K + G A ++
Sbjct 122 YLPRLTKGGELGA-FALTEPNAGSDAGAVKTTAILDSQTNEYVLNGTKCFISGGGRAGVL 180
Query 246 LVTAM------LDGQPEVFIVERDPTISI-KSAPAMGLKAAQTMSLYFD--HTPAV-LLG 295
++ A+ L G + + + P SI K MG+ ++T L F+ PA LLG
Sbjct 181 VIFALTEPKKGLKGMSAIIVEKGTPGFSIGKVESKMGIAGSETAELIFEDCRVPAANLLG 240
Query 296 DNDFDYSAF---IDLGSLMWCAMAVGTCEAVKSYCIAYANDRTAFGEPISHRQSVAFMIA 352
+ +D + A A+G E + Y ++R FG+PI++ Q + + IA
Sbjct 241 KEGKGFKIAMEALDGARIGVGAQAIGIAEGAIDLSVKYVHERIQFGKPIANLQGIQWYIA 300
Query 353 DMAIEIDAMRMLIWNAASLAEAGQAFHREAYLARLLCAEKSMRIGTDGVQLLGGHGFTKE 412
DMA + A R L+ AA L +AG+ F +E+ + +L +E + + +Q+ GG+G+ K+
Sbjct 301 DMATKTAAARALVEFAAYLEDAGKPFTKESAMCKLNASENARFVTNLALQIHGGYGYMKD 360
Query 413 HPVERWYRDLRATAI 427
+P+ER YRD + T I
Sbjct 361 YPLERMYRDAKITEI 375
>Q54RR5 Probable short/branched chain specific acyl-CoA dehydrogenase
[Dictyostelium discoideum]
Length=413
Score = 142 bits (359), Expect = 2e-41
Identities = 106/362 (29%), Positives = 187/362 (52%), Gaps = 19/362 (5%)
Query 81 SLTEEQTMTREAMSRFAQDVLMQIAHDADHHARFPEELWQYLEDLGLNYYALPESLGGVA 140
+L+EE+T+ +E ++ FA + + + D + + L + L D+ L + +S GG
Sbjct 34 TLSEEETLLKETVANFANEKVRPLVKVMDETSELNKGLLKDLFDMNLMGIDISDSYGG-- 91
Query 141 SEQNIVSNILIAEDLAQGDFSLSAGL-LSTFSVINALTRWGSESTQSKYLTAFSEDPNLK 199
+ N + +I+ E+LA+ D ++S + + V N + R+GS + KYL+ + N
Sbjct 92 ANMNFMGSIIAIEELAKVDPAISVIVDVQNTLVNNCINRYGSIQQREKYLSMLAT--NTV 149
Query 200 ATFATQENTPAFNPFKLKTQATLQNNHYF-LSGEKTLVILGESADLILVTAMLDGQP--- 255
+F E+ + F L T+A Q++ F L+G K + + A + +V A +D
Sbjct 150 GSFCLSESGSGSDAFALATRAVRQSDGTFVLNGTKQWITNAKEAGVFIVMANVDPSQGYK 209
Query 256 --EVFIVE-RDPTISI-KSAPAMGLKAAQTMSLYFDHT---PAVLLGDNDFDYSAFID-- 306
FIVE +P + I K +G++A+ T + D+ P +LG+ Y I+
Sbjct 210 GITAFIVESNNPGLRIGKKEDKLGIRASSTCEVILDNCVVKPTDILGELGRGYKIAIEGL 269
Query 307 -LGSLMWCAMAVGTCEAVKSYCIAYANDRTAFGEPISHRQSVAFMIADMAIEIDAMRMLI 365
G + A +G + V I Y +R FG+PI+ Q + F AD+A++I+A R+L
Sbjct 270 NEGRIGIAAQMLGLAQGVFDSTIPYLMERKQFGKPIATFQGMQFTYADLAVDIEAGRLLT 329
Query 366 WNAASLAEAGQAFHREAYLARLLCAEKSMRIGTDGVQLLGGHGFTKEHPVERWYRDLRAT 425
+NAA + EAG F +A +A+L C+ + + + + +LGG GFTKE P E+++RD +
Sbjct 330 YNAARIKEAGLPFVFQASMAKLHCSRVAEKAASACISMLGGVGFTKEFPAEKFFRDSKVG 389
Query 426 AI 427
I
Sbjct 390 QI 391
>P52042 Acyl-CoA dehydrogenase, short-chain specific [Clostridium
acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG
5710 / VKM B-1787)]
Length=379
Score = 140 bits (354), Expect = 5e-41
Identities = 108/366 (30%), Positives = 178/366 (49%), Gaps = 23/366 (6%)
Query 79 DLSLTEEQTMTREAMSRFAQDVLMQIAHDADHHARFPEELWQYLEDLGLNYYALPESLGG 138
D +LT EQ + R+ + FA++ + IA + D RFP E + + G+ + GG
Sbjct 2 DFNLTREQELVRQMVREFAENEVKPIAAEIDETERFPMENVKKMGQYGMMGIPFSKEYGG 61
Query 139 VASEQNIVSNILIAEDLAQ----GDFSLSAGLLSTFSVINALTRWGSESTQSKYLTAFSE 194
+ ++S I+ E+L++ LSA S+IN G+E + KYL ++
Sbjct 62 AGGD--VLSYIIAVEELSKVCGTTGVILSAHTSLCASLIN---EHGTEEQKQKYLVPLAK 116
Query 195 DPNLKATFATQENTPAFNPFKLKTQATLQNNHYFLSGEKTLVILGESADLILVTAMLDGQ 254
+ A T+ N + + +T A L+ +HY ++G K + G AD ++ AM D
Sbjct 117 GEKIGAYGLTEPNAGTDSGAQ-QTVAVLEGDHYVINGSKIFITNGGVADTFVIFAMTDRT 175
Query 255 P-----EVFIVERD-PTISI-KSAPAMGLKAAQTMSLYFDHTPAVLLGDNDFDYSAF--- 304
FI+E+ SI K +G++A+ T L F+ + + F
Sbjct 176 KGTKGISAFIIEKGFKGFSIGKVEQKLGIRASSTTELVFEDMIVPVENMIGKEGKGFPIA 235
Query 305 ---IDLGSLMWCAMAVGTCEAVKSYCIAYANDRTAFGEPISHRQSVAFMIADMAIEIDAM 361
+D G + A A+G E + AY +R FG + Q +A+M+ADM + I++
Sbjct 236 MKTLDGGRIGIAAQALGIAEGAFNEARAYMKERKQFGRSLDKFQGLAWMMADMDVAIESA 295
Query 362 RMLIWNAASLAEAGQAFHREAYLARLLCAEKSMRIGTDGVQLLGGHGFTKEHPVERWYRD 421
R L++ AA L +AG + +A A+L A +M + T VQL GG+G+TK++PVER RD
Sbjct 296 RYLVYKAAYLKQAGLPYTVDAARAKLHAANVAMDVTTKAVQLFGGYGYTKDYPVERMMRD 355
Query 422 LRATAI 427
+ T I
Sbjct 356 AKITEI 361
>P45954 Short/branched chain specific acyl-CoA dehydrogenase,
mitochondrial [Homo sapiens]
Length=432
Score = 140 bits (354), Expect = 1e-40
Identities = 103/363 (28%), Positives = 187/363 (52%), Gaps = 22/363 (6%)
Query 81 SLTEEQTMTREAMSRFAQDVLMQIAHDADHHARFPEELWQYLEDLGLNYYALPESLGGVA 140
+ T+E+ M + ++ +FAQ+ + + D +++ + + Q L GL + GG
Sbjct 56 TFTDEEMMIKSSVKKFAQEQIAPLVSTMDENSKMEKSVIQGLFQQGLMGIEVDPEYGGTG 115
Query 141 SEQNIVSNILIAEDLAQGDFSLSAGLLSTFSVINALTR-WGSESTQSKYLTAFSEDPNLK 199
+ + +S +L+ E+LA+ D S++ ++IN L R G+E ++ YL + +
Sbjct 116 A--SFLSTVLVIEELAKVDASVAVFCEIQNTLINTLIRKHGTEEQKATYLPQLTTEK--V 171
Query 200 ATFATQENTPAFNPFKLKTQATLQNNHYFLSGEKTLVILGESADLILVTAMLDGQPEV-- 257
+F E + F LKT+A + ++Y L+G K + E A L LV A +D P +
Sbjct 172 GSFCLSEAGAGSDSFALKTRADKEGDYYVLNGSKMWISSAEHAGLFLVMANVD--PTIGY 229
Query 258 -----FIVERD-PTISI-KSAPAMGLKAAQTMSLYFDHTP---AVLLGDNDFDYSAFI-- 305
F+V+RD P + I K +GL+A+ T L F++ A +LG Y I
Sbjct 230 KGITSFLVDRDTPGLHIGKPENKLGLRASSTCPLTFENVKVPEANILGQIGHGYKYAIGS 289
Query 306 -DLGSLMWCAMAVGTCEAVKSYCIAYANDRTAFGEPISHRQSVAFMIADMAIEIDAMRML 364
+ G + A +G + Y I Y +R FG+ + Q + +A +A +++A R+L
Sbjct 290 LNEGRIGIAAQMLGLAQGCFDYTIPYIKERIQFGKRLFDFQGLQHQVAHVATQLEAARLL 349
Query 365 IWNAASLAEAGQAFHREAYLARLLCAEKSMRIGTDGVQLLGGHGFTKEHPVERWYRDLRA 424
+NAA L EAG+ F +EA +A+ +E + + + ++ +GG G+TK++PVE+++RD +
Sbjct 350 TYNAARLLEAGKPFIKEASMAKYYASEIAGQTTSKCIEWMGGVGYTKDYPVEKYFRDAKI 409
Query 425 TAI 427
I
Sbjct 410 GTI 412
>Q5RF40 Short/branched chain specific acyl-CoA dehydrogenase,
mitochondrial [Pongo abelii]
Length=432
Score = 139 bits (350), Expect = 4e-40
Identities = 102/363 (28%), Positives = 185/363 (51%), Gaps = 22/363 (6%)
Query 81 SLTEEQTMTREAMSRFAQDVLMQIAHDADHHARFPEELWQYLEDLGLNYYALPESLGGVA 140
+ T+E+ M + ++ +FAQ+ + + D +++ + + Q L GL + GG
Sbjct 56 TFTDEEMMIKSSVKKFAQEQIAPLVSTMDENSKMEKSVIQGLFQQGLMGIEVDPEYGGTG 115
Query 141 SEQNIVSNILIAEDLAQGDFSLSAGLLSTFSVINALTR-WGSESTQSKYLTAFSEDPNLK 199
+ + +S +L+ E+LA+ D S++ ++IN L R G+E + YL + +
Sbjct 116 A--SFLSTVLVIEELAKVDASVAVFCEIQNTLINTLIRKHGTEEQKGTYLPQLTTEK--V 171
Query 200 ATFATQENTPAFNPFKLKTQATLQNNHYFLSGEKTLVILGESADLILVTAMLDGQPEV-- 257
+F E + F LKT+A + ++Y L+G K + E A L LV A +D P +
Sbjct 172 GSFCLSEAGAGSDSFALKTRADKEGDYYVLNGSKMWISSAEHAGLFLVMANVD--PTIGY 229
Query 258 -----FIVERD-PTISI-KSAPAMGLKAAQTMSLYFDHTPAV---LLGDNDFDYSAFI-- 305
F+V+RD P + I K +GL+A+ T L F++ +LG Y I
Sbjct 230 KGITSFLVDRDTPGLHIGKPENKLGLRASSTCPLTFENVKVPETNILGQIGHGYKYAIGS 289
Query 306 -DLGSLMWCAMAVGTCEAVKSYCIAYANDRTAFGEPISHRQSVAFMIADMAIEIDAMRML 364
+ G + A +G + Y I Y +R FG+ + Q + +A +A +++A R+L
Sbjct 290 LNEGRIGIAAQMLGLAQGCFDYTIPYIKERIQFGKRLFDFQGLQHQVAHVATQLEAARLL 349
Query 365 IWNAASLAEAGQAFHREAYLARLLCAEKSMRIGTDGVQLLGGHGFTKEHPVERWYRDLRA 424
+NAA L EAG+ F +EA +A+ +E + + + ++ +GG G+TK++PVE+++RD +
Sbjct 350 TYNAARLLEAGKPFIKEASMAKYYASEIAGQTTSKCIEWMGGVGYTKDYPVEKYFRDAKI 409
Query 425 TAI 427
I
Sbjct 410 GTI 412
>Q2LQN9 Cyclohex-1-ene-1-carbonyl-CoA dehydrogenase [Syntrophus
aciditrophicus (strain SB)]
Length=414
Score = 135 bits (341), Expect = 6e-39
Identities = 104/392 (27%), Positives = 189/392 (48%), Gaps = 18/392 (5%)
Query 50 FKAISTAQKTFKTSSIDHQRLPKQNKSIFDLSLTEEQTMTREAMSRFAQDVLMQIAHDAD 109
F A+S ++ ++ + + ++ ++ +L TEEQ + E + A + A + D
Sbjct 7 FNALSLQGRSVMSNQSNDTTITQRRDTMNEL--TEEQKLLMEMVRNLAVREIAPRAIEID 64
Query 110 HHARFPEELWQYLEDLGLNYYALPESLGGVASEQNIVSNILIAEDLAQGDFSLSAGLLST 169
+ FP DLGL +P GG + I + ++ E++ + S + LL+
Sbjct 65 ENHSFPVHARDLFADLGLLSPLVPVEYGGTGMD--ITTFAMVLEEIGKVCASTALMLLAQ 122
Query 170 FSVINALTRWGSESTQSKYLTAFSEDPNLKATFATQENTPAFNPFKLKTQATLQNNHYFL 229
+ ++ GS + + KYL F E L FA E + +KT+A + + Y +
Sbjct 123 ADGMLSIILDGSPALKEKYLPRFGEKSTLMTAFAATEPGAGSDLLAMKTRAVKKGDKYVI 182
Query 230 SGEKTLVILGESADLILVTAMLDGQP-----EVFIVERDPTISI--KSAPAMGLKAAQTM 282
+G+K + G AD++ V A D F+VER I + MG++
Sbjct 183 NGQKCFITNGSVADILTVWAYTDPSKGAKGMSTFVVERGTPGLIYGHNEKKMGMRGCPNS 242
Query 283 SLYFD--HTPAV-LLGDNDFDYSAFIDLGSL--MWCA-MAVGTCEAVKSYCIAYANDRTA 336
L+F+ PA L+G+ ++ + S+ ++CA AVG + + + +R
Sbjct 243 ELFFEDLEVPAENLVGEEGKGFAYLMGALSINRVFCASQAVGIAQGALERAMQHTREREQ 302
Query 337 FGEPISHRQSVAFMIADMAIEIDAMRMLIWNAASLAEA-GQAFHREAYLARLLCAEKSMR 395
FG+PI+H + FMIADMA E++A R+L+ A +L +A + +A+ ++ +M+
Sbjct 303 FGKPIAHLTPIQFMIADMATEVEAARLLVRKATTLLDAKDKRGPLIGGMAKTFASDTAMK 362
Query 396 IGTDGVQLLGGHGFTKEHPVERWYRDLRATAI 427
+ TD VQ++GG G+ +E+ VER R+ + T I
Sbjct 363 VTTDAVQVMGGSGYMQEYQVERMMREAKLTQI 394
>Q3ZBF6 Short-chain specific acyl-CoA dehydrogenase, mitochondrial
[Bos taurus]
Length=412
Score = 135 bits (340), Expect = 8e-39
Identities = 98/364 (27%), Positives = 173/364 (48%), Gaps = 21/364 (6%)
Query 80 LSLTEEQTMTREAMSRFAQDVLMQIAHDADHHARFPEELWQYLEDLGLNYYALPESLGGV 139
+ L E M R+ FA+ L IA D RFP + + +LGL +PE L G
Sbjct 32 VELPETHQMLRQTCRDFAEKELFPIAAQVDKEHRFPAAQVKKMGELGLMAMNVPEELSGA 91
Query 140 ASEQNIVSNILIAEDLAQGDFSLSAGLLSTFS---VINALTRWGSESTQSKYLTAFSEDP 196
+ S + E++++G S G++ + + + + ++G++ + +++ F+
Sbjct 92 GLDYLAYS--IAMEEISRG--CASTGVIMSVNNSLYLGPILKFGTKEQKQQWVAPFTSGD 147
Query 197 NLKATFATQENTPAFNPFKLKTQATLQNNHYFLSGEKTLVILGESADLILVTAMLD---- 252
+ FA E + T A + + LSG K + A ++V A D
Sbjct 148 KI-GCFALSEPGNGSDAGAAATTARADGDSWVLSGTKAWITNAWEASAVVVFASTDRSLH 206
Query 253 --GQPEVFIVERDPTISI-KSAPAMGLKAAQTMSLYFDHTPAV---LLGDNDFDYSAF-- 304
G + P +++ K +G++A+ T +L F+ LLG+ +
Sbjct 207 NKGISAFLVPMPTPGLTLGKKEDKLGIRASSTANLIFEDRRIPKDSLLGEPGLGFKIAMQ 266
Query 305 -IDLGSLMWCAMAVGTCEAVKSYCIAYANDRTAFGEPISHRQSVAFMIADMAIEIDAMRM 363
+D G + + A+G +A + YA +R+AFG P++ Q++ F +ADMA+ +++ R+
Sbjct 267 TLDTGRIGIASQALGIAQAALDCAVTYAENRSAFGAPLTKLQAIQFKLADMALALESARL 326
Query 364 LIWNAASLAEAGQAFHREAYLARLLCAEKSMRIGTDGVQLLGGHGFTKEHPVERWYRDLR 423
L W AA L + + F +EA +A+L +E + I +Q+LGG G+ KE P ER YRD R
Sbjct 327 LTWRAAMLKDNKKPFTKEAAMAKLAASEAATAITHQAMQILGGMGYVKEMPAERHYRDAR 386
Query 424 ATAI 427
T I
Sbjct 387 ITEI 390
>P70584 Short/branched chain specific acyl-CoA dehydrogenase,
mitochondrial [Rattus norvegicus]
Length=432
Score = 134 bits (336), Expect = 4e-38
Identities = 101/361 (28%), Positives = 181/361 (50%), Gaps = 18/361 (5%)
Query 81 SLTEEQTMTREAMSRFAQDVLMQIAHDADHHARFPEELWQYLEDLGLNYYALPESLGGVA 140
+ T+E M ++A+ +FAQ+ + + D +++ + + Q L G+ + GG
Sbjct 56 TFTDEDIMMQKAVKKFAQEQIAPLVSTMDENSKMEKSVIQGLFQQGMMGIEVEAKYGG-- 113
Query 141 SEQNIVSNILIAEDLAQGDFSLSAGLLSTFSVINALTR-WGSESTQSKYLTAFSEDPNLK 199
+E + + ++L+ E+LA+ D S++ +VIN L R G+E ++ YL +
Sbjct 114 TEASFLCSVLVIEELAKVDASVALLCDIQNTVINKLFRKHGTEEQKATYLPKLVTEK--L 171
Query 200 ATFATQENTPAFNPFKLKTQATLQNNHYFLSGEKTLVILGESADLILVTAMLDGQP---- 255
+F E + F LKT+A N+Y ++G K + E A+L LV A +D
Sbjct 172 GSFCLSEAGAGSDSFALKTRADKSGNYYVINGSKMWISNAEHAELFLVFANVDPPSGYRG 231
Query 256 -EVFIVERDPT-ISI-KSAPAMGLKAAQTMSLYFDHTPAV---LLGDNDFDYSAFI---D 306
F+V+RD I + MG++A+ T L F++ +LG Y I +
Sbjct 232 ITCFLVDRDTEGFQIGRRENKMGIRASSTCQLTFENVKVPETSVLGKIGHGYKYAIGSLN 291
Query 307 LGSLMWCAMAVGTCEAVKSYCIAYANDRTAFGEPISHRQSVAFMIADMAIEIDAMRMLIW 366
G + A +G + Y I Y +R FG+ I Q + +A +A +++A R+L +
Sbjct 292 EGRIGIAAQMLGLAQGCFDYTIPYIKERMQFGKRIFDFQGLQHQVAHVATQLEAARLLTY 351
Query 367 NAASLAEAGQAFHREAYLARLLCAEKSMRIGTDGVQLLGGHGFTKEHPVERWYRDLRATA 426
NAA L EAG+ F +EA +A+ +E + + ++ +GG G+TK++PVE+++RD +
Sbjct 352 NAARLVEAGRPFIKEASMAKYYASEVAGLTTSKCIEWMGGVGYTKDYPVEKFFRDAKIGT 411
Query 427 I 427
I
Sbjct 412 I 412
Lambda K H a alpha
0.321 0.133 0.385 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 2019710
Database: d5662047d1bae898c9bcfd30e1b0ecf4.SwissProt.fasta
Posted date: Jun 2, 2024 3:50 AM
Number of letters in database: 5,996
Number of sequences in database: 15
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
