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Prior-Knowledge Description Expectation Prediction Conclusion Leaf Statistics
ULS00345 formate from formaldehyde (H(4)MPT route) None - {{∅}} None - {{∅}} Unexplained
UPA00562 formaldehyde degradation~Degradation of formaldehyde, a toxic compound for all organisms from bacteria to humans due to its reactivity with biological macromolecules (nonspecific reactivity with proteins and nucleic acids). Organisms that grow aerobically on single-carbon compounds such as methanol and methane face a special challenge in this regard because formaldehyde is a central metabolic intermediate during methylotrophic growth. . None - {{∅}} None - {{∅}} Unexplained
UER00623 formate from formaldehyde (glutathione route): step 3/3~1 H(2)O + 1 S-formylglutathione => 1 formate + 1 glutathione. None - {{∅}} None - {{∅}} Unexplained
ULS00297 formate from formaldehyde (glutathione route) None - {{∅}} None - {{∅}} Unexplained
VariantPath-1-UER00622 None - {{∅}} None - {{∅}} Unexplained
UER00622 formate from formaldehyde (glutathione route): step 2/3~S-(hydroxymethyl)glutathione + [NAD(+) or NADP(+)] => H(+) + S-formylglutathione + [NADH or NADPH]. None - {{∅}} None - {{∅}} Unexplained
VariantPath-2-UPA00562 None - {{∅}} None - {{∅}} Unexplained
VariantPath-2-UER00622 None - {{∅}} None - {{∅}} Unexplained
UER00621 formate from formaldehyde (glutathione route): step 1/3~1 formaldehyde + 1 glutathione => 1 S-(hydroxymethyl)glutathione. None - {{∅}} None - {{∅}} Unexplained
UER00704 formate from formaldehyde (H(4)MPT route): step 4/5~1 N(5)-formyl-5,6,7,8-tetrahydromethanopterin + 1 methanofuran => 1 5,6,7,8-tetrahydromethanopterin + 1 N-formylmethanofuran. None - {{∅}} None - {{∅}} Unexplained
VariantPath-1-UPA00562 None - {{∅}} None - {{∅}} Unexplained
UER00701 formate from formaldehyde (H(4)MPT route): step 1/5~1 5,6,7,8-tetrahydromethanopterin + 1 formaldehyde => 1 5,10-methylene-5,6,7,8-tetrahydromethanopterin + 1 H(2)O. None - {{∅}} None - {{∅}} Unexplained
UER00971 None~1 NAD(+) + 1 S-(hydroxymethyl)glutathione => 1 H(+) + 1 NADH + 1 S-formylglutathione. None - {{∅}} None - {{∅}} Unexplained
UER00702 formate from formaldehyde (H(4)MPT route): step 2/5~1 5,10-methylene-5,6,7,8-tetrahydromethanopterin + 1 NADP(+) => 1 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + 1 NADPH. None - {{∅}} None - {{∅}} Unexplained
UER00972 None~1 NADP(+) + 1 S-(hydroxymethyl)glutathione => 1 H(+) + 1 NADPH + 1 S-formylglutathione. None - {{∅}} None - {{∅}} Unexplained
UER00703 formate from formaldehyde (H(4)MPT route): step 3/5~1 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + 1 H(2)O => 1 H(+) + 1 N(5)-formyl-5,6,7,8-tetrahydromethanopterin. None - {{∅}} None - {{∅}} Unexplained
UER00705 formate from formaldehyde (H(4)MPT route): step 5/5~1 H(2)O + 1 N-formylmethanofuran => 1 formate + 1 methanofuran. None - {{∅}} None - {{∅}} Unexplained