UER00877 |
L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 4/6~1 2-hydroxy-5-(methylsulfanyl)-3-oxopent-1-enyl phosphate + 1 H(2)O => 1 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + 1 phosphate. |
None - {{∅}} |
None - {{∅}} |
Unexplained |
|
UER00872 |
S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'-thioadenosine (hydrolase route): step 2/2~1 5-methylthio-alpha-D-ribose + 1 ATP => 1 ADP + 1 S-methyl-5-thio-alpha-D-ribose 1-phosphate. |
None - {{∅}} |
None - {{∅}} |
Unexplained |
|
UER00874 |
L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 1/6~1 S-methyl-5-thio-alpha-D-ribose 1-phosphate => 1 S-methyl-5-thio-D-ribulose 1-phosphate. |
None - {{∅}} |
None - {{∅}} |
Unexplained |
|
VariantPath-1-UPA00904 |
|
None - {{∅}} |
None - {{∅},{t}} |
Unexplained |
|
ULS00433 |
S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'-thioadenosine (phosphorylase route) |
None - {{∅}} |
None - {{∅}} |
Unexplained |
|
UER00873 |
S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'-thioadenosine (phosphorylase route): step 1/1~1 S-methyl-5'-thioadenosine + 1 phosphate => 1 S-methyl-5-thio-alpha-D-ribose 1-phosphate + 1 adenine. |
None - {{∅}} |
None - {{∅}} |
Unexplained |
|
UER00875 |
L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6~1 S-methyl-5-thio-D-ribulose 1-phosphate => 1 5-(methylthio)-2,3-dioxopentyl phosphate + 1 H(2)O. |
None - {{∅}} |
None - {{∅}} |
Unexplained |
|
UER00879 |
L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 6/6~1 4-methylthio-2-oxobutanoate + 1 L-glutamate => 1 2-oxoglutarate + 1 L-methionine. |
None - {{∅}} |
None - {{∅}} |
Unexplained |
|
VariantPath-2-UPA00904 |
|
None - {{∅}} |
None - {{∅}} |
Unexplained |
|
UPA00904 |
L-methionine biosynthesis via salvage pathway~The methionine salvage pathway (MSP) is an important metabolic pathway in maintaining the amount of L-methionine as the amount of methionine in cells is typically limiting and its de novo biosynthesis is energetically expensive. Therefore, L-methionine is salvaged from S-methyl-5'-thioadenosine (MTA), the end-product of spermidine biosynthesis. |
None - {{∅}} |
None - {{∅},{t}} |
Unexplained |
|
UER00876 |
L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 3/6~1 5-(methylthio)-2,3-dioxopentyl phosphate => 1 2-hydroxy-5-(methylsulfanyl)-3-oxopent-1-enyl phosphate. |
None - {{∅}} |
None - {{∅}} |
Unexplained |
|
ULS00432 |
S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'-thioadenosine (hydrolase route) |
None - {{∅}} |
None - {{∅},{t}} |
Unexplained |
|
ULS00434 |
L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate |
None - {{∅}} |
None - {{∅}} |
Unexplained |
|
UER00871 |
S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'-thioadenosine (hydrolase route): step 1/2~1 H(2)O + 1 S-methyl-5'-thioadenosine => 1 5-methylthio-alpha-D-ribose + 1 adenine. |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
UER00878 |
L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 5/6~1 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + 1 O(2) => 1 4-methylthio-2-oxobutanoate + 1 formate. |
None - {{∅}} |
None - {{∅}} |
Unexplained |
|