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Prior-Knowledge Description Expectation Prediction Conclusion Leaf Statistics
VariantPath-1-UER00856 None - {{∅}} None - {{∅}} Unexplained
UER00993 None~1 H(+) + 1 NADH + 1 dihydrobiopterin => 1 NAD(+) + 1 tetrahydrobiopterin. None - {{∅}} None - {{∅}} Unexplained
UER00819 tetrahydrobiopterin from 7,8-dihydroneopterin triphosphate: step 1/3~1 7,8-dihydroneopterin triphosphate => 1 6-pyruvoyl-tetrahydropterin + 1 triphosphate. None - {{∅}} None - {{∅}} Unexplained
UCR01812 2 NADP(+) + tetrahydrobiopterin = 2 H(+) + 2 NADPH + biopterin None - {{∅}} None - {{∅}} Unexplained
VariantPath-2-UER00856 None - {{∅}} None - {{∅}} Unexplained
VariantPath-3-UPA00849 None - {{∅}} None - {{∅}} Unexplained
UER00994 None~1 H(+) + 1 NADPH + 1 dihydrobiopterin => 1 NADP(+) + 1 tetrahydrobiopterin. None - {{∅}} None - {{∅}} Unexplained
UCR04286 7,8-dihydroneopterin triphosphate = 6-pyruvoyl-tetrahydropterin + triphosphate None - {{∅}} None - {{∅}} Unexplained
UCR01793 H(+) + NADH + dihydrobiopterin = NAD(+) + tetrahydrobiopterin None - {{∅}} None - {{∅}} Unexplained
UER00822 tetrahydrobiopterin from biopterin: step 1/1~2 H(+) + 2 NADPH + 1 biopterin => 2 NADP(+) + 1 tetrahydrobiopterin. None - {{∅}} None - {{∅}} Unexplained
ULS00413 tetrahydrobiopterin from 7,8-dihydroneopterin triphosphate None - {{∅}} None - {{∅}} Unexplained
UER00821 tetrahydrobiopterin from 7,8-dihydroneopterin triphosphate: step 3/3~1 6-lactoyl-5,6,7,8-tetrahydropterin + 1 H(+) + 1 NADPH => 1 NADP(+) + 1 tetrahydrobiopterin. None - {{∅}} None - {{∅}} Unexplained
UCR01794 H(+) + NADPH + dihydrobiopterin = NADP(+) + tetrahydrobiopterin None - {{∅}} None - {{∅}} Unexplained
UCR01813 NADP(+) + tetrahydrobiopterin = 6-lactoyl-5,6,7,8-tetrahydropterin + H(+) + NADPH None - {{∅}} None - {{∅}} Unexplained
ULS00423 tetrahydrobiopterin from dihydrobiopterin None - {{∅}} None - {{∅}} Unexplained
UER00820 tetrahydrobiopterin from 7,8-dihydroneopterin triphosphate: step 2/3~1 6-pyruvoyl-tetrahydropterin + 1 H(+) + 1 NADPH => 1 6-lactoyl-5,6,7,8-tetrahydropterin + 1 NADP(+). None - {{∅}} None - {{∅}} Unexplained
UER00856 tetrahydrobiopterin from dihydrobiopterin: step 1/1~H(+) + dihydrobiopterin + [NADH or NADPH] => tetrahydrobiopterin + [NAD(+) or NADP(+)]. None - {{∅}} None - {{∅}} Unexplained
VariantPath-1-UPA00849 None - {{∅}} None - {{∅}} Unexplained
UPA00849 tetrahydrobiopterin biosynthesis~Biosynthesis of tetrahydrobiopterin (sapropterin, BH4, H4-biopterin). Tetrahydrobiopterin is an essential cofactor of a set of enzymes that are of central metabolic importance, i.e. the hydroxylases of the three aromatic amino acids phenylalanine, tyrosine, and tryptophan, of ether lipid oxidase, and of the three nitric oxide synthase (NOS) isoenzymes. Tetrahydrobiopterin is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylases; phenylalanine-4-hydroxylase, tyrosine-3-hydroxylase and tryptophan-5-hydroxylase. Tetrahydrobiopterin is also essential for the synthesis of nitric oxide by nitric oxide synthase (NOS). None - {{∅}} None - {{∅}} Unexplained
ULS00414 tetrahydrobiopterin from biopterin None - {{∅}} None - {{∅}} Unexplained
UCR04285 6-lactoyl-5,6,7,8-tetrahydropterin + NADP(+) = 6-pyruvoyl-tetrahydropterin + H(+) + NADPH None - {{∅}} None - {{∅}} Unexplained
VariantPath-2-UPA00849 None - {{∅}} None - {{∅}} Unexplained