Component_35615 |
dihydroxy-acid dehydratase |
True - {{t}} |
False - {{f}} |
Unexpected absence |
|
Evidence_47969 |
TIGR02079 HMM |
True - {{t}} |
False - {{f}} |
Unexpected absence |
|
Evidence_47965 |
TIGR01122 HMM |
None - {{∅}} |
False - {{f}} |
Unconfirmed absence |
|
Component_35612 |
acetohydroxyacid synthase, large subunit |
True - {{t}} |
False - {{f}} |
Unexpected absence |
|
GenProp0162 |
isoleucine biosynthesis from threonine and pyruvate~The branched amino acid isoleucine is biosynthesized from the central intermediary metabolite pyruvate and the amino acid threonine via a five step pathway. Four enzymes in this pathway are common to the pathways for the biosynthesis of leucine and valine, although specialized versions of these enzymes may exist in certain species which have a narrowed substrate range or amino acid-specific regulatory mechanisms. Unlike those other two pathways in which two molecules of pyruvate are condensed, here threonine is converted first to 2-oxobutyrate and then condensed with pyruvate. Thus, the enzymes common to the pathways are acting on distinct substrates. 2-oxobutyrate for this pathway may also be generated by a separate path from glutamate via mesaconate in certain organisms. The penultimate intermediate in this pathway, 2-oxo-3-methylvalerate may also be incorporated into branched-chain fatty acids |
True - {{t}} |
False - {{f}} |
Unexpected absence |
|
Component_35614 |
ketol-acid reductoisomerase |
True - {{t}} |
False - {{f}} |
Unexpected absence |
|
Evidence_47963 |
TIGR00465 HMM |
True - {{t}} |
False - {{f}} |
Unexpected absence |
|
Evidence_47959 |
TIGR01127 HMM |
True - {{t}} |
False - {{f}} |
Unexpected absence |
|
Evidence_47966 |
TIGR01123 HMM |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
Component_35616 |
branched-chain amino acid aminotransferase |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
Evidence_47961 |
TIGR01124 HMM |
True - {{t}} |
False - {{f}} |
Unexpected absence |
|
Component_35611 |
threonine dehydratase |
True - {{t}} |
False - {{f}} |
Unexpected absence |
|
Evidence_47962 |
TIGR00119 HMM |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
Evidence_47964 |
TIGR00110 HMM |
True - {{t}} |
False - {{f}} |
Unexpected absence |
|
Evidence_47960 |
TIGR00118 HMM |
True - {{t}} |
False - {{f}} |
Unexpected absence |
|
Component_35613 |
acetohydroxyacid synthase, small subunit |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|