| UCR04138 | 3-methylcrotonyl-CoA + ATP + bicarbonate = 3-methylglutaconyl-CoA + ADP + phosphate | Both - {{t,f}} | True - {{t}} | Ambiguous presence |  | 
                
                    | ULS00425 | 4-methyl-2-oxopentanoate from L-leucine (dehydrogenase route) | Both - {{t,f}} | True - {{t}} | Ambiguous presence |  | 
                
                    | UER00861 | (S)-3-hydroxy-3-methylglutaryl-CoA from 3-isovaleryl-CoA: step 2/3~1 3-methylcrotonyl-CoA + 1 ATP + 1 bicarbonate => 1 3-methylglutaconyl-CoA + 1 ADP + 1 phosphate. | Both - {{t,f}} | True - {{t}} | Ambiguous presence |  | 
                
                    | VariantPath-1-UPA00363 |  | Both - {{t,f}} | None - {{∅},{t}} | Ambiguous |  | 
                
                    | ULS00424 | 4-methyl-2-oxopentanoate from L-leucine (aminotransferase route) | Both - {{t,f}} | True - {{t}} | Ambiguous presence |  | 
                
                    | UCR01090 | 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate | Both - {{t},{t,f}} | True - {{t}} | Ambiguous presence |  | 
                
                    | UPA00363 | L-leucine degradation~Degradation of L-leucine, one of the three main branched chain amino-acids (BCAAs), along with L-valine and L-isoleucine. In plants, branched-chain amino-acids are synthesized in chloroplasts, whereas the degradation takes place in mitochondria. | Both - {{t,f}} | None - {{∅},{t}} | Ambiguous |  | 
                
                    | VariantPath-2-UPA00363 |  | Both - {{t,f}} | None - {{∅},{t}} | Ambiguous |  | 
                
                    | UCR04095 | 3-isovaleryl-CoA + FAD = 3-methylcrotonyl-CoA + FADH2 | Both - {{t,f}} | None - {{∅}} | Ambiguous |  | 
                
                    | UCR01088 | H(2)O + L-leucine + NAD(+) = 4-methyl-2-oxopentanoate + H(+) + NADH + NH(3) | Both - {{t,f}} | True - {{t}} | Ambiguous presence |  | 
                
                    | ULS00427 | (S)-3-hydroxy-3-methylglutaryl-CoA from 3-isovaleryl-CoA | Both - {{t,f}} | None - {{∅},{t}} | Ambiguous |  | 
                
                    | UER00860 | (S)-3-hydroxy-3-methylglutaryl-CoA from 3-isovaleryl-CoA: step 1/3~1 3-isovaleryl-CoA + 1 FAD => 1 3-methylcrotonyl-CoA + 1 FADH2. | Both - {{t,f}} | None - {{∅}} | Ambiguous |  | 
                
                    | UER00862 | (S)-3-hydroxy-3-methylglutaryl-CoA from 3-isovaleryl-CoA: step 3/3~1 3-methylglutaconyl-CoA + 1 H(2)O => 1 (S)-3-hydroxy-3-methylglutaryl-CoA. | Both - {{t},{t,f}} | True - {{t}} | Ambiguous presence |  | 
                
                    | UCR02085 | (S)-3-hydroxy-3-methylglutaryl-CoA = 3-methylglutaconyl-CoA + H(2)O | Both - {{t},{t,f}} | True - {{t}} | Ambiguous presence |  | 
                
                    | UER00858 | 4-methyl-2-oxopentanoate from L-leucine (dehydrogenase route): step 1/1~1 H(2)O + 1 L-leucine + 1 NAD(+) => 1 4-methyl-2-oxopentanoate + 1 H(+) + 1 NADH + 1 NH(3). | Both - {{t,f}} | True - {{t}} | Ambiguous presence |  | 
                
                    | UER00859 | 3-isovaleryl-CoA from 4-methyl-2-oxopentanoate: step 1/1~1 4-methyl-2-oxopentanoate + 1 CoA + 1 NAD(+) => 1 3-isovaleryl-CoA + 1 CO(2) + 1 H(+) + 1 NADH. | Both - {{t,f}} | None - {{∅}} | Ambiguous |  | 
                
                    | UCR01651 | 4-methyl-2-oxopentanoate + CoA + NAD(+) = 3-isovaleryl-CoA + CO(2) + H(+) + NADH | Both - {{t,f}} | None - {{∅}} | Ambiguous |  | 
                
                    | UER00857 | 4-methyl-2-oxopentanoate from L-leucine (aminotransferase route): step 1/1~1 2-oxoglutarate + 1 L-leucine => 1 4-methyl-2-oxopentanoate + 1 L-glutamate. | Both - {{t,f}} | True - {{t}} | Ambiguous presence |  | 
                
                    | ULS00426 | 3-isovaleryl-CoA from 4-methyl-2-oxopentanoate | Both - {{t,f}} | None - {{∅}} | Ambiguous |  |