| MUER19 |
Meta-UER 19~1 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide + 1 L-glutamine => 1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + 1 D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + 1 L-glutamate. |
True - {{∅},{t}} |
True - {{t}} |
Confirmed presence |
|
| UER00012 |
L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9~1 L-glutamate + 1 imidazole-acetol phosphate => 1 2-oxoglutarate + 1 L-histidinol phosphate. |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
| ULS00005 |
L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate |
True - {{t}} |
None - {{∅},{t}} |
Missing |
|
| UCR04640 |
5-(5-phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide = 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
| UCR04035 |
1-(5-phospho-D-ribosyl)-ATP + H(2)O = 1-(5-phosphoribosyl)-5'-AMP + diphosphate |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
| UCR03243 |
2-oxoglutarate + L-histidinol phosphate = L-glutamate + imidazole-acetol phosphate |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
| UCR04558 |
5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + L-glutamate |
True - {{∅},{t}} |
True - {{t}} |
Confirmed presence |
|
| UCR01158 |
H(2)O + L-histidinol + 2 NAD(+) = 2 H(+) + L-histidine + 2 NADH |
True - {{t}} |
None - {{∅}} |
Missing |
|
| UER00008 |
L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9~1 1-(5-phosphoribosyl)-5'-AMP + 1 H(2)O => 1 5-(5-phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide. |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
| UCR01071 |
1-(5-phospho-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
| UER00011 |
L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9~1 D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate => 1 H(2)O + 1 imidazole-acetol phosphate. |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
| UCR03013 |
H(2)O + L-histidinol phosphate = L-histidinol + phosphate |
True - {{t}} |
None - {{∅}} |
Missing |
|
| UPA00031 |
L-histidine biosynthesis~Biosynthesis of L-histidine, (S)-alpha-Amino- 1H-imidazole-4-propionic acid, a weakly basic amino-acid in a nine- step pathway. Histidine biosynthetic pathway is present in microbes, fungi and plants. Histidine biosynthesis is unusual as a metabolic process utilizing the purine ring of ATP as a carbon and nitrogen source. Histidine biosynthesis pathway is connected to de novo purine biosynthesis pathway through imidazole glycerol phosphate synthase (IGPS) which catalyzes the fifth step and converts N-(5'-phosphoribulosys)-formimino-5-aminoimidazole-4-carboxamide ribonucleotide (PRFAR) to imidazole glycerol phosphate (ImGP) and 5'-(5-aminoimidazole-4-carboxamide) ribonucleotide (AICAR). AICAR is the entry point to the purine biosynthetic pathway. |
True - {{t}} |
None - {{∅},{t}} |
Missing |
|
| UER00014 |
L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 9/9~1 H(2)O + 1 L-histidinol + 2 NAD(+) => 2 H(+) + 1 L-histidine + 2 NADH. |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
| UER00013 |
L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 8/9~1 H(2)O + 1 L-histidinol phosphate => 1 L-histidinol + 1 phosphate. |
True - {{t}} |
None - {{∅}} |
Missing |
|
| UER00007 |
L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9~1 1-(5-phospho-D-ribosyl)-ATP + 1 H(2)O => 1 1-(5-phosphoribosyl)-5'-AMP + 1 diphosphate. |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
| UCR04037 |
1-(5-phosphoribosyl)-5'-AMP + H(2)O = 5-(5-phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
| UER00006 |
L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9~1 5-phospho-alpha-D-ribose 1-diphosphate + 1 ATP => 1 1-(5-phospho-D-ribosyl)-ATP + 1 diphosphate. |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
| UCR03457 |
D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = H(2)O + imidazole-acetol phosphate |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
| UER00009 |
L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9~1 5-(5-phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide => 1 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide. |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|