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Prior-Knowledge Description Expectation Prediction Conclusion Leaf Statistics
ULS00283 thiamine diphosphate from thiamine phosphate None - {{∅}} True - {{t}} Unconfirmed presence
UER00596 thiamine phosphate from thiamine: step 1/1~1 ATP + 1 thiamine => 1 ADP + 1 thiamine phosphate. None - {{∅}} None - {{∅}} Unexplained
UER00136 4-amino-2-methyl-5-diphosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole: step 1/3~1 5-amino-1-(5-phospho-D-ribosyl)imidazole => 1 4-amino-5-hydroxymethyl-2-methylpyrimidine. None - {{∅}} None - {{∅}} Unexplained
UER00141 thiamine phosphate from 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole: step 1/1~1 4-amino-2-methyl-5-diphosphomethylpyrimidine + 1 4-methyl-5-(2-phosphoethyl)-thiazole => 1 diphosphate + 1 thiamine phosphate. None - {{∅}} True - {{t}} Unconfirmed presence
UER00137 4-amino-2-methyl-5-diphosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole: step 2/3~1 4-amino-5-hydroxymethyl-2-methylpyrimidine + 1 ATP => 1 4-amino-2-methyl-5-phosphomethylpyrimidine + 1 ADP. None - {{∅}} None - {{∅}} Unexplained
ULS00060 thiamine phosphate from 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole None - {{∅}} True - {{t}} Unconfirmed presence
ULS00057 4-amino-2-methyl-5-diphosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole None - {{∅}} None - {{∅},{t}} Unexplained
UER00139 4-methyl-5-(2-phosphoethyl)-thiazole from 5-(2-hydroxyethyl)-4-methylthiazole: step 1/1~1 5-(2-hydroxyethyl)-4-methylthiazole + 1 ATP => 1 4-methyl-5-(2-phosphoethyl)-thiazole + 1 ADP. None - {{∅}} None - {{∅}} Unexplained
UER00140 4-methyl-5-(2-phosphoethyl)-thiazole from 1-deoxy-D-xylulose 5-phosphate: step 1/1~1 1-deoxy-D-xylulose 5-phosphate => 1 4-methyl-5-(2-phosphoethyl)-thiazole. None - {{∅}} None - {{∅}} Unexplained
UER00138 4-amino-2-methyl-5-diphosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole: step 3/3~1 4-amino-2-methyl-5-phosphomethylpyrimidine + 1 ATP => 1 4-amino-2-methyl-5-diphosphomethylpyrimidine + 1 ADP. None - {{∅}} True - {{t}} Unconfirmed presence
UER00142 thiamine diphosphate from thiamine phosphate: step 1/1~1 ATP + 1 thiamine phosphate => 1 ADP + 1 thiamine diphosphate. None - {{∅}} True - {{t}} Unconfirmed presence
ULS00284 thiamine phosphate from thiamine None - {{∅}} None - {{∅}} Unexplained
ULS00059 4-methyl-5-(2-phosphoethyl)-thiazole from 1-deoxy-D-xylulose 5-phosphate None - {{∅}} None - {{∅}} Unexplained
ULS00285 thiamine diphosphate from thiamine None - {{∅}} None - {{∅}} Unexplained
VariantPath-5-UPA00060 None - {{∅}} None - {{∅},{t}} Unexplained
UER00597 thiamine diphosphate from thiamine: step 1/1~1 ATP + 1 thiamine => 1 AMP + 1 thiamine diphosphate. None - {{∅}} None - {{∅}} Unexplained
VariantPath-2-UPA00060 None - {{∅}} None - {{∅},{t}} Unexplained
VariantPath-4-UPA00060 None - {{∅}} None - {{∅},{t}} Unexplained
ULS00058 4-methyl-5-(2-phosphoethyl)-thiazole from 5-(2-hydroxyethyl)-4-methylthiazole None - {{∅}} None - {{∅}} Unexplained
VariantPath-3-UPA00060 None - {{∅}} None - {{∅}} Unexplained
UPA00060 thiamine diphosphate biosynthesis~Biosynthesis of thiamin pyrophosphate (THI-PP, TPP), the active form of thiamine cofactor (vitamin B1). It has essential functions, for example in carbohydrate and branched-chain amino-acid metabolism. All organisms able to to produce THI-PP initially assemble THI-P by coupling 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole. THI-P is then converted to TPP. The two heterocyclic precursors of thiamine pyrophosphate are synthesized through independant pathways. WARNING: the DXP_MHETP_BIOS sub-pathway is temporary. It will be refined as soon as knowledge will be available. None - {{∅}} None - {{∅},{t}} Unexplained
VariantPath-1-UPA00060 None - {{∅}} None - {{∅},{t}} Unexplained