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Prior-Knowledge Description Expectation Prediction Conclusion Leaf Statistics
Evidence_82159 TIGR01819 HMM None - {{∅}} True - {{t}} Unconfirmed presence
Evidence_82164 TIGR01916 HMM None - {{∅}} True - {{t}} Unconfirmed presence
Component_60609 LPPG:Fo 2-phospho-L-lactate transferase None - {{∅}} True - {{t}} Unconfirmed presence
Evidence_82160 TIGR03552 HMM None - {{∅}} True - {{t}} Unconfirmed presence
GenProp0792 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) biosynthesis~7,8-didemethyl-8-hydroxy-5-deazariboflavin, or FO, is the chromophore of coenzyme F420. Several enzymatic steps convert FO to F420 (see GenProp0791). FO is also the chromophore of a cyanobacterial DNA photoreactivating enzyme. The two key enzymes of this pathway, encoded by CofG and CofH in Methanocaldococcus jannaschii, are encoded by fusion proteins in certain lineages. The fusion protein in Mycobacterium smegmatis is designated FbiC (F420 BIosynthesis C). The precursors are a pyrimidine intermediate from riboflavin biosynthesis and the 4-hydroxyphenylpyruvate precursor of tyrosine, so expressing FbiC in Escherichia coli is sufficient for FO biosynthesis. None - {{∅}} True - {{t}} Unconfirmed presence
Evidence_82162 TIGR03550 HMM None - {{∅}} True - {{t}} Unconfirmed presence
Evidence_82163 GenProp0792 GENPROP None - {{∅}} True - {{t}} Unconfirmed presence
Component_60614 F420-O:gamma-glutamyl ligase None - {{∅}} True - {{t}} Unconfirmed presence
Evidence_85833 TIGR04443 HMM None - {{∅}} None - {{∅}} Unexplained
Evidence_82161 TIGR03551 HMM None - {{∅}} True - {{t}} Unconfirmed presence
Component_60621 NADPH-dependent F420 reductase None - {{∅}} True - {{t}} Unconfirmed presence
Component_64057 coenzyme gamma-F420-2:alpha-L-glutamate ligase None - {{∅}} None - {{∅}} Unexplained
Evidence_82165 TIGR03553 HMM None - {{∅}} None - {{∅}} Unexplained
Component_60610 lactoylphosphate guanylyltransferase None - {{∅}} True - {{t}} Unconfirmed presence
Component_60613 FO biosynthesis None - {{∅}} True - {{t}} Unconfirmed presence
Component_60612 FO synthase, CofG subunit None - {{∅}} True - {{t}} Unconfirmed presence
GenProp0791 coenzyme F420 biosynthesis~The chromophore of coenzyme F420 is 7,8-didemethyl-8-hydroxy-5-deazaflavin, or FO, which is also used in a cyanobacterial DNA photoreactivating enzyme. Modification of FO to create coenzyme F420 includes the GTP-dependent addition of two glutamate residues in Methanococcus jannaschii and five or six in Mycobacterium bovis. CofF, which caps the gamma-glutamyl tail after two glutamates, occurs only the archaea. None - {{∅}} True - {{t}} Unconfirmed presence
Component_60611 FO synthase, CofH subunit None - {{∅}} True - {{t}} Unconfirmed presence
Evidence_82171 TIGR01915 HMM None - {{∅}} True - {{t}} Unconfirmed presence
Component_60615 F420 biosynthesis protein FbiB, C-terminal domain None - {{∅}} None - {{∅}} Unexplained