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Prior-Knowledge Description Expectation Prediction Conclusion Leaf Statistics
Evidence_63398 TIGR02303 HMM True - {{t}} True - {{t}} Confirmed presence
Evidence_63391 TIGR02297 HMM None - {{∅}} None - {{∅}} Unexplained
Component_50880 5-carboxymethyl-2-hydroxymuconate delta-isomerase (5.3.3.10) True - {{t}} True - {{t}} Confirmed presence
Evidence_63401 TIGR02309 HMM True - {{t}} None - {{∅}} Missing
Evidence_63390 TIGR02296 HMM True - {{t}} None - {{∅}} Missing
Component_50879 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase (1.2.1.60) True - {{t}} True - {{t}} Confirmed presence
Component_50887 succinate-semialdehyde dehydrogenase True - {{t}} True - {{t}} Confirmed presence
Component_50922 regulatory protein, HpaR None - {{∅}} True - {{t}} Unconfirmed presence
Evidence_63414 TIGR02311 HMM True - {{t}} True - {{t}} Confirmed presence
Evidence_63415 TIGR02312 HMM True - {{t}} True - {{t}} Confirmed presence
Component_50883 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase True - {{t}} True - {{t}} Confirmed presence
Evidence_63405 TIGR01780 HMM True - {{t}} True - {{t}} Confirmed presence
Component_50886 bifunctional decarboxylase/isomerase, C-terminal True - {{t}} True - {{t}} Confirmed presence
Evidence_63397 PF02962 HMM True - {{t}} True - {{t}} Confirmed presence
Evidence_63440 TIGR02332 HMM None - {{∅}} None - {{∅}} Unexplained
Component_50919 probable 4-hydroxyphenylacetate transporters None - {{∅}} None - {{∅}} Unexplained
Component_50877 4-hydroxyphenylacetate 3-monooxygenase, small subunit True - {{t}} None - {{∅}} Missing
Evidence_63393 TIGR02299 HMM True - {{t}} True - {{t}} Confirmed presence
Component_50881 bifunctional decarboxylase/isomerase, N-terminal True - {{t}} None - {{∅}} Missing
Evidence_63420 TIGR02313 HMM None - {{∅}} None - {{∅}} Unexplained
GenProp0231 4-hydroxyphenylacetate degradation~4-hydroxyphenylacetic acid, a degradation product of tyrosine via one of several routes, of phenylalanine via phenylacetate, and of environmental DDT is metabolized in this pathway to the common metabolites succinate and pyruvate via homoprotocatechuate. 4-hydroxyphenylacetic acid may also be found in the environment and transported into the cell. The genes encoding the components of this pathway are often organized into apparent operons which include regulatory elements as well as a variety of transport systems. A number of genomes show partial evidence of the pathway based on homologs of the well-characterized enzymes from other species. Often, promising candidates for the missing steps are found in the vicinity. These are suggestive of enzymes which have been adapted from ancestral sequences having a different function. Of course, the possibility exists that it is the entire pathway that has been modified in these species and it is other structurally related compounds that are being metabolized instead of 4-hydroxyphenylacetic acid. True - {{t}} None - {{∅},{t}} Missing
Component_50882 2-oxo-hepta-3-ene-1,7-dioate hydratase True - {{t}} True - {{t}} Confirmed presence
Evidence_63392 TIGR02298 HMM True - {{t}} None - {{∅}} Missing
Component_50885 4-hydroxyphenylacetate 3-monooxygenase, large subunit True - {{t}} None - {{∅}} Missing
Evidence_63400 TIGR02305 HMM True - {{t}} None - {{∅}} Missing
Evidence_63446 TIGR02337 HMM None - {{∅}} True - {{t}} Unconfirmed presence
Component_50884 regulatory protein, HpaA None - {{∅}} None - {{∅}} Unexplained
Component_50878 3,4-dihydroxyphenylacetate 2,3-dioxygenase (1.13.11.15) True - {{t}} None - {{∅}} Missing
Evidence_63386 TIGR02295 HMM True - {{t}} None - {{∅}} Missing
Evidence_63402 TIGR02310 HMM True - {{t}} None - {{∅}} Missing