| UCR00342 |
(S)-malate + NAD(+) = H(+) + NADH + oxaloacetate |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
| ULS00352 |
isocitrate from oxaloacetate |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UER00719 |
(S)-malate from isocitrate: step 1/2~1 isocitrate => 1 glyoxylate + 1 succinate. |
None - {{∅}} |
None - {{∅}} |
Unexplained |
|
| UCR00479 |
isocitrate = glyoxylate + succinate |
None - {{∅}} |
None - {{∅}} |
Unexplained |
|
| UCR01325 |
citrate = H(2)O + cis-aconitate |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
| ULS00354 |
oxaloacetate from (S)-malate |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UER00718 |
isocitrate from oxaloacetate: step 2/2~1 citrate => 1 isocitrate. |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
| UCR01900 |
isocitrate = H(2)O + cis-aconitate |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
| UER00717 |
isocitrate from oxaloacetate: step 1/2~1 H(2)O + 1 acetyl-CoA + 1 oxaloacetate => 1 CoA + 1 citrate. |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
| UCR00472 |
(S)-malate + CoA = H(2)O + acetyl-CoA + glyoxylate |
None - {{∅}} |
None - {{∅}} |
Unexplained |
|
| UPA00703 |
glyoxylate cycle~Glyoxylate cycle is a metabolic pathway occurring in plants, certain vertebrates, and several microorganisms, such as E. coli and yeast. The glyoxylate cycle allows these organisms to use fats for the synthesis of carbohydrates, a task which most vertebrates, including humans, cannot perform. The glyoxylate cycle, avoids the steps in the citric acid cycle (TCA cycle) where carbon is lost in the form of CO2. The two initial stages of this cycle are identical to those of the TCA cycle: acetate -> citrate -> isocitrate. The next step, however, is different: instead of decarboxylation, isocitrate undergoes cleavage into succinate and glyoxylate (the latter gives the cycle its name). Succinate can be channeled directly into the citric acid cycle and eventually form oxaloacetate. Glyoxylate condenses with acetyl-CoA, yielding malate. Both malate and oxaloacetate can be converted into phosphoenolpyruvate and gluconeogenesis can be initiated. The net result of the glyoxylate cycle is therefore the production of glucose from fatty acids. In plants the glyoxylate cycle occurs in special peroxisomes which are called glyoxysomes. Vertebrates cannot perform the cycle because they lack its two key enzymes: isocitrate lyase and malate synthase. |
None - {{∅}} |
None - {{∅},{t}} |
Unexplained |
|
| UCR00351 |
CoA + citrate = H(2)O + acetyl-CoA + oxaloacetate |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
| UER00720 |
(S)-malate from isocitrate: step 2/2~1 H(2)O + 1 acetyl-CoA + 1 glyoxylate => 1 (S)-malate + 1 CoA. |
None - {{∅}} |
None - {{∅}} |
Unexplained |
|
| ULS00353 |
(S)-malate from isocitrate |
None - {{∅}} |
None - {{∅}} |
Unexplained |
|
| UER00721 |
oxaloacetate from (S)-malate: step 1/1~1 (S)-malate + 1 NAD(+) => 1 H(+) + 1 NADH + 1 oxaloacetate. |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|