Get results CSV file
Prior-Knowledge Description Expectation Prediction Conclusion Leaf Statistics
UPA00359 lipid IV(A) biosynthesis~Biosynthesis of lipid IV(A), the endotoxically inactive LPS lipid A precursor. Lipid A is one of the three components of lipopolysaccharide (LPS). It contains unusual fatty acids (e.g. hydroxy-myristic acid) and is inserted into the outer membrane while the rest of the LPS projects from the surface. Lipid A, the potent macrophage-activating component primarily responsible for LPS endotoxin activity, is a phosphorylated glucosamine disaccharide carrying long-chain saturated fatty acid (FA) substituents that anchor LPS in the outer membrane. Lipid A is similar for all Gram-negative Enterobacteriaceae, and synthetic lipid A produces effects identical to that isolated from Escherichia coli in both in vitro and in vivo endotoxin tests. None - {{∅}} None - {{∅}} Unexplained
UCR04606 UDP-2,3-bis(3-hydroxytetradecanoyl)-D-glucosamine + lipid X = 2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-alpha-D-glucosaminyl-1,6-beta-D-glucosamine 1-phosphate + UDP None - {{∅}} None - {{∅}} Unexplained
UER00480 lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 4/6~1 H(2)O + 1 UDP-2,3-bis(3-hydroxytetradecanoyl)-D-glucosamine => 1 UMP + 1 lipid X. None - {{∅}} None - {{∅}} Unexplained
UCR04550 UDP-2,3-bis(3-hydroxytetradecanoyl)-D-glucosamine + acyl-carrier protein = (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine None - {{∅}} None - {{∅}} Unexplained
ULS00229 lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine None - {{∅}} None - {{∅}} Unexplained
UCR04657 2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-alpha-D-glucosaminyl-1,6-beta-D-glucosamine 1-phosphate + ATP = ADP + lipid IV(A) None - {{∅}} None - {{∅}} Unexplained
UER00481 lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6~1 UDP-2,3-bis(3-hydroxytetradecanoyl)-D-glucosamine + 1 lipid X => 1 2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-alpha-D-glucosaminyl-1,6-beta-D-glucosamine 1-phosphate + 1 UDP. None - {{∅}} None - {{∅}} Unexplained
VariantPath-1-ULS00229 None - {{∅}} None - {{∅}} Unexplained
VariantPath-2-ULS00229 None - {{∅}} None - {{∅}} Unexplained
UER00479 lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 3/6~1 (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + 1 UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine => 1 UDP-2,3-bis(3-hydroxytetradecanoyl)-D-glucosamine + 1 acyl-carrier protein. None - {{∅}} None - {{∅}} Unexplained
UER00477 lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6~1 (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + 1 UDP-N-acetyl-alpha-D-glucosamine => 1 UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine + 1 acyl-carrier protein. None - {{∅}} None - {{∅}} Unexplained
UCR04567 (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + UDP-N-acetyl-alpha-D-glucosamine = UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine + acyl-carrier protein None - {{∅}} None - {{∅}} Unexplained
UCR04549 H(2)O + UDP-2,3-bis(3-hydroxytetradecanoyl)-D-glucosamine = UMP + lipid X None - {{∅}} None - {{∅}} Unexplained
UCR04587 H(2)O + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine = UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine + acetate None - {{∅}} None - {{∅}} Unexplained
UER00482 lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 6/6~1 2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-alpha-D-glucosaminyl-1,6-beta-D-glucosamine 1-phosphate + 1 ATP => 1 ADP + 1 lipid IV(A). None - {{∅}} None - {{∅}} Unexplained
UER00478 lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6~1 H(2)O + 1 UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine => 1 UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine + 1 acetate. None - {{∅}} None - {{∅}} Unexplained