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Prior-Knowledge Description Expectation Prediction Conclusion Leaf Statistics
UER00943 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2~1 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole => 1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate. True - {{t}} True - {{t}} Confirmed presence
UER00134 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (formate route): step 1/1~1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + 1 ATP + 1 formate => 1 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + 1 ADP + 1 phosphate. None - {{∅}} None - {{∅}} Unexplained
ULS00056 IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide None - {{∅}} True - {{t}} Unconfirmed presence
UCR04558 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + L-glutamate True - {{t}} True - {{t}} Confirmed presence
UER00170 formate from 10-formyl-5,6,7,8-tetrahydrofolate: step 1/1~1 10-formyl-5,6,7,8-tetrahydrofolate + 1 H(2)O => 1 5,6,7,8-tetrahydrofolate + 1 formate. True - {{t}} True - {{t}} Confirmed presence
UCR04144 5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + N(1)-(5-phospho-D-ribosyl)glycinamide + phosphate True - {{t}} True - {{t}} Confirmed presence
VariantPath-11-UPA00074 None - {{∅}} None - {{∅},{t}} Unexplained
MUER19 Meta-UER 19~1 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide + 1 L-glutamine => 1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + 1 D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + 1 L-glutamate. True - {{∅},{t}} True - {{t}} Confirmed presence
ULS00051 N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (10-formyl THF route) None - {{∅}} True - {{t}} Unconfirmed presence
VariantPath-10-UPA00074 None - {{∅}} None - {{∅},{t}} Unexplained
UCR07405 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate True - {{t}} True - {{t}} Confirmed presence
ULS00050 N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate None - {{∅}} True - {{t}} Unconfirmed presence
ULS00052 N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (formate route) None - {{∅}} True - {{t}} Unconfirmed presence
UER00132 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2~1 (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinic acid => 1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + 1 fumarate. True - {{t}} True - {{t}} Confirmed presence
ULS00067 formate from 10-formyl-5,6,7,8-tetrahydrofolate None - {{∅}} True - {{t}} Unconfirmed presence
UER00942 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 1/2~1 5-amino-1-(5-phospho-D-ribosyl)imidazole + 1 ATP + 1 bicarbonate => 1 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + 1 ADP + 1 phosphate. True - {{t}} True - {{t}} Confirmed presence
VariantPath-8-UPA00074 None - {{∅}} True - {{t}} Unconfirmed presence
UCR04560 10-formyl-5,6,7,8-tetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide = 5,6,7,8-tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide True - {{t}} True - {{t}} Confirmed presence
ULS00472 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route) None - {{∅}} True - {{t}} Unconfirmed presence
VariantPath-9-UPA00074 None - {{∅}} None - {{∅},{t}} Unexplained
UCR01072 5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + H(2)O + L-glutamine True - {{t}} True - {{t}} Confirmed presence
UCR07404 5-amino-1-(5-phospho-D-ribosyl)imidazole + ATP + bicarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + phosphate True - {{t}} True - {{t}} Confirmed presence
UCR04325 10-formyl-5,6,7,8-tetrahydrofolate + N(1)-(5-phospho-D-ribosyl)glycinamide = 5,6,7,8-tetrahydrofolate + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide True - {{t}} True - {{t}} Confirmed presence
UER00127 N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (formate route): step 1/1~1 ATP + 1 N(1)-(5-phospho-D-ribosyl)glycinamide + 1 formate => 1 ADP + 1 N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + 1 phosphate. None - {{∅}} True - {{t}} Unconfirmed presence
ULS00055 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (formate route) None - {{∅}} None - {{∅}} Unexplained
UCR06974 ATP + N(1)-(5-phospho-D-ribosyl)glycinamide + formate = ADP + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + phosphate True - {{t}} True - {{t}} Confirmed presence
UER00133 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1~1 10-formyl-5,6,7,8-tetrahydrofolate + 1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide => 1 5,6,7,8-tetrahydrofolate + 1 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. True - {{t}} True - {{t}} Confirmed presence
UER00130 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (carboxylase route): step 1/1~1 5-amino-1-(5-phospho-D-ribosyl)imidazole + 1 CO(2) => 1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate. None - {{∅}} None - {{∅}} Unexplained
ULS00473 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate None - {{∅}} True - {{t}} Unconfirmed presence
ULS00448 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide None - {{∅}} True - {{t}} Unconfirmed presence
UER00131 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2~1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + 1 ATP + 1 L-aspartate => 1 (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinic acid + 1 ADP + 1 phosphate. True - {{t}} True - {{t}} Confirmed presence
VariantPath-7-UPA00074 None - {{∅}} None - {{∅},{t}} Unexplained
VariantPath-6-UPA00074 None - {{∅}} True - {{t}} Unconfirmed presence
VariantPath-5-UPA00074 None - {{∅}} True - {{t}} Unconfirmed presence
UER00124 N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2~1 5-phospho-alpha-D-ribose 1-diphosphate + 1 H(2)O + 1 L-glutamine => 1 5-phospho-beta-D-ribosylamine + 1 L-glutamate + 1 diphosphate. True - {{t}} True - {{t}} Confirmed presence
UCR04591 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + ATP + L-aspartate = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinic acid + ADP + phosphate True - {{t}} True - {{t}} Confirmed presence
VariantPath-4-UPA00074 None - {{∅}} True - {{t}} Unconfirmed presence
VariantPath-3-UPA00074 None - {{∅}} None - {{∅},{t}} Unexplained
UCR04209 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO(2) None - {{∅}} None - {{∅}} Unexplained
ULS00471 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (carboxylase route) None - {{∅}} None - {{∅}} Unexplained
UCR01127 H(2)O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide True - {{t}} True - {{t}} Confirmed presence
UCR00944 10-formyl-5,6,7,8-tetrahydrofolate + H(2)O = 5,6,7,8-tetrahydrofolate + formate True - {{t}} True - {{t}} Confirmed presence
ULS00054 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route) None - {{∅}} True - {{t}} Unconfirmed presence
UER00129 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2~1 2-formamido-N(1)-(5-phospho-D-ribosyl)acetamidine + 1 ATP => 1 5-amino-1-(5-phospho-D-ribosyl)imidazole + 1 ADP + 1 phosphate. True - {{t}} True - {{t}} Confirmed presence
UER00135 IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1~1 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide => 1 H(2)O + 1 IMP. None - {{∅}} True - {{t}} Unconfirmed presence
VariantPath-1-UPA00074 None - {{∅}} None - {{∅},{t}} Unexplained
VariantPath-2-UPA00074 None - {{∅}} None - {{∅},{t}} Unexplained
UPA00074 IMP biosynthesis via de novo pathway~The formation from simpler components of purine nucleotide IMP (inosine 5'phosphate). None - {{∅}} True - {{t}} Unconfirmed presence
UER00128 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2~1 ATP + 1 H(2)O + 1 L-glutamine + 1 N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide => 1 2-formamido-N(1)-(5-phospho-D-ribosyl)acetamidine + 1 ADP + 1 L-glutamate + 1 phosphate. True - {{t}} True - {{t}} Confirmed presence
UCR04559 (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinic acid = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + fumarate True - {{t}} True - {{t}} Confirmed presence
ULS00470 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide None - {{∅}} True - {{t}} Unconfirmed presence
UCR06975 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + ATP + formate = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + ADP + phosphate None - {{∅}} None - {{∅}} Unexplained
UER00126 N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (10-formyl THF route): step 1/1~1 10-formyl-5,6,7,8-tetrahydrofolate + 1 N(1)-(5-phospho-D-ribosyl)glycinamide => 1 5,6,7,8-tetrahydrofolate + 1 N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide. True - {{t}} True - {{t}} Confirmed presence
UER00125 N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2~1 5-phospho-beta-D-ribosylamine + 1 ATP + 1 glycine => 1 ADP + 1 N(1)-(5-phospho-D-ribosyl)glycinamide + 1 phosphate. True - {{t}} True - {{t}} Confirmed presence
UCR04208 2-formamido-N(1)-(5-phospho-D-ribosyl)acetamidine + ATP = 5-amino-1-(5-phospho-D-ribosyl)imidazole + ADP + phosphate True - {{t}} True - {{t}} Confirmed presence
UCR04463 ATP + H(2)O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide = 2-formamido-N(1)-(5-phospho-D-ribosyl)acetamidine + ADP + L-glutamate + phosphate True - {{t}} True - {{t}} Confirmed presence