| UPA00002 |
2-deoxy-D-ribose 1-phosphate degradation~This pathway provides a direct metabolic link between the deoxyribose moiety of nucleosides and central carbon metabolism, independent of the pentose phosphate cycle. Two enzymes provide this link: the phosphopentomutases (PPMs) and 2-deoxyribose 5-phosphate aldolases (DERAs). PPM isomerizes deoxyribose 1-phosphate to deoxyribose 5-phosphate. Subsequently, DERA cleaves the pentose phosphate to acetaldehyde and glyceraldehyde 3-phosphate, allowing further metabolism to obtain carbon and energy. The deoxyribose 1-phosphate is supplied by various nucleoside phosphorylases, such as thymidine phosphorylase, uridine phosphorylase and purine nucleoside phosphorylase, which release the pentose moiety from (deoxy)ribonucleosides, producing (deoxy)ribose 1-phosphate. . |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| ULS00228 |
D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate |
None - {{∅}} |
True - {{t}} |
Unconfirmed presence |
|
| UCR01066 |
2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
| UCR02749 |
2-deoxy-alpha-D-ribose 1-phosphate = 2-deoxy-D-ribose 5-phosphate |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
| UER00468 |
D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2~1 2-deoxy-D-ribose 5-phosphate => 1 D-glyceraldehyde 3-phosphate + 1 acetaldehyde. |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|
| UER00467 |
D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 1/2~1 2-deoxy-alpha-D-ribose 1-phosphate => 1 2-deoxy-D-ribose 5-phosphate. |
True - {{t}} |
True - {{t}} |
Confirmed presence |
|