| GenProp0899 |
nitrile hydratase~The enzyme nitrile hydratase (EC 4.2.1.84) catalyzes the interconversion of an aliphatic amide to a nitrile plus H20. The enzyme is closely related to thiocyanate hydrolase (EC 3.5.5.8). The nitrile hydratase alpha subunit contains active site Cys residues that undergo covalent modification, after which it binds either Fe(III) or Co(III). A CXCC-containing protein related to the cobalamin biosynthesis protein CobW is described as a nitrile hydratase activator and is often found in the nitrile hydratase operon. However, the protein family described by TIGR03889, also commonly annotated as a nitrile hydratase accessory protein, is found in a larger fraction of nitrile hydratase operons. |
None - {{∅}} |
None - {{∅}} |
Unexplained |
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