GenProp0860 |
tryptophan tryptophylquinone modification of methylamine dehydrogenase~The maturation enzyme MauG completes the modification and cross-linking of a pair of Trp residues into the novel cofactor tryptophan tryptophylquinone, or TTQ, in the light chain (MauA) of methylamine dehydrogenase. While some analogous enzyme cofactors are produced autocatalytically from amino acids in the precursor polypeptide, TTQ is produced with aid of the maturation enzyme MauG. MauG is a di-heme enzyme with peroxidase activity, similar to di-heme cytochrome c peroxidases of other biological systems. Interestingly, the pair of modified Trp residues is conserved in MauA homologs in species that have no MauG homolog in the vicinity, suggesting no modification, autocatalytic modification, or a different modification enzyme. |
None - {{∅}} |
None - {{∅}} |
Unexplained |
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